Inouye Satoshi 井上敏

… Alternative Names

INOUYE Satoshi 井上敏

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Researcher Number	40426622
Other IDs	https://orcid.org/0000-0001-8732-7839
Affiliation (Current)	2025: チッソ株式会社横浜研究所, その他部局等, その他
Affiliation (based on the past Project Information) *help	2016: JNC(株), 横浜研究所, 企画研究員 2013: JNC(株), 横浜研究所, 主席研究員 2013: JNC株式会社, 横浜研究所, 主席研究員東京工業大学・バイオフロンティアセンター・特任教授 2012: JNC株式会社, 横浜研究所, 主席研究員
Review Section/Research Field	Except Principal Investigator Chemical biology / Functional basic dentistry
Keywords	Except Principal Investigator 生物発光 / 分子プローブ / 有機化学 / ケミカルバイオロジー / タンパク質分泌 / 開口分泌 / 骨形成 / 分泌 / エキソサイトーシス / 骨形成因子 … More / 骨芽細胞 / ルシフェラーゼ / 細胞接着 / 3D培養 / 遺伝子発現 / イメージング / ホウ素化合物 / 活性酸素種 / 分子イメージング / bioluminescence / cell migration / Bioluminescence imaging / coelenterazine / exocytosis / Gaussia luciferase / bioluminescence imaging / 遊走細胞 / がん細胞 / MMP-2 / 生物発光イメージング Less

Bioluminescence imaging for osteogenic protein secretion
- Principal Investigator
  
  Suzuki Takahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Development of new coelenterazine analogue for in vivo imaging of reactive oxygen species
- Principal Investigator
  
  HOSOYA Takamitsu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Tokyo Medical and Dental University
Bioluminescence imaging of MMP-2 and its related proteins secretion
- Principal Investigator
  
  SUZUKI Takahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Synthesis of new substrates for near-infrared bioluminescence imaging
- Principal Investigator
  
  YOSHIDA Suguru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Tokyo Medical and Dental University

All 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Patent

[Journal Article] Quantitative visualization of synchronized insulin secretion from 3D-cultured cells.2017
- Author(s)
  Suzuki T, Kanamori T, Inouye S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 486 Issue: 4 Pages: 886-892
- DOI
  10.1016/j.bbrc.2017.03.105
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462828, KAKENHI-PROJECT-17K11658
[Journal Article] Visualization of glucagon secretion from pancreatic α cells by bioluminescence video microscopy: identification of secretion sites in the intercellular contact regions2017
- Author(s)
  Yokawa, S., Suzuki, T., Inouye, S., Inoh, Y., Suzuki, R., Kanamori, T., Furuno, T., Hirashima, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 485 Issue: 4 Pages: 725-730
- DOI
  10.1016/j.bbrc.2017.02.114
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440083, KAKENHI-PROJECT-26460041, KAKENHI-PROJECT-26462828, KAKENHI-PROJECT-16H05082, KAKENHI-PROJECT-15K14495
[Journal Article] Protein expression of preferred human codon-optimized Gaussia luciferase genes with an artificial open-reading frame in mammalian and bacterial cells.2016
- Author(s)
  Inouye S, Suzuki T
- Journal Title
  
  Protein Expr. Purif.
  
  Volume: 128 Pages: 93-100
- DOI
  10.1016/j.pep.2016.08.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462828
[Journal Article] Codon optimization of genes for efficient protein expression in mammalian cells by selection of only preferred human codons.2015
- Author(s)
  Inouye S, Sahara-Miura Y, Sato J, Suzuki T.
- Journal Title
  
  Protein Expr Purif.
  
