Kitada Munehiro 北田宗弘

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KITADA Munehiro 北田宗弘

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Researcher Number	40434469
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 和歌山県立医科大学, 医学部, 博士研究員 2014 – 2023: 金沢医科大学, 医学部, 准教授 2012 – 2013: 金沢医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 58060:Clinical nursing-related / Kidney internal medicine / Eating habits
Keywords	Principal Investigator オートファジー / 糖尿病性腎臓病 / 糖尿病性腎症 / 炎症 / 糖尿病腎症 / 慢性腎臓病 / システイニルロイコトリエン受容体1 / 腎尿細管間質 / 尿細管間質障害 / プランルカスト … More / システイニルロイコトリエン受容体1 / 糖尿病関連腎臓病 / 糖尿病 / mTOR1 / グリシンNメチルトランスフェラーゼ / S-アデノシルメチオニン / メチオニン / 低蛋白質食 / 2型糖尿病ラット / たんぱく質制限食 / サーチュイン / 栄養応答シグナル / ｵｰﾄﾌｧｼﾞｰ / 尿細管 / ミトコンドリア / たんぱく質制限 / mTOR / 低たんぱく質食 … More Except Principal Investigator 糖尿病 / カロリー制限 / オートファジー / DAG / MGAT / SGLT-２阻害薬 / 糖尿病性腎臓病 / HK細胞 / MAPK / シングルセル解析 / MGAT2 / PKC / 高齢糖尿病患者 / 医療の標準化 / 疾病負荷 / 安全性 / 自立支援 / 家族 / 自己管理 / 慢性腎臓病 / 高齢者 / EQ-5D-5L / 新型コロナウイルス感染症 / 認知症 / 医療依存度 / 糖尿病ディストレス / QOL / 医療経済 / 介護 / 自己管理能力 / 併存疾患 / 重症化予防 / 糖尿病重症化予防 / 認知機能 / 加齢変化 / 橋渡し研究 / 動機づけ面接 / 生活習慣改善 / アクセプタビリティ / 糖尿病自己管理 / 糖尿病発症・重症化予防 / 老年症候群 / 高齢者糖尿病 / ﾐﾄｺﾝﾄﾞﾘｱ / サーチュイン / CD38 / 酸化ストレス / ミトコンドリア / Sirt3 / 糖尿病腎症 / SIRT1 / mTOR / 代謝 / 骨格筋 / ケト原性アミノ酸 / 線維化 / ポドサイト / 腎障害 / 代謝異常 / メチオニン / たんぱく質 / ケイ原性アミノ酸 / たんぱく質制限 Less

Elucidation of the mechanism of cyclic and intermittent very low-protein diet on chronic kidney disease that has high risk of its progressionPrincipal Investigator
- Principal Investigator
  
  北田宗弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Wakayama Medical University
Elucidation of the role of cysteinyl leukotriene receptor1 on advanced diabetic kidney diseasePrincipal Investigator
- Principal Investigator
  
  Munehiro Kitada
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Wakayama Medical University
  Kanazawa Medical University
New therapeutic strategy for diabetic kidney disease by inhibiting MGAT
- Principal Investigator
  
  古家大祐
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kanazawa Medical University
Translational research for ensuring acceptability of lifestyle management of older people with diabetes
- Principal Investigator
  
  Morikawa Hiroko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Kyoto University
  Komatsu University
Elucidation of role of changing S-adenosylmethionine (SAM) metabolism for the pathogenesis of diabetic kidney diseasePrincipal Investigator
- Principal Investigator
  
  KITADA Munehiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa Medical University
The role of Sirtuin on diabetic nephropatfunctionhy based on maintaining mitochondrial
- Principal Investigator
  
  WATANABE Ai
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa Medical University
Alteration in nutrient sensing and metabolic diseases
- Principal Investigator
  
  KOYA Daisuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
Elucidation of mechanism by which low protein diet suppresses progression of diabetic nephropathy through activation of autophagy in tubular cellsPrincipal Investigator
- Principal Investigator
  
  KITADA Munehiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa Medical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation Book

