SHIMIZU MAKOTO 清水誠

… Alternative Names

SHIMIZU Makoto 清水誠

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Researcher Number	40409008
Affiliation (Current)	2025: お茶の水女子大学, 基幹研究院, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: お茶の水女子大学, 基幹研究院, 准教授 2019 – 2022: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授 2016 – 2018: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2012 – 2015: 東京大学, 農学生命科学研究科, 助教 2014: 東京大学, 大学院農学生命科学研究科, 助教 2012: 東京大学, 大学院・農学生命科学研究科, 助教 2011: 東京大学, 大学院農学生命科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Food science / Medium-sized Section 38:Agricultural chemistry and related fields / Agricultural chemistry and related fields / Integrated Nutrition Science Except Principal Investigator Food science / Medium-sized Section 38:Agricultural chemistry and related fields
Keywords	Principal Investigator 老化 / 骨格筋 / FGF21 / 抗老化 / 食品成分 / 機能性食品成分 / ATF4 / セノリシス / RNAiスクリーニング / ミトコンドリアダイナミクス … More / ミトコンドリア / アンチエイジング / 転写因子 / PPARg / 脂肪肝 / タンパク質修飾 / 酸化ストレス / センサータンパク質 / 筋肥大 / C2C12 / 電気刺激 / 酸化修飾 / 小胞体ストレス / FGF19 / FGF15 / 糖尿病 / 食品 / GPCR / 機能性食品 / 肥満 / 胆汁酸 / TGR5 … More Except Principal Investigator コレステロール / ヒトiPS細胞 / 小腸オルガノイド / Perilipin / SREBP / 脂肪滴形成 / トリグリセリド / メチル化 / 脂肪酸合成 / 転写因子 / 果糖 / スプライシング / 脂肪肝 / ChREBP / SREBP-1 / 抗肥満 / TGR5 / CREB / 食品成分 / Gタンパク質共役受容体 / 食品機能 Less

Study of anti-aging food factors which activate senolysisPrincipal Investigator
- Principal Investigator
  
  清水誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ochanomizu University
ヒトiPS細胞由来小腸オルガノイドを用いた次世代食品栄養学・食品科学研究の開拓
- Principal Investigator
  
  佐藤隆一郎
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
Analysis of sensor proteins which regulates mitochondrial dynamics in skeletal musclePrincipal Investigator
- Principal Investigator
  
  Shimizu Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Ochanomizu University
  The University of Tokyo
Identification and molecular mechanism of anti-aging food factors which activate an anti-obese hormonePrincipal Investigator
- Principal Investigator
  
  Shimizu Makoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Analysis of sensor proteins which receive signals of muscle contractionPrincipal Investigator
- Principal Investigator
  
  Shimizu Makoto
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
Study of novel mechanisms of transcriptional regulation and lipid metabolism by FGF21Principal Investigator
- Principal Investigator
  
  Shimizu Makoto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Functional study of anti-obese, anti-diebetes, anti-oxidative transcription factor and identification of functional food factor which activate this transcription factorPrincipal Investigator
- Principal Investigator
  
  Shimizu Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  The University of Tokyo
Study on hepatic liver accumulation and SREBP-1 activation, and function of food factors
- Principal Investigator
  
  SATO Ryuichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Study on functional foods that associate with G protein-coupled receptors
- Principal Investigator
  
  SATO Ryuichiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Functional analysis of novel food factors which activate anti-obese receptor for bile acidsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Makoto
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2018 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Drug cytotoxicity screening using human intestinal organoids propagated with extensive cost-reduction strategies2023
- Author(s)
  Takahashi Yu、Inoue Yu、Sato Shintaro、Okabe Takayoshi、Kojima Hirotatsu、Kiyono Hiroshi、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 5407-5407
- DOI
  10.1038/s41598-023-32438-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-23K26849, KAKENHI-PROJECT-23K27420
[Journal Article] Hydroxylation site?specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR2023
- Author(s)
  Saito Hodaka、Tachiura Wakana、Nishimura Mizuki、Shimizu Makoto、Sato Ryuichiro、Yamauchi Yoshio
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 1 Pages: 102733-102733
- DOI
  10.1016/j.jbc.2022.102733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K21200, KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-23K26849
[Journal Article] Establishment of a cell culture platform for human liver organoids and its application for lipid metabolism research2023
- Author(s)
  Kuboyama‐Sasaki Ayane、Takahashi Yu、Xia Chen、Hiro Kahori、Kobayashi Tsuyoshi、Ohdan Hideki、Shimizu Makoto、Yamauchi Yoshio、Kiyono Hiroshi、Sato Ryuichiro
- Journal Title
  
