Ookubo Youichirou 大久保陽一郎

… Alternative Names

OKUBO Yoichiro 大久保陽一郎

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Researcher Number	40516267
Other IDs	https://orcid.org/0000-0002-7079-4454
Affiliation (Current)	2024: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 病理診断科, 医長 2024: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 医長 2024: 東邦大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 病理診断科, 医長 2021 – 2022: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 病理診断科, 医長 2015 – 2022: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 医長 2013 – 2014: 東邦大学, 医学部, 講師 2012: 東邦大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Human pathology / Infectious disease medicine Except Principal Investigator Basic Section 49020:Human pathology-related
Keywords	Principal Investigator カルチノイド / paraganglioma / neuroendocrine tumor / CoGNET / neuroendocrine carcinoma / neuroendocrine neoplasm / 神経内分泌癌 / 神経内分泌腫瘍 / 感染防御機構 / 多核巨細胞 … More / クリプトコックス / 肺胞 / ＣＤ４ / PGK1 / CD4 / 樹状細胞ワクチン / Pgk1 / 肉芽腫 / DNAマイクロアレイ / Cryptococcus neoformans / Cryptococcus gattii / 血行動態 / ＰＴＴＭ / 腫瘍塞栓 / 内膜肥厚 / フィブリン血栓 / 肺高血圧 / 肺動脈 / 肺腫瘍塞栓症 / 胃癌 / PTTM … More Except Principal Investigator miRNA / 神経内分泌腫瘍 / 膵臓 / microRNA / mTOR阻害薬 / マイクロアレイ / 免疫組織化学 / ソマトスタチンアナログ / mTOR阻害剤 Less

Elucidation of the mechanism of drug resistance acquisition and development of innovative therapies for PanNETs focusing on miRNAs
- Principal Investigator
  
  平林健一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Toyama
Development of novel therapeutics for pancreatic neuroendocrine tumor targeting microRNA
- Principal Investigator
  
  Hirabayashi Kenichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Toyama
  Tokai University
Elucidating metastasis mechanisms and prognostic factors in neuroendocrine tumorsPrincipal Investigator
- Principal Investigator
  
  大久保陽一郎
- Project Period (FY)
  2017 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kanagawa Cancer Center Research Institute
Systemic studies of murine pulmonary cryptococcosis: Candidate virulence factors against cryptococciPrincipal Investigator
- Principal Investigator
  
  Okubo Yoichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kanagawa Cancer Center Research Institute
  Toho University
Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: pathophysiological analysis in autopsy casesPrincipal Investigator
- Principal Investigator
  
  OKUBO Yoichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Toho University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine tumours,5th ed (Composite gangliocytoma/neuroma and neuroendocrine tumour (CoGNET))2022
- Author(s)
  Guido Rindi , Sylvia L. Asa , Anthony J. Gill , Talia L. Fuchs , Silvia Uccella , Yoichiro Okubo
- Publisher
  WHO (World Health Organization) / IARC (International Agency for Research on Cancer)
- Data Source
  KAKENHI-PROJECT-17K08713
[Book] Applied gene histopathology: identification of Fusarium species in FFPE tissue sections by in situ hybridization2013
- Author(s)
  Okubo Y, Shinozaki M, Wakayama M, Nakayama H, Sasai D, Ishiwatari T, Nemoto T, Naobumi T, Shibuya K.
- Total Pages
  215
- Publisher
  Hindawi Publishing Corporation
- Data Source
  KAKENHI-PROJECT-24790364
[Book] Applied gene histopathology : identification of Fusarium species in FFPE tissue sections by in situ hybridization. Hindawi Publishing Corporation. Methods in Molecular Biology.2013
- Author(s)
  Okubo Y, Shinozaki M, Wakayama M, Nakayama H, Sasai D, Ishiwatari T, Nemoto T, Naobumi T, Shibuya K
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Significance of non-standardized magnetic resonance imaging abnormalities and subsequent targeted prostate cancer biopsy for pathologists: A retrospective observational study2022
- Author(s)
  Okubo Yoichiro、Yamamoto Yayoi、Terao Hideyuki、Suzuki Takahisa、Koizumi Mitsuyuki、Yoshioka Emi、Washimi Kota、Sato Shinya、Yokose Tomoyuki、Kishida Takeshi、Miyagi Yohei
- Journal Title
  
