SHIRATO Kazuya 白戸憲也

… Alternative Names

白戸憲也シラトカズヤ

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Researcher Number	40415477
Other IDs	https://orcid.org/0000-0002-3375-9799
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所バイオインフォマティクス・オミクス研究部, 室長
Affiliation (based on the past Project Information) *help	2021 – 2022: 国立感染症研究所, ウイルス第三部, 室長 2016 – 2020: 国立感染症研究所, ウイルス第三部, 主任研究官 2015: 国立感染症研究所, ウイルス第3部, 主任研究官 2013 – 2014: 国立感染症研究所, ウイルス第3部, 主任研究員 2009 – 2013: National Institute of Infectious Diseases, ウイルス第3部, 主任研究官 … More 2010: National Institute of Infectious Diseases, ウイルス第三部, 主任研究官 2008: National Institute of Infectious Diseases, ウイルス3部 2007 – 2008: National Institute of Infectious Diseases, ウイルス第3部第5室, 研究員 2007: 国立感染症研究所, ウイルス第3部, 研究員 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Virology Except Principal Investigator Virology
Keywords	Principal Investigator エチオピア / ヒトコブラクダ / MERS-CoV / HMC-1 / ヒトRSウイルス / 小児感染症学 / Spike protein / スパイクタンパク質 / Virus replication / Neutralization … More / Ethiopia / Africa / MERSコロナウイルス / MERS / RARRES2 / Ephrin-B2 / RSウイルス / プロテアーゼ / Air-Liquid Interface培養 / TMPRSS2 / カテプシンL / 継代 / ヒトコロナウイルス / ウイルス複製 / MDCK / RSV / A549 / 脱顆粒化 / 肥満細胞 / サイトケラチン18 / サイトケラチン8 / CX_3CR1 / degranulation / Mast Cell … More Except Principal Investigator スパイク(S)蛋白 / 脳内継代 / 乳飲みマウス / ブタ伝染性下痢ウイルス(PEDV) / recetor-indeendent infection / マウス肝炎ウイルス / ウイルス受容体 / 巨細胞形成 / 神経病原性 / 豚下痢症ウイルス(PEDV) / コロナウイルス / 病原性 Less

Study on the virological difference between African and Middle Eastern strains of MERS-CoVPrincipal Investigator
- Principal Investigator
  
  Kazuya Shirato
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  National Institute of Infectious Diseases
Studies on the role of Ephrin-B2 and RARRES2 in replication of RS virusPrincipal Investigator
- Principal Investigator
  
  Shirato Kazuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Institute of Infectious Diseases
Studies on the Middle East Respiratory Coronavirus in dromedary camels in EthiopiaPrincipal Investigator
- Principal Investigator
  
  Shirato Kazuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  National Institute of Infectious Diseases
Studies on the effect of the virus isolation and passage for the original viral entry routePrincipal Investigator
- Principal Investigator
  
  SHIRATO Kazuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Identification of host cell factors relating the replication of respiratory syncytial virusPrincipal Investigator
- Principal Investigator
  
  SHIRATO Kazuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Institute of Infectious Diseases
Identification of non-immunological signals that can induce degranulation of mast cells during RSV infectionPrincipal Investigator
- Principal Investigator
  
  SHIRATO Kazuya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Institute of Infectious Diseases
Studies on receptor-independent infection of coronaviruses and its implication in the pathogenesis
- Principal Investigator
  
  TAGUCHI Fumihiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Studies on the role of Mast cell in RSV infectionPrincipal Investigator
- Principal Investigator
  
  白戸憲也
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Institute of Infectious Diseases

