KOMATSU Mamoru 小松護

Researcher Number	40414057
Other IDs	https://orcid.org/0000-0001-8564-6385
Affiliation (based on the past Project Information) *help	2014 – 2021: 北里大学, 感染制御科学府, 講師 2014: 北里大学, 大学院感染制御科学府, 講師 2013 – 2014: 北里大学, その他の研究科, 講師 2012 – 2013: 北里大学, その他の研究科, 助教 2012: 北里大学, 大学院・感染制御科学府, 助教 … More 2011: 北里大学, 助教 2011: 北里大学, 大学院感染制御科学府, 助教 2010: 北里大学, 大学院・感染制御科学府, 助教 2009: Kitasato University, 北里生命科学研究所, 研究員 2008: Kitasato University, 基礎研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Applied microbiology / Basic Section 38020:Applied microbiology-related / Applied genomics Except Principal Investigator Science and Engineering / Applied genomics
Keywords	Principal Investigator 放線菌 / 二次代謝産物 / 線状プラスミド / 生合成遺伝子 / 異種発現 / Streptomyces avermitilis / 物質生産 / 接合伝達 / 二次代謝産物生産 / synthetic biology … More / secondary metabolism / 遺伝子増幅 / 合成生物学 / Streptomyces / conjugation / liner plasmid / secondary metabolite / actinophage / genome / Cre/loxP / Sterptomyces avermitilis / ポリケチド抗生物質 / 抗生物生産 / リボスタマイシン / カスガマイシン / ストレプトマイシン / アミノグリコシド抗生物質 / バイオインフォマティクス / 有用物質生産 / 応用微生物 / ゲノム / 産業微生物ゲノム … More Except Principal Investigator ゲノム / 抗生物質 / 2次代謝産物 / 放線菌 / 二次代謝産物 / 物質生産 / 発現調節 / 微生物 / 遺伝子 / バイオテクノロジー / 発現制御 / 応用微生物 / 最適化宿主 / 生合成 / 米国 / 国際情報交換 / 休眠遺伝子 / テルペン化合物 / 異種発現 / 生合成マシナリー / 産業微生物 / 染色体再構成 / 産業微生物ゲノム Less

部位特異的遺伝子増幅機能を応用した放線菌二次代謝産物生産能力増強システムの構築Principal Investigator
- Principal Investigator
  
  小松護
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Kitasato University
Comprehensive metabolic analysis of a model host for secondary metabolite production
- Principal Investigator
  
  Ikeda Haruo
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
Development of gene introduction system for stable production of secondary metobolites in engineered Streptomyces hostPrincipal Investigator
- Principal Investigator
  
  KOMATSU MAMORU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Kitasato University
Construction of linear plasmid vector for cloning of giant gene cluster for secondary metabolite biosynthesisPrincipal Investigator
- Principal Investigator
  
  KOMATSU MAMORU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Kitasato University
Heterologous secondary metabolite production in genome-minimized Streptomyces hostPrincipal Investigator
- Principal Investigator
  
  KOMATSU Mamoru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kitasato University
Versatile host for the heterologous expression of secondary metabolism.
- Principal Investigator
  
  IKEDA Haruo
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
Development of the comprehensive system for useful secondary metabolism and bioconversion of useful compounds
- Principal Investigator
  
  IKEDA Haruo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kitasato University
Construction of genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.Principal Investigator
- Principal Investigator
  
  KOMATSU Mamoru
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kitasato University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives2020
- Author(s)
  Kudo Kei、Hashimoto Takuya、Hashimoto Junko、Kozone Ikuko、Kagaya Noritaka、Ueoka Reiko、Nishimura Takehiro、Komatsu Mamoru、Suenaga Hikaru、Ikeda Haruo、Shin-ya Kazuo
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-020-17769-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05779, KAKENHI-PLANNED-16H06447
[Journal Article] Modifications to central carbon metabolism in an engineered Streptomyces host to enhance secondary metabolite production2020
- Author(s)
  Doi Shiori、Komatsu Mamoru、Ikeda Haruo
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 130 Issue: 6 Pages: 563-570
- DOI
  10.1016/j.jbiosc.2020.08.006
- NAID
  40022442999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05779, KAKENHI-PLANNED-16H06447
[Journal Article] An Unusual Extender Unit Is Incorporated into the Modular Polyketide Synthase of Scopranones Biosynthesis2019
- Author(s)
  Demachi Ayumu、Uchida Ryuji、Arima Shiho、Nagamitsu Tohru、Hashimoto Junko、Komatsu Mamoru、Kozone Ikuko、Shin-ya Kazuo、Tomoda Hiroshi、Ikeda Haruo
- Journal Title
  
