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GOTO Eiji  後藤 栄治

ORCIDConnect your ORCID iD *help
Researcher Number 40435649
Affiliation (based on the past Project Information) *help 2018: 大阪市立大学, 大学院医学研究科, 助教
2012 – 2014: 群馬大学, 生体調節研究所, 助教
2007 – 2011: 独立行政法人理化学研究所, 感染免疫応答研究チーム, 研究員
2009: 感染免疫応答研究チーム, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / General medical chemistry / Laboratory animal science
Except Principal Investigator
Biological Sciences / Immunology
Keywords
Principal Investigator
ユビキチン / NF-κB / E3ユビキチンリガーゼ / 胎生致死 / ミトコンドリア
Except Principal Investigator
ユビキチンリガーゼ / 遺伝子改変マウス / アポトーシス / ユビキチン化 / エンドサイトーシス … More / B7-2 / MHC class I / MHC class II / 樹状細胞 / MHC II / 細胞増殖 / T細胞 / 循環器 / 中枢神経 / 免疫 / 胎生致死 / MARCH-V / ミトコンドリア / 免疫制御 / B7分子 / MHC分子 / ドラッグデリバリー / 人工免疫制御 / E3ユビキチンリガーゼ / 免疫回避 / 抗原提示細胞 / リソソーム / 蛋白分解 / 細胞内輸送 / ユビキチン鎖 / ユビキチン / カポジ肉腫関連ヘルペスウイルス Less
  • Research Projects

    (7 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (4 People)
  •  T細胞における直鎖状ユビキチン鎖形成を介した新規NF-κB活性化機構の解析Principal Investigator

    • Principal Investigator
      後藤 栄治
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Osaka City University
  •  Regulation of NF-kappaB signalling by MARCH9Principal Investigator

    • Principal Investigator
      GOTO EIJI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Gunma University
  •  Analysis of the physiology of mitochondrial morphology control by MARCH-VPrincipal Investigator

    • Principal Investigator
      GOTO Eiji
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Gunma University
      The Institute of Physical and Chemical Research
  •  T細胞ホメオスターシスにおけるミトコンドリア形態制御の関与に関する検討

    • Principal Investigator
      石戸 聡
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Exploration into MHC class II-mediated immune regulation

    • Principal Investigator
      ISHIDO Satoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  E3ユビキチンリガーゼを用いた新たな免疫制御法の試み

    • Principal Investigator
      石戸 聡
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  カポジ肉腫関連ヘルペスウイルスによる免疫回避機構の解析

    • Principal Investigator
      ISHIDO Satoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research

All 2018 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

  • [Journal Article] Structural and functional analyses of DNA-sensing and immune activation by human cGAS2013

    • Author(s)
      Kazuki Kato, Ryohei Ishii, Eiji Goto, Ryuichiro Ishitani, Fuminori Tokunaga, and Osamu Nureki
    • Journal Title

      PLoS One

      Volume: 8 Issue: 10 Pages: e76983-e76983

    • DOI

      10.1371/journal.pone.0076983

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22117006, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25670137, KAKENHI-PROJECT-25860207
  • [Journal Article] The inter-transmembrane region of KSHV MIR2 contributes to B7-2 downregulation.2012

    • Author(s)
      Kajikawa, M.
    • Journal Title

      J. Virol.

      Volume: 86 Issue: 9 Pages: 5288-5296

    • DOI

      10.1128/jvi.00219-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117528, KAKENHI-PROJECT-23700517
  • [Journal Article] The inter-transmembrane region of KSHV MIR2 contributes to B7-2 downregulation2012

    • Author(s)
      Kajikawa, M., Li PC., Goto, E., Miyashita, N, Aoki-Kawasumi, M, Mito-Yoshida, M, Ikegaya, M., Sugita, Y. and Ishido, S
    • Journal Title

      J. Virol

      Volume: 86(9) Pages: 5288-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane2012

    • Author(s)
      Tanno, H., Yamaguchi, T., Goto, E., Ishido, S. and Komada, M
    • Journal Title

      Mol. Biol. Cell

      Volume: 23(7) Pages: 1343-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.2012

    • Author(s)
      Kensche, T.
    • Journal Title

      J. Biol. Chem.

      Volume: 287 Issue: 28 Pages: 23626-23634

    • DOI

      10.1074/jbc.m112.347195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249008, KAKENHI-PROJECT-23390070, KAKENHI-PROJECT-23657075, KAKENHI-PROJECT-23700517, KAKENHI-PLANNED-22117006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002
  • [Journal Article] Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation2012

    • Author(s)
      Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O
    • Journal Title

      EMBO J.

