Nakamura Motonao 中村元直

… Alternative Names

NAKAMURA Motonao 中村元直

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Researcher Number	40431762
Other IDs
Affiliation (Current)	2024: 岡山理科大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help	2024: 岡山理科大学, 生命科学部, 教授 2014 – 2022: 岡山理科大学, 理学部, 教授 2013: 岡山理科大学, 理学部・臨床生命科学科, 教授 2011 – 2013: 東京大学, 医学(系)研究科(研究院), 准教授 2007 – 2011: 東京大学, 大学院・医学系研究科, 准教授 … More 2010: 東京大学, 大学院・医学系・研究科, 准教授 2006: The University of Tokyo, Graduate School of Medicine, Associate Professor 2006: 東京大学, 大学院医学系研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47040:Pharmacology-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / General pharmacology Except Principal Investigator Surgical dentistry / Biological Sciences / Biofunction/Bioprocess / Pathological medical chemistry
Keywords	Principal Investigator GPCR / Gタンパク質共役型受容体 / リン酸化 / G蛋白質共役型受容体 / 細胞内輸送 / がん細胞 / 苦味受容体 / BLT1 / ロイコトリエンB4 / ユビキチン化 … More / 翻訳後修飾 / シグナル伝達 / ABCB1 / 抗がん剤耐性 / ABC-B1蛋白質 / 抗がん剤 / 異物排泄 / ガン細胞 / 有害物排出促進 / ヒトがん細胞 / 有害物質排出機構 / 皮膚細胞 / 白血球 / Gタンパク質共役型受容体タンパク質共役型受容体 / 炎症 / 好中球 / リン酸化修飾 / ロイコトリエンB４ / 情報伝達 / βアレスチン / ユビキチン修飾 / G蛋白質共役型受容体蛋白質共役型受容体 / 糖鎖修飾 / 品質管理 / 遺伝子発現 / ロイコトリエン / シャペロン / 受容体 … More Except Principal Investigator アシル転移酵素 / 質量分析計 / アシル転位酵素 / オーファン受容体 / 骨吸収性疾患 / ロイトコイエン / Gタンパク共役型受容体 / ホスホリパーゼA2 / 肺サーファクタント / 遺伝子欠損マウス / ロイコトリエン / 脂質メディエーター / 血中循環ガン細胞の単離 / 固定化細胞の光回収技術 / バイオテクノロジー / マイクロ・ナノデバイス / 受容体刺激による細胞動態解析 / 受容体の細胞内動態シミュレーション / 受容体の細胞内動態解析 / 光選択的一細胞回収 / 光選択的一細胞固定化 / 高密度一細胞アレイ / 生体膜 / メタボロミクス / 疾患モデル / エイコサノイド / リピドミクス / リン脂質 / 脂質可視化 / トリグリセリド輸送 / ドコサヘキサエン酸 / アラキドン酸 / グリセロリン脂質 / Pulmonary surfactant lipids / Metabolome / Knockout mice (or Gene-deficient mice) / G protein-coupled receptor / Phospholipase A2 / Platelet-activating factor / Acyltransferase / Lipid mediator / Gタンパク共役型受容 / ロイトコリエン / 肺サーファクタント脂質 / メタボローム / 血小板活性化因子 / 脂質 / GPCR / GPCR受容体 / 脂質リガンド / Gタンパク共益型受容体 / 脂質メタポローム / Gタンパク質共役型受容体 / ホスホリパーゼＡ２ / 脂質メタボローム / G タンパク共役型受容体 / ホスホリパーゼ A2 Less

がん細胞の多剤耐性化は細胞内苦味受容体による抗がん剤感受が起点となるPrincipal Investigator
- Principal Investigator
  
  中村元直
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Okayama University of Science
Elimination of toxic substance through the activation of bitter taste receptosrPrincipal Investigator
- Principal Investigator
  
  Nakamura Motonao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Okayama University of Science
Phosphorylations of BLT1 receptor are necessary for sufficient cell responses at high concentration of leukotriene B4Principal Investigator
- Principal Investigator
  
  Nakamura Motonao
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University of Science
Development and its applications of a versatile system for single cell array, imaging analysis and selective cell collection
- Principal Investigator
  
  Nagamune Teruyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
fundamental Study on the mechanism of GPCR trafficking to cell surfacePrincipal Investigator
- Principal Investigator
  
  Nakamura Motonao
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University of Science
Biology of diversity and asymmetry of membrane lipids
- Principal Investigator
  
  Shimizu Takao
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Center for Global Health and Medicine
  The University of Tokyo
Development of therapy targeting lipid mediator-related GPCRs for prevention of bone resorptive diseases
- Principal Investigator
  
  HIKIJI Hisako
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu Dental College
Fundamental research for quantitative control of the surface GPCRsPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Motonao
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
生理活性脂質受容体の細胞内輸送メカニズム解明Principal Investigator
- Principal Investigator
  
  中村元直
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Development of therapy targeting orphan GPCR-related lipid mediators for prevention of bone destruction
- Principal Investigator
  
  HIKIJI Hisako
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu Dental College
Phospholipid metabolism and lipid mediators
- Principal Investigator
  
  SHIMIZU Takao
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Lipid Mediators and Lipid Metaborome
- Principal Investigator
  
  SHIMIZU Takao
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] 脂質解析ハンドブック; 生理活性脂質（脂質メディエーター）2019
- Author(s)
  清水孝雄、中村元直
- Total Pages
  306
- Publisher
  羊土社
- ISBN
  9784758122412
- Data Source
  KAKENHI-PROJECT-17K08294
[Book] エリオット　生化学, 分子生物学　第５版2016
- Author(s)
  村上誠、原俊太郎、中村元直
- Total Pages
  583
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] 苦味受容体を介する有害物質排除機構の発見と創薬2023
- Author(s)
  中村元直
- Journal Title
  
  BIO Clinica
  
  Volume: 12 Pages: 108-112
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] Bitter taste receptor T2R38 is expressed on skin-infiltrating lymphocytes and regulates lymphocyte migration2022
- Author(s)
  Sakakibara Moe、Sumida Hayakazu、Yanagida Keisuke、Miyasato Sosuke、Nakamura Motonao、Sato Shinichi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 11790-11790
- DOI
  10.1038/s41598-022-15999-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08900, KAKENHI-PROJECT-20K21493
[Journal Article] Role of leukotriene B4 (LTB4)-LTB4 receptor 1 signaling in post-incisional nociceptive sensitization and local inflammation in mice2022
- Author(s)
  Asahara,M., Ito,N., Hoshino,Y., Sasaki,T., Yokomizo,T., Nakamura,M., Shimizu,T., and Yamada,Y.
- Journal Title
  
  PLOS ONE
  
  Volume: 17(10) Pages: 1-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] Constitutively active GPR43 is crucial for proper leukocyte differentiation2022
- Author(s)
  Miyasato Sosuke、Iwata Kurumi、Mura Reika、Nakamura Shou、Yanagida Keisuke、Shindou Hideo、Nagata Yosuke、Kawahara Masahiro、Yamaguchi Satoshi、Aoki Junken、Inoue Asuka、Nagamune Teruyuki、Shimizu Takao、Nakamura Motonao
- Journal Title
  
  The FASEB Journal
  
  Volume: 37 Issue: 1 Pages: 1-18
- DOI
  10.1096/fj.202201591r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11488, KAKENHI-PROJECT-20K08900, KAKENHI-PROJECT-20K21493, KAKENHI-PROJECT-23K21062
[Journal Article] Recent advances in function and structure of two leukotriene B4 receptors: BLT1 and BLT2.2022
- Author(s)
  Nakamura,M., Shimizu,T.
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 203 Pages: 1-13
- DOI
  10.1016/j.bcp.2022.115178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] 苦味受容体を起点とした皮膚組織での有害物質排除機構について2021
- Author(s)
  中村元直
- Journal Title
  
  アグリバイオ
  
  Volume: 5 Pages: 84-88
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] 皮膚組織に発現する苦味受容体について2021
- Author(s)
  中村元直
- Journal Title
  