  Biochemistry
  
  Volume: 58 Issue: 50 Pages: 5066-5073
- DOI
  10.1021/acs.biochem.9b00908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05779, KAKENHI-PLANNED-16H06447
[Journal Article] 1.Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a Streptomyces sp. Cryptic RiPP Biosynthetic Gene Cluster.2018
- Author(s)
  Kawahara T, Izumikawa M, Kozone I, Hashimoto J, Kagaya N, Koiwai H, Komatsu M, Fujie M, Sato N, Ikeda H, Shin-Ya K.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 81 Issue: 2 Pages: 264-269
- DOI
  10.1021/acs.jnatprod.7b00607
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07674, KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-26221204
[Journal Article] Distribution and functional analysis of the phosphopantetheinyl transferase superfamily in Actinomycetales microorganisms2018
- Author(s)
  Kim, J., Komatsu, M., Shin-ya, K., Omura, S., Ikeda, H.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 115 Issue: 26 Pages: 6828-6833
- DOI
  10.1073/pnas.1800715115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-16K07674
[Journal Article] Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms2017
- Author(s)
  Nara, A., Hashimoto, T., Komatsu, M., Nishiyama, M., Kuzuyama, T., Ikeda, H.
- Journal Title
  
  J. Antibiot.
  
  Volume: 印刷中 Issue: 5 Pages: 616-624
- DOI
  10.1038/ja.2017.33
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06453, KAKENHI-PLANNED-16H06447
[Journal Article] Heterologous production of kasugamycin, an aminoglycoside antibiotic from Streptomyces kasugaensis, in Streptomyces lividans and Rhodococcus erythropolis L-88 by constitutive expression of the biosynthetic gene cluster2017
- Author(s)
  Kasuga, K., Sasaki, A., Matsuo, T., Yamamoto, C., Minato, Y., Kuwahara, N., Fujii, C., Kobayashi, M., Agematsu, H., Tamura, T., Komatsu, M., Ishikawa, J., Ikeda, H., Kojima, I.
- Journal Title
  
  Appl. Microbiol. Biotechnol
  
  Volume: - Issue: 10 Pages: 4259-4268
- DOI
  10.1007/s00253-017-8189-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-16K07674, KAKENHI-PROJECT-16K07993
[Journal Article] tRNA-dependent aminoacylation of an amino sugar intermediate in the biosynthesis of a streptothricin-related antibiotic2016
- Author(s)
  Maruyama, C., Niikura, H., Izumikawa, M., Hashimoto, J., Shin-ya, K., Komatsu, M., Ikeda, H., Kuroda, M., Sekizuka, T., Ishikawa, J., Hamano, M.
- Journal Title
  
  Appl. Environ. Microbiol.
  
  Volume: 82 Issue: 12 Pages: 3640-3648
- DOI
  10.1128/aem.00725-16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-15K14724
[Journal Article] High production of a class III lantipeptide AmfS in Streptomyces griseus2016
- Author(s)
  Takano, H., Matsui, Y., Nomura, J., Fujimoto, M., Katsumata, N., Koyama, T., Mizuno, I., Amano, S., Shiratori-Takano, H., Komatsu, M., Ikeda, H., Ueda, K.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 81 Issue: 1 Pages: 1-12
- DOI
  10.1080/09168451.2016.1238297
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06447
[Journal Article] Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms.2016
- Author(s)
  2.Yamada Y., Komatsu M., Ikeda H.
- Journal Title
  
  J. Antibiot (Tokyo)
  
  Volume: 印刷中 Issue: 7 Pages: 515-523
- DOI
  10.1038/ja.2015.147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25450112, KAKENHI-PLANNED-16H06447
[Journal Article] Novel thioviridamide derivative-JBIR-140: heterologous expression of the gene cluster for thioviridamide biosynthesis.2015
- Author(s)
  Izumikawa M, Kozone I, Hashimoto J, Kagaya N, Takagi M, Koiwai H, Komatsu M, Fujie M, Satoh N, Ikeda H, Shin-Ya K.
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 印刷中 Issue: 8 Pages: 533-536
- DOI
  10.1038/ja.2015.20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25450112, KAKENHI-PROJECT-26221204
[Journal Article] Terpene synthases are widely distributed in bacteria2015
- Author(s)
  Y. Yamada, T. Kuzuyama, M. Komatsu, K. Shin-ya, S. Omura, D.E. Cane, H. Ikeda
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 112 Issue: 3 Pages: 857-862
- DOI
  10.1073/pnas.1422108112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108006, KAKENHI-PROJECT-25450112, KAKENHI-PROJECT-26292058
[Journal Article] Discovery of gene cluster for mycosporine-like amino acid biosynthesis from Actinomycetales microorganisms and production of a novel mycosporine-like amino acid by heterologous expression2014
- Author(s)
  K. T. Miyamoto, M. Komatsu, H. Ikeda
- Journal Title
  
  Appl. Environ. Microbiol.
  
  Volume: 80 Issue: 16 Pages: 5028-5036
- DOI
  10.1128/aem.00727-14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108006, KAKENHI-PROJECT-25450112
[Journal Article] Engineered Streptomyces Avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites2013
- Author(s)
  M. Komatsu, K. Komatsu, H. Koiwai, Y. Yarnada, I. Kozone, M. Izumikawa, J. Hashimoto, M. Takagi, S. Omura, K. Shin-ya, D. E. Cane, and H. Ikeda
- Journal Title
  
  ACS Synth. Biol.
  
