Nagasu Hajime 長洲一

Researcher Number	40412176
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 川崎医科大学, 医学部, 准教授 2016 – 2019: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine Except Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine / Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 慢性腎臓病 / 糸球体上皮細胞 / 糖尿病性腎臓病 / インフラマソーム / kidney / 内皮機能障害 / Inflammasome / TRPC / 加齢 / 老化 … More / カルシウム / sGC / 糖尿病性腎症 / podocyte / inflammasome / mitochondoria / 上皮細胞 / Nrf2 / マクロファージ / 慢性炎症 / 腎臓病 … More Except Principal Investigator 慢性腎臓病 / 線維化 / 内皮障害 / 酸化ストレス / NO / TRPC / ポドサイト / 内皮機能障害 / 炎症 / Wnt / インフラマソーム / 慢性炎症 / マクロファージ / sGC / 細胞老化 / ストレスDNA損傷 / PKG / 活性酸素種 / ドラッグリポジショニング / リアルワールドエビデンス / 人工知能 / リアルワールドデータ / 深層学習 / Calcium dynamics / Oxidative stress / GFR / Keap1/Nrf2 / Keap1-Nrf2 / 細胞内カルシウム / GFR制御 / Keap1-Nrf2機構 / 内皮細胞 / 繊維化 / 血行動態変化 / 内皮/上皮連関 / 老化 / Keap-1/Nrf2 / Keap1/Nrf-2 / NLRP3 inflammasome / Wnt/βーcatenine / 自己反応性リンパ球 / 自己抗体 / Imiquimod誘発SLEモデル / Faslprマウス / SLEモデルマウス / 樹状細胞 / Fas-lprマウス / Cherubism / 全身性エリテマトーデス / SH3BP2 / 多光子レーザー顕微鏡 / in vivo imaging / アルブミン尿 / 一酸化窒素 / 認知機能障害 / 加齢 / 酸化ストレアス / Nrf2 / 血管内皮障害 / 腸管 / 腎臓病 / 細菌 / 腸管透過性 / 尿毒素 / Rスポンディン / 腎不全 / ディフェンシン / 腸管バリア / 腸内細菌 / 慢性腎不全 Less

Unraveling the pathophysiology of kidney disease and developing treatments based on the endothelial/epithelial pathomechanical linkage and ROS/NO imbalance.
- Principal Investigator
  
  柏原直樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
Elucidating the Relationship between Stress DNA Damage and Exacerbation of Kidney Disease
- Principal Investigator
  
  岸誠司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
血管内皮細胞による免疫調整機構と腎疾患進展における役割の解明
- Principal Investigator
  
  佐々木環
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
老化関連腎障害におけるTRPC依存的Ca動態による糸球体内微小炎症の制御機構解明Principal Investigator
- Principal Investigator
  
  長洲一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
Elucidation of the role of the Keap1-Nrf2 mechanism in the regulation of glomerular filtration rate (GFR)
- Principal Investigator
  
  城所研吾
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
人間と人工知能の共創的な知を用いたドラッグリポジショニングによる腎臓病治療法開発
- Principal Investigator
  
  矢野裕一朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shiga University of Medical Science
Development of a comprehensive spatio-temporal understanding of the pathogenesis and progression of chronic kidney disease and the development of therapeutic strategies
- Principal Investigator
  
  Kashihara Naoki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
sGC activation on the interaction between glomerular endothelial cells and podcyte.Principal Investigator
- Principal Investigator
  
  Nagasu Hajime
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
The role of SH3BP2 in the pathogenesis of systemic lupus eryhematosus
- Principal Investigator
  
  Mukai Tomoyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kawasaki Medical School
Inflammasome activation in podocyte of diabetic kidney diseasesPrincipal Investigator
- Principal Investigator
  
  Nagasu Hajime
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
Implications of endothelial injuries and endothelial/epithelial interactions as pathogenetic mechanisms underlying progression of chronic kidney disease and its therapeutic application.
- Principal Investigator
  
  Kashihara Naoki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kawasaki Medical School
Analysis of intestinal microbiota and barrier function in chronic renal failure and therapeutic strategy
- Principal Investigator
  
  Satoh Minoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School
The mechanism of inflammasome activation associated chronic inflammation on CKD.Principal Investigator
- Principal Investigator
  
  Nagasu Hajime
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School
Investigation of molecular mechanisms of endothelial dysfunction underlying CKD and aging kidney
- Principal Investigator
  
  Kashihara Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Other

[Journal Article] Oxidative stress and the role of redox signalling in chronic kidney disease.2024
- Author(s)
  Kishi S, Nagasu H, Kidokoro K, Kashihara N.
- Journal Title
  
  Nat Rev Nephrol.
  
  Volume: 20 Issue: 2 Pages: 101-119
- DOI
  10.1038/s41581-023-00775-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02937
[Journal Article] Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis2023
- Author(s)
  Kadoya Hiroyuki、Hirano Akira、Umeno Reina、Kajimoto Eriko、Iwakura Tsukasa、Kondo Megumi、Wada Yoshihisa、Kidokoro Kengo、Kishi Seiji、Nagasu Hajime、Sasaki Tamaki、Taniguchi Shun’ichiro、Takahashi Masafumi、Kashihara Naoki
- Journal Title
  
  The FASEB Journal
  
  Volume: 37 Issue: 9
- DOI
  10.1096/fj.202201777rrr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06613, KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-21K16199, KAKENHI-PROJECT-21H02937
[Journal Article] Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway.2023
- Author(s)
  Kidokoro K, Kadoya H, Cherney DZI, Kondo M, Wada Y, Umeno R, Kishi S, Nagasu H, Nagai K, Suzuki T, Sasaki T, Yamamoto M, Kanwar YS, Kashihara N.
- Journal Title
  
  Kidney360.
  
