Wada Shun-ici 和田俊一

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Wada Shun-ichi 和田俊一

WADA Syunichi 和田俊一

WADA Shun-ichi 和田俊一

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Researcher Number	40450233
Affiliation (Current)	2025: 公益財団法人微生物化学研究会, 微生物化学研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 公益財団法人微生物化学研究会, 微生物化学研究所, 主任研究員 2020 – 2022: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員 2015 – 2017: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員 2016: 公益財団法人微生物化学研究会, 微生物化学研究所, 上級研究員 2012: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究員 2011: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 38020:Applied microbiology-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Natural medicines / Clinical oncology Except Principal Investigator Applied microbiology
Keywords	Principal Investigator トレハロース / 放線菌 / trehalose / レンツトレハロース / Trehalosamine / lentztrehalose / 合併症 / 天然物 / 溶血液 / 微生物 … More / 食品植物 / 抗酸化物質 / trehalosamine / トレハロサミン / くも膜下出血 / オートファジー / アルツハイマー病 / 神経変性疾患 / ペプチド / がん / 抗腫瘍物質 / 細胞毒性 / 培養細胞 / 代謝産物 / 水圏微生物 / ケミカルバイオロジー / 抗がん物質探索 … More Except Principal Investigator 抗生物質 / MALDI TOF MS / 代謝物解析 / 新規抗生物質 / Streptomyces / Nonomuraea / 深海由来放線菌 / 代謝物 / enediyne / シデロフォア / 新規代謝物 / MALDI-TOF MS / 分類 / Micromonospora / 放線菌 / 深海底泥 Less

Search of trehalosamines and their functions in actinomycetesPrincipal Investigator
- Principal Investigator
  
  和田俊一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Microbial Chemistry Research Foundation
Search and development of drugs for prevention and treatment of subarachnoid hemorrhage complications from natural products.Principal Investigator
- Principal Investigator
  
  Wada Shun-ichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
Mechanism of lentztrehalose-induced autophagy; its application for the treatment of neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  WADA Shun-ichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Microbial Chemistry Research Foundation
Study on biased species of actinomycetes in deep sea and its metabolites
- Principal Investigator
  
  IGARASHI Masayuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Microbial Chemistry Research Foundation
Search for antitumor compounds from symbiotic or parasitic microbes in aquatic multicellular organismsPrincipal Investigator
- Principal Investigator
  
  WADA Shun-ichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Microbial Chemistry Research Foundation

All 2022 2021 2017 2016 2015 2013

All Journal Article Presentation Patent

[Journal Article] Rediscovery of 4‐Trehalosamine as a Biologically Stable, Mass‐Producible, and Chemically Modifiable Trehalose Analog2022
- Author(s)
  Wada Shun‐ichi、Arimura Honami、Nagayoshi Miho、Sawa Ryuichi、Kubota Yumiko、Matoba Kazuaki、Hayashi Chigusa、Shibuya Yuko、Hatano Masaki、Takehana Yasuhiro、Ohba Shun‐ichi、Kobayashi Yoshihiko、Watanabe Takumi、Shibasaki Masakatsu、Igarashi Masayuki
- Journal Title
  