  Volume: 2 Issue: 7 Pages: 384-396
- DOI
  10.1021/sb3001003
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108006, KAKENHI-PROJECT-23780089, KAKENHI-PROJECT-25450112
[Journal Article] Site-specific genome integration in alphaproteobacteria mediated by TG1 integrase2012
- Author(s)
  Morita, K., Morimura, K., Fusada, N., Komatsu, M., Ikeda, H., Hirano, N., Takahashi, H
- Journal Title
  
  Appl. Microbiol. Biotechnol
  
  Volume: 93 Issue: 1 Pages: 295-304
- DOI
  10.1007/s00253-011-3545-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780089
[Journal Article] Pleiotropic control of secondary metabolism and morphological development by KsbC, a butyrolactone autoregulator receptor homologue in Kitasatospora setae.2012
- Author(s)
  Aiyada Aroonsri
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 78 Issue: 22 Pages: 8015-8124
- DOI
  10.1128/aem.02355-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780089, KAKENHI-PROJECT-24780071, KAKENHI-PLANNED-22108006
[Journal Article] Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene and albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite.2011
- Author(s)
  Takamatsu, S. Lin, X. Nara, A. Komatsu, M. Cane, D.E. Ikeda, H.
- Journal Title
  
  Microb.Biotechnol. 4
  
  Pages: 184-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] The autoregulator-receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis2011
- Author(s)
  Miyamoto, K., Kitani, S., Komatsu, M., Ikeda, H., Nihira, T.
- Journal Title
  
  Microbiology
  
  Volume: 157 Issue: 8 Pages: 2266-2275
- DOI
  10.1099/mic.0.048371-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360404, KAKENHI-PLANNED-22108006, KAKENHI-PROJECT-23780089
[Journal Article] Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites : Hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis.2011
- Author(s)
  Takamatsu, S. Lin, X. Fushinobu, S. Shoun, H, Komatsu, M. Cane, D.E. Ikeda, H.
- Journal Title
  
  J.Antibiot. 64
  
  Pages: 65-71
- NAID
  10030637591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Komatsu, M., et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA.
  
  Volume: 107 Pages: 2646-2651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Komatsu, M. Uchiyama, Takuma, Cane, D.E. Omura, S. Ikeda, H.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 107
  
  Pages: 2646-2651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  komatsu M.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America (PNAS) 107(6)
  
  Pages: 2646-2651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710154
[Journal Article] Genome mining in Streptomyces avermitilis : Cloning and characterization of SAV_76, the synthase for a new sesquiterpene. avermitilol.2010
- Author(s)
  Chou, W.K.W. Fanizza, I. Uchiyama, T. Komatsu, M. Ikeda, H. Cane, D.E.
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 8850-8851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Komatsu, M., et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 2646-2651
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108006
[Journal Article] In vitro characterization of the sitespecific recombination system based on actinophage TG1 integrase.2010
- Author(s)
  Morita K, Yamamoto T, Fusada N, Komatsu M, Ikeda H, Hirano N, Takahashi H.
- Journal Title
  
  Mol. Genet. Genomics 282巻
  
  Pages: 607-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710154
[Journal Article] Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Komatsu M, Uchiyama T, Omura S, Cane DE, Ikeda H. Komatsu M, Uchiyama T, Omura S, Cane DE, Ikeda H.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A. 107巻
  
  Pages: 2646-2651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710154
[Journal Article] In vitro characterization of the site-specific recombination system based on actinophage TG1 integrase.2009
- Author(s)
  Morita, K. Yamamoto, T. Fusada, N. Komatsu, M. Ikeda, H. Hirano, N. Takahashi, H.
- Journal Title
  
  Mol.Genet.Genome. 282
  
  Pages: 607-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] The site-specific recombination system of actinophage TG1.2009
- Author(s)
  Morita, K. Yamamoto, T. Fusada, N. Komatsu, M. Ikeda, H. Hirano, N. Takahashi, H.
- Journal Title
  
  FEMS Microbiol.Lett. 297
  
  Pages: 234-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Genome mining in Streptomyces avermitilis : A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.2009
- Author(s)
  Jiang, J. Tetzlaff, C.N. Takamatsu, S. Iwatsuki, M. Komatsu, M. Ikeda, H. Cane, D.E.
- Journal Title
  
  Biochemistry 48
  
  Pages: 6431-6440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetes.2009
- Author(s)
  Tanaka Y, Komatsu M, Okamoto S, Tokuyama S, Kaji A, Ikeda H, Ochi K.
- Journal Title
  
  Appl. Environ. Microbiol. 75巻
  
  Pages: 4919-4922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710154
[Journal Article] Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetes.2009
- Author(s)
  Tanaka, Y. Komatsu, M. Okamoto, S. Tokuyama, S. Kaji, A. Ikeda, H. Ochi, K.
- Journal Title
  
