Katayama Kazuhiro 片山和浩

… Alternative Names

片山和浩カタヤマカズヒロ

KATAYAMA Kazuhiro 片山和浩

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Researcher Number	40406963
Other IDs	https://orcid.org/0000-0003-4232-7661
Affiliation (Current)	2024: 日本大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 日本大学, 薬学部, 教授 2011 – 2012: 慶應義塾大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Medical pharmacy
Keywords	Principal Investigator 獲得変異 / シグナル / FLT3 / バイパスシグナル / 重複耐性 / FLT3阻害薬 / 急性骨髄性白血病 / PPP2R3C / PP5 / Ube2r1 … More / FBXO15 / ユビキチン化 / P-糖タンパク質 / ABC 輸送体 / 代謝学 / 薬物動態 Less

Molecular mechanisms of duplicate resistance to FLT3 inhibitors in acute myeloid leukemiaPrincipal Investigator
- Principal Investigator
  
  片山和浩
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Nihon University
Basic research for development of new drugs based on the regulationof ABC transporters activity and expressionPrincipal Investigator
- Principal Investigator
  
  KATAYAMA Kazuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University

All 2023 2022 2021 2013 2012 2011

All Journal Article Presentation

[Journal Article] Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML2022
- Author(s)
  Yamatani K, Ai T, Saito K, Suzuki K, Hori A, Kinjo S, Ikeo K, Ruvolo V, Zhang W, Mak PY, Kaczkowski B, Harada H, Katayama K, Sugimoto Y, Myslinski J, Hato T, Miida T, Konopleva M, Hayashizaki Y, Carter BZ, Tabe Y, Andreeff M
- Journal Title
  
  Translational Oncology
  
  Volume: 18 Pages: 101354-101354
- DOI
  10.1016/j.tranon.2022.101354
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08824, KAKENHI-PROJECT-21K06585, KAKENHI-PROJECT-21K07226, KAKENHI-PROJECT-21K20913, KAKENHI-PROJECT-19KK0221, KAKENHI-PROJECT-19H04355
[Journal Article] Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.2022
- Author(s)
  Naoya Araki, Tokio Morita, Takeshi Akiyoshi, Hiroki Kataoka, Kodai Yajima, Kazuhiro Katayama, Ayuko Imaoka, Hisakazu Ohtani.
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 46 Pages: 100464-100464
- DOI
  10.1016/j.dmpk.2022.100464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06585
[Journal Article] Inhibitory effects of cranberry juice and its ingredients on intestinal OATP1A2 and OATP2B1: Identification of avicularin as a novel inhibitor2022
- Author(s)
  Morita T, Akiyoshi T, Tsuchitani T, Kataoka H, Araki N, Yajima K, Katayama K, Imaoka A, Ohtani H
- Journal Title
  
  J Agric Food Chem
  
  Volume: 70 Issue: 10 Pages: 3310-3320
- DOI
  10.1021/acs.jafc.2c00065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07173, KAKENHI-PROJECT-21K06585
[Journal Article] Viral vector purification with thermoresponsive-anionic mixed polymer brush modified beads-packed column2022
- Author(s)
  Nagase Kenichi、Kitazawa Sakiko、Kogure Toshihiko、Yamada Sota、Katayama Kazuhiro、Kanazawa Hideko
- Journal Title
  
  Separation and Purification Technology
  
  Volume: 286 Pages: 120445-120445
- DOI
  10.1016/j.seppur.2022.120445
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05233, KAKENHI-PROJECT-19H02447, KAKENHI-PROJECT-21K06585
[Journal Article] Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants.2022
- Author(s)
  Hongye Han, Takeshi Akiyoshi, Tokio Morita, Hiroki Kataoka, Kazuhiro Katayama, Kodai Yajima, Ayuko Imaoka, Hisakazu Ohtani.
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 47 Pages: 100470-100470
- DOI
  10.1016/j.dmpk.2022.100470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06585
[Journal Article] Inhibitory Potency and pH-dependence of OATP2B1 Inhibitors.2021
- Author(s)
  Sato R, Akiyoshi T, Morita T, Katayama K, Yajima K, Kataoka H, Imaoka A, Ohtani H.
- Journal Title
  
