Shimojo Hiromi 下條博美

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HIROMI Shimojo 下條博美

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Researcher Number	40512306
Other IDs	https://orcid.org/0000-0001-5455-4218
Affiliation (Current)	2025: 大阪大学, 大学院生命機能研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院生命機能研究科, 助教 2019 – 2021: 大阪大学, 生命機能研究科, 助教 2018: 京都大学, ウイルス・再生医科学研究所, 特定助教 2014: 京都大学, 物質ー細胞統合システム拠点, 特定拠点助教 2013: 京都大学, 物質-細胞統合システム拠点, 特定拠点助教 2012: 京都大学, ウイルス研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Nerve anatomy/Neuropathology / Biological Sciences
Keywords	Principal Investigator 細胞分化 / ライブイメージング / 遺伝子発現動態 / 神経幹細胞 / 神経発生 / 遺伝子発現ダイナミクス / エピジェネティクス / 着床前胚 / 幹細胞 / 分子タイマー … More / 細胞運命決定 / Neurogenin / 神経分化 / Notchシグナル / 光遺伝学 / プロニューラル遺伝子 / シグナル伝達ダイナミクス / シグナル伝達 / 組織構築 / 細胞間相互作用 Less

エピブラスト運命決定過程における多能性因子Nanogの時期特異的な機能の解析Principal Investigator
- Principal Investigator
  
  下條博美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osaka University
Molecular clock regulating the timing of cell fate determinationPrincipal Investigator
- Principal Investigator
  
  Shimojo Hiromi
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osaka University
  Kyoto University
細胞集団制御における隣接細胞間シグナル伝達速度の意義Principal Investigator
- Principal Investigator
  
  下條博美
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Dynamic gene expression during mammalian neurogenesis.Principal Investigator
- Principal Investigator
  
  HIROMI Shimojo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells2024
- Author(s)
  Shimojo H, Masaki T, Kageyama R.
- Journal Title
  
  Dev. Cell
  
  Volume: 59 Issue: 15 Pages: 1-11
- DOI
  10.1016/j.devcel.2024.04.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06254
[Journal Article] Dynamic transcriptional control of neural stem cells2023
- Author(s)
  Kageyama R., Shimojo H.
- Journal Title
  
  Neocortical Neurogenesis in Development and Evolution
  
  Volume: ch6 Pages: 107-118
- DOI
  10.1002/9781119860914.ch6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06254
[Journal Article] Daughter cells inherit YAP localization from mother cells in early preimplantation embryos.2023
- Author(s)
  Otsuka T., Shimojo H., Sasaki H.
- Journal Title
  
  Dev. Growth Differ.
  
  Volume: 65(6) Issue: 6 Pages: 360-369
- DOI
  10.1111/dgd.12870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05782
[Journal Article] Biological Significance of the Coupling Delay in Synchronized Oscillations2023
- Author(s)
  Kageyama Ryoichiro、Isomura Akihiro、Shimojo Hiromi
- Journal Title
  
  Physiology
  
  Volume: 38 Issue: 2 Pages: 63-72
- DOI
  10.1152/physiol.00023.2022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04976, KAKENHI-PROJECT-18K06254, KAKENHI-PROJECT-21H03540
[Journal Article] Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells2021
- Author(s)
  Zhang Yao、Lahmann Ines、Baum Katharina、Shimojo Hiromi、Mourikis Philippos、Wolf Jana、Kageyama Ryoichiro、Birchmeier Carmen
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1318-1318
- DOI
  10.1038/s41467-021-21631-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06480, KAKENHI-PROJECT-18K06254
[Journal Article] Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain2020
- Author(s)
  Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R.
- Journal Title
  
  Development
  
  Volume: 147 Pages: 182204-182204
- DOI
  10.1242/dev.182204
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06254, KAKENHI-PLANNED-16H06480, KAKENHI-PROJECT-17J08651
[Journal Article] Real-time Bioluminescence Imaging of Notch Signaling Dynamics during Murine Neurogenesis.2019
- Author(s)
  Shimojo H and Kageyama R.
- Journal Title
  
  J. Vis. Exp.
  
  Volume: 12 Issue: 154
- DOI
  10.3791/60455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06254
[Journal Article] Dynamic control of neural stem cells by bHLH factors2019
- Author(s)
  Kageyama Ryoichiro、Shimojo Hiromi、Ohtsuka Toshiyuki
- Journal Title
  
