Sakata Souhei 坂田宗平

… Alternative Names

SAKATA Souhei 坂田宗平

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Researcher Number	40528006
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 大阪医科薬科大学, 医学部, 准教授 2021 – 2023: 大阪医科薬科大学, 医学部, 准教授 2018 – 2020: 大阪医科大学, 医学部, 准教授 2015 – 2017: 大阪医科大学, 医学部, 講師 2016: 大阪大学, 医学(系)研究科(研究院), 招へい教員 … More 2013 – 2014: 大阪大学, 医学(系)研究科(研究院), 招へい教員 2012: 大阪大学, 医学(系)研究科(研究院), 研究員 2012: 大阪大学, 大学院・医学系研究科, 招へい研究員 2011: 大阪大学, 医学(系)研究科(研究院), 招へい研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Basic Section 48030:Pharmacology-related / Neurochemistry/Neuropharmacology / General physiology / Neurochemistry/Neuropharmacology Except Principal Investigator General physiology
Keywords	Principal Investigator ゼブラフィッシュ / 非天然アミノ酸 / イオンチャネル / タンパク質の立体構造変化 / アセチルコリン受容体 / 立体構造変化 / 遺伝コード拡張法 / イノシトールリン脂質 / 膜電位 / 筋 … More / 電位依存性ナトリウムチャネル / 興奮収縮連関 / 筋収縮 / 活動電位 / 電位依存性ナトリムチャネル / Nav / タンパク質の立体構造 / 阻害剤 / 筋弛緩剤 / キメラタンパク質 / パンクロニウム / 筋弛緩薬 / 膜融合 / 神経筋接合部 / シナプス前終末 / 遺伝コード拡張 / シナプトタグミン / シナプス / 脱リン酸化酵素 / 電位依存性ホスファターゼ / 蛋白質 / 生体分子 / 生理学 / ホスファターゼ / 電位センサー … More Except Principal Investigator 生体膜 / リン脂質 / 蛋白質モジュール / 不飽和脂肪酸 / ホスファターゼ / イノシトールリン脂質 / 電位センサー / 膜電位 / 酵素 / イオンチャネル Less

心筋の電位依存性ナトリウムチャネルを欠失したゼブラフィッシュの解析Principal Investigator
- Principal Investigator
  
  坂田宗平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Physiological implications of the action potential in the zebrafish fast trunk muscle.Principal Investigator
- Principal Investigator
  
  坂田宗平
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Structural study of nitotinic acetylcholine receptors using the genetic code expasionPrincipal Investigator
- Principal Investigator
  
  Sakata Souhei
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Conformation change of synaptotagmin probed by the fluorescent unnatural amino acid in vivoPrincipal Investigator
- Principal Investigator
  
  Sakata Souhei
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka Medical College
Molecular mechanism of the substrate selectivity in Voltage-sensing phosphatasePrincipal Investigator
- Principal Investigator
  
  SAKATA Souhei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Osaka Medical College
  Osaka University
Domain-to-domain coupling in voltage sensor domain proteins
- Principal Investigator
  
  Okamura Yasushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  Osaka University
The study of the coupling mechanisms between the voltage sensor and the enzymatic activity of voltage-sensing phosphatase, VSPPrincipal Investigator
- Principal Investigator
  
