KAKITA HIROKI 垣田博樹

… Alternative Names

Kakita Hiroki 垣田博樹

KAKITA Hiroki 垣田博樹

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Researcher Number	40528949
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 愛知医科大学, 医学部, 准教授 2016 – 2022: 愛知医科大学, 医学部, 講師 2015: 愛知医科大学, 医学部, 助教 2013: 名古屋市立大学, 大学院医学研究科, 研究員 2012 – 2013: 名古屋市立大学, 医学(系)研究科(研究院), 研究員 2011 – 2012: 名古屋市立大学, 医学(系)研究科(研究院), 助教 2010 – 2011: 名古屋市立大学, 大学院・医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Embryonic/Neonatal medicine Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Embryonic/Neonatal medicine
Keywords	Principal Investigator アストロサイト / ミクログリア / エリスロポエチン / 低体温療法 / グリア / 新生児低酸素性虚血性脳症 / 新生児脳障害 / 低酸素性虚血性脳症 / 一酸化窒素 / 神経炎症 … More / 脳室周囲白質軟化症 / 新生児仮死 / ニューロン / 脳低温療法 / サイトカイン / アクアポリン / 血液脳関門 / ジクロフェナック / グリア細胞 / インフルエンザ脳症 … More Except Principal Investigator ミクログリア / グリア / 早産児 / サイトカイン / Neuroprotection / SGA infant / Neotatology / 早産時 / 新生児脳障害 / 副腎不全 / 脳室周囲白質軟化症 / 晩期循環不全 / 炎症性細胞 / エリスロポエチン / 微小環境 / 脳内炎症 / 低体温療法 / 新生児低酸素性虚血性脳症 / 新生児 / 発達障害 / 疼痛 / 痛み / 自閉症スペクトラム障害 / ASD / development / infant / NICU / HPA axis / ASDs / neonate / pain / 神経科学 / 低酸素 / iNOS / MYRF / ミエリン / オリゴデンドロサイト / インフルエンザ脳症 / 血液・脳関門 / 血管内皮細胞 / アストロサイト / グリア細胞 / 急性脳症 / 血液脳関門 Less

低体温療法を応用したグリアの機能制御による新生児脳室周囲白質軟化症の新規治療法Principal Investigator
- Principal Investigator
  
  垣田博樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
SGA児の大脳皮質構造異常とトロンボポエチンによる神経予後改善を目指した治療戦略
- Principal Investigator
  
  竹下覚
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
Comprehensive Novel Treatment Strategy for Neonatal Brain Injury via Glial Function Modulation with a Focus on Hypothermia TherapyPrincipal Investigator
- Principal Investigator
  
  Kakita Hiroki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
new therapy for neonatal hypoxic ischemic encephalopathy by the crosstalk between inflammatory cells and glial cells
- Principal Investigator
  
  Aoyama Mineyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya City University
Elucidation of the pathogenesis of adrenal insufficiency and periventricular leukomalacia with a focus on gliosis, and establishment of novel preventive measures
- Principal Investigator
  
  Ueda Hiroko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
New hypothermia therapy by the glial microenvironment for the neonatal hypoxic ischemic encephalopathyPrincipal Investigator
- Principal Investigator
  
  Hiroki Kakita
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
Elucidation of the pathogenesis of acute encephalitis/encephalopathy with a focus on glia
- Principal Investigator
  
  Kurahashi Hirokazu
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University
Development of endocrinological method to prevent future ASDs induced by neonatal pain
- Principal Investigator
  
  YAMADA YASUMASA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Aichi Medical University
Hypothermia attenuate brain damage by coordinating the function of gliaPrincipal Investigator
- Principal Investigator
  
  Kakita Hiroki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Aichi Medical University
インフルエンザ脳症発症時にグリア細胞の機能異常が脳障害増悪に及ぼす影響Principal Investigator
- Principal Investigator
  
  垣田博樹
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya City University
Analysis of boold-brain barrier breakdown in the early stage of acute encephalopathy
- Principal Investigator
  
