KANZAWA Noriyuki 神澤範行

Researcher Number	40452461
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2016: 大阪大学, 微生物病研究所, 特任助教 2014: 大阪大学, 微生物病研究所, 特任助教(常勤) 2011 – 2013: 大阪大学, 微生物病研究所, 特任助教
Review Section/Research Field	Principal Investigator Pathological medical chemistry Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator GPIアンカー / ペルオキシソーム病 / 脂質リモデリング / アルキル脂質 / アルキルリン脂質 / リン脂質 / ＧＰＩアンカー / 先天性代謝異常 / グリコシルホスファチジルアンカー / アルキルアシル型リン脂質 … More / Zellweger症候群 / RCDP / Zellweger 症候群 / 肢根型点状軟骨異形成症 / GPI アンカー … More Except Principal Investigator ホメオスターシス / 層板顆粒 / ゴルジ / ホメオスタシス / GPHR / 膜コンタクト部位 / 輸送 / 糖鎖修飾 / コレステロール / pH / ゴルジ装置 Less

GPIアンカーの構造から解明するペルオキシソーム病の病態と発症メカニズムPrincipal Investigator
- Principal Investigator
  
  神澤範行
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Analysis of peroxisomal disorders from the structure of GPI anchorsPrincipal Investigator
- Principal Investigator
  
  KANZAWA Noriyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Study of pH homeostasis in acidic organelles
- Principal Investigator
  
  MAEDA YUSUKE
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Abnormality of the involvement of glycosylphosphatidylinositol anchor in a peroxisomal disorder.Principal Investigator
- Principal Investigator
  
  KANZAWA Noriyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University

All 2016 2015 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 生体の科学「細胞の分子構造と機能 -核以外の細胞小器官- GPI アンカーのリモデリングにおけるペルオキシソームの役割とその異常」2012
- Author(s)
  神澤範行, 木下タロウ
- Data Source
  KAKENHI-PROJECT-23790365
[Journal Article] A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.2016
- Author(s)
  Lee GH, Fujita M, Takaoka K, Murakami Y, Fujihara Y, Kanzawa N, Murakami KI, Kajikawa E, Takada Y, Saito K, Ikawa M, Hamada H, Maeda Y, Kinoshita T.
- Journal Title
  
  J Cell Biol
  
  Volume: 215 Issue: 5 Pages: 705-718
- DOI
  10.1083/jcb.201605121
- NAID
  120006957406
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15K08303, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001
[Journal Article] Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability2013
- Author(s)
  Hirata, T., M. Fujita, N. Kanzawa, Y. Murakami, Y. Maeda and T. Kinoshita
- Journal Title
  
