Toba Hiroaki 鳥羽博明

… Alternative Names

Researcher Number	40403745
Affiliation (Current)	2022: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授
Affiliation (based on the past Project Information) *help	2022: 徳島大学, 大学院医歯薬学研究部, 助教 2018 – 2021: 徳島大学, 大学院医歯薬学研究部(医学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教 … More
Review Section/Research Field	Principal Investigator Respiratory surgery / Basic Section 55040:Respiratory surgery-related / General surgery Except Principal Investigator Thoracic surgery / Respiratory surgery / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator 気管支肺胞幹細胞 / iPS細胞 / 急性肺障害 / 移植外科学 / 肺再生医療 / 胎仔肺 / 細胞移植 / ドナー / 肺の再生 / ナフタレン … More Except Principal Investigator 豚 / 胎生期肺組織 / ラット / 移植 / 肺組織移植 / 胎生期肺 / 胎仔肺移植 / 肺の再生 / 肺移植 / ステロイド / 肺線維症 / 肺再生 / gene instability / TaqMan Low Density Array / 呼吸器外科学 / 再生医療 / 経気道的投与 / 肺の発生分化 / 免疫抑制剤 / 肺組織 / 肺の発生 / 肺の分化 / 再生医学 / 胎生期肺移植 / 肺気腫 / マウス / 肺 / 胎仔肺組織移植 / 胎児肺組織移植 / 胎仔肺 / ブレオマイシン / 再生 / 組織修復 / lung regeneration / lung / rat / fetal lung tissue / fetal lung / transplantation / pulmonary fibrosis / bleomycine / クロム肺癌 / DNA修復遺伝子 / 前癌病変 / 発癌 / 発癌過程 / DNA修復遺伝子蛋白 / hMLH / クロム酸塩蓄積量 / chromate lung cancer / DNA mismatch repair gene / pre-malignant lesion / carcinogenesis / 食道癌 / 甲状腺未分化癌 / 肺癌 / 同所性移植モデル / リンパ節転移 / 転移関連遺伝子 / 抗癌剤関連遺伝子 / esophageal cancer / thyroid anaplastic carcinoma / lung cancer / orthotopic implantation model / lymph node metastasis / metastasis related gene / anti cancer agent related gene / 肺organoid / 乳房再建 / 乳腺幹細胞 / 乳汁分泌 / 肺再生医療 / マウス肺移植 / ips細胞 / GFPマウス / 胎児肺 / Luminal型乳癌 / 骨転移 / Lysyl oxidase(LOX) / LOX阻害薬 / iPS細胞 / 気管支断端瘻 / 間葉系幹細胞 Less

iPS細胞から誘導した気管支肺胞幹細胞～その性格とオルガノイドを用いた肺再生研究Principal Investigator
- Principal Investigator
  
  鳥羽博明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Tokushima
間葉系幹細胞による気管支の修復メカニズムの解明　iPS細胞による気管支断端瘻予防
- Principal Investigator
  
  坂本晋一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Tokushima
腫瘍が分泌するLOXはLuminal型乳癌の骨転移予見バイオマーカーになり得る
- Principal Investigator
  
  兼松美幸
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The University of Tokushima
気道・肺の障害・修復と再生におけるp53の役割～p53遺伝子改変ブタを用いた研究Principal Investigator
- Principal Investigator
  
  鳥羽博明
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Tokushima
Generation of functional mammary glands by mammary stem cells
- Principal Investigator
  
  MORIMOTO Masami
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokushima
マウス肺移植による肺再生医療研究の可能性
- Principal Investigator
  
  吉田光輝
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  The University of Tokushima
The attempt for lung regeneration using lung organid (lung cell and tissue transplantation)
- Principal Investigator
  
  KAWAKAMI Yukikiyo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  The University of Tokushima
Intratracheal administration of induced pluripotent stem (iPS) cells induced bronchioloalveolar stem cells (BASCs) can accelerate the repair of injured lung.Principal Investigator
- Principal Investigator
  
  TOBA Hiroaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  The University of Tokushima
Fetal lung fragments implantation into fibrotic lung of a pig model
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kochi National Hospital
  The University of Tokushima
iPS細胞から誘導した気管支肺胞幹細胞を用いた肺の再生Principal Investigator
- Principal Investigator
  
  鳥羽博明
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Respiratory surgery
- Research Institution
  The University of Tokushima
Experimental examination of the pulmonary emphysema treatment with fetal lung tissues transplantation - a pig emphysema model -
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
Fetal lung cell implantation with bronchioalveolar stem cellsPrincipal Investigator
- Principal Investigator
  
  TOBA Hiroaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokushima
Implantation of fetal pig lung fragments into adult rat lung parenchyma-search for a possibility of transbronchial delivery with a bronchoscope-
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
Carcinogenesis mechanism of lung cancer of the chromate industrial workers with chromate exposure -Relationship between DNA mismatch repair hMLH gene and gene instability-
- Principal Investigator
  
  KONDO Kazuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
A study about the anticancer agent-related gene change in the human lung cancer orthotopic implantation model
- Principal Investigator
  
  MIYOSHI Takanori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Department of Clinical Research, National Hospital Organization Tokushima National Hospital
  The University of Tokushima
Lung regeneration : implantation of fetal rat lung fragments into adult rat lung with bleomycine induced fibrosis
- Principal Investigator
  
  SEKIYAMA Syoji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima

All 2016 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model2016
- Author(s)
  Uyama K, Sakiyama S, Yoshida M, MD, Kenzaki K, Toba H, Kawakami Y, Okumura K, Takizawa H, Kondo K and Tangoku A.
- Journal Title
  
