Fujita Takayuki 藤田孝之

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FUJITA Takayuki 藤田孝之

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Researcher Number	40468202
Other IDs
Affiliation (Current)	2025: 福岡大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 福岡大学, 医学部, 教授 2018 – 2020: 横浜市立大学, 医学部, 講師 2012 – 2016: 横浜市立大学, 医学部, 講師 2009 – 2011: 横浜市立大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / General physiology / Circulatory organs internal medicine Except Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Complex Systems Disease Theory / Circulatory organs internal medicine / Complex systems
Keywords	Principal Investigator 交感神経 / 心疾患 / EPAC / Epac / 不整脈 / 循環器疾患 / ｃAMP / 高血圧 / p53 / 分子心臓病態学 / cAMP / 動脈硬化 … More Except Principal Investigator … More 幹細胞 / 加齢 / 免疫 / 炎症 / 心筋梗塞 / 評価 / 再生 / 間葉系幹細胞 / 心機能制御 / 交感神経 / カルシウム / cAMP / 心臓 / 組織再生 / 栄養 / 心疾患 / 運動 / 数理モデル / 不整脈 / アデニル酸シクラーゼ / 心筋細胞 / ｃＡＭＰ / 分子 / カテコラミン / 自律神経 / 機能制御 / セカンドメッセンジャー / 循環器・高血圧 / 生理学 / シグナル伝達 Less

交感神経の有害シグナルの選択的抑制による、より安全で有効な心疾患治療戦略の開発Principal Investigator
- Principal Investigator
  
  藤田孝之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Fukuoka University
Effects of nutrition, aging, and stem cell against inflammation on high-risk heart disease, and evaluation of tissue regeneration ability.
- Principal Investigator
  
  千葉由美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Yokohama City University
The usefulness of an AC5 inhibitor metabolite in the treatment of arrhythmias.Principal Investigator
- Principal Investigator
  
  Fujita Takayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Fukuoka University
  Yokohama City University
How to predict the collapse of homeostasis in circulatory regulation
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Yokohama City University
Evaluation of effects on age and tissue regeneration by exercise intervention on high-risk myocardial infarction
- Principal Investigator
  
  CHIBA Yumi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Yokohama City University
The role of Epac in the development of arteriosclerosisPrincipal Investigator
- Principal Investigator
  
  Fujita Takayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yokohama City University
The role of EPAC in development of hypertensionPrincipal Investigator
- Principal Investigator
  
  FUJITA Takayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yokohama City University
Molecular regulation of cardiac function by the automatic nervous system
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
Integration of the regulation of cardiac myocyte signal pathway and neuro hormonal regulation
- Principal Investigator
  
  ISHIKAWA YOSHIHIRO
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Yokohama City University
Fortilin, a novel p53 inhibiting protein, in cardiovascular system.Principal Investigator
- Principal Investigator
  
  FUJITA Takayuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University

All 2023 2021 2020 2019 2018 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Patent Other

[Journal Article] The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis.2023
- Author(s)
  Yaopeng Hu, Jiehui Cang, Keizo Hiraishi, Takayuki Fujita, and Ryuji Inoue
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24(14) Issue: 14 Pages: 11798-11798
- DOI
  10.3390/ijms241411798
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19659, KAKENHI-PROJECT-20K07269, KAKENHI-PROJECT-20K16126
[Journal Article] Diagnostic potential of serum extracellular vesicles expressing prostate-specific membrane antigen in urologic malignancies.2021
- Author(s)
  Kawakami, K. Fujita, Y. Kato, T. Horie, K. Koie, T. Umezawa, K. Tsumoto, H. Miura, Y. Katagiri, Y. Miyazaki, T. Ohsawa, I. Mizutani, K. Ito, M.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 15000-15000
- DOI
  10.1038/s41598-021-94603-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07478, KAKENHI-PROJECT-20H04136, KAKENHI-PROJECT-20K07817, KAKENHI-PROJECT-20K11664, KAKENHI-PROJECT-21K19659
[Journal Article] Excessive EP4 signaling in smooth muscle cells induces abdominal aortic aneurysm by amplifying inflammation2020
- Author(s)
  Hiromi T, Yokoyama U, Kurotaki D, Mamun A, Ishiwata R, Ichikawa Y, Nishihara H, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Takeuchi I, Masuda M, Breyer M, Tamura T, and Ishikawa Y
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 40 Issue: 6 Pages: 1559-1573
- DOI
  10.1161/atvbaha.120.314297
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-20K21638, KAKENHI-PROJECT-19K16510, KAKENHI-PROJECT-20H03650, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-19H03657, KAKENHI-PROJECT-18KT0073
[Journal Article] Fibulin-1 Integrates Subendothelial Extracellular Matrices and Contributes to Anatomical Closure of the Ductus Arteriosus.2020
- Author(s)
  Ito S, Yokoyama U, Nakakoji T, Cooley MA, Sasaki T, Hatano S, Kato Y, Saito J, Nicho N, Iwasaki S, Umemura M, Fujita T, Masuda M, Asou T, and Ishikawa Y
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 40 Issue: 9 Pages: 2212-2226
- DOI
  10.1161/atvbaha.120.314729
- NAID
  130008001539
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21638, KAKENHI-PROJECT-20K16861, KAKENHI-PROJECT-20H03650, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-19H03657, KAKENHI-PROJECT-18KT0073
[Journal Article] Correction to: Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.2019
- Author(s)
  Jin H, Fujita T, Jin M, Kurotani R, Hidaka Y, Cai W, Suita K, Prajapati R, Liang C, Ohnuki Y, Mototani Y, Umemura M, Yokoyama U, Sato M, Okumura S, Ishikawa Y.
- Journal Title
  