  Biotechnology Journal
  
  Volume: 19 Issue: 1 Pages: 5407-5407
- DOI
  10.1002/biot.202300365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-23K05070, KAKENHI-PROJECT-20H00408
[Journal Article] Nobiletin enhances plasma Interleukin‐6 and C‐X‐C motif chemokine ligand 1 levels that are increased by treadmill running2022
- Author(s)
  Suzuki Toshihide、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Food Science & Nutrition
  
  Volume: 10 Issue: 7 Pages: 2360-2369
- DOI
  10.1002/fsn3.2844
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-20H00408
[Journal Article] Endocrine Fibroblast Growth Factors in Relation to Stress Signaling2022
- Author(s)
  Shimizu Makoto、Sato Ryuichiro
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 3 Pages: 505-505
- DOI
  10.3390/cells11030505
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066
[Journal Article] Lactic acid bacteria?derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids2022
- Author(s)
  Noguchi Makoto、Shimizu Makoto、Lu Peng、Takahashi Yu、Yamauchi Yoshio、Sato Shintaro、Kiyono Hiroshi、Kishino Shigenobu、Ogawa Jun、Nagata Koji、Sato Ryuichiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 11 Pages: 102534-102534
- DOI
  10.1016/j.jbc.2022.102534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-18H05280
[Journal Article] Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies2022
- Author(s)
  Takahashi Yu、Noguchi Makoto、Inoue Yu、Sato Shintaro、Shimizu Makoto、Kojima Hirotatsu、Okabe Takayoshi、Kiyono Hiroshi、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 7 Pages: 104542-104542
- DOI
  10.1016/j.isci.2022.104542
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-18H05280
[Journal Article] Sesamin and Hepatic Metabolites Derived from Sesamin and Episesamin Antagonize Farnesoid X Receptor and Reduce the Expression of Gluconeogenesis-Related Genes2022
- Author(s)
  SASAKI Takashi、OKUDA Mako、HONG Tzu-Wen、WATANABE Yuichi、TAKAHASHI Yu、SHIMIZU Makoto、YAMAUCHI Yoshio、SATO Ryuichiro
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 68 Issue: 1 Pages: 55-64
- DOI
  10.3177/jnsv.68.55
- NAID
  130008164780
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2022-02-28
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066
[Journal Article] Skeletal muscle releases extracellular vesicles with distinct protein and microRNA signatures that function in the muscle microenvironment2022
- Author(s)
  Watanabe Sho、Sudo Yuri、Makino Takumi、Kimura Satoshi、Tomita Kenji、Noguchi Makoto、Sakurai Hidetoshi、Shimizu Makoto、Takahashi Yu、Sato Ryuichiro、Yamauchi Yoshio
- Journal Title
  
