HAGA Yoshimi 芳賀淑美

… Alternative Names

芳賀淑美ハガヨシミ

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Researcher Number	40525789
Other IDs	https://orcid.org/0000-0001-7861-617X
Affiliation (Current)	2025: 公益財団法人がん研究会, がんプレシジョン医療研究センター分析生化学研究部, 主任研究員
Affiliation (based on the past Project Information) *help	2023: 公益財団法人がん研究会, がんプレシジョン医療研究センターがんオーダーメイド医療開発プロジェクト, 主任研究員 2017 – 2021: 公益財団法人がん研究会, がんプレシジョン医療研究センターがんオーダーメイド医療開発プロジェクト, 研究員 2016: 公益財団法人がん研究会, ゲノムセンター, 研究員 2015: 公益財団法人がん研究会, その他部局等, 研究員 2014: 理化学研究所, 糖鎖代謝学研究チーム, 特別研究員 2011: The Institute of Physical and Chemical Research, 研究員
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator 質量分析 / 糖鎖 / プロテオーム / 癌 / グライコプロテオミクス / GLUT4 Except Principal Investigator α-フェトプロテイン / イメージング / フコース / 極性輸送 / アピカル / 糖鎖 / AFP

包括的組織Oグライコプロテオミクスによるがん特異的糖鎖の作動原理解明Principal Investigator
- Principal Investigator
  
  芳賀淑美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Japanese Foundation for Cancer Research
Development of profiling method for cancer-specific O-GlcNAcylationPrincipal Investigator
- Principal Investigator
  
  HAGA Yoshimi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Japanese Foundation for Cancer Research
Development of profiling method for O-glycopeptidesPrincipal Investigator
- Principal Investigator
  
  HAGA Yoshimi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Japanese Foundation for Cancer Research
Profiling of N-glycan structure on GLUT4 glucose transporter critical for intracellular traffickingPrincipal Investigator
- Principal Investigator
  
  HAGA Yoshimi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Japanese Foundation for Cancer Research
Validation of hypothesis for "fucose-dependent polarized transport system" by visualizing specific glycoforms of glycoproteins
- Principal Investigator
  
  SUZUKI Tadashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research
特定の糖タンパク質視覚化を目指した蛍光プローブの開発と検出法の確立Principal Investigator
- Principal Investigator
  
  芳賀淑美
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation Book

[Book] Glycoform Imaging. In Glycoscience: Biology and Medicine. (N. Taniguchi, T. Endo, G. W. Hart, P. Seeberger, C-H. Wong eds.)2014
- Author(s)
  Yoshimi Haga and Tadashi Suzuki
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25650041
[Book] FRETを使った特定糖タンパク質の可視化 (pp186-191) 第三の生命鎖研究の最前線　糖鎖の機能・作動原理と疾患　実験医学（門松　健治、遠藤　玉夫、岡　昌吾、北川　裕之　編）2013
- Author(s)
  芳賀　淑美、鈴木　匡
- Total Pages
  225
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-25650041
[Journal Article] Frontiers in mass spectrometry-based clinical proteomics for cancer diagnosis and treatment2023
- Author(s)
  Yoshimi Haga, Yuriko Minegishi, Koji Ueda
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 5 Pages: 1783-1791
- DOI
  10.1111/cas.15731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05759, KAKENHI-PROJECT-23K05704, KAKENHI-PROJECT-23K21392
[Journal Article] Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth2023
- Author(s)
  Nagai Kenichiro、Muto Yui、Miura Saori、Takahashi Kazuto、Naruse Yu、Hiruta Ryo、Hashimoto Yuko、Uzuki Miwa、Haga Yoshimi、Fujii Risa、Ueda Koji、Kawaguchi Yasushi、Fujii Masazumi、Kitazume Shinobu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 9 Pages: 105128-105128
- DOI
  10.1016/j.jbc.2023.105128
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16448, KAKENHI-PROJECT-23K05704
[Journal Article] Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques2022
- Author(s)
  Haga Yoshimi、Ueda Koji
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 39 Issue: 2 Pages: 303-313
- DOI
  10.1007/s10719-022-10043-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06553
[Journal Article] Siblings with MAN1B1-CDG Showing Novel Biochemical Profiles2021
- Author(s)
  Okamoto Nobuhiko、Ohto Tatsuyuki、Enokizono Takashi、Wada Yoshinao、Kohmoto Tomohiro、Imoto Issei、Haga Yoshimi、Seino Junichi、Suzuki Tadashi
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 11 Pages: 3117-3117
- DOI
  10.3390/cells10113117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06553, KAKENHI-PROJECT-18H02894
[Journal Article] Identification of Multisialylated LacdiNAc Structures as Highly Prostate Cancer Specific Glycan Signatures on PSA.2019
- Author(s)
  Haga, Y., Uemura, M., Baba, S., Inamura, K., Takeuchi, K., Nonomura, N., and Ueda, K.
- Journal Title
  
