MOCHIZUKI Yasushi 望月保志

Researcher Number	40404256
Affiliation (Current)	2025: 長崎大学, 病院(医学系), 准教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 長崎大学, 病院(医学系), 准教授 2014 – 2016: 長崎大学, 病院(医学系), 講師 2013: 長崎大学, 大学病院, 講師
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Urology / Basic Section 09070:Educational technology-related
Keywords	Principal Investigator 腎細胞癌 / 治療戦略 / 分子機構解明 / 新規治療薬 / 新規治療戦略 / 腎癌 / フェロトーシス / 悪性腫瘍 / 鉄動態 / 腎臓 … More / 治療効果 / 薬物療法 / 腫瘍学 / 治療標的 / 機能解明 / 癌関連分子同定 / 肉腫様腎癌 / 標的分子 / 予後不良因子 / 肉腫様腎細胞癌 … More Except Principal Investigator 腎細胞癌 / 膀胱癌 / 映像教材 / ロボット手術 / 教育システム / 酸化ストレス / シリコン微細粒子 / 尿細管間質 / 線維化 / 腎移植 / 腸管 / バイオ３Dプリンター / 蠕動運動 / ３Dバイオプリンティング / ラベリング / インドシアニングリーン / バイオ3Dプリンティング / 再生 / 再生医療 / リンパ管 / バイオ３Dプリンティング / スフェロイド / インドシアニングリーンラベリング / 尿管 / データベース / 倫理委員会 / 細胞培養 / リンパ球 / 微小環境 / 癌微小環境 / 腫瘍免疫 / 腎癌 / MSCF / 治療効果予測因子 / 転移性腎癌 / ローヤルゼリー / マクロファージ / TGF-β / TNF-α / 癌免疫 / T24 / Fer / 遊走能 / 細胞遊走 / 細胞浸潤 / 細胞増殖 / 化学療法 / TUBB3 / 予後 / 癌細胞浸潤 / 癌細胞増殖 / 尿路癌 / Fes / 免疫染色 / HO-1 / 表在性膀胱癌 / 泌尿器癌 / 化学発癌マウスモデル / 血管新生 / Thrombospondin / Human antigen R / Hemeoxygenase-1 / TWIST / Angiogenesis / Thrombospondins / 4N1K-peptide Less

Establishment of an innovative method to suppress renal tubulointerstitial fibrosis after kidney transplantation
- Principal Investigator
  
  今村亮一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
ロボット支援手術チームが作る映像教材とトレーニング機器による教育システムの構築
- Principal Investigator
  
  光成健輔
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 09070:Educational technology-related
- Research Institution
  Nagasaki University
Regeneration of the ureter with a scaffold-free living cell structure
- Principal Investigator
  
  Takagi Katsunori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
Elucidation of molecular mechanism of ferroptosis and construction of new therapeutic strategy in renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  MOCHIZUKI Yasushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
analysis of the effect of changes in the microenvironment around cancer on renal cancer stem cells: development of new treatment strategies
- Principal Investigator
  
  Ohba Kojiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
Investigation on usefulness of Fes / Fer as new therapeutic target and predictive factor in urothelial cancer
- Principal Investigator
  
  TAKEHARA Kosuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Evaluation of usefulness of sarcomatoid renal cell carcinoma experiment model using clinical specimen data and search for new therapeutic targets.Principal Investigator
- Principal Investigator
  
  MOCHIZUKI Yasushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Analysis of the pathological role of HO-1 in kidney cancer cells and cancer interstitial tissue and construction of new therapeutic strategies
- Principal Investigator
  
  MATSUO Tomohiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Investigation on clinicopathological signficance and tumor suppressive effects of 4N1K-peptide in bladder cancer
- Principal Investigator
  
  MIYATA Yasuyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University

All 2023 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation

[Journal Article] Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique2022
- Author(s)
  Takagi K, Matsumoto K, Taniguchi D, Machino R, Uchida F, Hara R, Oishi K, Yamane Y, Iwatake M, Eguchi M, Mochizuki Y, Nakayama K, Nagayasu T.
- Journal Title
  
  acta biomaterialia
  
  Volume: 22 Pages: 1742-7061
- DOI
  10.1016/j.actbio.2022.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09541
[Journal Article] Effect of oral intake of royal jelly on endothelium function in hemodialysis patients: study protocol for multicenter, double-blind, randomized control trial2021
- Author(s)
  Kojiro Ohba , Yasuyoshi Miyata , Takeaki Shinzato , Satoshi Funakoshi , Kanenori Maeda , Tomohiro Matsuo , Kensuke Mitsunari , Yasushi Mochizuki , Tomoya Nishino , Hideki Sakai
- Journal Title
  
