Kitamura Yoshihisa 北村佳久

… Alternative Names

KITAMURA Yoshihisa 北村佳久

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Researcher Number	40423339
Other IDs	https://orcid.org/0000-0002-3652-3722
Affiliation (Current)	2025: 就実大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 就実大学, 薬学部, 教授 2020 – 2023: 就実大学, 薬学部, 教授 2012 – 2019: 岡山大学, 大学病院, 准教授 2015: 岡山大学, 医歯(薬)学総合研究科, 准教授 2015: 岡山大学, 病院, 准教授 … More 2014: 岡山大学, 大学院医歯薬学総合研究科, 准教授 2007 – 2011: Okayama University, 大学院・医歯薬学総合研究科, 准教授 2009: Okayama University, 大学院・医歯学総合研究科, 准教授 2006: 岡山大学, 大学院・医歯薬学総合研究科, 助教授 2006: Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Associate Professor, 大学院医歯薬学総合研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / Rehabilitation science/Welfare engineering / Biological pharmacy
Keywords	Principal Investigator 脳由来神経栄養因子 / 神経新生 / 精神機能 / 治療抵抗性うつ病 / 不安 / 化学療法 / シクロホスファミド / ドキソルビシン / アストロサイト / セロトニン1A受容体 … More / 電気けいれん療法 / 行動薬理学 / 脳内透析法 / セロトニン / ドパミン / モノアミン / 視床下部-下垂体-副腎皮質系 / 抗うつ薬 / GABA / 炎症 / NKCC1 / KCC2 / GABA合成酵素 / GABAA受容体 / 脳内炎症 / ミクログリア / 亜鉛 / LPS / ストレス脆弱性 / 5-HT1A受容体 / 5-HT2A受容体 / セロトニン2A受容体 / キヌレニン経路 / セロトニン神経系 / セロトニン1A受容体作用薬 / キヌレニン / AC療法 / 抗がん剤 / ラット / 認知機能 / 不安症状 / 海馬歯状回 / CREB / 電気けいれん / 8-OH-DPAT / ドパミントランスポーター / 視床下部-下垂体-腎皮質系 / 抗うっ薬 / 免疫組織化学的研究 / 海馬 / 細胞新生 / 電気けいれん刺激 / リチウム / 神経細胞新生 / 側坐核 / 薬物治療学 … More Except Principal Investigator 個別化医療 / 投与設計 / 中枢神経系 / PK/PD / 腎不全 / mRNA / CYP3A / CYP2C / ビッグデータ / 抑うつ / 副作用 / 抗がん剤 / Vigibase / JADER / 中枢抑制作用 / PKPD / 中枢抑制 / 神経栄養因子受容体 / KCC2 / TrkB / 抗不安薬 / GABA / 個別化投与 / Individual therapy / Real-time PCR / gene polymorphism / Carbamazepin / Drug metabolism / PCR / フェニトイン / 個別化治療 / Real-time PCR法 / 遺伝子情報 / カルバマゼピン / 薬物代謝酵素 / 活性型ビタミンD3 / 抗うつ活性 / 活性型ビタミンＤ３ / オープンフィールド試験 / 強制水泳試験 / ビタミンD / LC-MSMS / CYP2D6 / 遺伝子多型 / 光学異性体 / トラマドール / 向精神薬 / 薬物動態 / 肝代謝 / 炎症 / 薬物速度論 / 鎮静薬 / 睡眠薬 / 代謝 / Substance P含有神経 / NO含有神経 / Angiiotensin II受容体 / CGRP含有神経 / 交感神経節 / 脊髄後根節 / Angiotensin II type 2受容体 / Angiotensin II type 1受容体 / CGRP神経 / 血管周囲神経再分布 / ラット / 上頸交感神経節 / 脊髄後根神経節 / 神経成長因子 / 腸間膜動脈 / カルシトニン遺伝子関連ペプチド(CGRP)含有神経 / 交感神経 / 血管周囲神経 Less

肺炎症による精神機能変化の病態解明および可溶型RAGEの有用性研究Principal Investigator
- Principal Investigator
  
  北村佳久
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
医療ビッグデータと疾患モデルを用いた抗がん剤誘発抑うつ障害の予防・治療薬の開発
- Principal Investigator
  