  Volume: 4 Issue: 10 Pages: 1454-1466
- DOI
  10.34067/kid.0000000000000171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02937
[Journal Article] Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank2022
- Author(s)
  Sugawara Yuka、Hirakawa Yosuke、Nagasu Hajime、Narita Akira、Katayama Akihiro、Wada Jun、Shimizu Miho、Wada Takashi、Kitamura Hiromasa、Nakano Toshiaki、Yokoi Hideki、Yanagita Motoko、Goto Shin、Narita Ichiei、Koshiba Seizo、Tamiya Gen、Nangaku Masaomi、Yamamoto Masayuki、Kashihara Naoki
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 2 Pages: 55-64
- DOI
  10.1038/s10038-022-01094-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10439, KAKENHI-PROJECT-19H03674, KAKENHI-PROJECT-21H02937, KAKENHI-PROJECT-17K07298, KAKENHI-PUBLICLY-21H00179
[Journal Article] Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation2021
- Author(s)
  Wada Y、Umeno R、Nagasu H、Kondo M、Tokuyama A、Kadoya H、Kidokoro K、Taniguchi S、Takahashi M、Sasaki T、Kashihara N
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 17 Pages: 9269-9269
- DOI
  10.3390/ijms22179269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02937, KAKENHI-PROJECT-20K08602, KAKENHI-PROJECT-21K06613
[Journal Article] Dipeptidyl peptidase-4 inhibitor linagliptin reduces urinary albumin excretion through the protection of glomerular endothelial function2021
- Author(s)
  Kondo M, Kidokoro K, Uchida A, Kadoya H, Umeno R, Tokuyama A, Wada Y, Nagasu H, Kanda E, Sasaki T, Kashihara N
- Journal Title
  
  Kawasaki Medical Journal
  
  Volume: 47 Pages: 131-141
- DOI
  10.11482/KMJ-E202147131
- ISSN
  0385-0234, 2434-3404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02937
[Journal Article] Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease2020
- Author(s)
  Itano Seiji、Yano Yuichiro、Nagasu Hajime、Tomiyama Hirofumi、Kanegae Hiroshi、Makino Hirofumi、Higashi Yukihito、Kobayashi Yusuke、Sogawa Yuji、Satoh Minoru、Suzuki Kenji、Townsend Raymond R、Budoff Matthew、Bakris George、Kashihara Naoki
- Journal Title
  
  American Journal of Hypertension
  
  Volume: 33 Issue: 11 Pages: 1003-1010
- DOI
  10.1093/ajh/hpaa097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02828, KAKENHI-PROJECT-18K09758
[Journal Article] Klotho is a novel therapeutic target in peritoneal fibrosis via Wnt signaling inhibition.2020
- Author(s)
  Kadoya H, Satoh M, Nishi Y, Kondo M, Wada Y, Sogawa Y, Kidokoro K, Nagasu H, Sasaki T, Kashihara N.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: - Issue: 5 Pages: 773-781
- DOI
  10.1093/ndt/gfz298
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02828
[Journal Article] Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.2020
- Author(s)
  2.Maria Gerasimenko; Olga Lopatina; Anna A. Shabalova; Stanislav M. Cherepanov; Alla B. Salmina; Shigeru Yokoyama; Hisanori Goto; Hiroshi Okamoto; Yasuhiko Yamamoto; Katsuhiko Ishihara; Haruhiro Higashida.
- Journal Title
  
  PLoS One
  
  Volume: 15(12) Issue: 8 Pages: 4169-4169
- DOI
  10.3390/ijms22084169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-18K08398, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-21K08484
[Journal Article] Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice2019
- Author(s)
  Nagasu Akiko、Mukai Tomoyuki、Iseki Masanori、Kawahara Kyoko、Tsuji Shoko、Nagasu Hajime、Ueki Yasuyoshi、Ishihara Katsuhiko、Kashihara Naoki、Morita Yoshitaka
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 5 Pages: 402-402
- DOI
  10.3390/cells8050402
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-18H02828
[Journal Article] Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice using In Vivo Imaging.2019
- Author(s)
  1.Kidokoro K, Cherney DZI, Bozovic A, Nagasu H, Satoh M, Kanda E, Sasaki T, Kashihara N
- Journal Title
  
  Circulation
  
  Volume: in press Issue: 4 Pages: 303-315
- DOI
  10.1161/circulationaha.118.037418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Journal Article] Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function2019
- Author(s)
  Nagasu Hajime、Sogawa Yuji、Kidokoro Kengo、Itano Seiji、Yamamoto Toshiya、Satoh Minoru、Sasaki Tamaki、Suzuki Takafumi、Yamamoto Masayuki、Wigley W. Christian、Proksch Joel W.、Meyer Colin J.、Kashihara Naoki
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 11 Pages: 12253-12263
- DOI
  10.1096/fj.201900217r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02828, KAKENHI-PROJECT-18K19417
[Journal Article] Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis.2018
- Author(s)
  Fujita S, Mukai T, Mito T, Kodama S, Nagasu A, Kittaka M, Sone T, Ueki Y, Morita Y.
- Journal Title
  
  Bone
  
  Volume: 106 Pages: 156-166
- DOI
  10.1016/j.bone.2017.10.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09540, KAKENHI-PROJECT-18K08398
[Journal Article] The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice2018
- Author(s)
  Yuji Sogawa, Hajime Nagasu , Seiji Itano, Kengo Kidokoro, Shun’ichiro Taniguchi, Masafumi Takahashi, Hiroyuki Kadoya, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara
- Journal Title
  
