Kurihara Miyako 栗原都

Researcher Number	40453170
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2025: 奈良県立医科大学, 医学部, 研究員 2023: 奈良県立医科大学, 医学部, 研究員 2014 – 2022: 奈良県立医科大学, 医学部附属病院, 研究員 2015: 奈良県立医科大学, 医学部附属病院, 診療助教
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Morphological basic dentistry
Keywords	Principal Investigator 口腔癌 / MIA2 / コレステロール / Warburg効果 / シグナル伝達 / PXDN / MIA family / 癌 / 微小環境 / 転移 / 浸潤・転移 / MIA gene family … More Except Principal Investigator … More 口腔癌 / MIA gene family / 腫瘍マーカー / MIA gene family / TANGO Less

高コレステロール状態における口腔癌細胞の動態とシグナル経路の解明Principal Investigator
- Principal Investigator
  
  栗原都
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nara Medical University
PXDNによるがん代謝と微小環境を標的とした口腔癌の治療ストラテジーPrincipal Investigator
- Principal Investigator
  
  栗原都
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nara Medical University
Elucidation of the function of STOX2, a novel oral cancer-specific gene, and its application to diagnosis and treatment
- Principal Investigator
  
  Sasahira Tomonori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Kagoshima University
  Nara Medical University
New Developments in Molecular Diagnosis and Therapy of Oral Cancer by Targeting MIA2-related SignalsPrincipal Investigator
- Principal Investigator
  
  Kurihara Miyako
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nara Medical University
Elucidation of the pre-metastasis niche formation mechanism of oral cancer by TANGO
- Principal Investigator
  
  Sasahira Tomoonori
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nara Medical University
Search for novel marker for defining microenvironment of metastasis of oral cancerPrincipal Investigator
- Principal Investigator
  
  Kurihara MIyako
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
Novel strategy for molecular diagnosis and treatment in oral cancer by MIA gene family signaling pathway.Principal Investigator
- Principal Investigator
  
  Kurihara Miyako
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University

All 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] SERPINE2 is an oral cancer-promoting factor that induces angiogenesis and lymphangiogenesis2021
- Author(s)
  Sasahira T, Kurihara-Shimomura M, Shimomura H, Kirita T
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 26 Issue: 10 Pages: 1831-1839
- DOI
  10.1007/s10147-021-01970-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-21K10077
[Journal Article] Peroxidan plays a tumor-promoting role in oral squamous cell carcinoma2020
- Author(s)
  Kurihara-Shimomura M, Sasahira T, Shimomura H, Kirita T
- Journal Title
  
  Int J Mol
  
  Volume: 21 Issue: 15 Pages: 5416-5416
- DOI
  10.3390/ijms21155416
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-17K11621
[Journal Article] Sushi repeat containing Protein X-linked 2 Is a downstream signal of LEM domain containing 1 and acts as a2020
- Author(s)
  Sasahira T, Kurihara-Shimomura M, Nishiguchi Y, Shimomura H, Kirita T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 10 Pages: 3655-3655
- DOI
  10.3390/ijms21103655
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-19K10272, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-17K11621
[Journal Article] Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO2020
- Author(s)
  Sasahira T, Kurihara-Shimomura M, Shimomura H, Bosserhoff AK, Kirita T
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 147 Issue: 6 Pages: 1659-1672
- DOI
  10.1007/s00432-021-03568-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-21K10077
[Journal Article] Non-SMC condensin I complex subunit H (NCAPH) is associated with lymphangiogenesis and drug resistance2019
- Author(s)
  Shimomura H, Sasahira T, Nakashima C, Kurihara-Shimomura M, Kirita T
- Journal Title
  
  J Clin Med
  
  Volume: 9 Issue: 1 Pages: 72-72
- DOI
  10.3390/jcm9010072
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-19K10272
[Journal Article] Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma2019
- Author(s)
  Kurihara-Shimomura M, Sasahira T, Shimomura H, Bosserhoff AK, Kirita T
- Journal Title
  
  Int J Oncol
  
  Volume: 56 Pages: 1093-1100
- DOI
  10.3892/ijo.2020.4996
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-19K10272, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-17K11621
[Journal Article] The Oncogenic Activity of miR-29b-1-5p Induces the Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma2018
- Author(s)
  Kurihara-Shimomura M, Sasahira T, Shimomura H, Nakashima C, Kirita T
- Journal Title
  
