RYU Katsuyaku 劉克約

Researcher Number	40432637
Affiliation (based on the past Project Information) *help	2017 – 2021: 岡山大学, 医歯薬学総合研究科, 非常勤研究員 2016 – 2017: 岡山大学, 医歯薬学総合研究科, 助教 2014 – 2015: 岡山大学, 大学院医歯薬学総合研究科, 助教 2011 – 2015: 岡山大学, 医歯(薬)学総合研究科, 助教 2014: 岡山大学, 医歯薬総合研究科, 助教 2013: 岡山大学, 医歯薬学総合研究科, 助教 2007 – 2012: Okayama University, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Applied pharmacology Except Principal Investigator General pharmacology / Applied pharmacology / Basic Section 49010:Pathological biochemistry-related / Biological pharmacy / Cerebral neurosurgery
Keywords	Principal Investigator HMGB1 / 抗体医薬 / 血液脳関門 / 脳梗塞 / 脳浮腫 / 抗体治療 / 薬物治療学 / 硬膜外出血 / 脳出血 / 脳血管攣縮 … More / 硬膜下出血 / 脳内出血 / 遅発性血管攣縮 / 出血性脳卒中 / 血液ー脳関門 / 血液-脳関門 / 霊長類動物 / 炎症 / ミクログリア … More Except Principal Investigator HMGB1 / HRG / 炎症 / 抗体医薬 / 脳浮腫 / 高ヒスチジン糖タンパク / 敗血症 / 慢性炎症 / ミクログリア / 脳外傷 / 血液脳関門 / 胎盤形成 / 妊娠高血圧 / 血圧 / 妊娠 / 高血圧 / 高ヒスチジン血漿タンパク / 胎盤 / 血管リモデリング / トロホブラスト / 妊娠高血圧症候群 / 生活習慣病 / 遺伝子発現 / 肝 / DAMPs / 血漿タンパク / 急性炎症 / トランスレーションリサーチ / 蛋白質 / ARDS / Immunothrombus / トランスレーショナルリサーチ / 薬理学 / マクロファージ分化 / 骨髄ニッチ / 血管新生 / マクローファージ分化 / マクロファージ / 血管内皮細胞 / 組織修復機構 / ホメオダイナミクス / 神経細胞 / アストロサイト / 神経 / AGE / RAGE / アミロイドβ / アルツハイマー / high mobility group box1 / 抗HMGB1抗体 / 高血圧症 / SHR / High mobility group box1 / 脳腫瘍 / 脊髄損傷 / グリチルリチン / 抗腫瘍薬 / 薬物治療学 / 血液-脳関門 / アストログリア細胞 / 脳血管透過性 / 中枢・末梢神経 / LTP Less

Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Okayama University
Functional characterization of histidine-rich glycoprotein (HRG) under the inflammatory conditions.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Therapeutic Potential of an Anti-High Mobility Group Box1 Monoclonal Antibody in Hemorrhagic strokePrincipal Investigator
- Principal Investigator
  
  RYU katsuyaku
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Research for homeodynamics regeneration-promoting drug discovery
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kindai University
Mechanism for microthrombus formation on NETosis and development of therapy for ARDS.
- Principal Investigator
  
  Nishibori Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
A novel pathological mechanism of Alzheimer's disease as a chronic inflammation through RAGE signal activity.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Drug development for brain and spinal cord trauma targeting HMGB1
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
Basic scientific research for formulating drugs for treatment of hypertension
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kinki University
Development of monoclonal antibodies therapy for cerebral infarction and cerebral edema in primate animal modePrincipal Investigator
- Principal Investigator
  
  RYU katsuyaku
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Development oftherapy for acute traumatic brain injury
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Okayama University
The development of broad-spectrum antitumor agents with anti-HMGB1 antibody and clarification of its action mechanism
- Principal Investigator
  
  WAKE HIDENORI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Mechanism for HMGB-or HMGB1-derived peptide-induced increase in BBB permeability
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
Development of monoclonal antibodies therapy for cerebral infarction and cerebral edemaPrincipal Investigator
- Principal Investigator
  
  RYU Katsuyaku
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
脳浮腫の発生機序解明と創薬標的の同定
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Development of antibody therapy for brain infarctionPrincipal Investigator
- Principal Investigator
  
  RYU Katsuyaku
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
虚血性脳障害と学習・記憶過程に共通する原理の探索研究
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University

[Journal Article] Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions.2020
- Author(s)
  Watanabe M, Toyomura T, Tomiyama M, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S.
- Journal Title
  
  Mol Biol Rep.
  
  Volume: 47(9) Issue: 9 Pages: 7153-7159
- DOI
  10.1007/s11033-020-05783-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K06807, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K14969
[Journal Article] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes2020
- Author(s)
  Wang Dengli、Liu Keyue、Fukuyasu Yusuke、Teshigawara Kiyoshi、Fu Li、Wake Hidenori、Ohtsuka Aiji、Nishibori Masahiro
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 3 Pages: 643-643
- DOI
  10.3390/cells9030643
- NAID
  120006860110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] Differential contribution of possible pattern‐recognition receptors to advanced glycation end product?induced cellular responses in macrophage‐like RAW264.7 cells2019
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: in press Issue: 2 Pages: 265-272
- DOI
  10.1002/bab.1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-18K06807
[Journal Article] Histidine-rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF-κB and MAPK signal pathway2019
- Author(s)
  Gao S, Wake H, Gao Y, Wang D, Mori S, Liu K, Teshigawara K, Takahashi H, Nishibori M
- Journal Title
  
  Br J Pharmacol.
  
  Volume: 176 Issue: 15 Pages: 2808-2824
- DOI
  10.1111/bph.14711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17K15580
[Journal Article] Histidine-Rich Glycoprotein Suppresses Hyperinflammatory Responses of Lung in a Severe Acute Pancreatitis Mouse Model2018
- Author(s)
  Terao K, Wake H, Adachi N, Liu K, Teshigawara K, Takahashi H, Mori S, Nishibori M
- Journal Title
  
  Pancreas
  
  Volume: 47 Issue: 9 Pages: 1156-1164
- DOI
  10.1097/mpa.0000000000001153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-17K15580, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] The C‐terminal region of tumor necrosis factor like weak inducer of apoptosis is required for interaction with advanced glycation end products2018
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: 66 Issue: 2 Pages: 254-260
- DOI
  10.1002/bab.1706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-18K06807
[Journal Article] Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions.2018
- Author(s)
  Zhong H, Wake H, Liu K, Gao Y, Teshigawara K, Sakaguchi M, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 136(3) Issue: 3 Pages: 97-106
- DOI
  10.1016/j.jphs.2017.11.003
- NAID
  130007902144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K15580
[Journal Article] Evidence of a role for spinal HMGB1 in ischemic stress-induced mechanical allodynia in mice.2018
- Author(s)
  Matsuura W, Harada S, Liu K, Nishibori M, Tokuyama S.
- Journal Title
  
  Brain Res
  
  Volume: 15;1689 Pages: 1-10
- DOI
  10.1016/j.brainres.2018.02.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-16K10988
[Journal Article] Inter-α inhibitor proteins maintain neutrophils in a resting state by regulating shape and reducing ROS production.2018
- Author(s)
  Htwe SS, Wake H, Liu K, Teshigawara K, Stonestreet BS, Lim YP, Nishibori M.
- Journal Title
  
  Blood Adv.
  
  Volume: 2(15) Issue: 15 Pages: 1923-1934
- DOI
  10.1182/bloodadvances.2018018986
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats.2017
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Journal Title
  
  Sci Rep.
  