  Neuroscience Research
  
  Volume: 138 Pages: 12-18
- DOI
  10.1016/j.neures.2018.09.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06253, KAKENHI-PROJECT-18K06254
[Journal Article] Oscillatory control of Notch signaling in development2018
- Author(s)
  Kageyama R, Shimojo H, Isomura A.
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1066 Pages: 265-277
- DOI
  10.1007/978-3-319-89512-3_13
- ISBN
  9783319895116, 9783319895123
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Journal Article] Dynamic expression and roles of Hes factors in neural development.2015
- Author(s)
  Kageyama R, Shimojo H, Imayoshi I.
- Journal Title
  
  Cell Tissue Res
  
  Volume: 359 Issue: 1 Pages: 125-133
- DOI
  10.1007/s00441-014-1888-7
- NAID
  120005615654
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22123002, KAKENHI-PROJECT-24240049, KAKENHI-PROJECT-24700354
[Journal Article] Visualization of Notch signaling oscillation in cells and tissues.2014
- Author(s)
  Shimojo H, Harima Y, Kageyama R.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1187 Pages: 169-179
- DOI
  10.1007/978-1-4939-1139-4_13
- NAID
  120005615653
- ISBN
  9781493911387, 9781493911394
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22123002, KAKENHI-PROJECT-24240049, KAKENHI-PROJECT-24700354, KAKENHI-PROJECT-26830010
[Journal Article] The roles and mechanism of ultradian oscillatory expression of the mouse Hes genes.2014
- Author(s)
  Harima Y, Imayoshi I, Shimojo H, Kobayashi T, Kageyama R.
- Journal Title
  
  Semin Cell Dev Biol.
  
  Volume: 34 Pages: 85-90
- DOI
  10.1016/j.semcdb.2014.04.038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22123002, KAKENHI-PROJECT-22687017, KAKENHI-PROJECT-24240049, KAKENHI-PROJECT-24700354, KAKENHI-PUBLICLY-25112511, KAKENHI-PROJECT-26440122, KAKENHI-PROJECT-26830010
[Journal Article] Genetic visualization of notch signaling in mammalian neurogenesis.2013
- Author(s)
  Imayoshi I, Shimojo H, Sakamoto M, Ohtsuka T, Kageyama R
- Journal Title
  
  Cell Mol Life Sci.
  
