ITOH Yuka 伊藤友香

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Itoh Yuka 伊藤友香

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Researcher Number	40454326
Other IDs
External Links
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 山梨大学, 大学院総合研究部, 助教 2018 – 2022: 山梨大学, 大学院総合研究部, 特任助教 2019: 山梨大学, 総合研究部, 助教 2014 – 2015: 名古屋市立大学, 薬学研究科(研究院), 助教 2010 – 2011: 名古屋市立大学, 大学院・薬学研究科, 助教 2009: 名古屋市立大学, 大学院・薬学研究科・薬学研究科, 助教 2007 – 2008: Aichi Gakuin University, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy Except Principal Investigator Biological pharmacy / General pharmacology
Keywords	Principal Investigator TGF-β / Smad / シグナル伝達 / 転写 / がん / 発現制御 / Smad2 / 転写制御 / がん悪性化 / グリオーマ … More / Smad cofactor / AP-1 / Smad複合体 / 転写活性化 / TRBファミリータンパク質 / TGFβ / TRB1 / 細胞・組織 / スフィンゴシルホスホリルコリン / アポトーシス / カルシウムイオン / ストレス / 細胞死 … More Except Principal Investigator RORα / EBPβ / C / 膵β細胞 / Cdc25A / 肝細胞 / Smad3 / 脂肪滴 / 脂肪組胞 / perilipin / IL-2 / PPARγ / 小胞体ストレス / TRB1 / メタボリックシンドローム / β細胞 / 脂肪細胞 / TGFβ / TRB3 / ストレス / アセチル化 / メチル化 / イオンチャネル / 転写制御 / ヒストン / ステロイド / TRP / 転写 / エピジェネティクス / カチオンチャネル Less

がん悪性化形質獲得に伴うSmad4機能活性化機構の解明Principal Investigator
- Principal Investigator
  
  伊藤友香
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Yamanashi
Smad2とSmad cofactorの相互作用によるがん悪性化抑制機構の解明Principal Investigator
- Principal Investigator
  
  伊藤友香
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Yamanashi
Visualization of the Smad-Smad cofactor cooperativity in cancer progressionPrincipal Investigator
- Principal Investigator
  
  伊藤友香
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Yamanashi
Molecular mechanism for transcriptional activation by the Smad complexPrincipal Investigator
- Principal Investigator
  
  ITOH Yuka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Yamanashi
Regulation of oncogenic activities by TRB1 through TGF-beta signalingPrincipal Investigator
- Principal Investigator
  
  Itoh Yuka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Downregulation of lipid droplets formation in adipocyte by TGFβand identification of its regulatorPrincipal Investigator
- Principal Investigator
  
  ITOH Yuka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Crosstalk between stress and cytokine signaling in metabolic syndrome
- Principal Investigator
  
  HAYASHI Hidetoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Regulation of expression of vascular cation channels by transcriptional and epigenetical modulation
- Principal Investigator
  
  MURAKI Katsuhiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Aichi Gakuin University
Regulation of cell death by HRD1Principal Investigator
- Principal Investigator
  
  伊藤友香
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Aichi Gakuin University

All 2024 2023 2019 2018 2016 2015 2014 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Receptor-activated transcription factors and beyond: multiple modes of Smad2/3-dependent transmission of TGF-β signaling2024
- Author(s)
  Miyazawa Keiji、Itoh Yuka、Fu Hao、Miyazono Kohei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 5 Pages: 107256-107256
- DOI
  10.1016/j.jbc.2024.107256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0400, KAKENHI-PROJECT-20H00513, KAKENHI-PROJECT-23K21385
[Journal Article] A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation.2019
- Author(s)
  Itoh Y, Koinuma D, Omata C, Ogami T, Motizuki M, Yaguchi SI, Itoh T, Miyake K, Tsutsumi S, Aburatani H, Saitoh M, Miyazono K, Miyazawa K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Issue: 42 Pages: 15466-15479
- DOI
  10.1074/jbc.ra119.009877
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06626, KAKENHI-PROJECT-18H02969, KAKENHI-PROJECT-17K19589
[Journal Article] Regulation of Epithelial-Mesenchymal Transition by E3 Ubiquitin Ligases and Deubiquitinase in Cancer2016
- Author(s)
  Inoue Y, Itoh Y, Sato K, Kawasaki F, Sumita C, Tanaka T, Morishita D, Hayashi H.
- Journal Title
  
