Ono Ryoichi 小埜良一

… Alternative Names

ONO Ryoichi 小埜良一

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Researcher Number	40422414
Other IDs
Affiliation (Current)	2025: 三重大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 三重大学, 医学系研究科, 准教授 2016 – 2017: 三重大学, 医学系研究科, 講師 2016: 三重大学, 大学院医学系研究科, 講師 2012 – 2015: 三重大学, 医学(系)研究科(研究院), 講師 2014: 三重大学, 大学院医学系研究科, 講師 … More 2009 – 2012: Mie University, 大学院・医学系研究科, 講師 2007: Mie University, Graduate School of Medicine, Assistant Professor 2006: 東大, 医科学研究所 Less
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Pediatrics Except Principal Investigator Pediatrics / Hematology
Keywords	Principal Investigator 白血病 / 造血器腫瘍 / DNAメチル化 / エピゲノム / micro RNA / MLL / マイクロRNA Except Principal Investigator MLL / 白血病幹細胞 / Hox … More / Ras / MLL-ENL / 白血病 / PLZF / 乳児白血病 / 白血病モデルマウス / 自己複製 / EYA2 / retroviral vector / mouse bone marrow transplantation / infant leukemia / 11q23 chromosomal translocation / leukemic stem cell / STAT5 / MAPK / Raf / 白血病肝細胞 / レトロウイルスベクター / マウス骨髄移植 / 11q23染色体転座 / マウスモデル / ＭＬＬ－ＥＮＬ / ＭＬＬ / 造血幹細胞 / がん幹細胞 / 小児血液学 Less

染色体11q23転座型難治性白血病における新たなエピゲノム関連分子機構の解明Principal Investigator
- Principal Investigator
  
  小埜良一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Mie University
Integrated analysis of the molecular basis of leukemia stem cells using a mouse model inducibly developing leukemiaPrincipal Investigator
- Principal Investigator
  
  Ono Ryoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Mie University
Integrative understanding of the functional role of DNA demethylation-associated molecule in the process of leukemic initiationPrincipal Investigator
- Principal Investigator
  
  Ono Ryoichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Mie University
Novel molecular mechanism of maintenance of stemness through a DNA methylation regulator in normal and malignant hematopoiesisPrincipal Investigator
- Principal Investigator
  
  Ono Ryoichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Mie University
Molecular mechanism of stem cell leukemogenesis and regulation of hematopoietic cell growth
- Principal Investigator
  
  Nosaka Tetsuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
Analysis of molecular mechanism in leukemogenesis through an epigenome regulatorPrincipal Investigator
- Principal Investigator
  
  ONO RYOICHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Mie University
Model for generation of leukemic stem cells: spatio-temporal properties in pathogenesis
- Principal Investigator
  
  NOSAKA Tetsuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
Molecular mechanism of MLL-related leukemogenesis in a mouse modelfor generation of cancer stem cells
- Principal Investigator
  
  NOSAKA Tetsuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
Novel therapeutic strategy on analysis of molecular mechanism through micro RNA in refractory leukemiaPrincipal Investigator
- Principal Investigator
  
  ONO Ryoichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Mie University
11q23転座型白血病の発症機構における白血病幹細胞の分子基盤の解析Principal Investigator
- Principal Investigator
  
  小埜良一
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Analysis on the molecular mechanisms for the self renewal of the leukemic stem cells and for the leukemcgenesis
- Principal Investigator
  
  NOSAKA Tetsuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Mie University

[Journal Article] Bahcc1 is critical for the aberrant epigenetic program in a mouse model of MLL-ENL-mediated leukemia.2024
- Author(s)
  Nakamura A, Masuya M, Shinmei M, Tawara I, Nosaka T, Ono R.
- Journal Title
  
  Blood Advances
  
  Volume: - Issue: 9 Pages: 2193-2206
- DOI
  10.1182/bloodadvances.2023011320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08411
[Journal Article] Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis.2022
- Author(s)
  D'Alessandro-Gabazza CN, Yasuma T, Kobayashi T, Toda M, Abdel-Hamid AM, Fujimoto H, Hataji O, Nakahara H, Takeshita A, Nishihama K, Okano T, Saiki H, Okano Y, Tomaru A, D'Alessandro VF, Shiraishi M, Mizoguchi A, Ono R, Ohtsuka J, Fukumura M, Nosaka T, et al. & Gabazza EC
- Journal Title
  
  Nat Commun
  
  Volume: 13 Issue: 1 Pages: 1558-1558
- DOI
  10.1038/s41467-022-29064-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03529, KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K08256, KAKENHI-PROJECT-21K08411, KAKENHI-PROJECT-20K21614, KAKENHI-PROJECT-21K08203, KAKENHI-PROJECT-21K16185, KAKENHI-PROJECT-21K16116, KAKENHI-PROJECT-21K16160
[Journal Article] Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2.2021
- Author(s)
  Ohtsuka J, Imai M, Fukumura M, Maeda M, Eguchi A, Ono R, Maemura T, Ito M, Yamayoshi S, Kataoka Y, Kawaoka Y, Nosaka T
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 12 Pages: 103379-103379
- DOI
  10.1016/j.isci.2021.103379
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03529, KAKENHI-PROJECT-21K08411, KAKENHI-PROJECT-20K21614
[Journal Article] Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models.2021
- Author(s)
  Ono R, Masuya M, Inoue N, Shinmei M, Ishii S, Maegawa Y, Maharjan BD, Katayama N, Nosaka T.
- Journal Title
  