  Pathology - Research and Practice
  
  Volume: 240 Pages: 154188-154188
- DOI
  10.1016/j.prp.2022.154188
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Diagnostic significance of reassessment of prostate biopsy specimens by experienced urological pathologists at a high-volume institution2022
- Author(s)
  Okubo Yoichiro、Yamamoto Yayoi、Sato Shinya、Yoshioka Emi、Suzuki Masaki、Washimi Kota、Osaka Kimito、Suzuki Takahisa、Yokose Tomoyuki、Kishida Takeshi、Miyagi Yohei
- Journal Title
  
  Virchows Archiv
  
  Volume: - Issue: 5 Pages: 979-987
- DOI
  10.1007/s00428-022-03272-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09422, KAKENHI-PROJECT-17K08713
[Journal Article] Clinicopathological and genetic analyses of small cell neuroendocrine carcinoma of the prostate: Histological features for accurate diagnosis and toward future novel therapies2022
- Author(s)
  Ida Arika、Okubo Yoichiro、Kasajima Rika、Washimi Kota、Sato Shinya、Yoshioka Emi、Osaka Kimito、Suzuki Takahisa、Yamamoto Yayoi、Yokose Tomoyuki、Kishida Takeshi、Miyagi Yohei
- Journal Title
  
  Pathology - Research and Practice
  
  Volume: 229 Pages: 153731-153731
- DOI
  10.1016/j.prp.2021.153731
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Signet-ring Cell Carcinoma Component as an Indicator of Anaplastic Lymphoma Kinase Mutations in Colorectal Cancer2021
- Author(s)
  Nukada Suguru、Okubo Yoichiro、Shiozawa Manabu、Yoshioka Emi、Suzuki Masaki、Washimi Kota、Kawachi Kae、Sato Sumito、Hiroshima Yukihiko、Rino Yasushi、Yokose Tomoyuki、Masuda Munetaka
- Journal Title
  
  Journal of the Anus, Rectum and Colon
  
  Volume: 5 Issue: 2 Pages: 167-172
- DOI
  10.23922/jarc.2020-068
- NAID
  130008031059
- ISSN
  2432-3853
- Year and Date
  2021-04-28
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Clinicopathological Analysis of the ISUP Grade Group And Other Parameters in Prostate Cancer: Elucidation of Mutual Impact of the Various Parameters2021
- Author(s)
  Okubo Yoichiro、Sato Shinya、Osaka Kimito、Yamamoto Yayoi、Suzuki Takahisa、Ida Arika、Yoshioka Emi、Suzuki Masaki、Washimi Kota、Yokose Tomoyuki、Kishida Takeshi、Miyagi Yohei
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11
- DOI
  10.3389/fonc.2021.695251
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713, KAKENHI-PROJECT-20K09422
[Journal Article] Histopathological study of carcinoma showing thymus-like differentiation (CASTLE)2020
- Author(s)
  Okubo Y, Sakai M, Yamazaki H, Sugawara Y, Samejima J, Yoshioka E, Suzuki M, Washimi K, Kawachi H, Hayashi H, Ito H, Iwasaki H, Yokose T
- Journal Title
  
  The Malaysian Journal of Pathology
  
  Volume: 42 Pages: 259-265
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Occult Thyroid Carcinoma without Malignant Thyroid Gland Findings during Preoperative Examination: Report of Three Cases2020
- Author(s)
  Toda Soji、Iwasaki Hiroyuki、Suganuma Nobuyasu、Okubo Yoichiro、Hayashi Hiroyuki、Masudo Katsuhiko、Nakayama Hirotaka、Masuda Munetaka
- Journal Title
  
  Case Reports in Endocrinology
  
  Volume: 2020 Pages: 1-6
- DOI
  10.1155/2020/4249067
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Membrane type 1 matrix metalloproteinase regulates anaplastic thyroid carcinoma cell growth and invasion into the collagen matrix2020
- Author(s)
  Yoshida Tatsuya、Suganuma Nobuyasu、Sato Shinya、Toda Soji、Nakayama Hirotaka、Masudo Katsuhiko、Okubo Yoichiro、Hayashi Hiroyuki、Yokose Tomoyuki、Koshikawa Naohiko、Rino Yasushi、Iwasaki Hiroyuki、Miyagi Yohei、Masuda Munetaka、Hoshino Daisuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 4 Pages: 1195-1200
- DOI
  10.1016/j.bbrc.2020.06.043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329
[Journal Article] Primary solitary fibrous tumour of the prostate: A case report and literature review2020
- Author(s)
  Okubo Y, Nukada S, Shibata Y, Osaka K, Yoshioka E, Suzuki M, Washimi K, Kawachi K, Kishida K, Yokose T, Miyagi Y
- Journal Title
  