All 2023 2022 2020 2019 2018 2017 2016 2012 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] LABIO21 No.64 2016年4月号「ヒトコロナウイルス」2016
- Author(s)
  白戸憲也
- Total Pages
  4
- Publisher
  日本実験動物協会
- Data Source
  KAKENHI-PROJECT-26460563
[Journal Article] Single Amino Acid Substitution in the Receptor Binding Domain of Spike Protein Is Sufficient To Convert the Neutralization Profile between Ethiopian and Middle Eastern Isolates of Middle East Respiratory Coronavirus2023
- Author(s)
  Sugimoto Satoko、Kakizaki Masatoshi、Kawase Miyuki、Kawachi Kengo、Ujike Makoto、Kamitani Wataru、Sentsui Hiroshi、Shirato Kazuya
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 2
- DOI
  10.1128/spectrum.04590-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06441, KAKENHI-PROJECT-23K05542
[Journal Article] Detection of the ORF1 Gene Is an Indicator of the Possible Isolation of Severe Acute Respiratory Syndrome Coronavirus 22022
- Author(s)
  Shirato Kazuya、Kakizaki Masatoshi、Tomita Yuriko、Kawase Miyuki、Takeda Makoto
- Journal Title
  
  Pathogens
  
  Volume: 11 Issue: 3 Pages: 302-302
- DOI
  10.3390/pathogens11030302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06441
[Journal Article] Less Frequent Sequence Mismatches in Variants of Concern (VOCs) of SARS-CoV-2 in the Real-Time RT-PCR Assays Developed by the National Institute of Infectious Diseases, Japan2022
- Author(s)
  Shirato Kazuya、Matsuyama Shutoku、Takeda Makoto
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 75 Issue: 1 Pages: 96-101
- DOI
  10.7883/yoken.JJID.2021.213
- NAID
  130008143962
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2022-01-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06441
[Journal Article] Ultra-Rapid Real-Time RT-PCR Method for Detecting Middle East Respiratory Syndrome Coronavirus Using a Mobile PCR Device, PCR11002020
- Author(s)
  Kazuya Shirato, Naganori Nao, Shutoku Matsuyama, and Tsutomu Kageyama
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 73 Issue: 3 Pages: 181-186
- DOI
  10.7883/yoken.JJID.2019.400
- NAID
  130007845449
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2020-05-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04642
[Journal Article] Development of Genetic Diagnostic Methods for Detection for Novel Coronavirus 2019(nCoV-2019) in Japan2020
- Author(s)
  Kazuya Shirato, Naganori Nao, Harutaka Katano, Ikuyo Takayama, Shinji Saito, Fumihiro Kato, Hiroshi Katoh, Masafumi Sakata, Yuichiro Nakatsu, Yoshio Mori, Tsutomu Kageyama, Shutoku Matsuyama, Makoto Takeda
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 73 Issue: 4 Pages: 304-307
- DOI
  10.7883/yoken.JJID.2020.061
- NAID
  130007879354
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2020-07-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04642
[Journal Article] Detecting Amplicons of Loop-Mediated Isothermal Amplification (LAMP)2019
- Author(s)
  Kazuya Shirato
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 63 Pages: 407-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10133
[Journal Article] Middle East Respiratory Syndrome coronavirus in dromedaries in Ethiopia is antigenically different from the Middle East isolate EMC2019
- Author(s)
  Kazuya Shirato, Simenew Keskes Melaku, Kengo Kawachi, Naganori Nao, Naoko Iwata-Yoshikawa, Miyuki Kawase, Wataru Kamitani, Shutoku Matsuyama, Tesfaye Sisay Tessema, Hiroshi Sentsui
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 10 Pages: 1326-1326
- DOI
  10.3389/fmicb.2019.01326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04642
[Journal Article] Development of Fluorescent Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) using Quenching probes for the detection of the Middle East Respiratory Syndrome Coronavirus2018
- Author(s)
  Kazuya Shirato*, Shohei Semba, Sherif A. El-Kafrawy, Ahmed M. Hassan, Ahmed M. Tolah, Ikuyo Takayama, Tsutomu Kageyama, Tsugunori Notomi, Wataru Kamitani, Shutoku Matsuyama and Esam Ibraheem Azhar
- Journal Title
  
  Journal of Virological Methods
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04642
[Journal Article] Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry2017
- Author(s)
  Shirato K, Kanou K, Kawase M, and Matsuyama S
- Journal Title
  
  Journal of Virology
  
  Volume: 91(1) Issue: 1
- DOI
  10.1128/jvi.01387-16
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460563
[Journal Article] Increased replication of respiratory syncytial virus in the presence of cytokeratin 8 and 18.2012
- Author(s)
  Shirato K, Ujike M, Kawase M, Matsuyama S.
- Journal Title
  
  J Med Virol.
  