  Volume: 70 Issue: 12 Pages: 2045-57
- DOI
  10.1007/s00018-012-1151-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500390, KAKENHI-PUBLICLY-24116705, KAKENHI-PROJECT-24700354
[Presentation] Hes1-Neurog2-Tbr2 dynamics regulate the timing of neuronal differentiation via down-regulation of Notch signaling2022
- Author(s)
  Hiromi Shimojo and Ryoichiro Kageyama
- Organizer
  第45回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Gene expression dynamics regulating the timing of neuronal differentiation during mammalian neural development2020
- Author(s)
  Hiromi Shimojo
- Organizer
  第４３回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Gene expression dynamics regulate the timing of down-regulation of Notch signaling and neuronal differentiation.2020
- Author(s)
  Hiromi Shimojo
- Organizer
  第４３回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Gene expression dynamics regulating the timing of neuronal differentiation during mammalian neural development2019
- Author(s)
  Hiromi Shimojo
- Organizer
  第４２回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Gene expression dynamics regulating neuronal differentiation2019
- Author(s)
  Hiromi Shimojo
- Organizer
  第９２回日本生化学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis2019
- Author(s)
  Hiromi Shimojo
- Organizer
  第５２回日本発生生物学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Dynamic gene expressions during mammalian neural development2018
- Author(s)
  Hiromi Shimojo
- Organizer
  2018 Korea-Japan Joint Symposium on Neurodevelopment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Dynamic gene expressions during neural development2018
- Author(s)
  Hiromi Shimojo
- Organizer
  22nd Biennial Meeting of the International Society for Developmental Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06254
[Presentation] Dynamic gene expression during neural development2013
- Author(s)
  Hiromi Shimojo, Yukiko Harima, Yuki Maeda, Toshiyuki Ohtsuka and Ryoichiro Kageyama
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PUBLICLY-24116705
[Presentation] Dynamic expression of Notch ligand Dll1 during neural development2013
- Author(s)
  Hiromi Shimojo and Ryoichiro Kageyama
- Organizer
  The 61st NIBB conference: Cellular Community in Mammalian Embryogenesis
- Place of Presentation
  愛知県岡崎市
- Data Source
  KAKENHI-PROJECT-24700354
[Presentation] Dynamic expression of Notch ligand Dll1 during neural development2013
- Author(s)
  Hiromi Shimojo and Ryoichiro Kageyama
- Organizer
  The 61st NIBB conference: Cellular Community in Mammalian Embryogenesis
- Place of Presentation
  愛知県岡崎市
- Data Source
  KAKENHI-PUBLICLY-24116705
[Presentation] The significance of dynamic proneural gene expression in neural development2013
- Author(s)
  Hiromi Shimojo and Ryoichiro Kageyama
- Organizer
  Neuro 2013 Satellite Symposium: Molecular and Cellular Mechanisms of brain development and evloution
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PUBLICLY-24116705
[Presentation] Dynamic expression of Notch ligand Dll1 during neural development2013
- Author(s)
  下條博美
- Organizer
  第７回　Notchシグナル研究会
- Place of Presentation
  静岡県　三島市　国立遺伝学研究所
- Year and Date
  2013-02-14
- Data Source
  KAKENHI-PUBLICLY-24116705
[Presentation] The significance of dynamic proneural gene expression in neural development2013
- Author(s)
  Hiromi Shimojo and Ryoichiro Kageyama
- Organizer
  Neuro 2013 Satellite Symposium: Molecular and Cellular Mechanisms of brain development and evloution
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PROJECT-24700354
[Presentation] Dynamic gene expression during neural development2013
- Author(s)
  Hiromi Shimojo, Yukiko Harima, Yuki Maeda, Toshiyuki Ohtsuka, Hitoshi Miyachi and Ryoichiro Kageyama
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-24700354
[Presentation] Dynamic expression of Notch ligand Dll1 during neural development2012
- Author(s)
  下條博美
- Organizer
  Swiss-Japanese Developmental Biology Meeting
- Place of Presentation
  京都府　京都市　京都ガーデンパレス
- Year and Date
  2012-11-05
- Data Source
  KAKENHI-PUBLICLY-24116705
[Presentation] Dynamic expression of Notch ligand Dll1 during development
- Author(s)
  Hiromi Shimojo, Akihiro Isomura, Toshiyuki Ohtsuka, Hitoshi Miyachi and Ryoichiro Kageyama
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24700354
[Presentation] Dynamic expression of Notch ligand Dll1 during development
- Author(s)
  Hiromi Shimojo, Akihiro Isomura, Toshiyuki Otsuka, Hitoshi Miyachi, Hiroshi Kori and Ryoichiro Kageyama
- Organizer
  CDB Symposium 2015
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-23 – 2015-03-25
- Data Source
  KAKENHI-PROJECT-24700354
[Presentation] Dynamic expression of Notch ligand Dll1 during development
- Author(s)
  Hiromi Shimojo
- Organizer
  第１２０回日本解剖学会総会・全国学術集会／第９２回日本生理学会大会　合同大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24700354

1. 影山龍一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
2. 磯村彰宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 大塚俊之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Shimojo Hiromi 下條 博美

HIROMI Shimojo 下條 博美

Research Projects

Research Products

Co-Researchers

エピブラスト運命決定過程における多能性因子Nanogの時期特異的な機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular clock regulating the timing of cell fate determinationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞集団制御における隣接細胞間シグナル伝達速度の意義Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamic gene expression during mammalian neurogenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic transcriptional control of neural stem cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Daughter cells inherit YAP localization from mother cells in early preimplantation embryos.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biological Significance of the Coupling Delay in Synchronized Oscillations2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Real-time Bioluminescence Imaging of Notch Signaling Dynamics during Murine Neurogenesis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic control of neural stem cells by bHLH factors2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oscillatory control of Notch signaling in development2018

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Dynamic expression and roles of Hes factors in neural development.2015

Author(s)

Journal Title

DOI

NAID

Shimojo Hiromi 下條博美

HIROMI Shimojo 下條博美