iwamoto hideki 岩本英希

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Iwamoto Hideki 岩本英希

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Researcher Number	40529541
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2015 – 2024: 久留米大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Gastroenterology
Keywords	Principal Investigator 血管新生 / 肝細胞癌 / 癌血管内皮細胞 / マイクロRNA / 癌血管 / ＡＭＰＫ / 耐性 / 低酸素誘導因子 / エネルギー代謝 / 血管新生阻害剤 / AMPK / 血管新生抑制治療 … More Except Principal Investigator … More 肝細胞癌 / 免疫回避機構 / 非古典的Wntシグナル経路 / Wnt5a / Germ free / サイトカイン / ケモカイン / リンパ球 / 血管新生阻害剤 / 腫瘍免疫 / シンバイオティックス / 血管新生抑制 / 抗腫瘍効果 / 免疫チェックポイント阻害剤 / 腸内細菌叢 / バイオマーカー / CpG island / CpGアイランド / DNAメチル化 / 肝発がん / 非癌部肝組織 / DNAメチル化異常 / 多中心性再発 Less

Elucidation of Wnt5a-mediated immune evasion mechanisms in hepatocellular carcinoma and their application to combined immunotherapy
- Principal Investigator
  
  古賀浩徳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
The investigation of factors influencing on therapeutic effect of anti-PD-1 antibody therapy for hepatocellular carcinoma by comprehensive analysis of intestinal flora
- Principal Investigator
  
  Torimura Takuji
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kurume University
Establishment of a novel anti-angiogenic treatment targeting Tumor endothelial cell specific non-coding RNAPrincipal Investigator
- Principal Investigator
  
  Hideki Iwamoto
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
DNA methylation level of 10 CpG sites on 8 specific genes in non-cancerous liver tissues is useful to predict multicentric recurrence of hepatocellular carcinoma after surgical resection
- Principal Investigator
  
  Torimura Takuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
The possiblity of resistance for anti-angiogenic therapy and therapeutic biomarker in tumor AMP-activated protein kinasePrincipal Investigator
- Principal Investigator
  
  Iwamoto Hideki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] ラムシルマブによる肝細胞癌治療2020
- Author(s)
  鳥村拓司、中野聖士、岩本英希
- Total Pages
  223
- Publisher
  アークメディア
- ISBN
  9784875832379
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Anti-PD-L1 antibodies promote cellular proliferation by activating the PD-L1-AXL signal relay in liver cancer cells2023
- Author(s)
  Tanaka T, Koga H, Suzuki H, Iwamoto H, Sakaue T, Masuda A, Nakamura T, Akiba J, Yano H, Torimura T, Kawaguchi T.
- Journal Title
  
  Hepatol Int.
  
  Volume: 8 Issue: 3 Pages: 984-997
- DOI
  10.1007/s12072-023-10572-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Tumor-derived insulin-like growth factor-binding protein-1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors. Cancer Communications.2023
- Author(s)
  Suzuki H, Iwamoto H, Seki T, Nakamura T, Masuda A, Sakaue T, Tanaka T, Imamura Y, Niizeki T, Nakano M, Shimose S, Shirono T, Noda Y, Kamachi N, Sakai M, Morita K, Nakayama M, Yoshizumi T, Kuromatsu R, Yano H, Cao Y, Koga H, Torimura T.
- Journal Title
  
  Cancer Communications.
  
  Volume: 43 Issue: 4 Pages: 415-434
- DOI
  10.1002/cac2.12411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Kurume Med J.2023
- Author(s)
  Goto Y, Niizeki T, Fukutomi S, Shirono T, Shimose S, Iwamoto H, Kojima S, Kanno H, Uchino Y, Sasaki S, Shirahama N, Muroya D, Nomura Y, Akashi M, Nakayama G, Hirakawa Y, Sato T, Yoshitomi M, Sakai H, Hisaka T, Kakuma T, Koga H, Torimura T, Akagi Y, Okuda K.
- Journal Title
  
  Kurume Med J.
  
