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Yuzawa Satoru  湯澤 聡

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YUZAWA Satoru  湯澤 聡

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Researcher Number 40515029
Other IDs
Affiliation (Current) 2025: 国際医療福祉大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 国際医療福祉大学, 医学部, 講師
2016: 九州大学, 医学研究院, 共同研究員
2015: 九州大学, 医学(系)研究科(研究院), 研究員
2015: 九州大学, 医学研究院, 助教
2012 – 2014: 九州大学, 医学(系)研究科(研究院), 助教 … More
2011: 九州大学, 医学(系)研究科(研究院), 特任准教授
2011: 九州大学, 医学研究院, 特任准教授
2010: Kyushu University, 大学院・医学研究院, 学術研究員
2010: 九州大学, 生体防御医学研究所, 特任准教授
2009: Kyushu University, 生体防御医学研究所, 学術研究員 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Biological Sciences
Except Principal Investigator
Basic Section 56020:Orthopedics-related / Basic Section 48040:Medical biochemistry-related / Tumor biology
Keywords
Principal Investigator
X線結晶構造解析 / 分子認識 / 蛋白質 / 細胞極性 / シグナル伝達 / モチーフ / NMR / 天然変性蛋白質 / 酵素反応 / 基質特異性 … More / 酵素 / 微小管 / 翻訳後修飾 / タンパク質 / LGN / 細胞極性の形成 / TPRモチーフ / 蛋白質間相互作用 / 自己阻害状態 / 分子内相互作用 / タンパク質間相互作用 / 細胞内シグナル伝達 … More
Except Principal Investigator
軟骨形成 / 骨形成 / FGFシグナル / 細胞内シグナル伝達 / 細胞表面受容体 / アルツハイマー病 / ノックアウトマウス / TM2D2 / TM2D1 / TM2D3 / Notchシグナル / 細胞運動 / 浸潤・転移 / エンドサイトーシス / Girdin / ダイナミン Less
  • Research Projects

    (8 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (7 People)
  •  骨・軟骨形成における可溶型FGF受容体によるFGFシグナル調節機構の解明

    • Principal Investigator
      吉岡 広陽
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      International University of Health and Welfare
  •  Regulatory mechanisms of Notch receptor activation at the cell surface

    • Principal Investigator
      Kitagawa Motoo
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      International University of Health and Welfare
  •  Structural basis of the substrate specificity of the alpha-tubulin acetyltransferasePrincipal Investigator

    • Principal Investigator
      Yuzawa Satoru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyushu University
  •  Investigation of discrimination and activation of Dynamin 2 GTPase by Girdin

    • Principal Investigator
      Miyoshi Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      St. Marianna University School of Medicine
  •  細胞分裂に関連するタンパク質NuMAの動的構造解析と制御機構Principal Investigator

    • Principal Investigator
      湯澤 聡
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Structural analysis of the regulation of mitotic spindle orientation by the cell polarity protein LGNPrincipal Investigator

    • Principal Investigator
      YUZAWA Satoru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyushu University
  •  細胞分裂に関連するタンパク質NuMAの動的構造解析と制御機構Principal Investigator

    • Principal Investigator
      湯澤 聡 (湯沢 聡)
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Structural basis of polarity protein LGN in complex with its partner moleculesPrincipal Investigator

    • Principal Investigator
      YUZAWA Satoru
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyushu University

All 2022 2017 2015 2013 2012 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Ric-8A-mediated stabilization of the trimeric G protein subunit Gαi is inhibited by pertussis toxin-catalyzed ADP-ribosylation2017

    • Author(s)
      Kanako Chishiki, Sachiko Kamakura, Junya Hayase, Satoru Yuzawa, Hideki Sumimoto
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 483 Issue: 3 Pages: 941-945

    • DOI

      10.1016/j.bbrc.2017.01.036

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J04231, KAKENHI-PROJECT-14J05233, KAKENHI-PROJECT-26440033, KAKENHI-PROJECT-15K08309, KAKENHI-PROJECT-16K21221, KAKENHI-PLANNED-26111009
  • [Journal Article] Structural basis of cofactor-mediated stabilization and substrate recognition of the α-tubulin acetyltransferase αTAT12015

    • Author(s)
      Yuzawa S, Kamakura S, Hayase J, Sumimoto H
    • Journal Title

      Biochem J.