  月刊　細胞
  
  Volume: 53
- NAID
  40022594050
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] 最近のGPCR創薬　-　GPCRの構造ゲノム創薬の発展とさらなる創薬研究にむけて2021
- Author(s)
  中村元直、堀哲哉、宮野雅司
- Journal Title
  
  月刊　脳神経内科
  
  Volume: 94 Pages: 496-506
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] 皮膚に発現する苦味受容体の発見とその生理学的意義に関する考察2021
- Author(s)
  中村元直
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41 Pages: 52-56
- Data Source
  KAKENHI-PROJECT-20K21493
[Journal Article] Leukotrienes2020
- Author(s)
  Motonao Nakamura, Takehiko Yokomizo
- Journal Title
  
  Encyclopedia of Molecular Pharmacology
  
  Volume: 11 March Pages: 1-10
- DOI
  10.1007/978-3-030-21573-6_87-1
- ISBN
  9783030215736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08294
[Journal Article] Leukotriene receptors and experience as potential therapeutic targets.2018
- Author(s)
  Yokomizo,T., Nakamura,M., and Shimizu,T
- Journal Title
  
  J.Clinical Investigation
  
  Volume: 128 Issue: 7 Pages: 2691-2701
- DOI
  10.1172/jci97946
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08294, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627
[Journal Article] Stepwise phosphorylation of leukotriene B4 receptor 1 defines cellular responses to leukotriene B4.2018
- Author(s)
  Nakanishi,Y., Tan,M., Ichiki,T., Inoue,A. Yoshihara,J., Maekawa,N., Takenoshita.I., Yanagida,K., Yamahira,S., Yamaguchi,S., Aoki,J. Nagamune,T., Yokomizo,T., Shimizu,T., and Nakamura,M
- Journal Title
  
  Science Signaling
  
  Volume: 11 (544) Issue: 544 Pages: 5390-5390
- DOI
  10.1126/scisignal.aao5390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08294, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627
[Journal Article] Real-time monitoring of pH-dependent intracellular trafficking of ovarian cancer G protein-coupled receptor 1 in living leukocytes2018
- Author(s)
  Modong Tan, Satoshi Yamaguchi, Motonao Nakamura, Teruyuki Nagamune
- Journal Title
  
  ournal of Bioscience and Bioengineering
  
  Volume: 印刷中 Issue: 3 Pages: 30031-30066
- DOI
  10.1016/j.jbiosc.2018.03.012
- NAID
  40021667194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02319, KAKENHI-PROJECT-17K08294
[Journal Article] Stepwise phosphorylation of leukotriene B4 receptor 1 defines cellular responses to leukotriene B42018
- Author(s)
  Yoshimitsu Nakanishi, Modong Tan, Takako Ichiki, Asuka Inoue, Junichi Yoshihara, Naoto Maekawa, Itsuki Takenoshita, Keisuke Yanagida, Shinya Yamahira, Satoshi Yamaguchi, Junken Aoki, Teruyuki Nagamune, Takehiko Yokomizo, Takao Shimizu, Motonao Nakamura
- Journal Title
  
  Science Signaling
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02319
[Journal Article] Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT12018
- Author(s)
  Hori Tetsuya、Okuno Toshiaki、Hirata Kunio、Yamashita Keitaro、Kawano Yoshiaki、Yamamoto Masaki、Hato Masakatsu、Nakamura Motonao、Shimizu Takao、Yokomizo Takehiko、Miyano Masashi、Yokoyama Shigeyuki
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 14 Issue: 3 Pages: 262-269
- DOI
  10.1038/nchembio.2547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-17K08294, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-18H02627
[Journal Article] Microfluidic preparation of anchored cell membrane sheets for in vitro analyses and manipulation of the cytoplasmic face2017
- Author(s)
  Izuta,S., Yamaguchi,S., Misawa,R., Yamahira,S., Tan,M., Kawahara,M., Suzuki,T., Takagi,T., Sato,K., Nakamura,M., Nagamune,T. and Okamoto,A.
- Journal Title
  
  Sci. Rep.
  
  Volume: 7:14962 Issue: 1 Pages: 14962-14962
- DOI
  10.1038/s41598-017-14737-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08294, KAKENHI-PROJECT-17K19007
[Journal Article] Quantitative image cytometry for analyzing intracellular trafficking of G protein-coupled receptors on a chemical-trapping single cell array2017
- Author(s)
  談莫東、山口哲志、山平真也、中村元直、長棟輝行
- Journal Title
  
  Lab on a Chip
  
  Volume: 印刷中 Issue: 11 Pages: 1933-1938
- DOI
  10.1039/c7lc00198c
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02319, KAKENHI-PROJECT-17K08294
[Journal Article] Quantitative image cytometry for analyzing intracellular trafficking of G protein-coupled receptors on a chemically-trapping single cell array2017
- Author(s)
  Tan,M., Yamaguchi,S., Yamahira,S., Nakamura,M. and Nagamune,T.
- Journal Title
  
  Lab on a Chip
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] 薬理学的シャペロン ; 小胞体蓄積GPCRを形質膜へ発現させる特異的リガンド2016
- Author(s)
  安田大恭,中村元直
- Journal Title
  
  特集「GPCR研究の最前線2016」,医学のあゆみ
  
  Volume: 256 Pages: 385-392
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] The atypical N-glycosylation motif, Asn-Cys-Cys, in human GPR109A is required for normal cell surface expression and intracellular signaling2015
- Author(s)
  Yasuda, D., Imura, Y., Ishii, S., Shimizu, T., and Nakamura, M.
- Journal Title
  
  FASEB J.
  
  Volume: 印刷中 Issue: 6 Pages: 2412-2422
- DOI
  10.1096/fj.14-267096
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25116703, KAKENHI-PROJECT-26860182, KAKENHI-PROJECT-26460061, KAKENHI-PROJECT-24229003
[Journal Article] Gタンパク質共役型受容体（GPCR）2015
- Author(s)
  栗原裕基, 中村元直
- Journal Title
  
  生体の科学
  
  Volume: 66 Pages: 2-3
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] The leukotriene B4 receptor BLT1 is stabilized by transmembrane helix capping mutations.2015
- Author(s)
  Hori, T., Nakamura, M., Yokomizo, T., Shimizu, T., Miyano, M.
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 4 Pages: 243-249
- DOI
  10.1016/j.bbrep.2015.09.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-24229003
[Journal Article] 薬理学的シャペロン – 小胞体蓄積GPCRを形質膜へ発現させる特異的リガンド2015
- Author(s)
  安田大恭,中村元直
- Journal Title
  
  「GPCR研究の最前線2016」, 医学のあゆみ
  
  Volume: 256 Pages: 385-392
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury2015
- Author(s)
  Asahara M, Ito N, Yokomizo T, Nakamura M, Shimizu T, Yamada Y.
- Journal Title
  
  Mol Pain
  
  Volume: 11 Pages: 1-12
- DOI
  10.1186/s12990-015-0010-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22116002, KAKENHI-PROJECT-26462377, KAKENHI-PROJECT-26460061, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-24229003
[Journal Article] The leukotriene B4 receptor BLT1 is stabilized by transmembrane helical capping mutations.2015
- Author(s)
  Hori,T., Nakamura,M., Yokomizo,T., Shimizu,T., and Miyano,M.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 4 Issue: 1 Pages: 243-249
- DOI
  10.1016/j.pep.2010.02.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] Pathogenic role of CXCR2/BLT1-driven neutrophil infiltration for induction of psoriatic skin inflammation2014
- Author(s)
  Sumida,H., Yanagida,K., Kita,Y., Abe,J., Matsushima,K., Nakamura,M., Ishii,S., Sato,S., and Shimizu,T.
- Journal Title
  
  J.Immunol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Pathogenic role of CXCR2/BLT1-driven neutrophil infiltration for induction of psoriatic skin inflammation.2014
- Author(s)
  Sumida,H., Yanagida,K., Kita,Y., Abe,J., Matsushima,K., Nakamura,M., Ishii,S., Sato,S., and Shimizu,T.
- Journal Title
  