  江角悟
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kobe Gakuin University
Involvement of astrocytes on mental function due to inflammation-induced GABAergic nerve systemPrincipal Investigator
- Principal Investigator
  
  北村佳久
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
The elucidation of the predictive of psychological changes by chemotherapy mediated the serotonin-kynurenine pathwayPrincipal Investigator
- Principal Investigator
  
  KITAMURA YOSHIHISA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
  Okayama University
Dosage individualization of antianxiety and sedative medication based on modified synaptic function of cerebral GABAergic neurons with peripheral organs failure
- Principal Investigator
  
  Aiba Tetsuya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Okayama University
Mechanism underlying potentiated pharmacological effects of sedatives with renal failure
- Principal Investigator
  
  AIBA TETSUYA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University
The elucidation of the predictive factor of psychological changes by chemotherapyPrincipal Investigator
- Principal Investigator
  
  KITAMURA YOSHIHISA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Vitamin D which is a therapeutic drug of osteoporosis may have antidepressant activity by single administration.
- Principal Investigator
  
  Kawaura Akihiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kibi International University
Effect of the CYP2D6*10 polymorphism on the pharmacokinetics and Pharmacodynamics of tramadol in cancer patients
- Principal Investigator
  
  Suno Manabu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University
Dose optimization of the central nervous system acting compound considering its altered pharmacokinetics and pharmacodynamics in patients with acute renal failure
- Principal Investigator
  
  AIBA TETSUYA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University
The elucidation of depression and treatment-resistant depression for interaction of neuron and astrocyte functionPrincipal Investigator
- Principal Investigator
  
  KITAMURA YOSHIHISA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Reinnervation and redistribution of perivascular nerves
- Principal Investigator
  
  KAWASAKI Hiiromu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Mechanisms of treatment-resistant depression on the basic study of hippocampal neurogenesis in ACTH-treated ratsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Yoshihisa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Development of animal models of treatment-resistant depression of ratsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Yoshihisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Individual therapy due to CYP genetic polymorphisms in patient with epilepsy
- Principal Investigator
  
  GOMITA Yutaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Okayama University

[Book] 視床下部-下垂体-副腎皮質系過活動モデルを用いた治療抵抗性うつ病モデルの作製および創薬への応用実験薬理学実践行動薬理学編集日本薬理学会2010
- Author(s)
  北村佳久
- Total Pages
  9
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-21590593
[Book] 視床下部-下垂体-副腎皮質系過活動モデルを用いた治療抵抗性うつ病モデルの作製および創薬への応用,実験薬理学,実践行動薬理学2010
- Author(s)
  北村佳久、浅沼幹人、宮崎育子、四宮一昭、五味田裕
- Publisher
  日本薬理学会金芳堂
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Anxiolytic-like effects of hochuekkito in lipopolysaccharide-treated mice involve interleukin-6 inhibition2022
- Author(s)
  Ushio S, Wada Y, Nakamura M, Matsumoto D, Hoshika K, Shiromizu S, Iwata N, Esumi S, Kajizono M, Kitamura Y, Sendo T.
- Journal Title
  
  Front Pharmacol
  
  Volume: 13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06714
[Journal Article] Influence of 5-HT2A receptor function on anxiety-like behavior induced by combination treatment with doxorubicin and cyclophosphamide in rats2021
- Author(s)
  Tabuchi H, Kitamura Y, Ushio S, Kan S, Wada Y, Sumiyoshi Y, Izushi Y, Miyazaki I, Asanuma M, Sendo T.
- Journal Title
  
  Psychopharmacology
  
  Volume: 238 Issue: 12 Pages: 3607-3614
- DOI
  10.1007/s00213-021-05979-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07192, KAKENHI-PROJECT-19K07993, KAKENHI-PROJECT-21K07415
[Journal Article] N-Acetylcysteine Attenuates the Anxiety-Like Behavior and Spatial Cognition Impairment Induced by Doxorubicin and Cyclophosphamide Combination Treatment in Rats2020
- Author(s)
  Kitamura Yoshihisa、Ushio Soichiro、Sumiyoshi Yusuke、Wada Yudai、Miyazaki Ikuko、Asanuma Masato、Sendo Toshiaki
- Journal Title
  
