Kimura Hideharu 木村英晴

… Alternative Names

KIMURA Hideharu 木村英晴

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Researcher Number	40444202
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2019 – 2022: 金沢大学, 附属病院, 講師 2018: 金沢大学, 医学系, 助教 2017: 金沢大学, 医学(系)研究科(研究院), 准教授 2014 – 2016: 金沢大学, 医学系, 助教 2011 – 2012: 近畿大学, 医学部, 講師 2009: Kanazawa University, 医学部, 講師 2008: Kanazawa University, 医学系研究科, 特任准教授
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnostics / Tumor diagnosis / Respiratory organ internal medicine Except Principal Investigator Tumor therapeutics / Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine
Keywords	Principal Investigator 肺癌 / 血中DNA / 血中遊離DNA / 非小細胞肺癌 / cfDNA / 小細胞肺癌 / 循環腫瘍細胞 / 血管新生阻害薬 / バイオマーカー / IL-8 … More / L-8 / 血管新生 / VEGFR阻害剤 / 遺伝子変異 / 癌 … More Except Principal Investigator 肺癌 / cMet / 細胞障害性抗癌薬 / Kras変異陽性肺癌 / EGFR遺伝子変異陽性肺癌 / HMGB1 / カルレティキュリン / パクリタキセル / ペメトレキセド / シスプラチン / オートファジー / 細胞老化 / アポトーシス / 免疫原性細胞死 / MET / 発現解析 / cMET / Met阻害剤 / HGF / シグナル伝達 / 個別化療法 / 非小細胞肺癌 / ｃMet / c-Met遺伝子増幅 / TP53変異 / 次世代シークエンス / エルロチニブ / EGFR遺伝子変異陰性 / Toppisomerase I / MET遺伝子 / Lung cancer / Topoisomerase I Less

Immunogenic cell death by cytotoxic agents
- Principal Investigator
  
  Kasahara Kazuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
  Kanazawa University
Establishment of monitoring method using cfDNA gene mutation profile in patients with malignant tumorsPrincipal Investigator
- Principal Investigator
  
  Kimura Hideharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kanazawa University
Personalized therapy targeting Met gene in lung cancer
- Principal Investigator
  
  Kasahara Kazuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Identification of Novel Treatment Targets and Biomarkers for Small-Cell Lung Cancer by Circulating Tumor Cell AnalysisPrincipal Investigator
- Principal Investigator
  
  Kimura Hideharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kanazawa University
Regulation of Topisomerase I activity by cMet in lung cancer
- Principal Investigator
  
  Kasahara Kazuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University
Analysis of predictive biomarker of Erlotinib to non-small cell lung cancer without EGFR mutation
- Principal Investigator
  
  Sone Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University
VEGFR2 tyrosine kinase inhibitor (VEGFR2-TKI)-resistant cancer tissue from a cancer-bearing mouse modelPrincipal Investigator
- Principal Investigator
  
  KIMURA Hideharu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Kinki University
Detection of tumor-derived mutations in circulating DNAPrincipal Investigator
- Principal Investigator
  
  KIMURA Hideharu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2009 2008 Other

