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Ohbayashi Norihiko  大林 典彦

ORCIDConnect your ORCID iD *help
… Alternative Names

大林 典彦  オオバヤシ ノリヒコ

OHBAYASHI Norihiko  大林 典彦

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Researcher Number 40421979
Other IDs
Affiliation (Current) 2025: 筑波大学, 医学医療系, 准教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 筑波大学, 医学医療系, 准教授
2015 – 2017: 筑波大学, 医学医療系, 准教授
2012 – 2014: 東北大学, 生命科学研究科, 助教
2010 – 2011: 東北大学, 大学院・生命科学研究科, 助教
2010: 北海道大学, 大学院・薬学研究院, 助教
2007: Hokkaido University, Grad. Sch. Pharm. Sci., Assistant Professor
2006: 北海道大学, 大学院薬学研究院, 助手
Review Section/Research Field
Principal Investigator
Cell biology / Basic Section 44010:Cell biology-related / Orthopaedic surgery
Except Principal Investigator
Biological pharmacy / Medical pharmacy
Keywords
Principal Investigator
色素細胞 / 小胞輸送 / 低分子量Gタンパク質 / メラニン / メラノソーム / Rab / Tyrp1 / チロシナーゼ / Arf6 / 樹状突起 … More / 低分子量G蛋白質 / 蛋白質分解 / タンパク質分解 / オルガネラ / 品質管理 / ユビキチン / メラニン合成酵素 / プロテアソーム / フォルスコリン / メラノサイト / 突起形成 / エフェクター / 膜輸送 / Varp / ノックアウトマウス / サイトカイン / FGF / 骨芽細胞 / 軟骨細胞 / 破骨細胞 … More
Except Principal Investigator
STAT3 / 癌 / シグナル伝達 / 自己免疫疾患 / サイトカイン / 薬学 / autoimmune diseases / cytokine / Drug development / cancer / Signal transduction / Immunology / 創薬 / 免疫学 / 炎症 / IL-6 / がん / 免疫 / タンパク質 / 測定法 / 生体分子 Less
  • Research Projects

    (9 results)
  • Research Products

    (80 results)
  • Co-Researchers

    (12 People)
  •  色素細胞におけるRabとArfの協調Principal Investigator

    • Principal Investigator
      大林 典彦
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      University of Tsukuba
  •  Physiological function of Arf6 in melanocytesPrincipal Investigator

    • Principal Investigator
      Ohbayashi Norihiko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      University of Tsukuba
  •  Degradation mechanism of effector molecules by Rab small GTPasePrincipal Investigator

    • Principal Investigator
      Ohbayashi Norihiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      University of Tsukuba
  •  Effects of Varp on the activation of melanocytesPrincipal Investigator

    • Principal Investigator
      OHBAYASHI Norihiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Tohoku University
  •  Studies on the molecular mechanism of biogenesis and maturation of melanosomes regulated by a novel Rab32/38-binding proteinPrincipal Investigator

    • Principal Investigator
      OHBAYASHI Norihiko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Tohoku University
  •  Activation and regulation of the disease-related IL-6/STAT3 signaling

    • Principal Investigator
      MATSUDA Tadashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  エピジェニック効果を指標とした新規臨床検査法の確立

    • Principal Investigator
      MATSUDA Tadashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Hokkaido University
  •  破骨細胞形成におけるFGFシグナルとサイトカインシグナルのクロストークPrincipal Investigator

    • Principal Investigator
      大林 典彦
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Hokkaido University
  •  Molecular mechanisms of STAT3 activation and their therapeutic applications

    • Principal Investigator
      MATSUDA Tadashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking2022

    • Author(s)
      Ogura Yukino、Ohbayashi Norihiko、Kanaho Yasunori、Kawaguchi Atsushi、Funakoshi Yuji
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298 Issue: 9 Pages: 102335-102335

    • DOI

      10.1016/j.jbc.2022.102335

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06146, KAKENHI-PROJECT-22K06199, KAKENHI-PROJECT-22K06215, KAKENHI-PROJECT-17K07327, KAKENHI-PROJECT-23K24136
  • [Journal Article] TBC1D24 regulates recycling of clathrin-independent cargo proteins mediated by tubular recycling endosomes2020