  PLosONE
  
  Volume: 16 Issue: 3 Pages: e0248425-e0248425
- DOI
  10.1371/journal.pone.0248425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21614, KAKENHI-PROJECT-18H02453, KAKENHI-PROJECT-20H03529, KAKENHI-PROJECT-18K08352, KAKENHI-PROJECT-19K08442
[Journal Article] Genetic polymorphisms and vincristine-induced peripheral neuropathy in patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone therapy.2020
- Author(s)
  Sawaki A, Miyazaki K, Yamaguchi M, Takeuchi T, Kobayashi K, Imai H, Tawara I, Ono R, Nosaka T, Katayama N.
- Journal Title
  
  Int J Hematol
  
  Volume: 111 Issue: 5 Pages: 686-691
- DOI
  10.1007/s12185-020-02832-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04227, KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-17K19652, KAKENHI-PROJECT-20K21614, KAKENHI-PROJECT-20H03529, KAKENHI-PROJECT-18K08352
[Journal Article] Eya2 is critical for E2A-HLF-mediated immortalization of mouse hematopoietic stem/progenitor cells.2019
- Author(s)
  Maharjan BD, Ono R, Nosaka T.
- Journal Title
  
  Int J Oncol
  
  Volume: 54 Pages: 981-990
- DOI
  10.3892/ijo.2019.4673
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19652, KAKENHI-PROJECT-17H04227, KAKENHI-PROJECT-18K08352
[Journal Article] Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy.2017
- Author(s)
  Yamanaka K, Nakanishi T, Isono K, Hasegawa C, Inada Y, Mizutani K, Matsushima Y, Okada K, Mabuchi T, Kondo M, Yamagiwa A, Kakeda M, Habe K, Nosaka T, Gabazza EC, Yamazaki H, Mizutani H, Kawano M.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 139 Issue: 2 Pages: 682-686
- DOI
  10.1016/j.jaci.2016.05.044
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293247, KAKENHI-PROJECT-15K09170, KAKENHI-PROJECT-26461690, KAKENHI-PROJECT-17K19652, KAKENHI-PROJECT-17K16336, KAKENHI-PROJECT-17H04227, KAKENHI-PROJECT-15K15605, KAKENHI-PROJECT-17K10241, KAKENHI-PROJECT-17K10208
[Journal Article] MYD88, CD79B, and CARD11 gene mutations in CD5-positive diffuse large B-cell lymphoma.2017
- Author(s)
  Takeuchi, T, Yamaguchi M, Kobayashi K, Miyazaki K, Tawara I, Imai H, Ono R, Nosaka T, Tanaka K, Katayama N.
- Journal Title
  
  Cancer
  
  Volume: 123 Issue: 7 Pages: 1166-1173
- DOI
  10.1002/cncr.30404
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293247, KAKENHI-PROJECT-17K19652, KAKENHI-PROJECT-17H04227, KAKENHI-PROJECT-15K09452
[Journal Article] Eya2, a target activated by Plzf, is critical for PLZF-RARA-induced leukemogenesis.2017
- Author(s)
  Ono R, Masuya M, Ishii S, Katayama N, Nosaka T.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 印刷中 Issue: 13
- DOI
  10.1128/mcb.00585-16
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293247, KAKENHI-PROJECT-16K09307, KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-17K19652, KAKENHI-PROJECT-17H04227, KAKENHI-PROJECT-15K09452
[Journal Article] Expressions of SH3BP5, LMO3, and SNAP25 in diffuse large B-cell lymphoma cells and their association with clinical features.2016
- Author(s)
  Kobayashi K, Yamaguchi M, Miyazaki K, Imai H, Yokoe K, Ono R, Nosaka T, Katayama N.
- Journal Title
  
  Cancer Med
  
  Volume: 5 Issue: 8 Pages: 1802-1809
- DOI
  10.1002/cam4.753
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293247, KAKENHI-PROJECT-15K09452
[Journal Article] Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD).2016
- Author(s)
  Kitamura T, Watanabe-Okochi N, Enomoto Y, Nakahara F, Oki T, Komeno Y, Kato N, Doki N, Uchida T, Kagiyama Y, Togami K, Kawabata KC, Nishimura K, Hayashi Y, Nagase R, Saika M, Fukushima T, Asada S, Fujino T, Izawa Y, Horikawa S, Fukuyama T, Tanaka Y, Ono R, Goyama S, Nosaka T, Kitaura J, Inoue D
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 159 Issue: 1 Pages: 17-25
- DOI
  10.1093/jb/mvv114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09452, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-13J09414, KAKENHI-PROJECT-26670465, KAKENHI-PROJECT-26293247, KAKENHI-PROJECT-16H06276
[Journal Article] Cynomolgus monkey induced pluripotent stem cells established by using exogenous genes derived from the same monkey species.2013
- Author(s)
  Shimozawa N, Ono R, Shimada M, Shibata H, Takahashi I, Inada H, Takada T, Nosaka T, Yasutomi Y.
- Journal Title
  