  Volume: 7:46243. Issue: 1 Pages: 46243-46243
- DOI
  10.1038/srep46243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response2017
- Author(s)
  Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: 印刷中 Issue: 1-2 Pages: 153-162
- DOI
  10.1007/s11010-017-3045-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06785, KAKENHI-PROJECT-15K08605, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
[Journal Article] Metformin Directly Binds the Alarmin HMGB1 and Inhibits its Proinflammatory Activity.2017
- Author(s)
  Horiuchi T, Sakata N, Narumi Y, Kimura T, Hayashi T, Nagano K, Liu K, Nishibori M, Tsukita S, Yamada T, Katagiri H, Shirakawa R, Horiuchi H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 印刷中 Issue: 20 Pages: 8436-8446
- DOI
  10.1074/jbc.m116.769380
- NAID
  120006331939
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19000, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-26293215, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-16K15486
[Journal Article] The specific localization of advanced glycation end-products (AGEs) in rat pancreatic islets.2017
- Author(s)
  Morioka Y, Teshigawara K, Tomono Y, Wang D, Izushi Y, Wake H, Liu K, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 134(4) Issue: 4 Pages: 218-224
- DOI
  10.1016/j.jphs.2017.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
[Journal Article] Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice.2017
- Author(s)
  Watanabe H, Watanabe KS, Liu K, Hiramatsu S, Zeggar S, Katsuyama E, Tatebe N, Akahoshi A, Takenaka F, Hanada T, Akehi M, Sasaki T, Sada KE, Matsuura E, Nishibori M, Wada J.
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 6 Pages: 31-39
- DOI
  10.1016/j.omtm.2017.05.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-16K19600
[Journal Article] Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy.2017
- Author(s)
  Zhao J, Wang Y, Xu C, Liu K, Wang Y, Chen L, Wu X, Gao F, Guo Y, Zhu J, Wang S, Nishibori M, Chen Z.
- Journal Title
  
  Brain Behavior and Immunity
  
  Volume: 64 Pages: 308-319
- DOI
  10.1016/j.bbi.2017.02.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Journal Article] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2017
- Author(s)
  Fu L, Liu K, Wake H, Teshigawara K, Yoshino T, Takahashi H, Mori S, Nishibori M.
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1):1179. Issue: 1 Pages: 1179-1179
- DOI
  10.1038/s41598-017-01325-y
- NAID
  130007901378
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
[Journal Article] Macrophage-derived HMGB1 as a Pain Mediator in the Early Stage of Acute Pancreatitis in Mice: Targeting RAGE and CXCL12/CXCR4 Axis.2017
- Author(s)
  Irie Y, Tsubota M, Ishikura H, Sekiguchi F, Terada Y, Tsujiuchi T, Liu K, Nishibori M, Kawabata A.
- Journal Title
  
  Journal of Neuroimmune Pharmacology
  
  Volume: 12 Issue: 4 Pages: 693-707
- DOI
  10.1007/s11481-017-9757-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08909
[Journal Article] Phagocytosis of Advanced Glycation End Products (AGEs) in Macrophages Induces Cell Apoptosis.2017
- Author(s)
  Gao Y, Wake H, Morioka Y, Liu K, Teshigawara K, Shibuya M, Zhou J, Mori S, Takahashi H, Nishibori M.
- Journal Title
  
  Oxid Med Cell Longev.
  
  Volume: 2017:8419035 Issue: 1 Pages: 8419035-8419035
- DOI
  10.1155/2017/8419035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
[Journal Article] Anti-high mobility group box-1 (HMGB1) antibody attenuates delayed cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats2016
- Author(s)
  Haruma J, Teshigawara K, Hishikawa T, Wang D, Liu K, Wake H, Mori S, Takahashi HK, Sugiu K, Date I, Nishibori M.
- Journal Title
  
  Scientific reports
  
  Volume: 6 Issue: 1 Pages: 37755-37768
- DOI
  10.1038/srep37755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] HMGB1 Translocation After Ischemia in the Ovine Fetal Brain.2016
- Author(s)
  Zhang J, Klufas D, Manalo K, Adjepong K, Davidson JO, Wassink G, Bennet L, Gunn AJ, Stopa EG, Liu K, Nishibori M, Stonestreet BS.
- Journal Title
  
  J Neuropathol Exp Neurol.
  
  Volume: 75(6) Issue: 6 Pages: 527-538
- DOI
  10.1093/jnen/nlw030
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Journal Article] Peripheral HMGB1-induced hyperalgesia in mice: redox state-dependent distinct roles of RAGE and TLR42016
- Author(s)
  Yamasoba, D., Tsubota, M., Domoto, R., Sekiguchi, F., Nishikawa, H., Liu, K., Nishibori, M., Ishikura, H., Yamamoto, T., Taga, A., Kawabata, A.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 130 Issue: 2 Pages: 139-142
- DOI
  10.1016/j.jphs.2016.01.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460710, KAKENHI-PROJECT-16K08909
[Journal Article] Histidine-rich glycoprotein prevents septic lethality through regulation of immunothrombosis and inflammation.2016
- Author(s)
  Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakaguchi M, Kuroda K, Gao Y, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H, Nishibori M.
- Journal Title
  
  EBioMedicine
  
  Volume: 9 Pages: 180-194
- DOI
  10.1016/j.ebiom.2016.06.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
[Journal Article] Soluble form of the receptor for advanced glycation end-products attenuates inflammatory pathogenesis in a rat model of lipopolysaccharide-induced lung injury.2016
- Author(s)
  Izushi Y, Teshigawara K, Liu K, Wang D, Wake H, Takata K, Yoshino T, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: S1347-8613(16)00026-8. Issue: 4 Pages: 1-9
- DOI
  10.1016/j.jphs.2016.02.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
[Journal Article] Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats2016
- Author(s)
  Nishida, T., Tsubota, M., Kawaishi, Y., Yamanishi, H., Kawakami, N., Sekiguchi, F., Ishikura, H., Liu, K., Nishibori, M., Kawabata, A.
- Journal Title
  
  Toxocology
  
  Volume: 365 Pages: 48-58
- DOI
  10.1016/j.tox.2016.07.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460710, KAKENHI-PROJECT-16K08909
[Journal Article] Possible involvement of the HMGB1/RAGE signaling mechanism in the induction of central post-stroke pain induced by acute global cerebral ischemia.2016
- Author(s)
  Harada S, Matsuura W, Liu K, Nishibori M, Tokuyama S.
- Journal Title
  
  Brain Res.
  
  Volume: 1646 Pages: 433-440
- DOI
  10.1016/j.brainres.2016.06.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-16K10988
[Journal Article] Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle.2015
- Author(s)
  Niwa A, Nishibori M, Hamasaki S, Kobori T, Liu K, Wake H, Mori S, Yoshino T, Takahashi H.
- Journal Title
  
  Brain Structure & Function
  
  Volume: 印刷中 Issue: 3 Pages: 1863-2653
- DOI
  10.1007/s00429-015-0995-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-26350918
[Journal Article] Suppression of peritoneal thickening by histamine in a mouse model of peritoneal scraping2014
- Author(s)
  Liu K, Yorozuya T, Adachi N, Motoki A, Ninomiya K, Mabuchi H, Iwamoto N, Nishibori M
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 19 Issue: 4 Pages: 1342-1751
- DOI
  10.1007/s10157-014-1027-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1-RAGE interaction.2014
- Author(s)
  Okuma Y, Liu K, Wake H, Liu R, Nishimura Y, Hui Z, Teshigawara K, Haruma J, Yamamoto Y, Yamamoto H, Date I, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 85 Pages: 18-26
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590337
[Journal Article] Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1-RAGE interaction.2014
- Author(s)
  OkumaY, Liu K, Wake H, Liu R, Nishimura Y, Zhong H, Teshigawara K, Haruma J, Yamamoto Y, Yamamoto H, Date I, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 85 Pages: 18-26
- DOI
  10.1016/j.neuropharm.2014.05.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461335, KAKENHI-PROJECT-25670464, KAKENHI-PROJECT-26293323
[Journal Article] Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury2013
- Author(s)
  Okuma Y, Wang F, Toyoshima A, Kameda M, Hishikawa T, Tokunaga K, Sugiu K, Liu K, Haruma J, Nishibori M, Yasuhara T, Date I
- Journal Title
  
  Neurosci Letters
  
  Volume: 554 Pages: 156-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes2013
- Author(s)
  Takahashi H、Sadamori H、Teshigawara K、Niwa A、Liu K、Wake H、Mori S、Yoshino T、Nishibori M
- Journal Title
  
  Eur J Phamacol
  
  Volume: Vol.718、No.1-3 Issue: 1-3 Pages: 305-313
- DOI
  10.1016/j.ejphar.2013.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23790601, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590672, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461947, KAKENHI-PROJECT-25670464
[Journal Article] Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes2013
- Author(s)
  Takahashi H1, Sadamori H, Teshigawara K, Niwa A, Liu K, Wake H, Mori S, Yoshino T, Nishibori M
- Journal Title
  