    • Author(s)
      Kim Nguyen NT, Ohbayashi N, Kanaho Y, Funakoshi Y.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 528 Issue: 1 Pages: 220-226

    • DOI

      10.1016/j.bbrc.2020.05.007

    • NAID

      120007132607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07327, KAKENHI-PROJECT-19K06653, KAKENHI-PROJECT-18H02601
  • [Journal Article] Unveiling the interaction between the molecular motor Myosin Vc and the small GTPase Rab3A.2020

    • Author(s)
      Dolce LG, Ohbayashi N, Silva DFCD, Ferrari AJR, Pirolla RAS, Schwarzer ACAP, Zanphorlin LM, Cabral L, Fioramonte M, Ramos CHI, Gozzo FC, Fukuda M, Giuseppe PO, Murakami MT.
    • Journal Title

      J Proteomics.

      Volume: 212 Pages: 103549-103549

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06653
  • [Journal Article] Recent advances in understanding the molecular basis of melanogenesis in melanocytes2020

    • Author(s)
      Ohbayashi Norihiko、Fukuda Mitsunori
    • Journal Title

      F1000Research

      Volume: 9 Pages: 608-608

    • DOI

      10.12688/f1000research.24625.1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06653, KAKENHI-PROJECT-19H03220
  • [Journal Article] Unveiling the interaction between the molecular motor Myosin Vc and the small GTPase Rab3A.2020

    • Author(s)
      Dolce, L. G., Ohbayashi, N., da Silva, D. F. C., Ferrari, A. J. R., Pirolla, R. A. S., Schwarzer, A. C. de A. P., Zanphorlin, L. M., Cabral, L., Fioramonte, M., Ramos, C. H. I., Gozzo, F. C., Fukuda, M., de Giuseppe P. O. and Murakami, M. T.
    • Journal Title

      J. Proteomics

      Volume: 212 Pages: 103549-103549

    • DOI

      10.1016/j.jprot.2019.103549

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03220, KAKENHI-PROJECT-19K06653
  • [Journal Article] Cytoplasmic control of Rab family small GTPases through BAG62019

    • Author(s)
      Takahashi Toshiki、Minami Setsuya、Tsuchiya Yugo、Tajima Kazu、Sakai Natsumi、Suga Kei、Hisanaga Shin‐ichi、Ohbayashi Norihiko、Fukuda Mitsunori、Kawahara Hiroyuki
    • Journal Title

      EMBO reports

      Volume: 20 Issue: 4

    • DOI

      10.15252/embr.201846794

    • NAID

      120007127921

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06468, KAKENHI-PUBLICLY-17H05682, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16K07060, KAKENHI-PROJECT-19K06653, KAKENHI-PUBLICLY-19H05293, KAKENHI-PROJECT-17H03657
  • [Journal Article] Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP2-producing enzyme PIP5K1A2017

    • Author(s)
      Tsai Meng-Tsz、Katagiri Naohiro、Ohbayashi Norihiko、Iwasaki Kenichi、Ohkohchi Nobuhiro、Ding Shih-Torng、Kanaho Yasunori、Funakoshi Yuji
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 9438-9438

    • DOI

      10.1038/s41598-017-09633-z

    • NAID

      120007134880

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07327, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-15K07039
  • [Journal Article] Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration2017

    • Author(s)
      Lin Yueh-Chien、Ohbayashi Norihiko、Hongu Tsunaki、Katagiri Naohiro、Funakoshi Yuji、Lee Hsinyu、Kanaho Yasunori
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 11431-11431

    • DOI

      10.1038/s41598-017-11240-x

    • NAID

      120007134837

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07327, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-15K07039
  • [Journal Article] The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses2017

    • Author(s)
      Takahama Michihiro、Fukuda Mitsunori、Ohbayashi Norihiko、Kozaki Tatsuya、Misawa Takuma、Okamoto Toru、Matsuura Yoshiharu、Akira Shizuo、Saitoh Tatsuya
    • Journal Title

      Cell Reports

      Volume: 20 Issue: 12 Pages: 2944-2954

    • DOI

      10.1016/j.celrep.2017.08.085

    • NAID

      120007134819

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26713005, KAKENHI-PUBLICLY-16H01189, KAKENHI-PUBLICLY-17H05682, KAKENHI-PLANNED-17H06415, KAKENHI-PROJECT-15K07039, KAKENHI-ORGANIZER-17H06413
  • [Journal Article] C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.2017