  J.Immunol
  
  Volume: 掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Interplay between CXCR2 and BLT1 facilitates neutrophil infiltration and resultant keratinocyte activation in a murine model of imiquimod-induced psoriasis2014
- Author(s)
  Sumida, H., Yanagida, K., Kita, Y., Abe, J., Matsushima, K., Nakamura, M., Ishii, S., Sato, S., and Shimizu, T.
- Journal Title
  
  J. Immunol
  
  Volume: 192 Issue: 9 Pages: 4361-4369
- DOI
  10.4049/jimmunol.1302959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229003, KAKENHI-PUBLICLY-25116703, KAKENHI-PROJECT-26460061
[Journal Article] Visualization of the pH-dependent dynamic distribution of G2A in living cells.2014
- Author(s)
  Lan,W., Yamaguchi,S., Yamamoto,T., Yamahira,S., Tan,M., Murakami,N., Zhang,J., Nakamura,M., and Nagamune,T.
- Journal Title
  
  The FASEB Journal
  
  Volume: 28 Issue: 9 Pages: 3965-3974
- DOI
  10.1096/fj.14-252999
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460061
[Journal Article] Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.2013
- Author(s)
  Taygerly,J.P., McGee,L.R., Cushing,T.D., Li,Y., Motani,A., Chen,J-L., Frankmoelle,W., Ye,G., Learned,M.R., Jaen,J., Miao,S., Timmermans,P.B., Thoolen,M., Kearney,P., Flygare,J., Beckmann,H., Weiszmann,J., Lindstrom,M., Walker,N., Liu,J., Biermann,D., Wang,Z., Nishiu,J., and Nakamura,M
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 21 Pages: 979-992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.2013
- Author(s)
  Taygerly,J.P., Nishiu,J., and Nakamura,M.
- Journal Title
  
  Bioorganic & Medicinal Chemistry.
  
  Volume: 掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] PLA2G3, a mammalian homolog of anaphylactic phospholipase A2 in bee venom, facilitates proper maturation of mast cells through the paracrine PGD2 loop.2013
- Author(s)
  Taketomi,Y., Sakanaka,M.,Nakamura,M., Shimizu,T., Hara,S., and Murakami,M
- Journal Title
  
  Nature immunology
  
  Volume: 掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Amino acid residues of G-protein coupled receptors critical for endoplasmic reticulum export and trafficking2013
- Author(s)
  Nakamura,M., Yasuda,D., Hirota,N., Yamamoto,T., Yamaguchi,S., Shimizu,T., and Nagamune,T.
- Journal Title
  
  Methods in Enzymol
  
  Volume: 521 Pages: 203-216
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] PLA2G3, a mammalian homolog of anaphylactic phospholipase A2 in bee venom, facilitates proper maturation of mast cells through the paracrine PGD2 loop2013
- Author(s)
  Taketomi,Y., Ueno,N., Kojima,T., Kawana,M., Tanaka,S., Sakanaka,M., Nakamura,M., Sato,H., Nishito,Y., Kambe,N., Yamamoto,K., Gelb,M.H., Arita,M., Yokomizo,T.,Watanabe,K,.Nakamura,M., Shimizu,T., Hirai,H., Aritake,K., Urade,Y., Morimoto,K., Sugimoto,Y., Narumiya,S., Hara,S., and Murakami,M.
- Journal Title
  
  Nature immunology
  
  Volume: 14 Pages: 554-566
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] 特異的リガンドによる小胞体蓄積GPCRの細胞膜への搬出2013
- Author(s)
  安田大恭、中村元直
- Journal Title
  
  生化学
  
  Volume: 85
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Discovery of INT131: a selective PPARmodulator that enhances insulin sensitivity2013
- Author(s)
  Taygerly,J.P., McGee,L.R., Rubenstein,S.M., Houze,J.B., Cushing,T.D., Li,Y., Motani,A., Chen,J-L., Frankmoelle,W., Ye,G., Learned,M.R., Jaen,J., Miao,S., Timmermans,P.B., Thoolen,M., Kearney,P., Flygare,J., Beckmann,H., Weiszmann,J., Lindstrom,M., Walker,N., Liu,J., Biermann,D., Wang,Z., Hagiwara,A., Iida,T., Aramaki,H., Kitao,Y., Shinkai,H., Furukawa,N., Nishiu,J., and Nakamura,M.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 21 Pages: 979-992
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] p130Cas plays important roles in osteoclastic bone resorption2013
- Author(s)
  Nagai Y, Osawa k, Fukushima H, Tamura Y, Aoki K, Ohya K, Yasuda H, Hikiji H, Kato S, Honda H, Nakamura I, Maki K, Jimi E
- Journal Title
  
  J. Bone Miner. Res
  
  Volume: 28 Issue: 12 Pages: 2449-2462
- DOI
  10.1002/jbmr.1936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390467, KAKENHI-PROJECT-23593039, KAKENHI-PROJECT-24592774, KAKENHI-PROJECT-24659992, KAKENHI-PROJECT-24791980, KAKENHI-PROJECT-24890214, KAKENHI-PROJECT-25293377
[Journal Article] Amino acid residues of G-protein coupled receptors critical for endoplasmic reticulum export and trafficking2013
- Author(s)
  Nakamura,M., Yasuda,D., Hirota,N., Yamamoto,T., Yamaguchi,S., Shimizu,T., and Nagamune,T
- Journal Title
  
  Methods in Enzymol.
  
  Volume: 521 Pages: 203-216
- DOI
  10.1016/b978-0-12-391862-8.00011-9
- ISBN
  9780123918628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Mast cell maturation is driven via a novel group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.2013
- Author(s)
  Taketomi, Y., Morimoto, K., Murakami, M., et al., 他30名
- Journal Title
  
  Nature Immunol.
  
  Volume: (印刷中) Issue: 6 Pages: 554-63
- DOI
  10.1038/ni.2586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02074, KAKENHI-PROJECT-12J02006, KAKENHI-PROJECT-21390036, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116002, KAKENHI-PLANNED-22116003, KAKENHI-PLANNED-22116005, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-23501258, KAKENHI-PROJECT-23590067, KAKENHI-PROJECT-23590077, KAKENHI-PROJECT-23591665, KAKENHI-PROJECT-23592999, KAKENHI-PROJECT-23659044, KAKENHI-PROJECT-23790119, KAKENHI-PROJECT-23790120, KAKENHI-PUBLICLY-24117724, KAKENHI-PROJECT-24390021, KAKENHI-PROJECT-24592777, KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-25460087, KAKENHI-PROJECT-25860059
[Journal Article] Identification and characterization of a novel chemotype MEK inhibitor able to alter the phosphorylation state of MEK1/22012
- Author(s)
  Yoshida,T., Kakegawa,J., Yamaguchi,T., Hantani,Y., Okajima,N., Sakai,T., Watanabe,Y., and Nakamura,M.
- Journal Title
  
  Oncotarget
  
  Volume: 3 Pages: 1533-1545
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Disruption of group IVA cytosolic phospholipase A2 attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNFa-mediated pathway.2012
- Author(s)
  Saito, Y., Watanabe, K., Fujioka, D., Nakamura, T., Obata, J., Kawabata, K., Watanabe, Y., Mishina, H., Tamaru, S., Kita, Y., Shimizu, T., Kugiyama, K.
- Journal Title
  
  Heart Circ. Physiol.
  