  PNAS Nexus
  
  Volume: 1 Issue: 4
- DOI
  10.1093/pnasnexus/pgac173
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-20J22415
[Journal Article] Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes2022
- Author(s)
  Honda Mikako、Makino Takumi、Zhao Xiaolin、Matsuto Mariko、Sakurai Hidetoshi、Takahashi Yu、Shimizu Makoto、Sato Ryuichiro、Yamauchi Yoshio
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 323 Issue: 5 Pages: C1402-C1409
- DOI
  10.1152/ajpcell.00341.2022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19066
[Journal Article] Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK?eIF2α?ATF4 axis2021
- Author(s)
  Watanabe Yuichi、Sasaki Takashi、Miyoshi Shoko、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 297 Issue: 2 Pages: 100989-100989
- DOI
  10.1016/j.jbc.2021.100989
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066, KAKENHI-PROJECT-19K15764
[Journal Article] Orange peel extract reduces the inflammatory state of skeletal muscle after downhill running via an increase in IL-1RA2021
- Author(s)
  Suzuki Toshihide、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 6 Pages: 1506-1513
- DOI
  10.1093/bbb/zbab049
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066
[Journal Article] Maslinic acid activates mTORC1 and human TGR5 and induces skeletal muscle hypertrophy2021
- Author(s)
  Murata Shotaro、Sasaki Takashi、Yamauchi Yuki、Shimizu Makoto、Sato Ryuichiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 11 Pages: 2311-2321
- DOI
  10.1093/bbb/zbab151
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066
[Journal Article] Comparison of gene expression and activation of transcription factors in organoid-derived monolayer intestinal epithelial cells and organoids2021
- Author(s)
  Takahashi Yu、Inoue Yu、Kuze Keitaro、Sato Shintaro、Shimizu Makoto、Kiyono Hiroshi、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 10 Pages: 2137-2144
- DOI
  10.1093/bbb/zbab136
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05928, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-21K19066
[Journal Article] Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice2021
- Author(s)
  Sasaki Takashi、Watanabe Yuichi、Kuboyama Ayane、Oikawa Akira、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100131-100131
- DOI
  10.1074/jbc.ra120.016203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15786, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-19J22409, KAKENHI-PROJECT-17K19219, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-21K19066
[Journal Article] Functional effect of nobiletin as a food-derived allosteric modulator of mouse CRFR2β in skeletal muscle2020
- Author(s)
  Chikazawa Miho、Moriwaki Yoshitaka、Uramoto Mari、Yamauchi Yoshio、Shimizu Makoto、Shimizu Kentaro、Sato Ryuichiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 2 Pages: 328-334
- DOI
  10.1016/j.bbrc.2020.03.189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-17K19219
[Journal Article] Polymethoxyflavones in orange peel extract prevent skeletal muscle damage induced by eccentric exercise in rats2020
- Author(s)
  Suzuki Toshihide、Shimizu Makoto、Yamauchi Yoshio、Sato Ryuichiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 2 Pages: 440-446
- DOI
  10.1093/bbb/zbaa036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02906, KAKENHI-PROJECT-19H02908, KAKENHI-PROJECT-17K19219, KAKENHI-PROJECT-20H00408
[Journal Article] Searching for novel ATF4 target genes in human hepatoma cells by microarray analysis.2016
- Author(s)
  Maruyama R., Shimizu M., Ishijima T., Nakai Y., Inoue J., and Sato R.
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: in press Issue: 6 Pages: 1-6
- DOI
  10.1080/09168451.2016.1146072
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J10497, KAKENHI-PROJECT-25504003
[Journal Article] Selective regulation of FGF19 and FGF21 expression by cellular and nutritional stress2015
- Author(s)
  Makoto Shimizu, Hitomi Morimoto, Ryuto Maruyama, Jun Inoue, and Ryuichiro Sato
- Journal Title
  
  J Nutr Sci Vitaminol
  
  Volume: 61 Pages: 1-10
- NAID
  130005074124
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24248023
[Journal Article] Quercetin represses apolipoprotein B expression by inhibiting the transcriptional activity of C/EBPβ2015
- Author(s)
  Makoto Shimizu, Li Juan, Jun Inoue, and Ryuichiro Sato
- Journal Title
  
  PLoS One
  
  Volume: 10 Pages: 1-12
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24248023
[Journal Article] The role of AMPK and PPARγ1 in exercise-induced lipoprotein lipase in skeletal muscle.2014
- Author(s)
  Sasaki, T., Nakata, R., Inoue, H., Shimizu, M., Inoue, J., and　Sato, R.
- Journal Title
  
  Am. J. Physiol. Endocrinol. Metab.
  