    • Author(s)
      Aoki, Y., Manzano, R., Lee, Y., Dafinca, R., Aoki, M., Douglas, A. G. L., Varela, M. A., Sathyaprakash, C., Scaber, J., Barbagallo, P., Vader, P., Mager, I., Ezzat, K., Turner, M. R., Ito, N., Gasco, S., Ohbayashi, N., El-Andaloussi, S., Takeda, S., Fukuda, M., Talbot, K. and Wood, M. J. A.
    • Journal Title

      Brain

      Volume: 140 Issue: 4 Pages: 887-897

    • DOI

      10.1093/brain/awx024

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01198, KAKENHI-PROJECT-15H04367, KAKENHI-PROJECT-15J11847, KAKENHI-PROJECT-15K19018, KAKENHI-PUBLICLY-17H05682, KAKENHI-PROJECT-15K07039
  • [Journal Article] The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing.2017

    • Author(s)
      Miura Y, Ngo Thai Bich V, Furuya M, Hasegawa H, Takahashi S, Katagiri N, Hongu T, Funakoshi Y, Ohbayashi N, Kanaho Y.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 46649-46649

    • DOI

      10.1038/srep46649

    • NAID

      120007129142

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25430002, KAKENHI-PROJECT-16K06988, KAKENHI-PROJECT-17K07327, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-15K07039
  • [Journal Article] Rab32 subfamily small GTPases: pleiotropic Rabs in endosomal trafficking.2017

    • Author(s)
      Ohbayashi, N., Fukuda, M. and Kanaho, Y.
    • Journal Title

      J. Biochem.

      Volume: 62 Issue: 2 Pages: 65-71

    • DOI

      10.1093/jb/mvx027

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01189, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-15H04367, KAKENHI-PROJECT-15K07039
  • [Journal Article] ACAP3 regulates neurite outgrowth through its GAP activity specific to Arf6 in mouse hippocampal neurons.2016

    • Author(s)
      Miura Y, Hongu T, Yamauchi Y, Funakoshi Y, Katagiri N, Ohbayashi N, Kanaho Y.
    • Journal Title

      Biochemical Journal

      Volume: 473 Issue: 17 Pages: 2591-2602

    • DOI

      10.1042/bcj20160183

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J00701, KAKENHI-PROJECT-26440044, KAKENHI-PROJECT-15K19001, KAKENHI-PROJECT-15K07039, KAKENHI-PROJECT-16K19014
  • [Journal Article] A Varp-binding protein, RACK1, regulates dendrite outgrowth through stabilization of Varp protein in mouse melanocytes.2016

    • Author(s)
      Marubashi, S., Ohbayashi, N. and Fukuda, M.
    • Journal Title

      J. Invest. Dermatol.

      Volume: 136 Issue: 8 Pages: 1672-1680

    • DOI

      10.1016/j.jid.2016.03.034

    • NAID

      120007129451

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01198, KAKENHI-PROJECT-15H04367, KAKENHI-PROJECT-15K07039
  • [Journal Article] RUTBC1 functions as a GTPase-activating protein for Rab32/38 and regulates melanogenic enzyme trafficking in melanocytes.2016

    • Author(s)
      Marubashi, S., Shimada, H., Fukuda, M. and Ohbayashi, N.
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Issue: 3 Pages: 1427-1440

    • DOI

      10.1074/jbc.m115.684043

    • NAID

      120007128493

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01198, KAKENHI-PROJECT-15H04367, KAKENHI-PROJECT-15K07039
  • [Journal Article] Pathological functions of the small GTPase Arf6 in cancer progression: Tumor angiogenesis and metastasis2016

    • Author(s)
      Hongu T, Yamauchi Y, Funakoshi Y, Katagiri N, Ohbayashi N, Kanaho Y
    • Journal Title

      Small GTPases

      Volume: 0 Issue: 2 Pages: 1-7

    • DOI

      10.1080/21541248.2016.1154640

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19001, KAKENHI-PROJECT-14J00701, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-15K07039
  • [Journal Article] Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes.2015

    • Author(s)
      Yatsu, A., Shimada, H., Ohbayashi, N. and Fukuda, M.
    • Journal Title