  Drug Metabol Pharmacokinet
  
  Volume: 41 Pages: 100416-100416
- DOI
  10.1016/j.dmpk.2021.100416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07173, KAKENHI-PROJECT-21K06585
[Journal Article] RSK Inhibition Induces Apoptosis by Downregulating Protein Synthesis in a Variety of Acute Myeloid Leukemia Cell Lines2021
- Author(s)
  Katayama Kazuhiro、Nishihata Ayane
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 12 Pages: 1843-1850
- DOI
  10.1248/bpb.b21-00531
- NAID
  130008123418
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06585
[Journal Article] FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells.2013
- Author(s)
  Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 6 Pages: 694-702
- DOI
  10.1111/cas.12145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-23790196
[Journal Article] Expression of human ABCB5 confers resistance to taxanes and anthracyclines2012
- Author(s)
  Takaaki Kawanobe
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: VOL.418 Issue: 4 Pages: 736-741
- DOI
  10.1016/j.bbrc.2012.01.090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-23790196
[Journal Article] Expression of human ABCB5 confers resistance to taxanes and anthracyclines.2012
- Author(s)
  Kawanobe T, Kogure S, Nakamura S, Sato M, Katayama K, Mitsuhashi J, Noguchi K, Sugimoto Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 418 Pages: 736-736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790196
[Journal Article] Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encode d vFLIP in chemosensitization to bleomycin2011
- Author(s)
  Yuri Masuda
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: VOL.415 Issue: 2 Pages: 305-312
- DOI
  10.1016/j.bbrc.2011.10.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-23790196
[Journal Article] Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP in chemosensitization to bleomycin.2011
- Author(s)
  Masuda Y, Noguchi K, Segawa H, Tanaka N, Katayama K, Mitsuhashi J, Sugimoto Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 415 Pages: 305-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790196
[Journal Article] A DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization2011
- Author(s)
  Yasuda A., Noguchi K., Minoshima M., Kashiwazaki G., Kanda T., Katayama K., Mitsuhashi J., Bando T., Sugiyama H., Sugimoto Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102(12) Issue: 12 Pages: 2221-2230
- DOI
  10.1111/j.1349-7006.2011.02098.x
- NAID
  10030246127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590523, KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-23790196
[Presentation] ロウバイ／ソシンロウバイ抽出物による急性骨髄性白血病細胞の増殖抑制2023
- Author(s)
  近藤理佐子、菊地結、大越一輝、羽田紀康、片山和浩
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] リネゾリドとリファンピシンの薬物間相互作用に関わる因子の探索2023
- Author(s)
  井上万莉、辻泰弘、寺田一樹、片山和浩
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] 急性骨髄性白血病細胞におけるFLT3阻害薬重複耐性の分子機構解析2023
- Author(s)
  片山和浩
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] FLT3阻害薬に重複耐性を示す急性骨髄性白血病細胞の耐性機構解析2022
- Author(s)
  片山和浩
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] Characterization of dual resistant AML cells to FLT3 inhibitors2022
- Author(s)
  Kazuhiro Katayama
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] SYDE1 upregulates P-glycoprotein in human colorectal cancer SW620 cells2022
- Author(s)
  Suguru Takeda; Shingo Kondo; Kazuhiro Katayama; Yu Kato; Yoshikazu Sugimoto
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] RSK阻害薬BI-D1870による急性骨髄性白血病細胞の増殖抑制2022
- Author(s)
  片山和浩
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] Molecular mechanisms underlying dual resistance to FLT3 inhibitors in AML cells2021
- Author(s)
  Kazuhiro Katayama
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] RSK阻害薬BI-D1870はタンパク質合成を阻害し、急性骨髄性白血病細胞の増殖を抑制する2021
- Author(s)
  片山和浩
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06585
[Presentation] PP5/PPP2R3C による P- 糖タンパク質/ABCB1 の発現と活性制御2013
- Author(s)
  片山和浩、野口耕司、杉本芳一
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] KSHV由来のRTA/ORF50の機能制御に関するリシン残基の関与2013
- Author(s)
  野口耕司, 橋本幸輝, 片山和浩, 杉本芳一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] PP5/PPP2R3CによるP-糖タンパク質/ABCB1の発現と活性制御2013
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] PP5/PPP2R3CによるP-糖タンパク質／ABCB1の発現制御2013
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] KSHV由来のRTA/ORF50の機能制御に関するリシン残基の役割2012
- Author(s)
  野口耕司, 橋本幸輝, 片山和浩, 杉本芳一
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  グランキューブ大阪（大阪）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] 新規Pim kinase阻害薬の抗腫瘍効果2012
- Author(s)
  近藤慎吾, 三橋純子, 片山和浩, 野口耕司, 中野浩史, 岡部隆義, 杉本芳一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] FBXO15による P-糖タンパク質/ABCB1 の分解制御2012
- Author(s)
  片山和浩、野口耕司、杉本芳一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] がん関連ウイルスKSHV由来の転写因子RTAの機能制御に関する解析2012
- Author(s)
  野口耕司, 原一郎, 橋本幸輝, 片山和浩, 三橋純子, 杉本芳一
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] FBXO15 is an F-box protein in E3 ligase complex for P-glycoprotein.2012
- Author(s)
  Katayama K, Noguchi K, Mitsuhashi J, Sugimoto Y
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] ABCB5発現細胞におけるBSOの影響2012
- Author(s)
  川野辺峻哲, 中村祥代, 三橋純子, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] FBXO15によるP-糖タンパク質/ABCB1の分解制御2012
- Author(s)
  片山和浩, 野口耕司, 三橋純子, 杉本芳一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] Plk阻害による抗有糸分裂効果はカスパーゼの活性化に依存する2012
- Author(s)
  田中伯享, 野口耕司, 片山和浩, 三橋純子, 杉本芳一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] KSHV関連リンパ腫に対するHDAC阻害薬と抗ウイルス薬の相乗効果の分子基盤2012
- Author(s)
  野口耕司, 片山和浩, 杉本芳一
- Organizer
  第16回日本がん分子標的治療学会
- Place of Presentation
  西日本総合展示場（北九州）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] FBXO15 is an F-box protein in E3 ligase complex for P-glycoprotein2012
- Author(s)
  Katayama K, Noguchi K, Sugimoto Y
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] ヒトABCB5のメタボローム解析2012
- Author(s)
  近藤慎吾, 川野辺峻哲, 三橋純子, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] P-糖タンパク質に対するユビキチン E3 リガーゼ FBXO15 の同定と機能解析2012
- Author(s)
  片山和浩、野口耕司、杉本芳一
- Organizer
  第16回日本がん分子標的治療学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] P-糖タンパク質に対するユビキチンE3リガーゼFBX015の同定と機能解析2012
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  第16回日本がん分子標的治療学会
- Place of Presentation
  西日本総合展示場（北九州）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] ヒト大腸がん細胞のSnail誘導上皮間葉転換におけるABC輸送体の発現2012
- Author(s)
  石川宣明, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] KSHV由来のRTA/ORF50の転写活性を変動させる薬物の探索2011
- Author(s)
  原一郎, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東邦大学習志野キャンパス（千葉県）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] EBNA1-OriP結合を阻害するポリアミド化合物によるEBウイルス感染細胞の不死化阻害2011
- Author(s)
  野口耕司、片山和浩、蓑島維文、板東俊和、杉山弘、杉本芳一
- Organizer
  第15回日本がん分子標的治療学会
- Place of Presentation
  ホテル日航東京（東京都）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] ヒトABCB5はATPase活性を有するが、ABCB1の基質は活性に影響を与えない2011
- Author(s)
  川野辺峻哲, 野口耕司, 片山和浩, 三橋純子, 杉本芳一
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東邦大学習志野キャンパス（千葉県）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] ヒトABCB5のATPase活性の検討2011
- Author(s)
  川野辺峻哲、野口耕司、片山和浩、三橋純子、杉本芳一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] P-糖タンパク質/ABCB1 結合タンパク質の同定2011
- Author(s)
  片山和浩、野口耕司、杉本芳一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] ウイルス由来vFLIPによるブレオマイシン誘導G2/M期チェックポイントの制御2011
- Author(s)
  野口耕司、片山和浩、三橋純子、杉本芳一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] P-糖タンパク質/ABCB1結合タンパク質の同定2011
- Author(s)
  片山和浩、野口耕司、三橋純子、杉本芳一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23790196
[Presentation] EBV-induced immortalization is inhibited by polyamide targeting EBNA1-oriP binding.2011
- Author(s)
  Noguchi K, Yasuda A, Katayama K, Mitsuhashi J, Kanda T, Minoshima M, Bando T, Sugiyama H, Sugimoto Y
- Organizer
  XV International Congress of Virology / IUMS2011 Congress
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23790196