  J Clin Med
  
  Volume: 8 Issue: 2 Pages: 273-273
- DOI
  10.3390/jcm8020273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09796
[Journal Article] The Multifarious Functions of Pyruvate Kinase M2 in Oral Cancer Cells2018
- Author(s)
  Kurihara-Shimomura M, Sasahira T, Nakashima C, Kuniyasu H, Shimomura H, Kirita T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19 Issue: 10 Pages: 10-10
- DOI
  10.3390/ijms19102907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-17K19923, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16H06276
[Journal Article] NIPA-like domain containing 1 is a novel tumor-promoting factor in oral squamous cell carcinoma2018
- Author(s)
  Sasahira T, Nishiguchi Y, Kurihara-Shimomura M, Nakashima C, Kuniyasu H, Kirita T
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 144 Issue: 5 Pages: 875-882
- DOI
  10.1007/s00432-018-2612-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20602, KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16H06276
[Journal Article] Zinc finger AN1-type containing 4 is a novel marker for predicting metastasis and poor prognosis in oral squamous cell carcinoma2018
- Author(s)
  10.1136/jclinpath-2017-204770
- Journal Title
  
  J Clin Pathol
  
  Volume: 71 Issue: 5 Pages: 436-41
- DOI
  10.1136/jclinpath-2017-204770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16K20602
[Journal Article] Downregulation of DHRS9 is associated with poor prognosis in oral squamous cell carcinoma2018
- Author(s)
  Shimomura H, Sasahira T, Nakashima C, Shimomura-Kurihara M, Kirita T
- Journal Title
  
  Pathology
  
  Volume: 50 Issue: 6 Pages: 642-47
- DOI
  10.1016/j.pathol.2018.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796
[Journal Article] Pancreatic adenocarcinoma upregulated factor has oncogenic functions in oral squamous cell carcinoma.2017
- Author(s)
  Sasahira T, Kurihara M, Nishiguchi Y, Nakashima C, Kirita T, Kuniyasu H.
- Journal Title
  
  Histopathol
  
  Volume: in press Issue: 4 Pages: 539-48
- DOI
  10.1111/his.13097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16K20602, KAKENHI-PROJECT-15H03057, KAKENHI-PROJECT-16H06276
[Journal Article] NEDD 4 binding protein 2-like 1 promotes cancer cell invasion in oral squamous cell carcinoma.2016
- Author(s)
  Sasahira T, Kurihara M, Nishiguchi Y, Fujiwara R, Kirita T; Kuniyasu H
- Journal Title
  
  Virchow Arch
  
  Volume: 469 Issue: 2 Pages: 163-172
- DOI
  10.1007/s00428-016-1955-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602
[Journal Article] Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression.2016
- Author(s)
  Sasahira T, Nishiguchi Y, Fujiwara R, Kurihara M, Kirita T, Katrin BA, Kuniyasu H.
- Journal Title
  
  Oncotarget
  
  Volume: vol.7 Issue: 18 Pages: 26751-64
- DOI
  10.18632/oncotarget.8495
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11262, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602, KAKENHI-PROJECT-16H06276
[Journal Article] LEM domain containing 1 promotes oral squamous cell carcinoma invasion and endothelial transmigration.2016
- Author(s)
  Sasahira T, Kurihara M, Nakashima C, Kirita T, Kuniyasu H
- Journal Title
  
  Br J Cancer
  
  Volume: 115 Issue: 1 Pages: 52-58
- DOI
  10.1038/bjc.2016.167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602
[Journal Article] A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma.2016
- Author(s)
  Sasahira T, Kirita T, Nishiguchi Y, Kurihara M, Nakashima C, Bosserhoff AK, Kuniyasu H.
- Journal Title
  
