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Kurihara Miyako  栗原 都

ORCIDConnect your ORCID iD *help
Researcher Number 40453170
Affiliation (Current) 2025: 奈良県立医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help 2025: 奈良県立医科大学, 医学部, 研究員
2023: 奈良県立医科大学, 医学部, 研究員
2014 – 2022: 奈良県立医科大学, 医学部附属病院, 研究員
2015: 奈良県立医科大学, 医学部附属病院, 診療助教
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Except Principal Investigator
Basic Section 57020:Oral pathobiological science-related / Morphological basic dentistry
Keywords
Principal Investigator
口腔癌 / Warburg効果 / シグナル伝達 / PXDN / MIA2 / MIA family / 癌 / 微小環境 / 転移 / 浸潤・転移 / MIA gene family … More
Except Principal Investigator
… More 口腔癌 / MIA gene family / 腫瘍マーカー / MIA gene family / TANGO Less
  • Research Projects

    (7 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (3 People)
  •  高コレステロール状態における口腔癌細胞の動態とシグナル経路の解明Principal Investigator

    • Principal Investigator
      栗原 都
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Nara Medical University
  •  PXDNによるがん代謝と微小環境を標的とした口腔癌の治療ストラテジーPrincipal Investigator

    • Principal Investigator
      栗原 都
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Nara Medical University
  •  Elucidation of the function of STOX2, a novel oral cancer-specific gene, and its application to diagnosis and treatment

    • Principal Investigator
      Sasahira Tomonori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Kagoshima University
      Nara Medical University
  •  New Developments in Molecular Diagnosis and Therapy of Oral Cancer by Targeting MIA2-related SignalsPrincipal Investigator

    • Principal Investigator
      Kurihara Miyako
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Nara Medical University
  •  Elucidation of the pre-metastasis niche formation mechanism of oral cancer by TANGO

    • Principal Investigator
      Sasahira Tomoonori
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Nara Medical University
  •  Search for novel marker for defining microenvironment of metastasis of oral cancerPrincipal Investigator

    • Principal Investigator
      Kurihara MIyako
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nara Medical University
  •  Novel strategy for molecular diagnosis and treatment in oral cancer by MIA gene family signaling pathway.Principal Investigator

    • Principal Investigator
      Kurihara Miyako
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nara Medical University

All 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

  • [Journal Article] SERPINE2 is an oral cancer-promoting factor that induces angiogenesis and lymphangiogenesis2021

    • Author(s)
      Sasahira T, Kurihara-Shimomura M, Shimomura H, Kirita T
    • Journal Title

      Int J Clin Oncol

      Volume: 26 Issue: 10 Pages: 1831-1839

    • DOI

      10.1007/s10147-021-01970-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-21K10077
  • [Journal Article] Peroxidan plays a tumor-promoting role in oral squamous cell carcinoma2020

    • Author(s)
      Kurihara-Shimomura M, Sasahira T, Shimomura H, Kirita T
    • Journal Title

      Int J Mol

      Volume: 21 Issue: 15 Pages: 5416-5416

    • DOI

      10.3390/ijms21155416

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-17K11621
  • [Journal Article] Sushi repeat containing Protein X-linked 2 Is a downstream signal of LEM domain containing 1 and acts as a2020

    • Author(s)
      Sasahira T, Kurihara-Shimomura M, Nishiguchi Y, Shimomura H, Kirita T
    • Journal Title

      Int J Mol Sci

      Volume: 21 Issue: 10 Pages: 3655-3655

    • DOI

      10.3390/ijms21103655

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-19K10272, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-17K11621
  • [Journal Article] Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO2020

    • Author(s)
      Sasahira T, Kurihara-Shimomura M, Shimomura H, Bosserhoff AK, Kirita T
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 147 Issue: 6 Pages: 1659-1672

    • DOI

      10.1007/s00432-021-03568-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-21K10077
  • [Journal Article] Non-SMC condensin I complex subunit H (NCAPH) is associated with lymphangiogenesis and drug resistance2019

    • Author(s)
      Shimomura H, Sasahira T, Nakashima C, Kurihara-Shimomura M, Kirita T
    • Journal Title

      J Clin Med

      Volume: 9 Issue: 1 Pages: 72-72

    • DOI

      10.3390/jcm9010072

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-19K10272
  • [Journal Article] Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma2019

    • Author(s)
      Kurihara-Shimomura M, Sasahira T, Shimomura H, Bosserhoff AK, Kirita T
    • Journal Title

