Kitade Mitsuteru 北出光輝

Researcher Number	40526795
Affiliation (based on the past Project Information) *help	2019: 奈良県立医科大学, 医学部, 研究員 2018: 奈良県立医科大学, 医学部, 博士研究員 2016 – 2017: 奈良県立医科大学, 医学部, 学内講師 2014 – 2016: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology / Medical pharmacy
Keywords	Principal Investigator NOTCH / 幹細胞 / 肝前駆細胞 / NOTCH1 / 肝再生 Except Principal Investigator 肝線維化 / 肝癌 / アンジオテンシン受容体阻害薬 / 肝臓学 / ヒアルロン酸ミセル … More / 新規マーカー / 腸内細菌 / エンドトキシン / 肝硬変 / 血管新生 / DPPⅣ阻害剤 / DPPIV阻害剤 / 非アルコール性脂肪肝炎 / PAI-1 / DPP4阻害剤 / PAI-1阻害剤 / SGLT-2阻害剤 / DPP-Ⅳ阻害剤 / ARB / 生活習慣病 / NASH / ウルソデオキシコール酸 / farnesoid X receptor / FXR / OCT1 / 胆汁酸 / 選択的NOTCH1阻害薬 / 肝前駆細胞 / 肝再生 Less

Development of therapeutic method to suppress liver disease progression by drug repositioning
- Principal Investigator
  
  Yoshiji Hitoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Identification of novel treatment and biomarkers based on pharmacokinetics in patients with hepatocellular carcinoma
- Principal Investigator
  
  Namisaki Tadashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nara Medical University
Development of new therapeutic approaches against chronic liver diseases with combination of hepatic progenitor cells and clinical available agents
- Principal Investigator
  
  Yoshiji Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Establishment of a new liver regeneration therapy by suppression of NOTCH1Principal Investigator
- Principal Investigator
  
  Kitade Mitsuteru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Establishment of new treatment targeting lifestyle diseases and coagulation fibrinolytic system related to the development of NASH
- Principal Investigator
  
  Noguchi Ryuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University

All 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Gut dysbiosis associated with clinical prognosis of patients with primary biliary cholangitis.2020
- Author(s)
  Furukawa M, Moriya K, Nakayama J, Inoue T, Momoda R, Kawaratani H, Namisaki T, Sato S, Douhara A, Kaji K, Kitade M, Shimozato N, Sawada Y, Saikawa S, Takaya H, Kitagawa K, Akahane T, Mitoro A, Yamao J, Tanaka Y, Yoshiji H.
- Journal Title
  
  Hepatol Res.
  
  Volume: 4 Issue: 7 Pages: 840-852
- DOI
  10.1111/hepr.13509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] Combining probiotics and an angiotensin-II type 1 receptor blocker has beneficial effects on hepatic fibrogenesis in a rat model of non-alcoholic steatohepatitis.2019
- Author(s)
  Sawada Y, Kawaratani H, Kubo T, Fujinaga Y, Furukawa M, Saikawa S, Sato S, Seki K, Takaya H, Okura Y, Kaji K, Shimozato N, Mashitani T, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yamao J, Yoshiji H.
- Journal Title
  
  Hepatol Res.
  
  Volume: 49 Issue: 3 Pages: 404-418
- DOI
  10.1111/hepr.13281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.2018
- Author(s)
  Kaji K, Nishimura N, Seki K, Sato S, Saikawa S, Nakanishi K, Furukawa M, Kawaratani H, Kitade M, Moriya K, Namisaki T, Yoshiji H.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 142 Issue: 8 Pages: 17121722-17121722
- DOI
  10.1002/ijc.31193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model2018
- Author(s)
  Seki K, Kitade M, Nishimura N, Kaji K, Asada K, Namisaki T, Moriya K, Kawaratani H, Okura Y, Takaya H, Sawada Y, Sato S, Nakanishi K, Yoshiji H.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 47 Pages: 28638-51
- DOI
  10.18632/oncotarget.25587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] von Willebrand factor is a useful biomarker for liver fibrosis and prediction of hepatocellular carcinoma development in patients with hepatitis B and C.2018
- Author(s)
  Takaya H, Kawaratani H, Tsuji Y, Nakanishi K, Saikawa S, Sato S, Sawada Y, Kaji K, Okura Y, Shimozato N, Kitade M, Akahane T, Moriya K, Namisaki T, Mitoro A, Matsumoto M, Fukui H, Yoshiji H
- Journal Title
  
  United European Gastroenterol J.
  