      Biol. Open

      Volume: 4 Issue: 3 Pages: 267-275

    • DOI

      10.1242/bio.201411114

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-15K07039
  • [Journal Article] Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis.2015

    • Author(s)
      Okada R, Yamauchi Y, Hongu T, Funakoshi Y, Ohbayashi N, Hasegawa H, Kanaho Y
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 14919-14919

    • DOI

      10.1038/srep14919

    • NAID

      120007135937

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07039, KAKENHI-PROJECT-25430002, KAKENHI-PROJECT-26440044, KAKENHI-PROJECT-15K19001, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-14J00701
  • [Journal Article] Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP2015

    • Author(s)
      Ishida, M., Ohbayashi, N. and Fukuda, M
    • Journal Title

      Sci. Rep.

      Volume: 5 Issue: 1 Pages: 8238-8238

    • DOI

      10.1038/srep08238

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J02630, KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-15K07039
  • [Journal Article] Measurement of Rab35 Activity with the GTP-Rab35 Trapper RBD35.2015

    • Author(s)
      Kobayashi H, Etoh K, Marubashi S, Ohbayashi N, Fukuda M.
    • Journal Title

      Methods Mol Biol

      Volume: 1298 Pages: 207-216

    • DOI

      10.1007/978-1-4939-2569-8_18

    • ISBN
      9781493925681, 9781493925698
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J10075, KAKENHI-PROJECT-15K07039, KAKENHI-PROJECT-15H04367
  • [Journal Article] Atmospheric Scanning Electron Microscope System with an Open Sample Chamber: Configuration and Applications2014

    • Author(s)
      H.Nishiyama, M.Koizumi, K.Ogawa, S.Kitamura, Y.Konyuba, Y.Watanabe, N.Ohbayashi, M.Fukuda, M.Suga and C.Sato
    • Journal Title

      Ultramicroscopy

      Volume: 147 Pages: 86-97

    • DOI

      10.1016/j.ultramic.2014.06.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22121004, KAKENHI-PROJECT-24570206
  • [Journal Article] Rab35 promotes the recruitment of Rab8, Rab13, and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth.2014

    • Author(s)
      Kobayashi H, Etoh K, Ohbayashi N, Fukuda M
    • Journal Title

      Biol Open

      Volume: 3 Issue: 9 Pages: 803-814

    • DOI

      10.1242/bio.20148771

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J10075, KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-24570206
  • [Journal Article] The GTPase-deficient Rab27A(Q78L) Mutant Inhibits Melanosome Transport in Melanocytes through Trapping of Slac2-a/melanophilin in their Cytosol: Development of a Novel Melanosome-targeting Tag2014

    • Author(s)
      Ishida, M., Arai, SP., Ohbayashi, N. and Fukuda, M
    • Journal Title

      J. Biol. Chem.

      Volume: 289 Issue: 16 Pages: 11059-11067

    • DOI

      10.1074/jbc.m114.552281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J02630, KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-24570206
  • [Journal Article] Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma membrane recycling.2014

    • Author(s)
      McGough, I. J., Steinberg, F., Gallon, M., Yatsu, A., Ohbayashi, N., Heesom, K., Fukuda, M. and Cullen, P. J.
    • Journal Title

      J. Cell Sci.

      Volume: 127 Pages: 4940-4953

    • DOI

      10.1242/jcs.156299

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-24570206
  • [Journal Article] Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis.2014

    • Author(s)
      Azouz, N.P., Zur, N., Efergan, A., Ohbayashi, N., Fukuda, M., Amihai, D., Hammel, I., Rothenberg, M.E., and Sagi-Eisenberg, R.
    • Journal Title

      J. Immunol.

      Volume: 192 Issue: 9 Pages: 4043-4053

    • DOI

      10.4049/jimmunol.1302196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Journal Article] Rab GTPases and their roles in membrane traffic.2013

    • Author(s)
      大林典彦、福田光則
    • Journal Title

      Leading Author's

      Volume: 2 Pages: e006

    • DOI

      10.7875/leading.author.2.e006

    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-24570206
  • [Journal Article] Syntaxin-3 is required for melanosomal localization of Tyrp1 in melanocytes2013

    • Author(s)
      Yatsu, A., Ohbayashi, N., Tamura, K.& Fukuda M
    • Journal Title