  ASAI Kiyofumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya City University
Diclofenac enhances proinflammatory cytokine-induced phagocytosis through nitric oxide production in cultured microgliaPrincipal Investigator
- Principal Investigator
  
  KAKITA Hiroki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya City University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Thrombopoietin exerts a neuroprotective effect by inhibiting the suppression of neuronal proliferation and axonal outgrowth in intrauterine growth restriction rats2024
- Author(s)
  Takeshita Satoru、Kakita Hiroki、Nakamura Nami、Mori Mari、Toriuchi Kohki、Aoki Hiromasa、Inoue Yasumichi、Hayashi Hidetoshi、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Experimental Neurology
  
  Volume: 377 Pages: 114781-114781
- DOI
  10.1016/j.expneurol.2024.114781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14984, KAKENHI-PROJECT-23K15455, KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21H02650
[Journal Article] Monocyte-Derived miRNA-1914-5p Attenuates IL-1β?Induced Monocyte Adhesion and Transmigration2023
- Author(s)
  Toriuchi Kohki、Kihara Toshie、Aoki Hiromasa、Kakita Hiroki、Takeshita Satoru、Ueda Hiroko、Inoue Yasumichi、Hayashi Hidetoshi、Shimono Yohei、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 3 Pages: 2829-2829
- DOI
  10.3390/ijms24032829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21H02650, KAKENHI-PROJECT-20K07052, KAKENHI-PROJECT-20K16939, KAKENHI-PROJECT-21K16403, KAKENHI-PROJECT-23K21387
[Journal Article] Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV42023
- Author(s)
  Fukuda Naoya、Toriuchi Kohki、Mimoto Rina、Aoki Hiromasa、Kakita Hiroki、Suzuki Yoshiaki、Takeshita Satoru、Tamura Tetsuya、Yamamura Hisao、Inoue Yasumichi、Hayashi Hidetoshi、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Neurochemical Research
  
  Volume: 49 Issue: 3 Pages: 800-813
- DOI
  10.1007/s11064-023-04075-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14984, KAKENHI-PROJECT-23K15455, KAKENHI-PROJECT-22K09168, KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21K07830, KAKENHI-PROJECT-21H02650, KAKENHI-PROJECT-23K24049
[Journal Article] The DNMT3B Inhibitor Nanaomycin A as a Neuroblastoma TherapeuticAgent2023
- Author(s)
  Izumi Kazuya、Aoki Hiromasa、Kakita Hiroki、Takeshita Satoru、Ueda Hiroko、Inoue Yasumichi、Hayashi Hidetoshi、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Current Cancer Drug Targets
  
  Volume: 23 Issue: 11 Pages: 837-842
- DOI
  10.2174/1568009623666230522113645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15455, KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21H02650
[Journal Article] Efficacy of tolvaptan in an infant with syndrome of inappropriate antidiuretic hormone secretion associated with holoprosencephaly: A case report2023
- Author(s)
  Mori Mari、Takeshita Satoru、Nakamura Nami、Mizuno Yuki、Tomita Akiko、Aoyama Mineyoshi、Kakita Hiroki、Yamada Yasumasa
- Journal Title
  
  World Journal of Clinical Cases
  
  Volume: 11 Issue: 26 Pages: 6262-6267
- DOI
  10.12998/wjcc.v11.i26.6262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08211
[Journal Article] Successful Noninvasive Respiratory Management of an Infant with Bilateral Choanal Atresia and a Supernumerary Nostril Located on the Columella by a Mouthpiece: A Case Report2023
- Author(s)
  Nakamura Nami、Kakita Hiroki、Takagi Mizuki、Asai Shimpei、Asai Takafumi、Mori Mari、Takeshita Satoru、Ueda Hiroko、Aoyama Mineyoshi、Kishimoto Mayuko、Ito Kunihiro、Yamada Yasumasa
- Journal Title
  
  American Journal of Case Reports
  
  Volume: 24
- DOI
  10.12659/ajcr.939642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08211
[Journal Article] AMPK activators suppress cholesterol accumulation in macrophages via suppression of the mTOR pathway2023
- Author(s)
  Owaki Reina、Aoki Hiromasa、Toriuchi Kohki、Inoue Yasumichi、Hayashi Hidetoshi、Takeshita Satoru、Kakita Hiroki、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Experimental Cell Research
  