  The Malaysian Journal of Pathology
  
  Volume: 42 Pages: 449-453
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Clinicopathological and molecular features of hereditary leiomyomatosis and renal cell cancer-associated renal cell carcinomas2020
- Author(s)
  Furuya M, Iribe Y, Nagashima Y, Kambe N, Ohe C, Kinoshita H, Sato C, Kishida T, Okubo Y, Numakura K, Nanjo H, Nakaigawa N, Makiyama K, Hasumi H, Iwashita H, Ohta J, Kitamura H, Nakajima T, Yoshida T, Nakagawa M, Tanaka R, Yao M
- Journal Title
  
  Journal of Clinical Pathology
  
  Volume: 73 Issue: 12 Pages: 819-825
- DOI
  10.1136/jclinpath-2020-206548
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713, KAKENHI-PROJECT-19K08784, KAKENHI-PROJECT-19K09717, KAKENHI-PROJECT-20K07395
[Journal Article] Two cases of thyroid gland invasion by upper mediastinal carcinoma2019
- Author(s)
  Yamazaki Haruhiko、Iwasaki Hiroyuki、Okubo Yoichiro、Suganuma Nobuyasu、Masudo Katsuhiko、Nakayama Hirotaka、Rino Yasushi、Masuda Munetaka
- Journal Title
  
  Endocrinology, Diabetes & Metabolism Case Reports
  
  Volume: 2019
- DOI
  10.1530/edm-19-0028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] A Case of Long-Term Survival after Multidisciplinary Treatment for Gastrointestinal Neuroendocrine Carcinoma2019
- Author(s)
  Yotsumoto H, Yamamoto N, Kamiya M, Inoue H, Washimi K, Okubo Y, Oike N, Yokose T, Rino Y, Masuda M, Morinaga S.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 46 Pages: 2270-2272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Gangliocytic paraganglioma: An overview and future perspective2019
- Author(s)
  Okubo Yoichiro
- Journal Title
  
  World Journal of Clinical Oncology
  
  Volume: 10 Issue: 9 Pages: 300-302
- DOI
  10.5306/wjco.v10.i9.300
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Diagnosis, Pathological Findings, and Clinical Management of Gangliocytic Paraganglioma: A Systematic Review2018
- Author(s)
  Okubo Yoichiro、Yoshioka Emi、Suzuki Masaki、Washimi Kota、Kawachi Kae、Kameda Yoichi、Yokose Tomoyuki
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 8
- DOI
  10.3389/fonc.2018.00291
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Hereditary leiomyomatosis and renal cell cancer without cutaneous manifestations in two Japanese siblings2018
- Author(s)
  Noguchi Go、Furuya Mitsuko、Okubo Yoichiro、Nagashima Yoji、Kato Ikuma、Matsumoto Kana、Tanaka Reiko、Hisasue Shin-ichi、Yao Masahiro、Kishida Takeshi
- Journal Title
  
  International Journal of Urology
  
  Volume: 25 Issue: 9 Pages: 832-835
- DOI
  10.1111/iju.13760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08713, KAKENHI-PROJECT-17K08745, KAKENHI-PROJECT-17K11162, KAKENHI-PROJECT-16K19085
[Journal Article] Gangliocytic Paraganglioma Is Often Misdiagnosed as Neuroendocrine Tumor G1.2017
- Author(s)
  Okubo Y
- Journal Title
  
  Archives of Pathology and Laboratory Medicine
  
  Volume: 141 Issue: 10 Pages: 1309-1309
- DOI
  10.5858/arpa.2017-0102-le
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Gangliocytic Paraganglioma: a Diagnostic Pitfall of Rare Neuroendocrine Tumor.2017
- Author(s)
  Okubo Y
- Journal Title
  