  J Physiol Sci.
  
  Volume: - Issue: 3 Pages: 557-557
- DOI
  10.1007/s12576-019-00661-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08138, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K15560, KAKENHI-PROJECT-19H03657
[Journal Article] Translationally controlled tumor protein (TCTP) plays a pivotal role in cardiomyocyte survival through a Bnip3-dependent mechanism.2019
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, Suita K, Shigeta M, Kiyonari H, Umemura M, Yokoyama U, Sadoshima J, Ishikawa Y.
- Journal Title
  
  Cell Death Dis
  
  Volume: 10 Issue: 8 Pages: 549-549
- DOI
  10.1038/s41419-019-1787-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-19H03657
[Journal Article] Doxorubicin induces trans-differentiation and MMP1 expression in cardiac fibroblasts via cell death-independent pathways.2019
- Author(s)
  Narikawa M, Umemura M, Tanaka R, Hikichi M, Nagasako A, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 14 Issue: 9 Pages: e0221940-e0221940
- DOI
  10.1371/journal.pone.0221940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-19H03657
[Journal Article] Prostaglandin E2 receptor EP4 regulates cell migration through Orai1.2019
- Author(s)
  Osawa K, Umemura M, Nakakaji R, Tanaka R, Islam RM, Nagasako A, Fujita T, Yokoyama U, Koizumi T, Mitsudo K, Ishikawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 1 Pages: 160-174
- DOI
  10.1111/cas.14247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-17K11882
[Journal Article] Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-2019
- Author(s)
  Prajapati R, Fujita T, Suita K, Nakamura T, Cai W, Hidaka Y, Umemura M, Yokoyama U, Knollmann BC, Okumura S, Ishikawa Y.
- Journal Title
  
  Circ J.
  
  Volume: 83 Pages: 295-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KT0073
[Journal Article] Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice2019
- Author(s)
  Prajapati R, Fujita T, Suita K, Nakamura T, Cai W, Hidaka Y, Umemura M, Yokoyama U, Knollmann BC, Okumura S, Ishikawa Y
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 2 Pages: 295-303
- DOI
  10.1253/circj.CJ-18-0743
- NAID
  130007557004
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-17K15560, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-18K15013
[Journal Article] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration2019
- Author(s)
  Yuko Kato, Utako Yokoyama, Takayuki Fujita, Masanari Umemura, Tetsuo Kubota, Yoshihiro Ishikawa
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 69 Issue: 2 Pages: 175-184
- DOI
  10.1007/s12576-018-0631-7
- NAID
  40021818894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08976, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-18KT0073
[Journal Article] Reactive fibrosis precedes doxorubicin-induced heart failure through sterile inflammation.2019
- Author(s)
  Tanaka R, Umemura M, Narikawa M, Hikichi M, Osaw K, Fujita T, Yokoyama U, Ishigami T, Tamura K, Ishikawa Y.
- Journal Title
  
  ESC Heart Fail.
  
  Volume: 7 Issue: 2 Pages: 588-603
- DOI
  10.1002/ehf2.12616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-19H03657
[Journal Article] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced arrhythmias without adverse effect on heart function in mice2018
- Author(s)
  Suita Kenji、Fujita Takayuki、Cai Wenqian、Hidaka Yuko、Jin Huiling、Prajapati Rajesh、Umemura Masanari、Yokoyama Utako、Sato Motohiko、Knollmann Bj?rn C.、Okumura Satoshi、Ishikawa Yoshihiro
- Journal Title
  
