Nakamura Yukihiro 中村行宏

… Alternative Names

中村行宏ナカムラユキヒロ

NAKAMURA Yukihiro 中村行宏

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Researcher Number	40460696
Other IDs	https://orcid.org/0000-0002-8820-7780
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京慈恵会医科大学, 医学部, 講師 2017 – 2019: 東京慈恵会医科大学, 医学部, 講師 2011 – 2012: 同志社大学, 研究開発推進機構, 研究員 2009: Doshisha University, 研究開発推進機構, 研究員 2008 – 2009: Doshisha University, 研究開発機構, 嘱託研究員
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience / Neurophysiology and muscle physiology / Neurophysiology and muscle physiology Except Principal Investigator Basic Section 46010:Neuroscience-general-related / Basic Section 56050:Otorhinolaryngology-related / Basic Section 46030:Function of nervous system-related
Keywords	Principal Investigator シナプス伝達 / カルシウムチャネル / シナプス / Held萼状シナプス / シナプス前終末 / シナプス前末端 / 生理学 / 脳・神経 / 神経回路 / ニューロン … More / カルシウムイメージング / カルシウム / 平行線維 / 神経伝達物質 / シグナル伝達 / 神経伝達物質放出 / シミュレーション / 開口放出 / パッチクランプ / カルシウムキレート剤 / 短期可塑性 / シナプス小胞 / 国際研究者交流 / 共焦点顕微鏡 / Caチャネル / 神経科学 / プレシナプス … More Except Principal Investigator カルシウム / 線条体 / 加齢 / アセチルコリン / Cochlear synaptopathy / 薬剤性難聴 / シナプス / 有毛細胞 / 蝸牛 / グルタミン酸イメージング / カルシウムイメージング / パッチクランプ法 / 神経伝達物質放出 / シナプス伝達 Less

Pathophysiological study of cochlear synaptopathy in drug-induced hearing loss
- Principal Investigator
  
  鷹合秀輝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
発達・加齢によるコリン作動性神経伝達の変化メカニズムの解明
- Principal Investigator
  
  鈴木江津子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Jikei University School of Medicine
Study on the spatio-temporal dynamics of calcium and glutamate coupling at sensory ribbon synapses.
- Principal Investigator
  
  大島知子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  The University of Tokyo
Elucidation of Ca sparks in CNS presynaptic terminalsPrincipal Investigator
- Principal Investigator
  
  中村行宏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Jikei University School of Medicine
Spatial distribution of readily releasable vesicles underlying short-term plasticity at synapsesPrincipal Investigator
- Principal Investigator
  
  Nakamura Yukihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Jikei University School of Medicine
Developmental changes in Ca channel density and single channel conductance at the presynaptic terminal of central nervous systemPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Yukihiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Doshisha University
Developmental changes in calcium domain at the presynaptic terminal of the central synapsePrincipal Investigator
- Principal Investigator
  
  NAKAMURA Yukihiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Doshisha University

All 2024 2023 2019 2018 2017 2012 2011 2009 Other

All Journal Article Presentation Book

[Book] Patch Clamp Techniques: From Beginning to Advanced Protocols2012
- Author(s)
  高橋智幸,堀哲也,中村行宏,山下貴之(共著)
- Publisher
  Springer,岡田泰伸編
- Data Source
  KAKENHI-PROJECT-23700474
[Book] 最新パッチクランプ実験法2011
- Author(s)
  高橋智幸,堀哲也,中村行宏,山下貴之(共著)
- Publisher
  吉岡書店,岡田泰伸編
- Data Source
  KAKENHI-PROJECT-23700474
[Journal Article] GABAB receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles2024
- Author(s)
  Koppensteiner Peter、Bhandari Pradeep、Onal Cihan、Borges-Merjane Carolina、Le Monnier Elodie、Roy Utsa、Nakamura Yukihiro、Sadakata Tetsushi、Sanbo Makoto、Hirabayashi Masumi、Rhee JeongSeop、Brose Nils、Jonas Peter、Shigemoto Ryuichi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 8 Pages: 2301449121-2301449121
- DOI
  10.1073/pnas.2301449121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06398
[Journal Article] Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules2019
- Author(s)
  Adam Fekete, Yukihiro Nakamura, Yi-Mei Yang, Stefan Herlitze, Melanie D. Mark, David A. DiGregorio, Lu-Yang Wang
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 826-826
- DOI
  10.1038/s41467-019-08452-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07064
[Journal Article] Ataxic phenotype with altered CaV3.1 channel property in a mouse model for spinocerebellar ataxia 422019
- Author(s)
  Hashiguchi S, Doi H, Kunii M, Nakamura Y, Shimuta M, （32名略） Ishikawa T, Tanaka F
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 130 Pages: 104516-104516
- DOI
  10.1016/j.nbd.2019.104516
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06529, KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-18K07504, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-19K17014, KAKENHI-PUBLICLY-18H04937, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-17K07064, KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-18K15460
[Journal Article] EGTA Can Inhibit Vesicular Release in the Nanodomain of Single Ca2+ Channels2019
- Author(s)
  Nakamura Yukihiro
- Journal Title
  
