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YAMANE Shoji  山根 昌治

ORCIDConnect your ORCID iD *help
Researcher Number 40419148
Affiliation (based on the past Project Information) *help 2008: 独立行政法人国立病院機構(相模原病院臨床研究センター), 病態総合研究部, 特別研究員
2007: 独立行政法人国立病院機構(相模原病院臨床研究センター), 診断・治療研究部, 研究室長
2007: Clinical Research Center, National Hospital Organization Sagamihara Hospital, Division of Pathomechanisms, PhD, Group Manager
2006: 独立行政法人国立病院機構(相模原病院臨床研究センター), 診断治療研究部, 研究部長
Review Section/Research Field
Except Principal Investigator
Orthopaedic surgery
Keywords
Except Principal Investigator
変形性関節症 / インテグリン / Osteoarthritis / Cartilage tissue engineering / Integrin / Dedifferentiation / Chondrocte / ERK / 再生医学 / 脱分化 … More / 軟骨細胞 / 腫瘍破死因子 / 関節リウマチ / 切断酵素 / 腫瘍壊死因子 / 異化反応 / ファイブロネクチン Less
  • Research Projects

    (3 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (9 People)
  •  軟骨基質の異化の包括的な制御による変形性関節症の進行抑制に関する基礎的研究

    • Principal Investigator
      FUKUI Naoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
  •  Investigation for the mechanism of shedding for tumor necrosis factor-α and its pathological significance in rheumatoid arthritis

    • Principal Investigator
      HIKITA Atuhiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
  •  An exploratory research for prevention of chondrocyte dedifferentiation and treatment for osteoarthritis through the regulation of integrin actitivy

    • Principal Investigator
      FUKUI Naoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital

All 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Regional differences in chondrocyte metabolism in osteoarthritis. A detailed analysis by laser capture microdissection2008

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka S, Yamane S, Suzuki R, Sandell LJ, Ochi T.
    • Journal Title

      Arthritis Rheum 58

      Pages: 154-163

    • Data Source
      KAKENHI-PROJECT-19791052
  • [Journal Article] LIGHT Induces Cell Proliferation and Inflammatory Responses of Rheumatoid Arthritis Synovial Fibroblasts via Lymphotoxin beta Receptor.2008

    • Author(s)
      Ishida S, Yamane S, Ochi T, Nakano S, Mori T, Juji T, Fukui N, Itoh T, Suzuki R.
    • Journal Title

      J Rheumatol. Jun ; 35(6)

      Pages: 960-968

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Journal Article] Regional differences in chondrocyte metabolism in osteoarthritis. A detailed analysis by laser capture microdissection.2008

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Hikita A, Mitomi H, Mori T, Juji T, Katsuragawa Y, Yamamoto S, Sawabe M, Yamane S, Suzuki R, Sandell LJ, Ochi T.
    • Journal Title

      Arthritis Rheum 58

      Pages: 154-163

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Journal Article] TNF-alpha induces the expression of BMP-2 through transcriptional and post-transcriptional regulatory mechanisms2006

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Hikita A, Mitomi H, Mori T, Juji T, Katsuragawa Y, Yamamoto S, Sawabe M, Yamane S, Suzuki R, Sandell LJ, Ochi T.
    • Journal Title

      J Biol Chem 281

      Pages: 27229-41

    • Data Source
      KAKENHI-PROJECT-19791052
  • [Journal Article] TNF-α induces the expression of BMP-2 through transcriptional and post-transcriptional regulatory mechanisms.2006

    • Author(s)
      Fukui N, Ikeda T, Ohnuki T, Tanaka S, Yamane S, Suzuki R, Sandell LT, Ochi T.
    • Journal Title

      J Biol Chem 281

      Pages: 27229-41

    • Data Source
      KAKENHI-PROJECT-18390424
  • [Journal Article] Involvement of a disintegrin and metalloproteinase 10 and 17 in shedding of tumor necrosis factor-α

    • Author(s)
      Hikita A, Tanaka N, Yamane S, Ikeda Y, Furukawa H, Tohma S, Suzuki R, Tanaka S, Mitomi H, Fukui N.
    • Journal Title

      Biochem Cell Biol (in press)

    • Data Source
      KAKENHI-PROJECT-19791052
  • [Journal Article] Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

    • Author(s)
      Yamane S, Fukui N, ほか (14名中11番目)
    • Journal Title

      Journal of inflammation (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659394
  • [Journal Article] Involvement of a disintegrin and metalloproteinase 10 and 17 in shedding of tumor necrosis factor-α