  Volume: 84 Issue: 2 Pages: 365-370
- DOI
  10.1002/jmv.23196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790509, KAKENHI-PROJECT-23791205
[Journal Article] Increased Replication of Respiratory Syncytial Virus in the Presence of Cytokeratin 8 and 182012
- Author(s)
  Shirato K, Ujike M, Kawase M, and Matsuyama S
- Journal Title
  
  J Med. Virol
  
  Volume: 84 Pages: 365-370
- Data Source
  KAKENHI-PROJECT-23791205
[Journal Article] Protease-mediated entry via endosome of human coronavirus 229E.2009
- Author(s)
  Kawase M, Shirato K, Matsuyama S, Taguchi F
- Journal Title
  
  J. Virol 83
  
  Pages: 712-721
- Data Source
  KAKENHI-PROJECT-19390135
[Journal Article] Mast cell degranulation is induced by A549 airway epithelial cell infected with respiratory syncytial virus2009
- Author(s)
  Kazuya Shirato, and Fumihiro Taguchi
- Journal Title
  
  Virology 386
  
  Pages: 88-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790748
[Journal Article] Protease-mediated entry via endosome of human coronavirus 229E2009
- Author(s)
  Kawase M, Shirato K, Matsuyama S, Taguchi F.
- Journal Title
  
  Journal of Virology 8
  
  Pages: 712-721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390135
[Journal Article] Indirect induction of mast cell degranulation and migration by respiratory syncytial virus infection.2009
- Author(s)
  Shirato K, Taguchi F
- Journal Title
  
  Virology 386
  
  Pages: 88-93
- Data Source
  KAKENHI-PROJECT-19390135
[Journal Article] Mast cell degranulation is induced by A549 airway epithelial cell infected with respiratory syncytial virus.2009
- Author(s)
  Kazuya Shirato*, Fumihiro Taguchi.
- Journal Title
  
  Virology. 386
  
  Pages: 88-93
- Data Source
  KAKENHI-PROJECT-19790748
[Journal Article] Co-infection of respiratory bacterium with SARS coronavirus induces an exacerbated pneumonia in mice.2008
- Author(s)
  Ami Y, Nagata N, Shirato K, Watanabe R, Iwata N, Nakagaki K, Fukushi S, Saijo M, Morikawa S, Taguchi F
- Journal Title
  
  Microbiol. Immunol 52
  
  Pages: 118-127
- Data Source
  KAKENHI-PROJECT-19390135
[Journal Article] Entry from cell surface of SARS coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein.2008
- Author(s)
  Watanabe R, Matsyama S, Shirato K, Maejima M, Fukushi S, Morikawa S, Taguchi F
- Journal Title
  
  J. Virol 82
  
  Pages: 11985-11991
- Data Source
  KAKENHI-PROJECT-19390135
[Journal Article] Entry from cell surface of SARS coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein2008
- Author(s)
  Watanabe R, Matsuyama S, Shirato K, Maejima M, Fukushi S, Morikawa S, Taguchi F.
- Journal Title
  