  Curr Cancer Drug Targets
  
  Volume: 16 Pages: 110-118
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860042
[Journal Article] Tribbles-Related Protein Family Members as Regulators or Substrates of the Ubiquitin-Proteasome System in Cancer Development2016
- Author(s)
  Sakai S, Miyajima C, Uchida C, Itoh Y, Hayashi H, Inoue Y.
- Journal Title
  
  Curr Cancer Drug Targets
  
  Volume: 16 Pages: 147-156
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860042
[Journal Article] Positive Regulation of Interleukin-2 Expression by a Pseudokinase, Tribbles 1, in Activated T Cells2015
- Author(s)
  Miyajima C, Itoh Y, Inoue Y, Hayashi H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 8 Pages: 1126-1133
- DOI
  10.1248/bpb.b15-00002
- NAID
  130005090659
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07936, KAKENHI-PROJECT-15K07937, KAKENHI-PROJECT-26860042
[Journal Article] The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.2014
- Author(s)
  Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Yuka Itoh, Satoko Kimura, Hidetoshi Hayashi, Kikuo Onozaki, Yoshiaki Ohi, Akira Haji, Katsuhiko Muraki
- Journal Title
  
  American Journal of Physiology -Cell Physiology
  
  Volume: 307 Issue: 4 Pages: C384-C394
- DOI
  10.1152/ajpcell.00182.2013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590085, KAKENHI-PROJECT-26460349, KAKENHI-PROJECT-26860042, KAKENHI-PROJECT-26870677
[Journal Article] Dihydrotestosterone inhibits IL-1α or TNF-α-induced proinflammatory cytokine production via androgen receptor-dependent inhibition of NF-κB activation in rheumatoid fibroblast-like synovial cell line2011
- Author(s)
  J. Xu, Y. Itoh, H. Hayashi, T. Takii, K. Miyazawa, K. Onozaki
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Pages: 1724-1730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Dihydrotestosterone Inhibits Interleukin-1.ALPHA. or Tumor Necrosis Factor .ALPHA.-Induced Proinflammatory Cytokine Production via Androgen Receptor-Dependent Inhibition of Nuclear Factor-.KAPPA.B Activation in Rheumatoid Fibroblast-Like Synovial Cell Line2011
- Author(s)
  Jian Xu, Yuka Itoh, Hidetoshi Hayashi, Takemasa Takii, Keiji Miyazawa, Kikuo Onozaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 11 Pages: 1724-1730
- DOI
  10.1248/bpb.34.1724
- NAID
  130001252856
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067, KAKENHI-PROJECT-22790078
[Journal Article] Dihydrotestosterone inhibits interleukin-1α or tumor necrosis factorα-induced proinflammatory cytokine production via androgen receptor-dependent inhibition of nuclear factor-κB activation in rheumatoid fibroblast-like synovial cell line2011
- Author(s)
  Xu J, Itoh Y, Hayashi H, Takii T, Miyazawa K, Onozaki K
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Pages: 1724-1730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790078
[Journal Article] Ca透過性カチオンチャネル遺伝子発現のエピジェネティクス制御と降圧薬感受性への影響2010
- Author(s)
  伊藤友香、波多野紀行、村木克彦
- Journal Title
  
  臨床薬理の進歩 31
  
  Pages: 40-51
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] Ca透過性カチオンチャネル遺伝子発現のエピジェネティクス制御と降圧薬感受性への影響2010
- Author(s)
  伊藤友香、波多野紀行、村木克彦
- Journal Title
  
  臨床薬理の進歩
  
  Volume: 31 Pages: 40-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790078
[Journal Article] IL-1-induced ERK1/2 activation up-regulates p21Wafl/Cipl protein by inhibition of degradation via ubiquitin independent pathway in human melanoma cells A3752010
- Author(s)
  T.Arakawa, H.Hayashi, S.Itoh, T.Takii, K.Onozaki
- Journal Title
  
  Biochemical and Biophysical Research Communications 392(3)
  
  Pages: 369-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Ca透過性カチオンチャネル遺伝子発現のエピジェネティクス制御と降圧薬感受性への影響2010
- Author(s)
  伊藤友香
- Journal Title
  