  Volume: 6 Issue: 9 Pages: 1401-1409
- DOI
  10.1177/2050640618779660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438, KAKENHI-PROJECT-16K10580
[Journal Article] Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats.2018
- Author(s)
  Nishimura N, Kaji K, Kitade M, Aihara Y, Sato S, Seki K, Sawada Y, Takaya H, Okura Y, Kawaratani H, Moriya K, Namisaki T, Mitoro A, Yoshiji H
- Journal Title
  
  BMC Cancer.
  
  Volume: 18 Issue: 1 Pages: 164-171
- DOI
  10.1186/s12885-018-5099-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein.2018
- Author(s)
  Saikawa S, Kaji K, Nishimura N, Seki K, Sato S, Nakanishi K, Kitagawa K, Kawaratani H, Kitade M, Moriya K, Namisaki T, Mitoro A, Yoshiji H.
- Journal Title
  
  Cancer Letters
  
  Volume: 434 Pages: 120-129
- DOI
  10.1016/j.canlet.2018.07.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity.2017
- Author(s)
  Kaji K, Takaya H, Saikawa S, Furukawa M, Sato S, Kawaratani H, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 23 Issue: 47 Pages: 83358366-83358366
- DOI
  10.3748/wjg.v23.i47.8355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09438
[Journal Article] Clinical significance of the Scheuer histological staging system for primary biliary cholangitis in Japanese patients.2017
- Author(s)
  Namisaki T, Moriya K, Kitade M, Kawaratani H, Takeda K, Okura Y, Takaya H, Nishimura N, Seki K, Kaji K, Sato S, Sawada Y, Yamao J, Mitoro A, Uejima M, Mashitani T, Shimozato N, Nakanishi K, Furukawa M, Saikawa S, Kubo T, Yoshiji H.
- Journal Title
  
  Eur J Gastroenterol Hepatol.
  
  Volume: 29 Pages: 23-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08077
[Journal Article] Effect of combined farnesoid X receptor agonist and angiotensin Ⅱtipe 1 receptor blocker on hepatic fibrosis.2017
- Author(s)
  Namisaki T. Moriya K, Kitade M, Takeda K, Kaji K, Okura Y, Shimozato N. Sato S, Nishimura N, Seki K, Kawaratani H, Takaya H, Sawada Y, Akahane T, Saikawa S, Nakanishi K, Kubo T, Furukawa M, Noguchi R, Asada K, Kitagawa K, Ozutsumi T, Tsuji Y, Kaya H Yoshiji
- Journal Title
  
  Hepatol commun.
  
  Volume: 1 Issue: 9 Pages: 928945-928945
- DOI
  10.1002/hep4.1104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09438, KAKENHI-PROJECT-15K08077
[Journal Article] Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis.2016
- Author(s)
  Okura Y,Yoshiji H.
- Journal Title
  
  Hepatol Res
  
  Volume: Dec28 Issue: 12 Pages: 1317-1328
- DOI
  10.1111/hepr.12860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461017, KAKENHI-PROJECT-26461018, KAKENHI-PROJECT-15K08077
[Journal Article] The relationship between hepatic progenitor cell-mediated liver regeneration and non-parenchymal cells.2016
- Author(s)
  Kitade M, Kaji K, Yoshiji H
- Journal Title
  
  Hepatol Res.
  