  Volume: 68 Pages: 239-245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] The Beneficial Impact of MAFLD on Lenvatinib Treatment in Patients with Non-viral Hepatocellular Carcinoma.2023
- Author(s)
  Shimose S, Hiraoka A, Casadei-Gardini A, Tsutsumi T, Nakano D, Iwamoto H, Tada F, Rimini M, Tanaka M, Torimura T, Suga H, Ohama H, Burgio V, Niizeki T, Moriyama E, Suzuki H, Shirono T, Noda Y, Kamachi N, Nakano M, Kuromatsu R, Koga H, Kawaguchi T.
- Journal Title
  
  Hepatology Research.
  
  Volume: 53 Issue: 2 Pages: 104-115
- DOI
  10.1111/hepr.13843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Efficacy of Lenvatinib Combined with Transcatheter Intra-Arterial Therapies for Patients with Advanced-Stage of Hepatocellular Carcinoma: A Propensity Score Matching.2023
- Author(s)
  Shimose S, Iwamoto H, Niizeki T, Tanaka M, Shirono T, Moriyama E, Noda Y, Nakano M, Suga H, Kuromatsu R, Torimura T, Koga H, Kawaguchi T.
- Journal Title
  
  International journal of molecular sciences.
  
  Volume: 24 Issue: 18 Pages: 13715-13715
- DOI
  10.3390/ijms241813715
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Durable complete response is achieved by balloon-occluded transcatheter arterial chemoembolization for hepatocellular carcinoma.2022
- Author(s)
  Shirono T, Iwamoto H, Niizeki T, Shimose S, Kajiwara A, Suzuki H, Kamachi N, Noda Y, Okamura S, Nakano M, Kuromatsu R, Murotani K, Koga H, Torimura T.
- Journal Title
  
  Hepatology Communications.
  
  Volume: 6 Issue: 9 Pages: 2594-2604
- DOI
  10.1002/hep4.2016
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] The Clinical Impact of Hepatic Arterial Infusion Chemotherapy New-FP for Hepatocellular Carcinoma with Preserved Liver Function.2022
- Author(s)
  Iwamoto H, Niizeki T, Nagamatsu H, Ueshima K, Tani J, Kuzuya T, Kasai K, Kooka Y, Hiraoka A, Sugimoto R, Yonezawa T, Tanaka S, Deguchi A, Shimose S, Shirono T, Sakai M, Suzuki H, Moriyama E, Koga H, Torimura T, Kawaguchi T, New Fp Study Group, Kurume Liver Cancer Study Group of Japan.
- Journal Title
  
  Cancers.
  
  Volume: 14 Issue: 19 Pages: 4873-4873
- DOI
  10.3390/cancers14194873
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Deterioration of liver function and aging disturb sequential systemic therapy for unresectable hepatocellular carcinoma.2022
- Author(s)
  Shimose S, Hiraoka A, Tanaka M, Iwamoto H, Tanaka T, Noguchi K, Aino H, Yamaguchi T, Itano S, Suga H, Niizeki T, Moriyama E, Shirono T, Noda Y, Kamachi N, Okamura S, Nakano M, Kawaguchi T, Kuromatsu R, Koga H, Torimura T.
- Journal Title
  
  Scientific Reports.
  
  Volume: 12 Issue: 1 Pages: 17018-17018
- DOI
  10.1038/s41598-022-21528-2
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Immunological inflammatory biomarkers as prognostic predictors for advanced hepatocellular carcinoma2021
- Author(s)
  Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H, Torimura T, Kurume Liver Cancer Study Group of Japan
- Journal Title
  