  Volume: 306 Issue: 9 Pages: 1085-1092
- DOI
  10.1152/ajpendo.00691.2013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24248023
[Journal Article] Anti-obesity and anti-hyperglycemic effects2011
- Author(s)
  Ono, Inoue, Hashidume, Shimizu, Sato
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 410 Issue: 3 Pages: 677-681
- DOI
  10.1016/j.bbrc.2011.06.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658109, KAKENHI-PROJECT-23780127
[Presentation] 骨格筋恒常性の理解を目的とした線維芽細胞増殖因子に関する研究2023
- Author(s)
  清水　誠
- Organizer
  3D培養筋研究情報交換会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26849
[Presentation] 乳酸菌由来γリノレン酸代謝産物γKetoD、γHYDはヒト小腸オルガノイドの脂質代謝を改善するPPARδリガンドである2023
- Author(s)
  清水誠
- Organizer
  日本農芸化学会関東支部2023年度例会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26849
[Presentation] 脂肪肝応答因子による遺伝子発現制御機構2023
- Author(s)
  清水　誠
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-23K26849
[Presentation] 腸内細菌由来脂肪酸による小腸のエネルギー代謝制御2023
- Author(s)
  清水　誠
- Organizer
  第5 回脂質駆動学術産業創生研究部会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 骨格筋恒常性の理解を目的とした線維芽細胞増殖因子に関する研究2023
- Author(s)
  清水　誠
- Organizer
  3D培養筋研究情報交換会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 脂肪肝応答因子による遺伝子発現制御機構2023
- Author(s)
  清水　誠
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 腸内細菌由来脂肪酸代謝産物によるヒト小腸オルガノイドのエネルギー代謝制御2023
- Author(s)
  清水誠
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K26849
[Presentation] 乳酸菌由来γリノレン酸代謝産物γKetoD、γHYDはヒト小腸オルガノイドの脂質代謝を改善するPPARδリガンドである2023
- Author(s)
  清水　誠
- Organizer
  日本農芸化学会関東支部2023年度例会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 腸内細菌由来脂肪酸による小腸のエネルギー代謝制御2023
- Author(s)
  清水　誠
- Organizer
  第5 回脂質駆動学術産業創生研究部会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26849
[Presentation] 腸内細菌由来脂肪酸代謝産物によるヒト小腸オルガノイドのエネルギー代謝制御2023
- Author(s)
  清水　誠
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 大豆タンパク質βコングリシニンによる代謝改善効果2022
- Author(s)
  清水誠
- Organizer
  第42回日本肥満学会・第39回日本肥満症治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 大豆タンパク質βコングリシニンによる代謝改善効果2022
- Author(s)
  清水誠
- Organizer
  第42回日本肥満学会・第39回日本肥満症治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02906
[Presentation] フルクトース誘導性脂肪肝におけるセリン生合成及び代謝経路の制御機構2022
- Author(s)
  清水誠、鄭力榕、山内祥生、及川彰、佐藤隆一郎
- Organizer
  日本アミノ酸学会第16回学術大会
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] Identification of a food-derived molecule which induces the anti-obese hormone FGF212022
- Author(s)
  Makoto SHIMIZU, Yoshio YAMAUCHI, and Ryuichiro SATO
- Organizer
  22nd IUNS-ICN, Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 低タンパク質誘導性脂肪肝を制御する新たな転写因子の同定2021
- Author(s)
  清水誠、鄭力榕、不野歩美、梅村真理子、高橋勇二、山内祥生、佐藤隆一郎
- Organizer
  日本アミノ酸学会第 15 回学術大会
- Data Source
  KAKENHI-PROJECT-19H02906
[Presentation] 低タンパク質誘導性脂肪肝を制御する新たな転写因子の同定2021
- Author(s)
  清水誠、鄭力榕、不野歩美、梅村真理子、高橋勇二、山内祥生、佐藤隆一郎
- Organizer
  日本アミノ酸学会第15回学術大会
- Data Source
  KAKENHI-PROJECT-21K19066
[Presentation] 核内受容体LXRによる骨格筋機能制御2020
- Author(s)
  清水誠、小野敦子、近澤未歩、山内祥生、佐藤隆一郎1
- Organizer
  日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-19H02906
[Presentation] 核内受容体LXRによる骨格筋機能制御2020
- Author(s)
  清水誠、小野敦子、近澤未歩、山内祥生、佐藤隆一郎
- Organizer
  日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K19219
[Presentation] 非アルコール性脂肪肝を制御する新たな転写因子の同定2020
- Author(s)
  清水誠、不野歩美、梅村真理子、高橋勇二、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-19H02906
[Presentation] 非アルコール性脂肪肝を制御する新たな転写因子の同定2020
- Author(s)
  清水誠、不野歩美、梅村真理子、高橋勇二、山内祥生、佐藤隆一郎
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-17K19219
[Presentation] 抗肥満ホルモンFGF21の新規発現制御因子の同定2018
- Author(s)
  清水誠、梅村真理子、高橋勇二、井上順、佐藤隆一郎
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16H06195
[Presentation] ATF4-FGF19/21経路の発見と活性化食品成分の解析2016
- Author(s)
  清水誠
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  武庫川女子大学（神戸）
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-25504003
[Presentation] ChREBPβの組織における発現分布と機能の解析2014
- Author(s)
  井上聖哉、井上順、Shimizu Makoto，佐藤隆一郎
- Organizer
  日本農芸化学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24248023
[Presentation] 胆汁酸受容体TGR5の各種リガンド結合能の解析2013
- Author(s)
  碇菜穂、清水誠、石黒正路、井上順、佐藤隆一郎
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23658109
[Presentation] SREBP活性を抑制する食品成分の探索・解析2013
- Author(s)
  宮田　慎吾、井上　順、Shimizu Makoto、佐藤　隆一郎
- Organizer
  日本栄養・食糧学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24248023
[Presentation] TGR5を活性化する新規化合物の機能解析2013
- Author(s)
  清水誠
- Organizer
  第67回日本栄養・食糧学会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-23780127
[Presentation] 柑橘由来成分ノミリンの胆汁酸受容体TGR5を介した抗肥満作用2012
- Author(s)
  井上順、小野絵里、橋詰力、清水誠、佐藤隆一郎
- Organizer
  第66回日本栄養・食糧学会大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23658109
[Presentation] TGR5を活性化する新規化合物の機能解析
- Author(s)
  清水　誠
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23780127
[Presentation] SREBP活性を抑制する食品成分の探索・機能解析
- Author(s)
  宮田慎吾、井上　順、清水　誠、佐藤隆一郎
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  札幌
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-24248023
[Presentation] ＣｈＲＥBＰアイソフォームを介した糖・脂質代謝関連遺伝子の転写制御機構
- Author(s)
  井上　聖哉、井上　順、清水　誠、佐藤　隆一郎
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24248023