  Volume: 432 Issue: 1 Pages: 113784-113784
- DOI
  10.1016/j.yexcr.2023.113784
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14984, KAKENHI-PROJECT-23K15455, KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21K07830, KAKENHI-PROJECT-21H02650
[Journal Article] Thrombocytopenia and insufficient thrombopoietin production in human small-for-gestational-age infants2022
- Author(s)
  Takeshita Satoru、Kakita Hiroki、Asai Shimpei、Asai Takafumi、Mori Mari、Ueda Hiroko、Aoki Hiromasa、Aoyama Mineyoshi、Yamada Yasumasa
- Journal Title
  
  Pediatric Research
  
  Volume: 93 Issue: 3 Pages: 619-624
- DOI
  10.1038/s41390-022-02107-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-20K16939, KAKENHI-PROJECT-21K16403
[Journal Article] The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes2022
- Author(s)
  Joyo Yuji、Kawaguchi Yohei、Yonezu Hiroki、Senda Hiroya、Yasuma Sanshiro、Shiraga Hiroo、Nozaki Masahiro、Aoyama Mineyoshi、Asai Kiyofumi、Murakami Hideki、Waguri-Nagaya Yuko
- Journal Title
  
  Immunologic Research
  
  Volume: 70 Issue: 2 Pages: 208-215
- DOI
  10.1007/s12026-022-09261-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-20K09465, KAKENHI-PROJECT-19K18473
[Journal Article] Hyperglycemia and Lactic Acidosis Associated with Linezolid Therapy in an Extremely Premature Infant2022
- Author(s)
  Asai Takafumi、Kakita Hiroki、Nakamura Nami、Asai Shimpei、Mori Mari、Takeshita Satoru、Ueda Hiroko、Mizuno Yuki、Tomita Akiko、Aoyama Mineyoshi、Yamada Yasumasa
- Journal Title
  
  Neonatology
  
  Volume: 119 Issue: 6 Pages: 781-784
- DOI
  10.1159/000526702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08211
[Journal Article] Interleukin-1β enhances cell adhesion in human endothelial cells via microRNA-1914?5p suppression2021
- Author(s)
  Kihara Toshie、Toriuchi Kohki、Aoki Hiromasa、Kakita Hiroki、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 27 Pages: 101046-101046
- DOI
  10.1016/j.bbrep.2021.101046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22715, KAKENHI-PROJECT-21J13766, KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21K16403
[Journal Article] Hypothermia Attenuates Neuronal Damage via Inhibition of Microglial Activation, Including Suppression of Microglial Cytokine Production and Phagocytosis2021
- Author(s)
  Kimura Tomoka、Toriuchi Kohki、Kakita Hiroki、Tamura Tetsuya、Takeshita Satoru、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Cellular and Molecular Neurobiology
  
  Volume: 41 Issue: 3 Pages: 459-468
- DOI
  10.1007/s10571-020-00860-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-19K18362, KAKENHI-PROJECT-20K16939, KAKENHI-PROJECT-18K07832, KAKENHI-PROJECT-17K10086, KAKENHI-PROJECT-21K07830
[Journal Article] Insufficient thrombopoietin due to hepatic dysmature results in thrombocytopenia in small‐for‐gestational‐age rats2021
- Author(s)
  Takeshita Satoru、Kakita Hiroki、Toriuchi Kohki、Aoki Hiromasa、Ueda Hiroko、Wakatsuki Akihiko、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  British Journal of Haematology
  
  Volume: 192 Issue: 4
- DOI
  10.1111/bjh.17294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-20K16939
[Journal Article] Prolonged astrocyte-derived erythropoietin expression attenuates neuronal damage under hypothermic conditions2020
- Author(s)
  Kohki Toriuchi,1 Hiroki Kakita,1,2 Tetsuya Tamura,3 Satoru Takeshita,1,2 Yasumasa Yamada,2 and Mineyoshi Aoyamacorresponding author1
- Journal Title
  
  J Neuroinflammation.
  