  Differentiation
  
  Volume: 85 Issue: 4-5 Pages: 131-139
- DOI
  10.1016/j.diff.2013.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659494, KAKENHI-PUBLICLY-25118712, KAKENHI-PROJECT-25670225
[Journal Article] Manipulation of human early T lymphopoiesis by coculture on human bone marrow stromal cells: Potential utility for adoptive immunotherapy2013
- Author(s)
  Liu B, Ohishi K, Orito Y,N a k a mo r i Y, Nishikawa H, Ino K,Suzuki K, Matsumoto T,Masuya M,Hamada H, Mineno J, Ono R, Nosaka T, Shiku H, Katayama N.
- Journal Title
  
  Exp Hematol
  
  Volume: - Issue: 4 Pages: 367-376
- DOI
  10.1016/j.exphem.2012.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390206, KAKENHI-PROJECT-23300354, KAKENHI-PROJECT-24591390, KAKENHI-PROJECT-24659494, KAKENHI-PUBLICLY-25118712, KAKENHI-PROJECT-25460951, KAKENHI-PROJECT-25461413, KAKENHI-PROJECT-25461447
[Journal Article] Plzf drives MLL-fusion-mediated leukemogenesis specifically in long-term hematopoietic stem cells.2013
- Author(s)
  Ono, R
- Journal Title
  
  Blood
  
  Volume: 122 Issue: 7 Pages: 1271-1283
- DOI
  10.1182/blood-2012-09-456665
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24591390, KAKENHI-PROJECT-24659494, KAKENHI-PUBLICLY-25118712, KAKENHI-PROJECT-25460951, KAKENHI-PROJECT-25461413
[Journal Article] Cynomolgus monkey induced pluripotent stem cells established by using exogenous genes derived from the same monkey species.2013
- Author(s)
  Shimozawa N, Ono R, Shimada M, Shibata H, Takahashi I, Inada H, Takada T, Nosaka T, Yasutomi Y.
- Journal Title
  
  Differentiation
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390206
[Journal Article] IKAROS isoform 6 enhances BCR-ABL1-mediated proliferation of human CD34+ hematopoietic cells on stromal cells2012
- Author(s)
  Suzuki K, et al
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 53-62
- DOI
  10.3892/ijo.2011.1192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591200, KAKENHI-PROJECT-22390206, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23501309
[Journal Article] IKAROS isoform 6 enhances BCR-ABL1-mediated proliferation of human CD34+ hematopoietic cells on stromal cells2012
- Author(s)
  Suzuki K, Ono R, Ohishi K, Masuya M, Kataoka I, Liu B, Nakamori Y, Ino K, Monma F, Hamada H, Kitamura T, Katayama N, Nosaka T
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 53-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] Expression of ADAMTS4 in Ewing's sarcoma2010
- Author(s)
  Minobe K, Ono R, Matsumine A, Shibata-Minoshima F, Izawa K, Oki T, Kitaura J, Iino T, Takita J, Iwamoto S, Hori H, Komada Y, Uchida A, Hayashi Y, Kitamura T, Nosaka T
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 569-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] Expression of ADAMTS4 in Ewing' s sarcoma.2010
- Author(s)
  Minobe K, Ono R, Matsumine A, Shibata-Minoshima F, Izawa K, Oki T, Kitaura J, Iino T, Takita J, Iwamoto S, Hori H, Komada Y, Uchida A, Hayashi Y, Kitamura T, Nosaka T.
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 569-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390206
[Journal Article] Expression of ADAMTS4 in Ewing's sarcoma2010
- Author(s)
  Minobe K, Ono R, Matsumine A, Shibata-Minoshima F, Izawa K, Oki T, Kitaura J, Iino T, Takita J, Iwamoto S, Hori H, Komada Y, Uchida A, Hayashi Y, Kitamura T, Nosaka T
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 569-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390206
[Journal Article] Expression of ADAMTS4 in Ewing's sarcoma.2010
- Author(s)
  Minobe K, Ono R, et al.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 37 Pages: 569-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] MLL融合遺伝子による白血病発症機構2010
- Author(s)
  野阪哲哉、小埜良一
- Journal Title
  
  血液・腫瘍科
  
  Volume: 61 Pages: 217-223
- NAID
  40019064212
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] MLL融合遺伝子による白血病発症機構2010
- Author(s)
  野阪哲哉、小埜良一
- Journal Title
  
  血液・腫瘍科
  
  Volume: 61(2) Pages: 217-223
- NAID
  40019064212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390206
[Journal Article] Mixed-lineage-leukemia(MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation2009
- Author(s)
  Ono R, Kumagai H, Nakajima H, Hishiya A, Taki T, Horikawa K, Takatsu K, Satoh T, Hayashi Y, Kitamura T, Nosaka T
- Journal Title
  
  Leukemia
  
  Volume: 23 Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation2009
- Author(s)
  Ono RR, et al.
- Journal Title
  
  Leukemia 23
  
  Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] Possible involvement of RasGRP4 in leukemogenesis2009
- Author(s)
  Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, Harada Y, Harada H, Hayashi Y, Nakajima H, Nosaka T, Kitaura J, Kitamura T
- Journal Title
  
  Int J Hematol
  
  Volume: 89 Pages: 470-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] Possible involvement of RasGRP4 in leukemogenesis.2009
- Author(s)
  Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, et al.
- Journal Title
  