  Pfl?gers Archiv - European Journal of Physiology
  
  Volume: 未定 Issue: 6 Pages: 923-935
- DOI
  10.1007/s00424-018-2121-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-17K01828, KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] Alternating magnetic field (AMF) enhances cytotoxicity of compound c.2018
- Author(s)
  Akimoto T, Umemura M, Nagasako A, Ohtake M, Fujita T, Yokoyama U, Eguchi H, Yamamoto T, Ishikawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 11 Pages: 3483-3493
- DOI
  10.1111/cas.13781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-18K16592, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] Tissue-type plasminogen activator contributes to remodeling of the rat ductus arteriosus.2018
- Author(s)
  Saito J, Yokoyama U, Nicho N, Zheng YW, Ichikawa Y, Ito S, Umemura M, Fujita T, Ito S, Taniguchi H, Asou T, Masuda M, Ishikawa Y.
- Journal Title
  
  PLoS One
  
  Volume: 13(1) Issue: 1 Pages: e0190871-e0190871
- DOI
  10.1371/journal.pone.0190871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16276, KAKENHI-PROJECT-16H07107, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-15H05761
[Journal Article] Treatment of oral cancer using magnetized paclitaxel2018
- Author(s)
  Nakakaji Rina、Umemura Masanari、Mitsudo Kenji、Kim Jeong-Hwan、Hoshino Yujiro、Sato Itaru、Masuda Takatsugu、Yamamoto Masahiro、Kioi Mitomu、Koizumi Toshiyuki、Fujita Takayuki、Yokoyama Utako、Iida Masaki、Sato Motohiko、以下7名
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 21 Pages: 15591-15605
- DOI
  10.18632/oncotarget.24570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-26463053, KAKENHI-PROJECT-18K05307, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K11730, KAKENHI-PROJECT-15H05761
[Journal Article] Acute hyperthermia inhibits TGF-β1-induced cardiac fibroblast activation via uppression of Akt Signaling.2018
- Author(s)
  Narikawa M, Umemura M, Tanaka R, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 6277-6277
- DOI
  10.1038/s41598-018-24749-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-17K09730
[Journal Article] Hydrostatic pressure suppressed fibrotic change via Akt/GSK-3 signaling in human cardiac fibroblasts.2018
- Author(s)
  Tanaka R, Umemura M, Narikawa M, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 6 Issue: 9 Pages: e13687-e13687
- DOI
  10.14814/phy2.13687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-17K09730
[Journal Article] A selective antagonist of prostaglandin E receptor subtype 4 attenuates abdominal aortic aneurysm.2018
- Author(s)
  Mamun A, Yokoyama U, Saito J, Ito S, Hiromi T, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Masuda M, Ishikawa Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 6 Issue: 18
- DOI
  10.14814/phy2.13878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.2016
- Author(s)
  Jin H，Fujita T，Jin M，Kurotani R，Hidaka Y，Cai W，Suita K，Prajapati R，Liang C，Ohnuki Y，Mototani Y，Umemura M，Yokoyama U，Sato M，Okumura S，Ishikawa Y.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 印刷中 Issue: 1 Pages: 77-87
- DOI
  10.1007/s12576-016-0509-5
- NAID
  40021443658
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-15K18975, KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K09208, KAKENHI-PROJECT-18K08138, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-15H05761
[Journal Article] Norepinephrine-induced adrenergic activation strikingly increased the atrial fibrillation duration through β1- and α1-adrenergic receptor-mediated signaling in mice.2015
- Author(s)
  Suita K, Fujita T, Hasegawa N, Cai W, Jin H, Hidaka Y, Prajapati R, Umemura M, Yokoyama U, Sato M, Okumura S, Ishikawa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 23;10(7) Issue: 7 Pages: e0133664-e0133664
- DOI
  10.1371/journal.pone.0133664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293236
[Journal Article] Coupling of beta1-adrenergic receptor to type 5 adenylyl cyclase and its physiological relevance in cardiac myocytes.2015
- Author(s)
  Tsunematsu T, Okumura S, Mototani Y, Ohnuki Y, Jin H, Cai W, SuitaK, Sato I, Umemura M, Yokoyama U, Sato M, Fujita T, and Ishikawa Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 458 Issue: 3 Pages: 531-535
- DOI
  10.1016/j.bbrc.2015.01.149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24790219, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293236
[Journal Article] Epac1 deficiency attenuated vascular smooth muscle cell migration and neointimal formation.2015
- Author(s)
  Kato Y, Yokoyama U, Yanai C, Ishige R, Kurotaki D, Umemura M, Fujita T, Kubota T, Okumura S, Sata M, Tamura T, Ishikawa Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 35(12) Issue: 12 Pages: 2617-2625
- DOI
  10.1161/atvbaha.115.306534
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-25293236
[Journal Article] Oscillation of cAMP and Ca(2+) in cardiac myocytes: a systems biology approach2015
- Author(s)
  Kamide T, Okumura S, Ghosh S, Shinoda Y, Mototani Y, Ohnuki Y, Jin H, Cai W, Suita K, Sato I, Umemura M, Fujita T, Yokoyama U, Sato M, Furutani K, Kitano H, Ishikawa Y
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 65(2) Issue: 2 Pages: 195-200
- DOI
  10.1007/s12576-014-0354-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136003, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24590319, KAKENHI-PROJECT-24790219, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506, KAKENHI-PLANNED-22136002, KAKENHI-PROJECT-25293236
[Journal Article] Role of Cyclic AMP Sensor Epac1 in Masseter Muscle Hypertrophy and Myosin Heavy Chain Transition Induced by 2-Adrenoceptor Stimulation.2014
- Author(s)
  Ohnuki Y, Umeki D, Mototani Y, Jin H, Cai W, Shiozawa K, Suita K, Saeki Y, Fujita T, Ishikawa Y, and Okumura S.
- Journal Title
  