  Volume: 17 Issue: 1 Pages: 141-141
- DOI
  10.1186/s12974-020-01831-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08443, KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-19K18362, KAKENHI-PROJECT-20K16939, KAKENHI-PROJECT-18K07832
[Journal Article] IL-6 promotes cell adhesion in human endothelial cells via microRNA-126?3p suppression2020
- Author(s)
  Ohta Momoka、Kihara Toshie、Toriuchi Kohki、Aoki Hiromasa、Iwaki Soichiro、Kakita Hiroki、Yamada Yasumasa、Aoyama Mineyoshi
- Journal Title
  
  Experimental Cell Research
  
  Volume: 393 Issue: 2 Pages: 112094-112094
- DOI
  10.1016/j.yexcr.2020.112094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-18K07832
[Journal Article] Corticotrophin-releasing hormone stimulation tests in late-onset circulatory collapse.2019
- Author(s)
  Ueda H, Kakita H, Ichimura S, Mori M, Takeshita S, Goto T, Kondo T, Yamada Y.
- Journal Title
  
  Pediatr Int.
  
  Volume: 61(11) Issue: 11 Pages: 1114-1119
- DOI
  10.1111/ped.13956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10197
[Journal Article] 新生児低酸素性虚血性脳症の治療　低体温療法を中心に(総説)2019
- Author(s)
  垣田博樹
- Journal Title
  
  東海産科婦人科学会雑誌
  
  Volume: 55 Pages: 9-16
- Data Source
  KAKENHI-PROJECT-18K07832
[Journal Article] 新生児低酸素性虚血性脳症の治療　;低体温療法を中心に2018
- Author(s)
  垣田博樹
- Journal Title
  
  東海産科婦人科学会誌
  
  Volume: 55 Pages: 9-16
- Data Source
  KAKENHI-PROJECT-18K07832
[Journal Article] Case report of Pierre Robin sequence with severe upper airway obstruction who was rescued by fiberoptic nasotracheal intubation.2017
- Author(s)
  Satoru Takeshita, Hiroko Ueda, Tatenobu Goto, Hiroki Kakita, Kazuo Oshima, Takahisa Tainaka, Takayuki Ono, Yoshiaki Kazaoka, Yasumasa Yamada
- Journal Title
  
  BMC anesthesiology
  
  Volume: 17 Issue: 1 Pages: 43-43
- DOI
  10.1186/s12871-017-0336-0
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19697, KAKENHI-PROJECT-15K09718
[Journal Article] Neuroprotective erythropoietin attenuates microglial activation, including morphological changes, phagocytosis, and cytokine production.2017
- Author(s)
  Tamura T, Aoyama M, Ukai S, Kakita H, Sobue K, Asai K
- Journal Title
  
  Brain Res
  
  Volume: 1662 Pages: 65-74
- DOI
  10.1016/j.brainres.2017.02.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10101, KAKENHI-PROJECT-16K10946, KAKENHI-PROJECT-16K10913, KAKENHI-PROJECT-17K11020, KAKENHI-PROJECT-15K09718
[Journal Article] CXCR4+CD45- cells are niche forming for osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 signaling pathways in bone marrow.2016
- Author(s)
  Goto Y, Aoyama M, Sekiya T, Waguri-Nagaya Y, Miyazawa K, Asai K, Goto S.
- Journal Title
  
  Stem Cells
  
  Volume: 34 Issue: 11 Pages: 2733-2743
- DOI
  10.1002/stem.2440
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462309, KAKENHI-PROJECT-15K09718, KAKENHI-PROJECT-16K10101, KAKENHI-PROJECT-16K10913
[Journal Article] Fatal Tension Pneumopericardium in an Extremely Low Birth Weight Infant to Identify the Perforation Site of the Pericardium2016
- Author(s)
  Daisuke Muto, Hiroki Kakita, Satoru Takeshita, Hiroko Ueda, Tatenobu Goto and Yasumasa Yamada
- Journal Title
  