  EuropeanJournalofPharmacology
  
  Volume: 718(1-3) Pages: 305-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1.2013
- Author(s)
  Nakamura Y, Morioka N, Abe H, Zhang FF, Nakashima KH, Liu K, Nishibori M, Nakata Y.
- Journal Title
  
  PLOS ONE
  
  Volume: 8(8) Issue: 8 Pages: e73640-e73640
- DOI
  10.1371/journal.pone.0073640
- NAID
  120005702487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390061
[Journal Article] Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-12013
- Author(s)
  Nakamura Y1, Morioka N, Abe H, Zhang FF, Hisaoka-Nakashima K, Liu K, Nishibori M, Nakata Y
- Journal Title
  
  PLoS One
  
  Volume: 8(8)
- NAID
  120005702487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury2013
- Author(s)
  Okuma Y, Wang F, Toyoshima A, Kameda M, Hishikawa T, Tokunaga K, Sugiu K, Liu K, Haruma J, Nishibori M, Yasuhara T, Date I
- Journal Title
  
  Neurosci Lett
  
  Volume: 554 Pages: 156-61
- DOI
  10.1016/j.neulet.2013.08.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390349, KAKENHI-PROJECT-23791602, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-25860912, KAKENHI-PROJECT-25861277
[Journal Article] Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes2013
- Author(s)
  Kohka Takahashi H, Sadamori H, Liu K, Wake H, Mori S, Yoshino T, Yamamoto Y, Yamamoto H, Nishibori M
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 701(1-3) Issue: 1-3 Pages: 194-202
- DOI
  10.1016/j.ejphar.2012.11.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-24590672
[Journal Article] Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes2013
- Author(s)
  Takahashi HK,Sadamori H, Liu K, Wake H, Mori S, Yoshino T, Yamamoto Y, Yamamoto H,Nishibori M.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 701 Pages: 194-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590337
[Journal Article] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012
- Author(s)
  Okuma Y, Liu K, Wake H, Zhang J, Maruo T, Date I, Yoshino T, Ohtsuka A, Otani N, Tomura S, Shima K, Yamamoto Y, Yamamoto H, Takahashi H K, Mori S, Nishibori M
- Journal Title
  
  Annals of Neurology
  
  Volume: 72 Issue: 3 Pages: 373-384
- DOI
  10.1002/ana.23602
- NAID
  130004427993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390349, KAKENHI-PROJECT-23659430, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-24590672
[Journal Article] Anti-High Mobility Group Box-1 Antibody Therapy for Traumatic Brain Injury2012
- Author(s)
  Okuma Y., Liu K., Wake H., Zhang J., Maruo T., Date I., Yoshio T., Ohtsuka A., Otani N., Tomura S., Shima K., Yamamoto Y., Yamamoto H., Takahashi H., Mori S.,Nishibori M
- Journal Title
  
  Annals of Neurology
  
  Volume: in press
- NAID
  130004427993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Reduction of the infarct size by simultaneous administration of l-histidine and diphenhydramine in ischaemic rat brains.2011
- Author(s)
  Adachi N, Liu K, Ninomiya K, Matsuoka E, Motoki A, Irisawa Y, Nishibori M
- Journal Title
  
  Resuscitation
  
  Volume: 82(2) Pages: 219-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier from Ischemia-Induced Disruption in Rats.2011
- Author(s)
  Zhang J, Liu K, Wake H, Nishibori M. et al.(11名、11番目)
- Journal Title
  
  Stroke
  
  Volume: 42(5) Pages: 1420-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Deleterious Role of Anti-high Mobility Group Box 1 Monoclonal Antibody in Retinal Ischemia- reperfusion Injury.2011
- Author(s)
  Yang H, Hirooka K, Liu Y, Fujita T, Fukuda K, Nakamutra T, Itano T, Zhang J, Nishibori M, Shiraga F
- Journal Title
  
  Current Eye Research
  
  Volume: 36(11) Pages: 1037-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Reduction of the infarct size by simultaneous administration of l-histidine and diphenhydramine in ischaemic rat brains.2011
- Author(s)
  Adachi N, Liu K, Nishibori M., et al.(7名、7番目)
- Journal Title
  
  Resuscitation
  
  Volume: 82(2) Pages: 219-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats2011
- Author(s)
  Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M
- Journal Title
  
  Stroke
  
  Volume: 42(5) Pages: 1420-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E-Deficient Mice.2011
- Author(s)
  Kanellakis P, Liu K, Nishibori M, et al.(11名、10番目) Bobik A.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(2) Pages: 313-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Bobik A. High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E-Deficient Mice.2011
- Author(s)
  Kanellakis P, Agrotis A, Kyaw TS, Koulis C, Ahrens I, Mori S, Takahashi HK, Liu K, Peter K, Nishibori M
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32(2) Pages: 313-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoproteine-deficient mice2011
- Author(s)
  Kanellakis P, Agrotis A, Kyaw TS, Koulis C, Ahrens I, Mori S, Takahashi HK, Liu K, Peter K, Nishibori M, Bobik A
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(2) Pages: 313-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier from Ischemia-Induced Disruption in Rats.2011
- Author(s)
  Zhang J, Takahashi HK, Liu K, Wake K, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M.
- Journal Title
  
  Stroke
  
  Volume: 42(5) Pages: 1420-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Beta2-adrenoceptor stimulation inhibits advanced glycation end products-induced adhesion molecule expression and cytokine production in human peripheral bloodmononuclear cells2010
- Author(s)
  Takahashi HK, Mori S, Liu K, Wake H, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 627(1-3) Pages: 313-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Histamine inhibits adhesion molecule expression in human monocytes, induced by advanced glycation end products, during the mixed lymphocyte reaction.2010
- Author(s)
  Zhang J, Liu K, Wake H, Nishibori M., et al.(11名、11番目)
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Pages: 1378-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in human monocytes2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Nishibori M, et al., (8名、8番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 332 Pages: 1013-1021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction2010
- Author(s)
  Takahashi HK, Zhang J, Mori S, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 34(3) Pages: 964-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Advanced glycation end products enhance monocyte activation during human mixedlymphocyte reaction2010
- Author(s)
  Ohashi K, Takahashi HK, Mori S, Liu K, Wake H, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M, Tanaka N
- Journal Title
  
  Clin Immunol
  
  Volume: 134(3) Pages: 345-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Ciprofloxacin inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2010
- Author(s)
  Mori S, Liu K, Wake H, Nishibori M., et al.(8名、8番目)
- Journal Title
  
  Br J Pharmacol
  
  Volume: 161 Pages: 229-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction.2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Nishibori M., et al.(11名、11番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 334 Pages: 964-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction.2010
- Author(s)
  Ohashi K, Liu K, Wake H, Nishibori M, et al., (11名、10番目)
- Journal Title
  
  Clin Immunol
  
  Volume: 134 Pages: 345-353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Anti-Sp100 antibody2010
- Author(s)
  Mori S, Wake H, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Nihon Rinsho
  
  Volume: 68 Suppl 6 Pages: 711-3
- NAID
  40017181877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in humanmonocytes2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 332(3) Pages: 1013-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding.2009
- Author(s)
  Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M.
- Journal Title
  
  Acta Med Okayama. 63(4)
  
  Pages: 203-211
- NAID
  120002312782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther 330(1)
  
  Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 331(2) Pages: 656-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Therapeutic effect of anti-nucleokine monoclonal antibody on ischemic braininfarction2009
- Author(s)
  Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 129(1) Pages: 25-31
- NAID
  110007028557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Prostaglandins E2 inhibits advanced glycation end products-induced adhesion molecule expression, cytokine production and lymphocyte proliferation in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Liu K, Wake H, Nishibori M, et al., (8名、8番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 331 Pages: 656-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Therapeutic effect of anti-nucleokine monoclonal antibody on ischemic brain infarction2009
- Author(s)
  Mori S, Liu K, Takahashi HK, Nishibori M.
- Journal Title
  
  Yakugaku Zasshi 129(1)
  
  Pages: 25-31
- NAID
  110007028557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes2009
- Author(s)
  Wake H, Takahashi HK, Mori S, Liu K, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330(3) Pages: 826-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Wake H, Liu K, Nishibori M, et al., (10名、10番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330 Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330(1) Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2009
- Author(s)
  Wake H, Takahashi HK, Liu K, Nishibori M, et al., (6名、6番目)
- Journal Title
  