  Pharmacology
  
  Volume: in press Issue: 5-6 Pages: 1-8
- DOI
  10.1159/000512117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07993, KAKENHI-PROJECT-19K07192
[Journal Article] Influence of nicotine on doxorubicin and cyclophosphamide combination treatment-induced spatial cognitive impairment and anxiety-like behavior in rats.2017
- Author(s)
  Kitamura Y., Kanemoto E., Sugimoto M., Machida A., Nakamura Y., Naito N., Kanzaki H., Miyazaki I., Asanuma M., Sendo T.
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology
  
  Volume: 390 Issue: 4 Pages: 369-378
- DOI
  10.1007/s00210-016-1338-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08589, KAKENHI-PROJECT-16K09673
[Journal Article] Effects of imipramine and lithium on the expression of hippocampal Wnt 3a and cyclin D1 in ACTH-treated rats2014
- Author(s)
  Kitamura Y, Hayashi H, Onoue Y, Kuwatsuka K, Miyake A, Miyazaki I, Asanuma M, Sendo T.
- Journal Title
  
  Journal of Behavioral and Brain Sciences
  
  Volume: 4 Issue: 11 Pages: 483-490
- DOI
  10.4236/jbbs.2014.411048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590657
[Journal Article] Effects of Bupropion and Pramipexole on Cell Proliferation in the Hippocampus of Adrenocorticotropic Hormone-Treated Rats2014
- Author(s)
  Onoue, Y., Kuwatsuka, K., Miyazaki, I., Asanuma, M., Kitamura, Y. and Sendo, T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 2 Pages: 327-330
- DOI
  10.1248/bpb.b13-00749
- NAID
  130003390932
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24111533, KAKENHI-PROJECT-24590657, KAKENHI-PROJECT-24659431, KAKENHI-PROJECT-25461279
[Journal Article] Effects of (+)-8-OH-DPAT on the duration of immobility during the forced swim test and hippocampal cell proliferation in ACTH-treated rats2014
- Author(s)
  Miyake A., Kitamura Y., Miyazaki I., Asanuma M., Sendo T.
- Journal Title
  
  Pharmacol. Biochem. Behav.
  
  Volume: 122 Pages: 240-245
- DOI
  10.1016/j.pbb.2014.04.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590657, KAKENHI-PROJECT-24659431, KAKENHI-PROJECT-25461279
[Journal Article] The Mechanisms of Electroconvulsive Stimuli in BrdU-Positive Cells of the Dentate Gyrus in ACTH-Treated Rats2013
- Author(s)
  Kuwatsuka, K., Hayashi, H., Onoue, Y., Miyazaki, I., Koyama, T., Asanuma, M., Kitamura, Y. and Sendo, T.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 122 Issue: 1 Pages: 34-41
- DOI
  10.1254/jphs.13015FP
- NAID
  10031177878
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111533, KAKENHI-PROJECT-24590657, KAKENHI-PROJECT-24659431, KAKENHI-PROJECT-25461279
[Journal Article] ACTH反復投与ラットにおける海馬細胞新生の減少及びそのメカニズムに関する検討2012
- Author(s)
  林宏美、土居真穂、尾上由華、鍬塚圭子、三宅彩香、小山敏広、四宮一昭、宮崎育子、浅沼幹人、北村佳久
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132 Pages: 173-178
- NAID
  130001872004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Chronic treatment with imipramine and lithium increases cell proliferation in the hippocampus in adrenocorticotropic hormone-treated rats2011
- Author(s)
  Y. Kitamura, M. Doi, K. Kuwatsuka, Y. Onoue, I. Miyazaki, K. Shinomiya, T. Koyama, T. Sendo, H. Kawasaki, M. Asanuma, Y. Gomita
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34 Pages: 77-81
- NAID
  130000402266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Paracrine control of mesenteric perivascular axo-axonal interaction2011
- Author(s)
  Hiromu Kawasaki, Shingo Takatori, Yoshito Zamami, Toshihiro Koyama, Mitsunobu Goda, Kazuhiro Hirai, Panot Tangsucharit, Xin Jin, Narumi Hobara and Yoshihisa Kitamura
- Journal Title
  