  Volume: 109 Pages: 47-54
- DOI
  10.1016/j.pep.2015.02.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462828
[Journal Article] Unconventional secretion of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) in mammalian cells.2014
- Author(s)
  Inouye S, Sato J-I, Sahara-Miura Y, Hosoya T, Suzuki T
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 450 Issue: 4 Pages: 1313-1319
- DOI
  10.1016/j.bbrc.2014.06.140
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462828
[Journal Article] Luminescence enhancement of the catalytic 19 kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions2014
- Author(s)
  S. Inouye, J.-i. Sato, Y. Sahara-Miura, S. Yoshida, and T. Hosoya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 445 Issue: 1 Pages: 157-162
- DOI
  10.1016/j.bbrc.2014.01.133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651257
[Journal Article] Video-rate bioluminescence imaging of protein secretion from a living cell2014
- Author(s)
  Suzuki T and Inouye S
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1098 Pages: 71-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592754
[Journal Article] ビデオレート生物発光イメージング法によるタンパク質分泌動態の可視化2014
- Author(s)
  鈴木崇弘、井上敏
- Journal Title
  
  生化学
  
  Volume: 86 (2)
- NAID
  40020096317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592754
[Journal Article] C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase.2013
- Author(s)
  S. Inouye, J.-i. Sato, Y. Sahara-Miura, S. Yoshida, H. Kurakata, and T. Hosoya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 437 Issue: 1 Pages: 23-28
- DOI
  10.1016/j.bbrc.2013.06.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651257
[Journal Article] 生物発光系によるin vivoイメージングを指向した発光基質の開発2013
- Author(s)
  細谷孝充、隅田有人、吉田優、鈴木崇弘、井上敏
- Journal Title
  
  日本分子イメージング学会機関誌
  
  Volume: 6 Pages: 3-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710266
[Journal Article] Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: Comparison of substrate specificity for C2-modified coelenterazines2013
- Author(s)
  Satoshi Inouye, Yuiko Sahara-Miura, Jun-ichi Sato, Rie Iimori, Suguru Yoshida, Takamitsu Hosoya
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 88 Issue: 1 Pages: 150-156
- DOI
  10.1016/j.pep.2012.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710266, KAKENHI-PROJECT-24651257
[Journal Article] 生物発光系によるin vivoイメージングを指向した発光基質の開発2013
- Author(s)
  細谷孝充,隅田有人,吉田優,鈴木崇弘,井上敏
- Journal Title
  
  日本分子イメージング学会機関誌
  
  Volume: 6 Pages: 3-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651257
[Journal Article] Video rate bioluminescence imaging of secretory proteins in living cells: localization, secretory frequency, and quantification2011
- Author(s)
  Suzuki T, Kondo C, Kanamori T, Inouye S
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 415 Pages: 182-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592754
[Journal Article] Cell selective targeting of a simian virus 40 virus-like particle conjugated to epidermal growth factor2011
- Author(s)
  Kitai Y, Fukuda H, Enomoto T, Asakawa Y, Suzuki T, Inouye S, Handa H
- Journal Title
  