  Pediatrics & Therapeutics
  
  Volume: 6 Issue: 01 Pages: 277-277
- DOI
  10.4172/2161-0665.1000277
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09718
[Journal Article] Neonatal Central Diabetes Insipidus Caused by Severe Perinatal Asphyxia2016
- Author(s)
  Hiroko Ueda, Shingo Numoto, Hiroki Kakita, Satoru Takeshita, Daisuke Muto, Tatenobu Goto, Haruo Mizuno, Akihisa Okumura and Yasumasa Yamada
- Journal Title
  
  Pediatrics & Therapeutics
  
  Volume: 6 Issue: 01 Pages: 278-278
- DOI
  10.4172/2161-0665.1000278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09718
[Journal Article] 高インスリン血性低血糖を合併した13トリソミーの症例2016
- Author(s)
  佐藤新紀子, 垣田博樹, 今峰浩貴
- Journal Title
  
  日本新生児成育医学会雑誌
  
  Volume: 28 Pages: 65-69
- NAID
  40021166206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09718
[Journal Article] Diclofenac enhances proinflammatory cytokine-induced aquaporin-4 expression in cultured astrocyte2013
- Author(s)
  Asai H, Kakita H, Aoyama M, Nagaya Y, Saitoh S, Asai K.
- Journal Title
  
  Cell Mol Neurobiol.
  
  Volume: 33 Issue: 3 Pages: 393-400
- DOI
  10.1007/s10571-013-9905-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591165, KAKENHI-PROJECT-22591713, KAKENHI-PROJECT-22791448, KAKENHI-PROJECT-23591509
[Journal Article] Diclofenac enhances proinflammatory cytokine-induced phagocytosis of cultured microglia via nitric oxide production.2013
- Author(s)
  Kakita H, Aoyama M, Nagaya Y, Asai H, Hussein MH, Suzuki M, Kato S, Saitoh S, Asai K.
- Journal Title
  
  Toxicol Appl Pharmacol.
  
  Volume: 268 Issue: 2 Pages: 99-105
- DOI
  10.1016/j.taap.2013.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591165, KAKENHI-PROJECT-23591509
[Journal Article] Hypothermia attenuates the severity of oxidative stress development in asphyxiated newborns2012
- Author(s)
  Kakita H, et al
- Journal Title
  
  J Crit Care
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790993
[Journal Article] Region-specific expression of a water channel protein, aquaporin 4, on brain astrocytes.2012
- Author(s)
  Aoyama M, Kakita H, Kato S, Tomita M, Asai K.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 90 Issue: 12 Pages: 2272-80
- DOI
  10.1002/jnr.23117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591165, KAKENHI-PROJECT-23591509
[Journal Article] Endogenous erythropoietin from astrocyte protects the oligodendrocyte precursor cell against hypoxic and reoxygenation injury2011
- Author(s)
  Kato S, Aoyama M, Hida, H, et al. 11名4番目
- Journal Title
  
  J Neurosci. Res.
  
  Volume: 89 Issue: 10 Pages: 1566-74
- DOI
  10.1002/jnr.22702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591419, KAKENHI-PROJECT-22591165, KAKENHI-PROJECT-22790993, KAKENHI-PROJECT-23591509
[Journal Article] Atypical social development in NICU survivors at 12 months2011
- Author(s)
  Yamda Y, Kakita H, et al
- Journal Title
  
  Pediatr Int
  
  Volume: 53 Pages: 858-866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790993
[Journal Article] Endogenous erythropoietin from astrocyte protects the oligodendrocyte precursor cell against hypoxic and reoxygenation injury2011
- Author(s)
  Kato S, Kakita H, et al
- Journal Title
  
  J Neurosci Res
  
  Volume: 89 Pages: 1566-1574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790993
[Journal Article] Atypical social development in NICU survivors at 12 months
- Author(s)
  Yamada Y, Yoshida F, Hemmi H, Ito M, Kakita H, Yoshikawa T, Hishida M, Iguchi T, Seo T, Nakanishi K
- Journal Title
  
