OKUNUKI Yoko 奥貫陽子

Researcher Number	40459508
Affiliation (based on the past Project Information) *help	2013: 東京医科大学, 医学部, 助教 2008 – 2011: Tokyo Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Ophthalmology
Keywords	Principal Investigator 制御性Ｔ細胞 / サイトカイン / 末梢血リンパ球 / Vogt-小柳‐原田病 / 免疫学 / 末梢血リンパ球(PBMC) / 副腎皮質ステロイド / トランスレーショナルリサーチ / IL-17 / Vogt-小柳-原田病 … More / 網膜抗原 / 自己免疫 / ぶどう膜炎 / 自己抗原 / 内因性ぶどう膜炎 / プロテオミクス Less

Vogt-小柳-原田病難治例の治療前判断と予後改善ための免疫学的研究Principal Investigator
- Principal Investigator
  
  奥貫陽子
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical University
Immunological approach to investigate the mechanism of treatment resistant endogenous uveitis and to establish a new treatmentPrincipal Investigator
- Principal Investigator
  
  OKUNUKI Yoko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical University
Proteomic analysis of the disease specific autoantibodies in Behcet's diseasePrincipal Investigator
- Principal Investigator
  
  OKUNUKI Yoko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical University

All 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Costimulatory molecule expression on human uveal melanoma cells : functional analysis of CD40 and B7-H12012
- Author(s)
  Ma J, Usui Y, Kezuka T, Okunuki Y, Zhang L, An X, Mizota, Goto H
- Journal Title
  
  Experimental Eye Research
  
  Volume: 96 Issue: 1 Pages: 98-106
- DOI
  10.1016/j.exer.2011.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Increases of vitreous monocyte chemotactic protein 1 and interleukin 8 levels in patients with concurrent hypertension and diabetic retinopathy2011
- Author(s)
  Okunuki Y, Wakabayashi Y, Usui Y, Kezuka T, Takeuchi M, Iwasaki T, Ohno A, Goto H
- Journal Title
  
  Retina
  
  Volume: 31 Issue: 9 Pages: 1951-1957
- DOI
  10.1097/iae.0b013e31820d3cee
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Relation of intraocular concentrations of inflammatory factors and improvement of macular edema after vitrectomy in branch retinal vein occlusion.2011
- Author(s)
  Okunuki Y, Usui Y, Katai N, Kezuka T, Takeuchi M, Goto H, Wakabayashi Y.
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 151 Pages: 610-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Relation of intraocular concentrations of inflammatory factors and improvement of macular edema after vitrectomy in branch retinal vein occlusion2011
- Author(s)
  Okunuki Y, Usui Y, Katai N, Kezuka T, Takeuchi M, Goto H, Wakabayashi Y
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 151 Pages: 610-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Increases of vitreous monocyte chemotactic protein 1 and interleukin 8 levels in patients with concurrent hypertension and diabetic retinopathy2011
- Author(s)
  Wakabayashi Y, Usui Y, Okunuki Y, Kezuka T, Takeuchi M, Iwasaki T, Ohno A, Goto H
- Journal Title
  
  Retina
  
  Volume: 31 Pages: 1951-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Four cases of bilateral acute retinal necrosis with a long interval after the initial onset2011
- Author(s)
  Okunuki Y, Usui Y, Kezuka T, Takeuchi M, Goto H
- Journal Title
  
  British Journal of Ophthalmology
  
  Volume: 95 Pages: 1251-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Four cases of bilateral acute retinal necrosis with a long interval after the initial onset.2011
- Author(s)
  Okunuki Y, Usui Y, Kezuka T, Takeuchi M, Goto H.
- Journal Title
  
  British Journal of Ophthalmology
  
  Volume: (ePub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Correlation of vascular endothelial growth factor with chemokines in the vitreous in diabetic retinopathy2010
- Author(s)
  Wakabayashi Y, Usui Y, Okunuki Y, Kezuka T, Takeuchi M, Goto H, Iwasaki T
- Journal Title
  
  Retina
  
  Volume: 30 Pages: 339-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791696
[Journal Article] Effect of dioxin on vascular endothelial growth factor (VEGF) production in the retina associated with choroidal neovascularization.2009
- Author(s)
  Takeuci A, Okunuki Y, et al
- Journal Title
  
  Investigative Ophthalmology and Visual Science 50
  
  Pages: 3410-4316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Functional and morphological changes in the eyes of Bechcet's patients with uveitis.2009
- Author(s)
  Takeuchi M, Okunuki Y, et al
- Journal Title
  
  Acta Ophthalmologica Jun 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Suppression of experimental autoimmume uveoretinitis by regulatory dendritic cells in mice.2009
- Author(s)
  Usui Y, Okunuki Y, et al
- Journal Title
  
  Archives of Ophthalmology 127
  
  Pages: 514-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] 制御性樹状細胞を用いた実験的自己免疫性ぶどう膜網膜炎の抑制2009
- Author(s)
  臼井嘉彦、奥貫陽子, ら
- Journal Title
  