  Trials
  
  Volume: 22 Issue: 1 Pages: 950-950
- DOI
  10.1186/s13063-021-05926-x
- NAID
  120007190859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09731
[Journal Article] Oral intake of royal jelly improves anti?cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF?α and TGF?β in renal cell carcinoma: A preliminary study based on a randomized double?blind clinical trial2020
- Author(s)
  Miyata Yasuyoshi、Araki Kyohei、Ohba Kojiro、Mastuo Tomhiro、Nakamura Yuichiro、Yuno Tsutomu、Mukai Yuta、Otsubo Asato、Mitsunari Kensuke、Mochizuki Yasushi、Sakai Hideki
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 13 Pages: 29-29
- DOI
  10.3892/mco.2020.2099
- Data Source
  KAKENHI-PROJECT-18K09170
[Journal Article] Oral Intake of Royal Jelly Has Protective Effects Against Tyrosine Kinase Inhibitor-Induced Toxicity in Patients with Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled Trial.2018
- Author(s)
  Araki K, Miyata Y, Ohba K, Nakamura Y, Matsuo T, Mochizuki Y, Sakai H.
- Journal Title
  
  Medicines
  
  Volume: 6 Issue: 1 Pages: 1-11
- DOI
  10.3390/medicines6010002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09170
[Journal Article] Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer.2015
- Author(s)
  Miyata Y, Mitsunari K, Akihiro A, Watanabe SI, Mochizuki Y, Sakai H.
- Journal Title
  
  Molucular and Clinical Oncology
  
  Volume: 3 Pages: 287-294
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462487
[Presentation] 腹腔鏡下折鶴トレーニングについて～1000羽作成して～2023
- Author(s)
  上田康史、大木雅晴、林田靖’、松島俊樹、森慎太郎、土山彩華、福島始、河田賢、野田祐介、大坪亜紗斗、光成健輔、松尾朋博、大庭康司郎、望月保志、今村亮一
- Organizer
  小切開・鏡視外科学会
- Data Source
  KAKENHI-PROJECT-23K02713
[Presentation] 透析療法とOncoNephrology, 透析腎癌の薬物療法, オンコネフロロジストの視点で再考する2021
- Author(s)
  望月保志, 大庭康司郎, 宮田康好, 酒井英樹
- Organizer
  日本透析医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K09731
[Presentation] YAP expression plays important roles in malignant aggressiveness by regulating the infiltration of CD57+ natural killer cells, CD68+ macrophages, and mast cells and the expression of VEGF-A and PD-L1 in clear cell renal cell carcinoma.2021
- Author(s)
  Ohba K., Miyata Y., Harada J., Matsuda T., Kondo T., Otsubo A., Mukae Y., Ito H., Kurata H., Mitsunari K., Matsuo T., Mochizuki Y., Sakai H.
- Organizer
  The 116th American Urological Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] 当科におけるaxitinibの治療成績2019
- Author(s)
  迎祐太, 大庭康司郎, 上田康史, 中村裕一郎, 相良祐次, 松尾朋博, 望月保志, 宮田康好, 酒井英樹
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Case study of inferior vena caval tumor thrombus in patients with renal cell carcinoma2019
- Author(s)
  Kojiro Ohba, Hiroki Kurata, Yuta Mukae, Yuichiro Nakamura, Hiromi Nakanishi, Yuji Sagara, Tomohiro Matsuo, Yasushi Mochizuki, Yasuyoshi Miyata, Hideki Sakai
- Organizer
  第50回腎癌研究会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Initial experience of nivolumab treatment for patients with metastatic renal cell carcinoma.2018
- Author(s)
  Kojiro Ohba, Hidenori Ito, Yuta Mukae, Yuichiro Nakamura, Hiromi Nakanishi, Yuji Sagara, Tomohiro Matsuo, Yasushi Mochizuki, Yasuyoshi Miyata, Hideki Sakai
- Organizer
  第56回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Intake of royal jelly prevents sunitinib-induced appetite loss in patients with renal cell carcinoma: Correlation with serum levels of transforming growth factor-β and macrophage colony-stimulating factor.2018
- Author(s)
  Kojiro Ohba, Yasuyoshi Miyata, Yuichiro Nakamura, Kyohei Araki, Takuji Yasuda, Yuji Sagara, Tomohiro Matuso, Yasushi Mochizuki, Hideki Sakai
- Organizer
  113th AUA annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] 初期治療として腎摘除を施行しなかった腎細胞癌症例の臨床的検討2018
- Author(s)
  大庭　康司郎、原田　淳樹、荒木　杏平、中西　裕美、相良　祐次、松尾　朋博、望月　保志、宮田　康好、酒井　英樹
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Nivolumabによるimmuno-related adverse events（irAE）の経験2018
- Author(s)
  大庭　康司郎、松田　剛、中西　裕美、安田　拓司、相良　祐次、松尾　朋博、望月　保志、宮田　康好、酒井　英樹
- Organizer
  第49回腎癌研究会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Pathological and prognostic significance of densities ofCD57+ (natural killer cells),CD68+ (macrophage), andmastcells in renal cell carcinoma tissues2017
- Author(s)
  Yasushi Mochizuki
- Organizer
  European Association of Urology 2017
- Place of Presentation
  ロンドン（英国）
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10595
[Presentation] Pathological and prognostic significance of densities of CD57+ (natural killer cells), CD68+ (macrophage), and mast cells in renal cell carcinoma tissues2017
- Author(s)
  Yasushi Mochizuki
- Organizer
  The Congress of European association of Urology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10595