  臨床薬理の進歩
  
  Volume: 31 Pages: 40-51
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] IL-1-induced ERK1/2 activation up-regulates p21 Waf1/Cip1 protein by inhibition of degradation via ubiquitin independent pathway in human melanoma cells A375.2010
- Author(s)
  T.Arakawa, H.Hayashi, S.Itoh, T.Takii, K.Onozaki
- Journal Title
  
  Biochemical & Biophysical Research Communication
  
  Volume: 392(3) Pages: 369-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] Cardiac fibroblasts have functional TRPV4 activated by 4α-phorbol 12,13-didecanoate.2009
- Author(s)
  波多野紀行, 伊藤友香, 村木克彦
- Journal Title
  
  Life Sci. 85
  
  Pages: 808-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] An environmental sensor, TRPV4 is a novel regulator of intracellular Ca^<2+> in human synoviocytes.2009
- Author(s)
  Y Itoh, N Hatano, H Hayashi, K Onozaki, K Miyazawa, K Muraki
- Journal Title
  
  Am.J.Physiol., Cell-Physiol. 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] An environmental sensor, TRPV4 is a novel regulator of intracellular Ca^<2+> of human synoviocytes2009
- Author(s)
  Y.Itoh, N.Hatano, H.Hayashi, K.Onozaki, K.Miyazawa, K.Muraki
- Journal Title
  
  American Journal of Physiology-Cell Physiology 297(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590067
[Journal Article] An environmental sensor, TRPV4 is a novel regulator of intracellular Ca2+ in human synoviocytes2009
- Author(s)
  Itoh., et al.
- Journal Title
  
  American Journal of Physiology 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] Cell-culture dependent change of Ca response of rat aortic myocytes to sphingosine-1-phosphate.2008
- Author(s)
  R Tanaka, K Muraki, S Ohya, Y Itoh, N Hatano, Y Imaizumi
- Journal Title
  
  J Pharmcol Sci. 107
  
  Pages: 434-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] Cell-culture-dependent change of Ca2+ response of rat aortic myocytes to sphingosine-1-phosphate2008
- Author(s)
  Tanaka R, Muraki K, Ohya S, Itoh Y, Hatano N, and Imaizumi Y.
- Journal Title
  
  Journal of Pharmacological Sciences 107
  
  Pages: 434-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] TRPV4-Like Non-selective Cation Currents in Cultured Aortic Myocytes2008
- Author(s)
  Tanaka R, Muraki K, Ohya S, Yamamura H, Hatano N, Itoh Y, and Imaizumi Y
- Journal Title
  
  Journal of Pharmacological Scencies 108
  
  Pages: 179-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] Regulation of vascular tone by purinoceptor-activation in vascular smooth muscle and endothelial cells2008
- Author(s)
  Itoh Y, et al
- Journal Title
  
  AICHI-GAKUIN J. PHARMACEUT. SCI. 1
  
  Pages: 31-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] H_2O_2はcGMP非依存的にPKGを活性化して平滑筋弛緩反応を惹起する2008
- Author(s)
  伊藤友香
- Journal Title
  
  ファルマシア 44
  
  Pages: 568-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] H_2O_2はcGMP非依存的にPKGを活性化して平滑筋弛緩反応を惹起する2008
- Author(s)
  伊藤友香
- Journal Title
  
  ファルマシア 44(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] TRPV4-like non-selective cation currents in cultured aortic myocytes.2008
- Author(s)
  R Tanaka, K Muraki, S Ohya, H Yamamura, N Hatano, Y Itoh, Y Imaizumi
- Journal Title
  
  J Pharmcol Sci. 108
  
  Pages: 179-189
- NAID
  10024384928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] Cigarette smoke condensate upregulates the gene and protein expression of proinflammatory cytokines in human fibroblast-like synoviocyte line2008
- Author(s)
  Shizu M, Itoh Y, Sunahara R, Chujo S, Hayashi H, Ide Y, Takii T, Koshiko M, Chung SW, Hayakawa K, Miyazawa K, Hirose K, and Onozaki K.
- Journal Title
  
  Journal of Interferon and Cytokine Reserch 28
  
  Pages: 509-521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] Regulation of vascular tone by purinoceptor-activation in vascular smooth muscle and endothelial cells2008
- Author(s)
  Itoh Y, Hatano N, and Muraki K.
- Journal Title
  