  Acta Physiologica
  
  Volume: 203 Pages: 3-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590095
[Journal Article] Effects of bupropion on the forced swim test and release of dopamine in the nucleus accumbens in ACTH-treated rats2010
- Author(s)
  Y. Kitamura, T Yagi, K. Kitagawa, K. Shinomiya, H. Kawasaki, M. Asanuma, Y. Gomita
- Journal Title
  
  Naunyn-Schmiedeberg Archives of Pharmacology
  
  Volume: 382 Pages: 151-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Effects of bupropion on the forced swim test and release of dopamine in the nucleus accumbens in ACTH-treated rats.2010
- Author(s)
  Y.Kitamura
- Journal Title
  
  Naunyn-Schmiedeberg Archives of Pharmacology
  
  Volume: 382 Pages: 151-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Effects of imipramine and lithium on the suppression of cell proliferation in the dentate gyrus of the hippocampus in ACTH-treated rats2010
- Author(s)
  M. Doi, I. Miyazaki, T. Nagamachi, K. Shinomiya, H. Matsunaga, T. Sendo, H. Kawasaki, M. Asanuma, Y. Gomita, Y. Kitamura
- Journal Title
  
  Acta. Med. Okayama
  
  Volume: 64 Pages: 219-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Effects of pramipexole on the duration of immobility during the forced swim testin normal and ACTH-treated rats2009
- Author(s)
  K. Kitagawa, Y. Kitamura, T. Miyazaki, J. Miyaoka, H. Kawasaki, M. Asanuma, T. Sendo, Y. Gomita
- Journal Title
  
  Naunyn-Schmiedeberg Archives of Pharmacology (in press)
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats2009
- Author(s)
  K. Kitagawa, Y. Kitamura, T. Miyazaki, J. Miyaoka, H. Kawasaki, M. Asanuma, T. Sendo, Y. Gomita
- Journal Title
  
  Naunyn-Schmiedeberg Archives of Pharmacology
  
  Volume: 380 Pages: 59-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590593
[Journal Article] Motivational effect of nomifensine in the intracranial self-stimulation behavior using a runway method2008
- Author(s)
  H. Sagara, Y. Kitamura, T. Sendo, H. Araki, Y. Gomita
- Journal Title
  
  Bio. Pharm. Bull. 31
  
  Pages: 1036-1040
- NAID
  110006663977
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] 視床下部-下垂体-副腎皮質系過活動モデルを用いた治療抵抗性うつ病モデルの作製および薬効評価2008
- Author(s)
  北村佳久、四宮一昭、五味田裕
- Journal Title
  
  日本薬理学雑誌 132
  
  Pages: 329-333
- NAID
  10024384321
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by the chronic imipramine treatment : possible involvement of enhanced 5-HT_<2A> receptor expression in the frontal cortex2008
- Author(s)
  Y. Kitamura, K. Shibata, K. Akiyama, S. Kimoto, Y. Fujitani, K. Kitagawa, H. Kanzaki, M. Ouchida, K. Shimizu, H. Kawasaki, T. Sendo, Y. Gomita
- Journal Title
  
  J. Pharmacol Sci 106
  
  Pages: 100-106
- NAID
  10024317658
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Motivational effects of nicotine as measured in the runway method using priming stimulation of intracranial self-stimulation behavior2008
- Author(s)
  H. Sagara, Y. Kitamura, S. Esumi, T. Sendo, H. Araki, Y. Gomita
- Journal Title
  
  Acta Med. Okayama 62
  
  Pages: 227-233
- NAID
  120002305604
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Effects of imipramine and bupropion on the duration of immobility of ACTH-treated rats in the forced swim test : involvement of the expression of 5-HT_<2A> receptor mRNA2008
- Author(s)
  Y. Kitamura, Y. Fujitani, K. Kitagawa, T. Miyazaki, H. Sagara, H. Kawasaki, K. Snibata, T. Sendo, Y. Gomita
- Journal Title
  
  Biol. Pharm. Bull 31
  
  Pages: 246-249
- NAID
  110006570563
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Effect of diazepam to the runway method using priming stimulation of intracranial self stimulation behavior2008
- Author(s)
  H. Sagara, Y. Kitamura, T. Sendo, H. Araki, Y. Gomita
- Journal Title
  