      Volume: 31 Issue: 19 Pages: 3856-3870

    • DOI

      10.1038/emboj.2012.241

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22249008, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23390070, KAKENHI-PROJECT-23591263, KAKENHI-PROJECT-23657075, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-23700517, KAKENHI-PROJECT-24659136, KAKENHI-PLANNED-22117006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002
  • [Journal Article] The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane2012

    • Author(s)
      Tanno, H.
    • Journal Title

      Mol.Biol.Cell

      Volume: 23 Issue: 7 Pages: 1343-1353

    • DOI

      10.1091/mbc.e11-09-0817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370068, KAKENHI-PUBLICLY-23113710, KAKENHI-PROJECT-23700517, KAKENHI-PROJECT-24650610, KAKENHI-PUBLICLY-23117528, KAKENHI-PLANNED-24112003
  • [Journal Article] MARCH-I : A New Regulator of Dendritic Cell Function2010

    • Author(s)
      Satoshi Ishido, Yohei Matsuki, Eiji Goto, Mizuho Kajikawa, Mari Ohmura-Hoshino
    • Journal Title

      Molecules and Cells 29

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] MARCH-I : A New Regulator of Dendritic Cell Function2010

    • Author(s)
      Satoshi Ishido, Yohei Matsuki, Eiji Goto, Mizuho Kajikawa, Mari Ohmura-Hoshino
    • Journal Title

      Molecules and Cells 29

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20060034
  • [Journal Article] Contribution of K11-linked ubiquitination to MIR2-mediated MHC class I internalization2010

    • Author(s)
      Goto, E., Yamanaka, Y., Ishikawa, A., Aoki-Kawasumi, M., Mito-Yoshida, M., Ohmura-Hoshino, M., Matsuki, Y., Kajikawa, M., Hirano, H. and Ishido, S
    • Journal Title

      J. Biol. Chem

      Volume: 285(46) Pages: 35311-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] Contribution of K11-linked ubiquitination to MIR2-mediated MHC class I internalization.2010

    • Author(s)
      Goto, E.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 35311-35319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] MARCH-I : a new regulator of dendritic cell function2010

    • Author(s)
      Ishido, S., Matsuki, Y., Goto, E., Kajikawa, M. and Ohmura-Hoshino, M
    • Journal Title

      Mol. Cells

      Volume: 29(3) Pages: 229-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] Contribution of K11-linked ubiquitination to MIR2-mediated MHC class I internalization.2010

    • Author(s)
      Goto, E.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 35311-35319

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025039
  • [Journal Article] MARCH-I : A New Regulator of Dendritic Cell Function2010

    • Author(s)
      Satoshi Ishido, Yohei Matsuki, Eiji Goto, Mizuho Kajikawa, Mari Ohmura-Hoshino
    • Journal Title

      Molecules and Cells 29

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025039
  • [Journal Article] Requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells2009

    • Author(s)
      Mari Ohmura-Hoshino, Yohei Matsuki, Mari Mito-Yoshida, Eiji Goto, Masami Aoki-Kawasumi, Manabu Nakayama, Osamu Ohara, Satoshi Ishido
    • Journal Title

      THE JOURNAL OF IMMUNOLOGY 83

      Pages: 6893-6897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20060034
  • [Journal Article] E3 ubiquitin for MHC molecules2009

    • Author(s)
      Ishido S, Goto E, Matsuki Y, Ohmura-Hoshino M.
    • Journal Title

      Current Opinion in Immunology 21

      Pages: 78-83

    • Data Source
      KAKENHI-PROJECT-20060034
  • [Journal Article] Requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells2009

    • Author(s)
      Mari Ohmura-Hoshino, Yohei Matsuki, Mari Mito-Yoshida, Eiji Goto, Masami Aoki-Kawasumi, Manabu Nakayama, Osamu Ohara, Satoshi Ishido
    • Journal Title

