Nishitsuji Kazuchika 西辻和親

… Alternative Names

NISHITSUJI Kazuchika 西辻和親

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Researcher Number	40532768
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 和歌山県立医科大学, 医学部, 准教授 2020: 和歌山県立医科大学, 医学部, 講師 2018: 和歌山県立医科大学, 医学部, 講師 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2013 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Neurology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Experimental pathology
Keywords	Principal Investigator アミロイドーシス / アミロイド / ヘパラン硫酸 / 妊娠高血圧腎症 / トランスサイレチン / グリコサミノグリカン / 腫瘍微小環境 / 卵巣癌 / p53 / トロホブラスト … More / アルツハイマー病 / Aβ / 栄養膜細胞 / 合胞体性栄養膜細胞 / 細胞性栄養膜細胞 / 絨毛外栄養膜細胞 / シンシチウム化 / 胎盤形成不全 / 胎盤 / アミロイドβ / 硫酸化糖鎖 / 糖鎖 / 細胞外硫酸化糖鎖 / 細胞外糖鎖 … More Except Principal Investigator 小胞体 / マクロファージ / 脂肪滴 / 細胞内脂肪滴 / 子宮頸癌 / アミロイドーシス / 卵巣癌 / p53 / ミトコンドリア / 胎盤 / 泡沫化 / 腫瘍細胞 / 後期エンドゾーム / CD44 / 悪性腫瘍 / コレステロールエステル / コレステロール / ACAT1 / 内膜増殖 / 術後性肺静脈狭窄症 / 血管平滑筋 / 内膜肥厚 / 粥状動脈硬化 / 酸化ストレス / 平滑筋 / ヘムオキシゲナーゼ１ / 腫瘍病理学 Less

Effests of p53 aggregates on tumor microenvironment in p53-mutated ovarian cancerPrincipal Investigator
- Principal Investigator
  
  西辻和親
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
細胞内脂肪滴蓄積を標的とした子宮頸癌の新たな予後予測と治療戦略
- Principal Investigator
  
  西岡香穂
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
妊娠高血圧腎症胎盤における硫酸化糖鎖の病態機能解析Principal Investigator
- Principal Investigator
  
  西辻和親
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
Relationship between mitochondria-ER interaction in placental development
- Principal Investigator
  
  岩橋尚幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
p53アミロイドーシスとしてのp53遺伝子変異卵巣癌の病態メカニズムの解明
- Principal Investigator
  
  池崎みどり
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
Novel mechanism of amyloid beta-induced placentation defectsPrincipal Investigator
- Principal Investigator
  
  Nishitsuji Kazuchika
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Wakayama Medical University
Enzymatic remodeling of heparan sulfate: a therapeutic strategy for systemic amyloidosesPrincipal Investigator
- Principal Investigator
  
  Kazuchika Nishitsuji
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Wakayama Medical University
  The University of Tokushima
ACAT1陽性泡沫化腫瘍細胞のコレステロールエステル要求性の解明と治療法の探索
- Principal Investigator
  
  坂下直実
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokushima
Role of glycosaminoglycans in ATTR amyloidosisPrincipal Investigator
- Principal Investigator
  
  NISHITSUJI Kazuchika
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokushima
Approach to mechanism for post-operative pulmonary vein stenosis: experimental trials for adventitial hemorrhage-associated oxidative stress regulation
- Principal Investigator
  
  SAKASHITA Naomi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokushima
アポトーシス関連M2マクロファージ分化抑制による病態制御－高悪性度腫瘍について
- Principal Investigator
  
  HORIGUCHI Hidehisa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokushima

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium2024
- Author(s)
  Takeda-Uchimura Yoshiko、Ikezaki Midori、Akama Tomoya O.、Ihara Yoshito、Allain Fabrice、Nishitsuji Kazuchika、Uchimura Kenji
- Journal Title
  
