Kitaguchi Yoshiaki 北口良晃

Researcher Number	40447751
Other IDs	https://orcid.org/0000-0002-3922-4082
Affiliation (Current)	2024: 信州大学, 学術研究院医学系(医学部附属病院), 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 信州大学, 学術研究院医学系(医学部附属病院), 講師 2016 – 2023: 信州大学, 医学部附属病院, 助教(診療)
Review Section/Research Field	Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine
Keywords	Except Principal Investigator 肺気腫 / 第3群肺高血圧症 / ラット / 診断 / 低酸素 / VEGF受容体阻害薬 / 遺伝子ライブラリ / バイオマーカー / Sphingosine 1-phosphate / スフィンゴシンキナーゼ１ … More / 動物モデル / 第1群肺高血圧症 / 第３群肺高血圧症 / 組織貫通型ホーミングペプチド / 選択的肺血管拡張薬 / 末梢肺野小結節 / 屈曲可能ガイドシース / 気管支鏡 / 超細径内視鏡 / 動物実験 / 細径内視鏡 / アブレーション / 治療 / 早期肺癌 / 呼吸リハビリテーション / 過去吸 / 呼吸困難感 / 運動負荷 / SGRQ-C / QOL / 運動耐容能 / 肺過膨張 / 最大吸気量 / 過呼吸 / 動的肺過膨張 / 慢性閉塞性肺疾患 / タバコ抽出液 / 血管内皮成長因子受容体阻害薬 / 3群肺高血圧症 Less

Investigation of biomarker in group 3 pulmonary hypertension
- Principal Investigator
  
  花岡正幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Shinshu University
スフィンゴシン１-フォスフェートによる第3群肺高血圧モデルラットの病態修飾
- Principal Investigator
  
  安尾将法
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Shinshu University
Effects of the treatment with respiratory rehabilitation on the lung dynamic hyperinflation in COPD
- Principal Investigator
  
  Fujimoto Keisaku
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Shinshu University
Diagnosis of small peripheral pulmonary lesion by using novel ultra-thin bronchoscope and bendable guide sheath
- Principal Investigator
  
  安尾将法
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Shinshu University
Establishment of strategy of treatment for the group 3 pulmonary hypertension in a novel animal model
- Principal Investigator
  
  Hanaoka Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Shinshu University
Establishment of a novel model of group 3 pulmonary hypertension induced by SU5416/hypoxia in rats
- Principal Investigator
  
  HANAOKA Masayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Shinshu University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice2021
- Author(s)
  Morichika Daisuke、Taniguchi Akihiko、Oda Naohiro、Fujii Utako、Senoo Satoru、Itano Junko、Kanehiro Arihiko、Kitaguchi Yoshiaki、Yasuo Masanori、Hanaoka Masayuki、Satoh Takashi、Akira Shizuo、Kiura Katsuyuki、Maeda Yoshinobu、Miyahara Nobuaki
- Journal Title
  
  Respiratory Research
  
  Volume: 22 Issue: 1 Pages: 1-12
- DOI
  10.1186/s12931-021-01705-z
- NAID
  120007098538
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08647
[Journal Article] Clinical characteristics of non-idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung diseases2021
- Author(s)
  Komatsu Masamichi、Yamamoto Hiroshi、Kitaguchi Yoshiaki、Kawakami Satoshi、Matsushita Mina、Uehara Takeshi、Kinjo Takumi、Wada Yosuke、Ichiyama Takashi、Urushihata Kazuhisa、Ushiki Atsuhito、Yasuo Masanori、Hanaoka Masayuki
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 13 Pages: e25322-e25322
- DOI
  10.1097/md.0000000000025322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08647
[Journal Article] The usefulness of a combination of age, body mass index, and blood urea nitrogen as prognostic factors in predicting oxygen requirements in patients with coronavirus disease 20192021
- Author(s)
  Goto Norihiko、Wada Yosuke、Ikuyama Yuichi、Akahane Jumpei、Kosaka Makoto、Ushiki Atsuhito、Kitaguchi Yoshiaki、Yasuo Masanori、Yamamoto Hiroshi、Matsuo Akemi、Hachiya Tsutomu、Ideura Gen、Yamazaki Yoshitaka、Hanaoka Masayuki
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 12 Pages: 1706-1712
- DOI
  10.1016/j.jiac.2021.08.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08647
[Journal Article] Automated Diseased Lung Volume Percentage Calculation in Quantitative CT Evaluation of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis2021
- Author(s)
  Kitaguchi Yoshiaki、Fujimoto Keisaku、Droma Yunden、Yasuo Masanori、Wada Yosuke、Ueno Fumika、Kinjo Takumi、Kawakami Satoshi、Fukushima Kiyoyasu、Hanaoka Masayuki
- Journal Title
  