  J. Pharmacol Sci. 107
  
  Pages: 355-360
- NAID
  10024321623
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] モデル動物から推察する治療抵抗性うつ病の病態および今後の治療薬2008
- Author(s)
  北村佳久、五味田裕
- Journal Title
  
  日本神経精神薬理学会雑誌 28
  
  Pages: 93-100
- NAID
  10023965506
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression : involvement of 5-HT2A receptors?2008
- Author(s)
  Y. Kitamura
- Journal Title
  
  Pharmacol. Biochem. Behav 89
  
  Pages: 235-240
- NAID
  120002306943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Motivational effects of methamphetamine as measured by the runway method using priming stimulation of intracranial self-stimulation behavior2008
- Author(s)
  H. Sagara, Y. Kitamura, T. Sendo, H. Araki, Y. Gomita
- Journal Title
  
  Biol. Pharm. Bull 31
  
  Pages: 541-545
- NAID
  110006680481
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] 視床下部-下垂体-副腎皮質系過活動モデルを用いた治療抵抗性うつ病モデルの作製および薬効評価2008
- Author(s)
  北村佳久
- Journal Title
  
  日本薬理学雑誌 132
  
  Pages: 329-333
- NAID
  10024384321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Selegilin exerts antidepressant-like effects during the forced swim test in ACTH-treated rats2008
- Author(s)
  Y. Kitamura, K. Kitagawa, S. Kimoto, H. Sagara, K. Shibata, H. Kawasaki, T. Sendo, Y. Gomita
- Journal Title
  
  J. Pharmacol Sci 106
  
  Pages: 639-644
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] モデル動物から推察する治療抵抗性うつ病の病態および今後の治療薬2008
- Author(s)
  北村佳久
- Journal Title
  
  日本神経精神薬理学会雑誌 28
  
  Pages: 93-100
- NAID
  10023965506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression : involvement of 5-HT2A receptors?2008
- Author(s)
  Y. Kitamura, K. Akiyama, K. Kitagawa, K. Shibata, H. Kawasaki, K. Suemaru, H. Araki, T. Sendo, Y. Gomita
- Journal Title
  
  Pharmacol. Biochem. Behav 89
  
  Pages: 235-240
- NAID
  120002306943
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Nicotinic acetylcholine alpha4beta2 receptor regulates the motivational effect of intracranial self stimulation behavior in the runway method2008
- Author(s)
  H. Sagara, Y. Kitamura, T. Yae, K. Shibata, K. Suemaru, T. Sendo. H. Araki, Y. Gomita
- Journal Title
  
  J. Pharmacol. Sci. 108
  
  Pages: 455-61
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by the chronic imipramine treatment: possible involvement of enhanced 5-HT_<2A> receptor expression in the frontal cortex.2008
- Author(s)
  Y. Kitamura
- Journal Title
  
  J. Pharmacol Sci. 106
  
  Pages: 100-106
- NAID
  10024317658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Selegilin exerts antidepressant-like effects during the forced swim test in ACTH-treated rats.2008
- Author(s)
  Y. Kitamura
- Journal Title
  
  J. Pharmacol Sci. 106
  
  Pages: 639-644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Effects of imipramine and bupropion on the duration of immobility of ACTH-treated rats in the forced swim test: involvement of the expression of 5-HT_<2A> receptor mRNA.2008
- Author(s)
  Y. Kitamura
- Journal Title
  
  Biol. Pharm. Bull. 31
  
  Pages: 246-249
- NAID
  110006570563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Strategy to develop a new drug for treatment-resistant depression -Role of electroconvulsive stimuli and BDNF-2007
- Author(s)
  B. Li, K. Suemaru, Y. Kitamura, R. Cui, Y. Gomita, H Araki
- Journal Title
  
  Yakugaku Zasshi 127
  
  Pages: 735-742
- NAID
  110006242880
- Data Source
  KAKENHI-PROJECT-19590535
[Journal Article] Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats.2007
- Author(s)
  Y. Kitamura
- Journal Title
  