  ESMO Open
  
  Volume: 6 Issue: 1 Pages: 100020-100020
- DOI
  10.1016/j.esmoop.2020.100020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Alternating Lenvatinib and Trans-Arterial Therapy Prolongs Overall Survival in Patients with Inter-Mediate Stage HepatoCellular Carcinoma: A Propensity Score Matching Study2021
- Author(s)
  Shimose S, Iwamoto H, Tanaka M, Niizeki T, Shirono T, Noda Y, Kamachi N, Okamura S, Nakano M, Suga H, Yamaguchi T, Kawaguchi T, Kuromatsu R, Noguchi K, Koga H, Torimura T
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 1 Pages: 160-160
- DOI
  10.3390/cancers13010160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Initial Experience of Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma in Real-World Clinical Practice2021
- Author(s)
  Iwamoto H, Shimose S, Noda Y, Shirono T, Niizeki T, Nakano M, Okamura S, Kamachi N, Suzuki H, Sakai M, Kajiwara A, Itano S, Tanaka M, Yamaguchi T, Kuromatsu R, Koga H, Torimura T andon behalf of The Kurume Liver Cancer Study Group of Japan
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 11 Pages: 2786-2786
- DOI
  10.3390/cancers13112786
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] "First-line sorafenib sequential therapy and liver disease etiology for unresectable hepatocellular carcinoma using inverse probability weighting: A multicenter retrospective study "2021
- Author(s)
  Shimose S, Hiraoka A, Nakano M, Iwamoto H, Tanaka M, Tanaka T, Noguchi K, Aino H, Ogata K, Kajiwara M, Itano S, Yokokura Y, Yamaguchi T, Kawano H, Matsukuma N, Suga H, Niizeki T, Shirono T, Noda Y, Kamachi N, Okamura S, Kawaguchi T, Koga H, Torimura T
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 23 Pages: 8530-8541
- DOI
  10.1002/cam4.4367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Survival Benefit of Hepatic Arterial Infusion Chemotherapy over Sorafenib in the Treatment of Locally Progressed Hepatocellular Carcinoma2021
- Author(s)
  Iwamoto H, Niizeki T, Nagamatsu H, Shimose S, Shirono T, Nakano M, Okamura S, Noda Y, Kamachi N, Sakai M, Suzuki H, Kuromatsu R, Kawaguchi A, Koga H, Torimura T,et al.
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 4 Pages: 646-646
- DOI
  10.3390/cancers13040646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Clinical Importance of Regimens in Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma with Macrovascular Invasion2021
- Author(s)
  Niizeki T, Iwamoto H, Shirono T, Shimose S, Nakano M, Okamura S, Noda Y, Kamachi N, Hiroyuki S, Sakai M, Kuromatsu R, Koga H and Torimura T
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 17 Pages: 4550-4550
- DOI
  10.3390/cancers13174450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Indication of Suitable Transarterial Chemoembolization and Multikinase Inhibitors for Intermediate Stage Hepatocellular Carcinoma2020
- Author(s)
  Shimose S, Kawaguchi T, Iwamoto H, Niizeki T, Shirono T, Tanaka M, Koga H, Torimura T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 19 Pages: 2667-2676
- DOI
  10.3892/ol.2020.11399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Primary Treatment with Molecular-Targeted Agents for Hepatocellular Carcinoma: A Propensity Score-matching Analysis.2020
- Author(s)
  14Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H, Torimura T.
- Journal Title
  
  Hepatology Communications.
  