  J. Pharmacol Exp Ther
  
  Volume: 330 Pages: 826-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding2009
- Author(s)
  Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M
- Journal Title
  
  Acta Med Okayama
  
  Volume: 63(4) Pages: 203-11
- NAID
  120002312782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] High mobility group box 1 complexed with heparin induced angiogenesis in a matrigelplug assay2009
- Author(s)
  Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Acta Med Okayama
  
  Volume: 63(5) Pages: 249-62
- NAID
  120002312983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Histidine-rich glycoprotein inhibited high mobility group box 1 in complex with heparin-induced angiogenesis in matrigel plug assay2009
- Author(s)
  Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 623(1-3) Pages: 89-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Effects of HMGB1 on ischemia reperfusion injury in the rat heart2008
- Author(s)
  Oozawa S, Mori S, Kanke T, Takahashi H, Liu K, Tomono Y, Asanuma M, Miyazaki I, Nishibori M
- Journal Title
  
  Sano S Circ J 72(7)
  
  Pages: 1178-84
- NAID
  110006792076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] ラット中脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の治療効果2008
- Author(s)
  劉克約、森秀治、高橋英夫、西堀正洋
- Journal Title
  
  岡山医学会雑誌第120巻第3号
  
  Pages: 271-277
- NAID
  130004903140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Suppression of ischaemia-induced cytokine release by dimaprit and amelioration of liver injury in rats2008
- Author(s)
  Motoki A, Adachi N, Liu K, Takahashi HK, Nishibori M, Yorozuya T, Arai T, Nagaro T
- Journal Title
  
  Basic Clin Pharmacol Toxicol 102(4)
  
  Pages: 394-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells2008
- Author(s)
  Hamano R, Takahashi HK, Iwagaki H, Kanke T, Liu K, Yoshino T, Sendo T, Nishibori M, Tanaka N
- Journal Title
  
  Shock 29(2)
  
  Pages: 154-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Alleviation of ischemia-induced brain edema by activation of the central histaminergic system in rats2008
- Author(s)
  Irisawa Y, Adachi N, Liu K, Arai T, Nagaro T
- Journal Title
  
  J Pharmacol Sci 108(1)
  
  Pages: 112-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] The immunosuppressive effects of nicotine during human mixed lymphocyte reaction2007
- Author(s)
  Takahashi HK, Iwagaki H, Hamano R, Kanke T, Liu K, Sadamori H, Yagi T, Yoshino T, Tanaka N, Nishibori M
- Journal Title
  
  Eur J Pharmacol 559(1)
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Recovery of brain dopamine metabolism by branched-chain amino acids in rats with acute hepatic failure2007
- Author(s)
  Deshpande G, Adachi N, Liu K, Motoki A, Mitsuyo T, Nagaro T, Arai T
- Journal Title
  
  J Neurosurg Anesthesiol 19(4)
  
  Pages: 243-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Effect of adenosine receptor subtypes stimulation on mixed lymphocyte reaction2007
- Author(s)
  Takahashi HK, Iwagaki H, Hamano R, Kanke T, Liu K, Sadamori H, Yagi T, Yoshino T, Sendo T, Tanaka N, Nishibor M
- Journal Title
  
  Eur J Pharmacol 564(1-3)
  
  Pages: 204-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction2007
- Author(s)
  Takahashi HK, Iwagaki H, Yagi T, Kanke T, Liu K, Yoshino T, Tanaka N, Nishibori M
- Journal Title
  
  Clin Immunol 123(3)
  
  Pages: 324-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats.2007
- Author(s)
  Liu K, et. al.
- Journal Title
  
  FASEB Journal 21
  
  Pages: 3904-3916
- NAID
  130004903140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats.2007
- Author(s)
  Liu K, et. al.
- Journal Title
  
  FASEB Journal 21
  
  Pages: 3904-3916
- NAID
  130004903140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659061
[Journal Article] Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats2007
- Author(s)
  Liu K, Mori S, Takahashi HK, Tomono Y, Wake H, Kanke T, Sato Y, Hiraga N, Adachi N, Yoshino T, Nishibori M.
- Journal Title
  
  FASEB J 21(14)
  
  Pages: 3904-16
- NAID
  130004903140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Anti-High Mobility Group Box-1 Antibody Therapy for Traumatic Brain Injury
- Author(s)
  Okuma Y., Liu K., Wake H., Nishibori M., et al.(16名、16番目)
- Journal Title
  