  Volume: Feb 19 Issue: 12 Pages: 1187-1193
- DOI
  10.1111/hepr.12682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461017, KAKENHI-PROJECT-26860523
[Journal Article] Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis.2016
- Author(s)
  Namisaki T, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Nishimura N, Takeda K, Okura Y, Kawaratani H, Takaya H, Seki K, Yoshiji H.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 51 Pages: 162-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis.2016
- Author(s)
  Namisaki T, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Nishimura N, Takeda K, Okura Y, Kawaratani H, Takaya H, Seki K, Yoshiji H
- Journal Title
  
  Ｊｏｕｎａｌ　ｏｆ　Ｇａｓｔｒｏｅｎｔｅｒｏｌｏｇｙ
  
  Volume: ５１ Issue: 2 Pages: 162-72
- DOI
  10.1007/s00535-015-1104-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08077, KAKENHI-PROJECT-26461017
[Journal Article] DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis.2016
- Author(s)
  Asada K, Aihara Y, Takaya H, Noguchi R, Namisaki T, Moriya K, Uejima M, Kitade M, Mashitani T, Takeda K, Kawaratani H, Okura Y, Kaji K, Douhara A, Sawada Y, Nishimura N, Seki K, Mitoro A, Yamao J, Yoshiji H.
- Journal Title
  
  World J Hepatol.
  
  Volume: 8 Issue: 28 Pages: 1194-1194
- DOI
  10.4254/wjh.v8.i28.1194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats.2016
- Author(s)
  Nishimura N, Kitade M, Noguchi R, Namisaki T, Moriya K, Takeda K, Okura Y, Aihara Y, Douhara A, Kawaratani H, Asada K, Yoshiji H.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats2016
- Author(s)
  Nishimura N, Kitade M, Noguchi R, Namisaki T, Moriya K, Takeda K, Okura Y, Aihara Y, Douhara A, Kawaratani H, Asada K, Yoshiji H
- Journal Title
  
  J Gastroenterol.
  