  Volume: 4 Issue: 8 Pages: 1218-1228
- DOI
  10.1002/hep4.1535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Controlling Nutritional Status (CONUT) Score Is Associated With Overall Survival in Patients With Unresectable Hepatocellular Carcinoma Treated With Lenvatinib: A Multicenter Cohort Study2020
- Author(s)
  Shimose S, Kawaguchi T, Iwamoto H, Tanaka M, Miyazaki K, Ono M, Niizeki T, Shirono T, Okamura S, Nakano M, Suga H, Yamaguchi T, Yokokura Y, Noguchi K, Koga H, Torimura T.
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 4 Pages: 1076-1089
- DOI
  10.3390/nu12041076
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Weekends-Off Lenvatinib for Unresectable Hepatocellular Carcinoma Improves Therapeutic Response and Tolerability Toward Adverse Events2020
- Author(s)
  Iwamoto Hideki、Suzuki Hiroyuki、Shimose Shigeo、Niizeki Takashi、Nakano Masahito、Shirono Tomotake、Okamura Shusuke、Noda Yu、Kamachi Naoki、Nakamura Toru、Masuda Atsutaka、Sakaue Takahiko、Tanaka Toshimitsu、Nakano Dan、Sakai Miwa、Yamaguchi Taizo、Kuromatsu Ryoko、Koga Hironori、Torimura Takuji
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 4 Pages: 1010-1010
- DOI
  10.3390/cancers12041010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Prognostic Impact of Transcatheter Arterial Chemoembolization (TACE) Combined With Radiofrequency Ablation in Patients With Unresectable Hepatocellular Carcinoma: Comparison With TACE Alone Using Decision-Tree Analysis After Propensity Score Matching2019
- Author(s)
  Shimose S, Tanaka M, Iwamoto H, Niizeki T, Shirono T, Aino H, Noda Y, Kamachi N, Okamura S, Nakano M, Kuromatsu R, Kawaguchi T, Kawaguchi A, Koga H, Yokokura Y, Torimura T.
- Journal Title
  
  Hepatol Res.
  
  Volume: 49 Issue: 8 Pages: 919-928
- DOI
  10.1111/hepr.13348
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Effects of in-hospital exercise on liver function, physical ability, and muscle mass during treatment of hepatoma in patients with chronic liver disease.2017
- Author(s)
  Koya S, Kawaguchi T, Hashida R, Goto E, Matsuse H, Saito H, Hirota K, Taira R, Matsushita Y, Imanaga M, Nagamatsu A, Shirono T, Shimose S, Iwamoto H, Niizeki T, Kuromatsu R, Miura H, Shiba N, Torimura T.
- Journal Title
  
  Hepatol Res
  
  Volume: 47 Issue: 3
- DOI
  10.1111/hepr.12718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09385
[Journal Article] STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury.2017
- Author(s)
  Abe M, Yoshida T, Akiba J, Ikezono Y, Wada F, Masuda A, Sakaue T, Tanaka T, Iwamoto H, Nakamura T, Sata M, Koga H, Yoshimura A, Torimura T.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 23 Issue: 37 Pages: 6833-6844
- DOI
  10.3748/wjg.v23.i37.6833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09385, KAKENHI-PROJECT-17K08776
[Journal Article] Antiangiogenic and Antitumor Activities of Aflibercept, a Soluble VEGF Receptor-1 and -2, in a Mouse Model of Hepatocellular Carcinoma.2016
- Author(s)
  Torimura T, Iwamoto H, Nakamura T, Abe M, Ikezono Y, Wada F, Sakaue T, Masuda H, Hashimoto O, Koga H, Ueno T, Yano H.
- Journal Title
  
  Neoplasia
  
  Volume: 18 Issue: 7 Pages: 413-424
- DOI
  10.1016/j.neo.2016.05.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-16K09385
[Journal Article] Alternative treatments in advanced hepatocellular carcinoma patients with progressive disease after sorafenib treatment: a prospective multicenter cohort study.2016
- Author(s)
  Nakano M, Tanaka M, Kuromatsu R, Nagamatsu H, Satani M, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Koga H, Torimura T; Kurume Liver Cancer Study Group Of Japan.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 39 Pages: 64400-64409
- DOI
  10.18632/oncotarget.10794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-16K09385
[Journal Article] Diffusion-weighted magnetic resonance imaging predicts malignant potential in small hepatocellular carcinoma2016
- Author(s)
  Okamura S, Sumie S, Tonan T, Nakano M, Satani M, Shimose S, Shirono T, Iwamoto H, Aino H, Niizeki T, Tajiri N, Kuromatsu R, Okuda K, Nakashima O, Torimura TOkamura S, Sumie S, Tonan T, Nakano M, Satani M, Shimose S, Shirono T, Iwamoto H, Aino H, Niizeki T, Tajiri N, Kuromatsu R, Okuda K, Nakashima O, Torimura T
- Journal Title
  