  Molecules
  
  Volume: 29 Issue: 4 Pages: 764-764
- DOI
  10.3390/molecules29040764
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09623
[Journal Article] Functions of Protein <i>C</i>-Mannosylation in Physiology and Pathology2023
- Author(s)
  Nishitsuji Kazuchika、Ikezaki Midori、Manabe Shino、Ihara Yoshito
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 35 Issue: 204 Pages: E23-E27
- DOI
  10.4052/tigg.2218.1E
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2023-03-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-22K09623, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605
[Journal Article] Calnexin is involved in forskolim-induced syncytialization in cytotrophoblast model BeWo cells2022
- Author(s)
  Matsukawa H, Ikezaki M, Nishioka K, Iwahashi N, Fujimoto M, Nishitsuji K, Ihara Y, Ino K
- Journal Title
  
  Biomolecules
  
  Volume: 12(8) Issue: 8 Pages: 1050-1050
- DOI
  10.3390/biom12081050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09626, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-21K09500, KAKENHI-PROJECT-22K09623, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605
[Journal Article] Effect of hydrophobic moment on membrane interaction and cell penetration of apolipoprotein E‐derived arginine‐rich amphipathic α‐helical peptides2022
- Author(s)
  Yuki Takechi‐Haraya, Takashi Ohgita, Mana Kotani, Hiroki Kono, Chihiro Saito, Hiroko Tamagaki‐Asahina, Kazuchika Nishitsuji, Kenji Uchimura, Takeshi Sato, Ryuji Kawano, Kumiko Sakai‐Kato, Ken‐ichi Izutsu and Hiroyuki Saito
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 4959-4959
- DOI
  10.1038/s41598-022-08876-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14337, KAKENHI-PROJECT-20K15982, KAKENHI-PROJECT-20K09605
[Journal Article] Investigation of <scp>PRAME</scp> expression in lipid‐laden and non‐lipid‐laden cutaneous histiocytes2022
- Author(s)
  Fujimoto Masakazu、Jinnouchi Keita、Kaku Yo、Hirata Masahiro、Nishitsuji Kazuchika、Haga Hironori
- Journal Title
  
  Journal of Cutaneous Pathology
  
  Volume: 49 Issue: 12 Pages: 1011-1014
- DOI
  10.1111/cup.14334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09605
[Journal Article] Complementary Role of GlcNAc6ST2 and GlcNAc6ST3 in Synthesis of CL40-Reactive Sialylated and Sulfated Glycans in the Mouse Pleural Mesothelium2022
- Author(s)
  Takeda-Uchimura Yoshiko、Ikezaki Midori、Akama Tomoya O.、Nishioka Kaho、Ihara Yoshito、Allain Fabrice、Nishitsuji Kazuchika、Uchimura Kenji
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 14 Pages: 4543-4543
- DOI
  10.3390/molecules27144543
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-22K09623, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605
[Journal Article] Design and Synthesis of 6-O-Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid β Aggregation.2022
- Author(s)
  Uchimura K., Nishitsuji K, Chiu L.-T., Ohgita T., Saito H., Allain F., Gannedi V., Wong C.-H., and Hung S.-C.
- Journal Title
  
  ChemBioChem
  
  Volume: 23 Issue: 15 Pages: 4543-4543
- DOI
  10.1002/cbic.202200191
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06556, KAKENHI-PROJECT-21K15245, KAKENHI-PROJECT-20K09605
[Journal Article] Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis2022
- Author(s)
  Iwahashi N, Ikezaki M, Komohara Y, Fujiwara Y, Noguchi T, Nishioka K, Sakai K, Nishio K, Ueda M, Ihara Y, Uchimura K, Ino K, Nishitsuji K
- Journal Title
  