  The Aichi Gakuin Journal of Pharmaceutical Sciences 1
  
  Pages: 31-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890238
[Journal Article] Regulation of vascular tone by purinoceptor-activation in vascular smooth muscle and endothelial cells.2008
- Author(s)
  Itoh, et al
- Journal Title
  
  Aichi-Gakuin J. Pharmceut. Sci. 1
  
  Pages: 31-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Journal Article] Regulation of vascular tone by purinoceptor-activation in vascular smooth muscle and endothelial cells.2008
- Author(s)
  伊藤友香, 波多野紀行, 村木克彦
- Journal Title
  
  Aichi-Gakuin J.Pharmceut.Sci. 1
  
  Pages: 31-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] Cooperation of Smad3 with Ets2 in regulation of TGF-β target gene expression2023
- Author(s)
  Yuka Itoh
- Organizer
  TGFβ meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0400
[Presentation] Transcription activation by TGF-β through the Smad-binding element and CAGA motifs2019
- Author(s)
  Yuka Itoh, Daizo Koinuma, Masao Saitoh, Keiji Miyazawa
- Organizer
  The TGF-β Superfamily Conference: Signaling in Development and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06626
[Presentation] TGF-βシグナル伝達分子SmadとETSファミリー転写因子による協調的な転写制御2019
- Author(s)
  伊藤友香、小俣千帆、三宅邦夫、齋藤正夫、宮澤恵二
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06626
[Presentation] TGF-βによる転写制御とSmad結合配列の多様性2018
- Author(s)
  伊藤友香、宮澤恵二
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06626
[Presentation] pseudokinase TRB1によるインスリンを介した糖代謝関連因子の新たな制御機構2016
- Author(s)
  都築香里、伊藤友香、井上靖道、林　秀敏
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] 脱ユビキチン化酵素による EMT 関連転写因子 Snail タンパクの発現制御2015
- Author(s)
  佐藤晃一、井上靖道、伊藤友香、林秀敏
- Organizer
  フォーラム2015：衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] HepG2細胞におけるCYP3A4タンパク質の発現制御2015
- Author(s)
  宮田和弥、森本真宗、伊藤友香、井上靖道、林　秀敏
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] Loxl2によるTGF-β誘導性上皮間葉転換の制御機構の解析2015
- Author(s)
  田中孝仁、西尾愛梨紗、井上靖道、隅田ちひろ、伊藤友香、林秀敏
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] 転写共役因子 TAZ による p53活性制御機構の解析2015
- Author(s)
  三田村佳奈、井上靖道、鈴木千晶、伊藤友香、林秀敏
- Organizer
  フォーラム2015：衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] PAI-1遺伝子発現制御における Smad と p53とのクロストーク2015
- Author(s)
  川崎文寛、川原田祐貴、井上靖道、伊藤友香、林秀敏
- Organizer
  フォーラム2015：衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] 小胞体ストレス誘導剤およびサイトカインによるCYP1A1の発現制御2015
- Author(s)
  今井和弘、山田莉香子、伊藤友香、井上靖道、林　秀敏
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] 細胞がん化におけるTRB1の生理機能とがん分子標的としての可能性2015
- Author(s)
  鈴木千晶、宮嶋ちはる、井上靖道、岩中広美、伊藤友香、林　秀敏
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] T細胞におけるTRB3を介したインターロイキン2発現の制御機構2015
- Author(s)
  野原　匠、杉山和弥、宮嶋ちはる、伊藤友香、井上靖道、林　秀敏
- Organizer
  第16回Pharmaco-Haematology Symposium
- Place of Presentation
  東京
- Year and Date
  2015-06-13
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] TGF-βによるTRB1の発現制御とTGF-βシグナルにおけるTRB1の機能2015
- Author(s)
  澤中美希、水川絵理子、伊藤友香、井上靖道、林秀敏
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] ストレスセンサータンパク質TRB3を介した小胞体ストレスによるインターロイキン2の発現制御2014
- Author(s)
  野原　匠、杉山和弥、宮嶋ちはる、伊藤友香、井上靖道、林　秀敏
- Organizer
  第60回日本薬学会東海支部総会・大会　2014
- Place of Presentation
  鈴鹿医療科学大学白子キャンパス
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] TGFβによるPPARγ発現抑制と脂肪蓄積の制御2014
- Author(s)
  楽　怡、鈴木美沙紀、井上万由美、伊藤友香、岡山敦子、野口祐美子、舛田悠介、井上靖道、小野嵜菊夫、斉藤昌之、林　秀敏
- Organizer
  第15回Pharmaco-Hematology Symposium
- Place of Presentation
  名古屋
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] シュードキナーゼTRB1のTGF-βによる発現制御と機能解析2014
- Author(s)
  澤中美希、伊藤友香、井上靖道、林秀敏
- Organizer
  第60回日本薬学会東海支部総会・大会　2014