  Analytical chemistry
  
  Volume: 91 Issue: 3 Pages: 2247-2247
- DOI
  10.1021/acs.analchem.8b04829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-17K15097
[Journal Article] Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown2016
- Author(s)
  Tarhan, Y. E., Kato, T., Jang, M., Haga, Y., Ueda, K., Nakamura, Y. and Park, J. H.
- Journal Title
  
  Neoplasia
  
  Volume: 18 Issue: 5 Pages: 265-72
- DOI
  10.1016/j.neo.2016.03.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710007, KAKENHI-PROJECT-15K18509, KAKENHI-PROJECT-16KT0116
[Journal Article] 特定の糖鎖構造をもつ標的タンパク質の蛍光イメージングと細胞内動態解析2014
- Author(s)
  芳賀　淑美、鈴木　匡
- Journal Title
  
  化学と生物
  
  Volume: 52 Pages: 100-105
- NAID
  130004808945
- Data Source
  KAKENHI-PROJECT-25650041
[Journal Article] Use of transmembrane FRET to investigate the internalization of glycosylated proteins.2014
- Author(s)
  Yoshimi Haga and Tadashi Suzuki
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1174 Pages: 225-230
- DOI
  10.1007/978-1-4939-0944-5_15
- ISBN
  9781493909438, 9781493909445
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25650041
[Presentation] Fast and Ultrasensitive Glycoform Profiling Technology by Supercritical Fluid Chromatography-Tandem Mass Spectrometry2023
- Author(s)
  Yoshimi Haga
- Organizer
  26th International Glycoconjugate Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05704
[Presentation] A novel glycoform profiling technology SFC-Erexim for rapid and precise quality control of therapeutic antibodies2021
- Author(s)
  Yoshimi Haga and Koji Ueda
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] Global Immunopeptidomics by Differential Ion Mobility Mass Spectrometry for Identification of Patient Specific HLA-Presented Antigens Directly from Clinical Tissues2021
- Author(s)
  Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi and Koji Ueda
- Organizer
  HUPO ReCONNECT 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] エクソソーム内包変異タンパク質検出による新たな腎癌バイオマーカー開発2021
- Author(s)
  箱崎勇治、峯岸ゆり子、芳賀叔美、山田雄太、久米春喜、植田幸嗣
- Organizer
  第8回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] エクソソーム中変異タンパク質パネルによる新規腎癌診断技術開発2021
- Author(s)
  箱崎勇治、山田雄太、峯岸ゆり子、芳賀淑美、久米春喜、植田幸嗣
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] Structural characterization of N-glycan microheterogeneity on PD-L1 for development of novel companion diagnostics2020
- Author(s)
  Yoshimi Haga and Koji Ueda
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] Multisialylated LacdiNAc structures on PSA (PSA G-Index) as a highly specificity-enhanced secondary biomarker for prostate cancer2019
- Author(s)
  Yoshimi Haga, Motohide Uemura, Kengo Takeuchi, Norio Nonomura, Koji Ueda
- Organizer
  HUPO2019
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] 前立腺癌特異的PSA糖鎖構造の同定による新規な前立腺癌診断アルゴリズムPSA G-Indexの構築2019
- Author(s)
  芳賀淑美、植村元秀、赤松秀輔、稲村健太郎、竹内賢吾、小川修、野々村祝夫、植田幸嗣
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K06553
[Presentation] 前立腺癌特異的PSA糖鎖構造の同定による高特異度前立腺癌マーカーPSA G-indexの開発2018
- Author(s)
  芳賀淑美、植村元秀、稲村健太郎、竹内賢吾、野々村祝夫、植田幸嗣
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15097
[Presentation] Rapid profiling of prostate cancer-specific PSA glycoforms as a specificity-enhanced secondary biomarker2018
- Author(s)
  Yoshimi Haga, Motohide Uemura, Kentaro Inamura, Kengo Takeuchi, Norio Nonomura and Koji Ueda
- Organizer
  HUPO 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15097
[Presentation] Identification of highly prostate cancer-specific PSA glyco-isoforms (PSA G-index)2017
- Author(s)
  Yoshimi Haga, Motohide Uemura, Norio Nonomura and Koji Ueda
- Organizer
  International Symposium"Systems Glycobiology and Beyond"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15097
[Presentation] Identification of highly prostate cancer-specific PSA glyco-isoforms (PSA G-index)2017
- Author(s)
  Yoshimi Haga, Motohide Uemura, Norio Nonomura and Koji Ueda
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15097
[Presentation] Development of specificity-enhanced PSA screening by rapid glycoform analysis2016
- Author(s)
  Yoshimi Haga, Naomi Saichi, Motohide Uemura and Koji Ueda
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Place of Presentation
  マウイ島、アメリカ
- Year and Date
  2016-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18509
[Presentation] Development of rapid glycoform analysis for specificity-enhanced PSA screening2016
- Author(s)
  Yoshimi Haga, Motohide Uemura and Koji Ueda
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K18509
[Presentation] Development of specificity-enhanced PSA by rapid glycan profiling2015
- Author(s)
  Yoshimi Haga, Naomi Saichi and Koji Ueda
- Organizer
  HUPO 2015
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2015-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18509
[Presentation] Glycoform imaging: use of transmembrane FRET to investigate the internalization of glycosylated proteins.2014
- Author(s)
  Yoshimi Haga, Kumiko Ishii, Kayo Hibino, Yasuhi Sako, Yukishige Ito, Naoyuki Taniguchi, and Tadashi Suzuki
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2014-11-17
- Data Source
  KAKENHI-PROJECT-25650041
[Presentation] Glycoform imaging: use of transmembrane FRET to investigate the internalization of glycosylated proteins.2014
- Author(s)
  Yoshimi Haga, Kumiko Ishii, Kayo Hibino, Yasuhi Sako, Yukishige Ito, Naoyuki Taniguchi, and Tadashi Suzuki
- Organizer
  2014 SFG & JSCR Joint Meeting Satellite Symposium II Glycans in Neuroscience
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-25650041
[Presentation] 特定の糖鎖構造を持つ標的タンパク質の蛍光イメージングと細胞内動態解析2013
- Author(s)
  芳賀淑美、石井久美子、日比野佳代、佐甲靖志、伊藤幸成、谷口直之、鈴木　匡
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25650041
[Presentation] Imaging of glycoforms as a sweet tool to visualize the dynamics of specific glycoprpoteins.2013
- Author(s)
  Yoshimi Haga, Kumiko Ishii, Kayo Hibino, Yasushi Sako, Yukishige Ito, Naoyuki Taniguchi, and Tadashi Suzuki
- Organizer
  The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology
- Place of Presentation
  理化学研究所（和光）
- Data Source
  KAKENHI-PROJECT-25650041
[Presentation] Imaging of glycoforms as a sweet tool to visualize the dynamics of specific glycoproteins.2013
- Author(s)
  Yoshimi Haga, Kumiko Ishii, Kayo Hibino, Yasushi Sako, Yukishige Ito, Naoyuki Taniguchi, and Tadashi Suzuki
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology The Second Symposium
- Place of Presentation
  理化学研究所（和光）
- Data Source
  KAKENHI-PROJECT-25650041
[Presentation] 標的タンパク質の糖鎖修飾蛍光イメージングと細胞内動態解析2013
- Author(s)
  芳賀淑美、石井久美子、日比野佳代、佐甲靖志、伊藤幸成、谷口直之、鈴木　匡
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪）
- Data Source
  KAKENHI-PROJECT-25650041