      J. Invest. Dermatol

      Volume: (in press) Issue: 9 Pages: 2237-2246

    • DOI

      10.1038/jid.2013.156

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-24570206
  • [Journal Article] The GTPase Rab37 Participates in the Control of Insulin Exocytosis.2013

    • Author(s)
      Ljubicic, S., Bezzi, P., Brajkovic, S., Nesca, V., Guay, C., Ohbayashi, N., Fukuda, M., Abderrhamani, A., and Regazzi, R.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 6 Pages: e68255-e68255

    • DOI

      10.1371/journal.pone.0068255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Journal Article] The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes2012

    • Author(s)
      Ohbayashi, N., Yatsu, A., Tamura, K., Fukuda, M.
    • Journal Title

      Mol.Biol.Cell

      Volume: 23 Issue: 4 Pages: 669-678

    • DOI

      10.1091/mbc.e11-04-0324

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-24570206
  • [Journal Article] The Rab interacting lysosomal protein (RILP)homology domain functions as a novel effector domain for small GTPase Rab36 : Rab36 regulates retrograde melanosome transport in melanocytes.2012

    • Author(s)
      Matsui, T., Ohbayashi, N. and Fukuda, M.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 287 Issue: 34 Pages: 28619-28631

    • DOI

      10.1074/jbc.m112.370544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07349, KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-24570206, KAKENHI-PROJECT-24657125
  • [Journal Article] Role of Rab family GTPases and their effectors in melanosomal logistics2012

    • Author(s)
      Ohbayashi, N. & Fukuda. M
    • Journal Title

      J. Biochem

      Volume: 151 Issue: 4 Pages: 343-351

    • DOI

      10.1093/jb/mvs009

    • NAID

      10031166073

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-24570206
  • [Journal Article] Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p 150Glued complex2012

    • Author(s)
      Ohbayashi, N., Maruta, Y, Ishida, M .& Fukuda, M
    • Journal Title

      J. Cell. Sci

      Volume: 125 Pages: 1508-1518

    • DOI

      10.1242/jcs.094185

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-24570206
  • [Journal Article] Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes2012

    • Author(s)
      Ishida, M., Ohbayashi, N., Mamta, Y, Ebata, Y & Fukuda. M
    • Journal Title

      J. Cell. Sci

      Volume: 125 Pages: 5177-5187

    • DOI

      10.1242/jcs.109314

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-24570206
  • [Journal Article] Genome-wide Investigation of the Rab Binding Activity of RUN Domains: Development of a Novel Tool that Specifically Traps GTP-Rab352011

    • Author(s)
      Fukuda, M., Kobayashi, H., Ishibashi, K., Ohbayashi, N.
    • Journal Title

      Cell Struct. Funct.

      Volume: 36 Issue: 2 Pages: 155-170

    • DOI

      10.1247/csf.11001

    • NAID

      130004053880

    • ISSN
      0386-7196, 1347-3700
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06981, KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-21370087, KAKENHI-PROJECT-22770183
  • [Journal Article] he recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking2011

    • Author(s)
      Beaumont, K. A., Hamilton, N. A., Moores, M. T., Brown, D. L., Ohbayashi, N., Cairncross, O., Cook, A. L., Smith, A. G., Misaki, R., Fukuda, M., Taguchi, T., Sturm, R. A., and Stow, J. L.
    • Journal Title

      Traffic

      Volume: 12 Pages: 627-643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Journal Article] The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking2011

    • Author(s)
      Beaumont, K.A., et al
    • Journal Title

      Traffic

      Volume: 12 Issue: 5 Pages: 627-643

    • DOI

      10.1111/j.1600-0854.2011.01172.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-22770183
  • [Journal Article] Structure-function analysis of VP S9-ankyrin-repeat protein(Varp)in the trafficking of tyrosinase-related protein 1 in melanocytes2011

    • Author(s)
      Tamura, K., Ohbayashi, N., Ishibashi, K. & Fukuda, M
    • Journal Title

      J. Boil. Chem

      Volume: 286 Issue: 9 Pages: 7507-7521

    • DOI

      10.1074/jbc.m110.191205

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-22770183
  • [Journal Article] Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.2010

    • Author(s)
      Kanno, E., Ishibashi, K., Kobayashi, H., Matsui, T., Ohbayashi, N., Fukuda, M.
    • Journal Title