1. HARADA Yuka

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# of Collaborated Products: 1 results
2. AKIYOSHI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. NAGASE Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 神田輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 杉本芳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Katayama Kazuhiro 片山 和浩

片山 和浩 カタヤマ カズヒロ

KATAYAMA Kazuhiro 片山 和浩

Research Projects

Research Products

Co-Researchers

Molecular mechanisms of duplicate resistance to FLT3 inhibitors in acute myeloid leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research for development of new drugs based on the regulationof ABC transporters activity and expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML2022

Author(s)

Journal Title

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[Journal Article] Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.2022

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[Journal Article] Inhibitory Potency and pH-dependence of OATP2B1 Inhibitors.2021

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[Journal Article] RSK Inhibition Induces Apoptosis by Downregulating Protein Synthesis in a Variety of Acute Myeloid Leukemia Cell Lines2021

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[Journal Article] FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells.2013

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[Journal Article] Expression of human ABCB5 confers resistance to taxanes and anthracyclines2012

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[Journal Article] Expression of human ABCB5 confers resistance to taxanes and anthracyclines.2012

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[Journal Article] Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encode d vFLIP in chemosensitization to bleomycin2011

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[Journal Article] Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP in chemosensitization to bleomycin.2011

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Katayama Kazuhiro 片山和浩

片山和浩カタヤマカズヒロ

KATAYAMA Kazuhiro 片山和浩