NISHIMURA MITSUHIRO 西村光広

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Nishimura Mitsuhiro 西村光広

NISHIMURA Mitsuhiro 西村光広

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Researcher Number	40510285
Other IDs	https://orcid.org/0000-0001-9541-3614
Affiliation (Current)	2025: 神戸大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 神戸大学, 医学研究科, 助教 2017 – 2023: 神戸大学, 医学研究科, 助教 2010: 大阪薬科大学, 薬学部, 博士研究員 2009: 大阪薬科大学, 薬学部, ポスト・ドクター
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Structural biochemistry Except Principal Investigator Physical pharmacy
Keywords	Principal Investigator X線結晶構造解析 / ヒトヘルペスウイルス6 / 構造生物学 / 中和抗体 / 立体構造解析 / 抗体 / ウイルスリガンド / 相互作用解析 / 電子顕微鏡解析 / ヘルペスウイルス6 … More / クライオ電子顕微鏡解析 / 転写活性化因子 / X線構造解析 / 蛋白質 / ウイルス / Ｘ線結晶解析 … More Except Principal Investigator レセプター / リガンド / 糖尿病血管合併症 / 合理的創薬 / 超遠心分析 / 超遠心分析用蛍光測定装置 / 分子間相互作用 / 糖尿病合併症 / 終末糖化産物 / 水和 / 等温滴定型熱量計 / PPARγ / AGE-RAGE相互作用 / AGE受容体 / 合理的薬物設計 / NMR / バーチャルスクリーニング / SBDD / RAGE / AGE / 最終糖化産物 / 糖尿病 / 創薬 Less

ヒトヘルペスウイルス6糖タンパク質複合体の動的立体構造の解明Principal Investigator
- Principal Investigator
  
  西村光広
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kobe University
ヒトヘルペスウイルス6感染に必須なウイルスリガンドの立体構造決定と機能解析Principal Investigator
- Principal Investigator
  
  西村光広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kobe University
Structure analysis of human herpesvirus 6 glycoprotein complex which is essential for the receptor bindingPrincipal Investigator
- Principal Investigator
  
  Nishimura Mitsuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kobe University
Structure based analysis of human herpesvirus 6 transactivator IE2Principal Investigator
- Principal Investigator
  
  Nishimura Mitsuhiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kobe University
Research and development of drugs of prevention and treatment for complication of diabetes targeting the receptor of advanced glycation end products(RAGE)
- Principal Investigator
  
  KOBAYASHI Yuji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2022 2020 2019 2017 2010 2008

All Journal Article Presentation

[Journal Article] Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD1342020
- Author(s)
  Mitsuhiro Nishimura, Dian Novita Krisdianto, Takayuki Kato, Lidya Handayani Tjan, Bochao Wang, Aika Wakata, Anna Lystia Poetranto, Akiko Kawabata, Huamin Tang, Taiki Aoshi, Yasuko Mori
- Journal Title
  
  PLoS Pathogens
  
  Volume: in press
- NAID
  120006878582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06512
[Journal Article] Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 22017
- Author(s)
  Nishimura Mitsuhiro、Wang Junjie、Wakata Aika、Sakamoto Kento、Mori Yasuko
- Journal Title
  
  Journal of Virology
  
  Volume: 91 Issue: 21
- DOI
  10.1128/jvi.01121-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15075
[Journal Article] Purification, Crystallization and X-ray Diffraction Study of the Cterminal Domain of Human Herpesvirus 6A Immediate Early Protein 22017
- Author(s)
  WANG JUNJIE, NISHIMURA MITSUHIRO, WAKATA AIKA、MORI YASUKO
- Journal Title
  
  Kobe Journal Medical Sciences
  
  Volume: 62
- NAID
  120006220839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15075
[Journal Article] Crystal Structure of Human Ribosomal Protein L10 Core Domain Reveals Eukaryote-Specific Motifs in Addition to the Conserved Fold2008
- Author(s)
  Nishimura M, Kaminishi T, Takemoto C, Kawazoe M, Yoshida T, Tanaka A, Sugano S, Shirouzu M, Ohkubo T, Yokoyama S, Kobayashi Y
- Journal Title
  