  Endocrine Pathology
  
  Volume: 28 Issue: 2 Pages: 186-186
- DOI
  10.1007/s12022-017-9481-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] Risk factors associated with the progression and metastases of hindgut neuroendocrine tumors: a retrospective study.2017
- Author(s)
  Okubo Y, Kasajima R, Suzuki M, Miyagi Y, Motohashi O, Shiozawa M, Yoshioka E, Washimi K, Kawachi K, Kameda Y, Yokose T
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Issue: 1 Pages: 769-769
- DOI
  10.1186/s12885-017-3769-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08713
[Journal Article] A linking bridge between histopathological analysis and molecular assay in microbiology2017
- Author(s)
  Okubo Y
- Journal Title
  
  Malaysian Journal of Pathology
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Duodenal Rare Neuroendocrine Tumor: Clinicopathological Characteristics of Patients with Gangliocytic Paraganglioma.2016
- Author(s)
  Okubo Y, Yokose T, Motohashi O, Miyagi Y, Yoshioka E, Suzuki M, Washimi K, Kawachi K, Nito M, Nemoto T, Shibuya K, Kameda Y.
- Journal Title
  
  Gastroenterology Research and Practice
  
  Volume: 5257312 Pages: 1-10
- DOI
  10.1155/2016/5257312
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] The clinicopathological significance of angiogenesis in hindgut neuroendocrine tumors obtained via an endoscopic procedure.2016
- Author(s)
  Okubo Y, Motohashi O, Nakayama N, Nishimura K, Kasajima R, Miyagi Y, Shiozawa M, Yoshioka E, Suzuki M, Washimi K, Kawachi K, Nito M, Kameda Y, Yokose T.
- Journal Title
  
  Diagnostic Pathology
  
  Volume: 11 Issue: 1
- DOI
  10.1186/s13000-016-0580-5
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Neuroendocrine Differentiation in Breast Cancer: Clinicopathological Significance of Bcl-2 Positive Solid Papillary Carcinoma.2016
- Author(s)
  Okubo Y, Okubo T, Okubo Y, Ishiwatari T.
- Journal Title
  
  Case Reports in Medicine
  
  Volume: 9501410 Pages: 1-6
- DOI
  10.1155/2016/9501410
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Evasion of Innate Immune Responses by the Highly Virulent Cryptococcus gattii by Altering Capsule Glucuronoxylomannan Structure2016
- Author(s)
  Urai M, Kaneko Y, Ueno K, Okubo Y, Aizawa T, Fukazawa H, Sugita T, Ohno H, Shibuya K, Kinjo Y and Miyazaki Y
- Journal Title
  
  Front Cell Infect Microbiol
  
  Volume: 5 Pages: 101-101
- DOI
  10.3389/fcimb.2015.00101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15383, KAKENHI-PROJECT-26860774, KAKENHI-PROJECT-25461526, KAKENHI-PROJECT-15K21644
[Journal Article] Genomic analysis for single nucleotide polymorphisms (Asp299Gly and Thr399lle) in Japanese patients with invasive aspergillosis2015
- Author(s)
  Aki K, Okubo Y, Nanjo H, Ishiwatari T, Nihonyanagi Y, Tochigi N, Wakayama M, Nemoto T, Fukutake K, Shinozaki M, Hori Y, Masuda H, Shibuya K
- Journal Title
  
  Japanese Journal of Infectious Diseases
  
  Volume: In press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Gangliocytic paraganglioma: a multi-institutional retrospective study in Japan.2015
- Author(s)
  Okubo Y, Nemoto T, Wakayama M, Tochigi N, Shinozaki M, Ishiwatari T, Aki K, Tsuchiya M, Aoyama H, Katsura K, Fujii T, Nishigami T, Yokose T, Ohkura Y, Shibuya K
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Issue: 1 Pages: 1-9
- DOI
  10.1186/s12885-015-1308-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Tracheal leiomyoma resected with endobronchial electrocautery snare2015
- Author(s)
  Nakamura Y, Hata Y, Koezuka S, Makino T, Otsuka H, Sato F, Sasamoto S, Okubo Y, Nemoto T, Shibuya K, Iyoda A
- Journal Title
  
  Journal of Bronchology and Interventional Pulmonology
  
  Volume: 22 Issue: 1 Pages: 90-93
- DOI
  10.1097/lbr.0000000000000107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Histological study of chronic pulmonary aspergillosis2015
- Author(s)
  Tochigi N, Ishiwatari T, Okubo Y, Ando T, Shinozaki M, Aki K, Gocho K, Hata Y, Murayama SY, Wakayama M, Nemoto T, Hori Y, Shibuya K
- Journal Title
  