  SAKATA Souhei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University

[Book] 生理学用語ハンドブック2024
- Author(s)
  坂田宗平、他多数
- Total Pages
  324
- Publisher
  丸善出版
- ISBN
  9784621309087
- Data Source
  KAKENHI-PROJECT-22K06837
[Book] 脳科学辞典（電子書籍）　分担執筆「電位依存性ナトリウムチャネル」2012
- Author(s)
  坂田宗平、岡村康司
- Publisher
  脳科学辞典編集委員会
- Data Source
  KAKENHI-PROJECT-23700446
[Book] 坂田宗平、岡村康司「電位依存性ナトリウムチャネル」脳科学辞典
- Author(s)
  坂田宗平、岡村康司
- Publisher
  理化学研究所
- Data Source
  KAKENHI-PROJECT-23700446
[Journal Article] Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium2023
- Author(s)
  Sakata Souhei、Ono Fumihito
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 10 Pages: e0292262-e0292262
- DOI
  10.1371/journal.pone.0292262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06837
[Journal Article] Receptor subunit compositions underly distinct potencies of a muscle relaxant in fast and slow muscle fibers2022
- Author(s)
  Manami Yamashita, Yoshihiro Egashira, Shuntaro Nakamura, Souhei Sakata, Fumihito Ono
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 13 Pages: 1026646-1026646
- DOI
  10.3389/fphys.2022.1026646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06429, KAKENHI-PROJECT-22K06837, KAKENHI-PROJECT-21K15348, KAKENHI-PROJECT-19K07334
[Journal Article] Dynamic structural rearrangements and functional regulation of voltage‐sensing phosphatase2019
- Author(s)
  Sakata S and Okamura Y
- Journal Title
  
  Journal of Physiology
  
  Volume: 597 Issue: 1 Pages: 29-40
- DOI
  10.1113/jp274113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07072, KAKENHI-PROJECT-18K19428, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-16K14555, KAKENHI-PLANNED-15H05901, KAKENHI-PROJECT-16H02617
[Journal Article] Polarized PtdIns(4,5)P2distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility2019
- Author(s)
  Kawai Takafumi、Miyata Haruhiko、Nakanishi Hiroki、Sakata Souhei、Morioka Shin、Sasaki Junko、Watanabe Masahiko、Sakimura Kenji、Fujimoto Toyoshi、Sasaki Takehiko、Ikawa Masahito、Okamura Yasushi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 51 Pages: 26020-26028
- DOI
  10.1073/pnas.1916867116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07194, KAKENHI-PROJECT-19K07334, KAKENHI-PROJECT-18K19428, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-18H04877, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-16K07072, KAKENHI-PLANNED-15H05901, KAKENHI-PROJECT-16H02617, KAKENHI-PLANNED-15H05902, KAKENHI-PROJECT-19H03401, KAKENHI-PROJECT-19K22508, KAKENHI-PLANNED-15H05899
[Journal Article] Recent advances in neuromuscular junction research prompted by the zebrafish model2018
- Author(s)
  Egashira Y, Zempo B, Sakata S and Ono F
- Journal Title
  
  Current Opinion in Physiology
  
  Volume: 4 Pages: 70-75
- DOI
  10.1016/j.cophys.2018.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07072
[Journal Article] The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase2018
- Author(s)
  Kawanabe A, Hashimoto M, Mishizawa M, Nishizawa N, Narita H, Yonezawa T, Jinno Y, Sakata S, Nakawaga A and Okamura Y
- Journal Title
  
  eLIFE
  
  Volume: 7 Pages: 2097-2131
- DOI
  10.7554/elife.41653
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07072, KAKENHI-PROJECT-18K19428, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-16K14555, KAKENHI-PLANNED-15H05901, KAKENHI-PROJECT-16H02617
[Journal Article] Domain-to-domain coupling in voltage-sensing phosphatase2017
- Author(s)
  Sakata S, Matsuda M, Kawanabe A, Okamura Y.
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 14 Issue: 0 Pages: 85-97
- DOI
  10.2142/biophysico.14.0_85
- NAID
  130007041363
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07072, KAKENHI-PROJECT-16K14555, KAKENHI-PROJECT-16H02617, KAKENHI-ORGANIZER-15H05897
[Journal Article] Comparison between mouse and sea urchin orthologs of voltage-gated proton channel suggests role of S3 segment in activation gating2016
- Author(s)
  Sakata S, Miyawaki N, McCormack TJ, Arima H, Kawanabe A, Ozkucur N, Kurokawa T, Jinno Y, Fujiwara Y, Okamura Y
- Journal Title
  
  Biochem. Biophys. Acta.
  