  ProS One
  
  Volume: 13 Issue: 10 Pages: e0203823-e0203823
- DOI
  10.1371/journal.pone.0203823
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18H02828
[Journal Article] 5-aminolevulinic acid exerts renoprotective effect via Nrf2 activation in murine rhabdomyolysis-induced acute kidney injury.2018
- Author(s)
  Uchida A, Kidokoro K, Sogawa Y, Itano S, Nagasu H, Satoh M, Sasaki T, Kashihara N
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: - Issue: 1 Pages: 28-38
- DOI
  10.1111/nep.13189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04838
[Journal Article] 降圧薬治療　レニン・アンジオテンシン系阻害薬2017
- Author(s)
  柏原直樹、長洲一、桑原篤憲
- Journal Title
  
  臨牀と研究
  
  Volume: 94 Pages: 33-38
- Data Source
  KAKENHI-PROJECT-15H04838
[Journal Article] 血圧コントロールとRA系阻害薬の臨床的意義2017
- Author(s)
  柏原直樹、庵谷千恵子、長洲一
- Journal Title
  
  カレントテラピー
  
  Volume: 35 Pages: 48-53
- Data Source
  KAKENHI-PROJECT-15H04838
[Journal Article] Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice.2017
- Author(s)
  Sogawa Y, Nagasu H, Iwae S, Ihoriya C, Itano S, Uchida A, Kidokoro K, Taniguchi S, Takahashi M, Satoh M, Sasaki T, Suzuki T, Yamamoto M, Horng T and Kashihara N.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 8801-8801
- DOI
  10.1038/s41598-017-08054-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15590, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04838, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19501
[Journal Article] Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice.2016
- Author(s)
  Nagasu H, Satoh M, Kiyokage E, Kidokoro K, Toida K, Channon KM, Kanwar YS, Sasaki T, Kashihara N.
- Journal Title
  
  Lab Invest
  
  Volume: 96 Issue: 1 Pages: 25-36
- DOI
  10.1038/labinvest.2015.128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06748, KAKENHI-PROJECT-15H04838
[Journal Article] 慢性腎臓病（CKD)と急性腎障害（AKI)　循環器薬物療法を行う際の投薬計画2016
- Author(s)
  長洲一、城所研吾、柏原直樹
- Journal Title
  
  医学のあゆみ
  
  Volume: 259 Pages: 1353-1358
- Data Source
  KAKENHI-PROJECT-15H04838
[Journal Article] 腎代替療法とフリーラジカル　慢性腎臓病（CKD)2016
- Author(s)
  柏原直樹、長洲一、城所研吾、佐藤稔
- Journal Title
  