  Diagn Pathol
  
  Volume: 10 Issue: 1 Pages: 153-153
- DOI
  10.1186/s13000-015-0388-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860250, KAKENHI-PROJECT-26860774
[Journal Article] A case of postoperative hepatic granuloma presumptively caused by surgical staples/clipping materials.2015
- Author(s)
  Nihon-Yanagi Y, Ishiwatari T, Otsuka Y, Okubo Y, Tochigi N, Wakayama M, Nemoto T, Watanabe M, Kaneko H, Sumino Y, Shibuya K.
- Journal Title
  
  Diagnostic Pathology
  
  Volume: 10 Issue: 1 Pages: 1-5
- DOI
  10.1186/s13000-015-0291-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Effects of habitual exercise and dietary restriction on intrahepatic and periepididymal fat accumulation in Zucker fatty rats.2015
- Author(s)
  Kurosaka Y, Shiroya Y, Yamauchi H, Kaneko T, Okubo Y, Shibuya K, Minato K.
- Journal Title
  
  BMC Research Notes
  
  Volume: 8 Issue: 1 Pages: 121-121
- DOI
  10.1186/s13104-015-1063-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870553, KAKENHI-PROJECT-26860774
[Journal Article] Remodeling of the pulmonary artery induced by metastatic gastric carcinoma: a histopathological analysis of 51 autopsy cases. BMC Cancer2014
- Author(s)
  Ishiwatari T, Okubo Y, Tochigi N, Wakayama M, Nemoto T, Kobayashi J, Shinozaki M, Aki K, Sasai D, Yamamoto Y, Nakayama H, Shibuya K
- Journal Title
  
  BMC Cancer
  
  Volume: 14 Issue: 1 Pages: 14-14
- DOI
  10.1186/1471-2407-14-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Comparison between the location and the histomorphological/immunohistochemical characteristics of noninvasive neoplasms of the ampulla of Vater2014
- Author(s)
  Yamamoto Y, Nemoto T, Okubo Y, Nihonyanagi Y, Ishiwatari T, Takuma K, Tochigi N, Okano N, Wakayama M, Igarashi Y, Shibuya K
- Journal Title
  
  Hum Pathol
  
  Volume: 45 Issue: 9 Pages: 1910-7
- DOI
  10.1016/j.humpath.2014.05.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460460, KAKENHI-PROJECT-26860774
[Journal Article] 肺アスペルギルス症の病理学的考察2014
- Author(s)
  栃木直文, 大久保陽一郎, 澁谷和俊
- Journal Title
  
  呼吸器内科
  
  Volume: 26 Pages: 22-26
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860774
[Journal Article] Histopathological evaluation of the efficacy of antifungals for experimental Trichosporon bloodstream infection2013
- Author(s)
  Sasai D, Okubo Y, Ishiwatari T, Sugita T, Kaneko T, Murayama SY, Shimamura T, Shinozaki M, Hasegawa C, Mitsuda A, Tochigi N, Wakayama M, Nemoto T, Shibuya K
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 66 Pages: 133-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Development of a peptide nucleic acid probe to Trichosporon species and identification of trichosporonosis by use of in situ hybridization in formalin-fixed and paraffin-embedded (FFPE) sections2013
- Author(s)
  Shinozaki M, Okubo Y, Sasai D, Nakayama H, Murayama SY, Ide T, Wakayama M, Ishiwatari T, Tochigi N, Nemoto T, Shibuya K
- Journal Title
  
  J Clin Microbiol
  
  Volume: 51 Issue: 1 Pages: 295-298
- DOI
  10.1128/jcm.02221-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Histopathological evaluation of the efficacy of antifungals for experimental Trichosporon bloodstream infection.2013
- Author(s)
  Sasai D, Okubo Y, Ishiwatari T, Sugita T, Kaneko T, Murayama SY, Shimamura T, Shinozaki M, Hasegawa C, Mitsuda A, Tochigi N, Wakayama M, Nemoto T, Shibuya K
- Journal Title
  
  Japanese Journal of Infectious Diseases
  
  Volume: 66 Pages: 133-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs2013
- Author(s)
  Shimodaira K, Okubo Y, Ochiai E, Nakayama H, Katano H, Wakayama M, Shinozaki M, Ishiwatari T, Sasai D, Tochigi N, Nemoto T, Saji T, Kamei K, Shibuya K
- Journal Title
  