All Journal Article Presentation Book

[Book] 遺伝子変異検査. 「新臨床腫瘍学-がん薬物療法専門医のために-」(NPO法人日本臨床腫瘍学会編)2009
- Author(s)
  木村英晴
- Publisher
  南行堂
- Data Source
  KAKENHI-PROJECT-20790565
[Book] 「新臨床腫瘍学-がん薬物療法専門医のために-」(NPO法人日本臨床腫瘍学会編)2009
- Author(s)
  木村英晴
- Publisher
  遺伝子変異検査
- Data Source
  KAKENHI-PROJECT-20790565
[Book] 遺伝子変異検査.「新臨床腫瘍学(改訂第 3版)」(日本臨床腫瘍学会編)
- Author(s)
  木村英晴
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis2021
- Author(s)
  Koba Hayato、Kimura Hideharu、Yoneda Taro、Sone Takashi、Ohkura Noriyuki、Hara Johsuke、Hosomichi Kazuyoshi、Tajima Atsushi、Kasahara Kazuo
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 8398-8398
- DOI
  10.1038/s41598-021-87094-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07727, KAKENHI-PROJECT-17H01886
[Journal Article] Late-onset programmed cell death protein-1 inhibitor-induced pneumonitis after cessation of nivolumab or pembrolizumab in patients with advanced non-small cell lung cancer: a case series2021
- Author(s)
  Kimura Hideharu、Sone Takashi、Araya Tomoyuki、Murata Akari、Yamamura Kenta、Ohkura Noriyuki、Hara Johsuke、Abo Miki、Kasahara Kazuo
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 10 Issue: 3 Pages: 1576-1581
- DOI
  10.21037/tlcr-20-582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07727, KAKENHI-PROJECT-17H01886
[Journal Article] Successful Treatment of Advanced Thymic Carcinoma with Carboplatin plus nab-Paclitaxel and Maintenance Monotherapy with nab-Paclitaxel: Two Case Reports2020
- Author(s)
 Araya Tomoyuki、Kita Toshiyuki、Matsuoka Hiroki、Sakai Tamami、Kimura Hideharu、Kasahara Kazuo
- Journal Title
 
 Case Reports in Oncology
 
 Volume: 13 Issue: 3 Pages: 1506-1512
- DOI
 10.1159/000510894
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K07727
[Journal Article] Severe coronavirus disease 2019 (COVID‐19) pneumonia patients treated successfully with a combination of lopinavir/ritonavir plus favipiravir: Case series2020
- Author(s)
  Koba Hayato、Yoneda Taro、Kaneda Tomoya、Ueda Tsukasa、Kimura Hideharu、Kasahara Kazuo
- Journal Title
  
  Clinical Case Reports
  
  Volume: 8 Issue: 12 Pages: 3143-3148
- DOI
  10.1002/ccr3.3358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07727
[Journal Article] Real-World Efficacy of First-Line Pembrolizumab in Patients With Advanced or Recurrent Non?Small-Cell Lung Cancer and High PD-L1 Tumor Expression2020
- Author(s)
  Tambo Yuichi、Sone Takashi、Shibata Kazuhiko、Nishi Kouichi、Shirasaki Hiroki、Yoneda Taro、Araya Tomoyuki、Kase Kazumasa、Nishikawa Shingo、Kimura Hideharu、Kasahara Kazuo
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: XX Issue: 5 Pages: 1-4
- DOI
  10.1016/j.cllc.2020.02.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606, KAKENHI-PROJECT-19K07727
[Journal Article] Long-lasting responses after discontinuation of nivolumab treatment for reasons other than tumor progression in patients with previously treated, advanced non-small cell lung cancer.2019
- Author(s)
  Kimura H, Araya T, Yoneda T, Shirasaki H, Kurokawa K, Sakai T, Koba H, Tambo Y, Nishikawa S, Sone T, Kasahara K.
- Journal Title
  
  Cancer Commun (Lond).
  
  Volume: 39 Issue: 1 Pages: 78-78
- DOI
  10.1186/s40880-019-0423-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07727
[Journal Article] A case of EGFR mutation-positive lung adenocarcinoma in which the T790M allele fraction was increased by repeated EGFR-TKI treatment.2019
- Author(s)
  Kimura H, Amino Y, Koba H, Tambo Y, Ohkura N, Hara J, Sone T, Kasahara K.
- Journal Title
  
  Cancer Commun (Lond).
  
  Volume: 39 Issue: 1 Pages: 67-67
- DOI
  10.1186/s40880-019-0413-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07727, KAKENHI-PROJECT-17K09606
[Journal Article] Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstitial Lung Disease: A Retrospective Study.2019
- Author(s)
  Araya T, Kita T, Ueda T, Terada N, Sakai T, Yamamura K, Kurokawa K, Uchida Y, Sone T, Kimura H, Kasahara K
- Journal Title
  