1. SATO Ryuichiro (50187259)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
2. 高橋裕 (30835377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 齋藤穂高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 佐々木崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMIZU MAKOTO 清水 誠

SHIMIZU Makoto 清水 誠

Research Projects

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Study of anti-aging food factors which activate senolysisPrincipal Investigator

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ヒトiPS細胞由来小腸オルガノイドを用いた次世代食品栄養学・食品科学研究の開拓

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Analysis of sensor proteins which regulates mitochondrial dynamics in skeletal musclePrincipal Investigator

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Identification and molecular mechanism of anti-aging food factors which activate an anti-obese hormonePrincipal Investigator

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Analysis of sensor proteins which receive signals of muscle contractionPrincipal Investigator

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Study of novel mechanisms of transcriptional regulation and lipid metabolism by FGF21Principal Investigator

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Functional study of anti-obese, anti-diebetes, anti-oxidative transcription factor and identification of functional food factor which activate this transcription factorPrincipal Investigator

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Study on hepatic liver accumulation and SREBP-1 activation, and function of food factors

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Study on functional foods that associate with G protein-coupled receptors

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Functional analysis of novel food factors which activate anti-obese receptor for bile acidsPrincipal Investigator

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[Journal Article] Drug cytotoxicity screening using human intestinal organoids propagated with extensive cost-reduction strategies2023

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[Journal Article] Hydroxylation site?specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR2023

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[Journal Article] Establishment of a cell culture platform for human liver organoids and its application for lipid metabolism research2023

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SHIMIZU MAKOTO 清水誠

SHIMIZU Makoto 清水誠