TAKADA Yasunari 高田康成

Researcher Number	40407086
Other IDs
Affiliation (based on the past Project Information) *help	2013: 慶應義塾大学, 医学部, 講師 2008 – 2011: Keio University, 医学部, 講師 2007 – 2008: Keio University, 医学部, 助教 2005 – 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Thoracic surgery / Orthopaedic surgery / Biological Sciences Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator Fos / AP-1 / 腫瘍免疫 / 凍結融解壊死療法 / 4次元解析 / 骨形成 / Fra-1 / Cathepsin K / 骨カップリング / Adenovirus … More / RANKL / Cre-recombinase / Cathepasin K / Osteoclast / Fos conditional KO / lysozme M-Cre / inflammation / colitis / DSS / AOM / NF-κB / AP-l / マクロファージ / 大腸がん / 大腸炎 / LPS / TNF / サイトカイン / NF-ΚB … More Except Principal Investigator 破骨細胞 / 骨芽細胞 / 骨リモデリング / OPG / c-Fos / ephrin / 耳小骨 / Auditory ossicles / cytokine / Osteoclast / Bone remodeling / Osteoimmunology / サイトカイン / エフリン / 骨免疫学 / 発現制御 / 細胞・組織 / 遺伝子 / ミネラリゼーション / メダカ / 転写因子 / 石灰化 / 骨代謝 / Eph / 骨吸収 / 骨細胞 / カップリング / トランスジェニックマウス / Fral / 骨硬化症 / 骨・軟骨代謝 Less

In search for shared regulatory mechanisims of bone mineralization in vertebrates
- Principal Investigator
  
  MATSUO Koichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
転写因子Fra-1による骨形成の解明とその4次元的解析Principal Investigator
- Principal Investigator
  
  高田康成, 黒田浩章
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Keio University
Tripartite relationship between osteoclasts, osteoblasts and osteocytes in bone remodeling
- Principal Investigator
  
  MATSUO Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
破骨細胞分化後期におけるc-Fosの役割の解明Principal Investigator
- Principal Investigator
  
  高田康成
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
Molecular Analysis of Initiation and Termination in Bone Formation
- Principal Investigator
  
  MATSUO Koichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
転写因子AP-1とNF-kBによる発がん制御Principal Investigator
- Principal Investigator
  
  高田康成
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Analysis of Bone Remodeling using Osteopetrotic and Osteosclerotic Mouse Models
- Principal Investigator
  
  MATSUO Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University

All 2013 2012 2011 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] AP-1の骨と免疫系における機能(20(8))2007
- Author(s)
  松尾光一、高田康成
- Publisher
  骨・関節・靱帯
- Data Source
  KAKENHI-PROJECT-19390399
[Journal Article] Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-12011
- Author(s)
  Yasunari Takada, Lionel Gresh, Aline Bozec, Eiji Ikeda, Kazunori Kamiya, Masazumi Watanabe, Koichi Kobayashi, Koichiro Asano, Yoshiaki Toyama, Erwin F. Wagner, Koichi Matsuo
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 3821-3832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390425
[Journal Article] Interstitial lung disease induced by gefitinib and toll-like receptor ligands is mediated by Fra-12011
- Author(s)
  Takada Y, Gresh L, Bozec A, Ikeda E, Kamiya K, Watanabe M, Kobayashi K, Asano K, Toyama Y, Wagner EF, Matsuo K
- Journal Title
  
  Oncogene
  
  Volume: 30 Issue: 36 Pages: 3821-32
- DOI
  10.1038/onc.2011.101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390425, KAKENHI-PROJECT-23791663
[Journal Article] Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-12011
- Author(s)
  Takada Y., et al.
- Journal Title
  
  Oncogene
  
  Volume: (inpress)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390425
[Journal Article] Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.2009
- Author(s)
  Irie, N., Takada, Y., Watanabe, Y., Matsuzaki, Y., Naruse, C., Asano, M., Iwakura, Y. Suda, T., Matsuo, K.
- Journal Title
  
  Journal of Biological Chemistry (未定)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390399
[Journal Article] Bisphosphonate therapy ameliorates hearing loss in mice lacking osteoprotegerin2009
- Author(s)
  Kanzaki S, Takada Y, Ogawa K, Matsuo K.
- Journal Title
  
  J. Bone Miner. Res. 24
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390399
[Journal Article] Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis2009
- Author(s)
  Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T, Matsuo K.
- Journal Title
  
  J. Biol. Chem.(Published on line)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390399
[Journal Article] Bisphosphonate therapy ameliorates hearing loss in mice lacking osteo protegerin.2009
- Author(s)
  Kanzaki, S., Takada, Y., Ogawa, K., Matsuo. K.
- Journal Title
  