  Canadian Respiratory Journal
  
  Volume: Mar Pages: 1-7
- DOI
  10.1155/2019/5315903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Lung cancer in connective tissue disease-associated interstitial lung disease: clinical features and impact on outcomes2018
- Author(s)
  Watanabe Satoshi、Saeki Keigo、Waseda Yuko、Murata Akari、Takato Hazuki、Ichikawa Yukari、Yasui Masahide、Kimura Hideharu、Hamaguchi Yasuhito、Matsushita Takashi、Yamada Kazunori、Kawano Mitsuhiro、Furuichi Kengo、Wada Takashi、Kasahara Kazuo
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 10 Issue: 2 Pages: 799-807
- DOI
  10.21037/jtd.2017.12.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Role of prostaglandin I2 in the bronchoconstriction-triggered cough response in guinea pigs2018
- Author(s)
  Sakai Tamami、Hara Johsuke、Yamamura Kenta、Okazaki Akihito、Ohkura Noriyuki、Sone Takashi、Kimura Hideharu、Abo Miki、Yoshimura Kenichi、Fujimura Masaki、Kasahara Kazuo、Nakao Shinji
- Journal Title
  
  Experimental Lung Research
  
  Volume: 44 Issue: 10 Pages: 455-463
- DOI
  10.1080/01902148.2019.1590883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Selective gene amplification to detect the T790M mutation in plasma from patients with advanced non-small cell lung cancer (NSCLC) who have developed epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance2018
- Author(s)
  Shingo Nishikawa, Hideharu Kimura, Hayato Koba, Taro Yoneda, Satoshi Watanabe, Tamami Sakai, Johsuke Hara, Takashi Sone, Kazuo Kasahara, Shinji Nakao
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 10 Issue: 3 Pages: 1431-1439
- DOI
  10.21037/jtd.2018.01.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Imatinib ameliorates bronchiolitis obliterans via inhibition of fibrocyte migration and differentiation.2017
- Author(s)
  1.4.Watanabe S, Kasahara K, Waseda Y, Takato H, Nishikawa S, Yoneda T, Hara J, Sone T, Abo M, Kimura H, Nakao S.
- Journal Title
  
  J Heart Lung Transplant.
  
  Volume: 36 Issue: 2 Pages: 138-147
- DOI
  10.1016/j.healun.2016.06.001
- NAID
  120005983030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] Severe pneumonitis after nivolumab treatment in a patient with melanoma.2016
- Author(s)
  1.5.Watanabe S, Kimura H, Takato H, Waseda Y, Hara J, Sone T, Abo M, Maeda S, Matsushita T,Kasahara K.
- Journal Title
  
  Allergol Int.
  
  Volume: 65 Issue: 4 Pages: 487-489
- DOI
  10.1016/j.alit.2016.04.009
- NAID
  130005431308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] A case of gingival cancer with pulmonary metastases that developed complete atrioventricular block and ventricular fibrillation as a result of myocardial metastases.2016
- Author(s)
  Yoneda T, Kase K2, Amino Y, Ogawa N, Watanabe S, Hara J, Abo M, Sone T, Kimura H, Kasahara K
- Journal Title
  
  Clin Case Rep.
  
  Volume: 10 Issue: 12 Pages: 1075-1081
- DOI
  10.1002/ccr3.695
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] 1.2.Impact of Tight Junction Protein ZO-1 and TWIST Expression on Postoperative Survival of Patients with Hepatocellular Carcinoma.2016
- Author(s)
  Nagai T, Arao T, Nishio K, Matsumoto K, Hagiwara S, Sakurai T, Minami Y, Ida H, Ueshima K, Nishida N, Sakai K, Saijo N, Kudo K, Kaneda H, Tamura D, Aomatsu K, Kimura H, Fujita Y, Haji S, Kudo M.
- Journal Title
  
  Dig Dis.
  