  Journal of Biotechnology
  
  Volume: 155 Pages: 251-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592754
[Journal Article] Video-rate bioluminescence imaging of matrix metalloproteinase-2 secreted from a migrating cell.2011
- Author(s)
  Suzuki T, Kondo C, Kanamori T, Inouye S
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 9 Pages: e25243-e25243
- DOI
  10.1371/journal.pone.0025243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592754
[Journal Article] Video-rate bioluminescence imaging of matrix metalloproteinase-2 secreted from a migrating cell2011
- Author(s)
  Suzuki T, Kondo C, Kanamori T, Inouye S
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592754
[Patent] v-セレンテラジン化合物の製造方法2012
- Inventor(s)
  井上敏、佐原由依子、吉田優、細谷孝充
- Industrial Property Rights Holder
  井上敏、佐原由依子、吉田優、細谷孝充
- Filing Date
  2012-03-06
- Overseas
- Data Source
  KAKENHI-PROJECT-23710266
[Patent] v-セレンテラジン化合物の製造方法2012
- Inventor(s)
  井上敏、佐原由依子、吉田優、細谷孝充
- Industrial Property Rights Holder
  井上敏、佐原由依子、吉田優、細谷孝充
- Filing Date
  2012-03-06
- Overseas
- Data Source
  KAKENHI-PROJECT-23710266
[Patent] v-セレンテラジン化合物の製造方法2012
- Inventor(s)
  井上　敏、佐原由依子、吉田　優、細谷孝充
- Industrial Property Rights Holder
  井上　敏、佐原由依子、吉田　優、細谷孝充
- Filing Date
  2012
- Overseas
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] 膵β細胞塊における同調性インスリン分泌の可視化2016
- Author(s)
  鈴木崇弘, 井上敏
- Organizer
  第15回生命科学研究会
- Place of Presentation
  メルパルク東京（東京都港区）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26462828
[Presentation] 細胞接着を介した膵島α細胞のグルカゴン分泌調節機構の解明2016
- Author(s)
  横川慧, 鈴木崇弘, 井上敏, 伊納義和, 鈴木亮, 古野忠秀, 平嶋尚英
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学薬学部（愛知県名古屋市）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-26462828
[Presentation] 生物発光イメージング法を用いた膵島α細胞からのグルカゴン分泌の可視化解析2016
- Author(s)
  横川慧, 鈴木崇弘, 井上敏, 伊納義和, 鈴木亮, 古野忠秀, 平嶋尚英
- Organizer
  第25回日本バイオイメージング学会学術集会
- Place of Presentation
  名古屋市立大学薬学部（愛知県名古屋市）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PROJECT-26462828
[Presentation] 哺乳類細胞における効率的なルシフェラーゼ遺伝子発現のためのコドン最適化と生物発光イメージング: 歯学研究への応用2015
- Author(s)
  鈴木崇弘, 江頭美喜, 河合逹志, 金森孝雄, 井上敏
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26462828
[Presentation] ビデオレート生物発光イメージング法による分泌型および細胞表面結合型MMP-2の可視化2012
- Author(s)
  鈴木崇弘,近藤千裕,金森孝雄,井上敏
- Organizer
  第21回日本バイオイメージング学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-08-27
- Data Source
  KAKENHI-PROJECT-23592754
[Presentation] 近赤外生物発光イメージングを目指したv-セレンテラジンの高効率合成法の開発2011
- Author(s)
  隅田有人、飯森理絵、吉田優、三浦由依子、佐藤淳一、井上敏、細谷孝充
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪国際センター
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] Concise synthesis of v-coelenterazine toward near-infrared bioluminescence imaging2011
- Author(s)
  吉田優、隅田有人、飯森理絵、三浦由依子、佐藤淳一、井上敏、細谷孝充
- Organizer
  10th International Symposium on Organic Reactions (ISOR10)
- Place of Presentation
  慶應大学矢上キャンパス(横浜)
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] 近赤外生物発光イメージングを目指したv-セレンテラジンの高効率合成法の開発2011
- Author(s)
  飯森理絵，隅田有人，吉田　優，佐原由依子，佐藤淳一，井上　敏，細谷孝充
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] MMP-2分泌のビデオレート生物発光イメージング2011
- Author(s)
  鈴木崇弘,近藤千裕,金森孝雄,井上敏
- Organizer
  第10回生命科学研究会
- Place of Presentation
  前橋
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-23592754
[Presentation] 生細胞におけるタンパク質分泌のビデオレート生物発光イメージング2011
- Author(s)
  鈴木崇弘,近藤千裕,金森孝雄,井上敏
- Organizer
  第20回記念バイオイメージング学会学術集会
- Place of Presentation
  千歳
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-23592754
[Presentation] 近赤外生物発光イメージングを目指したv-セレンテラジンの高効率合成法の開発2011
- Author(s)
  細谷孝充、飯森理絵、隅田有人、吉田優、佐原由依子、佐藤淳一、井上敏
- Organizer
  第6回日本分子イメージング学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] 新しい近赤外生物発光基質の創製を目指したv-Coelenterazine合成法の開発2011
- Author(s)
  吉田優、隅田有人、飯森理絵、三浦由依子、佐藤淳一、井上敏、細谷孝充
- Organizer
  第100回有機合成シンポジウム
- Place of Presentation
  早稲田大学大隈講堂(東京)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] 近赤外生物発光イメージングを目指したv-セレンテラジンの高効率合成法の開発2011
- Author(s)
  隅田有人，飯森理絵，吉田　優，三浦由依子，佐藤淳一，井上　敏，細谷孝充
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] ビデオレート生物発光イメージング: 遊走細胞におけるMMP-2分泌動態の可視化2011
- Author(s)
  鈴木崇弘, 近藤千裕, 金森孝雄, 井上敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23592754
[Presentation] 新しい近赤外生物発光基質の創製を目指したv-Coelenterazine合成法の開発2011
- Author(s)
  吉田　優，隅田有人，飯森理絵，三浦由依子，佐藤淳一，井上　敏，細谷孝充
- Organizer
  第100回有機合成シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] Concise synthesis of v-coelenterazine toward near-infrared bioluminescence imaging2011
- Author(s)
  吉田　優，隅田有人，飯森理絵，三浦由依子，佐藤淳一，井上　敏，細谷孝充
- Organizer
  10th International Symposium on Organic Reactions (ISOR10)
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] 近赤外生物発光イメージングを目指したv-セレンテラジンの高効率合成法の開発2011
- Author(s)
  飯森理絵、隅田有人、吉田優、佐原由依子、佐藤淳一、井上敏、細谷孝充
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京工業大学大岡山キャンパス
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-23710266
[Presentation] ビデオレート生物発光イメージング:遊走細胞におけるMMP-2分泌動態の可視化2011
- Author(s)
  鈴木崇弘,近藤千裕,金森孝雄,井上敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23592754
[Presentation] ガウシアルシフェラーゼを用いた生物発光イメージング法によるMMP-2分泌の可視化2011
- Author(s)
  鈴木崇弘,近藤千裕,金森孝雄,井上敏
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-23592754
[Presentation] ビデオレート生物発光イメージング法による分泌型および細胞表面結合型MMP-2の可視化
- Author(s)
  鈴木崇弘, 近藤千裕, 金森孝雄, 井上　敏
- Organizer
  第21回日本バイオイメージング学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23592754