  Dig Liver Dis
  
  Volume: 48 Pages: 945-952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09385
[Journal Article] Antiangiogenic and Antitumor Actitivies of Aflibercept, a soluble VEGF receptor 1 and 2, in a mouse model of hepatocellular carcinoma2016
- Author(s)
  Takuji Torimura, Hideki Iwamoto, Toru Nakamura, Mitsuhiko Abe, Yu Ikezono, Fumitaka Wada, Takahiko　Sakaue, Hiroshi Masuda, Osamu Hashimoto, Hironori Koga, Takato Udeno, Hirohisa Yano
- Journal Title
  
  Neoplasia
  
  Volume: Vol18 No7 Pages: 413-424
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21555
[Journal Article] Inhibition of hypoxia-inducible factor via upregulation of von Hippel-Lindau protein induces "angiogenic switch off" in a hepatoma mouse model2015
- Author(s)
  Hideki Iwamoto et al.
- Journal Title
  
  Molecular Therapy- Oncolytics
  
  Volume: 2 Pages: 15020-15020
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21555
[Presentation] アテゾリズマブ・ベバシズマブ併用療法開始早期の単球増加不良は治療効果不良を予測しうる2022
- Author(s)
  鈴木浩之、岩本英希、下瀬茂男、新関　敬、中野聖士、城野智毅、野田　悠、蒲池直紀、山口泰三、中村　徹、増田篤高、田中俊光、黒松亮子、古賀浩徳、鳥村拓司.
- Organizer
  第58回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝動注化学療法はアテゾリズマブ＋ベバシズマブ併用療法の奏効性を高める2022
- Author(s)
  岩本英希、鳥村拓司
- Organizer
  第58回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 抗PD-L1抗体による肝癌細胞増殖機構の解明.2022
- Author(s)
  田中俊光、古賀浩徳、鈴木浩之、岩本英希、阪上尊彦、増田篤高、中村徹、秋葉　純、矢野博久、鳥村拓司.
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌のレンバチニブ薬剤耐性における癌線維芽細胞の HGF-cMET シグナルの重要性2022
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第108回日本消化器病学会総会.
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Circulating IGFBP-1 provides molecular targeted agent-resistance in hepatocellular carcinoma2021
- Author(s)
  Suzuki H, Iwamoto H, Nakamura T, Masuda A, Sakaue T, Tanaka T, Niizeki T, Okamura S, Shimose S, Shirono T, Noda Y, Kamachi N, Kuromatsu R, Koga H, Torimura T
- Organizer
  JSH International Liver Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌における癌血管特異的micro RNAを利用した新規血管新生抑制治療2021
- Author(s)
  岩本英希
- Organizer
  第５７回肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K15831
[Presentation] BCLC B 肝細胞癌におけるレンバチニブ療法の post-progression survival 及び post treatmentの検討2021
- Author(s)
  下瀬茂男、新関　敬、岩本英希、城野智毅、蒲池直紀、野田　悠、岡村修祐、中野聖士、黒松亮子、古賀浩徳、鳥村拓司
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Novel anti-angiogenic therapy using tumor endothelial cell-specific micro RNA in hepatocellular carcinoma2021
- Author(s)
  Hideki Iwamoto
- Organizer
  JSH Internaltional liver conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15831
[Presentation] 進行肝細胞癌に対するアテゾリズマブ,ベバシズマブ併用療法の安全性と有効性の評価-多施設共同研究-2021
- Author(s)
  下瀬茂男、岩本英希、新関　敬、城野智毅、野田　悠、岡村修祐、古賀浩徳、鳥村拓司
- Organizer
  29th JDDW（第25回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 高齢者進行肝細胞癌に対するアテゾリズマブ及びベバシズマブ併用療法の使用経験2021
- Author(s)
  城野智毅、新関　敬、岩本英希、下瀬茂男、野田　悠、岡村修祐、古賀浩徳、鳥村拓司
- Organizer
  29th JDDW（第25回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] "INITIAL EXPERIENCE OF ATEZOLIZUMAB PLUS BEVACIZUMAB FOR UNRESECTABLE HEPATOCELLULAR CARCINOMA IN REAL-WORLD CLINICAL PRACTICE"2021
- Author(s)
  Iwamoto H, Shimose S, Takashi N, Noda Y, Shirono T, Nakano M, Okamura S, Kamachi N, Suzuki H, Kuromatsu R, Koga H and Torimura T
- Organizer
  The Liver Meeting Digital Experience 2021（The 72th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Primary Treatment with Molecular-targeted Agents for Hepatocellular carcinoma: A Propensity Score-matching Analysis2021
- Author(s)
  Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H, Torimura T
- Organizer