  Volume: 302 Issue: 10 Pages: H2018-H2030
- DOI
  10.1152/ajpheart.00955.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage2012
- Author(s)
  Echigo,R., Shimohata,N., Karatsu,K., Yano,F., Kayasuga-Kariya,Y., Fujisawa,A., Ohto,T., Kita,Y., Nakamura,M., Suzuki,S., Mochizuki,M., Shimizu,T., Chung,U-i., and Nobuo Sasaki,N.
- Journal Title
  
  J. Translational Medicine
  
  Volume: Apr 30
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Identification and characterization of a novel chemotype MEK inhibitor able to alter the phosphorylation state of MEK1/2.2012
- Author(s)
  Yoshida,T., Kakegawa,J., Yamaguchi,T., Hantani,Y., Okajima,N., Sakai,T., Watanabe,Y., and Nakamura,M.
- Journal Title
  
  Oncotarget
  
  Volume: 3 Pages: 1533-1545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage2012
- Author(s)
  Echigo R, Shimohata N, Karatsu K, Yano F, Kayasuga-Kariya Y, Fujisawa A, Ohto T, Kita Y, Nakamura M, Suzuki S, Mochizuki M, Shimizu T, Chung UI, Sasaki N
- Journal Title
  
  J Transl Med
  
  Volume: 10 Issue: 1 Pages: 80-80
- DOI
  10.1186/1479-5876-10-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23590067, KAKENHI-PROJECT-24659665
[Journal Article] Amino acid residues of G-protein coupled receptors critical for endoplasmic reticulum export and trafficking.2012
- Author(s)
  Nakamura,M., Yasuda,D., Hirota,N., Yamamoto,T., Yamaguchi,S., Shimizu,T., and Nagamune,T.
- Journal Title
  
  Methods in Enzymology
  
  Volume: （掲載確定）
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590067
[Journal Article] 九州歯科大学新入生口腔健康診断の検討(その1)-新入生口腔健康診断の概要-2011
- Author(s)
  引地尚子, 高橋由希子, 久保田浩三, 園木一男, 村岡宏祐, 笠井宏記, 中村太志, 千綿かおる, 日高勝美, 柿木保明, 西原達次, 福田仁一
- Journal Title
  
  九州歯学会雑誌
  
  Volume: 65 Pages: 31-39
- NAID
  10029335622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390467
[Journal Article] Leukotriene Receptors2011
- Author(s)
  Nakamura,M., and Shimizu,T
- Journal Title
  
  Chem.Rev
  
  Volume: 111 Pages: 6231-6298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] 九州歯科大学新入生口腔健康診断の検討(その1) -新入生口腔健康診断の概要-2011
- Author(s)
  引地尚子, 高橋由希子, 久保田浩三, 園木一男, 村岡宏祐, 笠井宏記, 中村太志, 千綿かおる, 日高勝美, 柿木保明, 西原達次, 福田仁一
- Journal Title
  
  九州歯学会雑誌
  
  Volume: 65(2) Pages: 31-39
- NAID
  10029335622
- Data Source
  KAKENHI-PROJECT-23390467
[Journal Article] Leukotriene Receptors2011
- Author(s)
  Nakamura, M., Shimizu, T.
- Journal Title
  
  Chemical Reviews
  
  Volume: 10 掲載確定(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] 九州歯科大学新入生口腔健康診断における性格特性と口腔環境との関係2011
- Author(s)
  園木一男, 引地尚子, 井上博雅, 千綿かおる, 高橋由希子, 久保田浩三, 金久弥生, 吉野賢一, 辻澤利行, 秋房住郎, 日高勝美, 中村太志, 笠井宏記, 村岡宏, 柿木保明, 西原達次
- Journal Title
  
  九州歯科学会雑誌
  
  Volume: 65 Pages: 83-91
- NAID
  10029478789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390467
[Journal Article] Leukotriene Receptors.2011
- Author(s)
  Nakamura, M., and Shimizu, T.
- Journal Title
  
  Chem. Rev.
  
  Volume: 111 Issue: 10 Pages: 6231-6298
- DOI
  10.1021/cr100392s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] 九州歯科大学新入生口腔健康診断における性格特性と口腔環境との関係2011
- Author(s)
  園木一男, 引地尚子, 井上博雅, 千綿かおる, 高橋由希子, 久保田浩三, 金久弥生, 吉野賢一, 辻澤利行, 秋房住郎, 日高勝美, 中村太志, 笠井宏記, 村岡宏, 柿木保明, 西原達次
- Journal Title
  
  九州歯科学会雑誌
  
  Volume: 65(3) Pages: 83-91
- NAID
  10029478789
- Data Source
  KAKENHI-PROJECT-23390467
[Journal Article] Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor2010
- Author(s)
  Hirota, N., Yasuda, D., Hashidate, T., Yamamoto, T., Yamaguchi, S., Nagamune, T., Nagase, T., Shimizu, T., Nakamura, M.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 5931-5940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Specific ligands as pharmacological chaperons : The transport of misfolded G-protein coupled receptors to the cell surface2010
- Author(s)
  Nakamura, M., Yasuda, D., Hirota, N., Shimizu, T.
- Journal Title
  
  IUBMB Life (掲載確定(印刷中), in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Protective roles of the leukotriene B4 receptor BLT2 in murine inflanmmatory colitis2010
- Author(s)
  Iizuka, Y., Okuno, T., Saeki, K., Uozaki, H., Okada, S., Misaka, T., Sato, T., Toh, H., Fukayama, M., Takeda, N., Kita, Y., Shimizu, T., Nakamura, M., Yokomizo, T.
- Journal Title
  
  The FASEB Journal
  
  Volume: 24 Pages: 4678-4690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Expression, purification and characterization of leukotriene B4 receptor, BLT1 in Pichia pastoris.2010
- Author(s)
  Hori, T., Sato, Y., Takahashi, N., Takio, K., Yokomizo, T., Nakamura, M., Shimizu, T., Miyano, M.
- Journal Title
  
  Protein Expression and Purification (掲載確定(印刷中))(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Specific ligands as pharmacological chaperons : The transport of misfolded G-protein coupled receptors to the cell surface2010
- Author(s)
  Nakamura, M., Yasuda, D., Hirota, N., Shimizu, T.
- Journal Title
  
  IUBMB Life
  
  Volume: 62 Pages: 453-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor2010
- Author(s)
  Hirota, N., Yasuda, D., Hashidate, T., Yamamoto, T., Yamaguchi, S., Nagamune, T., Nagase, T., Shimizu, T., Nakamura, M.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 5931-5940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Expression, puri fication and characterization of leukotriene B_4 receptor, BLT1 in Pichia pastoris2010
- Author(s)
  Hori, T., Sato, Y., Takahashi, N., Takio, K., Yokomizo, T., Nakamura, M., Shimizu, T., Miyano, M.
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 72 Pages: 66-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor2010
- Author(s)
  Hirota, N., Yasuda, D., Hashidate, T., Yamamoto, T., Yamaguchi, S., Nagamune, T., Nagase, T., Shimizu, T., and Nakamura, M
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Issue: 8 Pages: 5931-5940
- DOI
  10.1074/jbc.m109.066282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis2010
- Author(s)
  Iizuka, Y., Okuno, T., Saeki, K., Uozaki, H., Okada, S., Misaka, T., Sato, T., Toh, H., Fukayama, M., Takeda, N., Kita, Y., Shimizu, T., Nakamura, M., Yokomizo, T.
- Journal Title
  
  FASEB J.
  
  Volume: 24 Pages: 4678-4690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Liquid chromatography/mass spectrometry analysis revealing preferential occurrence of non-arachidonate-containing phosphatidylinositol bisphosphate species in nuclei and changes in their levels during cell cycle2010
- Author(s)
  Ogiso, H., Nakamura, K., Yatomi, Y., Shimizu, T., and Taguchi, R
- Journal Title
  
  Rapid. Commun. Mass Spectrom
  
  Volume: 24 Pages: 436-442
- URL
  http://onlinelibrary.wiley.com/doi/10.1002/rcm.4415/abstract;jsessionid=78A69D3B4E51ABDE608A6EC7110D6CCE.d01t01
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor.2010
- Author(s)
  Hirota, N., Yasuda, D., Hashidate, T., Yamamoto, T., Yamaguchi, S., Nagamune, T., Nagase, T., Shimizu, T., Nakamura, M
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 5931-5940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Expression, purification and characterization of leukotriene B4 receptor, BLT1 in Pichia pastors2010
- Author(s)
  Hori, T., Sato, Y., Takahashi, N., Takio, K., Yokomizo, T., Nakamura, M., Shimizu, T., Miyano, M.
- Journal Title
  