  J. Physiol.
  
  Volume: 592 Issue: 24 Pages: 5461-5475
- DOI
  10.1113/jphysiol.2014.282996
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25670131
[Journal Article] Impaired NO Production and Increased Blood Pressure in Systemic Heterozygous ATP2B1 Null Mice.2014
- Author(s)
  Fujiwara A, Hirawa N, Fujita M, Kobayashi Y, Okuyama Y, Yatsu K, Katsumata M, Yamamoto y, Ichihara N, Saka S, Toya Y, Yasuda G, Tabara Y, Miki T, Ueshima H, Ishikawa Y, and Umemura S
- Journal Title
  
  J Hypertension.
  
  Volume: 32 Issue: 7 Pages: 1415-1423
- DOI
  10.1097/hjh.0000000000000206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390084, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293196, KAKENHI-PROJECT-25461249, KAKENHI-PROJECT-25670131
[Journal Article] Three-Dimensional Multilayers of Smooth Muscle Cells as a New Experimental Model for Vascular Elastic Fiber Formation Studies.2014
- Author(s)
  Ishiwata R, Yokoyama U, Matsusaki M, Yoshiya A, Kadowaki K, Ichikaww Y, Umemura M, Fujita T, Minamisawa S, Shimoda H, Mitsuru Akashi M, and Ishikawa Y.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 233 Issue: 2 Pages: 590-600
- DOI
  10.1016/j.atherosclerosis.2014.01.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PROJECT-14J01039, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24659100, KAKENHI-PUBLICLY-25116719, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670096, KAKENHI-PROJECT-26670506
[Journal Article] Store-operated Ca2 entry (SOCE) Regulates Melanoma Proliferation and Cell Migration.2014
- Author(s)
  Umemura M, Baljinnyam E, Feske S, De Lorenzo MS, Lai-Hua Xie LH, Feng X, 1, Itoh K, Makino A, Fujita T, Yokoyama U, Iw atsubo M, Chen S, Goydos JS, I shikawa Y, and Iwatsubo K
- Journal Title
  
  PLoS ONE.
  
  Volume: 9 Issue: 2 Pages: e89292-e89292
- DOI
  10.1371/journal.pone.0089292
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PUBLICLY-25116719, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506
[Journal Article] Protection of cardiomyocytes from the hypoxia-mediated injury by a peptide targeting the activator of G-protein signaling 8.2014
- Author(s)
  Sato M, Hiraoka M, Suzuki H, Sakima M, Mamun, AA, Yamane Y, Fujita T, Yokoyama U, Okumura S, and Ishikawa Y.
- Journal Title
  
  PLoS ONE.
  
  Volume: 9 Issue: 3 Pages: e91980-e91980
- DOI
  10.1371/journal.pone.0091980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-23591087, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24590280, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506
[Journal Article] Disruption of Epac1 decreasesphosphorylation of phospholamban and protects theheart against stresses.2014
- Author(s)
  Okumura S, Fujita T, Cai W, Jin M, Namekata I, Mototani Y, Jin HL, Ohnuki Y, Tsuneoka Y, Kurotani R, Suita Km Kawakami Y, Hamaguchi S, Abe T, Kiyonari H, Tsunematsu T, Bai Y, Suzuki S, Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko H, Adachi-Akahane S, Tanaka H, and Ishikawa Y.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390200
[Journal Article] Hyperthermia generated with ferucarbotran (Resovis®) in an alternating magnetic field enhances cisplatin-induced apoptosis of cultured human oral cancer cells.2014
- Author(s)
  Sato I, Umemura M, Mitsudo K, Kioi M, Nakashima H, Iwai T Fujita T, Yokoyama U, Okumura S, Feng X, Ito K, Miyajima A, Makino A, Iwai M, Eguchi H, I wai T, and Ishikawa Y.
- Journal Title
  