      THE JOURNAL OF IMMUNOLOGY 83

      Pages: 6893-6897

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21025039
  • [Journal Article] Cutting edge : Requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cell2009

    • Author(s)
      Ohmura-Hoshino, M., Matsuki, Y., Mito-Yoshida, M., Goto, E., Aoki-Kawasumi, M., Nakayama, M., Ohara, O. and Ishido, S
    • Journal Title

      J. Immunol

      Volume: 183(11) Pages: 6893-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] E3 ubiquitin ligases for MHC molecules2009

    • Author(s)
      Ishido S, Goto E, Matsuki Y, Ohmura-Hoshino M.
    • Journal Title

      Current Opinion in Immunology 21

      Pages: 78-83

    • Data Source
      KAKENHI-PROJECT-19041071
  • [Journal Article] Requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells2009

    • Author(s)
      Mari Ohmura-Hoshino, Yohei Matsuki, Mari Mito-Yoshida, Eiji Goto, Masami Aoki-Kawasumi, Manabu Nakayama, Osamu Ohara, Satoshi Ishido
    • Journal Title

      THE JOURNAL OF IMMUNOLOGY 83

      Pages: 6893-6897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Journal Article] An Excellent Monitoring System for. Surface Ubiquitination-Induced Internalization in Mammals2008

    • Author(s)
      後藤 栄治、石戸 聡
    • Journal Title

      PLOS ONE 3(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041071
  • [Patent] c-MIRを機能評価できる細胞株2007

    • Inventor(s)
      石戸 聡 後藤 栄治 水戸 麻理
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2007-05-15
    • Data Source
      KAKENHI-PROJECT-19041071
  • [Presentation] TCRシグナルにおける直鎖状ユビキチン化形成の数理モデル解析2018

    • Author(s)
      後藤 栄治、濱田 大輔、鈴木 貴、徳永 文稔
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K06918
  • [Presentation] Molecular basis for immunoreceptor recognition by MIR2 ubiquitin ligase of KSHV2011

    • Author(s)
      梶川瑞穂、Pai-Chi Li、後藤英治、杉田有治、石戸聡
    • Organizer
      International Union of Microbiological Societies 2011 Congress(IUMS 2011)
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Presentation] 新規ユビキチン結合因子Ankrd13によるエンドサイトーシス制御2011

    • Author(s)
      丹野秀崇、山口鉄平、後藤栄治、石戸聡、駒田雅之
    • Organizer
      第84回日本生化学会大会・シンポジウム-拡大するユビキチンバイオロジー
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23700517
  • [Presentation] カポジ肉腫関連ヘルペスウイルスMIR2による新規ポリユビキチン鎖を介したMHCclass I制御機構の解析2009

    • Author(s)
      後藤栄治
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PUBLICLY-21025039
  • [Presentation] カポジ肉腫関連ヘルペスウイルスMIR2による新規ポリユビキチン鎖を介したMHCclass I制御機構の解析2009

    • Author(s)
      後藤栄治
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-21390156
  • [Presentation] カポジ肉腫関連ヘルペスウイルスMIR2による新規ポリユビキチン鎖を介したMHCclass I制御機構の解析2009

    • Author(s)
      後藤栄治
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-20060034
  • [Presentation] KSHV MIR1とMIR2による抑制機構における相違点に関する検討2008

    • Author(s)
      後藤 栄治
    • Organizer
      第56回日本ウイルス学会
    • Place of Presentation
      岡山
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19041071
  • [Presentation] KSHV MIR1とMIR2による抑制機構における相違点に関する検討2008

    • Author(s)
      後藤 栄治
    • Organizer
      第56回日本ウイルス学会
    • Place of Presentation
      岡山
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-20060034
  • [Presentation] 主要組織適合抗原の新たな制御分子群2007

    • Author(s)
      後藤 栄治
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学学会合同大会(BMB2007)
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-19041071
  • [Presentation] CRISPR/Cas9法を用いたLUBAC欠損細胞の作製とNF-κB活性制御への影響

    • Author(s)
      後藤栄治
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25860207
  • 1.  ISHIDO Satoshi (10273781)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 15 results
  • 2.  ISHITANI Ryuichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  濡木 理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  徳永 文稔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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