  PNAS Nexus
  
  Volume: 1(3) Issue: 3
- DOI
  10.1093/pnasnexus/pgac128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09626, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-22K09623, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605
[Journal Article] Beta3Gn-T7 Is a Keratan Sulfate β1,3 N-Acetylglucosaminyltransferase in the Adult Brain2022
- Author(s)
  Takeda-Uchimura Yoshiko、Nishitsuji Kazuchika、Ikezaki Midori、Akama Tomoya O.、Ihara Yoshito、Allain Fabrice、Uchimura Kenji
- Journal Title
  
  Frontiers in Neuroanatomy
  
  Volume: 16 Pages: 813841-813841
- DOI
  10.3389/fnana.2022.813841
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-20K09605
[Journal Article] Extracellular endosulfatase Sulf-2 harbors a chondroitin/dermatan sulfate chain that modulates its enzyme activity2022
- Author(s)
  R. El Masri, A. Seffouh, C. Roelants, I. Seffouh, E. Gout, J. Perard, F. Dalonneau, K. Nishitsuji, F. Noborn, M. Nikpour, G. Larson, Y. Cretinon, M. Friedel-Arboleas, K. Uchimura, R. Daniel, H. Lortat-Jacob, O. Filhol, R.R. Vives
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 11 Pages: 110516-110516
- DOI
  10.1016/j.celrep.2022.110516
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09605
[Journal Article] C-Mannosylated tryptophan-containing WSPW peptide binds to actinin-4 and alters E-cadherin subcellular localization in lung epithelial-like A549?cells2022
- Author(s)
  Ikezaki Midori、Nishitsuji Kazuchika、Matsumura Ko、Manabe Shino、Shibukawa Yukinao、Wada Yoshinao、Ito Yukishige、Ihara Yoshito
- Journal Title
  
  Biochimie
  
  Volume: 192 Pages: 136-146
- DOI
  10.1016/j.biochi.2021.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-21K09476
[Journal Article] Extracellularly Released Calreticulin Induced by Endoplasmic Reticulum Stress Impairs Syncytialization of Cytotrophoblast Model BeWo Cells2021
- Author(s)
  Iwahashi Naoyuki、Ikezaki Midori、Nishitsuji Kazuchika、Yamamoto Madoka、Matsuzaki Ibu、Kato Naoki、Takaoka Naoyuki、Taniguchi Mana、Murata Shin-ichi、Ino Kazuhiko、Ihara Yoshito
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 6 Pages: 1305-1305
- DOI
  10.3390/cells10061305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-20K16198
[Journal Article] Lipid Droplet Accumulation Independently Predicts Poor Clinical Prognosis in High-Grade Serous Ovarian Carcinoma2021
- Author(s)
  Iwahashi Naoyuki、Ikezaki Midori、Fujimoto Masakazu、Komohara Yoshihiro、Fujiwara Yukio、Yamamoto Madoka、Mizoguchi Mika、Matsubara Kentaro、Watanabe Yudai、Matsuzaki Ibu、Murata Shin-ichi、Ihara Yoshito、Ino Kazuhiko、Nishitsuji Kazuchika
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 20 Pages: 5251-5251
- DOI
  10.3390/cancers13205251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-20K09626, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-20K16198
[Journal Article] Cell-to-cell transmission of p53 aggregates: a novel player in oncology?2021
- Author(s)
  Naoyuki Iwahashi, Midori Ikezaki, Hiroyuki Saito, Kenji Uchimura, Kazuchika Nishitsuji
- Journal Title
  
  Molecular & cellular oncology
  
  Volume: 8 Issue: 2 Pages: 1892444-1892444
- DOI
  10.1080/23723556.2021.1892444
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-21K15245
[Journal Article] Novel conformation‐selective monoclonal antibodies against apoA‐I amyloid fibrils2021
- Author(s)
  Takashi Ohgita, Yuki Furutani, Miyu Nakano, Megumi Hattori, Ayane Suzuki, Miho Nakagawa, Sera Naniwa, Izumi Morita, Hiroyuki Oyama, Kazuchika Nishitsuji, Norihiro Kobayashi, Hiroyuki Saito
- Journal Title
  