  日本眼科学会雑誌 113
  
  Pages: 819-819
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Angiotensin 2 type 1 receptor blocker telmisartan suppress experimenta ; autoimmune uveitis2009
- Author(s)
  Okunuki Y, et.al.
- Journal Title
  
  Investigative Opththalmology and Visual Sicence (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Immune responses to interphotoreceptor retinoid-binding protein and S-antigen in Behcet's patients with uveitis.2009
- Author(s)
  Takeuchi M, Okunuki Y, et al
- Journal Title
  
  Investigative Ophthalmology and Visual Science Jan 20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Human iris pigment epithelial cels suppress T-cell activation viadireact cell contact.2009
- Author(s)
  Hattori T, Okunuki Y, et al
- Journal Title
  
  Experimental Eye Research
  
  Pages: 358-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Dioxin promotes vascular endothelial growth factor production in the retina and enhances choroidal neovascularization2009
- Author(s)
  Takeuchi A, Okunuki Y, et.al.
- Journal Title
  
  Investigative Opththalmology and Visual Sicence (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Suppression of experimental autoimmue uveitis by angiotensin II type l receptor blocker telmisartan.2009
- Author(s)
  Okunuki Y, et al
- Journal Title
  
  Investigative Ophthalmology and Visual Science 50
  
  Pages: 2255-2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Correlation of vascular endothelial growth factor with chemokiens in the vitreous in diabetic retinopathy.2009
- Author(s)
  Okunuki Y, et al
- Journal Title
  
  Retina 30
  
  Pages: 339-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Proteomic surveillance of retinal autoantigens in endogenous uveitis:implication of Esterase D and brain-type creatine kinase as novel autoantigens.2008
- Author(s)
  Okunuki Y, et al
- Journal Title
  
  Molecular Vision 12巻
  
  Pages: 1094-1104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Proteomic surveillance of retinal autoantigens in endogeous uveitis : implication of esteraseD and brain-type creatine kinase as novel autoantigens2008
- Author(s)
  Okunuki Y., et.al.
- Journal Title
  
  Molecular Vision 14
  
  Pages: 1094-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Journal Article] Increased levels of monokine induced by interferon-gamma (Mig) in the vitreous of patients of diabetic retinopathy2008
- Author(s)
  Okunuki Y., et.al.
- Journal Title
  
  Diabetic Medicine 25
  
  Pages: 875-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] Vogt-小柳-原田病の慢性化に関与する因子の解析2013
- Author(s)
  奥貫　陽子
- Organizer
  第４７回　眼炎症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25462761
[Presentation] Analysis of prognostic factors in Vogt-Koyanagai-Harada disease2013
- Author(s)
  奥貫　陽子
- Organizer
  American Associate of Ophthalmology 2013
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-25462761
[Presentation] Vogt-小柳-原田病の慢性化と急性期眼外症状の関連2013
- Author(s)
  奥貫　陽子
- Organizer
  第67回日本臨床眼科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25462761
[Presentation] Vogt-小柳-原田病の発症時年齢および性別と臨床像に関する検討2012
- Author(s)
  奥貫陽子、臼井嘉彦、毛塚剛司、後藤浩
- Organizer
  116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791696
[Presentation] Cytokine analysis and visual prognosis of Vogt-Koyanagi-Harada disease2011
- Author(s)
  奥貫陽子
- Organizer
  The 11^<th> international ocular inflammation society congress and international assembly of ocular inflammation society
- Place of Presentation
  インド、ゴア
- Data Source
  KAKENHI-PROJECT-22791696
[Presentation] Cytokine analysis and visual prognosis of Vogt-Koyanagi-Harada disease2011
- Author(s)
  Yoko Okunuki
- Organizer
  The 11th international ocular inflammation society congress and international assembly of ocular inflammation society
- Place of Presentation
  インド
- Data Source
  KAKENHI-PROJECT-22791696
[Presentation] Cytokine analysis to estimate the disease activity in Vogt-Koyanagi-Harada disease patients2010
- Author(s)
  Yoko Okunuki, Yoshihiko Usui, Takeshi Kezuka, Masaru Takeuchi, Hiroshi Goto
- Organizer
  ARVO 2010
- Place of Presentation
  アメリカ、フロリダ州
- Data Source
  KAKENHI-PROJECT-22791696
[Presentation] Cytokine analysis to estimate the disease activity2010
- Author(s)
  Yoko Okunuki, Yoshihiko Usui, Takeshi Kezuka, Masaru Takeuchi, Hiroshi Goto
- Organizer
  Vogt-Koyanagi-Harada disease patients ARVO2010
- Place of Presentation
  フロリダ
- Data Source
  KAKENHI-PROJECT-22791696
[Presentation] Vogt-小柳-原田病患者の末梢血単核球IL-17産生とステロイド治療に対する反応の検討2010
- Author(s)
  奥貫陽子、臼井嘉彦、毛塚剛司、竹内大、後藤浩
- Organizer
  第114回日本眼科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22791696
[Presentation] Analysis of multiple chemokines and growth factors in the vitreous af patients with branch retinal vein occlusion.2009
- Author(s)
  Okunuki Y, et al
- Organizer
  Asssociation for research and in vision and ophthalmology
- Place of Presentation
  アメリカフロリダ州
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] Vogt-小柳原田病患者の末梢血単核球サイトカイン産生とステロイド治療効果との関連2009
- Author(s)
  奥貫陽子, ら
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] 網膜血管に異常を認めたAccute outer retinopathyの1例2009
- Author(s)
  奥貫陽子, ら
- Organizer
  第48回網膜硝子体学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] 先発眼から長期経過後に瞭眼に発症した急性網膜壊死の4例2009
- Author(s)
  奥貫陽子, ら
- Organizer
  第43回眼炎症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] Cytokine analysis to estimate the effect of corticosteroid in Vogt-Koyanagi-Harada disease patients2009
- Author(s)
  Okunuki Y, et.al.
- Organizer
  6^<th> international workshop on Vogt-Koyanagi-Harada Disease and Sympathetic Ophthalmia
- Place of Presentation
  シンガポール
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] 免疫原性を有する網膜局在タンパクのプロテオーム解析2008
- Author(s)
  奥貫陽子、竹内大, ら
- Organizer
  東京医科大学ハイテクリサーチセンター最終研究成果
- Place of Presentation
  公開シンポジウム
- Year and Date
  2008-01-21
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] Suppression of experimental autoimmne uveoretinitis by blocking angiotensin 2 type 1 receptor2008
- Author(s)
  Okunuki Y, et.al.
- Organizer
  Association for Reseach in Vision and Ophthalmology
- Place of Presentation
  アメリカ、フロリダ州
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] 実験的自己免疫性ぶどう膜網膜炎における肥満細胞の役割2008
- Author(s)
  奥貫陽子, ら
- Organizer
  第161回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] 網膜静脈分子閉塞症における硝子体中ケモカイン・サイトカインの解析2008
- Author(s)
  奥貫陽子, ら
- Organizer
  第112回日本眼科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20791279
[Presentation] 網膜中心静脈閉塞症様所見を呈した非肉芽腫性虹彩毛様体炎の2例2008
- Author(s)
  奥貫陽子, ら
- Organizer
  第62回日本臨床眼科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20791279