  Pediatr Int
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790993
[Presentation] TRPV4-AMPK-NF-κB経路抑制を介する低温刺激によってミクログリアの過剰な炎症反応は鎮静化する2023
- Author(s)
  三本里奈、鳥内皐暉、福田直哉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] Potential therapeutic agent nanaomycin A as a DNMT3B inhibitor in neuroblastoma.2023
- Author(s)
  泉和弥、青木啓将、垣田博樹、竹下覚、上田博子、井上靖道、林秀敏、山田恭聖、青山峰芳
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] miR-1914-5p regulates vascular endothelial cell-monocyte adhesion in the inflammatory environment of atherosclerosis2023
- Author(s)
  鳥内皐暉、木原星衣、青木啓将、竹下覚、垣田博樹、山田恭聖、青山峰芳
- Organizer
  第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温状態はTRPV4を介してミクログリアの活性を抑制し神経保護効果を発揮する2023
- Author(s)
  垣田博樹
- Organizer
  第67回日本成育新生児学会
- Data Source
  KAKENHI-PROJECT-21K07830
[Presentation] 低温刺激はTRPV4を介してミクログリアの神経傷害的な活性化を抑制する2023
- Author(s)
  三本里奈、鳥内皐暉、福田直哉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] Hypothermia attenuates neurotoxic microglial activation via TRPV4 channel2023
- Author(s)
  鳥内皐暉、福田直哉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  第66回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] Neuroprotective mechanisms of hypothermia by maintaining astrocytic erythropoietin production2023
- Author(s)
  鳥内皐暉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  Neuroscience 2023
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] Hypothermic culture enhances secretion of astrocyte-derived neuroprotective erythropoietin.2022
- Author(s)
  鳥内皐暉, 垣田博樹, 青木啓将, 田村哲也, 竹下覚, 山田恭聖, 青山峰芳
- Organizer
  先端モデル動物支援プラットフォーム若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温状態はミクログリアの炎症性サイトカイン、iNOS発現および貪食能抑制することで神経保護効果を発揮する2022
- Author(s)
  垣田博樹
- Organizer
  日本新生児成育医学会
- Data Source
  KAKENHI-PROJECT-21K07830
[Presentation] 低温培養はアストロサイトにおけるエリスロポエチン発現を持続させニューロンのアポトーシスを抑制する2021
- Author(s)
  鳥内皐暉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温培養はLPSによるミクログリアの神経傷害的な活性化を抑制する2021
- Author(s)
  福田直哉、木村友香、鳥内皐暉、青木啓将、垣田博樹、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温培養によるアストロサイトのエリスロポエチン分泌亢進を介した神経保護効果2021
- Author(s)
  鳥内皐暉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  医療薬学フォーラム2021
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] Neuroprotective effect of hypothermia by maintaining erythropoietin expression in astrocytes2021
- Author(s)
  鳥内皐暉、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 細胞周期チェックポイント阻害剤併用による抗腫瘍効果2020
- Author(s)
  戸崎友梨、青木啓将、久保田英嗣、垣田博樹、山田恭聖、片岡洋望、青山峰芳
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部　合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温培養はミクログリアの過剰な炎症反応を鎮静し神経保護効果をもたらす2020
- Author(s)
  鳥内皐暉、木村友香、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  第138回　日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] miR-1914-5pは血管内皮細胞の単球接着性を変化させ動脈硬化の病変形成に関与する2020
- Author(s)
  木原星衣、鳥内皐暉、青木啓将、垣田博樹、山田恭聖、青山峰芳
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部　合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温培養はミクログリアの活性化を制御し神経細胞死を抑制する2020
- Author(s)
  鳥内皐暉、木村友香、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  第67回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温培養はミクログリアの神経傷害的な活性化を抑制し神経保護効果をもたらす2020
- Author(s)
  鳥内皐暉、木村友香、垣田博樹、青木啓将、田村哲也、竹下覚、山田恭聖、青山峰芳
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部　合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K08211
[Presentation] 低温状態においてアストロサイトが分泌するエリスロポエチンを介した神経保護効果2019
- Author(s)
  垣田博樹
- Organizer
  第64回日本新生児成育医学会　学術集会
- Data Source
  KAKENHI-PROJECT-18K07832
[Presentation] エリスロポエチンのミクログリア活性抑制による神経保護作用2017
- Author(s)