  Appl.Env.Microbiol. 75
  
  Pages: 4919-4922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.2009
- Author(s)
  Jiang J, Tetzlaff CN, Takamatsu S, Iwatsuki M, Komatsu M, Ikeda H, Cane DE.
- Journal Title
  
  Biochemistry 14;48巻
  
  Pages: 6431-6440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710154
[Journal Article] The site-specific recombination system of actinophage TG1.2009
- Author(s)
  Morita K, Yamamoto T, Fusada N, Komatsu M, Ikeda H, Hirano N, Takahashi H.
- Journal Title
  
  FEMS Microbiol. Lett. 297巻
  
  Pages: 234-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710154
[Journal Article] Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol2009
- Author(s)
  M. Komatsu, M. Tsuda, S. Omura, H. Oikawa, H. Ikeda
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 105
  
  Pages: 7423-7427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Journal Article] Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol.2008
- Author(s)
  Komatsu, M. Tsuda, M. Omura, S. Oikawa, H. Ikeda, H.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 105
  
  Pages: 7422-7427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] 中心代謝改変による有用物質生産への応用2020
- Author(s)
  土居志織、小松護、池田治生
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19K05779
[Presentation] ファージ由来integraseによるexcisinase非依存的な切り出し反応2017
- Author(s)
  小松護、池田治生
- Organizer
  第32回(2017年度)日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-16K07674
[Presentation] 複数の受容菌存在下で接合伝達の成立に影響を及ぼす因子の探索2016
- Author(s)
  作田郁子、水口千穂、橋本詢子、小曽根郁子、小松護、新家一男、池田治生、岡田憲典、野尻秀昭
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌ゲノム縮小株を宿主とした二次代謝産物生合成遺伝子の異種発現2016
- Author(s)
  小松　護
- Organizer
  第15回　微生物研究会
- Place of Presentation
  神奈川県藤沢市　日本大学生物資源科学部湘南キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-16K07674
[Presentation] 放線菌汎用宿主における二次代謝産物生産に適した構成的発現プロモーターの探索2016
- Author(s)
  小松護、池田治生
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌ゲノム縮小株を宿主とした二次代謝産物生合成遺伝子の異種発現2016
- Author(s)
  小松　護
- Organizer
  第60回　日本薬学会関東支部大会
- Place of Presentation
  東京都文京区　東京大学大学院薬学系研究科　山上会館
- Invited
- Data Source
  KAKENHI-PROJECT-16K07674
[Presentation] 生合成酵素エンジニアリングによるstreptothricinのβ-lysine ologopeptide鎖長制御2015
- Author(s)
  川崎春香、丸山千登勢、小松護、池田治生、片野肇、濱野吉十
- Organizer
  2015年度日本放線菌学会大会
- Place of Presentation
  富山国際会議場(富山県富山市)
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] Streptothricin生合成におけるラクタム環形成の解明2015
- Author(s)
  丸山千登勢、泉川美穗、小松護、新家一男、池田治生、濱野吉十
- Organizer
  2015年度日本放線菌学会大会
- Place of Presentation
  富山国際会議場(富山県富山市)
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 抗生物質ストレプトスリシン生合成機構の解明2014
- Author(s)
  丸山千登勢、本山賢人、馬場信行、川畑球一、泉川美穂、増田裕一、小松護、土井隆行、新家一男、池田治生、濱野吉十
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  神奈川県川崎市・明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌由来新規セスキテルペン合成酵素遺伝子の解析2014
- Author(s)
  山田佑樹、小松護、池田治生
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  神奈川県川崎市・明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌における線状プラスミドを用いた二次代謝産物生合成遺伝子群の接合伝達2014
- Author(s)
  小松護、小曽根郁子、橋本絢子、新家一男、池田治生
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  神奈川県川崎市・明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] Labdane型ジテルペン合成酵素遺伝子のswappingによる機能解析2013
- Author(s)
  山田佑樹、西出崇人、小松護、池田治生
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台・東北大学川内北キャンパス
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 放線菌におけるマイコスポリン様アミノ酸生合成遺伝子群の解析2013
- Author(s)
  宮本聖子、小松護、池田治生
- Place of Presentation
  仙台・東北大学川内北キャンパス(口頭発表)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 放線菌汎用宿主の開発と物質生産への応用2013
- Author(s)
  小松護
- Organizer
  酵素工学研究会第70回講演会
- Place of Presentation
  東京都・東京大学山上会館
- Invited
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] Engineered Streptomyces host for heterologous expression of biosyntheic gene cluster for secondary metabolites2013
- Author(s)
  Ikeda, H. Komatsu, M. Komatsu, K. Koiwai, H. Yamada, Y. Kozone, I. Izumikawa, M. Hashimoto, J. Takagi, M. Omura, S. Shin-ya, K. Cane, DE
- Organizer
  12th International Symposium on Genetics of Industrial Microorganisms
- Place of Presentation
  Cancun, Mexico
- Data Source
  KAKENHI-PLANNED-22108006
[Presentation] 線状プラスミドを利用した二次代謝産物生合成遺伝子クラスター導入法2013
- Author(s)
  小松護、小曽根郁子、橋本詢子、新家一男、片岡正和、池田治生
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台・東北大学川内北キャンパス
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] プラスミドを利用した二次代謝産物生合成遺伝子クラスター導入法2013
- Author(s)
  小松護、小曽根郁子、橋本詢子、新家一男、片岡正和、池田治生
- Place of Presentation
  仙台・東北大学川内北キャンパス(口頭発表)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 休眠遺伝子群の異種発現による新規マイコスポリンの生産2013
- Author(s)
  宮本聖子、小松護、池田治生
- Organizer
  2013年度日本放線菌学会大会
- Place of Presentation
  広島県広島市・メルパルク広島
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌汎用宿主の開発と物質生産への応用2013
- Author(s)
  小松護
- Organizer
  酵素工学研究会第７０回講演会
- Place of Presentation
  東京都・東京大学山上会館
- Invited