  腎と透析
  
  Volume: 81 Pages: 1007-1013
- Data Source
  KAKENHI-PROJECT-15H04838
[Journal Article] Deficiency of endothelial nitric oxide signaling pathway exacerbates peritoneal fibrosis in mice2015
- Author(s)
  Kadoya H, Satoh M, Nagasu H, Sasaki T, Kashihara N
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 19 Issue: 4 Pages: 567-575
- DOI
  10.1007/s10157-014-1029-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04838, KAKENHI-PROJECT-25461238, KAKENHI-PROJECT-25461263
[Presentation] Podocyte のカルシウム(Ca2+)動態に着目した非ステロイド性ミネラルコルチコイド受容体(MR)拮抗薬によるアルブミン尿改善効果の分子メカニズムの解明.2023
- Author(s)
  岩倉主、城所研吾、立川理絵、岸誠司、長洲一、柏原直樹、佐々木環.
- Organizer
  第45回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] 内皮機能障害はβカテニンの活性化によるM1/ M2マクロファージ分化誘導を介して、AKI to CKD transition を促進する.2023
- Author(s)
  高須将伸、岸誠司、長洲一、立川理絵、梶本恵莉子、平野憲、岩倉主、梅野怜奈、角谷裕之、城所研吾、佐々木環、柏原直樹.
- Organizer
  第13回腎不全研究会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] 糖尿病性腎臓病における内皮/上皮病態連関、NO/sGC 活性化不全の解明.2023
- Author(s)
  梶本恵莉子、高須将伸、立川理絵、岩倉主、梅野怜奈、城所研吾、岸誠司、長洲一、佐々木環、柏原直樹.
- Organizer
  第34回日本糖尿病性腎症研究会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] 糖尿病性腎臓病における非ステロイド系ミネラルコルチコイド受容体拮抗薬による腎保護機序の解明.2023
- Author(s)
  岩倉主、城所研吾、立川理絵、高須将伸、梶本恵莉子、平野憲、梅野怜奈、岸誠司、長洲一、佐々木環、柏原直樹.
- Organizer
  第34回日本糖尿病性腎症研究会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] 日本腎臓学会から：J-CKD-DBリアルワールドデータ活用による腎臓病研究2023
- Author(s)
  長洲一、矢野裕一朗、柏原直樹
- Organizer
  第43回医療情報学連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08333
[Presentation] Elucidation of the Molecular Mechanism of Albuminuria Improvement by Nonsteroidal Mineralocorticoid Receptor(MR) Antagonists Focusing on Podocyte Calcium (Ca2+)Dynamics.2023
- Author(s)
  Tsukasa Iwakura, Kengo Kidokoro, Seiji Kishi, Hajime Nagasu, Naoki Kashihara, Tamaki Sasaki.
- Organizer
  American Society of Nephrology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] Endothelial dysfunction exacerbates kidney dysfunction in ageing kidney via activation of inflammasome2022
- Author(s)
  Yoshihisa Wada, Hajime Nagasu, Hiroyuki Kadoya, Naoki Kashihara
- Organizer
  the29th ISH (The 29th Scientific Meeting of the International Society of Hypertension)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] eNOS/NO signaling regulates renal interstitial fibrosis by increasing cytoplasmic beta-catenin degradation2022
- Author(s)
  Masanobu Takasu, Hiroyuki Kadoya, Hajime Nagasu, Seiji Kishi, Tamaki Sasaki, Naoki Kashihara
- Organizer
  the29th ISH (The 29th Scientific Meeting of the International Society of Hypertension)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] 糖尿病性腎臓病の進展にはインフラマソームの活性化が関与する2022
- Author(s)
  梅野怜奈、長洲一、角谷裕之、城所研吾、岸　誠司、柏原直樹
- Organizer
  第３３回日本糖尿病性腎症研究会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] eNOS-NO pathway modulates AKI to CKD transition in IRI model mice via regulation of βCatenin translocation2022
- Author(s)
  Masanobu Takasu, Megumi Kondo, Hajime Nagasu, Hiroyuki Kadoya, Seiji Kishi, Kengo Kidokoro, Naoki Kashihara
- Organizer
  the29th ISH (The 29th Scientific Meeting of the International Society of Hypertension)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] 腎疾患進展におけるインフラマソーム活性化の意義2022
- Author(s)
  角谷裕之、長洲一、岸誠司、佐々木環、柏原直樹
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] eNOS-NO pathway regulates inflammasome activation in diabetic mice via modulation of CEBP translocation2022
- Author(s)
  Hajime Nagasu, Reiko Umeno, Hiroyuki Kadoya, Naoki Kashihara
- Organizer
  the29th ISH (The 29th Scientific Meeting of the International Society of Hypertension)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] マクロファージにおけるNrf2活性化はインフラマソーム活性化制御により糖尿病性腎臓病の進展を抑制する2021
- Author(s)
  近藤恵、長洲一、梅野怜奈、城所研吾、柏原直樹
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] SGLT2阻害薬による内皮NOS機能異常改善を介した腎保護効果の検証2021
- Author(s)
  近藤恵、城所研吾、角谷裕之、和田佳久、長洲一、佐々木環、柏原直樹
- Organizer
  第21回日本NO学会
- Data Source
  KAKENHI-PROJECT-21H02937
[Presentation] Evaluation of glomerular hemodynamic changes by SGLT2 inhibitor and ARB in type 2 diabetic rats using in vivo imaging2021
- Author(s)
  Yoshihisa Wada,Kengo Kidokoro,Reina Umeno,Atsuyuki Tokuyama,Megumi Kondo,Hiroyuki Kadoya, Hajime Nagasu,Tamaki Sasaki,Naoki Kashihara
- Organizer
  The 10th Chronic Kidney Disease Frontier Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] 内皮機能障害はinflammasome活性化を介して老化関連腎障害を促進させる。2020
- Author(s)
  長洲一、和田佳久、近藤恵、徳山敦之、角谷裕之、城所研吾、長洲一、柏原直樹
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] ENOS/NO SIGNALLING ATTENUATES GLOMERULAR INJURY IN DIABETIC MICE VIA SUPPRESSION OF INFLAMMASOME ACTIVATION2020
- Author(s)
  Nagasu H,Wada Y,Kadoya H,Kidokoro K,Kashihara N.
- Organizer
  the 18th Asian Pacific Congress of Nephrology (APCN 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] EVALUATION OF THE MECHANISM OF GLOMERULAR ARTERIOLE CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS2020
- Author(s)
  Nagasu H,Wada Y,Kidokoro K,Kadoya H,Kashihara N.
- Organizer
  the 18th Asian Pacific Congress of Nephrology (APCN 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] INFLAMMASOME ACTIVATION PLAYS A KEY ROLE ON THE PROGRESSION OF PERITONEAL FIBROSIS IN MICE2020
- Author(s)
  Kadoya H,Nagasu H,Sasaki T,Kashihara N.
- Organizer
  the 18th Asian Pacific Congress of Nephrology (APCN 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Activation of eNOS/sGC/PKG signaling pathway attenuates renal interstitial fibrosis via β-catenin degradation in mice2020
- Author(s)
  角谷裕之、長洲一、佐々木環、柏原直樹
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] SH3BP2 deficiency ameliorates murine systemic lupus erythematosus2020
- Author(s)
  Tomoyuki Mukai, Kyoko Kawahara, Masanori Iseki, Akiko Nagasu, Hajime Nagasu, Takahiko Akagi, Shoko Tsuji, Yasuyoshi Ueki, Katsuhiko Ishihara, Naoki Kashihara, Yoshitaka Morita
- Organizer
  The 22nd Asia Pacific League of Associations for Rheumatology (APLAR 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] 糖尿病性腎臓病におけるSGLT2阻害薬Canagliflozinの糸球体内皮機能改善効果の検討2020
- Author(s)
  近藤恵、城所研吾、和田佳久、徳山敦之、角谷裕之、長洲一、佐々木環、柏原直樹
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] DEFICIENT OF ENOS/NO PATHWAY PROMOTES AKI TO CKD TRANSITION AFTER ISCHEMIC REPERFUSION2020
- Author(s)
  Nagasu N,Kondo M,Kadoya H,Kidokoro K,Kashihara N.
- Organizer