  J Med Invest
  
  Volume: 63
- NAID
  130005245852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462127
[Journal Article] Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis2012
- Author(s)
  Toba H, Sakiyama S, Koichiro kenzaki, Yukikiyo kawakami, Koh Uyama, Yoshimi Bando, Akira Tangoku
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: vol.143 Pages: 1429-1435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592062
[Journal Article] Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis.2012
- Author(s)
  Toba H, Sakiyama S, et al.
- Journal Title
  
  J Thorac Cardiovasc Surg.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 肺の再生・修復を目的とした胎生期肺組織移植2012
- Author(s)
  先山正二、監崎孝一郎、鳥羽博明、宇山攻、梶浦耕一郎、中川靖士、吉田光輝、川上行奎、滝沢宏光、近藤和也、丹黒章
- Organizer
  第29回日本呼吸器外科学会総会
- Place of Presentation
  秋田キャッスルホテル(秋田県)
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 胎仔肺移植による肺気腫自然発症モデルマウス肺修復の試み2011
- Author(s)
  宇山攻、先山正二、鳥羽博明、吉田光輝、監崎孝一郎、丹黒章
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 豚を用いた胎生期肺組織移植の実験的検討2010
- Author(s)
  先山正二, 監崎孝一郎, 鳥羽博明, NarmisheekhKhasag, 宇山攻, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本外科学会雑誌(0301-4894)111巻臨増2Page648
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] Sex-mismatchを用いたラット胎仔肺移植モデルのドナー細胞の組織学的検討2010
- Author(s)
  監崎孝一郎, 先山正二, 宇山攻, 鳥羽博明, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本外科学会雑誌(0301-4894)111巻臨増2Page210
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 豚を用いた胎生期肺組織移植の実験的検討ラットで得られた知見との比較を含めて2010
- Author(s)
  先山正二, 監崎孝一郎, 鳥羽博明, NarmisheekhKhasag, 宇山攻, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本呼吸器外科学会雑誌(0919-0945)24巻3号Page417
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 胎仔肺組織移植により移植したグラフト内でのTTF-1発現の検討2010
- Author(s)
  鳥羽博明
- Organizer
  第63回日本胸部外科学会総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-21791254
[Presentation] 呼吸器外科領域の再生医療ブレオマイシン誘導肺線維症モデルに対する胎仔肺組織移植2009
- Author(s)
  鳥羽博明, 先山正二, 監崎孝一郎, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本呼吸器外科学会雑誌(0919-0945)23巻3号Page350
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] ブレオマイシン誘導肺線維症モデルに対する胎仔肺組織移植2009
- Author(s)
  鳥羽博明
- Organizer
  第26回日本呼吸器外科学会総会
- Place of Presentation
  北九州国際会議場(北九州市)
- Year and Date
  2009-05-14
- Data Source
  KAKENHI-PROJECT-21791254
[Presentation] GFPラットを用いた胎仔肺移植モデルのドナー組織間再融合の組織学的検討2008
- Author(s)
  監崎孝一郎, 先山正二, 宇山攻, 松岡永, 鳥羽博明, 滝沢宏光, 広瀬由紀子, 近藤和也, 坂東良美, 丹黒章
- Organizer
  日本外科学会雑誌(0301-4894)109巻臨増2Page213
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 胎生期肺組織移植における気道系の分化とbranchingに関する検討
- Author(s)
  先山正二、鳥羽博明、監崎孝一郎、坪井光弘、梶浦耕一郎、中川靖士、吉田光輝、川上行奎、滝沢宏光、近藤和也、丹黒章
- Organizer
  第37回日本呼吸器内視鏡学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-15
- Data Source
  KAKENHI-PROJECT-26462127

1. KAWAKAMI Yukikiyo (00596249)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. SAKIYAMA Shoji (60291986)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
3. TAKIZAWA HIromitsu (90332816)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
4. YOSHIDA Mitsuteru (30403710)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
5. KONDO Kazuya (10263815)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. KENZAKI Koichirou (70325265)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
7. MIYOSHI Takanori (20346612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. MORIMOTO Masami (90563817)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 河北直也 (60522266)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. KAJIURA Koichiro (60596253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. 丹黒章 (10197593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 宇山攻 (90437658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 坪井光弘 (10711872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 谷原史倫 (90754680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 平田真樹 (10815583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 兼松美幸 (90836305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 武知浩和 (70380102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 坂本晋一 (30740675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 高嶋美佳 (70596254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Toba Hiroaki 鳥羽 博明

TOBA Hiroaki 鳥羽 博明

Research Projects

Research Products

Co-Researchers

iPS細胞から誘導した気管支肺胞幹細胞～その性格とオルガノイドを用いた肺再生研究Principal Investigator

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気道・肺の障害・修復と再生におけるp53の役割～p53遺伝子改変ブタを用いた研究Principal Investigator

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Intratracheal administration of induced pluripotent stem (iPS) cells induced bronchioloalveolar stem cells (BASCs) can accelerate the repair of injured lung.Principal Investigator

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Principal Investigator

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iPS細胞から誘導した気管支肺胞幹細胞を用いた肺の再生Principal Investigator

Principal Investigator

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Principal Investigator

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Fetal lung cell implantation with bronchioalveolar stem cellsPrincipal Investigator

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Toba Hiroaki 鳥羽博明

TOBA Hiroaki 鳥羽博明

[Presentation] 豚を用いた胎生期肺組織移植の実験的検討ラットで得られた知見との比較を含めて2010