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 放線菌由来新規セスキテルペン合成酵素遺伝子の解析2013
- Author(s)
  山田佑樹、小松護、池田治生
- Organizer
  2013年度日本放線菌学会大会
- Place of Presentation
  広島県広島市・メルパルク広島
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] Labdane 型ジテルペン合成酵素遺伝子のswapping による機能解析2013
- Author(s)
  山田佑樹、西出崇人、小松護、池田治生
- Place of Presentation
  仙台・東北大学川内北キャンパス(口頭発表)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 放線菌汎用宿主の開発と物質生産への応用2013
- Author(s)
  小松護
- Organizer
  2013年度日本放線菌学会大会
- Place of Presentation
  広島県広島市・メルパルク広島
- Invited
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌におけるマイコスポリン様アミノ酸生合成遺伝子群の解析2013
- Author(s)
  宮本聖子、小松護、池田治生
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台・東北大学川内北キャンパス
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 生合成マシナリー構築のための汎用宿主の開発2012
- Author(s)
  小松護、池田治生
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都(口頭発表)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 放線菌におけるマイコスポリン様アミノ酸生合成遺伝子群の解析2012
- Author(s)
  宮本聖子、小松護、池田治生
- Place of Presentation
  東京都府中市・府中の森芸術劇場(口頭発表)
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Streptomyces avermitilis SUKA株を宿主としたシキミ酸経路由来二次代謝産物の異種生産2012
- Author(s)
  小松護、尾仲宏康、Marvyn J. Bibb、池田治生
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都府　京都女子大学
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 線状プラスミドを利用した二次代謝産物生合成遺伝子クラスター導入法2012
- Author(s)
  小松護、小曽根郁子、新家一男、片岡正和、池田治生
- Organizer
  2012年度（第27回）日本放線菌学会大会
- Place of Presentation
  東京都府中市・府中の森芸術劇場
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Labdane型ジテルペン合成酵素遺伝子のswappingによる機能解析2012
- Author(s)
  山田佑樹、西出崇人、小松護、池田治生
- Organizer
  2012年化学生物研究会
- Place of Presentation
  神奈川県・慶応義塾大学日吉キャンパス藤原洋記念ホール
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 線状プラスミドを利用した二次代謝産物生合成遺伝子クラスター導入法2012
- Author(s)
  小松護、小曽根郁子、新家一男、片岡正和、池田治生
- Place of Presentation
  東京都府中市・府中の森芸術劇場(ポスター発表)
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Labdane 型ジテルペン合成酵素遺伝子のswapping による機能解析2012
- Author(s)
  山田佑樹、西出崇人、小松護、池田治生
- Organizer
  2012年化学生物研究会
- Place of Presentation
  慶応義塾大学日吉キャンパス藤原洋記念ホール(口頭発表)
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 転写に関わる遺伝子変異による異種二次代謝産物生合成遺伝子群発現の改変2012
- Author(s)
  小松護
- Organizer
  文科省科研費補助金新学術領域研究「生合成マシナリー：生物活性物質構造多様性創出システムの解明と制御」第2回公開シンポジウム
- Place of Presentation
  東京大学　薬学部大講堂
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Streptomyces avermitilis SUKA 株を宿主としたシキミ酸経路由来二次代謝産物の異種生産2012
- Author(s)
  小松護、尾仲宏康、Mervyn J. Bibb、池田治生
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都(口頭発表)
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Labdane型ジテルペン合成酵素遺伝子のswappingによる機能解析2012
- Author(s)
  山田佑樹、西出崇人、小松護、池田治生
- Organizer
  第22回ドリコールおよびイソプレノイド研究会
- Place of Presentation
  新潟県・新潟大学駅南キャンパス
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Labdane 型ジテルペン合成酵素遺伝子のswapping による機能解析2012
- Author(s)
  山田佑樹、西出崇人、小松護、池田治生
- Organizer
  第22回ドリコールおよびイソプレノイド研究会
- Place of Presentation
  新潟・新潟大学駅南キャンパス(口頭発表)
- Year and Date
  2012-09-29
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 放線菌におけるマイコスポリン様アミノ酸生合成遺伝子群の解析2012
- Author(s)
  宮本聖子、小松護、池田治生
- Organizer
  2012年度（第27回）日本放線菌学会大会
- Place of Presentation
  東京都府中市・府中の森芸術劇場
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 生合成マシナリー構築のための汎用宿主の開発2012
- Author(s)
  小松護、池田治生
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都府京都女子大学
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Comprehensive analysis of terpene compounds from prokaryote2011
- Author(s)
  Yu-ki Yamada, Takuma Uchiyama, Mamoru Komatsu, Haruo Ikeda
- Organizer
  The 2011 Annual meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  北海道・札幌市(ポスター発表)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] 転写に関わる遺伝子変異による異種二次代謝産物生合成遺伝子群発現の改変文部科学省科学研究費補助金新学術領域研究生合成マシナリー:生物活性物質構造多様性創出システムの解明と制御2011
- Author(s)
  小松護
- Organizer
  第2回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] The autoregulator-receptor homologue AvaR3 is a global regulator controlling antibiotic production and cell morphology of Streptomyces avermitilis2011
- Author(s)
  Kiyoko Miyamoto, Shigeru Kitani, Mamoru Komatsu, Haruo Ikeda, Takuya Nihira
- Organizer
  The 2011 Annual meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  北海道・札幌市
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Comprehensive analysis of terpene compounds from prokaryote2011
- Author(s)
  Yu-ki Yamada, Takuma Uchiyama, Mamoru Komatsu and Haruo Ikeda
- Organizer
  The 2011 Annual Meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress (IUMS2011)
- Place of Presentation
  北海道札幌市　札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Heterologous expression of biosynthetic gene cluster for secondary metabolite derived from shikimate pathway in engineered Streptomyces avermitilis2011
- Author(s)
  Mamoru Komatsu, Hiroyasu Onaka, Mervyn J. Bibb, Hruo Ikeda
- Organizer