  垣田博樹、竹下覚、上田博子、近藤知子、山田恭聖
- Organizer
  第５３回　日本周産期新生児学会
- Data Source
  KAKENHI-PROJECT-15K09718
[Presentation] 炎症性サイトカインTNFαによるアストロサイトから分泌される神経保護因子エリスロポエチンの産生抑制メカニズムの解明2016
- Author(s)
  垣田博樹、長屋嘉顕、竹下覚、上田博子、後藤盾信、武藤大輔、山田恭聖
- Organizer
  第６１回日本新生児成育医学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K09718
[Presentation] ジクロフェナックナトリウムがサイトカイン存在下でのミクログリア貪食能に及ぼす影響－インフルエンザ感染に伴う脳症悪化のメカニズムの解明－2013
- Author(s)
  青山峰芳、垣田博樹、長屋嘉顕、鈴木美恵子、浅井清文
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] ジクロフェナックナトリウムがサイトカイン存在下でのミクログリア貪食能に及ぼす影響−インフルエンザ感染に伴う脳症悪化のメカニズムの解明−2013
- Author(s)
  青山峰芳、垣田博樹、長屋嘉顕、鈴木美恵子、浅井清文
- Organizer
  Neuro2013,第56回日本神経化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] アストロサイト由来エリスロポエチンによるオリゴデンドロサイト前駆細胞への細胞障害抑制効果2013
- Author(s)
  青山峰芳、加藤晋、垣田博樹、飛田秀樹、浅井清文
- Organizer
  第60回中部日本生理学会
- Place of Presentation
  岐阜大学(岐阜)
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] ジクロフェナックがミクログリアのiNOS/NOx産生と活性化に及ぼす影響について2012
- Author(s)
  垣田博樹、青山峰芳、加藤　晋、浅井隼人、長屋嘉顕、齋藤伸治、浅井清文
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] Diclofenac enhances aquaporin4 expression in cultured astrocyte with proinflammatory cytokine treatment.2012
- Author(s)
  Asai H, Kakita H, Aoyama M, Nagaya Y, Asai K
- Organizer
  The 11st Biennial Meeting of the Asian-Pacific Society for Neurochemistry
- Place of Presentation
  Kobe International Conference Center (Kobe)
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] アストロサイト由来エリスロポエチンのオリゴデンドロサイト前駆細胞への細胞障害抑制効果2012
- Author(s)
  青山峰芳、加藤　晋、垣田博樹、浅井隼人、長屋嘉顕、浅井清文
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] アストロサイト由来エリスロポエチンのオリゴデンドロサイト前駆細胞への細胞障害抑制効果2012
- Author(s)
  青山峰芳、加藤晋、垣田博樹、浅井隼人、長屋嘉顕、浅井清文
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] ジクロフェナックがミクログリアのiNOS/NOx産生と活性化に及ぼす影響について2012
- Author(s)
  垣田博樹、青山峰芳、加藤晋、浅井隼人、長屋嘉顕、齋藤伸治、浅井清文
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] 脳内部位により異なるアストロサイトでのアクアポリン4の発現2012
- Author(s)
  青山峰芳、冨田愛美、浅井清文、垣田博樹、加藤晋、浅井隼人、長屋嘉顕
- Organizer
  第17回グリア研究会
- Place of Presentation
  神戸
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] 脳内部位により異なるアストロサイトでのアクアポリン４の発現2012
- Author(s)
  青山峰芳、冨田愛美、浅井清文、垣田博樹、加藤　晋、浅井隼人、長屋嘉顕
- Organizer
  第17回グリア研究会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] Diclofenac enhances aquaporin4 expression in cultured astrocyte with proinflammatory cytokine treatment2012
- Author(s)
  Asai H, Kakita H, Aoyama M, Nagaya Y, Asai K .
- Organizer
  The 11st Biennial Meeting of the Asian-Pacific Society for Neurochemistry,55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] 内在性エリスロポエチンのオリゴデンドロサイト前駆細胞への細胞保護効果2011
- Author(s)
  青山峰芳、加藤晋、垣田博樹、浅井隼人、長屋嘉顕、浅井清文
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] アストロサイト由来エリスロポエチンがオリゴデンドロサイト前駆細胞に与える影響2011
- Author(s)
  垣田博樹, 他
- Organizer
  第47回日本周産期新生児学会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-22790993
[Presentation] アストロサイト由来エリスロポエチンがオリゴデンドロサイト前駆細胞に与える影響2011
- Author(s)
  垣田博樹
- Organizer
  第47回日本周産期・新生児学会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-22790993
[Presentation] ジクロフェナックナトリウムがミクログリアの貪食能に及ぼす影響−インフルエンザ感染に伴う脳症悪化のメカニズム−2011
- Author(s)
  青山峰芳、垣田博樹、長屋嘉顕、浅井隼人、鈴木美恵子、浅井清文
- Organizer
  第16回グリア研究会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23591509
[Presentation] ジクロフェナックによるNFκBシグナルを介したアストロサイトでのNOx産生増強2010
- Author(s)
  垣田博樹
- Organizer
  第113回日本小児科学会
- Place of Presentation
  盛岡(市民文化ホール)
- Data Source
  KAKENHI-PROJECT-22790993
[Presentation] 脳低温療法が酸化ストレスマーカーに及ぼす影響についての検討2010
- Author(s)
  垣田博樹
- Organizer
  第55回日本未熟児新生児学会
- Place of Presentation
  神戸(国際会議場)
- Data Source
  KAKENHI-PROJECT-22790993