  J. Physiol. Sci.
  
  Volume: 64 Issue: 3 Pages: 177-183
- DOI
  10.1007/s12576-014-0309-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-23591087, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24590280, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-26870481
[Journal Article] Decreased serum osmolality promotes ductus arteriosus constriction.2014
- Author(s)
  Aoki R, Yokoyama U, Ichikawa Y, Taguri M, Kumagaya S, Ishiwata R, Yanai C, Fujita S, Umemura M, Fujita T, Okumura S, Sato M, Minamisawa S, Asou T, Masuda M, Iwasaki S, Nishimaki S, Seki K, Yokota S, Ishikawa Y.
- Journal Title
  
  Cardiovascular Research
  
  Volume: 104(2) Issue: 2 Pages: 326-36
- DOI
  10.1093/cvr/cvu199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J01039, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24590280, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26293249, KAKENHI-PROJECT-26462114, KAKENHI-PROJECT-26670506
[Journal Article] The prostanoid EP4 receptor and its signaling pathway.2013
- Author(s)
  Yokoyama U, Iwatsubo K, Umemura M, Fujita T, and Ishikawa Y.
- Journal Title
  
  Pharmacol Rev.
  
  Volume: 65 Issue: 3 Pages: 1010-1052
- DOI
  10.1124/pr.112.007195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24659100, KAKENHI-PUBLICLY-25116719, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131
[Journal Article] Pharmacological Stimulation of Type 5 Adenylyl Cyclase Stabilizes Heart Rate Under Both Microgravity and Hypergravity Induced by Parabolic Flight2012
- Author(s)
  Bai Y, et al.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 119 Issue: 4 Pages: 381-389
- DOI
  10.1254/jphs.12102FP
- NAID
  10031071685
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-22590811, KAKENHI-PROJECT-23591087, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24591151
[Journal Article] Mice Lacking Hypertension Candidate Gene ATP2B1 in Vascular Smooth Muscle Cells show Significant Blood Pressure Elevation.2012
- Author(s)
  Kobayashi Y, et al.
- Journal Title
  
  Hypertension.
  
  Volume: 59 Issue: 4 Pages: 854-860
- DOI
  10.1161/hypertensionaha.110.165068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-22659143, KAKENHI-PROJECT-23390188, KAKENHI-PROJECT-23791233, KAKENHI-PROJECT-24390084, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24790950
[Journal Article] Effect of ascorbic acid on reactive oxygen species production in chemotherapy and hyperthermia in prostate cancer cells.2012
- Author(s)
  Fukumura H, et al.
- Journal Title
  
  J. Physiol. Sci.
  
  Volume: 62 Issue: 3 Pages: 251-257
- DOI
  10.1007/s12576-012-0204-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PROJECT-21590936, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-23591087, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24659100, KAKENHI-PUBLICLY-23116514
[Journal Article] – The Role of the β-Adrenergic Receptor-Mediated Signaling Pathway and p53-Mediated Signaling Pathway in the Apoptosis of Cardiomyocytes –2011
- Author(s)
  Fujita T, Ishikawa Y
- Journal Title
  