  The 2011 Annual meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  北海道・札幌市(ポスター発表)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Effect of Refampicin-Resistant Mutation on the Heterologous Expression of Secondary metabolism in Gemone-Engineered Streptomyces avermitilis2011
- Author(s)
  Mamoru Komatsu, Kozo Ochi, Hruo Ikeda
- Organizer
  16th International Symposium on the Biology of Actinomycetes
- Place of Presentation
  PuerutoVallarta,Mexico(ポスター発表)
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] The autoregulator-receptor homologue AvaR3 is a global regulator controlling antibiotic production and cell morphology of Streptomyces avermitilis2011
- Author(s)
  Kiyoko Miyamoto, Shigeru Kitani, Mamoru Komatsu, Haruo Ikeda, Takuya Nihira
- Organizer
  The 2011 Annual meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  北海道・札幌市(ポスター発表)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Effect of Rifampicin-Resistant Mutation on The Heterologous Expression of Secondary Metabolism in Genome-Engineered Streptomyces avermitilis2011
- Author(s)
  Mamoru Komatsu, Kozo Ochi, Haruo Ikeda
- Organizer
  16th International Symposium on the Biology of Actinomycetes
- Place of Presentation
  Puerto Vallarta / Mexico
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Heterologous expression of biosynthetic gene cluster for secondary metabolite derived from shikimate pathway in engineered Streptomyces avermitilis2011
- Author(s)
  Mamoru Komatsu, Hiroyasu Onaka, Mervyn J. Bibb, Haruo Ikeda
- Organizer
  The 2011 Annual meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  北海道・札幌市(口頭発表)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Heterologous expression of biosynthetic gene cluster for secondary metabolite derived from shikimate pathway in engineered Streptomyces avermitilis2011
- Author(s)
  Mamoru Komatsu, Hiroyasu Onaka, Mervyn J. Bibb and Haruo Ikeda
- Organizer
  The 2011 Annual Meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress (IUMS2011)
- Place of Presentation
  北海道札幌市　札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] TG1 ファージインテグラーゼを用いたα プロテオバクテリアゲノム改変技術の開発2011
- Author(s)
  森田健太郎、森村浩司、房田直記、小松護、池田治生、平野展孝、高橋秀夫
- Organizer
  第63回日本生物工学会大会
- Place of Presentation
  東京(口頭発表)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] The autoregulator-receptor homologue AvaR3 is a global regulator controlling antibiotic production and cell morphology of Streptomyces avermitilis2011
- Author(s)
  Kiyoko Miyamoto, Shigeru Kitani, Mamoru Komatsu, Haruo Ikeda and Takuya Nihira
- Organizer
  The 2011 Annual Meeting of the Society for Actinomycetes Japan joined with International Union of Microbiological Societies 2011 Congress (IUMS2011)
- Place of Presentation
  北海道札幌市　札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23780089
[Presentation] Characterization of relA mutant of industrial microorganism Streptomyces avermitilis2010
- Author(s)
  Komatsu, M.Tanaka, Y.Ochi, K.Ikeda, H.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2010-06-30
- Data Source
  KAKENHI-PLANNED-22108006
[Presentation] 産業微生物の二次代謝産物生産に対する緊縮制御因子ppGppの応用2010
- Author(s)
  小松護
- Organizer
  2010年度日本農芸化学会大会
- Place of Presentation
  東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] Optimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Ikeda, H.Komatsu, M.Uchiyama, T.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  Melbourne, Australia(Invited Symposium)
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PLANNED-22108006
[Presentation] Characterization of relA mutant of industrial microorganism Streptomyces avermitilis.2010
- Author(s)
  Komatsu M., Tanaka Y., Ochi K., Ikeda H.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms.
- Place of Presentation
  Melbourone, Australia
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] Optimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Ikeda H., Komatsu M., Uchiyama T.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms.
- Place of Presentation
  Melbourone, Australia
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] Waking up bacterial sleeping genes: a new method to elicit bacterial capabilities.2010
- Author(s)
  Ochi K., Tanaka Y., Komatsu M., Hosaka H., Ikeda H.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms.
- Place of Presentation
  Melbourone, Australia
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] 産業微生物の二次代謝産物生産に対する緊縮制御因子ppGppの応用2010
- Author(s)
  小松護
- Organizer
  2010年度日本農芸化学会大会
- Place of Presentation
  東京大学駒場キャンパス
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] Optimized Streptomyces host for the heterologous expression of secondary metabolism.2010
- Author(s)
  Ikeda, H.Komatsu, M.Uchiyama, T.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  Melbourne, Australia(Invited Symposium)