  Volume: Mar 29 Issue: 12 Pages: 1141-1149
- DOI
  10.1007/s00535-016-1200-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461017
[Journal Article] Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model.2015
- Author(s)
  Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Kaji K, Aihara Y, Nishimura N, Takeda K, Okura Y, Kawaratani H, Fukui H.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 11 Pages: 1693-1700
- NAID
  40020982272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Combination of sorafenib and angiotensin-II receptor blocker attenuates preneoplastic lesion development in a non-diabetic rat model of steatohepatitis.2014
- Author(s)
  Yoshiji H, Noguchi R, Namisaki T, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49 Issue: 10 Pages: 1421-1429
- DOI
  10.1007/s00535-013-0906-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461017
[Presentation] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity2019
- Author(s)
  Takaya H, Kaji K, Saikawa S, Furukawa M, Sato S, Sawada Y, Kawaratani H, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H
- Organizer
  EASL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Rifaximin alleviates endotoxemia with improvement of intestinal hyperpermeability and minor changes in fecal microbiota in cirrohotic patients with hepatic encephalopathy2018
- Author(s)
  Kaji K, Saikawa S, Takaya H, Sato S, Kitade M, Moriya K, Namisaki T, Akahane T, Yoshiji H
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity2018
- Author(s)
  Takaya H, Kaji K, Saikawa S, Furukawa M, Sato S, Sawada Y, Kawaratani H, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H
- Organizer
  EASL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Ratio of Von Willebrand Factor to ADAMTS13 is a Novel Potential Biomarker for Early Diagnosis of HCC2018
- Author(s)
  Takaya H, Namisaki T, Kitade M, Kaji K, Shimozato N, Akahane T, Moriya K, Kawaratani H, Sawada Y, Seki K, Sato S, Nakanishi K, Yoshiji H
- Organizer
  APASL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Moderate alcohol consumption protects against fatty liver in males2018
- Author(s)
  Akahane T, Namisaki T, Kitade M, Kaji K, Takaya H, Shimozato N, Sato S, Yoshiji H
- Organizer
  EASL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Biochemical response to ursodeoxycholic acid predicts histologic primary biliary cholangitis progression2018
- Author(s)
  Fujinaga Y, Namisaki T, Moriya K, Kitade M, Kawaratani H, Kaji K, Okura Y, Seki K, Takaya H, Sawada Y, Akahane T, Nishimura N, Sato S, Shimozato N, Saikawa S, Nakanishi K, Kubo T, Furukawa M, Yoshiji H
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] Identification of von willebrand factor-to-ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma in patients with liver cirrhosis2018
- Author(s)
  Takaya H, Namisaki T, Kaji K, Kitade M, Tsuji Y, Fujinaga Y, Furukawa M, Nakanishi K, Seki K, Sato S, Sawada Y, Saikawa S, Shimozato N, Kawaratani H, Asada K, Moriya K, Akahane T, Yoshiji H
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Biochemical response to ursodeoxycholic acid predicts histologic primary ciliary cholangitis progression2018
- Author(s)
  Namisaki T, Fujinaga Y, Moriya K, Kitade M, Kaji K, Kawaratani H, Seki K, Takaya H, Sato S, Sawada Y, Akahane T, Yoshji H
- Organizer
  EASL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] Beneficial effects of combined farnesoid X receptor agonist(INT747) and dipeptidyl peptidase-4 inhibitor(sitagliptin) on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis2017
- Author(s)
  Shimozato N, Namisaki T, Moriya K, Kitade M, Takeda K, Kawaratani H, Kaji K, Okura Y, Takaya H, Sawada Y, Nishimura N, Sato S, Saikawa S, Seki K, Furukawa M, Nakanishi K, Kubo T, Yoshiji H
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] ADAMTS13 deficiency exacerbates acute liver failure with enhanced VWF accumulation and hepatic inflammation in mice.2017
- Author(s)
  Takaya H, Kaji K, Kitade M, Seki K, Saikawa S, Nishimura N, Sato S, Sawada Y, Okura Y, Kawaratani H, Akahane T, Moriya K, Namisaki T, Mitoro A, Yoshiji H
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09438
[Presentation] Beneficial effects of combined farnesoid X receptor agonist(INT747) and dipeptidyl peptidase-4 inhibitor(sitagliptin) on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis2017
- Author(s)
  Shimozato N, Namisaki T, Moriya K, Kitade M, Takeda K, Kawaratani H, Kaji K, Okura Y, Takaya H, Sawada Y, Nishimura N, Sato S, Saikawa S, Seki K, Furukawa M, Nakanishi K, Kubo T, Yoshiji H
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] 肝線維化モデルにおける新規NOTCH1選択的阻害剤を用いた肝再生治療の試み2017
- Author(s)
  北出　光輝
- Organizer
  日本消化器病学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2017-04-22
- Data Source
  KAKENHI-PROJECT-26860523
[Presentation] DPP4阻害薬及びアンギオテンシンⅡ受容体拮抗薬併用による肝病態進展抑制効果2016
- Author(s)
  大倉康志、浪崎正、野口隆一、守屋圭、北出光輝、竹田幸祐、瓦谷英人、相原洋祐、西村典久、佐藤慎哉、澤田保彦、関建一郎、増谷剛、鍛治孝祐、吉治仁志
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26461017
[Presentation] DPP4阻害薬及びアンギオテンシンII受容体拮抗薬併用による肝病態進展抑制効2016
- Author(s)
  大倉康志、浪崎正、野口隆一、守屋圭、北出光輝、竹田幸祐、瓦谷英人、相原洋祐、西村典久、佐藤慎哉、澤田保彦、関建一郎、増谷剛、鍛冶孝佑、吉治仁志
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] Antifibrotic effects of combined treatment with Farnesoid X receptor agonist and angiotensin-II type1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis2016
- Author(s)
  Tadashi Namisaki, Yasushi Okura, Shinya Sato, Ryuichi Noguchi, Kei Moriya, Mitsuteru Kitade, Kosuke Takeda, Yosuke Aihara, Norihisa Nishimura, Yasuhiko Sawada, Kenichiro Seki, Hideto Kawaratani, Kosuke Kaji, Hitoshi Yoshiji.
- Organizer
  ヨーロッパ肝臓学会
- Place of Presentation
  バルセロナ　スペイン
- Year and Date
  2016-04-13
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] Impact of the combination of dipeptidyl peptidase IV inhibitor and angiotensin-Ⅱtype 1 receptor blocker on hepatocarcinogenesis in a rat model of nonalcoholic steatohepatitis2016
- Author(s)
  Okura Y, Namisaki T, Noguchi R, Takeda K, Moriya K, Kitade M, Nishimura N, Sato S, Sawada Y, Kawaratani H, Seki K, Kaji K, Yoshiji H
- Organizer
  EASL
- Place of Presentation
  Spain Barcelona
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461017
[Presentation] Antifirotic effects of combined treatment with farnesoid X receptor agonist and angiotensin-Ⅱtype1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis2016
- Author(s)
  Namisaki T, Okura Y, Sato S, Noguchi R, Moriya K, Kitade M, Takeda K, Nishimura N, Sawada Y, Seki K, Kawaratani H, Kaji K, Yoshiji H
- Organizer
  EASL
- Place of Presentation
  Spain Barcelona
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461017
[Presentation] 糖尿病ラットにおけるSGL T2阻害薬の肝線維化抑制効果と作用機序2016
- Author(s)
  西村典久、北出光輝、吉治仁志
- Organizer
  日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26461017
[Presentation] Combination treatment of dipeptidyl peptidase IV inhibitor and angiotensin-II type 1 receptor blocker attenuates progression of nonalcoholic steatohepatitis in rats2016
- Author(s)
  Shinya Sato, Tadashi Namisaki, Kosuke Kaji, Norihisa Nishimura, Yasushi Okura, Ryuichi Noguchi, Kosuke Takeda, Kei Moriya, Mitsuteru Kitade, Kenichiro Seki, Hiroaki Takaya, Hideto Kawaratani, Yasuhiko Sawada, Naotaka Shimozato, Keisuke Nakanishi, Hitoshi Yoshiji
- Organizer
  アメリカ肝臓学会
- Place of Presentation
  ボストン　US
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] 糖尿病発症ラットにおける非環式レチノイドとアンギオテンシンII受容体拮抗薬の併用による肝発癌抑制効果2015
- Author(s)
  西村典久、北出光輝、野口隆一、吉治仁志
- Organizer
  第24回日本がん転移学会学術集会総会
- Place of Presentation
  シティプラザ大阪
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] アンジオテンシンⅡ制御による肝線維化の抑制と肝再生の促進.
- Author(s)
  北出光輝、吉治仁志、福井博
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26461017