  Journal of Bone and Mineral Research 24
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390399
[Journal Article] Signaling flux redistribution at Toll-like receptor pathway junctions2008
- Author(s)
  Selvarajoo K, Takada Y, Gohda J, Helmy M, Akira S, Tomita M, Tsuchiya M, Inoue J, Matsuo K.
- Journal Title
  
  PLoS ONE 3
  
  Pages: 3430-3430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390399
[Journal Article] c-Fos-deficient mice are susceptible to Salmonella enterica serovar Typhimurium infection2007
- Author(s)
  Maruyama K, Sano G, Ray N, Takada Y, Matsuo K.
- Journal Title
  
  Infection and immunity 75
  
  Pages: 2293-2302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012042
[Journal Article] Role of heterodimerization of Fos and Fra1 proteins in osteoclast differentiation.2007
- Author(s)
  Bakiri, L., Takada, Y., Radolf, M., Eferl, R., Yaniv, M., Wagner, E.F., Matsuo, K.
- Journal Title
  
  Bone 40
  
  Pages: 867-875
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390420
[Journal Article] Evidence that genetic deletion of the TNF receptor p60 0r p80 inhibits Fas mediated apoptosis in macrophages2007
- Author(s)
  Takada Y, et. al.
- Journal Title
  
  Biochemical pharmacology 74
  
  Pages: 1057-1064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012042
[Journal Article] Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis.2006
- Author(s)
  Zhao, C., lrie, N., Takada, Y., Shimoda, K., Miyamoto, T., Nishiwaki, T., Suda, T., Matsuo, K.
- Journal Title
  
  Cell Metabolism 4
  
  Pages: 111-121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390420
[Journal Article] Resorption of auditory ossicles and hearing loss in mice lacking osteoprotegerin.2006
- Author(s)
  Kanzaki, S., Ito, M., Takada, Y., Ogawa, K., Matsuo.K.
- Journal Title
  