  International Journal of Hematology 89
  
  Pages: 470-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression.2009
- Author(s)
  Jin G, Matsushita H, Asai S, Tsukamoto H, Ono R, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 390
  
  Pages: 1001-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression2009
- Author(s)
  Jin G, Matsushita H, Asai S, Tsukamoto H, Ono R, Nosaka T, Yahata T, Takahashi S, Miyachi H
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 390 Pages: 1001-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790911
[Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model.2008
- Author(s)
  Watanabe-Okochi N, Kitaura J, Ono R, Harada H, Harada Y, Komeno Y, Nakajima H, Nosaka T, Inaba T, Kitamura T.
- Journal Title
  
  Blood 111
  
  Pages: 4297-4308
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Identification of leukemia-related gene alterations: Molecular pathogenesis of leukemia, myeloproliferative disorders(MPD), and myelodysplastic syndromes(MDS).2008
- Author(s)
  Kitamura T, Oki T, Watanabe-Okochi N, Komeno Y, Kato N, Yuji K, Ono RNakajima H, Tojo A, Nosaka T, Kitaura J.
- Journal Title
  
  Blood Cells, Molecules and Diseases. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model.2008
- Author(s)
  Watanabe-Okochi N, Kitaura J, Ono R, Harada H, Harada Y, Komeno Y, Nakajima H, Nosaka T, Inaba T, Kitamura T.
- Journal Title
  
  Blood (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model2008
- Author(s)
  Watanabe-Okochi, N. kitaura, J. Ono, R. Harada, H. Harada, Y. Komeno, Y. Nakajima, H. Nosaka, T. Inaba, T. Kitamura, T
- Journal Title
  
  Blood 111
  
  Pages: 4297-4308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD.2007
- Author(s)
  Lu Y, Kitaura J, Oki T, Komeno Y, Ozaki K, Kiyono M, Kumagai H, Nakajima H, Nosaka T, Aburatani H, Kitamura T.
- Journal Title
  
  Leukemia 21
  
  Pages: 2246-2257
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD2007
- Author(s)
  Lu, Y. Kitaura, J. Oki, T. Komeno, Y. Ozaki, K. Kiyono, M. Kumagai, H. Nakajima, H. Nosaka, T. Aburatani, H. Kitamura, T
- Journal Title
  
  Leukemia 21
  
  Pages: 2246-2257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD2007
- Author(s)
  Lu Y, Kitaura J, Oki T, Komeno Y, Ozaki K, Kiyono M, Kumagai H, Nakajima H, Nosaka T, Aburatani H, Kitamura T.
- Journal Title
  
  Leukemia 21
  
  Pages: 2246-2257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] MLL関連白血病の分子病態2006
- Author(s)
  小埜良一, 野阪哲哉
- Journal Title
  
  血液・腫瘍科 52(6)
  
  Pages: 615-624
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Rac 1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors.2006
- Author(s)
  Kawashima T, Bao YC, Moon Y, Tonozuka Y, Minoshima Y, Hatori T, Kiyono M, Nosaka T, Nakajima H, Williams DA, Kitamura T.
- Journal Title
  
  Journal of Cell Biology 175
  
  Pages: 937-946
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Rae 1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors2006
- Author(s)
  Kawashima, T. Bao, YC. Moon, Y. Tonozuka, Y. Minoshima, Y. Hatori, T. Kiyono, M. Nosaka, T. Nakajima, H. Williams, DA. Kitamura, T
- Journal Title
  
  J Cell Biol 175
  
  Pages: 937-946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Rac 1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcriptionfactors.2006
- Author(s)
  Kawashima T, Bao YC, Moon Y, Tonozuka Y, Minoshima Y, Hatori T, Kiyono M, Nosaka T, Nakajima H, Williams DA, Kitamura T.
- Journal Title
  
  Journal of Cell Biology 175
  
  Pages: 937-946
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] MLL関連白血病の分子病態2006
- Author(s)
  小埜良一、野阪哲哉
- Journal Title
  
  血液・腫瘍科 52(6)
  
  Pages: 615-624
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Identification of leukemia-related gene alterations : Molecular pathogenesis of leukemia, myeloproliferative disorders (MPD), and myelodysplastic syndromes (MDS)
- Author(s)
  Kitamura, T. Oki, T. Watanabe-Okochi, N. Komeno, Y. Kato, N. Yuji, K. Ono, R. Nakajima, H. Tojo, A. Nosaka, T. Kitaura, J
- Journal Title
  
  Blood Cells, Molecules and Diseases (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Journal Article] Plzf drives MLL-fusion-mediated leukemogenesis specifically in long term hematopoietic stem cells
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Nakamura A, Ishii S, Suzuki K, Shibata-Minoshima F, Katayama N, Kitamura T, Nosaka T
- Journal Title
  