  Frontiers in Synaptic Neuroscience
  
  Volume: 11
- DOI
  10.3389/fnsyn.2019.00026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07064
[Journal Article] Variations in Ca2+ influx can alter Ca2+-chelator-based estimates of Ca2+ channel-synaptic vesicle coupling distance2018
- Author(s)
  Yukihiro Nakamura, Maria Reva, David A. DiGregorio
- Journal Title
  
  Journal of Neuroscience
  
  Volume: early release Issue: 16 Pages: 3971-3987
- DOI
  10.1523/jneurosci.2061-17.2018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07064
[Journal Article] Two-component latency distributions indicate two-step vesicular release at simple glutamatergic synapses2018
- Author(s)
  Takafumi Miki, Yukihiro Nakamura, Gerardo Malagon, Erwin Neher, Alain Marty Alain
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3943-3943
- DOI
  10.1038/s41467-018-06336-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07064, KAKENHI-PROJECT-18K06472
[Presentation] Ca channel-release coupling in presynaptic terminals of the developing sensory system2024
- Author(s)
  Yukihiro Nakamura
- Organizer
  Neuroscience Symposium "The past and the future of synaptic physiology"
- Data Source
  KAKENHI-PROJECT-21K06398
[Presentation] Visualizing the spatiotemporal dynamics of glutamate release from ribbon-associated and ribbon free active zones in the goldfish retinal bipolar cell terminal2023
- Author(s)
  Tomoko Oshima-Takago, Hirokazu Sakamoto, Yukihiro Nakamura, Shigeyuki Namiki, Kenzo Hirose, Masao Tachibana, Hideki Takago
- Organizer
  11th World Congress of Neuroscience IBRO 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06398
[Presentation] 脊髄小脳失調症42型モデルマウスを用いた神経変性分子病態基盤の解明2019
- Author(s)
  橋口俊太, 土井宏, 國井美紗子, 中村行宏, 志牟田美佐, 鈴木江津子, 大久保正紀, 笹岡俊邦, 竹内英之, 石川太郎, 田中章景
- Organizer
  Neuro2019（第42回日本神経科学大会第62回日本神経化学大会）
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] EGTA can inhibit vesicular release in the 'nanodomain' distance from Ca channels2019
- Author(s)
  Nakamura Yukihiro
- Organizer
  10th IBRO Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] Ataxic phenotype with altered CaV3.1 channel property in a mouse model for spinocerebellar ataxia 422019
- Author(s)
  Doi H, Hashiguchi S, Kunii M, Nakamura Y, Shimuta M, Ssuzuki E, Okubo M, Sasaoka T, Takeuchi H, Ishikawa T, Tanaka F
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] 中枢神経シナプス前末端における即時放出可能小胞の包括的分布の推定2018
- Author(s)
  中村行宏, 堀哲也
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] Linearized buffer approximationとreaction-diffusion simulationによるCa濃度勾配の推定の比較2018
- Author(s)
  中村行宏, David DiGregorio
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] Linearized buffer approximationtionとreaction-diffusion simulationによるCa濃度勾配の推定の比較2018
- Author(s)
  中村行宏, David A. DiGregorio
- Organizer
  第42回日本神経科学会大会
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] Cav2.1 changes its number and distribution pattern after stimulation in cerebellar parallel fibre-Purkinje cell synapses2017
- Author(s)
  HARADA H. NAKAMURA Y, BEPPU K,MATSUI K, WATANABE M, SAKAMOTO H,NAMIKI S, HIROSE K, SHIGEMOTO R.
- Organizer
  Neuro2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] Cav2.1 changes its number and distribution pattern after stimulation in cerebellar parallel fibre-Purkinje cell synapses2017
- Author(s)
  原田春美, 中村行宏, 別府薫, 松井広, 渡辺雅彦, 坂本寛和, 並木繁行, 廣瀬謙造, 重本隆一
- Organizer
  第40回日本神経科学会大会
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] EGTAによるナノドメインCaの抑制2017
- Author(s)
  中村行宏, 堀哲也
- Organizer
  第40回日本神経科学会大会
- Data Source
  KAKENHI-PROJECT-17K07064
[Presentation] Developmental changes in presynaptic Ca signaling at the calyx of Held2012
- Author(s)
  中村行宏
- Organizer
  国際シンポジウム”Physical Concepts of Medical Science”
- Place of Presentation
  台湾・高雄
- Invited
- Data Source
  KAKENHI-PROJECT-23700474
[Presentation] Developmental changes in presynaptic Ca signaling at the calyx of Held2012
- Author(s)
  中村行宏
- Organizer
  高雄醫學大學国際シンポジウム"Physical Concepts of Medical Science
- Place of Presentation
  高雄台湾
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23700474
[Presentation] 成熟した中枢神経において多数のCaチャネルによって媒介される速いシナプス伝達2012
- Author(s)
  中村行宏, 原田春美, 釜澤直美, 松井広, 重本隆一, Jason Rothman, Angus Silver, David DiGregorio, 高橋智幸
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23700474
[Presentation] Developmental changes in spatial profiles of Ca2+ channel and Ca2+ influx underlying tightening of Ca2+-secretion coupling at the calyx of Held2012
- Author(s)
  中村行宏, 原田春美, 釜澤直美, 松井広, 重本隆一, Jason Rothman, Angus Silver, David DiGregorio, 高橋智幸
- Organizer
  Conferences Jacques-Monod"Imaging neuronal functions: from molecules to circuits
- Place of Presentation
  Roscoff フランス
- Year and Date
  2012-07-02
- Data Source
  KAKENHI-PROJECT-23700474
[Presentation] Developmental changes in spatial profiles of Ca channel and Ca influx underlying tightening of Ca-secretion coupling at the calyx of Held2012
- Author(s)
  中村行宏
- Organizer
  Conferences Jacques-Monod “Imaging neuronal functions: from molecules to circuits”
- Place of Presentation
  フランス・ロスコフ
- Data Source
  KAKENHI-PROJECT-23700474
[Presentation] Developmental changes in the spatial distribution of Ca2+ signals at the calyx of Held2011
- Author(s)
  中村行宏, David A.DiGregorio, 高橋智幸
- Organizer
  OIST International Workshop "Molecular & Structural Organization of Presynaptic Function and Plasticity"
- Place of Presentation
  沖縄恩納村
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23700474
[Presentation] Developmental reduction in functional Ca^<2+> channel density tightens Ca^<2+>-secretion coupling at a central excitatory synapse2009
- Author(s)
  中村行宏 et al.
- Organizer
  2009 Annual Meeting of Society for Neuroscience
- Place of Presentation
  シカゴ
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20700351
[Presentation] シナプス前終末における伝達物質放出機構-Ca結合の生後発達変化2009
- Author(s)
  中村行宏, 他
- Organizer
  生理学研究所研究会「シナプス伝達の概念指向型研究」
- Place of Presentation
  生理学研究所(岡崎市)
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20700351
[Presentation] Developmental reduction in functional Ca2+ channel density tightens Ca2+-secretion coupling at a central excitatory synapse.2009
- Author(s)
  Nakamura Y, Silver RA, DiGregorio DA, Takahashi T
- Organizer
  he Society for Neuroscience 39th Annual Meeting.
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20700351
[Presentation] シナプス前終末における伝達物質放出機構-Ca結合の生後発達変化2009
- Author(s)
  中村行宏, Silver RA, DiGregorio DA, 高橋智幸
- Organizer
  生理学研究所研究会『シナプス伝達の概念指向型研究』
- Place of Presentation
  岡崎市
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20700351
[Presentation] Developmental changes in the spatial distribution of Ca2+ signals at the calyx of Held
- Author(s)
  Yukihiro Nakamura, David A.DiGregorio, Tomoyuki Takahashi
- Organizer
  OIST International Workshop "Molecular & Structural Organization of Presynaptic Function and Plasticity"
- Place of Presentation
  沖縄科学技術研究基盤整備機構（沖縄）
- Data Source
  KAKENHI-PROJECT-23700474