  FEBS Journal
  
  Volume: 288 Issue: 5 Pages: 1496-1513
- DOI
  10.1111/febs.15487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-21K15245
[Journal Article] Contribution of Sulfated Glycosaminoglycans to the Pathology of Amyloidosis2021
- Author(s)
  K. Nishitsuji, K. Uchimura
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 33 Issue: 196 Pages: E141-E145
- DOI
  10.4052/tigg.2105.1E
- NAID
  130008120295
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2021-11-25
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09605
[Journal Article] Thrombospondin type 1 repeat-derived C-mannosylated peptide attenuates synaptogenesis of cortical neurons induced by primary astrocytes via TGF-β2021
- Author(s)
  Nishitsuji Kazuchika、Ikezaki Midori、Manabe Shino、Uchimura Kenji、Ito Yukishige、Ihara Yoshito
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: - Issue: 5 Pages: 701-710
- DOI
  10.1007/s10719-021-10030-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-21K09476, KAKENHI-PROJECT-22K09623, KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605
[Journal Article] Protein C-Mannosylation and C-Mannosyl Tryptophan in Chemical Biology and Medicine2021
- Author(s)
  Minakata Shiho、Manabe Shino、Inai Yoko、Ikezaki Midori、Nishitsuji Kazuchika、Ito Yukishige、Ihara Yoshito
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 17 Pages: 5258-5258
- DOI
  10.3390/molecules26175258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-21K09476
[Journal Article] Monomeric C-mannosyl tryptophan is a degradation product of autophagy in cultured cells2020
- Author(s)
  Shiho Minakata, Yoko Inai, Shino Manabe, Kazuchika Nishitsuji, Yukishige Ito, Yoshito Ihara
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 37 Issue: 5 Pages: 635-645
- DOI
  10.1007/s10719-020-09938-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-16H06290
[Journal Article] Enhancement of direct membrane penetration of arginine-rich peptides by polyproline II helix structure2020
- Author(s)
  Takashi Ohgita, YukiTakechi-Haraya, KeisukeOkada, Saki Matsui, Misaki Takeuchi, Chihiro Saito, Kazuchika Nishitsuji, Kenji Uchimura, Ryuji Kawano, Koki Hasegawa, Kumiko Sakai-Kato, Kenichi Akaji, Ken-ichi Izutsu, Hiroyuki Saito
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1862 Issue: 10 Pages: 1-11
- DOI
  10.1016/j.bbamem.2020.183403
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-17H03979
[Journal Article] Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates2020
- Author(s)
  Naoyuki Iwahashi, Midori Ikezaki, Taro Nishikawa, Norihiro Namba, Takashi Ohgita, Hiroyuki Saito, Yoshito Ihara, Toshinori Shimanouchi, Kazuhiko Ino, Kenji Uchimura, Kazuchika Nishitsuji
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 117 Issue: 52 Pages: 33225-33234
- DOI
  10.1073/pnas.2009931117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09784, KAKENHI-PROJECT-20K09605, KAKENHI-PROJECT-17H03979
[Journal Article] A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E2019
- Author(s)
  Ohgita Takashi、Takechi-Haraya Yuki、Nadai Ryo、Kotani Mana、Tamura Yuki、Nishikiori Karin、Nishitsuji Kazuchika、Uchimura Kenji、Hasegawa Koki、Sakai-Kato Kumiko、Akaji Kenichi、Saito Hiroyuki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1861 Issue: 3 Pages: 541-549
- DOI
  10.1016/j.bbamem.2018.12.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08749, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-15K21774
[Journal Article] The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity2019
- Author(s)
  Kameyama H, Uchimura K, Yamashita T, Kuwabara K, Mizuguchi M, Hung SC, Okuhira K, Masuda T, Kosugi T, Ohgita T, Saito H, Ando Y, Nishitsuji K.
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 189 Issue: 2 Pages: 308-319
- DOI
  10.1016/j.ajpath.2018.09.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-17K09694, KAKENHI-PROJECT-17K16123