  Blood
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Bahcc1 is critical for the aberrant epigenetic program in MLL-ENL-mediated leukemogenesis.2023
- Author(s)
  Akihide Nakamura, Masahiro Masuya, Isao Tawara, Tetsuya Nosaka, Ryoichi Ono
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08411
[Presentation] Tet1 is not necessarily essential for MLL-ENL-induced myeloid leukemia.2021
- Author(s)
  Ono R, Masuya M, Shinmei M, Ishii S, Maegawa Y, Maharjan BD, Katayama N, Nosaka T.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08352
[Presentation] Eya2 is critical for an aberrant self-renewal in PLZF-RARA-induced leukemogenesis.2017
- Author(s)
  Ono R, Masuya M, Ishii S, Katayama N, Nosaka T.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09452
[Presentation] Analysis of novel molecular mechanism in PLZF-mediated leukemogenesis.2016
- Author(s)
  Ono R, Masuya M, Ishii S, Katayama N, Nosaka T.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26293247
[Presentation] MYD88, CD79B, and CD79A Gene Mutations in CD5-Positive Diffuse Large B-Cell Lymphoma2016
- Author(s)
  Toshifumi Takeuchi, Motoko Yamaguchi, Kyoko Kobayashi, Kana Miyazaki, Hiroshi Imai, Ryoichi Ono, Isao Tawara, Tetsuya Nosaka, Kyosuke Tanaka and Naoyuki Katayama
- Organizer
  The 58th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego (米国)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09452
[Presentation] PLZF関連白血病発症における新規分子機構の解析2016
- Author(s)
  小埜良一、桝屋正浩、石井聡美、片山直之、野阪哲哉
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Data Source
  KAKENHI-PROJECT-15K09452
[Presentation] MYD88, CD79B, and CD79A gene mutations in CD5-positive diffuse large B-cell lymphoma.2016
- Author(s)
  Takeuchi T, Yamaguchi M, Kobayashi K, Miyazaki K, Tawara I, Imai H, Ono R, Nosaka T, Tanaka K, Katayama N.
- Organizer
  58th ASH(American Society of Hematology) Annual Meeting and Exposition
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293247
[Presentation] Immunological diversity of mucosa-associated lymphoid tissues for the development of mucosal vaccine.2015
- Author(s)
  Nagatake T, Matsumoto N, Shimojou M, Suzuki H, Fukuyama S, Sato S, Ogami K, Tsujimura Y, Kawano M, Nosaka T, Kiyono H, Yasutomi Y, Kunisawa J.
- Organizer
  第8回次世代アジュバント研究会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-01-20
- Data Source
  KAKENHI-PROJECT-24659494
[Presentation] Immunological diversity of mucosa-associated lymphoid tissues for the development of mucosal vaccine.2015
- Author(s)
  Nagatake T, Matsumoto N, Shimojou M, Suzuki H, Fukuyama S, Sato S, Ogami K, Tsujimura Y, Kawano M, Nosaka T, Kiyono H, Yasutomi Y, Kunisawa J.
- Organizer
  第8回次世代アジュバント研究会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-01-20
- Data Source
  KAKENHI-PROJECT-26293247
[Presentation] びまん性大細胞型B細胞リンパ腫細胞におけるSH3BP5, LMO3, SNAP25発現と臨床病態との関連2015
- Author(s)
  小林恭子, 山口素子, 宮崎香奈, 今井裕, 小埜良一, 野阪哲哉, 片山直之
- Organizer
  第74回日本癌学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K09452
[Presentation] Expression of SH3BP5, LMO3 and SNAP25 in diffuse large B-cell Lymphoma cells and association with clinical features.2015
- Author(s)
  Kobayashi K, Yamaguchi M, Miyazaki K, Imai H, Ono R, Nosaka T, Katayama N.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26293247
[Presentation] 白血病発症におけるPlzfによる異常な自己複製をもたらす新規分子機構の解析2014
- Author(s)
  小埜良一、桝屋正浩、片山直之、野阪哲哉
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24591390
[Presentation] Expression of LMO3 and SNAP25 in Diffuse Large B-Cell Lymphoma Cells and Its Relation to Clinical Features2014
- Author(s)
  Kobayashi K, Yamaguchi M, Miyazaki K, Imai H, Yokoe K, Ono R, Nosaka T, and Katayama N
- Organizer
  第56回アメリカ血液学会
- Place of Presentation
  米国カルフォルニア州サンフランシスコ
- Year and Date
  2014-12-07
- Data Source
  KAKENHI-PROJECT-24591390
[Presentation] MLL融合遺伝子による造血幹細胞の癌化にはPlzfを介した異常な自己複製機構が重要である2013
- Author(s)
  小埜良一、野阪哲哉
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち
- Data Source
  KAKENHI-PROJECT-24659494
[Presentation] An aberrant self-renewal program driven by Plzf is critical for leukemic transformation of hematopoietic stem cells by MLL fusion gene2013
- Author(s)
  小埜良一、野阪哲哉
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24591390
[Presentation] MLL fusion genes transform hematopoietic stem cells through an aberrant self-renewal program by Plzf2012
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Nakamura A, Ishii S, SuzukiK, Katayama N, Kitamura T, Nosaka T.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Ewing肉腫における新規腫瘍マーカーの探索:ADAMTS4発現の診断的意義の解析2011
- Author(s)
  美濃部こころ、松峯昭彦、小埜良一, ら
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] MLL融合遺伝子による白血病発症における自己複製能関連転写因子を介した新規分子機構の解析2011
- Author(s)
  小埜良一、桝屋正浩、中島秀明、榎本豊、宮田恵里、上迫努、伊藤守、中村彰秀、鈴木圭、片山直之、北村俊雄、野阪哲哉
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Ewing肉腫における新規腫瘍マーカーの探索: ADAMTS4発現の診断的意義の解析2011
- Author(s)
  美濃部こころ、松峯昭彦、小埜良一、飯野隆大、林泰秀、北村俊雄、内田淳正、須藤啓広、野阪哲也
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Differential role of PU.1 in leukemogenesis by Hoxa9-Meis1 or MLL-fusion oncogene2011
- Author(s)
  Fukuchi Y, Sadahira K, Kunimoto H, Sakurai M, Masuda A, Kawakita J, Ono R, et al
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Novel molecular mechanism of MLL-mediated leukemogenesis via a self-renewal transcription factor.2011
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Kamisako T, Ito M, NakamuraA, Suzuki K, Katayama N, Kitamura T, Nosaka T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Differential role of PU. 1 in leukemogenesis by Hoxa9-Meis1 or MLL-fusion oncogene2011