  J Mol Biol
  
  Volume: 377 Pages: 421-430
- URL
  http://www.sciencedirect.com/science/article/pii/S002228360800020X
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390013
[Presentation] ヒトヘルペスウイルス6B gH/gL/gQ1/gQ2複合体のX線結晶構造解析2022
- Author(s)
  西村光広、竹下浩平、有井　潤、森　康子
- Organizer
  第35回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-22K06113
[Presentation] Structure based analysis of human herpesvirus 6B glycoprotein complex with neutralizing antibodies2019
- Author(s)
  Mitsuhiro Nishimura, Dian Novita Krisdianto, Zhenxiao Ren, Bochao Wang, Aika Wakata, Anna Lystia Poetranto, Lidya Handayani Tjan, Takayuki Kato, Taiki Aoshi, Keiichi Namba, Yasuko Mori
- Organizer
  第 58回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06512
[Presentation] Molecular interaction of HHV-6B gH/gL/gQ1/gQ2 complex with the cellular receptor and neutralizing antibodies.2019
- Author(s)
  Mitsuhiro Nishimura, Dian Novita Krisdianto, Bochao Wang, Aika Wakata, Anna Lystia Poetranto, Lidya Handayani Tjan, Takayuki Kato, Taiki Aoshi, Keiichi Namba, Yasuko Mori
- Organizer
  11th International Conference on HHV-6 & 7
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06512
[Presentation] Structure of Human Herpesvirus 6A Immediate Early Protein 2 C-terminal Domain Revealed a Similarity with DNA Binding Proteins of Gammaherpesvirus2017
- Author(s)
  Mitsuhiro Nishimura, Wang Junjie, Aika Wakata, Kento Sakamoto, Yasuko Mori
- Organizer
  42nd Annual international herpesvirus workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15075
[Presentation] Structure-based analysis of human herpesvirus 6A immediate early protein 22017
- Author(s)
  Mitsuhiro Nishimura, Aika Wakata, Kento Sakamoto, Wang Junjie, Yasuko Mori
- Organizer
  10th International Conference on HHV-6 & 7
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15075
[Presentation] ヒトヘルペスウイルス6A 転写活性化因子IE2 C末端領域の立体構造解析2017
- Author(s)
  西村光広、若田愛加、王俊杰、森康子
- Organizer
  第31回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-17K15075
[Presentation] Structural analysis of human herpesvirus 6A immediate early protein 2 C-terminal Domain2017
- Author(s)
  Mitsuhiro Nishimura, Aika Wakata, Junjie Wang, Yasuko Mori
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15075
[Presentation] 毒素原性大腸菌の線毛形成蛋白質CofAの結晶化2010
- Author(s)
  小林祐次、西村光広, 他
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-21390013
[Presentation] PPARγ-リガンド複合体の結晶構造解析及び熱力学的相互作用解析2010
- Author(s)
  西村光広、小林祐次, 他
- Organizer
  Biophysical Interaction Analysis symposium 2010
- Place of Presentation
  東京
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21390013
[Presentation] Thermodynamic and structural analysis of PPARγ-ligand interaction2010
- Author(s)
  M.Nishimura, Y Kobayashi
- Organizer
  5th International Peptide Symposium in conjyunction with 47th Japanese Peptide Symposium
- Place of Presentation
  京都
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-21390013
[Presentation] PPARγ-リガンド複合体の分子間相互作用解析2010
- Author(s)
  西村光広、小林祐次, 他
- Organizer
  熱測定学会
- Place of Presentation
  三重
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21390013

1. KOBAYASHI Yuji (20127228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. YAMADA Takashi (20278592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NISHIMURA MITSUHIRO 西村 光広

Nishimura Mitsuhiro 西村 光広

NISHIMURA Mitsuhiro 西村 光広

Research Projects

Research Products

Co-Researchers

ヒトヘルペスウイルス6糖タンパク質複合体の動的立体構造の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒトヘルペスウイルス6感染に必須なウイルスリガンドの立体構造決定と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structure analysis of human herpesvirus 6 glycoprotein complex which is essential for the receptor bindingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structure based analysis of human herpesvirus 6 transactivator IE2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research and development of drugs of prevention and treatment for complication of diabetes targeting the receptor of advanced glycation end products(RAGE)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD1342020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 22017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Purification, Crystallization and X-ray Diffraction Study of the Cterminal Domain of Human Herpesvirus 6A Immediate Early Protein 22017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Crystal Structure of Human Ribosomal Protein L10 Core Domain Reveals Eukaryote-Specific Motifs in Addition to the Conserved Fold2008

Author(s)

Journal Title

URL

Data Source

[Presentation] ヒトヘルペスウイルス6B gH/gL/gQ1/gQ2複合体のX線結晶構造解析2022

Author(s)

Organizer

Data Source

[Presentation] Structure based analysis of human herpesvirus 6B glycoprotein complex with neutralizing antibodies2019

Author(s)

Organizer

Data Source

[Presentation] Molecular interaction of HHV-6B gH/gL/gQ1/gQ2 complex with the cellular receptor and neutralizing antibodies.2019

Author(s)

Organizer

Data Source

[Presentation] Structure of Human Herpesvirus 6A Immediate Early Protein 2 C-terminal Domain Revealed a Similarity with DNA Binding Proteins of Gammaherpesvirus2017

Author(s)

Organizer

Data Source

[Presentation] Structure-based analysis of human herpesvirus 6A immediate early protein 22017

Author(s)

Organizer

Data Source

[Presentation] ヒトヘルペスウイルス6A 転写活性化因子IE2 C末端領域の立体構造解析2017

Author(s)

Organizer

Data Source

NISHIMURA MITSUHIRO 西村光広

Nishimura Mitsuhiro 西村光広

NISHIMURA Mitsuhiro 西村光広