1. SUZUKI Takahiro (70298545)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
2. YOSHIDA Suguru (10583750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. HOSOYA Takamitsu (60273124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 水野光政 (20609812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 古野忠秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inouye Satoshi 井上 敏

INOUYE Satoshi 井上 敏

Research Projects

Research Products

Co-Researchers

Bioluminescence imaging for osteogenic protein secretion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new coelenterazine analogue for in vivo imaging of reactive oxygen species

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bioluminescence imaging of MMP-2 and its related proteins secretion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of new substrates for near-infrared bioluminescence imaging

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Quantitative visualization of synchronized insulin secretion from 3D-cultured cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Visualization of glucagon secretion from pancreatic α cells by bioluminescence video microscopy: identification of secretion sites in the intercellular contact regions2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein expression of preferred human codon-optimized Gaussia luciferase genes with an artificial open-reading frame in mammalian and bacterial cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Codon optimization of genes for efficient protein expression in mammalian cells by selection of only preferred human codons.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unconventional secretion of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) in mammalian cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Luminescence enhancement of the catalytic 19 kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Video-rate bioluminescence imaging of protein secretion from a living cell2014

Author(s)

Journal Title

Data Source

[Journal Article] ビデオレート生物発光イメージング法によるタンパク質分泌動態の可視化2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 生物発光系によるin vivoイメージングを指向した発光基質の開発2013

Author(s)

Journal Title

Data Source

[Journal Article] Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: Comparison of substrate specificity for C2-modified coelenterazines2013

Author(s)

Journal Title

Inouye Satoshi 井上敏

INOUYE Satoshi 井上敏