- Author(s)
  Fukuchi Y, Sadahira K, Kunimoto H, Sakurai M, Masuda A, Kawakita J, Ono R, Kitamura T, Nosaka T, Okamoto S, Nakajima H
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] 11q23転座型白血病における自己複製能関連転写因子を介した新規分子メカニズムの解析2011
- Author(s)
  小埜良一、桝屋正浩、中島秀明、榎本豊、宮田恵里、上迫努、伊藤守、中村彰秀、鈴木圭、片山直之、北村俊雄、野阪哲哉
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Differential role of PU.1 in leukemogenesis by HoxA9-Meis1 or MLL-fusion oncogene2011
- Author(s)
  Fukuchi Y, Sadahira K, Kunimoto H, Sakurai M, Masuda A, Kawakita J, Ono R, Kitamura T, Nosaka T, Okamaoto S, Nakajima H
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Analysis of novel molecular mechanism in transformation by MLL-ENL targeting long-term hematopoietic stem cells.2010
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Kamisako T, Ito M, Suzuki K, Katayama N, Kitamura T, Nosaka T.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Ikaros isoform 6 enhances proliferative effect by BCR-ABL1 in human CD34+ hematopoietic cells2010
- Author(s)
  Suzuki K, Ono R, Ohishi K, Kataoka I, Masuya M, Hamada, Kitamura T, Katayama N, Nosaka T
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] ifferential role of myeloid transcription factors, C/EBPa and PU. 1 in leukemogenesis by MLL-fusion oncogenes2010
- Author(s)
  Fukuchi Y, Kuroda K, Sadahira K, Ono R, Tenen DG, Kitamura T, Nosaka T, Okamaoto S, Nakajima H
- Organizer
  第52回アメリカ血液学会
- Place of Presentation
  米国フロリダ州オーランド
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Analysis of novel molecular mechanism in transformation by MLL-ENL targeting long-term hematopoietic stem cells2010
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Kamisako T, Ito M, Suzuki K, Katayama N, Kitamura T, Nosaka T
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Differential role of myeloid transcription factors, C/EBPα and PU.1 in leukemogenesis by MLL-fusion oncogenes2010
- Author(s)
  Fukuchi Y, Kuroda K, Sadahira K, Ono R, Tenen DG, Kitamura T, Nosaka T, Okamaoto S, Nakajima H.
- Organizer
  第52回アメリカ血液学会
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Differential role of C/EBPαand PU. 1 in leukemogenesis by MLL-fusion oncogenes2010
- Author(s)
  Fukuchi Y, Kuroda K, Sadahira K, Ono R, Ikeda Y, Kitamura T, Nosaka T, Okamaoto S, Nakajima H
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Ikaros isoform 6 enhances proliferative effect by BCR-ABL1 in human CD34+ hematopoietic cells2010
- Author(s)
  Suzuki K, Ono R, Ohishi K, Kataoka I, Masuya M, HamadaH, Kitamura T, Katayama N, Nosaka T
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Ikaros isoform 6 (IK6) enhances proliferative effect by BCR-ABL1 inhuman CD34+ hematopoietic cells.2010
- Author(s)
  Suzuki K, Ono R, et al.
- Organizer
  日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Differential role of C/EBPa and PU.1 in leukemogenesis by MLL-fusion oncogenes.2010
- Author(s)
  Fukuchi Y, Kuroda K, Sadahira K, Ono R, et al.
- Organizer
  日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Differential role of C/EBPα and PU.1 in leukemogenesis by MLL-fusion oncogenes2010
- Author(s)
  Fukuchi Y, Kuroda K, Sadahira K, Ono R, Ikeda Y, Kitamura T, Nosaka T, Okamaoto S, Nakajima H.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Analysis of novel molecular mechanism in transformation by MLL-ENL targeting long-term hematopoietic stem cells2010
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Kamisako T, Ito M, Suzuki K, Katayama N, Kitamura T, Nosaka T
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Analysis of novel molecular mechanism in transformation by MLL-ENL targeting long-term hematopoietic stem cells2010
- Author(s)
  Ono R, et al.
- Organizer
  日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] Differential role of myeloid transcription factors, C/EBPa and PU.1 in Leukemogenesis by MLL-fusion oncogenes2010
- Author(s)
  Fukuchi Y, Kuroda K, Sadahira K, Ono R, Tenen DG, KitamuraT, Nosaka T, Okamaoto S, Nakajima H
- Organizer
  第52回アメリカ血液学会
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Malignant transformation by MLL-ENL fusion gene arises selectively from long-term hematopoietic stem cells2009
- Author(s)
  Ono R, Masuya M, Miyata E, Nakajima H, Kamisako T, Ito M, Suzuki K, Katayama N, Kitamura T, Nosaka T
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] MLL-ENL融合遺伝子による形質転換は造血幹細胞のみを標的として生じる2009
- Author(s)
  小埜良一, ら
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] MLL-ENL融合遺伝子は造血幹細胞のみを標的として形質転換を生じる2009
- Author(s)
  小埜良一,桝屋正浩,宮田恵里,中島秀明,上迫努,伊藤守,鈴木圭,片山直之,北村俊雄,野阪哲哉
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] MLL-ENL融合遺伝子は造血幹細胞のみを標的として形質転換を生じる2009
- Author(s)
  小埜良一, ら
- Organizer
  日本血液学会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790911
[Presentation] AML1点変異はマウスBMTモデルにおいてMDS/AMLを発症させる2007
- Author(s)
  渡辺-大河内直子、北浦次郎、小埜良一、原田浩徳、原田結花、中島秀明、野阪哲哉、稲葉俊哉、北村俊雄
- Organizer
  第5回幹細胞シンポジウム
- Place of Presentation
  淡路島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] Hoxa9とRas-MAPキナーゼ系の協調作用がMLL融合蛋白による急性白血病の発症に重要である2007
- Author(s)
  小埜良一、熊谷英敏、中島秀明、殿塚行雄、菱谷愛、滝智彦、林泰秀、北村俊雄、野阪哲哉
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] RasGRP4と変異型AML1はマウスBMTモデルにおいて協調的に働き、T細胞性白血病を誘発する2007
- Author(s)
  渡辺(大河内)直子、沖俊彦、小埜良一、原田浩徳、湯地晃一郎、東條有伸、中島秀明、野阪哲哉、稲葉俊哉、北浦次郎、北村俊雄
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] MLL融合蛋白による多段階発癌におけるRaf-MAPキナーゼ系活性化の重要性2007
- Author(s)
  小埜良一、北村俊雄、野阪哲哉(演者)