  Volume: 34 Issue: 6 Pages: 702-707
- DOI
  10.1159/000448860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430142, KAKENHI-PROJECT-15K09028, KAKENHI-PROJECT-16K09382
[Journal Article] 1.1.A Rapid and Sensitive Method for Detection of the T790M Mutation of EGFR in Plasma DNA.2016
- Author(s)
  Kimura H, Nishikawa S, Koba H, Yoneda T, Sone T, Kasahara K.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 924 Pages: 171-174
- DOI
  10.1007/978-3-319-42044-8_31
- ISBN
  9783319420424, 9783319420448
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142, KAKENHI-PROJECT-26430159
[Journal Article] Postoperative Recurrence of Invasive Thymoma with Cold Agglutinin Disease and Autoimmune Hemolytic Anemia2016
- Author(s)
  1.3.Yoneda T, Koba H, Tanimura K, Ogawa N, Watanabe S, Hara J, Abo M, Sone T, Kimura H, Kasahara K.
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 18 Pages: 2685-2689
- DOI
  10.2169/internalmedicine.55.6654
- NAID
  130005414857
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] Imatinib for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  1.1.Watanabe S, Waseda Y, Kimura H, Takato H, Ohata K, Kondo Y, Kasahara K, Nakao S.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: 50 Issue: 9 Pages: 1250-1252
- DOI
  10.1038/bmt.2015.120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142, KAKENHI-PROJECT-26430159
[Journal Article] Analytical performance of the cobas EGFR2014
- Author(s)
  Kimura H, Nagao T, 他6名
- Journal Title
  
  Mutation assay for Japanese non-small-cell lung cancer
  
  Volume: 83 Issue: 3 Pages: 329-33
- DOI
  10.1016/j.lungcan.2013.12.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590416, KAKENHI-PROJECT-24240122, KAKENHI-PROJECT-26430142
[Journal Article] Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.2014
- Author(s)
  Togashi Y, Arao T, Kato H, Matsumoto K, Terashima M, Hayashi H, de Velasco MA, Fujita Y, Kimura H, Yasuda T, Shiozaki H, Nishio K.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 2962-2973
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] Biomarkers of reactive resistance and early disease progression during chemotherapy plus bevacizumab treatment for colorectal carcinoma.2014
- Author(s)
  Hayashi H, Arao T, Matsumoto K, Kimura H, Togashi Y, Hirashima Y, Horita Y, Iwasa S, Okita NT, Honma Y, Takashima A, Kato K, Hamaguchi T, Shimada Y, Nakagawa K, Nishio K, Yamada Y.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 2588-2595
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma.2013
- Author(s)
  Arao T, Ueshima K, Matsumoto K, Nagai T, Kimura H, Hagiwara S, Sakurai T, Haji S, Kanazawa A, Hidaka H, Iso Y, Kubota K, Shimada M, Utsunomiya T, Hirooka M, Hiasa Y, Toyoki Y, Hakamada K, Yasui K, Kumada T, Toyoda H, Sato S, Hisai H, Kuzuya T, Tsuchiya K, Izumi N, Arii S, Nishio K, Kudo M.
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 4 Pages: 1407-1415
- DOI
  10.1002/hep.25956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590470, KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-23701089, KAKENHI-PROJECT-23790820, KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-24591990, KAKENHI-PROJECT-24592003
[Journal Article] Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma.2013
- Author(s)
  Kato H, Arao T, Matsumoto K, Fujita Y, Kimura H, et al.
- Journal Title
  
  Int J Oncol
  
  Volume: 42(4) Pages: 1151-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer.2013
- Author(s)
  Hayashi, H., Arao, T., Togashi, Y., Kato, H., Velasco, MA., Kimura, H., Matsumoto, K., Tanaka, K., Okamoto, I., Ito, A., Yamada, Y., Nakagawa, K., Nishio, K.
- Journal Title
  