1. 鷹合秀輝 (70401354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 大島知子 (50731783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鈴木江津子 (60424313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIKAWA Taro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 志牟田美佐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Yukihiro 中村 行宏

中村 行宏 ナカムラ ユキヒロ

NAKAMURA Yukihiro 中村 行宏

Research Projects

Research Products

Co-Researchers

Pathophysiological study of cochlear synaptopathy in drug-induced hearing loss

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

発達・加齢によるコリン作動性神経伝達の変化メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the spatio-temporal dynamics of calcium and glutamate coupling at sensory ribbon synapses.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Ca sparks in CNS presynaptic terminalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Spatial distribution of readily releasable vesicles underlying short-term plasticity at synapsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Developmental changes in Ca channel density and single channel conductance at the presynaptic terminal of central nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Developmental changes in calcium domain at the presynaptic terminal of the central synapsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Patch Clamp Techniques: From Beginning to Advanced Protocols2012

Author(s)

Publisher

Data Source

[Book] 最新パッチクランプ実験法2011

Author(s)

Publisher

Data Source

[Journal Article] GABAB receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ataxic phenotype with altered CaV3.1 channel property in a mouse model for spinocerebellar ataxia 422019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EGTA Can Inhibit Vesicular Release in the Nanodomain of Single Ca2+ Channels2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variations in Ca2+ influx can alter Ca2+-chelator-based estimates of Ca2+ channel-synaptic vesicle coupling distance2018

Author(s)

Journal Title

DOI

Nakamura Yukihiro 中村行宏

中村行宏ナカムラユキヒロ

NAKAMURA Yukihiro 中村行宏