  Bone 39
  
  Pages: 414-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390420
[Presentation] Impaired Bone Mineralization In Transgenic Medaka Fish Expressing Fra-1 In Osteoblasts2013
- Author(s)
  Matsumoto, T., Takada, Y., Nakamura, T., Suematsu, M., Inohaya, K., Kudo, A., Shimizu, A. and Matsuo, K.
- Organizer
  2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-24659685
[Presentation] Pericapillary Bone Formation by Mural Osteoblasts during Endochondral Ossification2013
- Author(s)
  Ichiro Takada, Nobuhito Nango, Yoshihiro Takeda, Atsushi Momose, Yoshiaki Kubota, Sho Kanzaki, Kouji Shimoda, Yasunari Takada, Latifa Bakiri, Erwin Wagner and Koichi Matsuo
- Organizer
  35th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore, Maryland, USA(Poster)
- Data Source
  KAKENHI-PROJECT-24659685
[Presentation] Impaired Bone Mineralization In Transgenic Medaka Fish Expressing Fra-1 In Osteoblasts2013
- Author(s)
  Matsumoto, T., Takada, Y., Nakamura, T., Suematsu, M., Inohaya, K., Kudo, A., Shimizu, A. and Matsuo, K
- Organizer
  2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659685
[Presentation] Transgenic expression of mouse Fra-1 in osteoblasts reduces bone mineralization in medaka fish2012
- Author(s)
  Matsumoto, T., Takada, Y., Nakamura, T., Suematsu, M., Inohaya, K., Kudo, A., Shimizu, A., and Matsuo, K
- Organizer
  小型魚類研究会(第18回)
- Place of Presentation
  京都(英語口演)
- Data Source
  KAKENHI-PROJECT-24659685
[Presentation] The osteocyte canaliculi are the basis of mineral metabolism in cortical bone studied by a multi-scan method of X-ray microscope2012
- Author(s)
  Nango, N., Kubota, S., Yashiro, W., Momose, A., Takada Y., Matsuo, K.
- Organizer
  International Workshop on X-ray and Neutron Phase Imaging with Gratings (XNPIG)
- Place of Presentation
  日本科学未来館(東京)
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] The osteocyte canaliculi are the basis of mineral metabolism in cortical bone studied by a multi-scan method of X-ray microscope2012
- Author(s)
  Nango, N., Kubota, S., Yashiro, W., Momose, A., Takada Y., Matsuo, K
- Organizer
  International Workshop on X-ray and Neutron Phase Imaging with Gratings(XNPIG)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Transgenic expression of mouse Fra-1 in osteoblasts reduces bone mineralization in medaka fish.2012
- Author(s)
  Matsumoto, T., Takada, Y., Nakamura, T., Suematsu, M., Inohaya, K., Kudo, A., Shimizu, A., and Matsuo, K.
- Organizer
  第18回　小型魚類研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659685
[Presentation] 3D visualization of osteocyte lacunae in the entire long bone2011
- Author(s)
  Takeda, Y., Takada, Y., Omote, K., Matsuo, K
- Organizer
  33^<rd> Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Osteoclasts affect hearing function and auditory ossicles2011
- Author(s)
  Kanzaki, S., Takada, Y., Ogawa, K., Matsuo, K
- Organizer
  10th international symposium : Recent Advances in Otitis Media
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] 3D visualization of osteocyte lacunae in the entire long bone2011
- Author(s)
  Takeda, Y., Takada, Y., Omote, K., Matsuo, K.
- Organizer
  33rd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Osteoprotegerin prevents infection-induced bone loss2011
- Author(s)
  Takada, Y., Matsuo, K
- Organizer
  33rd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Osteoprotegerinによる感染性骨破壊の抑制2011
- Author(s)
  高田康成、松尾光一
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Osteoclast-dependent canalicular formation in cortical bone that mediates bone remodeling2011
- Author(s)
  Nango, N., Kubota, S., Yashiro, W., Momose, A., Takada, Y., Matsuo, K
- Organizer
  33^<rd> Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Osteoclast-dependent canalicular formation in cortical bone that mediates bone remodeling2011
- Author(s)
  Nango, N., Kubota, S., Yashiro, W., Momose, A., Takada, Y., Matsuo, K.
- Organizer
  33rd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Osteoprotegerinによる感染性骨破壊の抑制2011
- Author(s)
  高田康成、松尾光一
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21390425
[Presentation] Late expression of c-Fos during osteoclast differentiation determines osteoclast survival and bone mass2009
- Author(s)
  Takada Y, Irie N, Grech L, Nakamura T, Kato S, Wagner EF, Matsuo K
- Organizer
  2^<nd> Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society
- Place of Presentation
  Sydney (Australia)
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-20659237
[Presentation] Late expression of c-Fos during osteoclast differentiation determines osteoclast survival and bone mass2009
- Author(s)
  Takada, Y., Irie, N., Grech, L., Nakamura, T., Kato, S., Wagner, E. F., Matsuo, K.
- Organizer
  2nd Joint Meeting of the International Bone & Mineral Society and the Australian and New Zealand Bone & Mineral Society
- Place of Presentation
  Sydney, Austria
- Data Source
  KAKENHI-PROJECT-19390399
[Presentation] Bisphosphonate therapy ameliorates bone resorption and hearing loss in mice lacking osteoprotegerin2008
- Author(s)
  Kanzaki, S., Takada, Y., Ogawa, K., Matsuo, K.
- Organizer
  8th International Conference on Cholesteatoma & Ear Surgery
- Place of Presentation
  Antalya, Turkey
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-19390399
[Presentation] ephrinA2-EphA2両方向性シグナルによる骨リモデリング開始期の制御2008
- Author(s)
  入江奈緒子, 高田康成, 松尾光
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390399
[Presentation] 破骨細胞分化の際のc-Fos第2次発現の意義と役割2008
- Author(s)
  高田康成, 中村貴, 加藤茂明, 松尾光一
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20659237

1. MATSUO Koichi (40229422)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
2. YAMAGUCHI Toru (50338092)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TOYAMA Yoshiaki (40129549)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 池田栄二 (30232177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 黒田浩章 (20365274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

TAKADA Yasunari 高田 康成

Research Projects

Research Products

Co-Researchers

In search for shared regulatory mechanisims of bone mineralization in vertebrates

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子Fra-1による骨形成の解明とその4次元的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tripartite relationship between osteoclasts, osteoblasts and osteocytes in bone remodeling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

破骨細胞分化後期におけるc-Fosの役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Analysis of Initiation and Termination in Bone Formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子AP-1とNF-kBによる発がん制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Bone Remodeling using Osteopetrotic and Osteosclerotic Mouse Models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] AP-1の骨と免疫系における機能(20(8))2007

Author(s)

Publisher

Data Source

[Journal Article] Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-12011

Author(s)

Journal Title

Data Source

[Journal Article] Interstitial lung disease induced by gefitinib and toll-like receptor ligands is mediated by Fra-12011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-12011

Author(s)

Journal Title

Data Source

[Journal Article] Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Bisphosphonate therapy ameliorates hearing loss in mice lacking osteoprotegerin2009

Author(s)

Journal Title

Data Source

[Journal Article] Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis2009

Author(s)

Journal Title

Data Source

[Journal Article] Bisphosphonate therapy ameliorates hearing loss in mice lacking osteo protegerin.2009

Author(s)

Journal Title

Data Source

[Journal Article] Signaling flux redistribution at Toll-like receptor pathway junctions2008

TAKADA Yasunari 高田康成