  Oncogene
  
  Volume: E-pub ahead or print Issue: 2 Pages: 199-208
- DOI
  10.1038/onc.2013.547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24240122, KAKENHI-PROJECT-24590492, KAKENHI-PROJECT-25350979, KAKENHI-PROJECT-26430142
[Journal Article] Slug is upregulated during wound healing and regulates cellular phenotypes in corneal epithelial cells.2012
- Author(s)
  Aomatsu K, Arao T, Abe K, Kodama A, Sugioka K, Matsumoto K, Kudo K, Kimura H, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 53 Pages: 751-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells.2012
- Author(s)
  Furuta K, Arao T, Sakai K, Kimura H, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 221-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Highly sensitive detection of EGFR T790M mutation using colony hybridization predicts favorable prognosis of patients with lung cancer harboring activating EGFR mutation.2012
- Author(s)
  Fujita Y, Suda K, Kimura H, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 7 Pages: 1640-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Plasma concentrations of angiogenesis-related molecules in patients with pancreatic cancer2012
- Author(s)
  Sakamoto H, Kimura H, Sekijima M, Matsumoto K, Arao T, Chikugo T, Yamada Y, Kitano M, Ito A, Takeyama Y, Kudo M, Nishio K
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 42 Issue: 2 Pages: 105-112
- DOI
  10.1093/jjco/hyr178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590764, KAKENHI-PROJECT-23701089, KAKENHI-PROJECT-23701106
[Journal Article] MET increases the sensitivity of gefitinib-resistant cells to SN-38, an active metabolite of irinotecan, by up-regulating the topoisomerase I activity.2012
- Author(s)
  Sakai A, Kasahara K, Ohmori T, Kimura H, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 7 Pages: 1337-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients.2012
- Author(s)
  Matsuoka H, Arao T, Makimura C, Takeda M, Kiyota H, Tsurutani J, Fujita Y, Matsumoto K, Kimura H, et al.
- Journal Title
  
  Oncol Rep
  
  Volume: 27 Pages: 1393-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] A novel mass spectrometry-based assay for diagnosis of EML4-ALK-positive non-small cell lung cancer.2012
- Author(s)
  Sakai K, Okamoto I, Takezawa K, Hirashima T, Kaneda H, Takeda M, Matsumoto K, Kimura H, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 7 Pages: 913-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] SRPX2 is a novel chondroitin sulfate proteoglycan that is overexpressed in gastrointestinal cancer.2012
- Author(s)
  Tanaka K, Arao T, Tamura D, Aomatsu K, Furuta K, Matsumoto K, Kaneda H, Kudo K, Fujita Y, Kimura H, et al.
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Clinical outcomes of thoracic radiotherapy for locally advanced NSCLC with EGFR mutations or EML4-ALK rearrangement.2012
- Author(s)
  Hayashi H, Okamoto I, Kimura H, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 32 Pages: 4533-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Prospective study evaluating the plasma concentrations of twenty-six cytokines and response to morphine treatment in cancer patients.2011
- Author(s)
  Makimura C, Arao T, Matsuoka H, Takeda M, Kiyota H, Tsurutani J, Fujita Y, Matsumoto K, Kimura H, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 4561-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Serum heparan sulfate concentration is correlated with the failure of epidermal growth factor receptor tyrosine kinase inhibitor treatment in patients with lung adenocarcinoma.2011
- Author(s)
  Nishio M, Yamanaka T, Matsumoto K, Kimura H, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 6 Pages: 1889-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma.2011
- Author(s)
  Nagai T, Arao T, Furuta K, Sakai K, Kudo K, Kaneda H, Tamura D, Aomatsu K, Kimura H, et al.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 10 Pages: 169-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701089
[Journal Article] Eosinophilic pneumonia and thoracic metastases as an initial manifestaion of prostatic carcinoma.2008
- Author(s)
  Ishiguro T, Kimura H, Araya T, et al.
- Journal Title
  
  Internal Med 47
  
  Pages: 1419-1423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790565
[Journal Article] Eosinophilic pneumonia and thoracic metastases as an initial manifestaion of prostatic carcinoma2008
- Author(s)
  Ishiguro T, Kimura H, et.al.
- Journal Title
  