  Journal of Virology 82
  
  Pages: 11985-11991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390135
[Presentation] エチオピアのヒトコブラクダから分離された中東呼吸器症候群コロナウイルスの病原性は中東分離株であるEMC株と異なる2019
- Author(s)
  白戸憲也、Simenew Keskes Melaku, 河内健吾、直亨則、岩田奈織子、川瀬みゆき、神谷亘、松山州徳、Tesfaye Sisay Tessema、泉對博
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04642
[Presentation] Development of Fluorescent Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) using Quenching probes for the detection of the Middle East Respiratory Syndrome Coronavirus2018
- Author(s)
  Kazuya Shirato, Shohei Semba, Sherif A. El-Kafrawy, Ahmed M. Hassan, Ahmed M. Tolah, Ikuyo Takayama, Tsutomu Kageyama, Tsugunori Notomi, Wataru Kamitani, Shutoku Matsuyama and Esam Ibraheem Azhar
- Organizer
  American Society for Virology 37th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04642
[Presentation] Characterization of Middle East Respiratory Syndrome coronavirus in dromedary camels in Ethiopia2018
- Author(s)
  Kazuya Shirato, Simenew KesKes Melaku, Kengo Kawachi, Naganori Nao, Shutoku Matsuyama, Wataru Kamitani, Tesfaye Sisay Tessema and Hiroshi Sentsui
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04642
[Presentation] 細胞骨格蛋白cytokeratin8/18がrespiratory syncytial virus(RSV)の複製に与える影響について2010
- Author(s)
  白戸憲也、川瀬みゆき、氏家誠、松山州徳
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21791022
[Presentation] 細胞骨格蛋白cytokeratin8/18がrespiratory syncytial virus (RSV)の複製に与える影響について2010
- Author(s)
  白戸憲也、川瀬みゆき、氏家誠、松山州徳
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21791022
[Presentation] 幕貫通型セリンプロテアーゼTMPRSS2による豚流行性下痢症ウイルス(PEDV)の細胞融合活性の誘導2009
- Author(s)
  白戸憲也
- Organizer
  第57回日本ウイルス学会
- Place of Presentation
  東京
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-19390135
[Presentation] The expression of transmembrane serine protease TMPRSS2 induces cell fusion during porcine epidemic diarrhea virus infection.2009
- Author(s)
  Shirato K
- Organizer
  The 9^<th> Awaji International Forum on Infection and Immunity.
- Place of Presentation
  淡路
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-19390135
[Presentation] Respiratory syncytial virus (RSV)感染における肥満細胞の役割2008
- Author(s)
  白戸憲也, 田口文宏
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19790748
[Presentation] Respiratory syncytial virus (RSV)感染における肥満細胞の役割2008
- Author(s)
  白戸憲也、田口文広
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19790748
[Presentation] ヒトコロナウイルス(HCoV)229Eの細胞侵入機構の解析2008
- Author(s)
  田口文広, 川瀬みゆき, 白戸憲也, 松山州徳
- Organizer
  第56回日本ウイルス学会総会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-19390135
[Presentation] ヒトコロナウイルス(HCoV)229Eのスパイク(S)蛋白をもつVSVシュードタイプウイルスの作製とHCoVの細胞侵入機構解析2007
- Author(s)
  白戸憲也、川瀬みゆき、田口文広
- Organizer
  第55回に本ウイルス学会総会、
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-19390135

1. TAGUCHI Fumihiro (30107429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. WATANABE Rihito (30129746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. HIRAI Asuka (50450557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 泉對博 (10355167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SENTSUI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 氏家誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIRATO Kazuya 白戸 憲也

白戸 憲也 シラト カズヤ

Research Projects

Research Products

Co-Researchers

Study on the virological difference between African and Middle Eastern strains of MERS-CoVPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the role of Ephrin-B2 and RARRES2 in replication of RS virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the Middle East Respiratory Coronavirus in dromedary camels in EthiopiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the effect of the virus isolation and passage for the original viral entry routePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of host cell factors relating the replication of respiratory syncytial virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of non-immunological signals that can induce degranulation of mast cells during RSV infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on receptor-independent infection of coronaviruses and its implication in the pathogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the role of Mast cell in RSV infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] LABIO21 No.64 2016年4月号 「ヒトコロナウイルス」2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Single Amino Acid Substitution in the Receptor Binding Domain of Spike Protein Is Sufficient To Convert the Neutralization Profile between Ethiopian and Middle Eastern Isolates of Middle East Respiratory Coronavirus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of the ORF1 Gene Is an Indicator of the Possible Isolation of Severe Acute Respiratory Syndrome Coronavirus 22022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Less Frequent Sequence Mismatches in Variants of Concern (VOCs) of SARS-CoV-2 in the Real-Time RT-PCR Assays Developed by the National Institute of Infectious Diseases, Japan2022

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Ultra-Rapid Real-Time RT-PCR Method for Detecting Middle East Respiratory Syndrome Coronavirus Using a Mobile PCR Device, PCR11002020

Author(s)

Journal Title

SHIRATO Kazuya 白戸憲也

白戸憲也シラトカズヤ

[Book] LABIO21 No.64 2016年4月号「ヒトコロナウイルス」2016