  JSH International Liver Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌に対する肝動注化学療法 New FP 療法とソラフェニブの治療成績の多施設後ろ向き比較研究2021
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] TACE不応肝細胞癌に対するレンバチニブ療法とrepeated TACEの有効性の比較　傾向スコアを用いて.2020
- Author(s)
  下瀬茂男、新関　敬、岩本英希、城野智毅、岡村修祐、中野聖士、高田晃男、田中正俊、古賀浩徳、鳥村拓司.
- Organizer
  28th JDDW（第24回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Lenvatinibは腫瘍微小環境をimmune cold からhotへと変化させる.2020
- Author(s)
  鈴木浩之、岩本英希、鳥村拓司
- Organizer
  28th JDDW（第24回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌に対する血管新生阻害剤の正常臓器血管への影響と癌血管特異的遺伝子の探索2020
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌（HCC）に対するBalloon-Occluded Transarterial Chemoembolization（B-TACE）とCoventional TACE（C-TACE）のTE4.2020
- Author(s)
  城野智毅、新関　敬、岩本英希、下瀬茂男、蒲池直紀、野田　悠、岡村修祐、中野聖士、黒松亮子、古賀浩徳、鳥村拓司.
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 造影CTにおける造影効果を含めた腫瘍因子からみたレンバチニブの治療効果について.2020
- Author(s)
  岡村修祐、下瀬茂男、新関　敬、蒲池直紀、野田　悠、城野智毅、岩本英希、中野聖士、黒松亮子、古賀浩徳、鳥村拓司.
- Organizer
  28th JDDW（第24回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] A Comparative Study of Necrosis-inducing Effect on Hepatocellular Carcinoma: Balloon-Occluded VS. Conventional Transcatheter Arterial2019
- Author(s)
  Shirono T, Iwamoto H, Niizeki T, Shimose S, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Involvement of WNT Signaling in Two-faced Actions of Claudin-2 in Liver Cancer Cells2019
- Author(s)
  Koga H, Imamura Y, Nakamura T, Iwamoto H, Sakaue T, Masuda A, Tanaka T, Nakano D, Suzuki H, Yano H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Real World Evidence of Lenvatinib in Adavanced Hepatocellular Carcinoma: A Multicenter Cohort Study2019
- Author(s)
  Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Lenvatinib Alters Tumor Immune Microenvironment from ‘COLD’ TO ‘HOT’ in Hepatocellular Carcinoma2019
- Author(s)
  Suzuki H, Iwamoto H, Tanaka T, Sakaue T, Masuda A, Nakamura T, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Prognostic Indication of Transarterial Chemoembolization and Multikinase Inhibitors in Patients with Intermediate Stage Hepatocellular Carcinoma2019
- Author(s)
  Shimose S, Kawaguchi T, Iwamoto H, Niizeki T, Shirono T, Tanaka M, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Fatty liver environment confers antiangiogenic drug resistance to hepatocellular carcinoma and metastatic liver cancer of colorectal cancer through activation of lipid dependent metabolic pathway2018
- Author(s)
  岩本英希
- Organizer
  アメリカ肝臓学会年次総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15831
[Presentation] 非癌部肝組織のDNAメチル化の変化は肝細胞癌の多中心性発生のバイオマーカーになり得る2018
- Author(s)
  岩本英希　古賀浩徳　山本健　鳥村拓司
- Organizer
  第42回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] DNA methylation level of 10 CpG sites on 8 specific genes in non-cancerous liver tissues is useful to predict multicentric recurrence of hepatocellular carcinoma after surgical resection2018
- Author(s)
  Takuji Torimura, Hironori Koga, Toru Nakamura, Hideki Iwamoto, Yasuko Imamura, Hiroshi Suzuki, Takahiko Sakaue, Mitsuhiko Abe, Atsutaka Masuda, Toshimitsu Tanaka, Hirohisa Yano, Ken Yamamoto
- Organizer
  AASLD The liver meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] 当院における肉眼的脈管浸潤を伴う進行肝細胞癌に対する肝動注化学療法とsorafenibの比較2017
- Author(s)
  新関　敬, 中野聖士, 岩本英希, 下瀬茂男, 城野智毅, 相野　一, 黒松亮子, 古賀浩徳, 鳥村拓司
- Organizer
  第53回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] C-TACEとDEB-TACEの直接治療効果から、その選択を考察する2017
- Author(s)
  下瀬茂男, 新関　敬, 田中正俊, 城野智毅, 岩本英希, 野田　悠, 岡村修祐, 中野聖士, 佐谷　学, 黒松亮子, 古賀浩徳, 鳥村拓司
- Organizer