[Book] 特集糖尿病の食事療法を極める　蛋白質の摂取量と糖尿病の管理―糖尿病性腎症における低蛋白質食を考える―2019
- Author(s)
  北田宗弘
- Total Pages
  6
- Publisher
  月刊糖尿病
- Data Source
  KAKENHI-PROJECT-17K09718
[Book] 特集健康長寿を目指した食事療法の設定根拠とその実際　糖尿病性腎症患者の食事療法―低蛋白質食を中心に―2019
- Author(s)
  北田宗弘
- Total Pages
  5
- Publisher
  内分泌・糖尿病・代謝内科
- Data Source
  KAKENHI-PROJECT-17K09718
[Journal Article] 糖尿病性腎臓病に対する包括的治療のポイント2023
- Author(s)
  北田宗弘
- Journal Title
  
  Journal of Clinical Rehabilitation
  
  Volume: 32(10) Pages: 980-986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] The Role of CD38 in the Pathogenesis of Cardiorenal Metabolic Disease and Aging, an Approach from Basic Research2023
- Author(s)
  Kitada Munehiro、Araki Shin-ichi、Koya Daisuke
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 4 Pages: 595-595
- DOI
  10.3390/cells12040595
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290
[Journal Article] Adenosine/adenosine type?1 receptor signaling pathway did not play dominant roles on the influence of sodium?glucose cotransporter?2 inhibitor in the kidney of bovine serum albumin‐overloaded streptozotocin‐induced diabetic mice2022
- Author(s)
  Shimada Keiji、Kanasaki Keizo、Kato Makoto、Ogura Yoshio、Takagaki Yuta、Monno Itaru、Hirai Taro、Kitada Munehiro、Koya Daisuke
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: Online ahead of print Issue: 6 Pages: 955-964
- DOI
  10.1111/jdi.13760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773, KAKENHI-PROJECT-22K08330
[Journal Article] 糖尿病性腎臓病の食事療法～摂取タンパク質量の制限からタンパク源を重視した食事パターンへ～2022
- Author(s)
  北田宗弘
- Journal Title
  
  糖尿病合併症
  
  Volume: 36 Pages: 234-238
- Data Source
  KAKENHI-PROJECT-21K08290
[Journal Article] Rationale, design and baseline characteristics of the effect of canagliflozin in patients with type 2 diabetes and microalbuminuria in the Japanese population: The CANPIONE study2022
- Author(s)
  Miyamoto S, Heerspink HJL, de Zeeuw D, Toyoda M, Suzuki D, Hatanaka T, Nakamura T, Kamei S, Murao S, Hida K, Ando S, Akai H, Takahashi Y, Koya D, Kitada M, Sugano H, Nunoue T, Nakamura A, Sasaki M, Nakatou T, Fujimoto K, Kawanami D, Wada T, Miyatake N, Yoshida M, Shikata K; CANPIONE study Investigators.
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 24 Issue: 8 Pages: 1429-1438
- DOI
  10.1111/dom.14731
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] 糖尿病性腎臓病を視野に入れた糖尿病治療薬の選択2022
- Author(s)
  北田宗弘・古家大祐
- Journal Title
  
  腎臓内科
  
  Volume: 15 Pages: 55-63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] Effects of SGLT2 Inhibitors on Atherosclerosis: Lessons from Cardiovascular Clinical Outcomes in Type 2 Diabetic Patients and Basic Researches2021
- Author(s)
  Xu J, Hirai T, Koya D, Kitada M.
- Journal Title
  
  J Clin Med.
  
  Volume: 11 Issue: 1 Pages: 137-137
- DOI
  10.3390/jcm11010137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] NAD+ Homeostasis in Diabetic Kidney Disease.2021
- Author(s)
  Xu J, Kitada M, Koya D.
- Journal Title
  
  Front Med (Lausanne).
  
  Volume: 8 Pages: 703076-703076
- DOI
  10.3389/fmed.2021.703076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] Relationship Between Autophagy and Metabolic Syndrome Characteristics in the Pathogenesis of Atherosclerosis2021
- Author(s)
  Xu J, Kitada M, Ogura Y, Koya D.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 9 Pages: 641852-641852
- DOI
  10.3389/fcell.2021.641852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] 糖尿病性腎症（DKD)の治療　食事療法（保存期）2021
- Author(s)
  北田宗弘・古家大祐
- Journal Title
  