  Protein Expr.Purif. (掲載確定(印刷中), in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Specific ligands as pharmacological chaperons : The transport of misfolded G-protein coupled receptors to the cell surface.2010
- Author(s)
  Nakamura, M., Yasuda, D., Hirota, N., Shimizu, T.
- Journal Title
  
  IUBMB Life (掲載確定(印刷中))(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] AML1 enhances the expression of leukotriene B4 type-1 receptor in peripheral leukocytes.2010
- Author(s)
  Hashidate, T., Murakami, N., Nakagawa, M., Ichikawa, M., Kurokawa, M.Shimizu, T., Nakamura, M.
- Journal Title
  
  The FASEB Journal (掲載確定(印刷中))(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis2010
- Author(s)
  Iizuka, Y., Okuno, T., Saeki, K., Uozaki, H., Okada, S., Misaka, T., Sato, T., Toh, H., Fukayama, M.,Takeda, N., Kita, Y., Shimizu, T., Nakamura, M., and Yokomizo, T.
- Journal Title
  
  FASEB J
  
  Volume: 24 Issue: 12 Pages: 4678-4690
- DOI
  10.1096/fj.10-165050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011, KAKENHI-PROJECT-22790320
[Journal Article] Liquid chromatography/mass spectrometry analysis revealing preferential occurrence of non-arachidonate-containing phosphatidylinositol bisphosphate species in nuclei and changes in their levels during cell cycle2010
- Author(s)
  Ogiso, H., Nakamura, K., Yatomi, Y., Shimizu, T., Taguchi, R.
- Journal Title
  
  Rapid.Commun.Mass Spectrom. 24
  
  Pages: 436-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] AML1 enhances the expression of leukotriene B4 type-1 receptor in peripheral leukocytes2010
- Author(s)
  Hashidate, T., Murakami, N., Nakagawa, M., Ichikawa, M., Kurokawa, M.Shimizu, T., Nakamura, M.
- Journal Title
  
  The FASEB Journal
  
  Volume: 24 Pages: 3500-3510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Transcriptional regulation of human G2A in monocytes/macrophages : involvement of c/EBPs, Runx and Pu.1.2009
- Author(s)
  Murakami, N., Harayama, T., Hashidate, T., Yokomizo, T., Shimizu, T., Nakamura, M.
- Journal Title
  
  Genes to Cells 14
  
  Pages: 1441-1455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Helix 8 of leukotriene B4 type-2 receptor is required for the folding to pass the quality control in the endoplasmic reticulum.2009
- Author(s)
  Yasuda, D., Okuno, T., Yokomizo, T., Hori, T., Hirota, N., Hashidate.T., Miyano, M., Shimizu, T., Nakamura, M
- Journal Title
  
  The FASEB Journal 23
  
  Pages: 1470-1481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659060
[Journal Article] Transcriptional regulation of human G2A in monocytes/macrophages : involvement of c/EBPs, Runx and Pu.12009
- Author(s)
  Murakami, N., Hashidate, T., Harayama, T., Yokomizo, T., Shimizu, T., Nakamura, M.
- Journal Title
  
  Genes Cells 14
  
  Pages: 1441-1455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Helix 8 of leukotriene B4 type-2 receptor is required for the folding to pass the quality control in the endoplasmic reticulum2009
- Author(s)
  Yasuda, D., Okuno, T., Yokomizo, T., Hori, T., Hirota, N., Hashidate, T., Miyano, M., Shimizu, T., and Nakamura, M
- Journal Title
  
  FASEB J
  
  Volume: 23 Issue: 5 Pages: 1470-1481
- DOI
  10.1096/fj.08-125385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Helix 8 of leukotriene B4 type-2 receptor is required for the folding to pass the ER quality control.2009
- Author(s)
  Yasuda, D., Okuno, T., Yokomizo, T., Hori, T., Hirota, N., Hashidate, T., Miyano, M., Shimizu, T., Nakamura, M.
- Journal Title
  
  FASEB J. 23
  
  Pages: 1470-1481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins2008
- Author(s)
  Hase, M., Yokomizo, T., Shimizu, T., and Nakamura, M
- Journal Title
  
  J. Biol. Chem
  
  Volume: 283 Issue: 19 Pages: 12747-12755
- DOI
  10.1074/jbc.m709487200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins.2008
- Author(s)
  Hase, M., Yokomizo, T., Shimizu, T., and Nakamura, M.
- Journal Title
  
  J. Biol. Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] Reduced pain behaviors and ERK activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor.2007
- Author(s)
  Tsuda, M., Ishii, S., Masuda, T., Hasegawa, S., Nakamura, K., Nagata, K., Yamashita, T., Furue, H., Tozaki-Saito, H., Yoshimura, M., Koizumi, S., Shimizu, T., and Inoue, K.
- Journal Title
  