      Traffic

      Volume: 11 Pages: 491-507

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Journal Article] Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 22010

    • Author(s)
      Ohbayashi, N., Mamishi, S., Ishibashi, K., Maruta, Y., Pourakbari, B., Tamizifar, B., Mohammadpour, M., Fukuda, M., and Parvaneh, N.
    • Journal Title

      Pigment Cell Melanoma Res

      Volume: 23 Pages: 365-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Journal Article] Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2.2010

    • Author(s)
      Ohbayashi, N., Mamishi, S., Ishibashi, K., Maruta, Y., Pourakbari, B., Tamizifar, B., Mohammadpour, M., Fukuda, M., Parvaneh, N.
    • Journal Title

      Pigment Cell Melanoma Res

      Volume: 23 Pages: 365-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Journal Article] Comprehensive screening for novel Rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs2010

    • Author(s)
      Kanno, E., Ishibashi, K., Kobayashi, H., Matsui, T., Ohbayashi, N. & Fukuda, M
    • Journal Title

      Traffic

      Volume: 11 Issue: 4 Pages: 491-507

    • DOI

      10.1111/j.1600-0854.2010.01038.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113006, KAKENHI-PROJECT-22770183
  • [Journal Article] STAP-2 negatively regulates both canonical and non-canonical NF-kB activation induced by Epstein-Barr virus-derived LMP1.2008

    • Author(s)
      Ikeda O., Y. Sekine, T. Yasui, K. Oritani, K. Sugiyma, R. Muromoto, N. Ohbayashi, A. Yoshimura, T. Matsuda
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 5027-5042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] Physical and functional interactions between ZIP kinase and UbcH52008

    • Author(s)
      Ohbayashi, N., et.al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 372

      Pages: 708-712

    • NAID

      120000952720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] Physical and functional interactions between STAT3 and KAP12008

    • Author(s)
      Tsuruma R., Ohbayashi N., Kamitani S., Ikeda O., Sato N., Muromoto R., Sekine Y., Oritani K., T. Matsuda
    • Journal Title

      Oncogene 27

      Pages: 3054-3059

    • NAID

      120000947432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction2008

    • Author(s)
      Ohbayashi N., Kawakami S., Muromoto R., Togi S., Ikeda O., Kamitani S., Sekine Y., Honjoh T., T. Matsuda
    • Journal Title

      Biochem. Biophys. Res. Commun. 371

      Pages: 823-828

    • NAID

      120000952714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] The IL-6 family of cytokines modulates STAT3 activation by desu moylation of PML through SENP1 induction2008

    • Author(s)
      Ohbayashi, N., et.al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 371

      Pages: 823-828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression2008

    • Author(s)
      Kamitani S., Ohbayashi N., Ikeda O., Togi S., Muromoto R., Sekine Y., Ohta K., Ishiyama H., T. Matsuda
    • Journal Title

      Biochem. Biophys. Res. Commun. 370

      Pages: 366-370

    • NAID

      120000952715

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] An RNA biding protein, Y14 interacts with and modulates STAT3 activation2008

    • Author(s)
      Ohbayashi N., N. Taira S. Kawakami S. Togi N. Sato O. Ikeda S. Kamitani R. Muromoto Y. Sekine, T. Matsuda
    • Journal Title

      Biochem. Biophys. Res. Commun. 372

      Pages: 475-479

    • NAID

      120000952719

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] An RNA biding protein, Y14 interacts with and modulates STAT3 a ctivation2008

    • Author(s)
      Ohbayashi, N., et.al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 372

      Pages: 475-479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] Enhanced c-Fms/M-CSF receptor signaling and wound-healing process in bone marrow-derived macrophages of STAP-2 deficient mice2008

    • Author(s)
      Ikeda O., Y. Sekine, R. Muromoto, N. Ohbayashi, A. Yoshimura, T. Matsuda
    • Journal Title

      Biol. Pharm. Bull. 31

      Pages: 1790-1793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] Physical and functional interactions between ZIP kinase and UbcH52008

    • Author(s)
      Ohbayashi N., K. Okada, S. Kawakami, S. Togi, N. Sato, O. Ikeda, S. Kamitani, R. Muromoto, Y. Sekine, T. Kawai, S. Akira, T. Matsuda
    • Journal Title