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] Characterization of relA mutant of industrial microorganism Streptomyces avermitilis2010
- Author(s)
  Komatsu, M.Tanaka, Y.Ochi, K.Ikeda, H.
- Organizer
  11^<th> International Symposium on the Genetics of Industrial Microorganisms
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2010-06-30
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] 異なったストレプトマイシン耐性変異(rsmGおよびrpsL)導入による放線菌の抗生物質生産性の増強放線菌由来フラボヘモグロビンパラログに関する研究Streptomyces avermitilis SUKAlにおける4-ヒドロキシ酪酸の発酵生産の構築16員環マクロライドBafilomycinの生合成遺伝子群の解析16員環マクロライドbafIlomycInの側鎖生合成遺伝子の解析産業利用放線菌を宿主としたァミノグリコシド抗生物質の生産ァクテノアァージTGIの産生するSer型インテグテーゼによる部位特異的組み換え機構の解析アクテノァァージTGIインテグラーゼの部位特異的組み換えに関わる配列要素の解析2009
- Author(s)
  1. 田中幸徳, 小松護, 岡本晋, 徳山真治, 池田治生, 越智幸三2. 加藤慶一, 池田宗一郎, 吉本明弘, 黒木進吾, 矢嶋俊介, 池田治生, 大澤貫寿, 祥雲弘文3. 信殿正光, 春日和, 志村洋一郎, 古澤結子, 田母神繁, 小林正之, 池田治生, 小嶋郁夫4. 奈良綾子, 沼田淳, 小松護, 高松智, 葛山智久, 池田治生5. 沼田淳, 奈良綾子, 小松護, 池田治生, 葛山智久, 西山真6. 小松護, 高野英晃, 春日和, 高松智, 上田賢志, 小嶋郁夫, 池田治生T. 森田健太郎, 山本智之, 房田直記, 小松護, 池田治生, 平野展孝, 高橋秀夫8. 山本智之, 森田健太郎, 房田直記, 小松護, 池田治生, 平野展孝, 高橋秀夫
- Organizer
  日本農芸化学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] Streptomyces avermitilisにおけるアミノグリコシド抗生物質の生産2009
- Author(s)
  小松護
- Organizer
  2009年度日本放線菌学会大会
- Place of Presentation
  秋田市
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] 産業利用放線菌を宿主としたアミノグリコシド抗生物質の生産2009
- Author(s)
  小松護
- Organizer
  2009年度日本農芸化学会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] Streptomyces avermitilisにおけるアミノグリコシド抗生物質の生産2009
- Author(s)
  小松護
- Organizer
  2009年度日本放線菌学会大会
- Place of Presentation
  秋田ヒューホテル(秋田市)
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] 産業利用放線菌を宿主としたアミノグリコシド抗生物質の生産2009
- Author(s)
  小松護
- Organizer
  2009年度日本農芸化学会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] Identification of genes for bacterial monoterpene biosynthesis2008
- Author(s)
  小松護
- Organizer
  UK-Japan Workshop 2008, Genomics of Antibiotic-producing Actinomycetes : Implications and Applications
- Place of Presentation
  東京都市ケ谷
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] 微生物ゲノムデーターベースからの異臭物質(2-methylisoborneol)生合成遺伝子の同定2008
- Author(s)
  小松護
- Organizer
  2008年度日本放線菌学会大会
- Place of Presentation
  山梨市
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] Identification of genes for bacterial monoterpene biosynthesis.2008
- Author(s)
  Komatsu M
- Organizer
  UK-Japan Workshop 2008, Genomics ofAntibiotic producing Actinomycetes: Implications and Applications
- Place of Presentation
  東京
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] 微生物ゲノムデーターベースからの異種物質(2-methyhsobomeol)生合成遺伝子の同定2008
- Author(s)
  小松護
- Organizer
  2008年度日本放線菌学会大会
- Place of Presentation
  山梨県山梨市
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] 16員環マクロライドBafilomycinの生合成遺伝子群の解析Streptomyces avermitilisにおけるオートレギュレータ制御系についてストレプトマイシン弱耐性変異rmsG導入によるStreptomyces属の二次代謝能の変化微生物ゲノムデーターベースからの異臭物質(2-methylisoborneol)生合成遺伝子の同定2008
- Author(s)
  1. 奈良綾子, 小松護, 高橋洋子, 藤田信之, 池田治生2. 宮本聖子, 木谷茂, 池田治生, 仁平卓也3. 田中幸徳, 岡本晋, 小松護, 徳山真治, 池田治生, 越智幸三4. 小松護, 津田宗哉, 大村智, 及川英秋, 池田治生
- Organizer
  日本放線菌学会
- Place of Presentation
  フルーツパーク富士屋ホテル
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20310122
[Presentation] 微生物ゲノムデーターベースからの異種物質(2-methylisobomeol)生合成遺伝子の同定2008
- Author(s)
  小松護
- Organizer
  2008年度グラム陽性細菌のゲノム生物学研究会
- Place of Presentation
  東京都代々木
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20710154
[Presentation] 生合成酵素のエンジニアリングによるstreptothrisinのβ-lysine oligopeptide鎖長制御
- Author(s)
  丸山千登勢、川崎春香、小松護、池田治生、濱野吉十、
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県(岡山大学津島キャンパス)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 巨大生合成遺伝子群導入のための線状プラスミドベクターの開発
- Author(s)
  小松護、小曽根郁子、橋本詢子、新家一男、池田治生
- Organizer
  2014年度日本放線菌学会大会
- Place of Presentation
  茨城県つくば市(つくばカピオ)
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] Mycobacterium属由来セスキテルペン合成酵素遺伝子の解析
- Author(s)
  山田佑樹、小松護、池田治生
- Organizer
  2014年度日本放線菌学会大会
- Place of Presentation
  茨城県つくば市(つくばカピオ)
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] Streptomyces属放線菌における伝達生線状プラスミドベクターを利用した二次代謝産物生合成遺伝子の導入
- Author(s)
  小松護、池田治生
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県(岡山大学津島キャンパス)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 放線菌由来新規ジテルペン合成酵素遺伝子の解析
- Author(s)
  山田佑樹、小松護、新家一男、池田治生
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県(岡山大学津島キャンパス)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 抗生物質streptothrisinのcarbamoyl-D-gulosamine構造に関する生合成研究
- Author(s)
  丸山千登勢、加藤さやか、泉川美穗、小松護、池田治生、新家一男、濱野吉十
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県(岡山大学津島キャンパス)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25450112
[Presentation] 抗生物質Streptothrisinのカルバモイルグロサミン構造に関する生合成研究
- Author(s)
  丸山千登勢、本山賢人、泉川美穗、小松護、池田治生、新家一男、濱野吉十
- Organizer
  2014年度日本放線菌学会大会
- Place of Presentation
  茨城県つくば市(つくばカピオ)
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25450112