  J. Neurochem. 102
  
  Pages: 1658-1668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011
[Journal Article] B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2.2003
- Author(s)
  Tashiro, S., Sumi, T., Uozumi, N., Shimizu, T., Nakamura, T.
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 17715-17722
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Presentation] ロイコトリエンB4受容体をユビキチン修飾する責任リガーゼの諸性質について2022
- Author(s)
  森脇大貴, 立巳莉子, 中村元直
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] β3-アドレナリン受容体のTrp64Arg変異体の性状解析2022
- Author(s)
  松元悠, 宮里奏佑, 中村元直
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ロイコトリエンB4第一受容体へのβ-アレスチンのリクルートに関する最近の知見について2022
- Author(s)
  立巳莉子, 森脇大貴, 井上飛鳥, 青木淳賢, 中村元直
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] HL-60細胞の顆粒球様分化におけるGPR43の生理学的意義について2022
- Author(s)
  宮里奏佑, 柴田祥希, 中村元直
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 短鎖脂肪酸受容体GPR43の細胞内局在や恒常活性を規定する領域について2022
- Author(s)
  柴田祥希, 宮里奏佑, 中村元直
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ヒト表皮角化細胞株（HaCaT）に発現する苦味受容体の情報伝達機構について2022
- Author(s)
  森爽々波, 真鍋光, 井上飛鳥, 青木淳賢, 中村元直
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 苦味受容体T2R38によるリンパ球遊走制御2022
- Author(s)
  榊原萌, 住田隼一, 柳田圭介, 宮里奏佑, 中村元直, 佐藤伸一
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 白血球における短鎖脂肪酸受容体GPR43の発現意義に関する研究2021
- Author(s)
  宮里奏佑、中村元直
- Organizer
  2021日本生化学会中四国支部会大会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ヒト表皮角化細胞株（HaCaT）に発現する苦味受容体の機能解析について2021
- Author(s)
  森爽々波、宮本拓実、真鍋光、中村元直
- Organizer
  第94回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] がん細胞株における苦味受容体の機能に関する研究2021
- Author(s)
  宮本拓実、森爽々波、眞鍋光、中村元直
- Organizer
  第94回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ロイコトリエン B4受容体の細胞内移行におけるユビキチン修飾の関与について2021
- Author(s)
  森脇大貴、谷口梨奈、森脇瑞貴、中村元直
- Organizer
  第94回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 2種類の合成リガンドを活用した短鎖脂肪酸受容体GPR43の機能解析について2021
- Author(s)
  宮里奏佑、中村元直
- Organizer
  2021年度日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 血球系細胞に発現する２つの短鎖脂肪酸受容体の特徴について2021
- Author(s)
  宮里奏佑、武良麗華、中村聖、河原正浩、山口哲志、中村元直
- Organizer
  第63回日本脂質生化学会大会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 白血球に発現する2つの短鎖脂肪酸受容体、GPR41とGPR43の機能的差異に関する研究2021
- Author(s)
  宮里奏佑、武良麗華、井上飛鳥、青木淳賢、中村元直
- Organizer
  第94回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ロイコトリエンB４第一受容体（BLT1）のリン酸化修飾に関する研究～責任キナーゼの決定とリン酸化の意義について2021
- Author(s)
  立巳莉子、相原咲希、井上飛鳥、青木淳賢、中村元直
- Organizer
  第94回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ロイコトリエンB４第一受容体（BLT1）が受けるリン酸化修飾のヒエラルキーについて2020
- Author(s)
  相原咲希、森脇瑞貴、谷口梨奈、森脇大貴、井上飛鳥、青木淳賢、中村元直
- Organizer
  第93回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ロイコトリエンB４受容体（BLT1）のユビキチン修飾に関わる責任ユビキチンリガーゼについて2020
- Author(s)
  谷口梨奈、森脇瑞貴、相原咲希、森脇大貴、中村元直ロイコトリエンB４受容体（BLT1）のユビキチン修飾に関わる責任ユビキチンリガーゼについて
- Organizer
  第93回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] 顆粒球様に分化したHL60細胞に発現する2つの短鎖脂肪酸受容体の機能的差異について2020
- Author(s)
  岩田久瑠実、宮里奏佑、武良麗華、中村聖、河原正浩、山口哲志、中村元直
- Organizer
  第93回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ヒト表皮角化細胞に発現する苦味受容体について2020
- Author(s)
  真鍋光、真田恵、宮本拓実、榊原萌、住田隼一、中村元直
- Organizer
  第93回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] ヒト皮膚細胞における苦味受容体の生理学的機能の解明2020
- Author(s)
  真鍋光、真田恵、中村元直
- Organizer
  日本生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] がん細胞株に発現する苦味受容体に関する研究2020
- Author(s)
  宮本拓実、真田恵、眞鍋光、中村元直
- Organizer
  第93回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K21493
[Presentation] シャペロン薬を含めたGPCRを標的とした創薬研究について2019
- Author(s)
  中村元直
- Organizer
  日経バイオテクプロフェッショナルセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ロイコトリエンB４受容体の翻訳後修飾とその意義について2019
- Author(s)
  森脇瑞貴、谷口梨奈、竹之下逸樹、相原咲希、中村元直
- Organizer
  日本生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 苦味受容体は異物排出のためのセンサーとして働くのか？2019
- Author(s)
  真田恵、瀬川美奈、菊池彩花、眞鍋光、中村元直
- Organizer
  日本生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ロイコトリエンB４受容体のリン酸化修飾とユビキチン修飾の連関について2019
- Author(s)
  森脇瑞貴、谷口梨奈、竹之下逸樹、相原咲希、中村元直
- Organizer
  第92回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 細胞内に局在する苦味受容体の機能解析について2019
- Author(s)
  真田恵、眞鍋光、菊池彩花、瀬川美奈、宮本拓実、中村元直
- Organizer
  第92回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ヒト表皮角化細胞であるHaCaT株に内在的に発現する苦味受容体の機能について2019
- Author(s)
  真鍋光、真田恵、菊池彩花、瀬川美奈、中村元直
- Organizer
  第92回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] N型糖鎖に非依存的な小胞体内品質管理について～糖鎖修飾の無いGPCRを材料とした解析2019
- Author(s)
  久保田佳純、熊谷早織、中村元直
- Organizer
  第92回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] HL60細胞に発現する2つの短鎖脂肪酸受容体（GPR41、GPR43）の機能的差異に関する研究2019
- Author(s)
  岩田久瑠実、河北麻衣、山崎慎太郎、中村元直
- Organizer
  第92回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 25種類のヒト苦味受容体の中でTAS2R4が持つ特異な特徴について2018
- Author(s)
  ◯ 瀬川美奈、菊池彩花、真田恵、真鍋光、前川直斗、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ロイコトリエンB４受容体のリン酸化修飾に関する解析～昨年からの続報2018
- Author(s)
  ◯ 竹之下逸樹、相原咲希、井上飛鳥、青木淳賢、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 短鎖脂肪酸受容体であるGPR41とGPR43のHL60細胞における発現2018
- Author(s)
  ◯ 岩田久瑠実、河北麻衣、中野花菜、佐伯美樹、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] N型糖鎖修飾を持たないGPCRの小胞体内での品質管理について2018
- Author(s)
  ◯ 久保田佳純、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 皮膚系細胞株に発現する苦味受容体の機能について2018
- Author(s)
  ◯ 真鍋光、瀬川美奈、菊池彩花、山本千晶、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 25種類のヒト苦味受容体のホモ/ヘテロ２量体形成に関する研究2018
- Author(s)
  ◯ 真田恵、瀬川美奈、菊池彩花、前川直斗、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ロイコトリエンB４受容体のユビキチン化修飾に関する解析2018
- Author(s)
  ◯ 森脇瑞貴、谷口梨奈、小田未那美、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 苦味受容体TAS2R38の配列多様性が機能に与える影響について2018
- Author(s)
  ◯ 菊池彩花、瀬川美奈、真田恵、真鍋光、前川直斗、中村元直
- Organizer
  第91回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] LTB4/BLT１を介した情報伝達におけるBLT１リン酸化の意義2017
- Author(s)
  竹之下逸樹、伊藤千尋、前川直斗、中村元直
- Organizer
  Combio 2017
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ヒト由来の血球系細胞株における苦味受容体の発現2017
- Author(s)
  山本千晶、前川直斗、藤原友幹、中村元直
- Organizer
  日本組織培養学会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] TGFα切断アッセイ系を活用したロイコトリエンB4受容体のシグナル伝達解析について2017
- Author(s)
  瀬川美奈、井上飛鳥、青木淳賢、中村元直
- Organizer
  Combio 2017
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] 味細胞以外の細胞におけるヒト苦味受容体の発現とその局在について2017
- Author(s)
  前川直斗、山本千晶、藤原友幹、中村元直
- Organizer
  Combio 2017
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ヒト血球系細胞株における25種類の苦味受容体の発現解析2017
- Author(s)
  山本千晶、前川直斗、藤原友幹、中村元直
- Organizer
  日本組織培養学会
- Place of Presentation
  岡山（岡山理科大学）
- Year and Date
  2017-06-30
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] ヒト苦味受容体の味細胞以外の組織での発現について～株化口内細胞における発現解析2017
- Author(s)
  前川直斗、山本千晶、藤原友幹、中村元直
- Organizer
  日本組織培養学会
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ヒト苦味受容体遺伝子配列の多型解析2017
- Author(s)
  菊池彩花、西田愛、金城夢乃、井上知邑、中村元直
- Organizer
  Combio 2017
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ヒト皮膚由来細胞株に発現する苦味受容体の解析2017
- Author(s)
  山本千晶、前川直斗、藤原友幹、中尾榛花、中村元直
- Organizer
  Combio 2017
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] ヒト苦味受容体の味細胞以外の組織での発現について～株化口内細胞における発現解析2017
- Author(s)
  前川直斗、山本千晶、藤原友幹、中村元直
- Organizer
  日本組織培養学会
- Place of Presentation
  岡山（岡山理科大学）
- Year and Date
  2017-06-30
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] Phosphorylations of BLT1 receptor: necessary for sufficient cell responses at high concentration of LTB42017
- Author(s)
  中村元直
- Organizer
  日本組織培養学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08294
[Presentation] Phosphorylations of BLT1 receptor: necessary for sufficient cell responses at high concentration of LTB42017
- Author(s)
  中村元直
- Organizer
  日本組織培養学会
- Place of Presentation
  岡山（岡山理科大学）
- Year and Date
  2017-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] 25種類の苦味受容体のヒト血球系細胞株での発現解析2016
- Author(s)
  山本千晶、前川直斗、藤原友幹、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  仙台（東北大学）
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] ヒトの株化口内細胞における苦味受容体の発現解析2016
- Author(s)
  前川直斗、山本千晶、藤原友幹、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  仙台（東北大学）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] GPCRを標的としたドラッグスクリーニングのためのイメージサイトメトリー技術の開発2016
- Author(s)
  談　莫東, 山口哲志, 山平真也, 中村元直, 長棟輝行
- Organizer
  2016年度生物工学若手研究者の集い（若手会）夏のセミナー
- Place of Presentation
  ホテルコンチネンタル府中（東京都府中市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-15H02319
[Presentation] Development of the image cytometry method to analyze g-protein coupled receptor kinetics in the cell.2015
- Author(s)
  Modong Tan, Shinya Yamahira, Satoshi Yamaguchi, Motonao Nakamura, Teruyuki Nagamune
- Organizer
  The international chemical congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawall, USA
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] Development of the image cytometry method to analyze G-protein coupled receptor kinetics in the cell2015
- Author(s)
  Modong Tan, Shinya Yamahira, Satoshi Yamaguchi, Motonao Nakamura and Teruyuki Nagamune
- Organizer
  2015 環太平洋国際化学会議（Pacifichem 2015）
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02319
[Presentation] 一細胞アレイを用いたpH応答性GPCRの細胞内動態解析2015
- Author(s)
  談莫東、山口哲志、山平真也、中村元直、長棟輝行
- Organizer
  日本生物工学会大会
- Place of Presentation
  鹿児島県鹿児島市
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] 一細胞アレイを用いたpH応答性GPCRの細胞内動態解析2015
- Author(s)
  談莫東, 山口哲志, 山平真也, 中村元直,長棟輝行
- Organizer
  第67回日本生物工学会大会
- Place of Presentation
  城山観光ホテル (鹿児島県鹿児島市)
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15H02319