      Biochem. Biophys. Res. Commun. 372

      Pages: 708-712

    • NAID

      120000952720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390017
  • [Journal Article] LIF- and IL-6-induced acetylation of STAT3 at Lys-685 through PI3K/Akt activation2007

    • Author(s)
      Ohbayashi, N., et. al.
    • Journal Title

      Biol. Pharm. Bull. 30

      Pages: 1860-1864

    • NAID

      110006436364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659036
  • [Journal Article] STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells.2007

    • Author(s)
      Ikeda, 0., Sekine, Y., Kakisaka, M., Tsuji, S., Muromoto, R., Ohbayashi, N., Oritani, K., Yoshimura A., and T. Matsuda
    • Journal Title

      Biochem. Biophys. Res. Commun 358

      Pages: 931-937

    • NAID

      120000969065

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390017
  • [Journal Article] LIF-and IL-6-induced acetylation of STAT3 at Lys-685 through PI3K/Akt activation2007

    • Author(s)
      Ohbayashi, N., et. al.
    • Journal Title

      Biological & pharmaceutical bulletin 30

      Pages: 1860-1864

    • NAID

      110006436364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18791032
  • [Journal Article] STAP-2 regulates integrin-mediated T-cell adhesion through protein degradation of FAK.2007

    • Author(s)
      Sekine, Y., Tsuji, S., Ikeda, 0., Sugiyma, K., Oritani, K., Shimoda, K., Muromoto, R., Ohbayashi, N., Yoshimura, A., and T. Matsuda
    • Journal Title

      J. Immunol 179

      Pages: 2397-2407

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390017
  • [Presentation] 脱ユビキチン化酵素TRE17/USP6による膜タンパク質の輸送制御を介した腫瘍細胞の浸潤促進機構脱ユビキチン化酵素TRE17/USP6による膜タンパク質の輸送制御を介した腫瘍細胞の浸潤促進機構2022

    • Author(s)
      小倉由希乃、川口敦史、船越祐司、大林典彦、金保安則
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06215
  • [Presentation] BAG6によるメラニン合成酵素輸送因子Rab32/38の新規制御機構2021

    • Author(s)
      大林典彦、田島佳寿,高橋俊樹,福田光則,川原裕之
    • Organizer
      第30回日本色素細胞学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K06653
  • [Presentation] 脱ユビキチン化酵素TRE17/USP6は、膜蛋白質の輸送を介して癌細胞浸潤能を亢進する.2019

    • Author(s)
      Kanaho Yasunori; 船越祐司; 小倉由希乃; 大林典彦
    • Organizer
      第42回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06653
  • [Presentation] Ubiquitin-specific protease TRE17/USP6 promotes cancer cell invasion through the regulation of CD147 recycling.2019

    • Author(s)
      Kanaho Yasunori; 船越祐司; Nguyen Nguyen Thi Kim; 大林典彦
    • Organizer
      第42回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06653
  • [Presentation] 小胞輸送が司るメラノソーム形成機構2019

    • Author(s)
      大林典彦
    • Organizer
      第29回日本色素細胞学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K06653
  • [Presentation] A Varp-binding protein, RACK1, regulates dendrite outgrowth through stabilization of Varp protein in melanocytes.2017

    • Author(s)
      Soujiro Marubashi, Norihiko Ohbayashi and Mitsunori Fukuda
    • Organizer
      The 2017 Japan-NIH joint Symposium on Advances in Biomedical Research and Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] 新規Varp結合分子・RACK1はVarpの安定化を介してメラノサイトのデンドライト伸長に関与する2015

    • Author(s)
      丸橋総史郎、大林典彦、福田光則
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸市、神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] 癌細胞浸潤における Arf6 GTPase 活性化因子 ARAP3 の機能解析2015

    • Author(s)
      山内庸平、 本宮綱記、山口英樹、船越祐司、大林典彦、金保安則
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸市、神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] The Arf6-specific GTPase-activating protein ARAP3 regulates breast cancer cell invasion.2015

    • Author(s)
      Yohei Y, Hongu T, Yamaguchi H, Funakoshi Y, Ohbayashi N, Kanaho Y
    • Organizer
      Tsukuba Global Science Week 2015
    • Place of Presentation
      Tsukuba, Japan
    • Year and Date
      2015-09-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] Varpの新規結合分子の探索とメラノサイトのデンドライト形成への関与2015