1. SUZUKI Tadashi (90345265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. UEDA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 峯岸ゆり子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 高橋一人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAGA Yoshimi 芳賀 淑美

芳賀 淑美 ハガ ヨシミ

Research Projects

Research Products

Co-Researchers

包括的組織Oグライコプロテオミクスによるがん特異的糖鎖の作動原理解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of profiling method for cancer-specific O-GlcNAcylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of profiling method for O-glycopeptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Profiling of N-glycan structure on GLUT4 glucose transporter critical for intracellular traffickingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Validation of hypothesis for "fucose-dependent polarized transport system" by visualizing specific glycoforms of glycoproteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

特定の糖タンパク質視覚化を目指した蛍光プローブの開発と検出法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Glycoform Imaging. In Glycoscience: Biology and Medicine. (N. Taniguchi, T. Endo, G. W. Hart, P. Seeberger, C-H. Wong eds.)2014

Author(s)

Publisher

Data Source

[Book] FRETを使った特定糖タンパク質の可視化 (pp186-191) 第三の生命鎖研究の最前線 糖鎖の機能・作動原理と疾患 実験医学（門松 健治、遠藤 玉夫、岡 昌吾、北川 裕之 編）2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Frontiers in mass spectrometry-based clinical proteomics for cancer diagnosis and treatment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Siblings with MAN1B1-CDG Showing Novel Biochemical Profiles2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Multisialylated LacdiNAc Structures as Highly Prostate Cancer Specific Glycan Signatures on PSA.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown2016

Author(s)

Journal Title

DOI

Data Source

HAGA Yoshimi 芳賀淑美

芳賀淑美ハガヨシミ

[Book] FRETを使った特定糖タンパク質の可視化 (pp186-191) 第三の生命鎖研究の最前線　糖鎖の機能・作動原理と疾患　実験医学（門松　健治、遠藤　玉夫、岡　昌吾、北川　裕之　編）2013