  腎と透析
  
  Volume: 91 Pages: 638-642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] Exercise Ameliorates Diabetic Kidney Disease in Type 2 Diabetic Fatty Rats.2021
- Author(s)
  Monno I, Ogura Y, Xu J, Koya D, Kitada M.
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 11 Pages: 1754-1754
- DOI
  10.3390/antiox10111754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys.2021
- Author(s)
  Srivastava SP, Li J, Takagaki Y, Kitada M, Goodwin JE, Kanasaki K, Koya D.
- Journal Title
  
  iScience
  
  Volume: - Issue: 5 Pages: 102390-102390
- DOI
  10.1016/j.isci.2021.102390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Autophagy in metabolic disease and ageing.2021
- Author(s)
  Kitada M, Koya D.
- Journal Title
  
  Nat Rev Endocrinol.
  
  Volume: 11 Issue: 11 Pages: 647-461
- DOI
  10.1038/s41574-021-00551-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] Dapagliflozin Restores Impaired Autophagy and Suppresses Inflammation in High Glucose-Treated HK-2 Cells2021
- Author(s)
  Xu J, Kitada M, Ogura Y, Liu H, Koya D.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 6 Pages: 1457-1457
- DOI
  10.3390/cells10061457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] 糖尿病から腎臓を守る”くすり”の話2021
- Author(s)
  北田宗弘・古家大祐
- Journal Title
  
  さかえ：月刊糖尿病ライフ
  
  Volume: 61 Pages: 5-10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] 糖尿病性腎臓病に対する内因性保護的因子としてのオーとファジーの役割2021
- Author(s)
  北田宗弘、古家大祐
- Journal Title
  
  医学のあゆみ
  
  Volume: 276 Pages: 468-473
- Open Access
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] Sodium-glucose cotransporter 2 inhibitors in type 2 diabetes patients with renal function impairment slow the annual renal function decline, in a real clinical practice2021
- Author(s)
  Hirai T, Kitada M, Monno I, Oda E, Hayashi Y, Shimada K, Takagaki Y, Ogura Y, Fujii M, Konishi K, Sakurai M, Nakagawa A, Koya D.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 12 Issue: 9 Pages: 1577-1585
- DOI
  10.1111/jdi.13502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Effect of Methionine Restriction on Aging: Its Relationship to Oxidative Stress.2021
- Author(s)
  Kitada M, Ogura Y, Monno I, Xu J, Koya D.
- Journal Title
  
  Biomedicines.
  
  Volume: - Issue: 2 Pages: 130-130
- DOI
  10.3390/biomedicines9020130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Sirtuins and Renal Oxidative Stress.2021
- Author(s)
  Ogura Y, Kitada M, Koya D.
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 8 Pages: 1198-1198
- DOI
  10.3390/antiox10081198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08290, KAKENHI-PROJECT-20K21773
[Journal Article] Medical nutrition therapy and dietary counseling for patients with diabetes-energy, carbohydrates, protein intake and dietary counseling2020
- Author(s)
  Yamauchi Toshimasa、Kamiya Hideki、Utsunomiya Kazunori、Watada Hirotaka、Kawanami Daiji、Sato Junko、Kitada Munehiro、Koya Daisuke、Harada Norio、Shide Kenichiro、Joo Erina、Suzuki Ryo、Bouchi Ryotaro、Ohta Yasuharu、Kondo Tatsuya
- Journal Title
  
  Diabetology International
  
  Volume: 11 Issue: 3 Pages: 224-239
- DOI
  10.1007/s13340-020-00437-7
- NAID
  130007821841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08714, KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-20K21773
[Journal Article] CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD +/NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats2020
- Author(s)
  Ogura Y, Kitada M, Xu J, Monno I, Koya D.
- Journal Title
  
  Aging (Albany NY) .
  
  Volume: 12 Issue: 12 Pages: 11325-11336
- DOI
  10.18632/aging.103410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease2020
- Author(s)
  Kitada M, Xu J, Ogura Y, Monno I, Koya D.
- Journal Title
  
  Front Physiol .
  
  Volume: 11 Pages: 755-755
- DOI
  10.3389/fphys.2020.00755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] 糖尿病性腎臓病に対するSGLT2阻害薬の臨床的重要性2020
- Author(s)
  北田宗弘、古家大祐
- Journal Title
  
  Progress in Medicine
  
  Volume: 40 Pages: 117-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity2020
- Author(s)
  Watanabe E, Wada T, Okekawa A, Kitamura F, Komatsu G, Onogi Y, Yamamoto S, Sasahara M, Kitada M, Koya D, Tsuneki H, Sasaoka T.
- Journal Title
  
  Angiogenesis .
  