  the 18th Asian Pacific Congress of Nephrology (APCN 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] The role of an adaptor protein SH3BP2 in the pathogenesis of systemic lupus erythematosus2020
- Author(s)
  Tomoyuki Mukai, Kyoko Kawahara, Masanori Iseki, Akiko Nagasu, Hajime Nagasu, Takahiko Akagi, Shoko Tsuji, Sumie Asano, Yasuyoshi Ueki, Katsuhiko Ishihara, Naoki Kashihara, Yoshitaka Morita
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプター蛋白SH3BP2 の自己免疫現象における役割の解明2020
- Author(s)
  河原恭子,　向井知之,　井関將典,　長洲晶子,　長洲一,　赤木貴彦,　辻尚子,　石原克彦,　柏原直樹,　植木靖好,　守田吉孝
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] SH3BP2 Deficiency Ameliorates Murine Systemic Lupus Erythematosus2020
- Author(s)
  Tomoyuki Mukai , Kyoko Kawahara , Masanori Iseki , Akiko Nagasu , Hajime Nagasu , Takahiko Akagi , Shoko Tsuji , Yasuyoshi Ueki , Katsuhiko Ishihara , Naoki Kashihara and Yoshitaka Morita
- Organizer
  2020 American College of Rheumatology(ACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] THE EFFECTS OF SGLT2 INHIBITORS ON GLOMERULAR HYPERFILTRATION AND OXIDATIVE STRESS IN MICE WITH DIABETIC KIDNEY DISEASE2020
- Author(s)
  Kondo M,Kidokoro K,Nagasu H,Sasaki T,Kashihara N.
- Organizer
  the 18th Asian Pacific Congress of Nephrology (APCN 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Bardoxolone methyl analog attenuates proteinuria-induced tubular damege by modulating mitochondrial function.2019
- Author(s)
  Nagasu H, Sogawa Y, Kidokoro K, Wigley W, Prokcsh J, Meyer C, Satoh M, Kashihara N
- Organizer
  ISN World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプター蛋白SH3BP2の自己免疫現象に対する役割の解明2019
- Author(s)
  河原恭子, 向井知之, 長洲晶子, 井関將典, 赤木貴彦, 長洲一, 植木靖好, 守田吉孝
- Organizer
  第47回日本臨床免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Evaluation of the diabetic glomerular hemodynamics by SGLT2 inhibitor empagliflozin using in vivo imaging.2019
- Author(s)
  K Kidokoro, D Cherney, A Bozovic, H Nagasu, M Satoh, T Sasaki, N Kashihara.
- Organizer
  ISN World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] The role of adopter protein SH3BP2 in a murine systemic lupus erythematosus model2019
- Author(s)
  Kyoko Kawahara,　Tomoyuki Mukai,　Akiko Nagasu,　Masanori Iseki,　Hajime Nagasu,　Shoko Tsuji,　Takahiko Akagi,　Yasuyoshi Ueki,　Yoshitaka Morita
- Organizer
  2019 American College of Rheumatology(ACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Effect of uremic toxin-indoxcyl sulfate on intestinal defensin expression in renal failure mice.2019
- Author(s)
  M Satoh, M Kondo, Y Wada, S Itano, K Kidokoro, H Nagasu, T Sasaki, N Kashihara.
- Organizer
  ISN World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] 内皮eVOS/NO/PKG経路はWnt/βcatenin活性化を負に制御し、M1/M2マクロファージ分化誘導を介して、AKI to CKD transitonに関与する2019
- Author(s)
  近藤恵、長洲一、和田佳久、角谷裕之、城所研吾、佐藤稔、佐々木環、柏原直樹
- Organizer
  第10回分子腎臓フォーラム
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Clarification of the Mechanism of Acute GFR Change by SGLT2 Inhibition with In Vivo Imaging Technique2019
- Author(s)
  Wada Y, Kidokoro K, Kondo M , Tokuyama A, Kadoya H, Nagasu H, Satoh M, Sasaki T, Kashihara N
- Organizer
  ASN　Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Bardoxolone methyl analog attenuates proteinuria-induced tubular damege by modulating mitochondrial function.2019
- Author(s)
  H Nagasu, Y Sogawa, K Kidokoro, W Wigley, J Prokcsh, C Meyer, M Satoh, N Kashihara.
- Organizer
  ISN World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] SH3BP2 gain-of-function mutation ameliorates lupus in B6.MRL-Faslpr mice2019
- Author(s)
  Akiko Nagasu
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway Underlies the Mechanisms of AKI to CKD Transition via Prolonged Activation of the Wnt/β-Catenin Pathway2019
- Author(s)
  Kondo M, Nagasu H, Sogawa Y, Kadoya H, Kidokoro K, Satoh M, Kashihara N
- Organizer
  ASN　Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプタータンパクSH3BP2の役割の解明2019
- Author(s)
  河原恭子, 向井知之, 長洲晶子, 井関將典, 赤木貴彦, 長洲一, 植木靖好, 守田吉孝
- Organizer
  第84回日本インターフェロン・サイトカイン学会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] eNOS-NO経路の破綻はNLRP3-Inflammasome活性化を促進させ腎障害を進展させる。2019
- Author(s)
  和田佳久、長洲一、近藤恵、十川裕史、角谷裕之、城所研吾、佐藤稔、柏原直樹
- Organizer
  第62回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-18K16015
[Presentation] SH3BP2 gain-of-function mutation ameliorates lupus in B6.MRL-Faslpr mice2019
- Author(s)
  Akiko Nagasu, Tomoyuki Mukai, Masanori Iseki, Hajime Nagasu, Kyoko Kawahara, Shoko Tsuji, Shunichi Fujita, Naoki Kashihara, Katsuhiko Ishihara, Yoshitaka Morita
- Organizer
  The 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Activation of the Keap1/Nrf2 Pathway Increases GFR by Increasing Glomerular Effective Filtration Area Without Affecting the Afferent/Efferent Arteriole Ratio2019
- Author(s)
  Kidokoro K,Nagasu H, Satoh M, Meyer C, Kashihara N
- Organizer
  ASN　Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] The role of inflammasomes in the development of chronic kidney diseases.2019
- Author(s)
  Nagasu H, Kashihara N
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプタータンパクSH3BP2の自己免疫現象に対する役割の解明2019
- Author(s)
  河原恭子,　向井知之,　長洲晶子,　井関　將典,　赤木貴彦,　長洲一,　植木靖好,　守田吉孝
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Nrf2 activator, RTAdh404, attenuates tubular Injury via Eliminating Mitochondrial ROS in proteinuria induced renal failure mice2018
- Author(s)
  Yuji Sogawa, Hajime Nagasu, Minoru Satoh, Tamaki Sasaki, Christian Wigley, Colin J. Meyer, Naoki Kashihara,
- Organizer
  ASN KIDNEY WEEK 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Evaluation of the glomerular hemodynamics alterations by SGLT2 inhibitor Empagliflozin using in vivo imaging.2018
- Author(s)
  K Kidokoro、A Uchida ,Y Sogawa,H Nagasu, Msatoh, T Sasaki, N Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Endothelial dysfunction exacerbates renal tubular cell injury through inflammasome activation in a hypertensive mouse model.2018
- Author(s)
  Yuji Sogawa, Hajime Nagasu, Megumi Kondo, Yoshihisa Wada, Hiroyuki Kadoya, Kengo Kidokoro, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara.
- Organizer
  ASN KIDNEY WEEK 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] RTAdh404 attenuates renal inflammation and fibrosis via mitochondrial protection in ICGN mice.2018
- Author(s)
  Y Sogawa,H Nagasu,A Uchida,S Itano,K Kidokoro,Y Haruna,M Satoh,T Sasaki,N Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] The association of microbiota alteration and intestinal barrier function in chronic renal failure mice2018