  Volume: 1858 Issue: 12 Pages: 2972-2983
- DOI
  10.1016/j.bbamem.2016.09.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253016, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05901, KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-15K18516, KAKENHI-PROJECT-16K07072, KAKENHI-PROJECT-16K08494, KAKENHI-PROJECT-16K14555, KAKENHI-PROJECT-16K15180, KAKENHI-PROJECT-16H02617
[Journal Article] Voltage-dependent motion of the catalytic region of voltage-sensing phosphatase monitored by a fluorescent amino acid2016
- Author(s)
  Sakata S, Jinno Y, Kawanabe A, Okamura Y
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 113 Issue: 27 Pages: 7521-7526
- DOI
  10.1073/pnas.1604218113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253016, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05901, KAKENHI-PROJECT-16K07072, KAKENHI-PROJECT-16K14555, KAKENHI-PROJECT-16H02617
[Journal Article] Gating mechanisms of voltage-gated proton channels.2015
- Author(s)
  Okamura Y, Fujiwara Y, Sakata S.
- Journal Title
  
  Annu Rev Biochem.
  
  Volume: 84 Issue: 1 Pages: 685-709
- DOI
  10.1146/annurev-biochem-060614-034307
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25136713, KAKENHI-PUBLICLY-26111712, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-25670108, KAKENHI-PROJECT-26670102, KAKENHI-PROJECT-25860163, KAKENHI-PROJECT-26291030, KAKENHI-PLANNED-15H05901
[Journal Article] X-ray crystal structure of voltage-gated proton channel2014
- Author(s)
  Takeshita K, Sakata S, Yamashita E, Fujiwara Y, Kawanabe A, Kurokawa T, Okochi Y, Matsuda M, Narita H, Okamura Y & Nakagawa A
- Journal Title
  
  Nat. Strucl. & Mol. Biol.
  
  Volume: (4) Issue: 4 Pages: 352-7
- DOI
  10.1038/nsmb.2783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21229003, KAKENHI-PROJECT-23659111, KAKENHI-PUBLICLY-24111529, KAKENHI-PROJECT-24590277, KAKENHI-PROJECT-24689012, KAKENHI-PROJECT-24890091, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-25670108, KAKENHI-PROJECT-25860163, KAKENHI-PUBLICLY-25136713, KAKENHI-PROJECT-26291030
[Journal Article] Functional diversity of voltage-sensing phosphatases (VSPs) in two urodele amphibians2014
- Author(s)
  Mutua J, Jinno Y, Sakata S, Okochi Y, Ueno S, Tsutsui H, Kawai T, Iwao Y, Okamura Y.
- Journal Title
  
  Physiological Reports
  
  Volume: 2 Issue: 7 Pages: 1-13
- DOI
  10.14814/phy2.12061
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590277, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-25860163, KAKENHI-PROJECT-26670102, KAKENHI-PROJECT-26670103
[Journal Article] Phosphatase activity of the voltage-sensing phosphatase, VSP, shows graded dependence on the extent of activation of the voltage sensor2014
- Author(s)
  Sakata S & Okamura Y
- Journal Title
  
  J. Physiol.
  
  Volume: 592(Pt 5) Issue: 5 Pages: 899-914
- DOI
  10.1113/jphysiol.2013.263640
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21229003, KAKENHI-PUBLICLY-24111529, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-25860163
[Journal Article] A Kir3.4 mutation causes Andersen–Tawil syndrome by an inhibitory effect on Kir2.1.2014
- Author(s)
  Kokunai Y, Nakata T, Furuta M, Sakata S, Kimura H, Aiba T, Yoshinaga M, Osaki Y, Nakamori M, Itoh H, Sato T, Kubota T, Kadota K, Shindo K, Mochizuki H, Shimizu W, Horie M, Okamura Y, Ohno K, Takahashi MP
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 12 Pages: 1058-64
- DOI
  10.1212/wnl.0000000000000239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591245, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24591086, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-25460406, KAKENHI-PROJECT-25860163, KAKENHI-PROJECT-25713034
[Journal Article] 3' Phosphatase activity toward phosphatidylinositol 3,4-bisphosphate [PI(3,4)P2] by voltage-sensing phosphatase (VSP).2012
- Author(s)
  Kurokawa T, Takasuga S, Sakata S, Yamaguchi S, Horie S, Hommma, KJ, Sasaki T and Okamura Y
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 19 Pages: 10089-10094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700446
[Journal Article] Crystal structure of the cytoplasmicphosphatase and tensin homolog (PTEN)-like region of Ciona intestinalis voltage-sensing phosphatase provides insight into substrate specificity and redox regulation of the phosphoinositide phosphatase activity2011
- Author(s)
  Matsuda M, Takeshita K, Kurokawa T, Sakata S, Suzuki M, Yamashita E, Okamura Y and Nakagawa A
- Journal Title
  