  Journal of Computer Assisted Tomography
  
  Volume: 45 Issue: 4 Pages: 649-658
- DOI
  10.1097/rct.0000000000001182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08599, KAKENHI-PROJECT-19K08647
[Journal Article] Differences Between Central Airway Obstruction and Chronic Obstructive Pulmonary Disease Detected with the Forced Oscillation Technique2020
- Author(s)
  Yasuo Masanori、Kitaguchi Yoshiaki、Tokoro Yayoi、Kosaka Makoto、Wada Yosuke、Kinjo Takumi、Ushiki Atsuhito、Yamamoto Hiroshi、Hanaoka Masayuki
- Journal Title
  
  International Journal of Chronic Obstructive Pulmonary Disease
  
  Volume: Volume 15 Pages: 1425-1434
- DOI
  10.2147/copd.s246126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08647, KAKENHI-PROJECT-19H03666
[Journal Article] The Gly82Ser mutation in AGER contributes to pathogenesis of pulmonary fibrosis in combined pulmonary fibrosis and emphysema (CPFE) in Japanese patients2020
- Author(s)
  Kinjo T, Kitaguchi Y, Droma Y, Yasuo M, Wada Y, Ueno F, Ota M, Hanaoka M
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 12811-12811
- DOI
  10.1038/s41598-020-69184-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03666
[Journal Article] The Interstitial Lung Disease-Gender-Age-Physiology Index Can Predict the Prognosis in Surgically Resected Patients with Interstitial Lung Disease and Concomitant Lung Cancer2020
- Author(s)
  Ueno Fumika、Kitaguchi Yoshiaki、Shiina Takayuki、Asaka Shiho、Yasuo Masanori、Wada Yosuke、Kinjo Takumi、Yoshizawa Akihiko、Hanaoka Masayuki
- Journal Title
  
  Respiration
  
  Volume: 99 Issue: 1 Pages: 9-18
- DOI
  10.1159/000502849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08647
[Journal Article] Probe-based optical fiberscopy for the direct observation of peripheral pulmonary lesions2019
- Author(s)
  Kosaka Makoto、Yasuo Masanori、Kinota Fumiya、Machida Ryosuke、Kitaguchi Yoshiaki、Ushiki Atsuhito、Yamamoto Hiroshi、Uehara Takeshi、Hamanaka Kazutoshi、Kawakami Satoshi、Hanaoka Masayuki
- Journal Title
  