  Annals of Neurology
  
  Volume: (in press)
- NAID
  130004427993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] THERAPEUTIC AGENT, METHOD OF TREATMENT AND METHOD FOR PREDICTING THE SEVERITY OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME(SIRS), DISEASES CAUSED OR ACCOMPANIED BY NEUTROPHIL ACTIVATION2016
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約、勅使川原匡　他3名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 好中球活性化に起因する疾患の治療薬及び検査方法2015
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約　ほか2名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] インフルエンザ治療剤2014
- Inventor(s)
  西堀正洋、劉克約、塚原宏一、森島恒雄、八代将登、野坂宜之
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-12-26
- Data Source
  KAKENHI-PROJECT-24590658
[Patent] インフルエンザ治療剤2014
- Inventor(s)
  西堀正洋、劉克約、塚原宏一、森島恒雄、八代将登、野坂宜之
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-265514
- Filing Date
  2014-12-26
- Data Source
  KAKENHI-PROJECT-24390061
[Patent] THERAPEUTIC AGENT, TREATMENT METHOD AND TEST METHOD FOR DISEASES ASSOCIATED WITH ACTIVATION OF NEUTROPHILS2012
- Inventor(s)
  西堀正洋森秀治和氣秀徳高橋英夫劉克約勅使川匡原等
- Industrial Property Rights Holder
  西堀正洋森秀治和氣秀徳高橋英夫劉克約勅使川匡原等
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-06
- Acquisition Date
  2013-12-12
- Overseas
- Data Source
  KAKENHI-PROJECT-24590658
[Patent] 好中球活性化調節剤2012
- Inventor(s)
  西堀正洋,森秀治,和氣秀徳,髙橋英夫,劉克約,勅使河原匡
- Industrial Property Rights Holder
  西堀正洋,森秀治,和氣秀徳,髙橋英夫,劉克約,勅使河原匡
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-129232
- Filing Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-24590337
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590594
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  国立大学法人岡山大学、医療法人創和会
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21659141
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  国立大学法人岡山大学
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21659141
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  国立大学法人岡山大学
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21590594
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  国立大学法人岡山大学、医療法人創和会
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] アデローム動脈硬化抑制剤2009
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、友野靖子、足立尚登、劉克約
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2009-223472
- Filing Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] マウス周産期における血漿高ヒスチジン糖タンパクの生理的動態解析2021
- Author(s)
  勅使川原匡、劉克約、王登莉、和氣秀徳、森秀治、髙橋英夫、西堀正洋
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.2021
- Author(s)
  Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Hidenori Wake, Shuji Mori, Hideo Kohka Takahashi, Masahiro Nishibori
- Organizer
  The 22nd World Congress of International Society for the Study of Hypertension in Pregnancy (ISSHP2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 終末糖化産物結合因子の探索研究とAGEs-RAGE結合遮断領域の同定2020
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の効果2020
- Author(s)
  吉井将哲、和氣秀徳、勅使川原匡、王登莉、劉克約、髙橋陽平、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] LPS エンドトキシン血症マウスに対する抗酸化ストレス抗体の保護効果2020
- Author(s)
  喬寒棟、高尚澤、和気秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 胎盤形成と妊娠期高血圧における血漿高ヒスチジン糖タンパクの生理的役割の解析2020
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、森秀治、髙橋英夫、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 終末糖化産物はラクトフェリンに結合し，ラクトフェリン誘導性TNF-α発現応答を抑制する2019
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本薬理学会 (大阪、2019年3月14日-16日)
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019
- Author(s)
  Shangze Gao, Hidenori Wake, Sakaguchi Masakiyo, Dengli Wang, Shuji Mori, Keyue Liu, Kiyoshi Teshigawara, Yuan Gao, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧の病態解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会（大阪、2019年3月14日-16日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] AGEs結合因子の分子同定と炎症性サイトカイン発現応答への影響2019
- Author(s)
  森秀治、渡邊政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本分子生物学会年会（福岡、2019年12月3-6日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] HRGの作用により球状化したヒト好中球の貪食機能解析2019
- Author(s)
  高橋陽平、和氣秀徳、吉井將哲、阪口政清、劉克約、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 炎症誘発活性を有する新規AGEs結合分子の同定2019
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Roles of innate immune molecules in repeated stress-induced neuronal and behavioral changes.2019
- Author(s)
  Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Masahiro Nishibori, Tomoyuki Furuyashiki.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] インターアルファインヒビタータンパクは好中球形態を制御し、活性酸素分子種産生を抑制することによって好中球の静穏状態を維持する2019
- Author(s)
  HTWE SOE SOE、和氣秀徳、劉克約、勅使川原匡、Stonestreet Barbara S.、Lim Yow-Pin、西堀正洋
- Organizer
  日本薬理学会（大阪、2019年3月14日-16日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] マウス反復社会挫折ストレスによる社会忌避行動の誘導におけるHMGB1の役割2019
- Author(s)
  北岡志保、友廣彩夏、請島慎也、劉克約、和氣秀徳、勅使川原匡、西堀正洋、古屋敷智之
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧、及び、胎盤形成異常の解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本内分泌学会（仙台、2019年5月9日-11日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 終末糖化産物による炎症応答と細胞増殖応答2019
- Author(s)
  豊村隆男、渡邊政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本分子生物学会年会（福岡、2019年12月3-6日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] AGEs と炎症関連分子の共存が炎症反応に与える変化の検討2019
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会（大阪、2019年11月23日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 周産期における高ヒスチジン糖タンパク（HRG）の生理的役割の解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019
- Author(s)
  Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Advanced glycation end products interact with lactoferrin, and change the lactoferrin-stimulated proinflammatory cytokine response.2019
- Author(s)
  Shuji Mori, Masahiro Watanabe, Hidenori Wake, Kiyoshi Teshigawara, Keyue Liu, Hideo Takahashi, Masahiro Nishibori, Takao Toyomura.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 血管内皮細胞のHMGB1信号経路におけるHistidine-rich glycoproteinの阻止作用2019
- Author(s)
  高尚澤、和気秀徳、高遠、王登莉、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会（大阪、2019年3月14日-16日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 高ヒスチジン糖タンパク（histidine-rich glycoprotein）遺伝子欠損マウスの妊娠期表現型の解析2018
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（広島、2018年6月1日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Effects of inter-alpha inhibitor proteins (IAIP) on neutrophil functions.2018
- Author(s)
  Htwe SS, Wake H, Liu K, Teshigawara K, Stonestreet BS, Lim YP.
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Characterization of histidine-rich glycoprotein (HRG) production under the experimental pathological conditions.2018
- Author(s)
  Kiyoshi Teshigawara, Atsuko Niwa, Hidenori Wake, Dengli Wang, Keyue Liu, Shuji Mori, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Pathophysiological role of a factor affecting AGEs-RAGE interaction on endothelial cell responses.2018
- Author(s)
  Shuji Mori, Masahiro Watanabe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-High Mobility Group Box-1 Antibody Therapy Might Prevent Cognitive Dysfunction After Traumatic Brain Injury.2018
- Author(s)
  Yu Okuma, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Hideo K Takahashi, Nobuyuki Hirotsune, Shigeki Nishino, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective effect of histidine rich glycoprotein (HRG) on human vascular endothelial cells.2018
- Author(s)
  Gao Y, Wake H, Liu K, Teshigawara K, NishiboriM.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 遺伝子改変細胞を用いたDAMPs分子の作用メカニズム解析2018
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会（広島、2018年6月1日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb therapy for intracerebral hemorrhage-induced brain injury in rats.2018
- Author(s)
  Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018
- Author(s)
  Hidenori Wake, Shuji Mori, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Yuan Gao, Hideo K Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧症候群様表現型の解析2018
- Author(s)
  勅使川原匡、劉克約、兼森玄、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（神戸、2018年11月23日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018
- Author(s)
  Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Specific action mediated by spinal HMGB1 receptors in the induction of central post-stroke pain.2018
- Author(s)
  Matsuura W, Harada S, Liu K, Nishibori M, Tokuyama S.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Protective effects of Histidine-rich glycoprotein on human vascular endothelial cells.2018
- Author(s)
  Yuan Gao, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2018
- Author(s)
  Nishibori M, Fu L, Wake H, Wang D, Teshigawara K, Liu K, Takahashi HK, Mori S.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 炎症惹起因子HMGB1の糖代謝制御に対する生理的役割の検討2018
- Author(s)
  兼森玄、勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] AGEs-TWEAK相互作用による炎症応答の制御2018
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本生化学会（京都、2018年9月24-26日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb therapy for intracerebral hemorrhage-induced brain injury in rats.2018
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018
- Author(s)
  Wake H, Mori S, Teshigawara K, Liu K, Wang D, Gao Y, Takahashi HK, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 抗HMGB1抗体による脳内出血の治療2018
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Effects of inter-alpha inhibitor proteins (IAIP) on neutrophil functions.2018
- Author(s)
  Htwe SS, Wake H, Liu K, Teshigawa K, Stonestreet BS, Lim YP, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 高ヒスチジン糖タンパク（histidine-rich glycoprotein, HRG）と結合親和性をもつ炎症関連血漿タンパクの探索解析2018
- Author(s)
  勅使川原匡、丹羽淳子、衷輝、和氣秀徳、劉克約、王登莉、高橋英夫、森秀治、西堀正洋
- Organizer
  日本生化学会（京都、2018年9月24-26日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Effects of Histidine-Rich Glycoprotein on Erythrocyte Aggregation and Hemolysis: Implications for a Role under Septic Conditions.2018
- Author(s)
  Hui Zhong, Hidenori Wake, Keyue Liu, Yuan Gao, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Shuji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 脊椎HMGB1関連受容体/グリア細胞/NOSシグナルを介する脳卒中後疼痛の発現機序の解明2018
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018
- Author(s)
  Shangze Gao, Yuan Gao, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Shiji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The analysis of anxiety-and depression-related behaviors in neuropathic pain of mice possible involvement of brain inflammation.2018
- Author(s)
  Hisaoka-Nakashima K, Tomimura Y, Yoshii T, Zhang FF, Nakamura Y, Liu K, Nishibori M, Nakata Y, Morioka N.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Anti-high mobility group box-1 antibody therapy might prevent cognitive dysfunction after traumatic brain injury.2018
- Author(s)
  Okuma Y, Liu K, Wake H, Teshigawara K, Mori S, Takahashi HK, Hirotsune N, Nishino S, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] The effects of histidine-rich glycoprotein on neutrophil-like differentiated cell lines.2018
- Author(s)
  Yukinori Yoshii, Hidenori Wake, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Yohei Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] ダメージ関連分子HMGB1の糖代謝制御への関与の検討2018
- Author(s)
  兼森玄、勅使川原匡、劉克約、和氣秀徳、王登莉、高橋英夫、森秀治、西堀正洋
- Organizer
  西日本医学生学術フォーラム2018（三重、2018年12月15日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 脳卒中後疼痛に対する脊髄HMGB1およびその関連受容体の関与2018
- Author(s)
  松浦歩、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 炎症惹起因子HMGB1の糖代謝制御に対する生理的役割の検討2018
- Author(s)
