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SAKAGUCHI ISAO  坂口 勲

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SAKAGUCHI Isao  坂口 勲

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Researcher Number 40448527
Other IDs
Affiliation (based on the past Project Information) *help 2017 – 2018: 熊本大学, 医学部附属病院, 講師
2013 – 2016: 熊本大学, 医学部附属病院, 助教
2009 – 2011: Kumamoto University, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
Keywords
Principal Investigator
子宮内膜症 / 卵巣明細胞腺癌 / 血栓塞栓症 / ARID1A / 卵巣明細胞癌 / 静脈血栓塞栓症 / 明細胞癌 / 卵巣癌 / 黄体ホルモン療法 / Cre-loxPシステム … More / 遺伝子改変マウス / 黄体ホルモン / PTEN遺伝子 / 子宮内膜癌 … More
Except Principal Investigator
卵巣癌治療 / 卵巣表層上皮 / 癌幹細胞 / 卵巣癌 / マクロファージ / 癌幹細胞ニッチ / 卵巣癌モデル / 上皮性卵巣癌 / CD44 Less
  • Research Projects

    (4 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (6 People)
  •  Elucidation of interactions between cancer stem cells and their niche: Dual-targeted therapy in ovarian cancer patients

    • Principal Investigator
      Katabuchi Hidetaka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  The development of the novel strategy for venous thromboembolism in ovarian clear cell carcinomasPrincipal Investigator

    • Principal Investigator
      SAKAGUCHI ISAO
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  Novel therapeutic strategy targeting ovarian cancer stem cells and their niche

    • Principal Investigator
      Katabuchi Hidetaka
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  Development of mice model for inquiry into therapeutic targets : an anticancer effect of dienogest on endometrial neoplasmPrincipal Investigator

    • Principal Investigator
      SAKAGUCHI Isao
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University

All 2018 2017 2016 2015 2011 2009 Other

All Journal Article Presentation

  • [Journal Article] The impact of EpCAM expression on response to chemotherapy and clinical outcomes in patients with epithelial ovarian cancer.2017

    • Author(s)
      Tayama S, Motohara T, Narantuya D, Li C, Fujimoto K, Sakaguchi I, Tashiro H, Saya H, Nagano O, Katabuchi H
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 27 Pages: 44312-44325

    • DOI

      10.18632/oncotarget.17871

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11145, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-16H05473
  • [Journal Article] CD44 variant 6 as a predictive biomarker for distant metastasis in patients with epithelial ovarian cancer.2016

    • Author(s)
      11.Motohara T, Fujimoto K, Tayama S, Narantuya D, Guo J, Sakaguchi I, Tashiro H, Katabuchi H.
    • Journal Title

      Epub ahead of print

      Volume: Epub ahead of print

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293344
  • [Journal Article] CD44 Variant 6 as a Predictive Biomarker for Distant Metastasis in Patients With Epithelial Ovarian Cancer.2016

    • Author(s)
      Motohara T, Fujimoto K, Tayama S, Narantuya D, Sakaguchi I, Tashiro H, Katabuchi H.
    • Journal Title

      Obstet Gynecol.

      Volume: 127 Issue: 6 Pages: 1003-11

    • DOI

      10.1097/aog.0000000000001420

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05473, KAKENHI-PROJECT-16K11145
  • [Journal Article] High-dose oral tegafur-uracil maintenance therapy in patients with uterine cervical cancer.2015

    • Author(s)
      Sakaguchi I, Motohara T, Saito F, Takaishi K, Fukumatsu Y, Tohya T, Shibata S, Mimori H, Tashiro H, Katabuchi H.
    • Journal Title

      J Gynecol Oncol.

      Volume: 26 Pages: 193-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10722
  • [Journal Article] Low-grade漿液性腺癌の臨床病理・ゲノムと治療法.2015

    • Author(s)
      本原 剛志, 坂口 勲, 片渕秀隆.
    • Journal Title

      臨婦産.

      Volume: 69 Pages: 118-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293344
  • [Journal Article] CD44 variant 6 is correlated with peritoneal dissemination and poor prognosis in patients with advanced epithelial ovarian cancer.2015

    • Author(s)
      Tjhay F, Motohara T, Tayama S, Narantuya D, Fujimoto K, Guo J, Sakaguchi I, Honda R, Tashiro H, Katabuchi H.
    • Journal Title

      Cancer Sci

      Volume: 106 Issue: 10 Pages: 1421-1428

    • DOI

      10.1111/cas.12765

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20151, KAKENHI-PROJECT-25293344
  • [Journal Article] CD44 variant 6 is correlated with peritoneal dissemination and poor prognosis in patients with advanced epithelial ovarian cancer.2015

    • Author(s)
      Tjhay F, Motohara T, Tayama S, Narantuya D, Fujimoto K, Guo J, Sakaguchi I, Honda R, Tashiro H, Katabuchi H.
    • Journal Title

      Cancer Sci. 2015 Oct;106(10):1421-8.

      Volume: 106 Pages: 1421-1428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10722
  • [Journal Article] 若年発症子宮内位膜癌の病態におけるプロラクチンの臨床的意義2011

    • Author(s)
      齋藤文誉、田代浩徳、松尾勇児、坂口勲、宮原陽、本田律生、片渕秀隆
    • Journal Title

      日本婦人科腫瘍学会雑誌

      Volume: 29 Pages: 697-703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592138
  • [Journal Article] 子宮肉腫の妊孕能温存治療2009

    • Author(s)
      片渕秀隆, 坂口勲, 田代浩徳
    • Journal Title

      産婦人科の実際 58

      Pages: 365-372

    • Data Source
      KAKENHI-PROJECT-21592138
  • [Journal Article] 子宮肉腫の妊孕能温存治療2009

    • Author(s)
      片渕秀隆、坂口勲、田代浩徳
    • Journal Title

      産婦人科の実際

      Volume: 58 Pages: 365-373

    • Data Source
      KAKENHI-PROJECT-21592138
  • [Presentation] Clinical comparisons of treatment strategies for advanced endometrial cancer in different countries2018

    • Author(s)
      Isao Sakaguchi
    • Organizer
      The 6th International Conference of Federation of Asian Clinical Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10722
  • [Presentation] CD44 variant 6 is associated with peritoneal metastasis and poor prognosis in advanced ovarian cancer patients.2015

    • Author(s)
      Takeshi Motohara, Shingo Tayama, Isao Sakaguchi, Hironori Tashiro, Hidetaka Katabuchi.
    • Organizer
      The 74th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293344
  • [Presentation] Survival impact of wide resection of the pelvic peritoneum in patients with epithelial ovarian cancer:Towards the development of novel surgical strategies for the removal of ovarian cancer stem cells and their niche

    • Author(s)
      Motohara T., Tayama S., Saito F., Tjhay F., Takaishi K., Sakaguchi I., Tashiro H., Katabuchi K.
    • Organizer
      The 4th Asan-Kumamoto Joint Symposium
    • Place of Presentation
      阿蘇リゾートグランヴィリオホテル、Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-25293344
  • [Presentation] 卵巣癌におけるEpCAM陽性細胞は抗アポトーシス作用を介した抗がん剤治療抵抗性を有する

    • Author(s)
      田山 親吾、本原 剛志、坂口 勲、田代 浩徳、片渕 秀隆
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-24 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25293344
  • 1.  KATABUCHI Hidetaka (90224451)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 13 results
  • 2.  TASHIRO Hironori (70304996)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 3.  SAITO Fumitaka (20555742)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  MOTOHARA TAKESHI (10457591)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  TAKAISHI KIYOMI (00601303)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  Tsuboki Junko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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