  Circ J
  
  Volume: 75 Issue: 8 Pages: 1811-1818
- DOI
  10.1253/circj.CJ-11-0025
- NAID
  10029127431
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01418, KAKENHI-PROJECT-21390246, KAKENHI-PLANNED-22136009
[Patent] グルタミン酸による動脈管開存症の予防または治療2015
- Inventor(s)
  横山詩子、石川義弘、藤田秀次郎
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-02-07
- Overseas
- Data Source
  KAKENHI-PROJECT-24390200
[Patent] グルタミン酸による動脈管開存症の予防又は治療2015
- Inventor(s)
  横山詩子、石川義弘、藤田秀次郎
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-02-17
- Overseas
- Data Source
  KAKENHI-PLANNED-22136009
[Patent] グルタミン酸による動脈管開存症の予防又は治療2014
- Inventor(s)
  横山詩子、石川義弘、藤田秀二郎
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-050206
- Filing Date
  2014-03-13
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] The role of Epac1 in the development of ventricular arrhythmia in mice．2018
- Author(s)
  Prajapati R，Fujita T，Suita K，Nakamura T，Cai W，Hidaka Y，Okumura S，Ishikawa Y.
- Organizer
  第28回日本病態生理学会大会.
- Data Source
  KAKENHI-PROJECT-18KT0073
[Presentation] ビダラビンの不整脈治療における有用性2016
- Author(s)
  藤田孝之、吹田憲治、蔡　文倩、金　慧玲、日高　祐子、石川　義弘
- Organizer
  第93回日本生理学会大会合同大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] 未熟児動脈管開存症治療におけるアミノ酸輸液組成の重要性　The effect of amino acids on patent ductus arteriosus in preterm infants.The effect of amino acids on patent ductus arteriosus in preterm infants.　The effect of amino acids on patent ductus arteriosus in preterm infants.2015
- Author(s)
  横山詩子, 藤田秀次郎, 青木理加, 岩崎志穂, 麻生俊英, 益田宗孝, 関和男, 石川義弘
- Organizer
  第51回日本小児循環器学会総会・学術集会
- Place of Presentation
  ホテル日航東京（東京都港区）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Cardiac overexpression of Translationally Controlled Tumor Protein (TCTP) prevents the development of Dihydroartemisinin(DHA)-induced heart.2015
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, Hasegawa N, Ishikawa Y.
- Organizer
  The 79th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪・堂島リバーフォーラム・ＡＢＣホール（大阪府大阪市）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] 交感神経活性化による心房細動/心房粗動の延長におけるアドレナリン受容体の役割.2015
- Author(s)
  長谷川希望, 藤田孝之, 吹田憲治, 祭　文倩, 金　慧玲, 日高祐子, Rajesh Prajapati, 石川義弘
- Organizer
  第36回循環制御医学会総会
- Place of Presentation
  ウィンク愛知（愛知県名古屋市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] 抗ヘルペス薬による心房細動抑制．2014
- Author(s)
  吹田憲治, 藤田孝之, 奥村敏, 石川義弘
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市立大学医学部ﾍﾎﾞﾝﾎｰﾙ（神奈川県）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤ビダラビンによる心房細動抑制.2014
- Author(s)
  吹田憲治, 藤田孝之, 蔡文倩, 金慧玲, 奥村敏, 石川義弘
- Organizer
  第35回日本循環制御医学会総会
- Place of Presentation
  九州大学医学部百年講堂（福岡県）
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] EPAC1 plays an important role in regulation of renin and AQP2 expression in the kidney of mice.2014
- Author(s)
  Jin H, Fujita T, Cai W, Hidaka Y, Sagara S, Kubota K, Suita K, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress 2014
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-31
- Data Source
  KAKENHI-PROJECT-25460296
[Presentation] 抗ヘルペス薬による心房細動抑制．2014
- Author(s)
  吹田憲治, 藤田孝之, 奥村敏, 石川義弘
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市立大学医学部（神奈川県）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Cardiac overexpression of Translationally Controlled Tumor Protein (TCTP) prevents the development of doxorubicin-induced heart failure.2013
- Author(s)
  Fujita T, Cai W, Hidaka Y, Jin H, Jin M, Suita K, Ishikawa Y
- Organizer
  European Socirty of Cardiology.
- Place of Presentation
  Amsterdam ,Netherladns
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Aspartic acid promotes closure of the rat ductus arteriosus.2013
- Author(s)
  Fujita S, Yokoyama U, Nagao K, Jinzu H, Aoki R, Ichikawa Y, Iwasaki S, Nishimaki S, Seki K
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤ビダラビンによる不整脈治療の可能性.2013
- Author(s)
  吹田憲治, 藤田孝之, 石川義弘
- Organizer
  生理学研究所研究会, ―心血管膜輸送分子の構造・機能・病態の統合的研究戦略,
- Place of Presentation
  自然科学研究機構生理学研究所（愛知県）
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Inhibitor of cardiac adenylyl cyclase prevents atrial fibrillation in mice.2013
- Author(s)
  Suita K, Cai W, Jin H, Jin M, Fujita T, Okumura S, Ishikawa Y
- Organizer
  HD Physiology, the 2nd International Symposium
- Place of Presentation
  丸ノ内ＭＵＰＬＡＺＡ（東京都）
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Vidarabine, an anti-herpesvirus agent, prevents atrial fibrillation in mice.2013
- Author(s)
  Suita K, Cai W, Jin H, Jin M, Fujita T, Okumura S, Ishikawa Y
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] 出生後血清浸透圧変化からみた動脈管開存症発症リスク因子の検討.2013
- Author(s)
  青木理加, 横山詩子, 藤田秀次郎, 市川泰広, 岩崎志穂, 関　和男, 西巻　滋, 横田俊平, 石川義弘
- Organizer
  第49回日本周産期新生児学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Epac1 pathway plays an important role for the development of heart failure through the activation cAMP.2013
- Author(s)
  Cai W, Okumura S, Fujita T, Jin M, Suita K, Jin H, Hidaka Y, Ishikawa Y
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Pharmacological inhibition of STAT3 protect heart from lipopolysaccharide-induced cardiac dysfunction through the inhibition of Jak2/STAT3/iNOS signaling.2013
- Author(s)
  Jin H, Okumura S, Jin M, Cai W, Suita K, Bai Y, Tsunematsu T, Fujita T, Ishikawa Y
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan, Tokyo
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Disruption of Epacl decreases phosphorylation of phospholamban and protects the heart against stress.2012
- Author(s)
  Okumura S, Jin M, Ohnuki Y, Namekata I, Kurotani R, Fujita T, Jin HL, Cai W, Bai Y, Suita K, Tsunematsu T, Tanaka H, Ishikawa Y
- Organizer
  The 86^<th> American Heart Association ScientificSessions.