  兼森玄、勅使川原匡、劉克約、和氣秀徳、王登莉、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（神戸、2018年11月23日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] HMGB1 translocation induced by histamine in vascular endothelial cells in vitro2018
- Author(s)
  Nishibori M, Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S.
- Organizer
  World Histamine Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2018
- Author(s)
  Masahiro Nishibori, Li Fu, Hidenori Wake, Dengli Wang, Kiyoshi Teshigawara, Keyue Liu, Hideo K Takahashi, Shuji Mori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective effects of histidine-rich glycoprotein (HRG) on human vascular endothelial cells2017
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Histidine-rich glycoprotein (HRG)の好中球制御による敗血症治療薬の可能性2017
- Author(s)
  和氣秀徳、高遠、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症病態におけるNETsと免疫血栓形成に対する高ヒスチジン糖タンパク質の役割2017
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 抗HMGB1抗体による脳内出血の治療2017
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The role of histidine-rich glycoprotein on NETosis and immunothrombosis in septic condition2017
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] メトホルミンはHMGB1 に直接結合しその炎症促進作用を抑制する2017
- Author(s)
  坂田菜摘、堀内崇弘、鳴海善洋、木村朋寛、林隆史、長野圭介、劉克約、西堀正洋、突田壮平、山田哲也、片桐秀樹、白川龍太郎、堀内久徳
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 赤血球のPSエクスプレション、吸着と疑集におけるHistidine rich-glycoprotein の調節機構2017
- Author(s)
  衷輝、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 抗HMGB1モノクローナル抗体によるピロカルピン誘導性癲癇マウスの病態改善効果の検討2017
- Author(s)
  富麗、劉克約、和氣秀徳、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective effects of histidine-rich glycoprotein (HRG) on vascular endothelial cells2017
- Author(s)
  高尚澤、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Protective effects of histidine-rich glycoprotein on barrier function of vascular endothelial cells.2017
- Author(s)
  Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M.
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] EFFECTS OF INTER-ALPHA INHIBITOR PROTEINS (IAIP) ON THE SHAPE AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN PURIFIED HUMAN NEUTROPHILS2017
- Author(s)
  Soe Soe Htwe、Hidenori Wake、Keyue Liu、Kiyoshi Teshigawara、Yow Pin Lim、Masahiro Nishibori
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 神経障害性疼痛モデルマウスにおけるうつ様行動とHMGB1発現解析2017
- Author(s)
  富村昌暉、中島一恵、吉井稔紀、張　芳芳、劉　克約、西堀正洋、仲田義啓、森岡徳光
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] EFFECTS OF INTER-ALPHA INHIBITOR PROTEINS (IAIP) ON THE SHAPE AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN PURIFIED HUMAN NEUTROPHILS2017
- Author(s)
  Soe Soe Htwe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Yow Pin Lim, Masahiro Nishibori
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 therapy for intracerebral hemorrhage2017
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Histidine rich-glycoprotein regulates erythrocyte PS expression adherent and aggregation2017
- Author(s)
  衷輝、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 脊椎HMGB1関連受容体/グリア細胞/NOSシグナルを介する脳卒中後疼痛の発現機序の解明2017
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 脳卒中後疼痛における脊髄のhigh mobility group box-1/nitiric oxide synthetaseシグナルの関与2017
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 脊髄後角におけるHMGB1 による疼痛惹起メカニズムに対するIL-1βの関与2017
- Author(s)
  宮内一希、張芳芳、中島一恵、劉克約、西堀正洋、仲田義啓、森岡徳光
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Histidine-rich glycoprotein (HRG) の血管内皮細胞保護の効果2017
- Author(s)
  高尚澤、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 抗HMGB1抗体はマウスのピロカルピン誘発痙攣におけるBBB破綻と脳内炎症からマウスを保護する2017
- Author(s)
  西堀正洋、富麗、劉克約、和氣秀徳、高橋英夫、森秀治
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] ヒト血管内皮細胞におけるHistidine rich-glycoprotein (HRG) の保護効果2017
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Role of spinal high mobility group box-1 associated receptors in the induction of central post-stroke pain and the involvement of glia cells in this mechanism2017
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 脳卒中後疼痛に対する脊髄HMGB1関連受容体シグナルおよびグリア細胞の関与2017
- Author(s)
  松浦歩、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein（HRG）の保護効果2016
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 破骨細胞分化過程に対して非炎症分子SHILsが及ぼす影響2016
- Author(s)
  豊村隆男、渡邉政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] AGEs親和性因子としての60S ribosomal proteinの単離2016
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] ピロカルピン誘導性てんかんモデルマウスにおける抗HMGB1抗体の炎症抑制効果2016
- Author(s)
  富麗、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 敗血症時好中球微小循環イメージング2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein (HRG) の保護効果2016
- Author(s)
  高　遠、和氣　秀徳、劉　克約、勅使川原　匡、森　秀治、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Endotoxemia併発急性膵炎に対するHistidine-rich gloycoprotein(HRG)の動態及び治療効果2016
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、高橋英夫、森秀治、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] AGEsによるTNF関連分子の機能変化2016
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Histidine rich glycoproteinの敗血症時好中球性微小循環障害に対する影響2016
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 抗HMGB1抗体による脳内出血の治療2016
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] Anti-HMGB1 mAb attenuates cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats.2016
- Author(s)
  勅使川原匡、春間純、菱川朋人、王登莉、劉克約、和氣秀徳、森秀治、髙橋英夫、杉生憲志、伊達勲、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 敗血症時好中球微小循環イメージング2016
- Author(s)
  和氣　秀徳、森　秀治、高橋　英夫、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Damps関連サイトカインの機能に対するAGEsの影響2016
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb attenuates cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats2016
- Author(s)
  勅使川原匡、春間純、菱川朋人、王登莉、劉克約、和氣秀徳、森秀治、高橋英夫、杉生憲志、伊達勲、西堀正洋
- Organizer
  第130会日本薬理学会近畿部会
- Place of Presentation
  京都大学百周年時計台記念館
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 70kD AGEs結合因子によるAGEsシグナリングへの影響2016
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective effects of histidine rich glycoprotein (HRG) on human vascular endothelial cells2016
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] ラット脳内出血モデルにおける2次性炎症反応と抗HMGB1抗体効果2016
- Author(s)
  西堀正洋、王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治
- Organizer
  第37回日本炎症・再生医学会，京都，2016
- Place of Presentation
  京都市勧業館みやこめっせ
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] ストレプトゾトシン誘発糖尿病ラットにおけるAdvanced glycation end-productsの検出2016
- Author(s)
  森岡祐太、和氣秀徳、勅使川原匡、劉克約、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 非炎症分子SHILsはサイトカインとともに破骨細胞分化を調節する2016
- Author(s)
  豊村隆男、渡邊政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The effects of anti-HMGB1 antibody on pilocarpine-induced epilepsy in mice.2015
- Author(s)
  Fu L, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  7th International Symposium DAMPS and HMGB1.
- Place of Presentation
  Germany, Bonn, University Hospital Bonn.
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 高ヒスチジン糖タンパク質（HRG）の敗血症性immunothrombosis形成に対する影響2015
- Author(s)
  和氣　秀徳、森　秀治、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症病態における微小循環障害に対する高ヒスチジン糖タンパク質の役割2015
- Author(s)
  和氣　秀徳、森　秀治、高橋　英夫、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Tissue factor(TF)誘発DICモデルにおけるHistidine-rich glycoprotein(HRG)の動態及び治療効果について2015
- Author(s)
  寺尾欣也､和氣秀徳､森岡祐太､勅使河原匡､劉克約､髙橋英夫､森秀治、西堀正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K08253
[Presentation] 敗血症病態における高ヒスチジン糖タンパク質（HRG）の好中球形態と微小循環に対する影響2015
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  岐阜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015
- Author(s)
  寺尾　欣也、和氣　秀徳、森岡　祐太、勅使川原　匡、劉　克約、高橋　英夫、森　秀治、西堀　正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  岐阜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 敗血症病態における高ヒスチジン糖タンパク質（HRG）の好中球形態と微小循環に対する影響2015
- Author(s)
  和氣　秀徳、森　秀治、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Anti-HMGB1 therapy for intracerebral hemorrhage.2015
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  7th International Symposium DAMPS and HMGB1.
- Place of Presentation
  Germany, Bonn, University Hospital Bonn.
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] Receptor for advanced glycation end product と肺障害2014
- Author(s)
  出石恭久、和氣秀徳、劉克約、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] AGEs結合親和性に基づいたAGEs遮断ペプチドの同定2014
- Author(s)
  横山隆太、豊村隆男、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] マウス腹膜擦過性肥厚のヒスタミンH1作用による抑制2014
- Author(s)
  足立尚登、劉克約、西堀正洋
- Organizer
  第18回日本ヒスタミン学会，神戸，2014
- Place of Presentation
  都ホテルニューアルカイック
- Year and Date
  2014-10-10
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] AGEs結合親和性に基づいたAGEs遮断ペプチドの同定2014
- Author(s)
  横山隆太、豊村隆男、和氣秀徳、勅使川原匡、劉克約、髙橋英夫、西堀正洋、森秀治
- Organizer
  第125回日本薬理学会近畿部会，岡山，2014
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] Endotoxin血症併発急性膵炎に対するHistidine Rich Grycoprotein (HRG) の効果2014
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、森秀治、髙橋英夫、西堀正洋
- Organizer
  第125回日本薬理学会近畿部会，岡山，2014
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] コラゲナーゼ誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Endotoxin血症併発急性膵炎に対するHistidine Rich Grycoprotein（HRG）の効果2014
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、森秀治、高橋英夫、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2014-03-20
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登利、和氣秀徳、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 循環好中球制御不全による敗血症性ARDSとHRG補充効果2014
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第126回日本薬理学会近畿部会，和歌山，2014
- Place of Presentation
  和歌山県JAビル
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 高ヒスチジン糖タンパク（HRG）による敗血症治療の可能性2014
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 炎症誘発因子HMGB1とインスリン抵抗性の関係についての検討2014
- Author(s)
  衷輝、勅使川原匡、和氣秀徳、劉克約、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 高ヒスチジン糖タンパク質の好中球走化性に対する影響2013
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody.2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S.
- Organizer
  Signalling in the Blood-Brain Barriers.
- Place of Presentation
  Hotel Kapitany, Sumeg, Hungary.
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
- Organizer
  Merinoff World Congress 2013：HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitány,Sümeg, Hungary
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果2013
- Author(s)
  劉克約, 他
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Glycyrrhizin therapy for traumatic brain injury.2013
- Author(s)
  Okuma Y, Liu K, Wake H, Teshigawara K, Haruma J, Date I, Nishibori M.
- Organizer
  Shanghai BRAIN 2013.
- Place of Presentation
  Shanghai International Convention Center, Shanghai, China.
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitany, Sumeg, Hungary
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
- Organizer
  Merinoff World Congress 2013 : HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果2013
- Author(s)
  劉克約、富麗、和氣秀徳、勅使川原匡、西堀正洋
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1 単クローン抗体の効果2013
- Author(s)
  劉克約
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Glycyrrhizin therapy for traumatic brain injury2013
- Author(s)
  Ryu katsuyaku
- Organizer
  Shanghai BRAIN 2013
- Place of Presentation
  Shanghai International Convention Center, CHINA
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] ラットリンパ節細胞を用いた抗AGEモノクローナル抗体の作製2012
- Author(s)
  森岡祐太，友野靖子，和氣秀徳，劉克約，勅使川原匡，高橋英夫，森秀治，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 虚血時脳神経細胞内HMGB1は、核からペルオキシソーム/ミトコンドリアに移動する2012
- Author(s)
  福安悠介，劉克約，和氣秀徳，西村義人，勅使川原匡，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012
- Author(s)
  Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Tomura S, Otani N, Shima K, Yamamoto Y, Yamamoto H, Takahashi H, Mori S, Date I, Nishibori M