      Volume: 467 Issue: 2 Pages: 103-113

    • DOI

      10.1107/s2053230x14028143

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590385, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-26440033
  • [Journal Article] Structural basis of cofactor-mediated stabilization and substrate recognition of the α-tubulin acetyltransferase αTAT12015

    • Author(s)
      Satoru Yuzawa, Sachiko Kamakura, Junya Hayase and Hideki Sumimoto
    • Journal Title

      Biochemical Journal

      Volume: 467 Issue: 1 Pages: 103-113

    • DOI

      10.1042/bj20141193

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J05233, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-26440033, KAKENHI-PROJECT-26860193, KAKENHI-PROJECT-15K08309
  • [Journal Article] Ubiquitination of the heterotrimeric G protein α subunits Gαi2 and Gαq is prevented by the guanine nucleotide exchange factor Ric-8A2013

    • Author(s)
      Chishiki, K., Kamakura, S., Yuzawa, S., Hayase, J., Sumimoto, H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 435 Issue: 3 Pages: 414-419

    • DOI

      10.1016/j.bbrc.2013.04.103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570141, KAKENHI-PUBLICLY-24113718, KAKENHI-PROJECT-24590385
  • [Journal Article] Ubiquitination of the heterotrimeric G protein α subunits Gα i2 and Gαq is prevented by the guanine nucleotide exchange factor Ric-8A2013

    • Author(s)
      Kanako Chishiki, Sachiko Kamakura, Satoru Yuzawa, Junya Hayase, Hideki Sumimoto.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 435 Pages: 414-419

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Journal Article] 細胞極性タンパク質LGN とパートナー分子mInsc 複合体の認識機構2012

    • Author(s)
      湯澤 聡
    • Journal Title

      日本結晶学会誌

      Volume: 54 Pages: 206-212

    • NAID

      130002142912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Journal Article] 細胞極性タンパク質LGN と パートナー分子mInsc 複合体の認識機構2012

    • Author(s)
      湯澤聡
    • Journal Title

      日本結晶学会誌

      Volume: 54 Pages: 206-212

    • NAID

      130002142912

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24113718
  • [Journal Article] 細胞極性タンパク質LGNとパートナー分子mInsc複合体の認識機構2012

    • Author(s)
      湯澤聡
    • Journal Title

      日本結晶学会誌

      Volume: 54 Pages: 206-212

    • NAID

      130002142912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Journal Article] Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å resolution2012

    • Author(s)
      Shunsuke Matsumoto, Mayumi Igura, James Nyirenda, Masaki Matsumoto, Satoru Yuzawa, Nobuo Noda, Fuyuhiko Inagaki, Daisuke Kohda.
    • Journal Title

      Biochemistry

      Volume: 51 Pages: 4157-4166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Journal Article] Crystal structure of the C-terminal globular domain of oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75Å resolution.2012

    • Author(s)
      Matsumoto, S., Igura, M., Nyirenda, J., Matsumoto. M, Yuzawa, S., Noda, N., Inagaki, F., Kohda, D.
    • Journal Title

      Biochemistry

      Volume: 51 Issue: 20 Pages: 4157-4166

    • DOI

      10.1021/bi300076u

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370047, KAKENHI-PLANNED-21121003, KAKENHI-PUBLICLY-24113718
  • [Journal Article] Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)2011

    • Author(s)
      Satoru Yuzawa, Sachiko Kamakura, Yuko Iwakiri, Junya Hayase, Hideki Sumimoto.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 108 Pages: 19210-19215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Journal Article] Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)2011

    • Author(s)
      Yuzawa S, Kamakura S, Iwakiri, Y, Hayase J, Sumimoto H
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 108 Pages: 19210-19215

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22113515
  • [Journal Article] A conserved region between the TPR and activation domains of p67^<phox> participates in activation of the phagocyte NADPH oxidase2010

    • Author(s)
      Maehara Y, Miyano K, Yuzawa S, Akimoto R, Takeya R, Sumimoto H.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 31435-31445

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22113515
  • [Journal Article] A conserved region between the TPR and activation domains of p67^<phox> participates in activation of the phagocyte NADPH oxidase2010

    • Author(s)
      Maehara Y., Miyano K., Yuzawa S., Akimoto R., Takeya R., Sumimoto H.
    • Journal Title

      J .Biol.Chem. 285

      Pages: 31435-31445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] A conserved region between the TPR and activation domains of p67^<phox> participates in activation of the phagocyte NADPH oxidase2010

    • Author(s)
      Maehara Y, Miyano K, Yuzawa S, Akimoto R, Takeya R, Sumimoto H.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 31435-31445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] The domain organization of p67^<phox> a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.2009

    • Author(s)
      Yuzawa, S., Miyano, K., Honbou, K., Inagaki, F., Sumimoto, H.
    • Journal Title

      J.Innate Immun. 1

      Pages: 543-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] Crystal structures of free and ligand-bound focal adhesion targcting domain of Pyk2.2009

    • Author(s)
      Lulo, J., Yuzawa, S., Schlessinger, J.
    • Journal Title

      Biochem. Biophys. Res. Commun. 383

      Pages: 347-352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.2009

    • Author(s)
      Bae, J-H., Lew, D.E., Yuzawa, S., Tome, F., Lax, I., Schlessinger, J.
    • Journal Title

      Cell 138

      Pages: 514-524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] The selectivity of receptor tyrosine kinasc signaling is controlled by a secondary SH2 domain binding site.2009