  Respir Res
  
  Volume: 13(online journal) Issue: 1 Pages: 103-103
- DOI
  10.1186/1465-9921-13-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Pathophysiological implication of reversed CT halo sign in invasive pulmonary mucormycosis: a rare case report2013
- Author(s)
  Okubo Y, Ishiwatari T, Izumi H, Sato F, Aki K, Sasai D, Ando T, Shinozaki M, Natori K, Tochigi N, Wakayama M, Hata Y, Nakayama H, Nemoto T, Shibuya K
- Journal Title
  
  Diagnostic Pathology
  
  Volume: 8 Issue: 1 Pages: 82-82
- DOI
  10.1186/1746-1596-8-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Histopathological Imolications of Aspergillus Infection in Lung2013
- Author(s)
  Tochigi N, Okubo Y, Ando T, Wakayama M, Shinozaki M, Gocho K, Hata Y, Ishiwatari T, Nemoto T, Shibuya K
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2013 Pages: 809798-809798
- DOI
  10.1155/2013/809798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Development and evaluation of nucleic acid-based techniques for an auxiliary diagnosis of invasive fungal infections in formalin-fixed and paraffin-embedded (FFPE) tissues2013
- Author(s)
  Shinozaki M, Okubo Y, Sasai D, Nakayama H, Ishiwatari T, Murayama S, Tochigi N, Wakayama M, Nemoto T, Shibuya K
- Journal Title
  
  Med Mycol J
  
  Volume: 53 Pages: 241-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] Development and evaluation of nucleic acid-based techniques for an auxiliary diagnosis of invasive fungal infections in formalin-fixed and paraffin-embedded (FFPE) tissues.2013
- Author(s)
  Shinozaki M, Okubo Y, Sasai D, Nakayama H, Ishiwatari T, Murayama S, Tochigi N, Wakayama M, Nemoto T, Shibuya K
- Journal Title
  