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans Morial Convention Center, New Orleans, USA
- Year and Date
  2012-10-16
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] マクロファージによるAdvanced glycation end product　(AGE)の細胞内取り込み2012
- Author(s)
  (13)周京秀，渋谷恵，和氣秀徳，劉克約，森岡祐太，岡村舞，森秀治，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012
- Author(s)
  和氣秀徳，森秀治，高橋英夫，劉克約，勅使川原匡，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 虚血時のBBB透過性亢進を濾出したEvans blue/Albuminの追跡検討2012
- Author(s)
  劉克約，張継勇,和氣秀徳，勅使川原匡，高橋英夫，森秀治，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Tracking the Leakage of Albumin in BBB-disrupted ischemia2012
- Author(s)
  劉克約
- Organizer
  第85回薬理学年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 頭部外傷モデルを用いた抗HMDB1抗体の神経保護効果の検討2012
- Author(s)
  大熊佑、劉克約、和氣秀徳、勅使川原匡、高橋英夫、森秀治、伊達勲、西堀正洋
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  あわぎんホール(徳島)
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011
- Author(s)
  和氣秀徳、森秀治、劉克約、高橋英夫、西堀正洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Early translocation and release of HMGB1 in ischemic brain in rats2011
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Protective effect of anti-HMGB1 antibody on the increase in BBB permeability in rat MCAO model2011
- Author(s)
  劉克約
- Organizer
  第84回日本薬理学会
- Place of Presentation
  パシフィコ横浜会議センター
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 脳虚血早期におけるHMGB1の動態2011
- Author(s)
  劉克約, 他
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 脳虚血早期におけるHMGB1の動態2011
- Author(s)
  劉克約, 西堀正洋, 他4名
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  神奈川,パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 抗HMGB1単クローン抗体はラット脳虚血による血液-脳関門の破錠を制御する2011
- Author(s)
  西堀正洋, 張継勇, 劉克約,和氣秀徳, 高橋英夫, 森秀治,大塚愛二
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011
- Author(s)
  和氣秀徳, 森秀治, 劉克約，高橋英夫, 西堀正洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗HMGB1抗体は脳虚血誘発性の血液-脳関門破綻を防ぐ2011
- Author(s)
  劉克約
- Organizer
  第119回薬理学会近畿部会
- Place of Presentation
  名古屋ウィンク愛知
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 抗HMGB1抗体は脳虚血誘発性の血液-脳関門破綻を防ぐ2011
- Author(s)
  劉克約, 他
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  愛知県産業労働センター
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] Early translocation and release of HMGB1 in ischemic brain in rats2011
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] 抗HMGB1抗体は脳虚血誘発性の血液-脳関門破綻を防ぐ2011
- Author(s)
  劉克約，張継勇, 和氣秀徳, 大塚愛二，森秀治, 高橋英夫,西堀正洋
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] .HMGB1単クローン抗体によるラットMCAO誘発脳梗塞の治療2011
- Author(s)
  西堀正洋、劉克約、張継勇, 和氣秀徳, 大塚愛二，吉野正，伊達勲，高橋英夫, 森秀治
- Organizer
  第47回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] ラット中大脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の効果 : 脳血管透過性亢進に対する影響2010
- Author(s)
  劉克約
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] ヒスチジンとジフェンヒドラミン併用による脳梗塞縮小効果2010
- Author(s)
  劉克約, 他
- Organizer
  第14回日本ヒスタミン学会
- Place of Presentation
  神奈川川崎グランドホテル
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] Disruption of BBB in rat MCAO and a protective effect of anti-HMGB1 antibody2010
- Author(s)
  Liu K, Nishibori M
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Bella Center Copenhagen, Denmark
- Year and Date
  2010-07-19
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Anti-high mobility group box1 monoclonal antibody protects blood-brain barrier from ischemic insult in rat2010
- Author(s)
  Liu K
- Organizer
  14^<th> International Congress Of Immunology
- Place of Presentation
  Kobe International Exhibition Hall
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Anti-high mobility group boxl monoclonal antibody protects blood-brain barrier from ischemic insult in rats2010
- Author(s)
  劉克約
- Organizer
  国際免疫学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] Disruption of BBB in rat MCAO and a protective effect of anti-HMGB1 antibody2010
- Author(s)
  劉克約
- Organizer
  国際薬理学会
- Place of Presentation
  コペンハーゲン
- Year and Date
  2010-07-19
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 脳虚血早期におけるHMGB1の動態2010
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Anti-high mobility group box1 monoclonal antibody protects blood-brain barrier from ischemic insult in rat2010
- Author(s)
  劉克約, 他
- Organizer
  14th International Congress Of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 移植術後糖尿病に対するヒスタミンの効果の基礎検討2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第14回日本ヒスタミン学会
- Place of Presentation
  川崎グランドホテル
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] ラット中大脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の効果:脳血管透過性亢進に対する影響2010
- Author(s)
  劉克約, 西堀正洋, 他6名
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Disruption of BBB in rat MCAO and a protective effect of anti-HMGB1 antibody2010
- Author(s)
  劉克約, 他
- Organizer
  16th World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Bella Center Copenhagen, Denmark
- Year and Date
  2010-07-19
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] Histamine inhibits advanced glycation end product-induced adhesion molecule expression on monocytes during human mixed lymphocyte reaction.2010
- Author(s)
  張継勇, 高橋英夫, 劉克約, 和氣秀徳, 劉瑞, 森秀治, 西堀正洋
- Organizer
  第117回日本薬理学会近畿部会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] Histamine inhibits advanced glycation end product-induced adhesion molecule expression on monocytes during human mixed lymphocyte reaction.2010
- Author(s)
  張継勇, 高橋英夫, 劉克約, 和氣秀徳, 劉瑞, 森秀治, 西堀正洋
- Organizer
  第117回日本薬理学会近畿部会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] ラット中大脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の効果:脳血管透過性亢進に対する影響2010
- Author(s)
  劉克約, 他
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21590594
[Presentation] 移植術後糖尿病に対するヒスタミンの効果の基礎検討2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第14回日本ヒスタミン学会
- Place of Presentation
  川崎グランドホテル
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 脳虚血早期におけるHMGB1の動態2010
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] ラット中脳動脈閉塞・再灌流モデルにおけるBBBと抗HMGB1抗体の効果2009
- Author(s)
  劉克約(他)
- Organizer
  第81日本回薬理学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラット中大脳動脈閉塞・再濯流モデルにおけるBBB破綻と抗HMGBl抗体の効果2009
- Author(s)
  劉克約
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラット中脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の治療効果2008
- Author(s)
  劉克約(他)
- Organizer
  第80回薬理学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラット中脳動脈閉塞・再灌流モデルにおけるBBB破綻と抗HMGB1単クローン抗体の治療効果2008
- Author(s)
  劉克約(他)
- Organizer
  第113回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラット中脳動脈閉塞・再還流モデルにおける抗HMGB1単コローン抗体の治療効果2008
- Author(s)
  劉克約, 他
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラット中大脳動脈閉塞・再還流モデルにおけるBBBの破錠と抗HMGB1単クローン抗体の治療効果2008
- Author(s)
  劉克約
- Organizer
  第113回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラットリンパ節法によるALE特異モノクローナル抗体の作製
- Author(s)
  森岡祐太、大西香織、友野靖子、森秀治、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 破骨細胞様細胞の分化培養における非炎症性物質の影響
- Author(s)
  豊村隆男、和氣秀徳、勅使川原匡、劉克約、髙橋英夫、西堀正洋、森秀治
- Organizer
  第87回日本生化学会大会，京都，2014
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 好中球活性化制御に着目した敗血症病態解析と治療法開発
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第87回日本生化学会大会，京都，2014
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation.
- Author(s)
  Masahiro Nishibori, Hidenori Wake, Shuji Mori, Keyue Liu, Yuta Morioka, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Kosuke Kuroda, Hideo Takahashi, Aiji Ohtsuka, Tadashi Yoshino, Hiroshi Morimatsu
- Organizer
  Sepsis Symposium
- Place of Presentation
  France, Paris, Pasteur Institute
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 破骨細胞様細胞の分化培養における非炎症性物質の影響
- Author(s)
  豊村隆男、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 好中球活性化制御に着目した敗血症病態解析と治療法開発
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ピロカルピン誘発性てんかんモデルマウスにおける抗HMGB-1抗体の効果
- Author(s)
  富麗、劉克約、和氣秀徳、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] グリチルリチンはHMGB1に結合し脳外傷を抑制する
- Author(s)
  春間純、大熊佑、劉克約、和氣秀徳、衷輝、勅使川原匡、伊達勲、西堀正洋
- Organizer
  第１２３回日本薬理学会近畿部会
- Place of Presentation
  ウインク愛知
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果
- Author(s)
  劉　克約　他
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 頭部外傷モデルを用いたGlycyrrhizinの神経保護効果の検討
- Author(s)
  大熊佑、劉克約、春間純、高橋英夫、森秀治、西野繁樹、西堀正洋、伊達勲
- Organizer
  日本脳神経外科学会第72回学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果
- Author(s)
  劉　克約
- Organizer
  第８６回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] マクロファージによるadvanced glycation end products (AGEs)の細胞内取り込み
- Author(s)
  高遠、森岡祐太、森秀治、和氣秀徳、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会，名古屋，2015
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] DAMPとしてのHMGB1：脳外傷と肺障害
- Author(s)
  大熊佑、劉克約、春間純、高橋英夫、森秀治、西野繁樹、伊達勲、西堀正洋
- Organizer
  第24回日本急性血液浄化学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 高ヒスチジン糖タンパク質（HRG）の敗血症時血管内好中球流動性に対する効果
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats.
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S.
- Organizer
  Merinoff World Congress 2013：HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA.
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 抗HMGB1抗体による脳内出血とクモ膜下出血後の脳血管攣縮治療
- Author(s)
  王登莉、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会　シンポジウム，名古屋2015
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析
- Author(s)
  森秀治、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Antibody Therapy for Brain Ischemia, Brain Injury and Neuropathic Pain.
- Author(s)
  Nishibori M, Liu K, Takahashi HK, Mori S.
- Organizer
  International Drug Development Science & Technology 2014
- Place of Presentation
  Tongli Lakeview Hotel, Suzhou, China.
- Year and Date
  2014-11-18 – 2014-11-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] マクロファージによるAdvanced glycation end productsの細胞内取り込み
- Author(s)
  森岡祐太、周京秀、渋谷恵、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果
- Author(s)
  劉　克約　他
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] グリチルリチンはHMGB1に結合し脳外傷を抑制する
- Author(s)
  春間純、大熊佑、劉克約、和氣秀徳、衷輝、勅使川原匡、伊達勲、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ピロカルピン誘発性てんかんモデルマウスにおける抗HMGB-1抗体の効果
- Author(s)
  富麗、劉克約、和氣秀徳、西堀正洋
- Organizer
  第88回日本薬理学会年会，名古屋，2015
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] ラットリンパ節法によるALE特異モノクローナル抗体の作製
- Author(s)
  森岡祐太、大西香織、友野靖子、森秀治、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析
- Author(s)
  森秀治、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析
- Author(s)
  森秀治、和氣秀徳、劉克約、勅使川原匡、髙橋英夫、西堀正洋、豊村隆男
- Organizer
  第87回日本生化学会大会，京都，2014
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] マクロファージによるadvanced glycation end products (AGEs)の細胞内取り込み
- Author(s)
  高遠、森岡祐太、森秀治、和氣秀徳、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Antibody Therapy for Brain Ischemia, Brain Injury and Neuropathic Pain
- Author(s)
  Nishibori M, Liu K, Takahashi HK, Mori S.
- Organizer
  International Drug Development Science & Technology
- Place of Presentation
  Tongli Lakeview Hotel, Suzhou, China
- Year and Date
  2014-11-18 – 2014-11-20
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 抗HMGB1抗体による脳内出血とクモ膜下出血後の脳血管攣縮治療
- Author(s)
  王登莉、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation
- Author(s)
  Nishibori M, Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakagichi M, Kuroda K, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H
- Organizer
  SEPSIS 2014
- Place of Presentation
  Institut Pasteur, Paris, France
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-24590658