    • Author(s)
      丸橋総史郎、大林典彦、福田光則
    • Organizer
      日本生化学会東北支部 第81回例会
    • Place of Presentation
      仙台市、東北大学片平さくらホール
    • Year and Date
      2015-05-09
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] The molecular mechanisms of anterograde melanosome transport on microtubules in mammalian melanocytes.2015

    • Author(s)
      Ishida M, Ohbayashi N, Fukuda M
    • Organizer
      The 2015 Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      San Diego, CA
    • Year and Date
      2015-12-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] ACAP3はArf6特異的なGAPとして働き、マウス海馬神経細胞の神経突起伸長を制御する2015

    • Author(s)
      三浦悠樹、本宮綱記、船越祐司、大林典彦、金保安則
    • Organizer
      第14回生命科学研究会
    • Place of Presentation
      三浦市、三浦市民ホール
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] RUTBC1はRab32/38の不活性化を通してメラニン合成酵素の輸送を調節する2015

    • Author(s)
      大林典彦、丸橋総史郎、福田光則
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸市、神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07039
  • [Presentation] Syntaxin-3はメラニン合成酵素のメラノソームへの輸送を制御する2013

    • Author(s)
      谷津彩香、大林典彦、田村可南子、福田光則
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Presentation] 常時活性化型Rab27A変異体によるメラノソーム輸送阻害の原因を探る~メラノレギュリン分子を利用した新たなメラノソーム局在化ツールの開発~2013

    • Author(s)
      荒井沙希、石田森衛、大林典彦、福田光則
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Presentation] メラノソームの微小管輸送におけるRab small GTPaseの役割2012

    • Author(s)
      大林典彦
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Presentation] メラノサイトの樹状突起伸長におけるVarpの役割2012

    • Author(s)
      谷津彩香、大林典彦、田村可南子、福田光則
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Presentation] Rab1Aはメラノソームの微小管順行性輸送を制御する2012

    • Author(s)
      石田森衛、大林典彦、丸田優人、江幡由佳、福田光則
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Presentation] Varp-Rab32/38複合体のメラノサイトにおける生理的意義の解明2010

    • Author(s)
      田村可南子、大林典彦、石橋弘太郎、福田光則
    • Organizer
      新学術領域研究「細胞内ロジスティクス」班会議
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-30
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Presentation] Varpは新規Rab32/38エフェクターとしてメラノソーム成熟に関与する2010

    • Author(s)
      大林典彦、田村可南子、石橋弘太郎、福田光則
    • Organizer
      日本分子生物学会年会・日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Presentation] Varpは新規Rab32/38エフェクターとしてメラノソーム成熟に関与する2010

    • Author(s)
      大林典彦、田村可奈子、石橋弘太郎、福田光則
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Presentation] Rab36はダイニン・ダイナクチン複合体依存的にリソソームの核周辺への凝集を引き起こす2010

    • Author(s)
      松井貴英、大林典彦、丸田優人、伊藤敬、福田光則
    • Organizer
      日本細胞生物学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Presentation] Rab36はダイニン・ダイナクチン複合体依存的にリソソームの核周辺への凝集を引き起こす2010

    • Author(s)
      松井貴英、大林典彦、丸田優人、伊藤敬、福田光則
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22770183
  • [Presentation] 常時活性化型Rab27A変異体はエフェクター分子であるSlac2-aを細胞質でトラップすることによってメラノソーム輸送を阻害する

    • Author(s)
      荒井沙希、石田森衛、大林典彦、福田光
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24570206
  • [Presentation] Varpの新規結合タンパク質・Rab40CはメラノサイトにおいてVarpのプロテアソーム依存的な分解を促進する

    • Author(s)
      島田光、谷津彩香、大林典彦、福田光則
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24570206
  • 1.  MATSUDA Tadashi (20212219)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 2.  SEKINE Yuichi (20396295)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 3.  MUROMOTO Ryuta (30455597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 4.  NANBO Asuka (60359487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  FUNAKOSHI Yuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 6.  SAITOH Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  HASEGAWA Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  佐藤 主税
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  福田 光則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 14 results
  • 10.  須賀 圭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  本宮 綱記
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  金保 安則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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