OHMURA Mitsuyo 大村光代

Researcher Number	40468509
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2012: 慶應義塾大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Tumor biology
Keywords	Principal Investigator 代謝変動 / 細胞周期 / がん肝転移 / 質量顕微鏡 / 質量分析イメージング技術 / 細胞周期(Fucci)

Research Projects
(1 results)
Research Products
(16 results)

Metabolomic profile of cell cycle dependent human derived colon cancer cells using Microscopic imaging mass spectrometryPrincipal Investigator
- Principal Investigator
  
  OHMURA Mitsuyo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Tumor biology
- Research Institution
  Keio University

All 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 「代謝システム生物学の新たな理解に向けて」、実験医学別冊「質量分析実験ガイド」2013
- Author(s)
  末松誠、大村光代、森川隆之、笠原正貴、久保亜紀子、南嶋洋司、梶村眞弓
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23800054
[Book] がん代謝システムの顕微質量イメージングによる解析2012
- Author(s)
  末松誠、久保亜紀子、大村光代、菱木貴子、梶村眞弓、加部泰明、杉浦悠毅
- Data Source
  KAKENHI-PROJECT-23800054
[Book] ガス分子を介した代謝システム制御機構:酸素とグルコースが紡ぐ複雑系2011
- Author(s)
  末松誠、菱木貴子、久保亜紀子、大村光代、梶村眞弓、加部泰明、高野直治、山本雄広
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells2012
- Author(s)
  Tamada M., Nagano O., Tateyama S., Ohmura M., Yae T., Ishimoto T., Sugihara E., Onishi N., Yamamoto T., Yanagawa H.Suematsu M., and Saya H
- Journal Title
  
  Cancer Res
  
  Volume: 72 Pages: 1438-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] Alternative splicing of CD44mRNA by ESRP1 enhances lung colonization of metastatic cancer cell2012
- Author(s)
  Yae T., Tsuchihashi K., Ishimoto T., Motohara T., Yoshikawa M., Yoshida G., Wada T., Masuko T., Moguchi K., Tanaka H., Osawa T., Kanki Y., Minami T., Aburatani H., Ohmura M., Kubo A., Suematsu M., Takahashi K., Saya H., and Nagano O
- Journal Title
  
  Nature Comm
  
  Volume: 3 Pages: 883-883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] 質量分析によるがんの分子イメージング2011
- Author(s)
  涌井昌俊、久保亜紀子、大村光代、末松誠
- Journal Title
  
  最新医学
  
  Volume: 66 Pages: 2321-2329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] Semi-quantitative analyses of metabolic systems of human colon cancer metastatic xenografts in livers of superimmunodeficient NOG mice2011
- Author(s)
  Kubo A., Ohmura M., Wakui M., Harada T., Kajihara S., Ogawa K., Suemizu H., Nakamura M., Setou M., and Suematsu M
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 400 Pages: 1895-1904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth2011
- Author(s)
  Ishimoto T., Nagano O., Yae T., Tamada M., Motohara T., Oshima H., Oshima M., Ikeda T., Asaba R., Yagi H., Ishikawa T., Kai K., Takahashi E., Imamura Y., Baba Y., Ohmura M., Suematsu M., Baba H. and Saya H
- Journal Title
  
  Cancer Cell
  
  Volume: 19 Pages: 387-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] Microscopic imaging mass spectrometry assisted by on tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts
- Author(s)
  Toue S., Sugiura Y., Kubo A., Ohmura M., Karakawa S., Mizukoshi T., Yoneda J., Miyano H., Noguchi Y., Kobayashi T., Kabe Y., Suematsu M.
- Journal Title
  
  Proteomics
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Journal Article] Energy management by enhanced glycolysis in G1 phase in human colon cancer cells in vivo and in vitro
- Author(s)
  Bao Y., Mukai K., Hishiki T., Kubo A., Ohmura M., Sugiura Y., Matsuura T., Nagahata Y., Yamamoto T., Fukuda R., Saya H., Suematsu M., and Minamishima Y
- Journal Title
  