  Eur. J. Pharmacol. 566
  
  Pages: 113-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] LPS投与による不安様症状およびミクログリア活性化に対する亜鉛の効果2023
- Author(s)
  田中翔哉、出石恭久、吾郷拓磨、植田哲平、田坂祐一、宮崎育子、浅沼幹人、北村佳久
- Organizer
  第７回日本精神薬学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K06714
[Presentation] LPS経気道内投与による不安様症状およびミクログリア活性化に対する作用2023
- Author(s)
  田中翔哉、出石恭久、吾郷拓磨、植田哲平、田坂祐一、徳永智典、宮崎育子、浅沼幹人、北村佳久
- Organizer
  第62回　日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-22K06714
[Presentation] Involvement of 5-HT1A receptor in the anxiety-like behavior induced by doxorubicin and cyclophosphamide combination treatment in rats.2020
- Author(s)
  Yoshihisa Kitamura, Soichiro Ushio, Yudai Wada, Toshiaki Sendo
- Organizer
  2020 Forbidden City International Pharmacist Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07192
[Presentation] Effects of serotonin1A receptor agonist on doxorubicin and cyclophosphamide-induced anxiety-like behavior in rats2019
- Author(s)
  Yoshihisa Kitamura, Yuka Nakamura, Yusuke Sumiyoshi, Nanami Naito, Yudai Wada, Ikuko Miyazaki, Masato Asanuma, Toshiaki Sendo
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07192
[Presentation] Influence of nicotine on doxorubicin and cyclophosphamide-induced spatial cognitive impairment and anxiety-like behavior in rats2017
- Author(s)
  Yoshihisa Kitamura, Misaki Sugimoto, Erika Kanemoto, Ayumi Machida, Yuka Nakamura, Nanami Naito, Ikuko Miyazaki, Masato Asanuma, Toshiaki Sendo
- Organizer
  Neuroscience2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08589
[Presentation] 抗がん剤投与による精神機能変化の発症機序とミルタザピンの改善効果2017
- Author(s)
  中村優花, 住吉佑介, 内藤七海, 牛尾聡一郎, 宮崎育子, 浅沼幹人, 北村佳久, 千堂年昭
- Organizer
  第28回霧島神経薬理フォーラム
- Data Source
  KAKENHI-PROJECT-15K08589
[Presentation] Effects of mirtazapine on doxorubicin and cyclophosphamide-induced spatial cognitive impairment and anxiety-like behavior in rats2017
- Author(s)
  Yuka Nakamura, Yoshihisa Kitamura, Nanami Naito, Yusuke. Sumiyoshi, Ikuko Miyazaki, Masato Asanuma, Toshiaki Sendo
- Organizer
  Neuroscience2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08589
[Presentation] Doxorubicin and cyclophosphamide treatment causes anxiety-like behavior and spatial cognition impairment in rats2016
- Author(s)
  Yoshihisa Kitamura, Misaki Sugimoto, Erika Kanemoto, Ayumi Machida, Yuka Nakamura, Hirotaka Kanzaki, Toshiaki Sendo
- Organizer
  第27回日本医療薬学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-15K08589
[Presentation] Effects of nicotine on doxorubicin and cyclophosphamide-induced spatial cognition and anxiety in rats2015
- Author(s)
  Misaki Sugimoto, Erika Kanemoto, Saori Watanabe, Ikuko Miyazaki, Masato Asanuma, Yoshihisa Kitamura, Toshiaki Sendo
- Organizer
  Neuroscience2015
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08589
[Presentation] Doxorubicin and cyclophosphamide treatment causes anxiety-like behavior and spatial cognition impairment in rats2015
- Author(s)
  Yoshihisa Kitamura, Saori　Watanabe, Saori Yoneda, Misaki Sugimoto, Erika Kanemoto, Hirotaka Kanzaki, Ayumi Machida, Ikuko Miyazaki, Masato Asanuma, Toshiaki Sendo
- Organizer
  Neuroscience2015
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08589
[Presentation] トラマドール光分解特性の解析およびトラマドール内用液剤の光安定性の評価2014
- Author(s)
  市原英則，青木和葉，石野貴大，遠藤友理子，須野学，北村佳久，千堂年昭
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460213
[Presentation] ACTH反復投与ラットにおける5-HT1A受容体アゴニストの抗うつ効果および海馬神経新生に与える影響2013
- Author(s)
  三宅彩香、北村佳久、服部紗代、小山敏広、宮崎育子、浅沼幹人、千堂年昭
- Organizer
  第86回日本薬理学会　年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590657
[Presentation] ACTH反復投与ラットにおける5-HT1A受容体アゴニストの海馬神経新生および細胞内シグナリング伝達系に関する検討2012
- Author(s)
  三宅彩香、小山敏広、宮崎育子、浅沼幹人、北村佳久
- Organizer
  第6回次世代を担う若手医療科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590657
[Presentation] ACTH反復投与ラットにおける海馬細胞新生の減少に対するimipramine、lithiumの作用に関する検討2011
- Author(s)
  林宏美、土井真穂、尾上由華、鍬塚圭子、小山敏広、四宮一昭、宮崎育子、浅沼幹人、北村佳久
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] Effects of electroconvulsive stimuli on neurogenesis in dentate gyrus of ACTH-treated rats2011
- Author(s)
  T. Koyama, H Hayashi, K. Kuwatsuka, Y. Onoue, M. Doi, I. Miyazaki, M. Asanuma, Y. Kitamura
- Organizer
  Neuroscience 2011
- Place of Presentation
  WashingtonDC(USA)