- Author(s)
  Minoru Satoh, Seiji Itano,Yuji Sogawa, Y Haruna, K kidokoro, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] eNOS -NO signaring attenuates renal fibrosis via suppression of catenin signaling.2018
- Author(s)
  H Nagasu, Y Sogawa, K Kidokoro, S Itano, M Satoh, T Sasaki, N Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] The eNOS/NO signaring attenuates glomerular injury in diabetic mice via suppression of inflammasome activation.2018
- Author(s)
  Y Sogawa,　H Nagasu,A Uchida,S Itano,K Kidokoro,Y Haruna,M Satoh,Ti Sasaki,N Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] The association of microbiota alteration and intestinal barrier function in chronic renal failure mice.2018
- Author(s)
  Minoru Satoh, Seiji Itano,Yuji Sogawa, Yoshisuke Haruna, Kengo kidokoro, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09722
[Presentation] DPP4 inhibitor linagliptin ameliorates diabetic kidneydisease through the protection of glomerular endothelial function in mice.2018
- Author(s)
  K Kidokoro、A Uchida ,Y Sogawa,H Nagasu, Msatoh, T Sasaki, N Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Evaluation of glomerular hemodynamic function by empagliflozin in diabetic mice using in vivo imaging.2018
- Author(s)
  Kengo kidokoro, Yuji Sogawa, Cherney D, Kulasingan V, Hajime Nagasu, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara
- Organizer
  American Diabetes Association 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Evaluation of the glomerular hemodynamis by the SGLT2 inhibitor empagliflozin using in vivo imaging.2018
- Author(s)
  Kengo Kidokoro, Yoshihisa Wada, Megumi Kondo, Yuji Sogawa, Hajime Nagasu, Minoru Satoh, Tamaki　Sasaki, Naoki Kashihara.
- Organizer
  55th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in Ins2Akita diabetic mice2018
- Author(s)
  Minoru Satoh, Seiji Itano, Yuji Sogawa, Athushi Uchida,K Kidokoro, H Nagasu, Y Haruna, Tamaki Sasaki, Naoki Kashihara
- Organizer
  ISN Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Nrf2 Activator, RTADh404, attenuates renal tubular Injury via Mitochondrial Protection in nephrotic model mice.2018
- Author(s)
  Yuji Sogawa, Hajime Nagasu, Megumi Kondo, Yoshihisa Wada, Kengo Kidokoro, Yoshisuke Haruna, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara.
- Organizer
  55th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02828
[Presentation] ENOS/NO Signaling Attenuates Glomerular Injury in Diabetic Mice via Suppression of Inflammasome Activation.2017
- Author(s)
  Sogawa Y, Nagasu H, Uchida A, Itano S, Satoh M, Sasaki T, Kashihara N
- Organizer
  54th ERA-EDTA CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] DPP-4阻害剤Linagliptinは血糖非依存性の内皮保護作用によりアルブミン尿を減少させる2017
- Author(s)
  内田篤志、十川裕史、板野精之、城所研吾、長洲一、佐藤、佐々木、柏原直樹
- Organizer
  第6回臨床高血圧フォーラム
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Evaluation of the effect of empagliflozin on improving hyperfiltration in diabetic nephropathy2017
- Author(s)
  Y. Sogawa, K. Kidokoro, A. Uchida, S. Itano, H. Nagasu, M. Satoh, T. Sasaki, N. Kashihara
- Organizer
  53RD ANNUAL MEETING OF THE EUROPEAN ASSOCIATION FOR THE STUDY OF DIABETES(EASD2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] ネフローゼ腎不全マウスの筋力低下に対する自発的車輪ランニングの効果2017
- Author(s)
  十川裕史、花田里美、内田篤志、板野精之、城所研吾、長洲一、佐藤稔、佐々木環、柏原直樹
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 内皮由来可溶性糖タンパクであるエンドカンの内皮細胞へ作用の検討2017
- Author(s)
  佐藤稔、花田里美、桑原篤憲、長洲一、城所研吾、佐々木環、柏原直樹
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 糖尿病においてeNOS/NO経路はインフラマソーム活性化の抑制を介して支給対象外を軽減する2017
- Author(s)
  十川裕史、長洲一、内田篤志、板野精之、城所研吾、佐藤稔、佐々木環、柏原直樹
- Organizer
  第6回臨床高血圧フォーラム
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] eNOS/NOシグナルはインフラマソーム抑制を介して糖尿病性腎症における糸球体障害の進展を軽減する2017
- Author(s)
  十川裕史、内田篤志、城所研吾、長洲一、佐藤稔、佐々木環、柏原直樹
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 横紋筋融解症においてNrf2活性化は尿細管抗酸化遺伝子群発現抑制を介して腎保護作用を有する2017
- Author(s)
  内田篤志、花田里美、十川裕史、城所研吾、長洲一、佐藤稔、佐々木環、柏原直樹
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Development of a Novel Model of Contrast-Induced AKI in Mice2017
- Author(s)
  Uchida A, Kidokoro K, Nagasu H, Satoh M, Sasaki T, Kashihara N.
- Organizer
  ASN Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] in vivo imagingを用いたSGLT2阻害薬Empagliflozinの糖尿病性腎障害抑制機序の解明2017
- Author(s)
  城所研吾、十川裕史、内田篤志、長洲一、佐藤稔、佐々木環、柏原直樹
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Infiltaration on M1 macrophages is Impaired but not M2,After Unilateral, Ureter Obstruction in NRF2 Deficient Mice.2017
- Author(s)
  Nagasu H, Sogawa Y, Satoh M, Kashihara N
- Organizer
  54th ERA-EDTA CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Evaluation of the Reno-Protective Effects of Empagliflozin in Diabetic Nephropathy Using In Vivo Imaging2017
- Author(s)
  Kidokoro K, Uchida A, Sogawa Y, Nagasu H, Satoh M, Sasaki T, Kashihara N
- Organizer
  ASN Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 虚血再灌流モデルにおいてeNOS-NO経路の破綻はAKI-CKD transitionを促進させる2017
- Author(s)
  長洲一、内田篤志、十川祐史、城所研吾、佐藤稔、佐々木環、柏原直樹
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] UUOモデルではNrf2欠損状態は腎内への炎症性マクロファージ持続浸潤を抑制する2017
- Author(s)
  十川裕史、長洲一、花田里美、内田篤志、板野精之、城所研吾、佐藤稔、佐々木環、柏原直樹
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 糸球体内皮由来eNOS-NO経路は上皮細胞におけるインフラマソーム活性化を抑制的に制御する2017
- Author(s)
  長洲一、十川裕史、佐藤稔、佐々木環、柏原直樹
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Activation of Endothelial NAD(P)H Oxidase Accelerates Early Glomerular Injury in Diabetic Mice.2016
- Author(s)
  Nagasu H, Satoh M, Itano S, Uchida A, Sogawa Y, Kashihara N
- Organizer
  HYPERTENSION SEOUL 2016 (26th Scientific Meeting of the ISH)
- Place of Presentation
  Coex,Seoul,Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Hypertension Promotes Islet Morphological Changes with Vascular Injury on Prediabetic Status in SHR-SP Rats.2016
- Author(s)
  Satoh M, Nagasu H, Haruna Y, Ihoriya T, Kadoya H, Sasaki T, Kashinara N
- Organizer
  HYPERTENSION SEOUL 2016 (26th Scientific Meeting of the ISH)
- Place of Presentation
  Coex,Seoul,Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Nrf2依存的Inflammasome活性化はM1 マクロファージの維持により炎症線維化に寄与する2016
- Author(s)
  長洲　一
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  宮城県仙台市仙台国際センター
- Data Source