- Organizer
  日本プロテインホスファターゼ研究会第3回国内集会
- Place of Presentation
  津
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] 活性誘導型C/EBPαおよびC/EBPεによるMLLキメラ遺伝子を有する骨髄単球性白血病細胞の単球系分化2007
- Author(s)
  松下弘道、中島秀明、中村嘉彦、塚本秀雄、田中由美子、浅井さとみ、小埜良一、野阪哲哉、安藤潔、宮地勇人
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] MLL融合蛋白はRas-MAPキナーゼ系の活性化と相乗的に協調して急性白血病を発症する2007
- Author(s)
  小埜良一、熊谷英敏、中島秀明、殿塚行雄、菱谷愛、滝智彦、林泰秀、北村俊雄、野阪哲哉
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] A BMT model mouse for myelodysplastic syndromes(MDS)and MDS/overt leukemia2006
- Author(s)
  Watanabe-Okochi N, Kitaura J, Harada H, Ono R, Inaba T, Nakajima H, Nosaka T, Kitamura T
- Organizer
  35th Annual Meeting of the International Society For Experimental Hematology
- Place of Presentation
  Minneapolis
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] MLL融合蛋白による多段階発癌にはMAPキナーゼ系の活性化が重要である2006
- Author(s)
  小埜良一、熊谷英敏、中島秀明、殿塚行雄、菱谷愛、滝智彦、林泰秀、北村俊雄、野阪哲哉
- Organizer
  第68回日本血液学会総会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] MAP kinase activation is essential for the development of acute leukemia by MLL fusion protein and FLT3 tyrosine kinase mutation2006
- Author(s)
  Ono R, Kumagai H, Nakajima H, Tonozuka Y, Hishiya A, Taki T, Hayashi Y, Kitamura T, Nosaka T
- Organizer
  48th Annual Meeting of the American Society of Hematology
- Place of Presentation
  Orlando
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] A BMT model mouse for myelodysplastic syndromes (MDS) and MDS/overt leukemia2006
- Author(s)
  Watanabe-Okochi, N. Kitaura, J. Harada, H. Ono, R. Inaba, T. Nakajima, H. Nosaka, T. Kitamura, T
- Organizer
  35th Annual Meeting of the International Society For Experimental Hematology
- Place of Presentation
  Minneapolis
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] A BMT model mice for myelodysplastic syndromes(MDS)and transformation to AML2006
- Author(s)
  Watanabe-Okochi N, Kitaura J, Harada H, Ono R, Nakajima H, Nosaka T, Inaba T, Kitamura T
- Organizer
  48th Annual Meeting of the American Society of Hematology
- Place of Presentation
  Orlando
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] AML1点変異はマウスBMTモデルにおいてMDS/AMLを発症させる2006
- Author(s)
  渡辺直子、北浦次郎、原田浩徳、小埜良一、米野由希子、佐藤均、稲葉俊哉、中島秀明、野阪哲哉、北村俊雄
- Organizer
  第68回日本血液学会総会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] A BMT model mice for myelodysplastic syndromes (MDS) and transformation to AML2006
- Author(s)
  Watanabe-Okochi, N. Kitaura, J. Harada, H. Ono, R. Nakajima, H. Nosaka, T. Inaba, T. Kitamura, T
- Organizer
  48th Annual Meeting of the American Society of Hematology
- Place of Presentation
  Orlando
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] MLL融合蛋白による多段階発癌モデルマウス:MAPキナーゼの重要性2006
- Author(s)
  小埜良一、熊谷英敏、中島秀明、殿塚行雄、菱谷愛、滝智彦、林泰秀、北村俊雄、野阪哲哉
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390278
[Presentation] Novel molecular mechanism of MLL-mediated leukemogenesis via a self-renewal transcription factor.
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Kamisako T, Ito M, Nakamura A, Suzuki K, Katayama N, Kitamura T, Nosaka T.
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] MLL fusion genes transform hematopoietic stem cells through an aberrant self-renewal program by Plzf.
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Nakamura A, Ishii S, Suzuki K, Katayama N, Kitamura T, Nosaka T.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659494
[Presentation] Analysis of novel molecular mechanisms leading to an aberrant self-renewal by Plzf in leukemogenesis.
- Author(s)
  Ono R, Masuya M, Katayama N, Nosaka T.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26293247
[Presentation] Ewing肉腫における新規腫瘍マーカーの探索：ADAMTS4発現の診断的意義の解析
- Author(s)
  美濃部こころ、松峯昭彦、小埜良一、飯野隆大、林泰秀、北村俊雄、内田淳正、須藤啓広、野阪哲哉
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Differential role of PU.1 in leukemogenesis by HoxA9-Meis1 or MLL-fusion oncogene.
- Author(s)
  Fukuchi Y, Sadahira K, Kunimoto H, Sakurai M, Masuda A, Kawakita J, Ono R, Kitamura T, Nosaka T, Okamaoto S, Nakajima H.
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Expression of LMO3 and SNAP25 in diffuse large B-cell lymphoma cells and its relation to clinical features.
- Author(s)
  Kobayashi K, Yamaguch M, Miyazaki K, Imai H, Yokoe K, Ono R, Nosaka T, Katayama N.
- Organizer
  56th American Society of Hematology Annual Meeting and Exposition.
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24659494
[Presentation] MLL fusion genes transform hematopoietic stem cells through an aberrant self-renewal program by Plzf.
- Author(s)
  Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Nakamura A, Ishii S, SuzukiK, Katayama N, Kitamura T, Nosaka T.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22390206
[Presentation] Expression of LMO3 and SNAP25 in diffuse large B-cell lymphoma cells and its relation to clinical features.
- Author(s)
  Kobayashi K, Yamaguch M, Miyazaki K, Imai H, Yokoe K, Ono R, Nosaka T, Katayama N.
- Organizer
  56th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26293247
[Presentation] MLL fusion genes transform hematopoietic stem cells through an aberrant self-renewal program by Plzf
- Author(s)
  小埜良一、桝屋正浩、中島秀明、榎本豊、宮田恵里、上迫努、伊藤守、鈴木圭、片山直之、北村俊雄、野阪哲哉
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591390
[Presentation] Analysis of novel molecular mechanisms leading to an aberrant self-renewal by Plzf in leukemogenesis.
- Author(s)
  Ono R, Masuya M, Katayama N, Nosaka T.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24659494