  Volume: 23 Issue: 4 Pages: 667-684
- DOI
  10.1007/s10456-020-09738-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-18K08469
[Journal Article] 「糖尿病ガイドライン2019」改訂のポイント、糖尿病性腎症の食事療法　糖尿病性腎症重症化予防に向けて2020
- Author(s)
  北田宗弘、古家大祐
- Journal Title
  
  臨床栄養
  
  Volume: 136 Pages: 460-464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules2020
- Author(s)
  Li J, Liu H, Takagi S, Nitta K, Kitada M, Srivastava SP, Kanasaki K et al.
- Journal Title
  
  JCI Insight.
  
  Volume: 5 Issue: 6 Pages: 6-6
- DOI
  10.1172/jci.insight.129034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling2020
- Author(s)
  Kawakita Emi、Yang Fan、Kumagai Asako、Takagaki Yuta、Kitada Munehiro、Yoshitomi Yasuo、Ikeda Takayuki、Nakamura Yuka、Ishigaki Yasuhito、Kanasaki Keizo、Koya Daisuke
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 19 Issue: 1 Pages: 61-73
- DOI
  10.1158/1541-7786.mcr-20-0115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07407, KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-21K09031, KAKENHI-PROJECT-20K21773
[Journal Article] The impact of mitochondrial quality control by Sirtuins on the treatment of type 2 diabetes and diabetic kidney disease2020
- Author(s)
  Xu J, Kitada M, Koya D.
- Journal Title
  
  Biochim Biophys Acta Mol Basis Dis
  
  Volume: 1866 Issue: 6 Pages: 165756-165756
- DOI
  10.1016/j.bbadis.2020.165756
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis.2020
- Author(s)
  Takagaki Y, Lee SM, Dongqing Z, Kitada M, Kanasaki K, Koya D
- Journal Title
  
  Autophagy.
  
  Volume: - Issue: 10 Pages: 1-10
- DOI
  10.1080/15548627.2020.1713641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Supplementation with Red Wine Extract Increases Insulin Sensitivity and Peripheral Blood Mononuclear Sirt1 Expression in Nondiabetic Humans2020
- Author(s)
  Kitada M, Ogura Y, Monno I, Koya D.
- Journal Title
  
  Nutrients .
  
  Volume: 12 Issue: 10 Pages: 3108-3108
- DOI
  10.3390/nu12103108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Case report of superior mesenteric artery syndrome that developed in a lean type 2 diabetes patient and was associated with rapid body weight loss after sodium-glucose cotransporter 2 inhibitor administration2020
- Author(s)
  Hirai T, Kitada M, Hayashi Y, Monno I, Takagaki Y, Shimada K, Ogura Y, Fujii M, Konishi K, Nakagawa A, Koya D.
- Journal Title
  
  J Diabetes Investig .
  
  Volume: 11 Issue: 5 Pages: 1359-1362
- DOI
  10.1111/jdi.13228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Endothelial FGFR1 (Fibroblast Growth Factor Receptor 1) Deficiency Contributes Differential Fibrogenic Effects in Kidney and Heart of Diabetic Mice2020
- Author(s)
  Li J, Liu H, Srivastava SP, Hu Q, Gao R, Li S, Kitada M, Wu G, Koya D, Kanasaki K.
- Journal Title
  
  Hypertension .
  
  Volume: 76 Issue: 6 Pages: 1935-1944
- DOI
  10.1161/hypertensionaha.120.15587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Significance of SGLT2 inhibitors: lessons from renal clinical outcomes in patients with type 2 diabetes and basic researches2020
- Author(s)
  Kitada M, Hirai T, Koya D.
- Journal Title
  
  Diabetol Int.
  
  Volume: 11 Issue: 3 Pages: 245-251
- DOI
  10.1007/s13340-020-00444-8
- NAID
  40022307347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Mechanism of Activation of Mechanistic Target of Rapamycin Complex 1 by Methionine2020
- Author(s)
  Kitada M, Xu J, Ogura Y, Monno I, Koya D.
- Journal Title
  
  Front Cell Dev Biol .
  