  第53回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] Targeting CD44v9-xCT system by sulfasalazine to overcome cisplatin resistance in human liver cancer cells2017
- Author(s)
  Wada F, Koga H, Jun Akiba, Yu Ikezono, Nakamura T, Abe M, Iwamoto H, Sakaue T, Masuda A, Tanaka T, Yano H, Torimura T
- Organizer
  The 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] 血管新生抑制剤の中止は肝類洞のRevascularizationを引き起こす2017
- Author(s)
  岩本英希, 古賀浩徳, 鳥村拓司
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] Inhibition of hypoxia inducible factor via upregulation of von Hippel-Lindau protein induces ‘Angiogenic switch off’ in a mouse hepatoma model2017
- Author(s)
  Iwamoto H,, Koga H, Torimura T
- Organizer
  The 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] ACE不応stage3肝癌症例へのDEB-TACE局所制御の検討2017
- Author(s)
  下瀬茂男, 新関　敬, 城野智毅, 岩本英希, 田中正俊, 古賀浩徳, 鳥村拓司
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] STAT3 deficiency prevents hepatocarcinogenesis and promotes transdifferentiation of hepatocytes into biliary cells in chronic liver injury of mice2017
- Author(s)
  be M, Yoshida T, Akiba J, Ikezono Y, Wada F, Masuda A, Sakaue T, Tanaka T, Iwamoto H, Nakamura T, Sata M, Koga H, Yoshimura A, Torimura T
- Organizer
  The 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] The Wnt Target Gene CLAUDIN-2 Regulates Tumorigenesis of Combined Hepatocellular- Cholangiocarcinoma Cells2017
- Author(s)
  Koga H, Imamura Y, Wada F, Ikezono Y, Abe M,, Iwamoto H, Nakamura T, Sakaue T, Tanaka T, Yano H, Torimura T
- Organizer
  The 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] HES1はWNTシグナル改変肝癌細胞においてスフィア形成能や造腫瘍能を決定的に制御する2017
- Author(s)
  古賀浩徳, 中村　徹, 和田史孝, 岩本英希, 増田篤高, 阪上尊彦, 田中俊光, 安倍満彦, 秋葉　純, 矢野博久, 鳥村拓司
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] DNA methylation level of non-cancerous liver tissue has potential for being a biomarker of multicentric recurrence of hepatocellular carcinoma2016
- Author(s)
  Torimura T, Koga H, Nakamura T, Iwamoto H, Imamura Y, Ikezono Y, Sakaue T, Wada F, Masuda A, Tanaka T, Yano H, Ueno T, Yamamoto K
- Organizer
  The 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Place of Presentation
  Boston, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effect and drug resistance2016
- Author(s)
  岩本英希
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K21555
[Presentation] マウス肝癌モデルを用いたNotch抑制剤の効果検討2016
- Author(s)
  岩本英希、鳥村拓司、古賀浩徳
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオタニ幕張、他　千葉市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] The Wnt effector T-CELL FACTOR-4 isoform activates Notch signaling via upregulating CLAUDIN-2 in human liver cancer cells2016
- Author(s)
  Koga H, Kim M, Imamua Y, Ikezono Y, Wada F, Iwamoto H, Nakamura T, Sakaue T, Masuda A, Tanaka T, Yano H, Wands JR, Torimura T
- Organizer
  The 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Place of Presentation
  Boston, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09385
[Presentation] マウス肝癌モデルを用いたNotch抑制剤の効果検討2016
- Author(s)
  岩本英希
- Organizer
  第５２回肝臓学会総会
- Place of Presentation
  千葉県　千葉市美浜区
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K21555
[Presentation] 腫瘍Transglutaminase2を標的とした新規血管新生阻害剤SQAPの肝細胞癌に対する効果の基礎的検討2015
- Author(s)
  岩本英希
- Organizer
  日本消化器病週間　肝臓大会
- Place of Presentation
  東京都　グランドプリンス新高輪
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K21555
[Presentation] 肝癌における血管新生の重要性2015
- Author(s)
  岩本英希
- Organizer
  日本臨床分子形態学会
- Place of Presentation
  長崎県　長崎大学医学部　ポンぺ会館
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-15K21555