1. NISHIBORI Masahiro (50135943)

# of Collaborated Projects: 16 results

# of Collaborated Products: 248 results
2. TAKAHASHI Hideo (60335627)

# of Collaborated Projects: 10 results

# of Collaborated Products: 95 results
3. WAKE Hidenori (60570520)

# of Collaborated Projects: 9 results

# of Collaborated Products: 171 results
4. TESHIGAWARA Kiyoshi (40403737)

# of Collaborated Projects: 5 results

# of Collaborated Products: 118 results
5. NIWA Atsuko (60122082)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. MORI Shuji (50220009)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
7. DATE Isao (70236785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. TERADA SEISHI (20332794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 菅家徹 (50432638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中村恭子 (10512197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大島佳奈 (60278653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小堀宅郎 (60734697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 白井敦 (20302226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 王登莉 (40815693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
15. OKUMA Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. MATSUNAMI Maho

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. SADAMORI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. KAMEDA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. HISHIKAWA Tomohito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 豊村隆男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 渡邊政博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 関口富美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 川畑篤史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 木村朋寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 杉生憲司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 徳永浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 市川智継

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

RYU Katsuyaku 劉 克約

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Therapeutic Potential of an Anti-High Mobility Group Box1 Monoclonal Antibody in Hemorrhagic strokePrincipal Investigator

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Development of monoclonal antibodies therapy for cerebral infarction and cerebral edema in primate animal modePrincipal Investigator

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Development of monoclonal antibodies therapy for cerebral infarction and cerebral edemaPrincipal Investigator

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Development of antibody therapy for brain infarctionPrincipal Investigator

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RYU Katsuyaku 劉克約