- Place of Presentation
  鈴鹿医療科学大学白子キャンパス
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] 小胞体ストレス誘導性タンパク質TRB3によるインターロイキン2の発現制御2014
- Author(s)
  野原　匠、杉山和弥、宮嶋ちはる、伊藤友香、井上靖道、林　秀敏
- Organizer
  フォーラム2014　衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-26860042
[Presentation] TGF-βによるペリリピン1遺伝子発現抑制と脂肪滴形成の制御2012
- Author(s)
  楽怡、伊藤友香、井上靖道、小野嵜菊夫、斉藤昌之、林秀敏
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790078
[Presentation] TGF-βによるペリリピン1遺伝子発現抑制と脂肪滴形成の制御2012
- Author(s)
  楽恰、伊藤友香、井上靖道、小野嵜菊夫、斉藤昌之、林秀敏
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレス誘導性分子TRB3によるインターロイキン2の転写制御機構の解析2012
- Author(s)
  杉山和弥, 西仲駿, 伊藤友香, 井上靖道, 酒井聡, 小野嵜菊夫, 林秀敏
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGF-βによるペリリピン1遺伝子発現抑制を脂肪滴形成の制御2012
- Author(s)
  楽怡、伊藤友香、井上靖道、小野寄菊夫、斉藤昌之、林秀敏
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790078
[Presentation] ストレスセンサータンパク質TRB3によるIL-2転写制御機構の解析2011
- Author(s)
  杉山和弥, 西仲駿, 伊藤友香, 井上靖道, 酒井聡, 小野嵜菊夫, 林秀敏
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGFβによる白色脂肪細胞における脂肪滴蓄積の制御2011
- Author(s)
  楽怡、岡山敦子、野口祐美子、井上靖道、伊藤友香、小野嵜菊夫、斉藤昌之、林秀敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22790078
[Presentation] 薬物代謝酵素UGT1A1タンパク質の安定性制御2011
- Author(s)
  石戸谷その, 伊藤友香, 酒井聡, 水谷隆治, 林秀敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGFβによる白色脂肪細胞における脂肪滴蓄積の制御2011
- Author(s)
  楽怡、岡山敦子、野口祐美子、井上靖道、伊藤友香、小野嵜菊夫、斉藤昌之、林秀敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都府京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22790078
[Presentation] CYP3A4タンパク質の発現制御2011
- Author(s)
  森本真宗, 新開慈子, 伊藤友香, 酒井聡, 水谷隆治, 林秀敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Regulation of FoxO1 activity by TRB12011
- Author(s)
  Y. Noguchi, W. Kojima, S. Sakai, Y. Itoh, Y. Inoue, H. Hayashi
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGF-βinhibits differentiation and accumulation of lipid droplets in white and brown adipocytes2011
- Author(s)
  Yi Yue, Mayumi Inoue, Yumiko Noguchi, Yuka Itoh, Satoshi Sakai, Kikuo Onozaki, Masahiko Saito and Hidetoshi Hayashi
- Organizer
  KEYSTONE SYMPOSIA
- Place of Presentation
  アメリカ合衆国
- Year and Date
  2011-01-14
- Data Source
  KAKENHI-PROJECT-22790078
[Presentation] TGFβによるUGT1A1の転写調節機構の解析2011
- Author(s)
  石井陽子, 中平桂子, 石戸谷その, 伊藤友香, 酒井聡, 水谷隆治, 林秀敏
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGF-βによる白色脂肪細胞における脂肪滴蓄積の制御2011
- Author(s)
  楽怡, 岡山敦子, 野口祐美子, 井上靖道, 伊藤友香, 小野嵜菊夫, 齋藤昌之, 林秀敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGF-β inhibits differentiation and accumulation of lipid droplets in white and brown adipocytes2011
- Author(s)
  Yi Yue, Mayumi Inoue, Yumiko Noguchi, Yuka Itoh, Satoshi Sakai, Kikuo Onozaki, Masahiko Saito, Hidetoshi Hayashi
- Organizer
  keystone symposium Obesity (J2)
- Place of Presentation
  アメリカ合衆国
- Year and Date
  2011-01-14
- Data Source
  KAKENHI-PROJECT-22790078
[Presentation] ストレスセンサータンパク質TRB3とTGF-βシグナルのクロストーク2011
- Author(s)
  牛山小百合, 井手佑子, 吉井由比子, 酒井聡, 伊藤友香, 大岡伸通, 小野嵜菊夫, 井上靖道, 林秀敏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TRB1による糖新生制御分子FoxO1の転写活性増強作用2010
- Author(s)
  小島和香, 酒井聡, 伊藤友香, 林秀敏
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TGF-βによる白色脂肪細胞の脂肪滴消失に伴った遺伝子発現変化2010
- Author(s)
  楽恰, 井上万由美, 野口祐美子, 伊藤友香, 酒井聡, 小野嵜菊夫, 斉藤昌之, 林秀敏
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] 大腸癌由来点変異Smad2L440Rの機能解析および発現制御2010
- Author(s)
  町支優和, 伊藤友香, 井上靖道, 小野嵜菊夫, 林秀敏
- Organizer
  第33回日本分子生物学会年会・第83回生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレス誘導性タンパクTRB3によるTGF-βシグナルの制御2010
- Author(s)
  牛山小百合, 井出佑子, 酒井聡, 伊藤友香, 大岡伸通, 小野嵜菊夫, 林秀敏
- Organizer