  Molecular Cancer Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23800054
[Presentation] 誘導体化イメージング質量分析による,複数種アミノ酸の局在イメージング法の開発2012
- Author(s)
  東江咲乃、杉浦悠毅、久保亜紀子、大村光代、加部泰明、末松誠
- Organizer
  第85回日本生化学学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23800054
[Presentation] in situmetabolic flow analyses of 13C3alanine in tumor bearing-liver using CE-MS and MALDI mass spectrometric imaging2012
- Author(s)
  Kubo A., Ohmura M., Hishiki T., Wakui M., Suematsu M
- Organizer
  第60回ASMS
- Place of Presentation
  USA
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23800054
[Presentation] 高分解能質量顕微鏡を用いた肝転移がんの代謝プロファイルの解明2012
- Author(s)
  大村光代、久保亜紀子、東江咲乃、杉浦悠毅、中西豪、加部泰明、末松誠
- Organizer
  第85回日本生化学学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23800054
[Presentation] Microscopic MALDI imaging revealed heterogenous distribution of metastasis in and around hepatic metastasis of human colon cancer xenograft in mice2011
- Author(s)
  Kubo A., Ohmura M., Hishiki T., Wakui M.,Murata M., Setoh M., Suematsu M.
- Organizer
  第59回ASMS
- Place of Presentation
  USA
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-23800054
[Presentation] 高分解能質量顕微鏡によるがん転移肝の代謝変動の解明2011
- Author(s)
  大村光代、久保亜紀子、涌井昌俊、末水洋志、中村雅登、小河潔、瀬籐光利、末松誠
- Organizer
  第84回日本生化学学会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23800054
[Presentation] 質量顕微鏡とCE-MSを用いたヒト大腸がん肝転移モデルの半定量的局所代謝解析2011
- Author(s)
  久保亜紀子、大村光代、涌井昌俊、小河潔、瀬籐光利、末松誠
- Organizer
  第84回日本生化学学会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23800054

OHMURA Mitsuyo 大村 光代

Research Projects

Research Products

Metabolomic profile of cell cycle dependent human derived colon cancer cells using Microscopic imaging mass spectrometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「代謝システム生物学の新たな理解に向けて」、実験医学別冊「質量分析実験ガイド」2013

Author(s)

Publisher

Data Source

[Book] がん代謝システムの顕微質量イメージングによる解析2012

Author(s)

Data Source

[Book] ガス分子を介した代謝システム制御機構:酸素とグルコースが紡ぐ複雑系2011

Author(s)

Data Source

[Journal Article] Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells2012

Author(s)

Journal Title

Data Source

[Journal Article] Alternative splicing of CD44mRNA by ESRP1 enhances lung colonization of metastatic cancer cell2012

Author(s)

Journal Title

Data Source

[Journal Article] 質量分析によるがんの分子イメージング2011

Author(s)

Journal Title

Data Source

[Journal Article] Semi-quantitative analyses of metabolic systems of human colon cancer metastatic xenografts in livers of superimmunodeficient NOG mice2011

Author(s)

Journal Title

Data Source

[Journal Article] CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth2011

Author(s)

Journal Title

Data Source

[Journal Article] Microscopic imaging mass spectrometry assisted by on tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts

Author(s)

Journal Title

Data Source

[Journal Article] Energy management by enhanced glycolysis in G1 phase in human colon cancer cells in vivo and in vitro

Author(s)

Journal Title

Data Source

[Presentation] 誘導体化イメージング質量分析による,複数種アミノ酸の局在イメージング法の開発2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] in situmetabolic flow analyses of 13C3alanine in tumor bearing-liver using CE-MS and MALDI mass spectrometric imaging2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 高分解能質量顕微鏡を用いた肝転移がんの代謝プロファイルの解明2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Microscopic MALDI imaging revealed heterogenous distribution of metastasis in and around hepatic metastasis of human colon cancer xenograft in mice2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 高分解能質量顕微鏡によるがん転移肝の代謝変動の解明2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 質量顕微鏡とCE-MSを用いたヒト大腸がん肝転移モデルの半定量的局所代謝解析2011

Author(s)

Organizer

OHMURA Mitsuyo 大村光代