  Volume: 8 Pages: 715-715
- DOI
  10.3389/fcell.2020.00715
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773
[Journal Article] Methionine Abrogates the Renoprotective Effect of a Low-Protein Diet Against Diabetic Kidney Disease in Obese Rats With Type 2 Diabetes2020
- Author(s)
  Kitada M, Ogura Y, Monno I, Xu J, Koya D.
- Journal Title
  
  Aging (Albany NY)
  
  Volume: 12 Issue: 5 Pages: 4489-4505
- DOI
  10.18632/aging.102902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09718, KAKENHI-PROJECT-20K21773
[Journal Article] CD‐1db/db mice: a novel type 2 diabetic mouse model with progressive kidney fibrosis2020
- Author(s)
  Mizunuma Yuiko、Kanasaki Keizo、Nitta Kyoko、Nakamura Yuka、Ishigaki Yasuhito、Takagaki Yuta、Kitada Munehiro、Li Shaolan、Liu Haijie、Li Jinpeng、Usui Isao、Aso Yoshimasa、Koya Daisuke
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 10.1111/jdi.13311 Issue: 6 Pages: 1-23
- DOI
  10.1111/jdi.13311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18015, KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance through the CXCL12/CXCR4/mTOR/TGFbeta Signaling Pathway in Breast Cancer Cells.2020
- Author(s)
  Li S, Fan Y, Kumagai A, Kawakita E, Kitada M, Kanasaki K, et al.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 3 Pages: 3-3
- DOI
  10.3390/ijms21030805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity2020
- Author(s)
  Onogi Yasuhiro、Wada Tsutomu、Okekawa Akira、Matsuzawa Takatoshi、Watanabe Eri、Ikeda Keisuke、Nakano Minoru、Kitada Munehiro、Koya Daisuke、Tsuneki Hiroshi、Sasaoka Toshiyasu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 670-670
- DOI
  10.1038/s41598-019-57368-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08469, KAKENHI-PROJECT-17H02941, KAKENHI-PROJECT-20K21773
[Journal Article] 合併症や併存症を見据えた最適医療　最新のエビデンスに基づく糖尿病患者の慢性腎臓病の治療戦略2020
- Author(s)
  北田宗弘、古家大祐
- Journal Title
  
  Medical Practice
  
  Volume: 37 Pages: 1741-1746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] 高血糖・低血糖のしくみと治療・ケア　高血糖と慢性合併症の関係2019
- Author(s)
  北田宗弘、古家大祐
- Journal Title
  
  糖尿病ケア
  
  Volume: 16 Pages: 982-985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] The impact of dietary protein intake on longevity and metabolic health.2019
- Author(s)
  Kitada M, Ogura Y, Monno I, Koya D.
- Journal Title
  
  EBioMedicine.
  
  Volume: - Pages: 632-640
- DOI
  10.1016/j.ebiom.2019.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15472, KAKENHI-PROJECT-17K09718
[Journal Article] 蛋白質の摂取量と糖尿病の管理　糖尿病性腎症における低蛋白食を考える2019
- Author(s)
  北田宗弘、古家大祐
- Journal Title
  
  月刊糖尿病
  
  Volume: 11 Pages: 47-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] 日本糖尿病学会と日本腎臓学会の専門医間の紹介規準2019
- Author(s)
  北田宗弘
- Journal Title
  
  プラクティス
  
  Volume: 36 Pages: 754-756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] 「陣と栄養・代謝」肥満と腎臓病2019
- Author(s)
  北田宗弘・古家大祐
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: ９ Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] 医療の標準化とアクセプタビリティリサーチ2019
- Author(s)
  森川浩子・任和子・北田宗弘・古家大祐
- Journal Title
  
  Bio Clinica
  
  Volume: 34 Pages: 106-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] 糖尿病診療の標準化と情報発信2018
- Author(s)
  森川浩子・任和子・北田宗弘・古家大祐
- Journal Title
  
  Bio Clinica
  
  Volume: 33 Pages: 93-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10269
[Journal Article] A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity.2016
- Author(s)
  Kitada M, Ogura Y, Suzuki T, Sen S, Lee SM, Kanasaki K, Kume S, Koya D.
- Journal Title
  