  Intern Med 47
  
  Pages: 1419-1423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Molecular genetic characteristics of tumor-derived gene alterations in cfDNA.2019
- Author(s)
  Kimura H,Koba H, Kasahara K.
- Organizer
  11th International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07727
[Presentation] Detection of tumor-associated gene mutations in cell-free DNA of early-stage non-small cell lung cancer patients.2019
- Author(s)
  Kimura H,Koba H, Kasahara K.
- Organizer
  11th International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07727
[Presentation] Next-generation sequencing analysis identifies genomic alterations in pathological morphologies  a case report of pulmonary carcinosarcoma harboring EGFR mutations.2016
- Author(s)
  Hayato Koba, Hideharu Kimura, Shingo Nishikawa, Yuichi Tambo, Takashi Sone, Atsushi Tajima,  Kazuo Kasahara
- Organizer
  ESMO ASIA 2016
- Place of Presentation
  シンガポール
- Year and Date
  2016-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142
[Presentation] MET過剰発現細胞ではtopoisomerase-I 蛋白発現が亢進する2016
- Author(s)
  米田太郎　木場隼人　西川晋吾　曽根　崇　木村英晴　笠原寿郎
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-26430159
[Presentation] Non-invasive analysis for T790M mutations of EGFR using a selective amplification method2015
- Author(s)
  Shingo Nishikawa, Hideharu Kimura, Hayato Koba, Taro Yoneda, Takashi Sone, Chris Booth, Andrew Webb, Kazuo Kasahara
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142
[Presentation] Characteristics of HS6ST2 expression in colorectal cancer.2012
- Author(s)
  Kimura H
- Organizer
  American Association for Cancer Research 102nd Annual Meeting 2012
- Place of Presentation
  Chicago, IL
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] WJOG6110B (ELTOP): Randomized phase II trial comparing trastuzumab plus capecitabine (HX) and lapatinib plus capecitabine (LX) in HER2-positive metastatic breast cancer patients previously treated with trastuzumab and taxanes2012
- Author(s)
  Takano T, Kimura H, Nishio K, et al.
- Organizer
  American Society of Clinical Oncology Annual Meeting 2011
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] Characteristics of HS6ST2 expression in colorectal cancer2012
- Author(s)
  Kimura H, Hatabe S, Arao T, et al.
- Organizer
  merican Association for Cancer Research 102nd Annual Meeting 2012
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] 大腸がんにおけるHS6ST2発現とその臨床的意義2011
- Author(s)
  木村英晴
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋市　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] Serum concentrations of angiogenesis-related molecules in patients with pancreatic cancer2011
- Author(s)
  Kimura H
- Organizer
  American Association for Cancer Research 102nd Annual Meeting 2011
- Place of Presentation
  Florida
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] Serum concentrations of angiogenesis-related molecules in patients with pancreatic cancer2011
- Author(s)
  Kimura H, Sakamoto H, Nagai T, et al.
- Organizer
  American Association for Cancer Research 102nd Annual Meeting 2011
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] Impact of sermu HGF on treatment response to EGFR tyrosine kinase inhibitors in patients with non-small-cell lung adenocarcinoma2011
- Author(s)
  Kimura H, Arao T, Matsutmoto K, et al.
- Organizer
  The Joint International Meeting Sponsored by The Japanese Society for Interferon and Cytokine Research The Japanese Scociety for Macrophage Molecular and Cell Biology.
- Data Source
  KAKENHI-PROJECT-23701089
[Presentation] Using whole genome amplification of plasma DNA can increase the success rate of tumor-derived mutation detection in patients with advanced non-small cell lung cancer(NSCLC)2009
- Author(s)
  Kimura H
- Organizer
  CNAPS-VI Hong Kong
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Detection of micro-dissemination of cancer cells by testing for progastrin-releasing peptide expression in the peripheral blood of SCLC patients2009
- Author(s)
  Kimura H
- Organizer
  AACR Annual Meeting 2009
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Detection of micro-dissemination of cancer cells by testing for progastrin-releasing peptide expression in the peripheral blood of SCLC patients.2009
- Author(s)
  Kimura H
- Organizer
  AACR Annual Meeting 2009
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Using whole genome amplification of plasma DNA can increase the success rate of tumor-derived mutation detection in patients with advanced non-small cell lung cancer(NSCLC).2009
- Author(s)
  Kimura H
- Organizer
  CNAPS-VI Hong Kong
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] 腫瘍代替サンプルを用いた癌由来遺伝子変異の検出2008
- Author(s)
  木村英晴
- Organizer
  第49回日本肺癌学会総会
- Place of Presentation
  北九州
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Detection of EGFR mutations in accessible tissue that is a potential surrogate for tissue2008
- Author(s)
  Sakai A, Kimura H, et.al.
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Suitable Sourse of DNA for a Bool-based test for EGFR Mutations.2008
- Author(s)
  Kimura H, et al.
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Suitable Sourse of DNA for a Bool-based test for EGFR Mutations.2008
- Author(s)
  木村英晴
- Organizer
  第67回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] 腫瘍代替サンプルを用いた腫瘍由来変異遺伝子検出方法の確立、使用検体の検討2008
- Author(s)
  木村英晴
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Suitable Sourse of DNA for a Bool-based test for EGFR Mutations2008
- Author(s)
  木村英晴
- Organizer
  第67回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] ゲフィチニブによる皮膚障害の発現を予測する因子としての血漿中サイトカイン測定の有用性2008
- Author(s)
  木村英晴
- Organizer
  第4回日本臨床プロテオーム研究会
- Place of Presentation
  大阪
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Suitable Sourse of DNA for a Bool-based test for EGFR Mutations2008
- Author(s)
  Kimura H, Sakai A, Kasahara K.
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-20790565
[Presentation] Noninvasive analysis of acquired resistance to EGFR-TKI
- Author(s)
  Hideharu Kimura, Makoto Nishio, Tsutomu Daito, Kazuto Nishio.
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26430142
[Presentation] Retrospective analysis of prognostic factors in non-small cell lung cancer with EGFR mutations.
- Author(s)
  Shingo Nishikawa, Takashi Sone, Taro Yoneda, Kazuhiko Shibata, Koji Kurokawa, Toshiyuki Kita, Hiroki Shirasaki, Kazuyoshi Watanabe, Hideharu Kimura, Kazuo Kasahara
- Organizer
  2014 ASCO Annual Meeting
- Place of Presentation
  Mccormick Place Chicago,USA
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-26430159