1. AOYAMA Mineyoshi (70363918)

# of Collaborated Projects: 8 results

# of Collaborated Products: 43 results
2. YAMADA YASUMASA (60405165)

# of Collaborated Projects: 6 results

# of Collaborated Products: 25 results
3. ASAI Kiyofumi (70212462)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
4. 竹下覚 (20715875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Kurahashi Hirokazu (30621817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Ueda Hiroko (60528959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 奥村彰久 (60303624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 青木啓将 (70881845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 鳥内皐暉 (70965946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 和栗祐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 飛田秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAKITA HIROKI 垣田 博樹

Kakita Hiroki 垣田 博樹

KAKITA Hiroki 垣田 博樹

Research Projects

Research Products

Co-Researchers

低体温療法を応用したグリアの機能制御による新生児脳室周囲白質軟化症の新規治療法Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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SGA児の大脳皮質構造異常とトロンボポエチンによる神経予後改善を目指した治療戦略

Principal Investigator

Project Period (FY)

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Review Section

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Comprehensive Novel Treatment Strategy for Neonatal Brain Injury via Glial Function Modulation with a Focus on Hypothermia TherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

new therapy for neonatal hypoxic ischemic encephalopathy by the crosstalk between inflammatory cells and glial cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of adrenal insufficiency and periventricular leukomalacia with a focus on gliosis, and establishment of novel preventive measures

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New hypothermia therapy by the glial microenvironment for the neonatal hypoxic ischemic encephalopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Elucidation of the pathogenesis of acute encephalitis/encephalopathy with a focus on glia

Principal Investigator

Project Period (FY)

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Research Institution

Development of endocrinological method to prevent future ASDs induced by neonatal pain

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Hypothermia attenuate brain damage by coordinating the function of gliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

インフルエンザ脳症発症時にグリア細胞の機能異常が脳障害増悪に及ぼす影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of boold-brain barrier breakdown in the early stage of acute encephalopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Diclofenac enhances proinflammatory cytokine-induced phagocytosis through nitric oxide production in cultured microgliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Thrombopoietin exerts a neuroprotective effect by inhibiting the suppression of neuronal proliferation and axonal outgrowth in intrauterine growth restriction rats2024

Author(s)

KAKITA HIROKI 垣田博樹

Kakita Hiroki 垣田博樹

KAKITA Hiroki 垣田博樹