  J.Biol.Chem
  
  Volume: 286 Pages: 23368-23377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700446
[Journal Article] Coupling of the phosphatase activity of Ci-VSP to its voltage sensor activity over the entire range of voltage sensitivity.2011
- Author(s)
  Sakata S., Hossain MI., and Okamura Y.
- Journal Title
  
  J.Physiol.
  
  Volume: 589 Pages: 2687-2705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700446
[Journal Article] Coupling of the phosphatase activity of Ci-VSP to its voltage sensor activity over the entire range of voltage sensitivity2011
- Author(s)
  Sakata S., Hossain MI., and Okamura Y.
- Journal Title
  
  J. Physiol.
  
  Volume: 589 Pages: 2687-2705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700446
[Journal Article] Crystal structure of the cytoplasmic phosphatase and tensin homolog (PTEN)-like region of Ciona intestinalis voltage-sensing phosphatase provides insight into substrate specificity and redox regulation of the phosphoinositide phosphatase activity2011
- Author(s)
  Matsuda M., Takeshita K., Kurokawa T., Sakata S., Suzuki M., Yamashita E., Okamura Y., and Nakagawa A.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 23368-23377
- NAID
  120006770867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] 筋の電位依存性ナトリムチャネルをノックアウトしたゼブラフィッシュの運動機能の解析2024
- Author(s)
  坂田宗平、小野富三人
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06837
[Presentation] 電位依存性ナトリウムチャネルをノックアウトしたゼブラフィッシュの解析2023
- Author(s)
  秋山（寺井）千史、小野富三人、坂田宗平
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06837
[Presentation] 電位依存性ナトリウムチャネルをノックアウトしたゼブラフィッシュの解析2023
- Author(s)
  秋山（寺井）千史、小野富三人、坂田宗平
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] 筋弛緩剤パンクロニウムは筋肉型アセチルコリン受容体に対してアロステリックモジュレーターとして働く2022
- Author(s)
  坂田宗平、小野富三人
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] 筋型電位依存性ナトリウムチャネル（Nav1.4）をノックアウトしたゼブラフィッシュの解析2022
- Author(s)
  坂田宗平、秋山（寺井）千史、小野富三人
- Organizer
  第114回近畿生理談話会
- Data Source
  KAKENHI-PROJECT-22K06837
[Presentation] Muscle contraction without the action potential in zebrafish larva2022
- Author(s)
  Sakata S, Terai-Akiyama C, Ono F
- Organizer
  The 39th Congress of International Union of Physiological Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06837
[Presentation] Muscle contraction without the action potential in zebrafish larva2022
- Author(s)
  Terai-Akiyama C, Ono F, Sakata S
- Organizer
  The 39th Congress of International Union of Physiological Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] 筋肉型電位依存性ナトリウムチャネルをノックアウトしたゼブラフィッシュの筋収縮の解析2022
- Author(s)
  寺井千史、小野富三人、坂田宗平
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] 筋型電位依存性ナトリウムチャネル(Nav1.4)をノックアウトしたゼブラフィッシュの解析2022
- Author(s)
  坂田宗平、秋山（寺井）千史、小野富三人
- Organizer
  第114回近畿生理談話会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] Nav1.4ノックアウトゼブラフィッシュの解析2021
- Author(s)
  坂田宗平、寺井千史、小野富三人
- Organizer
  第113回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] The actions of nondepolarizing neuromuscular blocking agents at zebrafish muscle nicotinic acetylcholine receptor isoforms2021
- Author(s)
  Sakata S, Ono F
- Organizer
  第９８回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] Analysis of scn4aa and scn4ab double-knock out zebrafish2021
- Author(s)
  Terai C, Ono F, Sakata S
- Organizer
  第９８回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] Generation and analysis of scn4aa and scn4ab double knock-out zebrafish2020
- Author(s)
  Terai C, Ono F, Sakata S
- Organizer
  第９７回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] ゼブラフィッシュの速筋および遅筋における網羅的な遺伝子発現解析2020
- Author(s)
  坂田宗平、小野富三人
- Organizer
  第９７回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K07072
[Presentation] ゼブラフィッシュの速筋および遅筋における網羅的な遺伝子発現解析2020
- Author(s)
  坂田宗平、小野富三人
- Organizer
  第９７回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] Transcriptome on zebrafish fast- and slow-twitch fiber2020