  Medical Mycology Journal
  
  Volume: 53 Pages: 241-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Journal Article] How histopathology can contribute to an understanding of defense mechanisms against cryptococci.2013
- Author(s)
  Okubo Y, Tochigi N, Wakayama M, Shinozaki M, Nakayama H, Ishiwatari T, Shimodaira K, Nemoto T, Ohno H, Kaneko Y, Makimura K, Uchida K, Miyazaki Y, Yamaguchi H, Shibuya K
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2013 Pages: 465319-465319
- DOI
  10.1155/2013/465319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790364
[Presentation] 膵pancreatic polypeptide産生神経内分泌腫瘍の臨床病理学的検討2022
- Author(s)
  平林健一、福村由紀、田尻琢磨、内藤嘉紀、大久保陽一郎、高梨由美、中村直哉
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07470
[Presentation] 当院におけるASC-USの現状とそこからみえる細胞像2019
- Author(s)
  酒井麻衣、内山亜弥、那須隆二、杉﨑加奈、能條潤、北村和久、岩撫成子、大久保陽一郎、加藤久、横瀬智之
- Organizer
  第60回日本臨床細胞学会総会
- Data Source
  KAKENHI-PROJECT-17K08713
[Presentation] 前立腺生検における生検前MRI の臨床病理学的意義2019
- Author(s)
  大久保　陽一郎、野口剛、宮城　洋平、吉岡　恵美、鈴木　理樹、鷲見　公太、河内　香江、岸田健、亀田　陽一、横瀬　智之
- Organizer
  第108回　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08713
[Presentation] 網羅的文献調査を基盤としたgangliocytic paraganglioma 263例の解析2018
- Author(s)
  大久保　陽一郎、吉岡　恵美、鈴木　理樹、鷲見　公太、河内　香江、亀田　陽一、横瀬　智之
- Organizer
  第64回　日本病理学会　秋季特別総会
- Data Source
  KAKENHI-PROJECT-17K08713
[Presentation] 消化管神経内分泌腫瘍における浸潤・転移機構の解明ならびに予後予測因子の確立2017
- Author(s)
  大久保　陽一郎、吉岡　恵美、鷲見　公太、河内　香江、塩澤　学、宮城　洋平、笹田　哲朗、成松　宏人、横瀬　智之、亀田　陽一
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08713
[Presentation] クリプトコックス剖検例の病理組織学的解析2015
- Author(s)
  石渡誉郎, 二本柳康宏, 大久保陽一郎, 栃木直文, 若山恵, 根本哲生, 澁谷和俊
- Organizer
  第36回関東医真菌懇話会
- Place of Presentation
  札幌(北海道)
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] マウス肺を用いたクリプトコックス感染症に対する組織学的解析：感染防御機構の観点から2015
- Author(s)
  大久保陽一郎, 大野秀明, 上野圭吾, 石渡誉郎, 栃木直文, 若山恵, 根本哲生, 金城雄樹, 宮崎義継, 澁谷和俊
- Organizer
  第104回日本病理学会総会名古屋
- Place of Presentation
  名古屋(愛知)
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] Histopathological study of autopsy subjects with cryptococcosis2015
- Author(s)
  Ishiwatari T, Nihonyanagi Y, Ejima K, Okubo Y, Tochigi N, Shinozaki M, Wakayama M, Nemoto T, Shibuya K
- Organizer
  19th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Melbourne(Australia)
- Year and Date
  2015-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] 剖検例を用いたクリプトコックス症の病理学的解析2015
- Author(s)
  石渡誉郎, 二本柳康博, 大久保陽一郎, 栃木直文, 若山恵, 根本哲生, 澁谷和俊
- Organizer
  第104回日本病理学会総会名古屋
- Place of Presentation
  名古屋
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] Identification of dimorphic yeast in FFPE tissue sections by in situ hybridization using PNA probes2015
- Author(s)
  Okubo Y, Aki K, Shinozaki M, Nihonyanagi Y, Ejima K, Ishiwatari, T, Tochigi N, Mitsuda A, Wakayama M, Nemoto T, Hori Y, Shibuya k
- Organizer
  19th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2015-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] Histopathological study of murine pulmonary cryptococcosis: candidate virulence factors against Cryptococci2015
- Author(s)
  Okubo Y, Ohno H, Ueno K, Aki K, Shinozaki M, Nihonyanagi Y, Ejima K, Ishiwatari T, Tochigi N, Mitsuda A, Wakayama M, Nemoto T, Hori Y, Kinjo Y, Miyazaki Y, Kamei K, Shibuya K
- Organizer
  19th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Melbourne(Australia)
- Year and Date
  2015-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] クリプトコックス剖検例の病理組織学的解析2015
- Author(s)
  石渡誉郎, 二本柳康博, 大久保陽一郎, 定本聡太, 小林純子, 江嶋梢, 栃木直文, 篠崎稔, 若山恵, 根本哲生, 澁谷和俊
- Organizer
  第59回日本医真菌学会総会・学術集会
- Place of Presentation
  札幌(北海道)
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] マクロファージの貪食を指標としたCryptococcus gattii感染病態の評価2014
- Author(s)
  壇辻百合香, 大野秀明, 梅山隆, 上野圭吾, 大久保陽一郎, 田辺公一, 名木稔, 山越智, 金城雄樹, 杉田隆, 澁谷和俊, 宮﨑義継
- Organizer
  第58回日本医真菌学会総会・学術集会
- Place of Presentation
  ワークピア横浜・横浜産貿ホール(神奈川)
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] クリプトコックスの莢膜多糖による免疫回避機構の解析及びその制御法の開発2014
- Author(s)
  金城雄樹, 上野圭吾, 浦井誠, 金子幸弘, 大久保陽一郎, 清水公徳, 大野秀明, 亀井克彦, 川本進, 澁谷和俊, 宮﨑義継
- Organizer
  第58回日本医真菌学会総会・学術集会
- Place of Presentation
  ワークピア横浜・横浜産貿ホール(神奈川)
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] Cryptococcus gattii株における病原性発現機構の解明2014
- Author(s)
  大久保陽一郎, 大野秀明, 安藝恭子, 篠崎稔, 石渡誉郎, 栃木直文, 若山恵, 根本哲生, 下平佳代子, 中山晴雄, 田辺公一, 山越智, 金子幸弘, 宮﨑義継, 亀井克彦, 澁谷和俊
- Organizer
  第58回日本医真菌学会総会・学術集会
- Place of Presentation
  ワークピア横浜・横浜産貿ホール(神奈川)
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] 高病原性Cryptococcus gattiの感染防衛に寄与する樹状細胞ワクチン2014
- Author(s)
  上野圭吾, 金城雄樹, 大久保陽一郎, 浦井　誠, 金子幸弘, 大野秀明, 亀井克彦、澁谷和俊, 宮崎義継
- Organizer
  第63回日本感染症学会東日本地方会総会学術集会　第61回日本化学療法学会東日本支部総会　合同学会
- Place of Presentation
  東京ドームホテル (東京)
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] 高病原性cryptcoccus gattii の感染防衛に寄与する樹状細胞ワクチンの作用2014
- Author(s)
  上野圭吾, 金城雄樹, 大久保陽一郎, 清水公徳, 金子幸弘, 浦井誠, 川本進, 亀井克彦, 大野秀明, 澁谷和俊, 宮﨑義継
- Organizer
  第58回日本医真菌学会総会・学術集会
- Place of Presentation
  ワークピア横浜・横浜産貿ホール(神奈川)
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-26860774
[Presentation] 癌細胞関連肺動脈構造改変に関する病理学的研究第2013
- Author(s)
  石渡誉郎、大久保陽一郎、根本哲生、若山恵、山本慶郎、笹井大督、栃木直文、長谷川千花子、密田亜希、横瀬智之、島田英昭、五十嵐良典、渋谷和俊
- Organizer
  102回日本病理学会総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2013-06-07
- Data Source
  KAKENHI-PROJECT-24790364
[Presentation] 癌細胞関連肺動脈構造改変に関する病理学的研究
- Author(s)
  石渡誉郎, 大久保陽一郎, 根本哲生, 若山　恵, 山本慶郎, 笹井大督, 栃木直文, 長谷川千花子, 密田亜希, 横瀬智之, 島田英昭, 五十嵐良典, 渋谷和俊
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-24790364