  第56回日本薬学会東海支部大会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ストレス誘導性pseudokinase TRB3のヘルパーT細胞分化に及ぼす影響2010
- Author(s)
  松平都和, 西仲駿, 森田陽子, 酒井聡, 伊藤友香, 林秀敏
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ハンチントン病関連遺伝子HAP1の機能解析2010
- Author(s)
  藤井拓夫, 酒井聡, 戸田洋平, 伊藤友香, 篠田晃, 林秀敏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] BMPシグナル伝達分子Smad1の発現制御機構の解析2010
- Author(s)
  岩井俊樹, 伊藤友香, 酒井聡, 高橋佑輔, 井上靖道, 小野嵜菊夫, 林秀敏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] Effects of cytokines on the accumulation of lipid droplets in white and brown adipocytes during their differentiation2009
- Author(s)
  井上万由美, 朴佳栄, 荒川友博, 伊藤友香, 小野嵜菊夫, 斉藤昌之, 林秀敏
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ヒト脳毛細血管内皮細胞におけるカルシウム活性化クロライドチャネルの役割2009
- Author(s)
  波多野紀行,伊藤友香,村木克彦
- Organizer
  平成21年度日本薬学会東海支部例会(D-29)
- Place of Presentation
  四日市
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] ストレス誘導性タンパク質TRB3によるTGF-βシグナルの制御2009
- Author(s)
  牛山小百合, 井手佑子, 酒井聡, 伊藤友香, 大岡伸道, 小野嵜菊夫, 林秀敏
- Organizer
  次世代を担う若手ファーマ・バイオフォーラム2009
- Place of Presentation
  名古屋
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] TRPV4 plays a regulatory role of intracellular Ca2+ in cultured cardiac fibroblasts.2009
- Author(s)
  波多野紀行, 伊藤友香, 村木克彦
- Organizer
  Satellite Symposium of the IUPS2009 "Post-genomic Advances in the Physiology of Smooth Muscle" (P-34)
- Place of Presentation
  Nagoya
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] 滑膜細胞におけるTRPV4による細胞内カルシウム濃度変化とTRPV4活性化薬である4a-phorbol 12,13-didecanoateのサイトカイン産生への影響2009
- Author(s)
  伊藤友香,波多野紀行,鈴木賀央里,武田良文,林秀敏,小野嵜菊夫,廣田耕作,村木克彦
- Organizer
  平成21年度日本薬学会東海支部総会・大会(C-22)
- Place of Presentation
  名古屋
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] 滑膜細胞における浸透圧センサーTRPV4のケモカイン産生に及ぼす影響2009
- Author(s)
  伊藤友香,波多野紀行,林秀敏,小野嵜菊夫,村木克彦
- Organizer
  フォーラム2009:衛生薬学・環境トキシコロジー(P039)
- Place of Presentation
  沖縄
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] ヒト脳毛細血管内皮細胞におけるTRPV4発現機能調節機構の解析2009
- Author(s)
  波多野紀行,伊藤友香,村木克彦
- Organizer
  平成21年度日本薬学会東海支部総会・大会(B-21)
- Place of Presentation
  名古屋
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] A novel regulator of intracellular Ca^<2+> TRPV4 in human synoviocytes.2009
- Author(s)
  Yuka Itoh, Noriyuki Hatano, Hidetoshi Hayashi, Kikuo Onozaki, Katsuhiko Muraki
- Organizer
  Satellite Symposium of the IUPS2009 "Post-genomic Advances in the Physiology of Smooth Muscle" (P-31)
- Place of Presentation
  Nagoya
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] スフィンゴシルホスホリルコリンによる関節リウマチ滑膜細胞死の制御2009
- Author(s)
  伊藤友香,波多野紀行,林秀敏,小野嵜菊夫,村木克彦
- Organizer
  日本薬学会第129年会(27P-pm064)
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] Effects of cytokines on the accumulation of lipid droplets in white and brown adipocytes during their differentiation2009
- Author(s)
  井上万由美, 朴佳栄, 荒川友博, 伊藤友香, 小野嵜菊夫, 斉藤昌之, 林秀敏
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590067
[Presentation] ヒト関節リウマチ滑膜細胞株におけるアセチルコリン受容体の発現とその機能解析2009
- Author(s)
  伊藤友香,鈴木翔太,波多野紀行,林秀敏,小野嵜菊夫,村木克彦
- Organizer
  平成21年度日本薬学会東海支部総会・大会(B-18)
- Place of Presentation
  名古屋
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] スフィンゴシルホスホリルコリンによる関節リウマチ滑膜細胞死の制御2009
- Author(s)
  伊藤友香
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19890238
[Presentation] ラット心線維芽細胞におけるTRP channelを介したCa^<2+>流入2008
- Author(s)
  波多野紀,伊藤友香,村木克彦
- Organizer
  日本薬学会東海支部総会・大会(D-7)
- Place of Presentation
  名古屋
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-20590263
[Presentation] TGF-βシグナル制御因子としてのシュードキナーゼTRB1の機能
- Author(s)
  澤中美希、伊藤友香、井上靖道、林秀敏
- Organizer
  フォーラム2014　衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-26860042