1. NOSAKA Tetsuya (30218309)

# of Collaborated Projects: 6 results

# of Collaborated Products: 76 results
2. KITAMURA Toshio (20282527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 40 results

Ono Ryoichi 小埜 良一

ONO Ryoichi 小埜 良一

Research Projects

Research Products

Co-Researchers

染色体11q23転座型難治性白血病における新たなエピゲノム関連分子機構の解明Principal Investigator

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Integrated analysis of the molecular basis of leukemia stem cells using a mouse model inducibly developing leukemiaPrincipal Investigator

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Integrative understanding of the functional role of DNA demethylation-associated molecule in the process of leukemic initiationPrincipal Investigator

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Novel molecular mechanism of maintenance of stemness through a DNA methylation regulator in normal and malignant hematopoiesisPrincipal Investigator

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Molecular mechanism of stem cell leukemogenesis and regulation of hematopoietic cell growth

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Analysis of molecular mechanism in leukemogenesis through an epigenome regulatorPrincipal Investigator

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Model for generation of leukemic stem cells: spatio-temporal properties in pathogenesis

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Molecular mechanism of MLL-related leukemogenesis in a mouse modelfor generation of cancer stem cells

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Novel therapeutic strategy on analysis of molecular mechanism through micro RNA in refractory leukemiaPrincipal Investigator

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11q23転座型白血病の発症機構における白血病幹細胞の分子基盤の解析Principal Investigator

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Analysis on the molecular mechanisms for the self renewal of the leukemic stem cells and for the leukemcgenesis

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[Journal Article] Bahcc1 is critical for the aberrant epigenetic program in a mouse model of MLL-ENL-mediated leukemia.2024

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Data Source

[Journal Article] Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis.2022

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DOI

Ono Ryoichi 小埜良一

ONO Ryoichi 小埜良一