SHIRAISHI Naoki 白石直樹

… Alternative Names

白石直樹シライシナオキ

Less

Researcher Number	40423660
Affiliation (based on the past Project Information) *help	2012 – 2014: 熊本大学, 大学院生命科学研究部, 助教 2010 – 2011: 熊本大学, 大学院・生命科学研究部, 助教 2009: Kumamoto University, 大学院・生命科学研究部, 特任助教 2006 – 2007: 熊本大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Kidney internal medicine
Keywords	Principal Investigator プロスタシン / 生体分子 / 腎障害 / インスリン抵抗性 / 糖尿病 / 腎不全 / 酸化ストレス / 線維化 / セリンプロテアーゼ / 生理活性 … More / シグナル伝達 / PN-1 / TGFβ / 腎線維化 / 酵素 Less

プロテアーゼおよび酸化ストレスによるヴィシャスサイクルメカニズムの解明Principal Investigator
- Principal Investigator
  
  白石直樹
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
elucidation of physiological roles of prostasin and its signaling pathwayPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Naoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
プロスタシンの腎線維化に関する研究Principal Investigator
- Principal Investigator
  
  白石直樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University

All 2014 2013 2012 2011 2010 2009 2006

All Journal Article Presentation

[Journal Article] Amyloid A amyloidosis in a Japanese patient with familial Mediterranean fever associated with homozygosity for the pyrin variant M694I/M694I2014
- Author(s)
  Nakamura T, Migita K, Ando Y, Takaoka H, Suzushima H, Shiraishi N
- Journal Title
  
  Mod Rheumatol
  
  Volume: 24 Issue: 2 Pages: 349-352
- DOI
  10.3109/14397595.2013.852844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591207
[Journal Article] The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.2014
- Author(s)
  Uchimura K, Hayata M, Mizumoto T, Miyasato Y, Kakizoe Y, Morinaga J, Onoue T, Yamazoe R, Ueda M, Adachi M, Miyoshi T, Shiraishi N, Ogawa W, Fukuda K, Kondo T, Matsumura T, Araki E, Tomita K, Kitamura K.
- Journal Title
  
  Nat Commun.
  
  Volume: 11 Issue: 1 Pages: 3428-3428
- DOI
  10.1038/ncomms4428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126011, KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-24591206, KAKENHI-PROJECT-24591207, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461374
[Journal Article] The antifibrotic effect of a serine protease inhibitor in the kidney2013
- Author(s)
  Morinaga, J., Kakizoe, Y., Miyoshi, T., Onoue, T., Ueda, M., Mizumoto, T., Yamazoe, R., Uchimura, K., Hayata, M., Shiraishi, N., Adachi, M., Sakai, Y., Tomita, K., and Kitamura, K.
- Journal Title
  
  Am. J. Physiol. (Renal Physiol.)
  
  Volume: 305 Issue: 2 Pages: F173-F181
- DOI
  10.1152/ajprenal.00586.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591206, KAKENHI-PROJECT-24591207
[Journal Article] Prevalence and risk factor analysis of nephrosclerosis and ischemic nephropathy in the Japanese general population2013
- Author(s)
  Shiraishi N, Kitamura K, Kohda Y, Iseki K, Tomita K
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591207
[Journal Article] Case of anti-glomerular basement membrane antibody-induced glomerulonephritis with cytomegalovirus-induced thrombotic microangiopathy2012
- Author(s)
  Shiraishi-N, Kitamura-K, Hayata-M, Ogata-T, Adachi-M, Kajiwara-K, Ikeda-H, Miyoshi-T, Tomita-K
- Journal Title
  
  Internal medical Journal
  
  Volume: 42(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591056
[Journal Article] Case of anti-glomerular basement membrane abntibody-induced glomerul onephritis with cytomegalovirus-induced thrombotic microangiopathy2012
- Author(s)
  Shiraishi-N, et al
- Journal Title
  
  Intern Med J
  
  Volume: 42(3) Issue: 3
- DOI
  10.1111/j.1445-5994.2011.02703.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591056, KAKENHI-PROJECT-24591207
[Journal Article] A study of maintenance therapy after intravenous maxacalcitol for secondary hyperparathyroidism2011
- Author(s)
  Adachi-M, Miyoshi-T, Shiraishi-N, Shimada-H, Sakaguchi-S, Tomita-K, Kitamura-K
- Journal Title
  
  Clin Nephrol
  
  Volume: 76(4) Pages: 266-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591056
[Journal Article] 【腎不全の最近の動向と阻止対策】腎硬化症2011
- Author(s)
  白石直樹、冨田公夫
- Journal Title
  
  カレントテラピー
  
  Volume: 29(8) Pages: 677-686
- Data Source
  KAKENHI-PROJECT-21591056
[Journal Article] 腹部エコー検査2010
- Author(s)
  白石直樹, 他
- Journal Title
  
  腎と透析
  
  Volume: 68巻5号 Pages: 792-795
- Data Source
  KAKENHI-PROJECT-21591056
[Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin2010
- Author(s)
  Ko T, Kakizoe Y, Wakida N, Hayata M, Uchimura K, Shiraishi N, Miyoshi T, Adachi M, Aritomi S, Konda T, Tomita K, Kitamura K
- Journal Title
  
  J Biomed Biotechnol
  
  Pages: 793843-793843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591056
[Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats2009
- Author(s)
  Kakizoe Y, Kitamura K, Ko T, Wakida N, Maekawa A, Miyoshi T, Shiraishi N, Adachi M, Zhang Z, Masilamani S, Tomita K
- Journal Title
  