      Int J Oncol

      Volume: 56 Pages: 1093-1100

    • DOI

      10.3892/ijo.2020.4996

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-19K10272, KAKENHI-PROJECT-20K09912, KAKENHI-PROJECT-17K11621
  • [Journal Article] The Oncogenic Activity of miR-29b-1-5p Induces the Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma2018

    • Author(s)
      Kurihara-Shimomura M, Sasahira T, Shimomura H, Nakashima C, Kirita T
    • Journal Title

      J Clin Med

      Volume: 8 Issue: 2 Pages: 273-273

    • DOI

      10.3390/jcm8020273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09796
  • [Journal Article] The Multifarious Functions of Pyruvate Kinase M2 in Oral Cancer Cells2018

    • Author(s)
      Kurihara-Shimomura M, Sasahira T, Nakashima C, Kuniyasu H, Shimomura H, Kirita T
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 10 Pages: 10-10

    • DOI

      10.3390/ijms19102907

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-17K19923, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16H06276
  • [Journal Article] NIPA-like domain containing 1 is a novel tumor-promoting factor in oral squamous cell carcinoma2018

    • Author(s)
      Sasahira T, Nishiguchi Y, Kurihara-Shimomura M, Nakashima C, Kuniyasu H, Kirita T
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 144 Issue: 5 Pages: 875-882

    • DOI

      10.1007/s00432-018-2612-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K20602, KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16H06276
  • [Journal Article] Zinc finger AN1-type containing 4 is a novel marker for predicting metastasis and poor prognosis in oral squamous cell carcinoma2018

    • Author(s)
      10.1136/jclinpath-2017-204770
    • Journal Title

      J Clin Pathol

      Volume: 71 Issue: 5 Pages: 436-41

    • DOI

      10.1136/jclinpath-2017-204770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16K20602
  • [Journal Article] Downregulation of DHRS9 is associated with poor prognosis in oral squamous cell carcinoma2018

    • Author(s)
      Shimomura H, Sasahira T, Nakashima C, Shimomura-Kurihara M, Kirita T
    • Journal Title

      Pathology

      Volume: 50 Issue: 6 Pages: 642-47

    • DOI

      10.1016/j.pathol.2018.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11621, KAKENHI-PROJECT-18K09796
  • [Journal Article] Pancreatic adenocarcinoma upregulated factor has oncogenic functions in oral squamous cell carcinoma.2017

    • Author(s)
      Sasahira T, Kurihara M, Nishiguchi Y, Nakashima C, Kirita T, Kuniyasu H.
    • Journal Title

      Histopathol

      Volume: in press Issue: 4 Pages: 539-48

    • DOI

      10.1111/his.13097

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16K20602, KAKENHI-PROJECT-15H03057, KAKENHI-PROJECT-16H06276
  • [Journal Article] NEDD 4 binding protein 2-like 1 promotes cancer cell invasion in oral squamous cell carcinoma.2016

    • Author(s)
      Sasahira T, Kurihara M, Nishiguchi Y, Fujiwara R, Kirita T; Kuniyasu H
    • Journal Title

      Virchow Arch

      Volume: 469 Issue: 2 Pages: 163-172

    • DOI

      10.1007/s00428-016-1955-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602
  • [Journal Article] Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression.2016

    • Author(s)
      Sasahira T, Nishiguchi Y, Fujiwara R, Kurihara M, Kirita T, Katrin BA, Kuniyasu H.
    • Journal Title

      Oncotarget

      Volume: vol.7 Issue: 18 Pages: 26751-64

    • DOI

      10.18632/oncotarget.8495

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11262, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602, KAKENHI-PROJECT-16H06276
  • [Journal Article] LEM domain containing 1 promotes oral squamous cell carcinoma invasion and endothelial transmigration.2016

    • Author(s)
      Sasahira T, Kurihara M, Nakashima C, Kirita T, Kuniyasu H
    • Journal Title

      Br J Cancer

      Volume: 115 Issue: 1 Pages: 52-58

    • DOI

      10.1038/bjc.2016.167

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602
  • [Journal Article] A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma.2016

    • Author(s)
      Sasahira T, Kirita T, Nishiguchi Y, Kurihara M, Nakashima C, Bosserhoff AK, Kuniyasu H.
    • Journal Title

      Oncotarget

      Volume: May 16 Issue: 21 Pages: 1-16

    • DOI

      10.18632/oncotarget.9082

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11262, KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-26462790, KAKENHI-PROJECT-16K20602
  • [Presentation] NCAPHは口腔癌のリンパ管新生、抗癌剤耐性に関与する2021

