Tsukumo Yoshinori 築茂由則

… Alternative Names

Researcher Number	40469630
Other IDs
Affiliation (Current)	2020: 国立医薬品食品衛生研究所, 遺伝子医薬部, 主任研究官 2020: 公益財団法人がん研究会, がん化学療法センターゲノム研究部, 研究員
Affiliation (based on the past Project Information) *help	2019: 国立医薬品食品衛生研究所, 遺伝子医薬部, 主任研究官 2016 – 2017: 国立医薬品食品衛生研究所, 遺伝子医薬部, 主任研究官 2011: 公益財団法人がん研究会, がん化学療法センターゲノム研究部, 研究員 2011: 公益財団法人がん研究会, がん化学療法センター・ゲノム研究部, 研究員 2010: (財)癌研究会, 癌化学療法センターゲノム研究部, 研究員
Review Section/Research Field	Principal Investigator Tumor biology / Tumor diagnostics / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 翻訳 / 肺がん / バイオマーカー / EGFR / ストレス応答タンパク / 小胞体 / mRNA / リボソーム / 翻訳開始因子 / 腫瘍 … More

EGFR肺がん特異的翻訳産物の機能解析と新規治療法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  築茂由則
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institute of Health Sciences
Screening of biomarkers to predict the drug efficacy based on translation profilingPrincipal Investigator
- Principal Investigator
  
  Tsukumo Yoshinori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  National Institute of Health Sciences
Studies on selective translation mechanism of stress response Protein under global translational repressionPrincipal Investigator
- Principal Investigator
  
  TSUKUMO Yosinori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research

All 2017 2016 2012 2011

All Journal Article Presentation

[Journal Article] Current and Future Issues of Companion Diagnostics2017
- Author(s)
  築茂由則, 鈴木孝昌, 内藤幹彦
- Journal Title
  
  RSMP
  
  Volume: 7 Issue: 2 Pages: 71-80
- DOI
  10.14982/rsmp.7.71
- NAID
  130007040567
- ISSN
  2185-7113, 2189-0447
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18444
[Journal Article] Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3.2016
- Author(s)
  Tsukumo Y, Alain T, Fonseca BD, Nadon R, Sonenberg N.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Pages: 11776-11776
- DOI
  10.1038/ncomms11776
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18444
[Journal Article] Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.2016
- Author(s)
  Tahmasebi S, Jafarnejad SM, Tam IS, Gonatopoulos-Pournatzis T, Matta-Camacho E, Tsukumo Y, Yanagiya A, Li W, Atlasi Y, Caron M, Braunschweig U, Pearl D, Khoutorsky A, Gkogkas CG, Nadon R, Bourque G, Yang XJ, Tian B, Stunnenberg HG, Yamanaka Y, Blencowe BJ, Giguere V, Sonenberg N.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 113 Pages: 12360-12367
- DOI
  10.1073/pnas.1615540113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18444
[Journal Article] Transcriptional induction of 4E-BP3 prolongs translation repression.2016
- Author(s)
  Tsukumo Y, Sonenberg N, Alain T.
- Journal Title
  
  Cell Cycle
  
  Volume: 15 Pages: 3325-3326
- DOI
  10.1080/15384101.2016.1224786
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18444
[Journal Article] Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation2012
- Author(s)
  Junichi Matsuo, Yoshinori Tsukumo (co-first), et al
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 11 Pages: 1082-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700892
[Journal Article] Hyperactivation of 4E-binding protein 1 as a mediator of iguanide-induced cytotoxicity during glucose deprivation.2012
- Author(s)
  Matsuo J, Tsukumo Y, Saito S, Tsukahara S, Sakurai J, Sato S, Kondo H, Ushijima M, Matsuura M, Watanabe T, Tomida A
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 11(5) Pages: 1082-1091
- DOI
  10.1158/1535-7163.mct-11-0871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300109, KAKENHI-PROJECT-22300342, KAKENHI-PROJECT-22700892, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626
[Presentation] Establishment of EGFR L858R-knock-in cells using a genome editing technology and their EGFR-TKI sensitivity2017
- Author(s)
  築茂由則, 鈴木孝昌, 内藤幹彦
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K18444
[Presentation] ビグアナイド系化合物による4E-BP1の活性化と抗腫瘍効果2011
- Author(s)
  築茂由則、近藤裕道、冨田章弘
- Organizer
  分指標的治療学会
- Place of Presentation
  東京
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22700892
[Presentation] Hyper-activation of 4E-binding protein 1 by anti-diabetic biguanide as its anti-tumor mechanisms of action2011
- Author(s)
  Yoshinori Tsukumo, Junichi Matsuo, Satomi Tsukahara, Junko Sakurai, Toshiki Watanabe, Sigeo Sato, Hiromichi Kondo, and Akihiro Tomida
- Organizer
  American Association for Cancer Research, Special conference
- Place of Presentation
  サンフランシスコ
- Year and Date
  2011-02-26
- Data Source
  KAKENHI-PROJECT-22700892
[Presentation] ビグアナイド系化合物による4E-BP1の活性化と抗腫瘍効果2011
- Author(s)
  築茂由則
- Organizer
  分子標的治療学会
- Place of Presentation
  東京ホテル日航東京
- Data Source
  KAKENHI-PROJECT-22700892
[Presentation] Hyper-activation of 4E-binding protein 1 by anti-diabetic biguanide as its anti-tumor mechanisms of action2011
- Author(s)
  築茂由則
- Organizer
  American Association for Cancer Research, Special conference, "Targeting PI3K/mTOR signaling in cancer"
- Place of Presentation
  サンフランシスコ
- Year and Date
  2011-02-26
- Data Source
  KAKENHI-PROJECT-22700892

1. HARA Toshihide

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. ITO Youichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 松浦正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 牛嶋大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 冨田章弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsukumo Yoshinori 築茂 由則

築茂 由則 ツクモ ヨシノリ

TSUKUMO Yosinori 築茂 由則

Research Projects

Research Products

Co-Researchers

EGFR肺がん特異的翻訳産物の機能解析と新規治療法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Screening of biomarkers to predict the drug efficacy based on translation profilingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on selective translation mechanism of stress response Protein under global translational repressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Current and Future Issues of Companion Diagnostics2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptional induction of 4E-BP3 prolongs translation repression.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation2012

Author(s)

Journal Title

Data Source

[Journal Article] Hyperactivation of 4E-binding protein 1 as a mediator of iguanide-induced cytotoxicity during glucose deprivation.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Establishment of EGFR L858R-knock-in cells using a genome editing technology and their EGFR-TKI sensitivity2017

Author(s)

Organizer

Data Source

[Presentation] ビグアナイド系化合物による4E-BP1の活性化と抗腫瘍効果2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hyper-activation of 4E-binding protein 1 by anti-diabetic biguanide as its anti-tumor mechanisms of action2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ビグアナイド系化合物による4E-BP1の活性化と抗腫瘍効果2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Hyper-activation of 4E-binding protein 1 by anti-diabetic biguanide as its anti-tumor mechanisms of action2011

Author(s)

Organizer

Tsukumo Yoshinori 築茂由則

築茂由則ツクモヨシノリ

TSUKUMO Yosinori 築茂由則