  Advanced Biology
  
  Volume: Early View Issue: 6 Pages: 2101309-2101309
- DOI
  10.1002/adbi.202101309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07123
[Journal Article] ATP Depletion Assay Led to the Isolation of New 36-Membered Polyol Macrolides Deplelides A and B from Streptomyces sp. MM581-NF152017
- Author(s)
  Toshifumi Takeuchi , Masaki Hatano, Maya Umekita, Chigusa Hayashi, Shun-ichi Wada, Miho Nagayoshi, Ryuichi Sawa, Yumiko Kubota, Manabu Kawada, Masayuki Igarashi, Masakatsu Shibasaki
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 16 Pages: 4207-7210
- DOI
  10.1021/acs.orglett.7b01807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13261, KAKENHI-PROJECT-15K06888, KAKENHI-PROJECT-15K08013
[Journal Article] Structures and biological activities of novel 4’-acetylated analogs of chrysomycins A and B.2017
- Author(s)
  Wada, S., Sawa, R., Iwanami, F., Nsgayoshi, M., Kubota, Y., Iijima, K., Hayashi, C., Shibuya, Y., Hatano, M., Igarashi, M., Kawada, M.
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 11 Pages: 1078-1082
- DOI
  10.1038/ja.2017.99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06888, KAKENHI-PROJECT-15K08013
[Journal Article] Novel approaches for identification of anti-tumor drugs and new bioactive compounds2017
- Author(s)
  Kawada Manabu、Atsumi Sonoko、Wada Shun-ichi、Sakamoto Shuichi
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 71 Issue: 1 Pages: 39-44
- DOI
  10.1038/ja.2017.97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08013
[Journal Article] Valgamicin C, a novel cyclic depsipeptide containing the unusual amino acid cleonine, and related valgamicins A, T and V produced by Amycolatopsis sp. ML1-hF42017
- Author(s)
  Hashizume Hideki、Iijima Kiyoko、Yamashita Kazuma、Kimura Tomoyuki、Wada Shun-ichi、Sawa Ryuichi、Igarashi Masayuki
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 71 Issue: 1 Pages: 129-134
- DOI
  10.1038/ja.2017.135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08013
[Journal Article] Stability and Bioavailability of Lentztrehaloses A, B, and C as Replacements for Trehalose.2016
- Author(s)
  Wada S, Sawa R, Ohba S, Hayashi C, Umekita M, Shibuya Y, Iijima K, Iwanami F, Igarashi M.
- Journal Title
  
  J Agric Food Chem.
  
  Volume: 64 Issue: 38 Pages: 7121-7126
- DOI
  10.1021/acs.jafc.6b02782
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450107, KAKENHI-PROJECT-15K08013
[Journal Article] Synthesis and Determination of Absolute Configuration of Lentztrehalose A2015
- Author(s)
  Zhang M, Wada S, Amemiya F, Watanabe T, Shibasaki M.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 63 Issue: 11 Pages: 961-966
- DOI
  10.1248/cpb.c15-00600
- NAID
  130005105723
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08013
[Journal Article] Novel autophagy inducers lentztrehaloses A, B and C.2015
- Author(s)
  Wada S, Kubota Y, Sawa R, Umekita M, Hatano M, Ohba S, Hayashi C, Igarashi M, Nomoto A.
- Journal Title
  