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] アミノ酸輸液の組成の違いが動脈管閉鎖に及ぼす作用の検討2012
- Author(s)
  藤田秀次郎, 横山詩子, 青木理加, 小郷寛史, 岩崎志穂, 西巻滋, 関和男, 石川義弘
- Organizer
  第48回日本周産期・新生児医学会学術集会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Disruption of Epac1 decreases phosphorylation of phospholamban and protects the heart against stress.2012
- Author(s)
  Okumura S, Jin M, Ohnuki Y, Namekata I, Kurotani R, Fujita T, Jin HL, Cai W, Bai Y, Suita K, Tsunematsu T, Tanaka H, Ishikawa Y
- Organizer
  The 86th American Heart Association Scientific Sessions
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] アミノ酸輸液の組成の違いが動脈管閉鎖に及ぼす作用の検討.2012
- Author(s)
  藤田秀次郎, 横山詩子, 青木理加, 小郷寛史, 岩崎志穂, 西巻滋, 関和男, 石川義弘
- Organizer
  第48回日本周産期・新生児医学会学術集会
- Place of Presentation
  大宮ソニックシティ（埼玉県）
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤ビダラビンによる心房細動抑制.
- Author(s)
  吹田憲治, 藤田孝之, 蔡文倩, 金慧玲, 奥村敏, 石川義弘
- Organizer
  第35回日本循環制御医学会総会
- Place of Presentation
  九州大学医学部百年講堂（福岡県）
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] 出生後血清浸透圧変化からみた動脈管開存症発症リスク因子の検討.
- Author(s)
  青木理加, 横山詩子, 藤田秀次郎, 市川泰広, 岩崎志穂, 関　和男, 西巻　滋, 横田俊平, 石川義弘.
- Organizer
  第49回日本周産期新生児学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2013-07-14 – 2013-07-16
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] EPAC1 plays an important role in regulation of renin and AQP2 expression in the kidney of mice.
- Author(s)
  Jin H, Fujita T, Cai W, Hidaka Y, Sagara S, Kubota K, Suita K, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Cardiac overexpression of Translationally Controlled Tumor Protein (TCTP) prevents the development of doxorubicin-induced heart failure.
- Author(s)
  Fujita T, Cai W, Hidaka Y, Jin H, Jin M, Suita K, Ishikawa Y
- Organizer
  European Socirty of Cardiology
- Place of Presentation
  Amsterdam,Netherland
- Year and Date
  2013-08-31 – 2013-09-04
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] 体液量調節におけるEPAC1の役割についての検討.
- Author(s)
  Jin H, Fujita T, Cai W, Hidaka Y, Sagara S, Suita K, Ishikawa Y
- Organizer
  第５７会日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] 体液量調節におけるEPAC1の役割についての検討.
- Author(s)
  Jin H, Fujita T, Cai W, Hidaka Y, Sagara S, Suita K, Ishikawa Y
- Organizer
  第５７会日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤ビダラビンによる不整脈治療の可能性.
- Author(s)
  吹田憲治, 藤田孝之, 石川義弘
- Organizer
  生理学研究所研究会, ―心血管膜輸送分子の構造・機能・病態の統合的研究戦略.
- Place of Presentation
  自然科学研究機構生理学研究所（愛知県）
- Year and Date
  2013-11-27 – 2013-11-28
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] EPAC1 plays an important role in regulation of renin and AQP2 expression in the kidney of mice.
- Author(s)
  Jin H, Fujita T, Cai W, Hidaka Y, Sagara S, Kubota K, Suita K, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Doxorubicin-induced Down-regulation Translationally Controlled Tumor Protein (TCTP) is an Important Mechanism in the Development of Heart Failure.
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, Ishikawa Y
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム、ＪＰタワーホール＆カンファレンス、東京商工会議所（東京都）
- Year and Date
  2014-03-21 – 2014-03-23
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced atrial fibrillation in mice.
- Author(s)
  Sujita K, Fujita T, Cai W, Hidaka Y, Jin H, Jin M, Okumura S, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Vidarabine, an anti-herpesvirus agent, attenuates Ca2+ leak from sarcoplasmic reticulum in cardiomyocytes and prevents atrial fibrillation in mice.
- Author(s)
  Suita K, Cai W, Jin H, Jin M, Fujita T, Okumura S, Ishikawa Y
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム、ＪＰタワーホール＆カンファレンス、東京商工会議所（東京都）
- Year and Date
  2014-03-21 – 2014-03-23
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Cardiac overexpression ofure. Chronic Treatment with Dihydroartemisinin, a TCTP　Down-regulating Agent, Results in Cardiac Dysfunction in Mice．
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, K. Sagara S, Kubota K, Suita K, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced atrial fibrillation in mice.
- Author(s)
  Suita K, Fujita T, Cai W, Hidaka Y, Jin H, Jin M, Okumura S, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Inhibitor of cardiac adenylyl cyclase prevents atrial fibrillation in mice.
- Author(s)
  Suita K, Cai W, Jin H, Jin M, Fujita T, Okumura S, Ishikawa Y
- Organizer
  HD Physiology, the 2nd International Symposium.
- Place of Presentation
  丸ノ内MYPLAZA(東京都）
- Year and Date
  2013-06-28 – 2014-06-29
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Cardiac overexpression of Translationally Controlled Tumor Protein (TCTP) prevents the development of Dihydroartemisinin (DHA)-induced heart.
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, Hasegawa N, Ishikawa Y.
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場、リーガロイヤルホテル大阪、堂島リバーフォーラム、ＡＢＣホール(大阪府）
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PLANNED-22136009
[Presentation] Cardiac overexpression ofure. Chronic Treatment with Dihydroartemisinin, a TCTP　Down-regulating Agent, Results in Cardiac Dysfunction in Mice．
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, K. Sagara S, Kubota K, Suita K, Ishikawa Y.
- Organizer
  European Society of Cardiorogy Congress.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-24390200
[Presentation] Cardiac overexpression of Translationally Controlled Tumor Protein (TCTP) prevents the development of Dihydroartemisinin (DHA)-induced heart.
- Author(s)
  Cai W, Fujita T, Hidaka Y, Jin H, Hasegawa N, Ishikawa Y.
- Organizer
  第79回日本循環器学会学術集会.
- Place of Presentation
  大阪国際会議場、リーガロイヤルホテル、堂島リバーフォーラム、ＡＢＣホール（大阪府）
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-24390200
[]