- Author(s)
  Sakata S, Ono F
- Organizer
  第９７回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07334
[Presentation] Analysis of junctophilin2 knock out zebrafish2019
- Author(s)
  Sakata S and Ono F
- Organizer
  9th FAOPS Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07072
[Presentation] ゼブラフィッシュにおけるジャンクトフィリンの発現と機能の研究2018
- Author(s)
  坂田宗平、小野富三人
- Organizer
  第９５回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K07072
[Presentation] 電位依存性ホスファターゼにおける膜相互作用の動態と役割2017
- Author(s)
  岡村康司、川鍋陽、西澤和久、中川敦史、成田宏隆、坂田宗平、神野有香
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  静岡県浜松市
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性ホスファターゼVSPの新規膜相互作用部位の重要性2017
- Author(s)
  川鍋陽、橋本真宜、米澤智子、神野有香、坂田宗平、岡村康司
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  静岡県浜松市
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 膜脂質と相互作用する可能性のある相同領域による電位依存性ホスファターゼVSPとPTENの機能制御2016
- Author(s)
  川鍋陽、神野有香、坂田宗平、岡村康司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] The role of membrane interacting region of phosphatase domain in voltage-sensing phosohatase (VSP)2016
- Author(s)
  Akira Kawanabe, Masaki Hashimoto, Tomoko Yonezawa, Yuka Jinno, Souhei Sakata, Yasushi Okamura
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  茨城県つくば市
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] ゼブラフィッシュの神経筋接合部を用いたシナプスホメオスタシスの分子メカニズムの研究2016
- Author(s)
  Souhei Sakata , Meghan Mott, Victor Mari Luna, Kimberly Epley and Fumihito Ono
- Organizer
  第９３回日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25860163
[Presentation] 非天然アミノ酸Anapで検出された電位センサーの動き2016
- Author(s)
  筒井秀和、神野有香、坂田宗平、岡村康司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] マウス精子における電位依存性ホスファターゼの機能2016
- Author(s)
  河合喬文、宮田治彦、中西広樹、坂田宗平、有馬大貴、宮脇奈那、大河内善史、渡辺雅彦、崎村建司、佐々木雄彦、伊川正人、岡村康司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] The common regulation of phosphatase activity of voltage-sensing phostophase (VSP) and PTEN by conserved putatiｖe membrane interacting region2016
- Author(s)
  Akira Kawanabe, Tomoko Yonezawa, Yuka Jinno, Souhei Sakata, Yasushi Okamura
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] How does voltage sensor domain regulate downstream effecter?: lesson from voltage-sensor domain proteins2016
- Author(s)
  Yasushi Okamura, Souhei Sakata, Akira Kawanabe, Yuichiro Fujiwara, Yuka Jinno
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  神奈川県横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] Crossroad of electricity and lipid signaling: voltage-sensing phosphoinositide phosphatase (VSP)2016
- Author(s)
  Yasushi Okamura, Akira Kawanabe, Souhei Sakata
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 膜脂質と相互作用する可能性のある騒動領域による電位依存性ホスファターゼVSPとPTENの機能制御2016
- Author(s)
  川鍋　陽、神野有香、坂田宗平、岡村康司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 蛍光を持つ非天然アミノ酸を利用した電位依存性ホスファターゼの酵素ドメインの電位依存的な構造変化の検出2015
- Author(s)
  坂田宗平、岡村康司
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-25860163
[Presentation] 電位依存性ホスファターゼVSPの構造基盤の解明2015
- Author(s)
  岡村康司、川鍋陽、坂田宗平、筒井秀和、中川敦史、成田宏隆、鷹野優、神取秀樹
- Organizer
  ライフサイエンスの革新を目指した構造生命科学と先端的基盤技術　研究領域 CREST 領域会議
- Place of Presentation
  東京都文京区
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性ホスファターゼVSPの構造基盤の解明2015
- Author(s)
  岡村康司、川鍋陽、坂田宗平、筒井秀和、中川敦史、成田宏隆、鷹野優、神取秀樹
- Organizer
  ライフサイエンスの革新を目指した構造生命科学と先端的基盤技術
- Place of Presentation
  東京都文京区
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性ホスファターゼVSPの動作原理とその応用2014
- Author(s)
  岡村康司、坂田宗平、筒井秀和
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2014-03-31
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] Chimeric study between sea urchin and mouse orthologs of voltage-gated proton channel revealed the critical sites for the activation speed2014
- Author(s)
  Souhei Sakata, Nana Miyawaki, Tatsuki Kurokawa, Nurdan Oezkucur, Yasushi Okamura
- Organizer