  KAKENHI-PROJECT-16K19501
[Presentation] Renal Denervation Protects Renal Function by Suppressing NAD(P)H Oxidase Activity in Dahl Salt-Sensitive Rats.2016
- Author(s)
  Nagasu H, Satoh M, Itano S, Kashihara N
- Organizer
  HYPERTENSION SEOUL 2016 (26th Scientific Meeting of the ISH)
- Place of Presentation
  Coex,Seoul,Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Nrf2 Dependent Inflmmasome Activation Contributes to Maintain M1 Macrophage but Not M2 Infiltration in Kidney Disease Model2016
- Author(s)
  Yuji Sogawa, Hajime Nagasu, Atsushi Uchida, Seiji Itano, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara.
- Organizer
  ASN KIDNEY WEEK2016
- Place of Presentation
  Chicago, Illinois, United States
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Renoprotective Effect of 5-Aminolevulinic Acid in Rhabdomyolysis-Induced Acute Kidney Injury2016
- Author(s)
  Atsushi Uchida, Kengo Kidokoro, Hajime Nagasu, Minoru Satoh,Tamaki Sasaki, Naoki Kashihara
- Organizer
  第15回アジア太平洋腎臓学会（APCN2016) 15th Asian Pacific Congress of Nephrology & 52nd Australian and New Zealand Society of Nephrology ASM
- Place of Presentation
  Perth Convention and Exhibition Centre(Perth /Australia)
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] The Association and Its Mechanism between Microbiota Alteration and Intestinal-Barrier Function in Mice with Chronic Renal Failure2016
- Author(s)
  Seiji Itano, Minoru Satoh, Yuji Sogawa, Atsushi Uchida, Kengo Kidokoro, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara.
- Organizer
  ASN KIDNEY WEEK2016
- Place of Presentation
  Chicago, Illinois, United States
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 内皮障害はインフラマソーム活性化を促進し腎障害進展に寄与する2016
- Author(s)
  長洲　一
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都府京都市勧業館みやこめっせ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19501
[Presentation] Possible Implication of Xanthine Oxidase Activation on the Pathogenesis Diabetic Nephropathy2016
- Author(s)
  Itano S, Satoh M, Sogawa Y, Uchida A, Nagasu H, Sasaki T, Kashihara N
- Organizer
  HYPERTENSION SEOUL 2016 (26th Scientific Meeting of the ISH)
- Place of Presentation
  Coex,Seoul,Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] eNOS-NO Pathway Attenuates Chronic Inflammation via Nitric Oxide in Hypertensive Kidney Disease2016
- Author(s)
  Yuji Sogawa, Hajime Nagasu, Atsushi Uchida, Seiji Itano, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara.
- Organizer
  ASN KIDNEY WEEK2016
- Place of Presentation
  Chicago, Illinois, United States
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Possible Implication of Xanthine Oxidase Activation on the Pathogenesis Diabetic Nephropathy2016
- Author(s)
  Seiji Itanno, Minoru Satoh,Yuji Sogawa, Atsusi Uchida, Hajime Nagasu, Tamaki Sasaki ,Naoki Kashihara
- Organizer
  第15回アジア太平洋腎臓学会（APCN2016) 15th Asian Pacific Congress of Nephrology & 52nd Australian and New Zealand Society of Nephrology ASM
- Place of Presentation
  Perth Convention and Exhibition Centre(Perth /Australia)
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Cyclic GMP Dependent Protein Kinase-AKT Pathway is Essential for Compensatory Renal Hypertrophy and Maintenance Renal Function After Unilateral Nephrectomy.2016
- Author(s)
  Nagasu, Itano S, Uchida A, Satoh M, Kashihara N
- Organizer
  HYPERTENSION SEOUL 2016 (26th Scientific Meeting of the ISH)
- Place of Presentation
  Coex,Seoul,Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Endothelial Cells Regulate Inflammasome Activation Through Nitric Oxde in Hypertensive Kidney Disease.2016
- Author(s)
  長洲　一
- Organizer
  国際高血圧学会
- Place of Presentation
  韓国ソウル　International convention center
- Data Source
  KAKENHI-PROJECT-16K19501
[Presentation] Effects of Lanthanum Carbonate on Intestinal Bacterial Flora and Intestinal Barrier Function in Chronic Renal Failure Mice2016
- Author(s)
  Seiji Itano,Minoru Satoh,Atsushi Uchida,Yuji Sogawa,Hajime Nagasu,Kengo Kidokoro,Tamaki Sasaki,Naoki Kashihara
- Organizer
  第15回アジア太平洋腎臓学会（APCN2016) 15th Asian Pacific Congress of Nephrology & 52nd Australian and New Zealand Society of Nephrology ASM
- Place of Presentation
  Perth Convention and Exhibition Centre(Perth /Australia)
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] 内皮機能はインフラマソーム活性化を制御し腎疾患進展を抑制する2016
- Author(s)
  長洲　一
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16K19501
[Presentation] Endothelial Cells Regulate Inflammasome Activation Through Nitric Oxde in Hypertensive Kidney Disease.2016
- Author(s)
  Nagasu H, Satoh M, Sogawa Y, Kashihara N
- Organizer
  HYPERTENSION SEOUL 2016 (26th Scientific Meeting of the ISH)
- Place of Presentation
  Coex,Seoul,Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Possible Implication of Xanthine Oxidase Activation on the Pathogenesis Diabetic Nephropathy.2015
- Author(s)
  Seiji Itano, Minoru Satoh, Atsushi Uchida, Hiroyuki Kadoya, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara
- Organizer
  ASN　KIDNEY WEEK　2015
- Place of Presentation
  San Diego ,USA
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Effects of Lanthanum Carbonate on Intestinal Bacterial Flora in Chronic Renal Failure Mice.2015
- Author(s)
  Minoru Satoh, Hiroyuki Kadoya, Seiji Itano, Atsushi Uchida, Yuji Sogawa, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara
- Organizer
  ASN　KIDNEY WEEK　2015
- Place of Presentation
  San Diego ,USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Possible implication of xanthine oxidase activation on the pathogenesis diabetic nephropathy.2015
- Author(s)
  Seiji Itano, Minoru Satoh, Yuji Sogawa, Atsushi Uchida, Hiroyuki Kadoya, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara
- Organizer
  10th World Congress for Microcirculation
- Place of Presentation
  Kyoto International Conference Center,Kyoto
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[Presentation] Visualization of in vivo renin activity and its application to study the pathogenetic mechanisms of diabetic nephropathy.2015
- Author(s)
  Minoru Satoh, Kengo Kidokoro, Seiji Itano, Hajime Nagasu, Tamaki Sasaki, Naoki Kashihara
- Organizer
  10th World Congress for Microcirculation
- Place of Presentation
  Kyoto International Conference Center,Kyoto
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04838
[]