[Presentation] 膜リン脂質代謝と脂質メディエーター受容体の新展開2013
- Author(s)
  中村元直、清水孝雄
- Organizer
  2012年度日本農芸化学会大会、シンポジウム
- Place of Presentation
  京都
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] Identification of amino acid residues responsible for basal and ligand-induced phosphorylations of human leukotriene B4 type 1 receptor by Phos-tag SDS-PAGE2013
- Author(s)
  Yoshimitsu Nakanishi, Keisuke Yanagida, Takao Shimizu, and Motonao Nakamura
- Organizer
  Bioactive Lipids in Cancer, Inflammation, and Related Diseases
- Place of Presentation
  San Juan, Puerto Rico
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] イミキモド誘発マウス乾癬様皮疹における好中球浸潤の機序と役割の解明2013
- Author(s)
  住田隼一、柳田圭介、北芳博、阿部淳、松島綱治、中村元直、石井聡、佐藤伸一、清水孝雄
- Organizer
  第41回日本臨床免疫学会総会
- Place of Presentation
  海峡メッセ下関、日本(山口県)、下関市
- Data Source
  KAKENHI-PROJECT-24229003
[Presentation] Analysis of human leukotriene B4 type 1 receptor phosphorylation sites by Phos-tag SDS-PAGE"Bioactive Lipids in Cancer, Inflammation, and Related Diseases2013
- Author(s)
  Yoshimitsu Nakanishi, Keisuke Yanagida, Takao Shimizu, and Motonao Nakamura
- Organizer
  13th International Conference
- Place of Presentation
  San Juan, Puerto Rico
- Year and Date
  2013-11-04
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] ニコチン酸受容体GPR109Aが有するN型糖鎖付加のための非sequon配列の重要性について2012
- Author(s)
  安田大恭、井村裕己、石井聡、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  福岡(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] N型糖鎖修飾がないα2Bアドレナリン受容体の小胞体内品質管理について2012
- Author(s)
  歌代奈和、井村祐己、安田大恭、石浦章一、清水孝雄、中村元直
- Organizer
  日本生化学会大会合同大会　2012　（ポスター発表）
- Place of Presentation
  福岡国際会議場　マリンメッセ福岡(日本・福岡市）
- Data Source
  KAKENHI-PROJECT-24229003
[Presentation] Phos-tag SDS-PAGE法を用いたロイコトリエンB４第一受容体(BLT1)におけるリン酸化部位の解析2012
- Author(s)
  中西由光、清水孝雄、中村元直
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡国際会議場　福岡県
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] 膜リン脂質代謝と脂質メディエーター受容体の新展開2012
- Author(s)
  中村元直、清水孝雄
- Organizer
  日本農芸化学会シンポジウム(招待講演)
- Place of Presentation
  京都女子大（京都府）
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] Phos-tag SDS-PAGE法を用いたロイコトリエンB４第一受容体(BLT1)におけるリン酸化部2012
- Author(s)
  中西由光、清水孝雄、中村元直
- Organizer
  日本生化学会大会合同大会　2012　（ポスター発表）
- Place of Presentation
  福岡国際会議場　マリンメッセ福岡(日本・福岡県）
- Data Source
  KAKENHI-PROJECT-24229003
[Presentation] ニコチン酸受容体GPR109aが有するN型糖鎖付加のための非sequon配列の重要性について2012
- Author(s)
  安田大恭、井村祐己、石井聡、清水孝雄、中村元直
- Organizer
  日本生化学会大会合同大会　2012　（口演）
- Place of Presentation
  福岡国際会議場　マリンメッセ福岡(日本・福岡県）
- Data Source
  KAKENHI-PROJECT-24229003
[Presentation] N型糖鎖修飾がないα2Bアドレナリン受容体の小胞体内品質管理について2012
- Author(s)
  歌代奈和、井村祐己、安田大恭、石浦章一、清水孝雄、中村元直
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡国際会議場　福岡県
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] Phos-tag SDS-PAGE法を用いたロイコトリエンB4第一受容体(BLT1)におけるリン酸化部位の解析2012
- Author(s)
  中西由光、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  福岡(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] ニコチン酸受容体GPR109aが有するN型糖鎖付加のための非sequon配列の重要性について2012
- Author(s)
  安田大恭、井村祐己、石井聡、清水孝雄、中村元直
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡国際会議場　福岡県
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] N型糖鎖がないα2Bアドレナリン受容体の小胞体内品質管理について2012
- Author(s)
  歌代奈和、井村裕己、安田大恭、石浦章一、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  福岡(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] 九州歯科大学新入生口腔健康診断の検討(その1)-新入生口腔健康診断の概要-2011
- Author(s)
  引地尚子, 高橋由希子, 久保田浩三, 園木一男, 村岡宏祐, 笠井宏記, 中村太志, 千綿かおる, 日高勝美, 柿木保明, 西原達次, 福田仁一
- Organizer
  第71回九州歯科学会総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23390467
[Presentation] 結晶化のためのロイコトリエンB4受容体(BLT1)の熱安定性と抗BLT1モノクローナル抗体の作製2011
- Author(s)
  堀哲也、菅原光明、中村元直，横溝岳彦，清水孝雄、宮野雅司
- Organizer
  日本生化学会年会
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] 九州歯科大学新入生口腔健康診断の検討(その1 )-新入生口腔健康診断の概要-2011
- Author(s)
  引地尚子, 高橋由希子, 久保田浩三, 園木一男, 村岡宏祐, 笠井宏記, 中村太志, 千綿かおる, 日高勝美, 柿木保明, 西原達次, 福田仁一
- Organizer
  第71回九州歯科学会総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23390467
[Presentation] ロイコトリエンB4第一受容体の遺伝子発現調節機構の解明2011
- Author(s)
  吉田（橋立）智美、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] G蛋白質共役型受容体ファミリーにおけるN型糖鎖修飾の小胞体搬出に及ぼす影響2011
- Author(s)
  井村祐己、清水孝雄，中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] G蛋白質共役型受容体ファミリーにおけるN型糖鎖修飾の小胞体搬出に及ぼす影響2011
- Author(s)
  井村祐己、清水孝雄,中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  京都(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] 結晶化のためのロイコトリエンB4受容体(BLT1)の熱安定性と抗BLT1モノクローナル抗体の作製2011
- Author(s)
  堀哲也、菅原光明、中村元直,横溝岳彦,清水孝雄、宮野雅司
- Organizer
  日本生化学会年会
- Place of Presentation
  京都(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] 短鎖脂肪酸を認識するG蛋白質共役型受容体の血球内での発現制御に関する解析2011
- Author(s)
  宮崎陽造、吉田（橋立）智美、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] 短鎖脂肪酸を認識するG蛋白質共役型受容体の血球内での発現制御に関する解析2011
- Author(s)
  宮崎陽造、吉田(橋立)智美、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  京都(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] ロイコトリエンB4第一受容体の遺伝子発現調節機構の解明2011
- Author(s)
  吉田(橋立)智美、清水孝雄、中村元直
- Organizer
  日本生化学会年会
- Place of Presentation
  京都(国際会議場)
- Data Source
  KAKENHI-PROJECT-23590067
[Presentation] Quantity and quality regulation of leukotriene B4 receptors2010
- Author(s)
  Nakamura, M., Hashidate, T.Yasuda, D., Shimizu, T.
- Organizer
  Keystone Simposia
- Place of Presentation
  京都ウエスティン都ホテル(京都府京都市)
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] Importance of Helix 8 for ER Export of Leukotriene B_4 type-2 Receptor2010
- Author(s)
  Yasuda, D., Hirota, N., Hashidate, T., Shimizu, T., Nakamura, M.
- Organizer
  ASBMB 2010
- Place of Presentation
  Anaheim Convention Center (Anaheim, USA)
- Year and Date
  2010-04-26
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] 結晶化に向けたロイコトリエンB4受容体の大量発現と精製法の確立2010
- Author(s)
  堀哲哉、佐藤陽、横溝岳彦、中村元直、清水孝雄, 宮野雅司
- Organizer
  2010年度日本分子生物学会合同年会(BMB2010)
- Place of Presentation
  神戸ポートピアアイランドホテル(兵庫県神戸市)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] Quantity and quality regulation of leukotriene B4 receptors2010
- Author(s)
  中村元直
- Organizer
  Keystone Symposia : Bioactive Lipids : Biochemistry and Diseases 2010
- Place of Presentation
  ウェスティン都ホテル京都(京都府、日本)(ポスター発表)
- Data Source
  KAKENHI-PROJECT-19002011
[Presentation] Requirement of conserved amino acid residues residues_for ER-export and recycli ng of platelet-activating factor receptor2010
- Author(s)
  Nakamura, M., H irota, N., Yasuda, D., Hashidate, T., Yamamoto, T., Yamaguchi, S., Nagamune, T., Shimizu, T.
- Organizer
  ASBMB 2010
- Place of Presentation
  Anaheim Convention Center (Anabeim, USA)
- Year and Date
  2010-04-26
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] HL60細胞におけるロイコトリエンB4第-受容体の転写制御2010
- Author(s)
  橋立智美、清水孝雄、中村元直
- Organizer
  2010年度日本分子生物学会合同年会(BMB2010)
- Place of Presentation
  神戸ポートピアアイランドホテル(兵庫県神戸市)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] The expression of leukotriene B_4 type-1 receptor, BLT1, is facilitated by AML1 in leukocytes2010
- Author(s)
  Hashidate, T., Murakami, N., Shimizu, T., Nakamura, M.
- Organizer
  ASBMB 2010
- Place of Presentation
  Anaheim Convention Center (Anaheim, USA)
- Year and Date
  2010-04-26
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] Roles of 12-HHT/LTB4 receptor, BLT2 in murine inflammatory colites2010
- Author(s)
  奥野利明、飯塚佳子、佐伯和子、清水孝雄、中村元直、横溝岳彦
- Organizer
  2010年度日本分子生物学会合同年会(BMB2010)
- Place of Presentation
  神戸ポートピアアイランドホテル(兵庫県神戸市)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] GPR109a受容体の非典型的な配列に付加するN型糖鎖修飾の重要性2010
- Author(s)
  安田大恭、清水孝雄、中村元直
- Organizer
  2010年度日本分子生物学会合同年会(BMB2010)
- Place of Presentation
  神戸ポートピアアイランドホテル(兵庫県神戸市)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] 2つのロイコトリエンB4受容体におけるN型糖鎖修飾の意義2009
- Author(s)
  安田大介、清水孝雄、中村元直
- Organizer
  2009年度、第82回日本生化学会年会
- Place of Presentation
  神戸神戸ポートピアアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] Requirement of Helix8 for ER export of leukotriene B4 type-2 receptor.2009
- Author(s)
  Daisuke Yasuda, Toshiaki Okuno, Takehiko Yokomizo, Nobuaki Hirota, Tomomi Hashidate, Takao Shimizu, Motonao Nakamura
- Organizer
  The 5th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  東京National Center of Science
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] 白血球走化因子ロイコトリエンB4受容体であるBLT1の遺伝子発現制御2009
- Author(s)
  橋立智美、村上尚加、清水孝雄、中村元直
- Organizer
  2009年度、第82回日本生化学会年会
- Place of Presentation
  神戸神戸ポートピアアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21659060
[Presentation] Reduced local inflammation affected the attenuation of pain behavior following formalin injection in BLT1 deficiency mice
- Author(s)
  Miho Asahara, Nobuko Ito, Yoshitsugu Yamada, Takehiko Yokomizo, Motonao Nakamura, and Takao Shimizu
- Organizer
  The International Association for the Study of Pain (国際疼痛学会)
- Place of Presentation
  Buenos Aires, Argentina
- Year and Date
  2014-10-06 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-26460061
[Presentation] Analysis of human leukotriene B4 type I receptor phosphorylation sites by Phos-tag SDS-PAGE
- Author(s)
  Yoshimitsu Nakanishi, Keisuke Yanagida, Takao Shimizu, Motonao Nakamura
- Organizer
  13th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases
- Place of Presentation
  Sheraton Puerto Rico Hotel , Puerto Rico, San Juan
- Data Source
  KAKENHI-PROJECT-24229003