  Oncotarget
  
  Volume: May 16 Issue: 21 Pages: 1-16
- DOI
  10.18632/oncotarget.9082
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11262, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602
[Presentation] NCAPHは口腔癌のリンパ管新生、抗癌剤耐性に関与する2021
- Author(s)
  下村弘幸、栗原　都、桐田忠昭、笹平智則
- Organizer
  第39日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-18K09796
[Presentation] Mast cell chymaseはMIA gene familを介した脈管新生を促進する2021
- Author(s)
  栗原　都、笹平智則、桐田忠昭
- Organizer
  第39日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-20K09912
[Presentation] SRPX2は口腔癌における新規腫瘍促進因子である2021
- Author(s)
  笹平智則、栗原　都、下村弘幸、桐田忠昭
- Organizer
  第39日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-18K09796
[Presentation] SRPX2は口腔癌における新規腫瘍促進因子である2021
- Author(s)
  笹平智則、栗原　都、下村弘幸、桐田忠昭
- Organizer
  第39日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-20K09912
[Presentation] Mast cell chymaseはMIA gene familを介した脈管新生を促進する2021
- Author(s)
  栗原　都、笹平智則、桐田忠昭
- Organizer
  第39日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-18K09796
[Presentation] NCAPHは口腔癌のリンパ管新生、抗癌剤耐性に関与する2021
- Author(s)
  下村弘幸、栗原　都、桐田忠昭、笹平智則
- Organizer
  第39日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-20K09912
[Presentation] SRPX2はLEMD1の下流シグナルであり、口腔癌において腫瘍促進性に作用する新規分子である2020
- Author(s)
  笹平智則、栗原　都、下村弘幸、桐田忠昭
- Organizer
  第31回日本臨床口腔病理学会総会
- Data Source
  KAKENHI-PROJECT-18K09796
[Presentation] SRPX2はLEMD1の下流シグナルであり、口腔癌において腫瘍促進性に作用する新規分子である2020
- Author(s)
  笹平智則、栗原　都、下村弘幸、桐田忠昭
- Organizer
  第31回日本臨床口腔病理学会総会
- Data Source
  KAKENHI-PROJECT-20K09912
[Presentation] Malic enzyme 1 による口腔扁平上皮癌促進作用2018
- Author(s)
  中嶋千恵、栗原　都、山本一彦、バワールウジャール、笹平智則、桐田忠昭、國安弘基
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K20602
[Presentation] 口腔扁平上皮癌におけるピルビン酸キナーゼ・アイソザイムの発現2016
- Author(s)
  栗原　都、笹平智則、山本一彦、國安弘基、桐田忠昭
- Organizer
  第34回日本口腔腫瘍学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-26861742
[Presentation] 口腔扁平上皮癌におけるN4BP2L1の役割2015
- Author(s)
  笹平智則、栗原　都、バワール・ウジャール、桐田忠昭、國安弘基
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26861742
[Presentation] 口腔および食道扁平上皮癌におけるピルビン酸キナーゼ・アイソゾームの発現2015
- Author(s)
  栗原　都、桐田忠昭、中嶋智恵、笹平智則、バワール・ウジャール、佐々木隆光、國安弘基
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861742
[Presentation] 口腔扁平上皮癌におけるMIA2の役割
- Author(s)
  栗原　都
- Organizer
  日本病理学会総会
- Place of Presentation
  広島　広島国際会議場
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26861742
[Presentation] Expression of isozymes of pyruvate kinase in esophageal cancer
- Author(s)
  栗原　都
- Organizer
  日本癌学会
- Place of Presentation
  横浜　パシフィコ横浜
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26861742
[Presentation] 口腔癌におけるピルビン酸キナーゼ作用の多様性
- Author(s)
  栗原　都
- Organizer
  日本頭頸部癌学会
- Place of Presentation
  東京　東京ファッションタウン
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26861742
[Presentation] 口腔扁平上皮癌におけるピルビン酸キナーゼ・アイソザイム変換の意義
- Author(s)
  栗原　都
- Organizer
  日本病理学会総会
- Place of Presentation
  広島　広島国際会議場
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26861742

1. Sasahira Tomoonori (90405374)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
2. 桐田忠昭 (70201465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 金氏毅 (30611660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 加治屋由佳 (30979589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 国安弘基

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Kurihara Miyako 栗原 都

Research Projects

Research Products

Co-Researchers

高コレステロール状態における口腔癌細胞の動態とシグナル経路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PXDNによるがん代謝と微小環境を標的とした口腔癌の治療ストラテジーPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of STOX2, a novel oral cancer-specific gene, and its application to diagnosis and treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New Developments in Molecular Diagnosis and Therapy of Oral Cancer by Targeting MIA2-related SignalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pre-metastasis niche formation mechanism of oral cancer by TANGO

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for novel marker for defining microenvironment of metastasis of oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel strategy for molecular diagnosis and treatment in oral cancer by MIA gene family signaling pathway.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] SERPINE2 is an oral cancer-promoting factor that induces angiogenesis and lymphangiogenesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peroxidan plays a tumor-promoting role in oral squamous cell carcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sushi repeat containing Protein X-linked 2 Is a downstream signal of LEM domain containing 1 and acts as a2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-SMC condensin I complex subunit H (NCAPH) is associated with lymphangiogenesis and drug resistance2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Oncogenic Activity of miR-29b-1-5p Induces the Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma2018

Author(s)

Journal Title

DOI

Kurihara Miyako 栗原都