1. Hirabayashi Kenichi (60514388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 宮沢正樹 (10554818)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 大池信之 (20286777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 福村由紀 (90407312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 田尻琢磨 (60327913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 内藤嘉紀 (50465712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. SATO Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. WASHIMI Kota

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. KINJO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. MINATO Kumiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. SHIROYA Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. YAMAUCHI Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 栃木直文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 渋谷和俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 若山恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 上野圭吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 黒坂裕香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ookubo Youichirou 大久保 陽一郎

OKUBO Yoichiro 大久保 陽一郎

Research Projects

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Co-Researchers

Elucidation of the mechanism of drug resistance acquisition and development of innovative therapies for PanNETs focusing on miRNAs

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Development of novel therapeutics for pancreatic neuroendocrine tumor targeting microRNA

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Elucidating metastasis mechanisms and prognostic factors in neuroendocrine tumorsPrincipal Investigator

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Systemic studies of murine pulmonary cryptococcosis: Candidate virulence factors against cryptococciPrincipal Investigator

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Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: pathophysiological analysis in autopsy casesPrincipal Investigator

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[Book] WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine tumours,5th ed (Composite gangliocytoma/neuroma and neuroendocrine tumour (CoGNET))2022

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[Book] Applied gene histopathology: identification of Fusarium species in FFPE tissue sections by in situ hybridization2013

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[Book] Applied gene histopathology : identification of Fusarium species in FFPE tissue sections by in situ hybridization. Hindawi Publishing Corporation. Methods in Molecular Biology.2013

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[Journal Article] Significance of non-standardized magnetic resonance imaging abnormalities and subsequent targeted prostate cancer biopsy for pathologists: A retrospective observational study2022

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[Journal Article] Diagnostic significance of reassessment of prostate biopsy specimens by experienced urological pathologists at a high-volume institution2022

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[Journal Article] Clinicopathological and genetic analyses of small cell neuroendocrine carcinoma of the prostate: Histological features for accurate diagnosis and toward future novel therapies2022

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[Journal Article] Signet-ring Cell Carcinoma Component as an Indicator of Anaplastic Lymphoma Kinase Mutations in Colorectal Cancer2021

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[Journal Article] Clinicopathological Analysis of the ISUP Grade Group And Other Parameters in Prostate Cancer: Elucidation of Mutual Impact of the Various Parameters2021

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[Journal Article] Histopathological study of carcinoma showing thymus-like differentiation (CASTLE)2020

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Ookubo Youichirou 大久保陽一郎

OKUBO Yoichiro 大久保陽一郎