  第９１回日本生理学会大会
- Place of Presentation
  鹿児島大学　郡元キャンパス
- Data Source
  KAKENHI-PROJECT-25860163
[Presentation] Coupling mechanism between the voltage sensor and the phosphatase domain　in voltage-sensing phosphatase, VSP.2013
- Author(s)
  Sakata S. and Okamura Y.
- Organizer
  1st Awaji Internatioanal Workshop on Electron Spin Science & Technology
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2013-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性ホスファターゼVSPの酵素活性は電位センサーの動いた大きさに応じて段階的に発揮される2013
- Author(s)
  坂田宗平、岡村康司
- Organizer
  日本生理学会
- Place of Presentation
  東京、船堀タワーホール
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] Graded tuning of phosphatase activity of VSP coupled with the intermediate state of the voltage sensor.2013
- Author(s)
  Souhei Sakata and Yasushi Okamura
- Organizer
  57th Annual Meeting of Biophysical Society
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2013-02-04
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] 電位依存性ホスファターゼ VSP の酵素活性は電位センサーの動いた大きさに応じて段階的に発揮される。2013
- Author(s)
  坂田宗平、岡村康司
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京、船堀
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] 電位依存性ホスファターゼVSPの酵素活性は、電位センサーの活性化レベルに応じて段階的に発揮される2013
- Author(s)
  坂田宗平、岡村康司
- Organizer
  第106回近畿生理学談話会
- Place of Presentation
  奈良県橿原市
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性ホスファターゼの動作原理と分子ツールへの応用2013
- Author(s)
  岡村康司、筒井秀和、坂田宗平
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2013-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性ホスファターゼ(VSP)の電位センサーの変異体における電位依存性酵素活性の計測2013
- Author(s)
  坂田宗平、Md.Israil Hossain, 岡村康司
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野、松本
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] 電位依存性ホスファターゼ噓倀の酵素活性は、電位センサーの活性化レベルに応じて段階的に発揮される2013
- Author(s)
  坂田宗平、岡村康司
- Organizer
  第106回近畿生理学談話会
- Place of Presentation
  奈良県立医科大学
- Data Source
  KAKENHI-PROJECT-25860163
[Presentation] Graded tuning of phosphatase activity of VSP coupled with the intermediate state of the voltage sensor2013
- Author(s)
  Souhei Sakata, Yasushi Okamura
- Organizer
  Biophysical society
- Place of Presentation
  アメリカ合衆国、フィラデルフィア、ペンシルバニアコンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] 電位依存性ホスファターゼ(VSP)の電位センサーの変異体における電位依存性酵素活性の計測2012
- Author(s)
  坂田宗平、Md.Israil Hossain, 岡村康司
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] PI(4,5)P2 の可視化と数理モデルの適用による電位依存性ホスファターゼ Ci-VSP の酵素活性の計測2011
- Author(s)
  坂田宗平、岡村康司
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  神奈川、横浜
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-23700446
[Presentation] 蛍光を持つ非天然アミノ酸を利用した電位依存性ホスファターゼの酵素ドメインの電位依存的な構造変化の検出
- Author(s)
  坂田宗平，岡村康司
- Organizer
  第92回日本生理学会大会／第120回解剖学会総会・全国学術集会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 活性化速度の異なるウニおよびマウスVSOP/Hv1の比較による電依依存的ゲート機構
- Author(s)
  坂田　宗平、宮脇　奈那、黒川　竜紀、オズカー　ヌルダン、岡村　康司
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島県鹿児島市
- Year and Date
  2014-03-16 – 2014-03-18
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位センサー蛋白機能の多様性：イオン透過からホスファターゼまで
- Author(s)
  岡村康司、藤原祐一郎、坂田宗平、河合喬文、筒井秀和、大河内善史
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都府京都市
- Year and Date
  2013-06-20 – 2013-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性プロトンチャネルVSOP1/H1の動作原理
- Author(s)
  岡村康司　藤原祐一郎　川鍋陽　坂田宗平　黒川竜紀
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島県鹿児島市
- Year and Date
  2014-03-16 – 2014-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] マウス精子における電位依存性ホスファターゼの機能
- Author(s)
  河合喬文、宮田治彦、中西広樹、坂田宗平、有馬大貴、宮脇奈那、大河内善史、崎村建司、佐々木雄彦、伊川正人、岡村康司
- Organizer
  第92回日本生理学会大会／第120回解剖学会総会・全国学術集会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25253016
[Presentation] 電位依存性プロトンチャネルの結晶構造
- Author(s)
  竹下浩平、坂田宗平、山下栄樹、藤原祐一郎、岡村康司、中川敦史
- Organizer
  第92回日本生理学会大会／第120回解剖学会総会・全国学術集会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25253016
[]