  Diabetologia
  
  Volume: in press Issue: 6 Pages: 1307-17
- DOI
  10.1007/s00125-016-3925-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-26460403
[Journal Article] Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen2016
- Author(s)
  Nitta K, Shi S, Nagai T, Kanasaki M, Kitada M, Srivastava SP, Haneda M, Kanasaki K, Koya D.
- Journal Title
  
  Biomed Res Int
  
  Volume: 2016:9172157 Pages: 9172157-9172157
- DOI
  10.1155/2016/9172157
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028
[Journal Article] Interactions of DPP-4 and integrin β1 influences endothelial-to mesenchymal transition.2015
- Author(s)
  Shi S, Srivastava SP, Kanasaki M, He J, Kitada M, Nagai T, Nitta K, Takagi S, Kanasaki K, Koya D.
- Journal Title
  
  Kidney Int.
  
  Volume: - Issue: 3 Pages: 479-489
- DOI
  10.1038/ki.2015.103
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028
[Journal Article] Role of sirtuins in kidney disease.2014
- Author(s)
  Kitada M, Kume S, Koya D.
- Journal Title
  
  Curr Opin Nephrol Hypertens.
  
  Volume: 23 Issue: 1 Pages: 75-79
- DOI
  10.1097/01.mnh.0000437330.85675.ac
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Journal Article] Clinical therapeutic strategies for early stage of diabetic kidney disease.2014
- Author(s)
  Kitada M, Kanasaki K, Koya D
- Journal Title
  
  World J Diabetes.
  
  Volume: 5 Issue: 3 Pages: 342-356
- DOI
  10.4239/wjd.v5.i3.342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-26460403
[Journal Article] Linagriptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabeticmice by inhibiting endothelial-to mesenchymal transition in a therapeutic regimen.2014
- Author(s)
  Kanasaki K, Shi S, Kanasaki M, He J, Nagai T, Nakamura Y, Ishigaki Y, Kitada M, Srivastava SP, Koya D.
- Journal Title
  
  Diabetes.
  
  Volume: 63 Issue: 6 Pages: 2120-2131
- DOI
  10.2337/db13-1029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-26460403
[Journal Article] SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential.2013
- Author(s)
  Kitada M, Koya D.
- Journal Title
  
  Diabetes Metab J.
  
  Volume: 37(5) Pages: 315-325
- Data Source
  KAKENHI-PROJECT-24591218
[Journal Article] Sirtuins as possible drug targets in type 2 diabetes.2013
- Author(s)
  Kitada M, Kume S, Kanasaki K, Takeda-Watanabe A, Koya D.
- Journal Title
  
  Curr Drug Targets
  
  Volume: 14 Pages: 622-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282028
[Journal Article] Renal protective effects of resveratrol.2013
- Author(s)
  Kitada M, Koya D.
- Journal Title
  
  Oxid Med Cell Longev.
  
  Volume: 2013 Pages: 1-7
- DOI
  10.1155/2013/568093
- NAID
  40019560561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218
[Journal Article] Anti-aging molecule, Sirt1: a novel therapeutic target for diabetic nephropathy2013
- Author(s)
  Kume S.
- Journal Title
  
  Arch Pharm Res.
  
  Volume: 36(2) Issue: 2 Pages: 230-6
- DOI
  10.1007/s12272-013-0019-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-23890085, KAKENHI-PROJECT-24591218
[Journal Article] Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP1c Tg mice fed high-fat and high-fructose diet2013
- Author(s)
  Wada T, Miyashita Y, Sasaki M, Aruga Y, Nakamura Y, Ishii Y, Sasahara M, Kanasaki K, Kitada M, Koya D, Shimano H, Tsuneki H, Sasaoka
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 305 Issue: 11 Pages: E1415-E1425
- DOI
  10.1152/ajpendo.00419.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-24390230, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-25670414
[Journal Article] Sirtuins and renal diseases: relationship with aging and diabetic nephropathy2013
- Author(s)
  Kitada M.
- Journal Title
  
  Clin Sci (Lond)
  