    • Author(s)
      Bae, J-H., Lew, D.E. Yuzawa, S., Tome, F., Lax, I., Schlessinger, J.
    • Journal Title

      Cell 138

      Pages: 514-524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2.2009

    • Author(s)
      Lulo, J., Yuzawa, S., Schlessinger, J.
    • Journal Title

      Biochem .Biophys.Res.Commun. 383

      Pages: 347-352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Journal Article] The domain organization of p67^<phox>, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.2009

    • Author(s)
      Yuzawa, S., Miyano, K., Honbou, K., Inagaki, F., Sumimoto, H.
    • Journal Title

      J.Innate Immun. 1

      Pages: 543-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Presentation] Transmembrane 2 domain containing 3 (TM2D3) のin vitroおよびin vivoにおけるNotchシグナルへの関与2022

    • Author(s)
      増田渉、板橋匠美、梅宮敏文、岩間厚志、安島理恵子、三宅克也、ジャミヤンスレン ジャンバルドルジ、湯澤 聡、東 和彦、田丸淳、木曽 誠、松野 健治、相賀 裕美子、北川 元生
    • Organizer
      第44回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07374
  • [Presentation] TM2D群(TM2D1、TM2D2、TM2D3)のNotchシグナルにおける機能2022

    • Author(s)
      北川元生、Jambaldorj Jamiyansuren、湯澤聡、板橋匠美、梅宮敏文、岩間厚志、増田渉、三宅克也、相賀裕美子、安島理恵子
    • Organizer
      第12回国際医療福祉大学学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K07374
  • [Presentation] アダプタータンパク質LGNのTPRドメインによるスキャフォールドタンパク質Frmpd4/Preso1認識の構造基盤2015

    • Author(s)
      髙栁宏樹,湯澤聡,住本英樹
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会BMB2015
    • Place of Presentation
      神戸市
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26440033
  • [Presentation] α-チューブリンアセチル化酵素αTAT1のコファクターによる安定化の構造基盤2015

    • Author(s)
      湯澤聡,鎌倉幸子,早瀬純也,住本英樹
    • Organizer
      第15回日本蛋白質科学会年会
    • Place of Presentation
      徳島市
    • Year and Date
      2015-06-24
    • Data Source
      KAKENHI-PROJECT-26440033
  • [Presentation] 細胞極性タンパク質LGNのTPRドメインによるパートナー分子の多様な認識2012

    • Author(s)
      湯澤 聡,鎌倉 幸子,岩切 優子,早瀬 純也,住本 英樹
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Presentation] 細胞極性タンパク質LGNのTPRドメインによるパートナー分子の多様な認識2012

    • Author(s)
      湯澤 聡,鎌倉 幸子,岩切 優子,早瀬 純也,住本 英樹
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PUBLICLY-24113718
  • [Presentation] 細胞極性タンパク質LGN のTPR ドメインによるパートナー分子の多様な認識2012

    • Author(s)
      湯澤聡,鎌倉幸子,岩切優子,早瀬純也,住本英樹
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Presentation] 細胞極性関連タンパク質 Inscuteable とLGN との複合体のX 線結晶構造解析2011

    • Author(s)
      湯澤聡,鎌倉幸子,岩切優子,早瀬純也,住本英樹
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Presentation] 細胞極性関連タンパク質InscuteableとLGNとの複合体のX線結晶構造解析2011

    • Author(s)
      湯澤聡, 鎌倉幸子, 岩切優子, 早瀬純也, 住本英樹
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PUBLICLY-22113515
  • [Presentation] 細胞極性関連タンパク質InscuteableとLGNとの複合体のX線結晶構造解析2011

    • Author(s)
      湯澤 聡,鎌倉幸子,岩切優子,早瀬純也,住本英樹
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23570141
  • [Presentation] Nox2活性化におけるp67^<phox>のドメイン配置と作用機構2009

    • Author(s)
      湯澤聡, 宮野佳, 本坊和也, 稲垣冬彦, 住本英樹
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Presentation] Nox2活性化におけるp67^<phox>のドメイン配置と作用機構2009

    • Author(s)
      湯沢聡, 宮野佳, 本坊和也, 稲垣冬彦, 住本英樹
    • Organizer
      第82回 日本生化会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Presentation] The domain organization of p67^<phox> a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.2009

    • Author(s)
      Yuzawa, S., Miyano, K., Honbou, K., Inagaki, F., Sumimoto, H.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21770116
  • [Presentation] The domain organization of p67^<phox>, a protein required for activation of the superoxide-producing NADPH oxidase in hagocytes2009

    • Author(s)
      Yuzawa, S., Miyano, K., Honbou, K., Inagaki, F., Sumimoto, H.
    • Organizer
      第32回 日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21770116
  • 1.  Miyoshi Hiroshi (80322519)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  ENOMOTO Atsushi (20432255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Kitagawa Motoo (40262026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  増田 渉 (00623464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  吉岡 広陽 (50523411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  鎌倉 幸子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  神田 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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