  J. Bio chem
  
  Volume: 154 Issue: 3 Pages: 257-264
- DOI
  10.1093/jb/mvt045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23687017, KAKENHI-PROJECT-25860238
[Journal Article] Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia-mental retardation syndrome2012
- Author(s)
  Murakami, Y., N. Kanzawa, K. Saito, P. M. Krawitz, S. Mundlos, P. N. Robinson, A. Karadimitris, Y. Maeda and T. Kinoshita
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 9 Pages: 6318-6325
- DOI
  10.1074/jbc.m111.331090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23590363, KAKENHI-PROJECT-23790365
[Journal Article] Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome and rhizomelic chondrodysplasia punctata2012
- Author(s)
  Kanzawa, N., et al.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 53 Issue: 4 Pages: 653-663
- DOI
  10.1194/jlr.m021204
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058011, KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-21591318, KAKENHI-PROJECT-23790365, KAKENHI-PROJECT-24247038, KAKENHI-PROJECT-24390261
[Presentation] PGAP6 is involved inshedding og GPI-anchored protein, CRIPTO, which regulates Nodal signaling.2016
- Author(s)
  Lee Gun Hee, Morihisa Fujita, Yoshiko Murakami, Noriyuki Kanzawa, Yusuke Maeda, Taroh Kinoshita.
- Organizer
  第63回日本生化学会近畿支部例会
- Place of Presentation
  神戸薬科大学
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K08303
[Presentation] PGAP4はGPI側鎖の生合成に必須なGPI-GalNAc転移酵素である2015
- Author(s)
  平田哲也, 藤田盛久, 中村昇太, 元岡大祐, 神澤範行, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学安田講堂工学部山上会館
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-15K08303
[Presentation] ゴルジ局在性複数回膜貫通型タンパク質PGAP4はGPI側鎖の合成に必須なGPI-GalNAc転移酵素である2015
- Author(s)
  平田哲也, 藤田盛久, 中村昇太, 元岡大祐, 神澤範行, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08303
[Presentation] 哺乳動物のアルキルアシル型GPIの生合成機構2015
- Author(s)
  神澤範行, 齊藤一伸, 前田裕輔, 藤田盛久, 村上良子, 木下タロウ
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08303
[Presentation] 哺乳動物のアルキルアシル型GPIアンカーの生合成機構2013
- Author(s)
  神澤範行, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25860238
[Presentation] ドリコールリン酸マンノースの利用制限下においてGPIマンノース転移酵素IIによる反応は律速である2013
- Author(s)
  平田哲也, 藤田盛久, 神澤範行, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25860238
[Presentation] 木下タロウ哺乳動物のアルキルアシル型GPIアンカーの生合成機構2013
- Author(s)
  神澤範行, 村上良子, 前田裕輔
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23370060
[Presentation] GPIアンカー型タンパク質の遊離に関わる新規GPI切断酵素2013
- Author(s)
  Lee Gun Hee, 藤田盛久, 村上良子, 神澤範行, 前田裕輔, 木下タロウ
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Data Source
  KAKENHI-PROJECT-25860238
[Presentation] PGAP6 is a novel GPI cleaving enzyme invovled in shedding of GPI-anchored proteins.2013
- Author(s)
  Gun-Hee Lee, Morihisa Fujita, Yoshiko Murakami, Noriyuki Kanzawa, Yusuke Maeda, Taroh Kinoshita
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25860238
[Presentation] ドリコールリン酸マンノース利用制限下におけるGPIアンカー生合成の制御機構2013
- Author(s)
  平田哲也, 藤田盛久, 神澤範行, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Data Source
  KAKENHI-PROJECT-25860238
[Presentation] 哺乳動物のアルキルアシル型GPIアンカーの生合成機構2013
- Author(s)
  神澤範行、村上良子、前田裕輔、木下タロウ
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23370060
[Presentation] Biosynthesis of GPI-anchored proteins requires peroxisome2011
- Author(s)
  Kanzawa N, Maeda Y, Ikeda K, Murakami Y, Fujita M, Shimozawa N, Fujiki Y, Taguchi R and Kinoshita T
- Organizer
  第30回内藤カンファレンス
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790365
[Presentation] Biosynthesis of GPI-anchored proteins requires peroxisome.2011
- Author(s)
  Kanzawa N, Maeda Y, Ikeda K, Murakami Y, Fujita M, Shimozawa N, Fujiki Y, Taguchi R and Kinoshita T
- Organizer
  第30回内藤カンファレンス
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790365
[Presentation] GPI アンカー生合成における脂質リモデリングのアルキル供与体の解明2011
- Author(s)
  神澤範行, 前田裕輔, 藤田盛久, 木下タロウ
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790365
[Presentation] GPIアンカー生合成における脂質リモデリングのアルキル供与体の解明2011
- Author(s)
  神澤範行, 前田裕輔, 藤田盛久, 木下タロウ
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790365
[Presentation] Glycolipid biosynthesis and GPI anchor biosynthesis
- Author(s)
  神澤範行
- Organizer
  国際メタボローム学会第10回国際会議
- Place of Presentation
  東京第一ホテル鶴岡
- Year and Date
  2014-06-23 – 2014-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-25860238
[Presentation] GPIアンカー型タンパク質の細胞膜遊離に関わるGPI切断酵素PGAP6
- Author(s)
  イゴンヒ, 藤田盛久, 村上良子, 神澤範行, 前田裕輔, 木下タロウ
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860238

1. MAEDA YUSUKE (00294124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. FUJIHARA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. MURAKAMI Yoshiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. FUJITA Morihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 木下タロウ

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

KANZAWA Noriyuki 神澤 範行

Research Projects

Research Products

Co-Researchers

GPIアンカーの構造から解明するペルオキシソーム病の病態と発症メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of peroxisomal disorders from the structure of GPI anchorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of pH homeostasis in acidic organelles

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Abnormality of the involvement of glycosylphosphatidylinositol anchor in a peroxisomal disorder.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 生体の科学「細胞の分子構造と機能 -核以外の細胞小器官- GPI アンカーのリモデリングにおけるペルオキシソームの役割とその異常」2012

Author(s)

Data Source

[Journal Article] A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia-mental retardation syndrome2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome and rhizomelic chondrodysplasia punctata2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] PGAP6 is involved inshedding og GPI-anchored protein, CRIPTO, which regulates Nodal signaling.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PGAP4はGPI側鎖の生合成に必須なGPI-GalNAc転移酵素である2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゴルジ局在性複数回膜貫通型タンパク質PGAP4はGPI側鎖の合成に必須なGPI-GalNAc転移酵素である2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 哺乳動物のアルキルアシル型GPIの生合成機構2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 哺乳動物のアルキルアシル型GPIアンカーの生合成機構2013

Author(s)

Organizer

Place of Presentation

KANZAWA Noriyuki 神澤範行