  J Antibiot
  
  Volume: 68 Issue: 8 Pages: 521-529
- DOI
  10.1038/ja.2015.23
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08013
[Patent] 新規化合物、その用途、及びその製造方法、並びに、化合物含有組成物、４－トレハロサミンの製造方法、及び微生物2021
- Inventor(s)
  和田俊一、有村帆波美、五十嵐雅之、永吉美穂、他
- Industrial Property Rights Holder
  公益財団法人微生物化学研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-144962
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K07123
[Patent] レンツトレハロースAの製造方法、並びに前記製造方法に有用な化合物及びその製造方法2015
- Inventor(s)
  渡邊匠、和田俊一、五十嵐雅之、張明
- Industrial Property Rights Holder
  公益財団法人微生物化学研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K08013
[Patent] 新規化合物レンツトレハロース、その製造方法、及びその用途、並びに、新規微生物2013
- Inventor(s)
  和田俊一、大庭俊一、染野哲也、波多野和樹
- Industrial Property Rights Holder
  公益財団法人微生物化学研究会
- Industrial Property Number
  2013-110521
- Filing Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23701108
[Presentation] 生物学的安定性が高く、大量生産可能で、化学修飾しやすい trehalose 類縁体としての 4-trehalosamine の再発見2022
- Author(s)
  和田俊一、澤竜一、久保田由美子、大庭俊一、吉田温子、松波さくら、五十嵐雅之
- Organizer
  日本応用糖質科学会2022年度大会
- Data Source
  KAKENHI-PROJECT-20K07123
[Presentation] 希少放線菌 Amycolatopsis sp. ML1-hF4株の生産する新規化合物 pargamicins A,B,C,Dの構造解析および生物活性2017
- Author(s)
  橋爪秀樹、山下和真、久保田由美子、林千草、和田俊一、原田滋子、澤竜一、五十嵐雅之
- Organizer
  2017年度　日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-15K08013
[Presentation] 新規4'-acetyl-chrysomycin A, Bの構造と生物活性2017
- Author(s)
  和田俊一、澤竜一、岩波史樹、永吉美穂、久保田由美子、飯島希昌子、林千草、渋谷優子、波多野和樹、五十嵐雅之、川田学
- Organizer
  2017年度　日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-15K08013
[Presentation] Lentzea 属放線菌由来新規trehalose 類縁体lentztrehalose 類の構造と生物活性2017
- Author(s)
  和田俊一，澤　竜一，大庭俊一，波多野和樹，染野哲也，久保田由美子，梅北まや，林　千草，飯島希昌子，渋谷優子，川田　学，五十嵐雅之
- Organizer
  日本農芸化学会　2017 年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K08013
[Presentation] 希少放線菌 Amycolatopsis sp. ML1-hF4 株の生産する異常アミノ酸 cleonine 含有新規化合物 valgamicin C および新規類縁体の構造および生物活性2016
- Author(s)
  橋爪秀樹, 山下和真, 飯島希昌子, 木村智之, 渋谷優子, 和田俊一, 澤竜一, 五十嵐雅之
- Organizer
  2016 年度日本放線菌学会大会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K08013
[Presentation] Lentzea 属放線菌由来lentztrehalose 類のtrehalose 改良品としての安定性評価2016
- Author(s)
  和田俊一, 澤竜一, 大庭俊一, 林千草, 梅北まや, 渋谷優子, 飯島希昌子, 五十嵐雅之
- Organizer
  2016 年度日本放線菌学会大会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-15K08013
[Presentation] Lentzea 属放線菌由来 lentztrehalose 類の trehalose 改良品としての安定性評価2016
- Author(s)
  和田俊一、澤竜一、大庭俊一、林千草、梅北まや、渋谷優子、飯島希昌子、五十嵐雅之
- Organizer
  第31回日本放線菌学会大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-26450107
[Presentation] Lentzea属放線菌由来trehalose類縁体lentztrehalose類の構造と生物活性2015
- Author(s)
  和田俊一, 澤竜一, 大庭俊一, 染野哲也, 久保田由美子, 波多野和樹, 梅北まや, 張明, 渡辺匠, 林千草, 川田学, 五十嵐雅之, 柴﨑正勝
- Organizer
  第30回　日本放線菌学会大会
- Place of Presentation
  富山国際会議場　(富山)
- Year and Date
  2015-09-08
- Data Source
  KAKENHI-PROJECT-15K08013

1. SAWA Ryuichi (50235454)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. IGARASHI Masayuki (40260137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. HATANO Masaki (40414106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KATO Chiaki (90360750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 奈良岡征都 (10455751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 竹内倫文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 川田学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wada Shun-ici 和田 俊一

Wada Shun-ichi 和田 俊一

WADA Syunichi 和田 俊一

WADA Shun-ichi 和田 俊一

Research Projects

Research Products

Co-Researchers

Search of trehalosamines and their functions in actinomycetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search and development of drugs for prevention and treatment of subarachnoid hemorrhage complications from natural products.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of lentztrehalose-induced autophagy; its application for the treatment of neurodegenerative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on biased species of actinomycetes in deep sea and its metabolites

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for antitumor compounds from symbiotic or parasitic microbes in aquatic multicellular organismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rediscovery of 4‐Trehalosamine as a Biologically Stable, Mass‐Producible, and Chemically Modifiable Trehalose Analog2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ATP Depletion Assay Led to the Isolation of New 36-Membered Polyol Macrolides Deplelides A and B from Streptomyces sp. MM581-NF152017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structures and biological activities of novel 4’-acetylated analogs of chrysomycins A and B.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel approaches for identification of anti-tumor drugs and new bioactive compounds2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Valgamicin C, a novel cyclic depsipeptide containing the unusual amino acid cleonine, and related valgamicins A, T and V produced by Amycolatopsis sp. ML1-hF42017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stability and Bioavailability of Lentztrehaloses A, B, and C as Replacements for Trehalose.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and Determination of Absolute Configuration of Lentztrehalose A2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Novel autophagy inducers lentztrehaloses A, B and C.2015

Author(s)

Journal Title

DOI

Data Source

Wada Shun-ici 和田俊一

Wada Shun-ichi 和田俊一

WADA Syunichi 和田俊一

WADA Shun-ichi 和田俊一