1. Kasahara Kazuo (30272967)

# of Collaborated Projects: 5 results

# of Collaborated Products: 14 results
2. Sone Takashi (30420334)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
3. KUDO Masatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. KITANO Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. ARAO Tokuzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 安居幸一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 西尾和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 長尾俊孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Hideharu 木村 英晴

KIMURA Hideharu 木村 英晴

Research Projects

Research Products

Co-Researchers

Immunogenic cell death by cytotoxic agents

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Establishment of monitoring method using cfDNA gene mutation profile in patients with malignant tumorsPrincipal Investigator

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Personalized therapy targeting Met gene in lung cancer

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Identification of Novel Treatment Targets and Biomarkers for Small-Cell Lung Cancer by Circulating Tumor Cell AnalysisPrincipal Investigator

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Regulation of Topisomerase I activity by cMet in lung cancer

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Analysis of predictive biomarker of Erlotinib to non-small cell lung cancer without EGFR mutation

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VEGFR2 tyrosine kinase inhibitor (VEGFR2-TKI)-resistant cancer tissue from a cancer-bearing mouse modelPrincipal Investigator

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Detection of tumor-derived mutations in circulating DNAPrincipal Investigator

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[Book] 遺伝子変異検査. 「新臨床腫瘍学-がん薬物療法専門医のために-」(NPO法人日本臨床腫瘍学会編)2009

Author(s)

Publisher

Data Source

[Book] 「新臨床腫瘍学-がん薬物療法専門医のために-」(NPO法人日本臨床腫瘍学会編)2009

Author(s)

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Data Source

[Book] 遺伝子変異検査.「新臨床腫瘍学(改訂第 3版)」(日本臨床腫瘍学会 編)

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[Journal Article] Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis2021

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[Journal Article] Late-onset programmed cell death protein-1 inhibitor-induced pneumonitis after cessation of nivolumab or pembrolizumab in patients with advanced non-small cell lung cancer: a case series2021

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[Journal Article] Successful Treatment of Advanced Thymic Carcinoma with Carboplatin plus <b><i>nab</i></b>-Paclitaxel and Maintenance Monotherapy with <b><i>nab</i></b>-Paclitaxel: Two Case Reports2020

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Kimura Hideharu 木村英晴

KIMURA Hideharu 木村英晴

[Book] 遺伝子変異検査.「新臨床腫瘍学(改訂第 3版)」(日本臨床腫瘍学会編)