  Volume: 124(3) Issue: 3 Pages: 153-64
- DOI
  10.1042/cs20120190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-23890085, KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25670414
[Journal Article] The use of calorie restriction mimetics to study aging.2013
- Author(s)
  Kitada M, Koya D.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1048 Pages: 95-107
- DOI
  10.1007/978-1-62703-556-9_8
- ISBN
  9781627035552, 9781627035569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25670414
[Journal Article] Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules.2013
- Author(s)
  Xu L, Kanasaki M, He J, Kitada M, Nagao K, Jinzu H, Noguchi Y, Maegawa H, Kanasaki K, Koya D.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1832(10) Issue: 10 Pages: 1605-1612
- DOI
  10.1016/j.bbadis.2013.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Journal Article] irtuins as possible drug targets in type 2 diabetes.2013
- Author(s)
  Kitada M, Kume S, Kanasaki K, Takeda-Watanabe A, Koya D
- Journal Title
  
  Curr Drug Targets.
  
  Volume: 14(6) Pages: 622-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218
[Journal Article] The biological consequence of obesity on the kidney2013
- Author(s)
  Keizo Kanasaki, Munehiro Kitada, Megumi Kanasaki, Daisuke Koya
- Journal Title
  
  Nephrology Dialysis and Transplantation
  
  Volume: Suppl 4 Issue: suppl 4 Pages: iv1-iv7
- DOI
  10.1093/ndt/gft098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-25282028
[Journal Article] SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential.2013
- Author(s)
  Kitada M, Koya D.
- Journal Title
  
  Diabetes Metab J.
  
  Volume: 37 Pages: 315-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282028
[Journal Article] Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation.2013
- Author(s)
  Kitada M, Kume S, Takeda-Watanabe A, Tsuda S, Kanasaki K, Koya D.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1830(10) Issue: 10 Pages: 4820-4827
- DOI
  10.1016/j.bbagen.2013.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Presentation] 糖尿病性腎臓病に対する食事療法の在り方を考える～摂取蛋白質について～2023
- Author(s)
  北田宗弘
- Organizer
  第66回日本糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08290
[Presentation] 糖尿病性腎症に対する食事療法のポイント2023
- Author(s)
  北田宗弘
- Organizer
  第58回　糖尿病学の進歩
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] 運動負荷は２型糖尿病/肥満ラット腎における炎症を軽減する2021
- Author(s)
  門野　至, 小倉慶雄, 北田宗弘, Jing Xu, 古家大祐
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08290
[Presentation] 糖尿病重症化予防のための地域連携協議会による活動と現状および今後の課題2021
- Author(s)
  小西一典・中野茂・北田宗弘・古家大祐
- Organizer
  日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] 体組成計Seca mBCA151を用いた入院当脳病患者における体組成変化に関する検討2021
- Author(s)
  平井太郎・北田宗弘・古家大祐
- Organizer
  日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] 糖尿病性腎臓病を有する2型糖尿病患者に対するＳＧＬＴ2阻害薬の追加灯投与はeGFRの年次低下速度を緩和する2020
- Author(s)
  北田宗弘、古家大祐
- Organizer
  第63回日本糖尿病学会年次集会
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] Renal protective mechanism of SGLT2 inhibitors2020
- Author(s)
  古家大祐、北田宗弘
- Organizer
  第63回日本糖尿病学会年次集会
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] 糖尿病性腎臓病における食事療法を考える　蛋白質の量と質の観点から2020
- Author(s)
  北田宗弘、古家大祐
- Organizer
  第63回日本糖尿病学会年次集会
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] 摂取蛋白質の“量”と“質”の観点から糖尿病性腎臓病に対する食事療法を考える2019
- Author(s)
  北田宗弘、古家大祐
- Organizer
  第34回日本糖尿病合併症学会シンポジウム
- Data Source
  KAKENHI-PROJECT-17K09718
[Presentation] 2型糖尿病/肥満ラットにおける腎尿細管Gnmt低下とメチオニン代謝産物SAMの蓄積は糖尿病性腎臓病の病態形成に関与している2019
- Author(s)
  北田宗弘、小倉慶雄、門野至、古家大祐
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K09718
[Presentation] 炎症性Diet　メタボリックヘルスと寿命延長における摂取蛋白質の量と質の意義2019
- Author(s)
  北田宗弘、古家大祐
- Organizer
  日本坑加齢医学会
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] 糖尿病・循環器ガイドラインに準じた糖尿病食、循環器疾患食・糖質制限食の栄養素量についての分析・評価2019
- Author(s)
  松波俊哉・北田宗弘・古家大祐
- Organizer
  日本病態栄養学会誌
- Data Source
  KAKENHI-PROJECT-18K10269
[Presentation] Sirt3機能低下は糖尿病腎近位尿細管におけるミトコンドリア酸化ストレスの増2017
- Author(s)
  小倉慶雄、北田宗弘、鈴木妙子、門野至、渡邊愛、古家大祐
- Organizer
  第60回日本糖尿病学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-26860651
[Presentation] たんぱく質制限による2型糖尿病腎尿細管におけるﾐﾄｺﾝﾄﾞﾘｱの断片化と融合ﾊﾞﾗﾝｽの是正と腎保護効果2015
- Author(s)
  北田宗弘
- Organizer
  日本腎臓学会年次学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-24591218
[Presentation] たんぱく質制限の2型糖尿病ﾗｯﾄ腎症に対する腎保護効果2015
- Author(s)
  北田宗弘
- Organizer
  日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ他（山口県下関市）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-24591218
[Presentation] ２型糖尿病腎症における高度たんぱく質制限の腎保護効果と糖・脂質代謝への影響2012
- Author(s)
  北田宗弘
- Organizer
  日本腎臓学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24591218