  Respiratory Investigation
  
  Volume: 57 Issue: 5 Pages: 481-489
- DOI
  10.1016/j.resinv.2019.06.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08647
[Presentation] 第3群肺高血圧症動物モデルへの肺血管拡張薬とCAR併用投与の効果2022
- Author(s)
  後藤　憲彦, 和田　洋典, 北口　良晃, 安尾　将法, 花岡　正幸
- Organizer
  第7回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08255
[Presentation] Combination of CAR(CARSKNKDC) peptide with sildenafil in the treatment of pulmonary hypertension associated with emphysema induced by SU5416 in rats2022
- Author(s)
  Norihiko Goto, Yosuke Wada, Yoshiaki Kitaguchi, Masanori Yasuo, Masayuki Hanaoka
- Organizer
  26th Congress of the Asia Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08255
[Presentation] SU5416/慢性低酸素曝露肺高血圧症ラットモデルへのシルデナフィル投与におけるホーミングペプチド併用の効果2022
- Author(s)
  後藤　憲彦, 和田　洋典, 北口　良晃, 安尾　将法, 花岡　正幸
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K08255
[Presentation] 気腫合併肺線維症患者におけるCTの客観的指標の有用性について2021
- Author(s)
  北口良晃，中村優志，金城　匠，安尾将法，和田洋典，上野史香，後藤憲彦，福島喜代康，花岡正幸.
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08647
[Presentation] Activation of cleaved caspase 3 in young rats of emphysema with pulmonary hypertension induced by SU54162021
- Author(s)
  Norihiko Goto, Yosuke Wada, Yoshiaki Kitaguchi, Masanori Yasuo, Masayuki Hanaoka
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03666
[Presentation] SU5416によって誘発された肺高血圧症を伴う肺気腫の若いラットにおける切断されたカスパーゼ-3の活性化2021
- Author(s)
  後藤憲彦，和田洋典，北口良晃，安尾将法，花岡正幸
- Organizer
  第25回アジア太平洋呼吸器学会学術集会(25th. APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08647
[Presentation] 胸部CTにおいて客観的かつ同時に肺気腫および間質性肺炎を解析する有用性．2020
- Author(s)
  北口良晃、藤本圭作、安尾将法、和田洋典、上野史香、福島喜代康、花岡正幸。
- Organizer
  第60回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08599
[Presentation] SU5416/低酸素暴露PHラットモデルにおけるシルデナフィル早期投与の効果2020
- Author(s)
  後藤憲彦，和田洋典，北口良晃，安尾将法，花岡正幸
- Organizer
  第5回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03666
[Presentation] SU5416投与肺気腫肺高血圧ラットモデルにおける肺病変と週齢との関連2020
- Author(s)
  後藤憲彦, 和田洋典, 北口良晃, 安尾将法, 立石一成, 漆畑一寿, 牛木淳人, 山本　洋, 花岡正幸
- Organizer
  第60回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08647
[Presentation] 気管狭窄と主気管支狭窄における呼吸インピーダンス、呼吸機能の比較2019
- Author(s)
  安尾将法、北口良晃、和田洋典、小坂充、金城匠、立石一成、漆畑一寿、牛木淳人、山本洋、花岡正幸
- Organizer
  第59回日本呼吸器内視鏡学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08647
[Presentation] III群肺高血圧症モデルを使用した肺高血圧症の病態解明2019
- Author(s)
  安尾将法, 和田洋典, 北口良晃, 花岡正幸
- Organizer
  第59回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03666
[Presentation] Reduction of antioxidant activity in rats of emphysema with pulmonary hypertension induced by SU5416/Hypoxia: Potential roles of vascular endothelial growth factor2019
- Author(s)
  Wada Y, Kitaguchi Y, Yasuo M, Hanaoka M
- Organizer
  Asian Pacific Society of Respirology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03666
[Presentation] III群肺高血圧は本当にIII群か？　III群肺高血圧症モデルを使用した肺高血圧症の病態解明2019
- Author(s)
  安尾将法, 和田洋典, 北口良晃, 花岡正幸
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09532
[Presentation] SU5416/慢性低酸素曝露3群肺高血圧ラットによる炎症性メディエーターの検討2018
- Author(s)
  和田洋典, 北口良晃, 安尾将法, 花岡正幸
- Organizer
  第3回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09532
[Presentation] Establishment of a novel model of group 3 pulmonary hypertension induced by SU5416/hypoxia in rats2018
- Author(s)
  Wada Y, Kitaguchi Y, Yasuo M, Hanaoka M
- Organizer
  6th World Symposium on Pulmonary Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09532
[Presentation] Antioxidant activity of a SU5416/hypoxia-induced emphysema and pulmonary hypertension model in rats2018
- Author(s)
  Wada Y, Kitaguchi Y, Yasuo M, Hanaoka M
- Organizer
  ISMM Word Congress on Mountain Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09532
[Presentation] Establishment of a novel model of group 3 pulmonary hypertension induced by SU5416/hypoxia in rats2018
- Author(s)
  Yosuke Wada, Yoshiaki Kitaguchi, Masanori Yasuo, Masayuki Hanaoka
- Organizer
  6th World Symposium on Pulmonary Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09532
[Presentation] SU5416/低酸素曝露による第3群肺高血圧症ラットモデルの確立2018
- Author(s)
  和田洋典, 北口良晃, 安尾将法, 小林信光, 立石一成, 漆畑一寿, 牛木淳人, 山本洋,花岡正幸
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09532

1. HANAOKA Masayuki (20334899)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
2. 安尾将法 (20402117)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
3. 和田洋典 (80848739)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. Fujimoto Keisaku (70242691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 川内翔平 (80827965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 曽根原圭 (40647260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YUNDEN Droma

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kitaguchi Yoshiaki 北口 良晃

Research Projects

Research Products

Co-Researchers

Investigation of biomarker in group 3 pulmonary hypertension

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

スフィンゴシン１-フォスフェートによる第3群肺高血圧モデルラットの病態修飾

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of the treatment with respiratory rehabilitation on the lung dynamic hyperinflation in COPD

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diagnosis of small peripheral pulmonary lesion by using novel ultra-thin bronchoscope and bendable guide sheath

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of strategy of treatment for the group 3 pulmonary hypertension in a novel animal model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a novel model of group 3 pulmonary hypertension induced by SU5416/hypoxia in rats

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Clinical characteristics of non-idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung diseases2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The usefulness of a combination of age, body mass index, and blood urea nitrogen as prognostic factors in predicting oxygen requirements in patients with coronavirus disease 20192021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated Diseased Lung Volume Percentage Calculation in Quantitative CT Evaluation of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differences Between Central Airway Obstruction and Chronic Obstructive Pulmonary Disease Detected with the Forced Oscillation Technique2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Gly82Ser mutation in AGER contributes to pathogenesis of pulmonary fibrosis in combined pulmonary fibrosis and emphysema (CPFE) in Japanese patients2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Interstitial Lung Disease-Gender-Age-Physiology Index Can Predict the Prognosis in Surgically Resected Patients with Interstitial Lung Disease and Concomitant Lung Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Probe-based optical fiberscopy for the direct observation of peripheral pulmonary lesions2019

Author(s)

Journal Title

DOI

Kitaguchi Yoshiaki 北口良晃

[Presentation] SU5416によって誘発された肺高血圧症を伴う肺気腫の若いラットにおける切断されたカスパーゼ-3の活性化2021

[Presentation] III群肺高血圧は本当にIII群か？　III群肺高血圧症モデルを使用した肺高血圧症の病態解明2019