    • Author(s)
      下村弘幸、栗原 都、桐田忠昭、笹平智則
    • Organizer
      第39日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-18K09796
  • [Presentation] Mast cell chymaseはMIA gene familを介した脈管新生を促進する2021

    • Author(s)
      栗原 都、笹平智則、桐田忠昭
    • Organizer
      第39日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-20K09912
  • [Presentation] SRPX2は口腔癌における新規腫瘍促進因子である2021

    • Author(s)
      笹平智則、栗原 都、下村弘幸、桐田忠昭
    • Organizer
      第39日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-18K09796
  • [Presentation] SRPX2は口腔癌における新規腫瘍促進因子である2021

    • Author(s)
      笹平智則、栗原 都、下村弘幸、桐田忠昭
    • Organizer
      第39日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-20K09912
  • [Presentation] Mast cell chymaseはMIA gene familを介した脈管新生を促進する2021

    • Author(s)
      栗原 都、笹平智則、桐田忠昭
    • Organizer
      第39日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-18K09796
  • [Presentation] NCAPHは口腔癌のリンパ管新生、抗癌剤耐性に関与する2021

    • Author(s)
      下村弘幸、栗原 都、桐田忠昭、笹平智則
    • Organizer
      第39日本口腔腫瘍学会総会
    • Data Source
      KAKENHI-PROJECT-20K09912
  • [Presentation] SRPX2はLEMD1の下流シグナルであり、口腔癌において腫瘍促進性に作用する新規分子である2020

    • Author(s)
      笹平智則、栗原 都、下村弘幸、桐田忠昭
    • Organizer
      第31回日本臨床口腔病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K09796
  • [Presentation] SRPX2はLEMD1の下流シグナルであり、口腔癌において腫瘍促進性に作用する新規分子である2020

    • Author(s)
      笹平智則、栗原 都、下村弘幸、桐田忠昭
    • Organizer
      第31回日本臨床口腔病理学会総会
    • Data Source
      KAKENHI-PROJECT-20K09912
  • [Presentation] Malic enzyme 1 による口腔扁平上皮癌促進作用2018

    • Author(s)
      中嶋千恵、栗原 都、山本一彦、バワール ウジャール、笹平智則、桐田忠昭、國安弘基
    • Organizer
      第76回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-16K20602
  • [Presentation] 口腔扁平上皮癌におけるピルビン酸キナーゼ・アイソザイムの発現2016

    • Author(s)
      栗原 都、笹平智則、山本一彦、國安弘基、桐田忠昭
    • Organizer
      第34回日本口腔腫瘍学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-01-21
    • Data Source
      KAKENHI-PROJECT-26861742
  • [Presentation] 口腔扁平上皮癌におけるN4BP2L1の役割2015

    • Author(s)
      笹平智則、栗原 都、バワール・ウジャール、桐田忠昭、國安弘基
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-26861742
  • [Presentation] 口腔および食道扁平上皮癌におけるピルビン酸キナーゼ・アイソゾームの発現2015

    • Author(s)
      栗原 都、桐田忠昭、中嶋智恵、笹平智則、バワール・ウジャール、佐々木隆光、國安弘基
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26861742
  • [Presentation] 口腔扁平上皮癌におけるMIA2の役割

    • Author(s)
      栗原 都
    • Organizer
      日本病理学会総会
    • Place of Presentation
      広島 広島国際会議場
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-26861742
  • [Presentation] Expression of isozymes of pyruvate kinase in esophageal cancer

    • Author(s)
      栗原 都
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜 パシフィコ横浜
    • Year and Date
      2014-09-24 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-26861742
  • [Presentation] 口腔癌におけるピルビン酸キナーゼ作用の多様性

    • Author(s)
      栗原 都
    • Organizer
      日本頭頸部癌学会
    • Place of Presentation
      東京 東京ファッションタウン
    • Year and Date
      2014-06-12 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26861742
  • [Presentation] 口腔扁平上皮癌におけるピルビン酸キナーゼ・アイソザイム変換の意義

    • Author(s)
      栗原 都
    • Organizer
      日本病理学会総会
    • Place of Presentation
      広島 広島国際会議場
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-26861742
  • 1.  Sasahira Tomoonori (90405374)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 19 results
  • 2.  桐田 忠昭 (70201465)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  国安 弘基
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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