1. KOYA Daisuke (70242980)

# of Collaborated Projects: 7 results

# of Collaborated Products: 57 results
2. KUME Shinji (00452235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KANASAKI Keizo (60589919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. WATANABE Ai (70625722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Morikawa Hiroko (10313743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 任和子 (40243084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 荒木信一 (80378455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中佑典 (00612110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 川浪大治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高垣雄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 金崎めぐみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 池田崇之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 吉冨泰央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 水沼有威子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 川北恵美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 笹岡利安

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 和田努

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kitada Munehiro 北田 宗弘

KITADA Munehiro 北田 宗弘

Research Projects

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Co-Researchers

Elucidation of the mechanism of cyclic and intermittent very low-protein diet on chronic kidney disease that has high risk of its progressionPrincipal Investigator

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Elucidation of the role of cysteinyl leukotriene receptor1 on advanced diabetic kidney diseasePrincipal Investigator

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New therapeutic strategy for diabetic kidney disease by inhibiting MGAT

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Translational research for ensuring acceptability of lifestyle management of older people with diabetes

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Elucidation of role of changing S-adenosylmethionine (SAM) metabolism for the pathogenesis of diabetic kidney diseasePrincipal Investigator

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The role of Sirtuin on diabetic nephropatfunctionhy based on maintaining mitochondrial

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Alteration in nutrient sensing and metabolic diseases

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Elucidation of mechanism by which low protein diet suppresses progression of diabetic nephropathy through activation of autophagy in tubular cellsPrincipal Investigator

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[Book] 特集 糖尿病の食事療法を極める 蛋白質の摂取量と糖尿病の管理―糖尿病性腎症における低蛋白質食を考える―2019

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[Book] 特集 健康長寿を目指した食事療法の設定根拠とその実際 糖尿病性腎症患者の食事療法―低蛋白質食を中心に―2019

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[Journal Article] 糖尿病性腎臓病に対する包括的治療のポイント2023

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[Journal Article] The Role of CD38 in the Pathogenesis of Cardiorenal Metabolic Disease and Aging, an Approach from Basic Research2023

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[Journal Article] Adenosine/adenosine type?1 receptor signaling pathway did not play dominant roles on the influence of sodium?glucose cotransporter?2 inhibitor in the kidney of bovine serum albumin‐overloaded streptozotocin‐induced diabetic mice2022

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[Journal Article] 糖尿病性腎臓病の食事療法～摂取タンパク質量の制限からタンパク源を重視した食事パターンへ～2022

Author(s)

Journal Title

Kitada Munehiro 北田宗弘

KITADA Munehiro 北田宗弘

[Book] 特集糖尿病の食事療法を極める　蛋白質の摂取量と糖尿病の管理―糖尿病性腎症における低蛋白質食を考える―2019

[Book] 特集健康長寿を目指した食事療法の設定根拠とその実際　糖尿病性腎症患者の食事療法―低蛋白質食を中心に―2019

[Journal Article] 糖尿病性腎症（DKD)の治療　食事療法（保存期）2021