  J Hypertens
  
  Volume: 27(8) Pages: 1679-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591056
[Journal Article] Successful treatment of a patient with severe calcific uremic arteriolopathy by etidronate disodium2006
- Author(s)
  Naoki Shiraishi
- Journal Title
  
  American Journal of Kidney Disease Vol48 no1
  
  Pages: 151-154
- Data Source
  KAKENHI-PROJECT-18790570
[Presentation] CKDに対するメシル酸カモスタット（CM）とARBの腎保護効果の検討2013
- Author(s)
  植田美紀、内村幸平、成田勇樹、水本輝彦、尾上友朗、山添リカ、森永潤、早田学、白石直樹、實吉拓、安達政隆、酒井芳紀、冨田公夫、北村健一郎
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24591207
[Presentation] 維持血液透析患者における血清Angptl2値と動脈硬化の関係2013
- Author(s)
  山添リカ、森永潤、内村幸平、早田学、尾上友朗、水本輝彦、植田美紀、安達政隆、白石直樹、實吉拓、田尻宗誠、尾池雄一、冨田公夫、北村健一郎
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24591207
[Presentation] アルドステロンによる上波型Naチャネル活性化におけるセリンプロテアーゼ阻害薬の効果2011
- Author(s)
  柿添豊, 北村健一郎, 内村幸平, 早田学, 森永潤, 尾上友朗, 水本輝彦, 安達政隆, 實吉拓, 白石直樹, 酒井芳紀, 冨田公夫
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21591056
[Presentation] A synthetic serine protease inhibitor camostat mesilate attenuates renal interstitial fibrosis in rats2011
- Author(s)
  Morinaga-J, Kakizoe-Y, Miyoshi-T, Onoue-T, Mizumoto-T, Hayata-M, Uchimura-K, Shiraishi-N, Adachi-M, Sakai-Y, Tomita-K, Kitamura-K
- Organizer
  American Society of Nephrology Kidney Week 2011
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, PA
- Data Source
  KAKENHI-PROJECT-21591056
[Presentation] 片側尿管結紮モデル(UUO)ラットにおけるメシル酸カモスタットの効果2011
- Author(s)
  森永潤, 北村健一郎, 尾上友朗, 水本輝彦, 内村幸平, 早田学, 柿添豊, 安達政隆, 實吉拓, 白石直樹, 酒井芳紀, 冨田公夫
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-21591056
[Presentation] A synthetic serine protease inhibitor camostat mesilate inhibited the proteolytic activation of gENaC in the kidney of the aldosterone-infused rats2011
- Author(s)
  Uchimura-K, Kakizoe-Y, Onoue-T, Hayata-M, Morinaga-J, Mizumoto-T, Adachi-M, Miyoshi-T, Shiraishi-N, Sakai-Y, Tomita-K, Kitamura-K
- Organizer
  American Society of Nephrology Kidney Week 2011
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, PA
- Data Source
  KAKENHI-PROJECT-21591056
[Presentation] 腎硬化症、虚血性腎症の発症率と危険因子の同定に関する研究2011
- Author(s)
  白石直樹, 冨田公夫
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21591056
[Presentation] アルドステロンによる腎障害に対するメシル酸カモスタットの効果2010
- Author(s)
  柿添豊, 北村健一郎, 内村幸平, 早田学, 森永潤, 安達政隆, 白石直樹, 實吉拓, 酒井芳紀, 冨田公夫
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21591056
[Presentation] ラット腎虚血再灌流障害におけるセリンプロテアーゼの役割2010
- Author(s)
  早田学, 北村健一郎, 柿添豊, 内村幸平, 森永潤, 安達政隆, 白石直樹, 實吉拓, 冨田公夫, 酒井芳紀
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21591056

1. TOMITA Kimio (40114772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
2. 北村健一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 小川渉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIRAISHI Naoki 白石 直樹

白石 直樹 シライシ ナオキ

Research Projects

Research Products

Co-Researchers

プロテアーゼおよび酸化ストレスによるヴィシャスサイクルメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

elucidation of physiological roles of prostasin and its signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロスタシンの腎線維化に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Amyloid A amyloidosis in a Japanese patient with familial Mediterranean fever associated with homozygosity for the pyrin variant M694I/M694I2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The antifibrotic effect of a serine protease inhibitor in the kidney2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prevalence and risk factor analysis of nephrosclerosis and ischemic nephropathy in the Japanese general population2013

Author(s)

Journal Title

Data Source

[Journal Article] Case of anti-glomerular basement membrane antibody-induced glomerulonephritis with cytomegalovirus-induced thrombotic microangiopathy2012

Author(s)

Journal Title

Data Source

[Journal Article] Case of anti-glomerular basement membrane abntibody-induced glomerul onephritis with cytomegalovirus-induced thrombotic microangiopathy2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A study of maintenance therapy after intravenous maxacalcitol for secondary hyperparathyroidism2011

Author(s)

Journal Title

Data Source

[Journal Article] 【腎不全の最近の動向と阻止対策】腎硬化症2011

Author(s)

Journal Title

Data Source

[Journal Article] 腹部エコー検査2010

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin2010

Author(s)

Journal Title

Data Source

[Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats2009

Author(s)

Journal Title

Data Source

[Journal Article] Successful treatment of a patient with severe calcific uremic arteriolopathy by etidronate disodium2006

Author(s)

Journal Title

Data Source

[Presentation] CKDに対するメシル酸カモスタット（CM）とARBの腎保護効果の検討2013

Author(s)

Organizer

Place of Presentation

Data Source

SHIRAISHI Naoki 白石直樹

白石直樹シライシナオキ