1. 毛塚剛司 (00287137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKUNUKI Yoko 奥貫 陽子

Research Projects

Research Products

Co-Researchers

Vogt-小柳-原田病難治例の治療前判断と予後改善ための免疫学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological approach to investigate the mechanism of treatment resistant endogenous uveitis and to establish a new treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomic analysis of the disease specific autoantibodies in Behcet's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Costimulatory molecule expression on human uveal melanoma cells : functional analysis of CD40 and B7-H12012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increases of vitreous monocyte chemotactic protein 1 and interleukin 8 levels in patients with concurrent hypertension and diabetic retinopathy2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relation of intraocular concentrations of inflammatory factors and improvement of macular edema after vitrectomy in branch retinal vein occlusion.2011

Author(s)

Journal Title

Data Source

[Journal Article] Relation of intraocular concentrations of inflammatory factors and improvement of macular edema after vitrectomy in branch retinal vein occlusion2011

Author(s)

Journal Title

Data Source

[Journal Article] Increases of vitreous monocyte chemotactic protein 1 and interleukin 8 levels in patients with concurrent hypertension and diabetic retinopathy2011

Author(s)

Journal Title

Data Source

[Journal Article] Four cases of bilateral acute retinal necrosis with a long interval after the initial onset2011

Author(s)

Journal Title

Data Source

[Journal Article] Four cases of bilateral acute retinal necrosis with a long interval after the initial onset.2011

Author(s)

Journal Title

Data Source

[Journal Article] Correlation of vascular endothelial growth factor with chemokines in the vitreous in diabetic retinopathy2010

Author(s)

Journal Title

Data Source

[Journal Article] Effect of dioxin on vascular endothelial growth factor (VEGF) production in the retina associated with choroidal neovascularization.2009

Author(s)

Journal Title

Data Source

[Journal Article] Functional and morphological changes in the eyes of Bechcet's patients with uveitis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of experimental autoimmume uveoretinitis by regulatory dendritic cells in mice.2009

Author(s)

Journal Title

Data Source

[Journal Article] 制御性樹状細胞を用いた実験的自己免疫性ぶどう膜網膜炎の抑制2009

Author(s)

Journal Title

Data Source

[Journal Article] Angiotensin 2 type 1 receptor blocker telmisartan suppress experimenta ; autoimmune uveitis2009

Author(s)

Journal Title

Data Source

[Journal Article] Immune responses to interphotoreceptor retinoid-binding protein and S-antigen in Behcet's patients with uveitis.2009

Author(s)

Journal Title

Data Source

OKUNUKI Yoko 奥貫陽子

[Presentation] Vogt-小柳-原田病の慢性化と急性期眼外症状の関連2013