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] Effects of imipramine and lithium on the suppression of cell proliferation in the dentate gyrus of the hippocampus in ACTH-treated rats2011
- Author(s)
  K. Kuwatsuka, Y. Onoue, H. Hayashi, M. Doi, T. Koyama, I. Miyazaki, M. Asanuma, Y. Kitamura
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC(USA)
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] ACTH反復投与ラットにおける海馬細胞新生の減少およびそのメカニズムに関する検討2011
- Author(s)
  林宏美、土井真穂、尾上由華、鍬塚圭子、三宅綾香、小山敏広、四宮一昭、宮崎育子、浅沼幹人、北村佳久
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] ACTH反復投与ラットを用いたbupropionの抗うつ効果におけるドパミン神経機能の関与2010
- Author(s)
  八木貴彦、宮崎俊明、北川航平、四宮一昭、浅沼幹人、千堂年昭、北村佳久
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] Influence of the suppression of cell proliferation and neurogenesis in the ability of antidepressants in an ACTH-induced animal model of treatment-resistant2010
- Author(s)
  Y. Kitamura, M. Doi, H. Hayashi, I. Miyazaki, M. Asanuma, H. Kawasaki
- Organizer
  World Pharma 2010
- Place of Presentation
  Copenhagen
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] ACTH反復投与ラットを用いた海馬歯状回における細胞増殖およびアストログリア活性に及ぼす影響2010
- Author(s)
  土居真穂、長町智子、江川真季、宮崎育子、川崎博己、千堂年昭、浅沼幹人、北村佳久
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] Influence of the suppression of cell proliferation and neurogenesis in the ability of antidepressants in an ACTH-induced animal model of treatment-resistant.2010
- Author(s)
  Y.Kitamura
- Organizer
  WorldPharma2010
- Place of Presentation
  Copenhagen
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] ACTH反復投与ラットにおける中枢ドパミントランスポーター発現に関する検討2009
- Author(s)
  江本清香、北村佳久、宮崎育子、北川航平、長町智子、土居真穂、石丸由衣、浅沼幹人、千堂年昭
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] Priming stimulation 効果を用いたRunway 法におけるnomifensineの動機付け促進作用2009
- Author(s)
  江角悟、相良英憲、北村佳久、五味田裕、千堂年昭
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] Effects of imipramine and lithium on the supression of cell proliferation and neurogenesis of dentate gyrus of hippocampus in ACTH-treated rats2009
- Author(s)
  M. Doi, I. Miyazaki, K. Shinomiya, M. Asanuma, Y. Kitamura
- Organizer
  The 1st Meeting of Asain College of Neuropsychopharmacology
- Place of Presentation
  Kyoto
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21590593
[Presentation] Run-way 法による意欲・動機付け評価へのドパミンD2 受容体の影響2008
- Author(s)
  江角悟、相良英憲、北村佳久、五味田裕、千堂年昭
- Organizer
  第38回日本神経精神薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] ACTH投与ラットに対するドパミンD2/D3受容体アゴニストであるプラミペキソールの抗うつ様効果における脳部位の特定2008
- Author(s)
  宮崎俊明、北村佳久、宮岡純也、北川航平、松永康臣、千堂年昭、五味田裕
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] Morohine 単回投与ラットにおけるnaloxonw 誘発条件付け場所嫌悪行動に対するα7ニコチン性受容体拮抗薬の影響2008
- Author(s)
  石田茂、師橋一徳、生田祐一、北村佳久、荒木博陽、千堂年昭、五味田裕
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] Development of animal model of treatment-resistant-depression in rats - Effects of antidepressants on the duration of immobility of ACTH-treated rats in the forced swim test-2008
- Author(s)
  Y. Kitamura, K. Kitagawa, T. Miyazaki, T. Nagamachi,M. Doi, I. Miyazaki, M. Asanuma, T. Sendo, H. Kawasaki, Y. Gomita
- Organizer
  Neuroscinence 2008
- Place of Presentation
  ワシントンDC
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] Development of animal model of treatment-resistant-depression in rats -Effects of antidepressants on the duration of immobility of ACTH-treated rats in the forced swim test -2008
- Author(s)
  Y. Kitamura
- Organizer
  Neuroscinence 2008
- Place of Presentation
  ワシントンDC
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] ラット海馬神経細胞及びアストロサイトの形態学的変化に対するACTH反復投与の影響2008
- Author(s)
  長町智子、宮崎育子、江本清香、土居真穂、川崎博己、浅沼幹人、北村佳久、千堂年昭、五味田裕
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] 海馬神経細胞およびアストロサイトの形態学的変化から見た治療抵抗性うつ病の病態解明の試み2007
- Author(s)
  長町智子、北村佳久、藤谷佳可、宮崎敏明、江本清香、土居真穂、宮崎育子、浅沼幹人、川崎博己、千堂年昭、五味田裕
- Organizer
  第18回霧島神経薬理フォーラム
- Place of Presentation
  愛媛
- Year and Date
  2007-08-24
- Data Source
  KAKENHI-PROJECT-19590535
[Presentation] Involvement of the 5-HT1A receptor function in the 8-OH-DPAT treatment on neurogenesis in ACTH-treated rats
- Author(s)
  Kitamura Y., Miyake A, Hattori S., Koyama T., Miyazaki I., Asanuma M., Sendo T.
- Organizer
  Neuroscience2013
- Place of Presentation
  Washington DC（USA）
- Data Source
  KAKENHI-PROJECT-24590657