1. Okamura Yasushi (80201987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 中川敦史 (20188890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 藤原祐一郎 (20532980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 筒井秀和 (30392038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. EGASHIRA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. NAKANISHI Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. TAKAHASHI Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 大河内善史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 岡村孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 27 results

Sakata Souhei 坂田 宗平

SAKATA Souhei 坂田 宗平

Research Projects

Research Products

Co-Researchers

心筋の電位依存性ナトリウムチャネルを欠失したゼブラフィッシュの解析Principal Investigator

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Physiological implications of the action potential in the zebrafish fast trunk muscle.Principal Investigator

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Structural study of nitotinic acetylcholine receptors using the genetic code expasionPrincipal Investigator

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Conformation change of synaptotagmin probed by the fluorescent unnatural amino acid in vivoPrincipal Investigator

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Molecular mechanism of the substrate selectivity in Voltage-sensing phosphatasePrincipal Investigator

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Domain-to-domain coupling in voltage sensor domain proteins

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The study of the coupling mechanisms between the voltage sensor and the enzymatic activity of voltage-sensing phosphatase, VSPPrincipal Investigator

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[Book] 生理学用語ハンドブック2024

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[Book] 脳科学辞典（電子書籍） 分担執筆「電位依存性ナトリウムチャネル」2012

Author(s)

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[Book] 坂田宗平、岡村康司「電位依存性ナトリウムチャネル」脳科学辞典

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[Journal Article] Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium2023

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[Journal Article] Receptor subunit compositions underly distinct potencies of a muscle relaxant in fast and slow muscle fibers2022

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[Journal Article] Dynamic structural rearrangements and functional regulation of voltage‐sensing phosphatase2019

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[Journal Article] Polarized PtdIns(4,5)P2distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility2019

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DOI

Sakata Souhei 坂田宗平

SAKATA Souhei 坂田宗平

[Book] 脳科学辞典（電子書籍）　分担執筆「電位依存性ナトリウムチャネル」2012