1. MURAKI Katsuhiko (20254310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
2. HATANO Noriyuki (50454319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
3. HAYASHI Hidetoshi (80198853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
4. SAKAI Satoshi (50566081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results

ITOH Yuka 伊藤 友香

Itoh Yuka 伊藤 友香

Research Projects

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Co-Researchers

がん悪性化形質獲得に伴うSmad4機能活性化機構の解明Principal Investigator

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Smad2とSmad cofactorの相互作用によるがん悪性化抑制機構の解明Principal Investigator

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Visualization of the Smad-Smad cofactor cooperativity in cancer progressionPrincipal Investigator

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Molecular mechanism for transcriptional activation by the Smad complexPrincipal Investigator

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Regulation of oncogenic activities by TRB1 through TGF-beta signalingPrincipal Investigator

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Downregulation of lipid droplets formation in adipocyte by TGFβand identification of its regulatorPrincipal Investigator

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Crosstalk between stress and cytokine signaling in metabolic syndrome

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Regulation of expression of vascular cation channels by transcriptional and epigenetical modulation

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Regulation of cell death by HRD1Principal Investigator

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[Journal Article] Receptor-activated transcription factors and beyond: multiple modes of Smad2/3-dependent transmission of TGF-β signaling2024

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[Journal Article] A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation.2019

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[Journal Article] Regulation of Epithelial-Mesenchymal Transition by E3 Ubiquitin Ligases and Deubiquitinase in Cancer2016

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[Journal Article] Tribbles-Related Protein Family Members as Regulators or Substrates of the Ubiquitin-Proteasome System in Cancer Development2016

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[Journal Article] Positive Regulation of Interleukin-2 Expression by a Pseudokinase, Tribbles 1, in Activated T Cells2015

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ITOH Yuka 伊藤友香

Itoh Yuka 伊藤友香