1. Yoshiji Hitoshi (40336855)

# of Collaborated Projects: 4 results

# of Collaborated Products: 38 results
2. Namisaki Tadashi (20526850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. Noguchi Ryuichi (30423908)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. Moriya Kei (40526852)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
5. Nishimura Norihisa

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
6. MATSUMOTO MASANORI (60316081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MASHITANI TSUYOSHI (20401929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 鍛治孝祐 (20623490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results

Kitade Mitsuteru 北出 光輝

Research Projects

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Development of therapeutic method to suppress liver disease progression by drug repositioning

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Identification of novel treatment and biomarkers based on pharmacokinetics in patients with hepatocellular carcinoma

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Development of new therapeutic approaches against chronic liver diseases with combination of hepatic progenitor cells and clinical available agents

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Establishment of a new liver regeneration therapy by suppression of NOTCH1Principal Investigator

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Establishment of new treatment targeting lifestyle diseases and coagulation fibrinolytic system related to the development of NASH

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[Journal Article] Gut dysbiosis associated with clinical prognosis of patients with primary biliary cholangitis.2020

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[Journal Article] Combining probiotics and an angiotensin-II type 1 receptor blocker has beneficial effects on hepatic fibrogenesis in a rat model of non-alcoholic steatohepatitis.2019

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[Journal Article] Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.2018

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[Journal Article] Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model2018

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[Journal Article] von Willebrand factor is a useful biomarker for liver fibrosis and prediction of hepatocellular carcinoma development in patients with hepatitis B and C.2018

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[Journal Article] Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats.2018

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[Journal Article] Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein.2018

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[Journal Article] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity.2017

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[Journal Article] Clinical significance of the Scheuer histological staging system for primary biliary cholangitis in Japanese patients.2017

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[Journal Article] Effect of combined farnesoid X receptor agonist and angiotensin Ⅱtipe 1 receptor blocker on hepatic fibrosis.2017

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Kitade Mitsuteru 北出光輝