1. MIYATA Yasuyoshi (60380888)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. TAKEHARA Kosuke (40580345)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Ohba Kojiro (20593825)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
4. MATSUO Tomohiro (60622024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. SAKAI Hideki (40235122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Takagi Katsunori (90635856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 中山功一 (50420609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 江口正倫 (70585405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 永安武 (80284686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 松本桂太郎 (80404268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 町野隆介 (90728081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 谷口大輔 (20773758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 山根裕介 (90457549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 今村亮一 (40456976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 山中和明 (10648017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 中澤成晃 (80759530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 光成健輔 (70866657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 古里文吾 (40770409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKANISHI Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAMURA Yuichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ARAKI Kyohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MOCHIZUKI Yasushi 望月 保志

Research Projects

Research Products

Co-Researchers

Establishment of an innovative method to suppress renal tubulointerstitial fibrosis after kidney transplantation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ロボット支援手術チームが作る映像教材とトレーニング機器による教育システムの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regeneration of the ureter with a scaffold-free living cell structure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism of ferroptosis and construction of new therapeutic strategy in renal cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

analysis of the effect of changes in the microenvironment around cancer on renal cancer stem cells: development of new treatment strategies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation on usefulness of Fes / Fer as new therapeutic target and predictive factor in urothelial cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of usefulness of sarcomatoid renal cell carcinoma experiment model using clinical specimen data and search for new therapeutic targets.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the pathological role of HO-1 in kidney cancer cells and cancer interstitial tissue and construction of new therapeutic strategies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation on clinicopathological signficance and tumor suppressive effects of 4N1K-peptide in bladder cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Regeneration of the ureter using a scaffold-free live-cell structure created with the bio-three-dimensional printing technique2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of oral intake of royal jelly on endothelium function in hemodialysis patients: study protocol for multicenter, double-blind, randomized control trial2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Oral intake of royal jelly improves anti?cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF?&alpha; and TGF?&beta; in renal cell carcinoma: A preliminary study based on a randomized double?blind clinical trial2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral Intake of Royal Jelly Has Protective Effects Against Tyrosine Kinase Inhibitor-Induced Toxicity in Patients with Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled Trial.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer.2015

MOCHIZUKI Yasushi 望月保志

[Journal Article] Oral intake of royal jelly improves anti?cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF?α and TGF?β in renal cell carcinoma: A preliminary study based on a randomized double?blind clinical trial2020