1. Kashihara Naoki (10233701)

# of Collaborated Projects: 9 results

# of Collaborated Products: 86 results
2. 城所研吾 (50435020)

# of Collaborated Projects: 9 results

# of Collaborated Products: 59 results
3. Satoh Minoru (70449891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 58 results
4. 角谷裕之 (70509265)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. 岸誠司 (10519507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Mukai Tomoyuki (00454421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. 春名克祐 (40341094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 桑原篤憲 (50368627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 井関將典 (30532353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. 守田吉孝 (50346441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
11. 矢野裕一朗 (10586241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 長尾智晴 (10180457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 桐田雄平 (30783097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 佐々木環 (30187124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. UEKI YASUYOSHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SUZUKI Takafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. YAMAMOTO Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 田宮元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 成田暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 樋田一徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 石原克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagasu Hajime 長洲 一

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老化関連腎障害におけるTRPC依存的Ca動態による糸球体内微小炎症の制御機構解明Principal Investigator

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sGC activation on the interaction between glomerular endothelial cells and podcyte.Principal Investigator

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Inflammasome activation in podocyte of diabetic kidney diseasesPrincipal Investigator

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The mechanism of inflammasome activation associated chronic inflammation on CKD.Principal Investigator

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[Journal Article] Oxidative stress and the role of redox signalling in chronic kidney disease.2024

Author(s)

Nagasu Hajime 長洲一