1. Torimura Takuji (60197986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 58 results
2. 古賀浩徳 (90268855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 40 results
3. 中村徹 (30341332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 矢野博久 (40220206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 山本健 (60274528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 光山慶一 (20200066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

iwamoto hideki 岩本 英希

Iwamoto Hideki 岩本 英希

Research Projects

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Co-Researchers

Elucidation of Wnt5a-mediated immune evasion mechanisms in hepatocellular carcinoma and their application to combined immunotherapy

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The investigation of factors influencing on therapeutic effect of anti-PD-1 antibody therapy for hepatocellular carcinoma by comprehensive analysis of intestinal flora

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Establishment of a novel anti-angiogenic treatment targeting Tumor endothelial cell specific non-coding RNAPrincipal Investigator

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DNA methylation level of 10 CpG sites on 8 specific genes in non-cancerous liver tissues is useful to predict multicentric recurrence of hepatocellular carcinoma after surgical resection

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The possiblity of resistance for anti-angiogenic therapy and therapeutic biomarker in tumor AMP-activated protein kinasePrincipal Investigator

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[Book] ラムシルマブによる肝細胞癌治療2020

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[Journal Article] Anti-PD-L1 antibodies promote cellular proliferation by activating the PD-L1-AXL signal relay in liver cancer cells2023

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[Journal Article] Tumor-derived insulin-like growth factor-binding protein-1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors. Cancer Communications.2023

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[Journal Article] Kurume Med J.2023

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[Journal Article] The Beneficial Impact of MAFLD on Lenvatinib Treatment in Patients with Non-viral Hepatocellular Carcinoma.2023

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[Journal Article] Efficacy of Lenvatinib Combined with Transcatheter Intra-Arterial Therapies for Patients with Advanced-Stage of Hepatocellular Carcinoma: A Propensity Score Matching.2023

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[Journal Article] Durable complete response is achieved by balloon-occluded transcatheter arterial chemoembolization for hepatocellular carcinoma.2022

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[Journal Article] The Clinical Impact of Hepatic Arterial Infusion Chemotherapy New-FP for Hepatocellular Carcinoma with Preserved Liver Function.2022

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[Journal Article] Deterioration of liver function and aging disturb sequential systemic therapy for unresectable hepatocellular carcinoma.2022

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iwamoto hideki 岩本英希

Iwamoto Hideki 岩本英希