1. SHIMIZU Takao (80127092)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
2. KITA Yoshihiro (20401028)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. SHINDOU Hideo (10401027)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. TAKAHASHI Toshie (80236299)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. HIKIJI Hisako (50292876)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. NISHIHARA Tatsuji (80192251)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. ISHII Satoshi (10300815)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. TAKAHASH Yukiko (10582778)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. YANAGIDA Keisuke (00583882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. HAMANO Fumie (80548511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKATO Tsuyoshi (90171454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOYAMA Hiroyuki (10241994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOKUOKA Suzumi (60511376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HISHIKAWA Daisuke (10569966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YOSHIDA Tomomi (30610216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HARAYAMA Takeshi (50610218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Nagamune Teruyuki (20124373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
18. OHTSU Makoto (30361330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMAGUCHI Satoshi (80398106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
20. 福田仁一 (00106270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 田口良 (20080210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 奥野利明 (60361466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 魚住尚紀 (70313096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 谷口雅彦 (70260346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 横溝岳彦 (60302840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. 河原正浩 (50345097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NAGATA Yosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 矢野文子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Motonao 中村 元直

NAKAMURA Motonao 中村 元直

Research Projects

Research Products

Co-Researchers

がん細胞の多剤耐性化は細胞内苦味受容体による抗がん剤感受が起点となるPrincipal Investigator

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Elimination of toxic substance through the activation of bitter taste receptosrPrincipal Investigator

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Phosphorylations of BLT1 receptor are necessary for sufficient cell responses at high concentration of leukotriene B4Principal Investigator

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Development and its applications of a versatile system for single cell array, imaging analysis and selective cell collection

Principal Investigator

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fundamental Study on the mechanism of GPCR trafficking to cell surfacePrincipal Investigator

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Biology of diversity and asymmetry of membrane lipids

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Development of therapy targeting lipid mediator-related GPCRs for prevention of bone resorptive diseases

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Fundamental research for quantitative control of the surface GPCRsPrincipal Investigator

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生理活性脂質受容体の細胞内輸送メカニズム解明Principal Investigator

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Development of therapy targeting orphan GPCR-related lipid mediators for prevention of bone destruction

Principal Investigator

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Phospholipid metabolism and lipid mediators

Principal Investigator

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Lipid Mediators and Lipid Metaborome

Principal Investigator

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[Book] 脂質解析ハンドブック; 生理活性脂質（脂質メディエーター）2019

Author(s)

Total Pages

Nakamura Motonao 中村元直

NAKAMURA Motonao 中村元直

[Book] エリオット　生化学, 分子生物学　第５版2016

[Journal Article] 最近のGPCR創薬　-　GPCRの構造ゲノム創薬の発展とさらなる創薬研究にむけて2021