    • Author(s)
      Atsuhiko Hikita, Nobuho Tanaka, Shoji Yamane, Yasuko Ikeda, Hiroshi Furukawa, Shigeto Tohma, Ryuji Suzuki, Sakae Tanaka, Hiroyuki Mitomi and Naoshi Fukui
    • Journal Title

      Biochemistry and Cell Biology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791052
  • [Journal Article] The interaction of monocytes with rheumatoid synovial cells is a key step in LIGHT-mediated inflammatory bone destruction

    • Author(s)
      Ishida, S, Yamane S, Nakano S, Yanagimoto T, et al.
    • Journal Title

      Immunology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659394
  • [Journal Article] Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients.

    • Author(s)
      Yamane S, Ishida S, Hanamoto Y, Kumagai K, Masuda R, Tanaka K, Shiobara N, Yamane N, Mori T, Juji T, Fukui N, Itoh T, Ochi T, Suzuki R.
    • Journal Title

      J Inflamm (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Journal Article] Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients.

    • Author(s)
      Yamane S, Fukui N, et. al.(14名中11番目)
    • Journal Title

      J Inflamm (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Journal Article] Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

    • Author(s)
      Yamane S, Fukui N, ほか (14名中11番目)
    • Journal Title

      Journal of inflammation (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Presentation] ヒト変性性関節症罹患軟骨におけるanabolic factorの探索2008

    • Author(s)
      福井尚志、池田泰子、大貫俊幸、田中信帆、石田 暁、山根昌治、疋田温彦、桂川陽三、山本精三、宮本恵成、鈴木隆二
    • Organizer
      第21回日本軟骨代謝学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19791052
  • [Presentation] Identification of possible regulatory molecules for chondrocyte anabolism in osteoarthritic cartilage.2007

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Ishida S, Yamane S, Mitomi H, Hikita A, Yamamoto S, Katsuragawa Y, Suzuki R.
    • Organizer
      2007 World Congress on Osteoarthritis.
    • Place of Presentation
      Ft. Lauderdale, FL. USA.
    • Data Source
      KAKENHI-PROJECT-19659394
  • [Presentation] Identification of possible regulatory molecules for chondrocyte anabolism in osteoarthritic cartilage2007

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Ishida S, Yamane S, Mitomi H, Hikita A, Yamamoto S, Katsuragawa Y, Suzuki R.
    • Organizer
      2007 World Congress on Osteoarthritis
    • Place of Presentation
      Lauderdale, FL, USA
    • Data Source
      KAKENHI-PROJECT-19791052
  • [Presentation] Identification of possible regulatory molecules for chondrocyte anabolism in osteoarthritic cartilage.2007

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Ishida S, Yamane S, Mitomi H, Hikita A, Yamamoto S, Katsuragawa Y, Suzuki R.
    • Organizer
      2007 World Congress on Osteoarthritis. Ft.
    • Place of Presentation
      Lauderdale, FL, USA.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Presentation] Identification of possible regulatory molecules for chondrocyte anabolism in osteoarthritic cartilage.2007

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Ishida S, Yamane S, Mitomi H, Hikita A, Yamamoto S, Katsuragawa Y, Suzuki R.
    • Organizer
      2007 World Congress on Osteoarthritis.
    • Place of Presentation
      Ft. Lauderdale, FL, USA.
    • Data Source
      KAKENHI-PROJECT-18390424
  • [Presentation] Integrin αvβ5 may be responsible for the suppression of cartilage matrix genes and formation of cytoskeletons during dedifferentiation in the monolayer cultured adult human articular chondrocytes2006

    • Author(s)
      Fukui N, Ikeda Y, Ohnuki T, Tanaka N, Hikita A, Yamane S, Suzuki R, Ochi T, Katsuragawa Y, Yamamoto S.
    • Organizer
      2006 World Congress on Osteoarthritis
    • Place of Presentation
      Prague, Czech Republic.
    • Data Source
      KAKENHI-PROJECT-19791052
  • 1.  FUKUI Naoshi (10251258)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 2.  SUZUKI Ryuji (70373470)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 3.  HIKITA Atuhiko (60443397)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  TANAKA Nobuho (60530920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 5.  FURUKAWA Hiroshi (00372293)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  TOUMA Shigeto (50207528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  MITOMI Hiroyuki (90181940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  MASUDA Riako (10416050)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  IKEDA Yasuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results

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