1. ISHIKAWA YOSHIHIRO (40305470)

# of Collaborated Projects: 3 results

# of Collaborated Products: 51 results
2. UMEMURA Masanari (50595353)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. CHIBA Yumi (10313256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 横山詩子 (70404994)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. 石上友章 (50264651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. AKAHANE Satomi (00184185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SATO Motohiko (40292122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. OKUMURA Satoshi (60233475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
9. 市川泰弘 (10555121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 齋藤純一 (30779301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 峯岸慎太郎 (80458398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宮川繁 (70544237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐々木紀彦 (80639063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 川上恭司郎 (90589227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KUROTANI Reiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 宮崎龍彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 伊藤智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 北野宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 市川泰広

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 加藤優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujita Takayuki 藤田 孝之

FUJITA Takayuki 藤田 孝之

Research Projects

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Co-Researchers

交感神経の有害シグナルの選択的抑制による、より安全で有効な心疾患治療戦略の開発Principal Investigator

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Effects of nutrition, aging, and stem cell against inflammation on high-risk heart disease, and evaluation of tissue regeneration ability.

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The usefulness of an AC5 inhibitor metabolite in the treatment of arrhythmias.Principal Investigator

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How to predict the collapse of homeostasis in circulatory regulation

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Evaluation of effects on age and tissue regeneration by exercise intervention on high-risk myocardial infarction

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The role of Epac in the development of arteriosclerosisPrincipal Investigator

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The role of EPAC in development of hypertensionPrincipal Investigator

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Molecular regulation of cardiac function by the automatic nervous system

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Integration of the regulation of cardiac myocyte signal pathway and neuro hormonal regulation

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Fortilin, a novel p53 inhibiting protein, in cardiovascular system.Principal Investigator

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[Journal Article] The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis.2023

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[Journal Article] Diagnostic potential of serum extracellular vesicles expressing prostate-specific membrane antigen in urologic malignancies.2021

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[Journal Article] Excessive EP4 signaling in smooth muscle cells induces abdominal aortic aneurysm by amplifying inflammation2020

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Fujita Takayuki 藤田孝之

FUJITA Takayuki 藤田孝之