1. ASANUMA Masato (00273970)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
2. KAWASAKI Hiromu (60125151)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
3. GOMITA Yutaka (00088709)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
4. AIBA TETSUYA (00231754)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKATORI Shingo (20368707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HASHIKAWA Narumi (30511159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. KOYAMA Toshihiro (60595106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. Suno Manabu (20621189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. NAGASAKA Takeshi (30452569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kawaura Akihiko (00177643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. AKIYAMA Jyunichi (00309600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIZUTANI Kasatoshi (30108170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIMIZU Kenji (10037286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SENDO Toshiaki (30437561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 江角悟 (90939927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 座間味義人 (70550250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 牛尾聡一郎 (80939893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HINO Hayato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 宮崎育子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kitamura Yoshihisa 北村 佳久

KITAMURA Yoshihisa 北村 佳久

Research Projects

Research Products

Co-Researchers

肺炎症による精神機能変化の病態解明および可溶型RAGEの有用性研究Principal Investigator

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Involvement of astrocytes on mental function due to inflammation-induced GABAergic nerve systemPrincipal Investigator

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The elucidation of the predictive of psychological changes by chemotherapy mediated the serotonin-kynurenine pathwayPrincipal Investigator

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The elucidation of the predictive factor of psychological changes by chemotherapyPrincipal Investigator

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The elucidation of depression and treatment-resistant depression for interaction of neuron and astrocyte functionPrincipal Investigator

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Mechanisms of treatment-resistant depression on the basic study of hippocampal neurogenesis in ACTH-treated ratsPrincipal Investigator

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Development of animal models of treatment-resistant depression of ratsPrincipal Investigator

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Kitamura Yoshihisa 北村佳久

KITAMURA Yoshihisa 北村佳久

[Book] 視床下部-下垂体-副腎皮質系過活動モデルを用いた治療抵抗性うつ病モデルの作製および創薬への応用実験薬理学実践行動薬理学編集日本薬理学会2010