1. IKEDA Haruo (90159632)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
2. TAKAMATSU Satoshi (30236351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 葛山智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 仁平卓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 木谷茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOMATSU Mamoru 小松 護

Research Projects

Research Products

Co-Researchers

部位特異的遺伝子増幅機能を応用した放線菌二次代謝産物生産能力増強システムの構築Principal Investigator

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Comprehensive metabolic analysis of a model host for secondary metabolite production

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Development of gene introduction system for stable production of secondary metobolites in engineered Streptomyces hostPrincipal Investigator

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Construction of linear plasmid vector for cloning of giant gene cluster for secondary metabolite biosynthesisPrincipal Investigator

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Heterologous secondary metabolite production in genome-minimized Streptomyces hostPrincipal Investigator

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Versatile host for the heterologous expression of secondary metabolism.

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Development of the comprehensive system for useful secondary metabolism and bioconversion of useful compounds

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Construction of genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.Principal Investigator

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[Journal Article] In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives2020

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DOI

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[Journal Article] Modifications to central carbon metabolism in an engineered Streptomyces host to enhance secondary metabolite production2020

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NAID

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[Journal Article] An Unusual Extender Unit Is Incorporated into the Modular Polyketide Synthase of Scopranones Biosynthesis2019

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DOI

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[Journal Article] 1.Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a Streptomyces sp. Cryptic RiPP Biosynthetic Gene Cluster.2018

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DOI

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[Journal Article] Distribution and functional analysis of the phosphopantetheinyl transferase superfamily in Actinomycetales microorganisms2018

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[Journal Article] Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms2017

Author(s)

KOMATSU Mamoru 小松護