[Journal Article] Effect of Phosphatidylserine and Cholesterol on Membrane-mediated Fibril Formation by the N-terminal Amyloidogenic Fragment of Apolipoprotein A-I2018
- Author(s)
  Mizuguchi Chiharu、Nakamura Mitsuki、Kurimitsu Naoko、Ohgita Takashi、Nishitsuji Kazuchika、Baba Teruhiko、Shigenaga Akira、Shimanouchi Toshinori、Okuhira Keiichiro、Otaka Akira、Saito Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5497-5497
- DOI
  10.1038/s41598-018-23920-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02611, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-17K19492, KAKENHI-PROJECT-17K16123
[Journal Article] Heparan sulfate S-domains and extracellular sulfatases (Sulfs): their possible roles in protein aggregation diseases2018
- Author(s)
  Nishitsuji, K.
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 35 Issue: 4 Pages: 387-396
- DOI
  10.1007/s10719-018-9833-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16123
[Journal Article] Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome2018
- Author(s)
  Nishitsuji Kazuchika、Watanabe Syunsuke、Xiao Jinzhong、Nagatomo Ryosuke、Ogawa Hirohisa、Tsunematsu Takaaki、Umemoto Hitomi、Morimoto Yuki、Akatsu Hiroyasu、Inoue Koichi、Tsuneyama Koichi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16173-16173
- DOI
  10.1038/s41598-018-34571-9
- NAID
  120006842036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-17K16123
[Journal Article] Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies2017
- Author(s)
  H. Kimura, S. Mikawa, C. Mizuguchi, Y. Horie, I. Morita, H. Oyama, T. Ohgita, K. Nishitsuji, A. Takeuchi, S. Lund-Katz, K. Akaji, N. Kobayashi, H. Saito
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 2988-2988
- DOI
  10.1038/s41598-017-03208-8
- NAID
  120006534990
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08953, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-17H03979, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-15K08629
[Journal Article] Analysis of the gut microbiome and plasma short-chain fatty acid profiles in a spontaneous mouse model of metabolic syndrome.2017
- Author(s)
  Analysis of the gut microbiome and plasma short-chain fatty acid profiles in a spontaneous mouse model of metabolic syndrome.
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1) Issue: 1 Pages: 15876-15876
- DOI
  10.1038/s41598-017-16189-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-15K00879
[Journal Article] Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology.2017
- Author(s)
  Zhang Z, Takeda-Uchimura Y, Foyez T, Ohtake-Niimi S, Narentuya, Akatsu H, Nishitsuji K, Michikawa M, Wyss-Coray T, Kadomatsu K, Uchimura K.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 114(14) Issue: 14 Pages: 114-114
- DOI
  10.1073/pnas.1615036114
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01694, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-15K15079, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16H06277
[Journal Article] Sulfated glycosaminoglycans in protein aggregation diseases2017
- Author(s)
  Nishitsuji Kazuchika、Uchimura Kenji
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 34 Issue: 4 Pages: 453-466
- DOI
  10.1007/s10719-017-9769-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-16KK0202
[Journal Article] Animal models for analyzing metabolic syndrome-associated liver diseases2017
- Author(s)
  Tsuneyama Koichi、Nishitsuji Kazuchika、Matsumoto Minoru、Kobayashi Tomoko、Morimoto Yuki、Tsunematsu Takaaki、Ogawa Hirohisa
- Journal Title
  
  Pathology International
  
  Volume: 67 Issue: 11 Pages: 539-546
- DOI
  10.1111/pin.12600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16123
[Journal Article] Enzymatic Remodeling of Heparan Sulfate: A Therapeutic Strategy for Systemic and Localized Amyloidoses?2016
- Author(s)
  Nishitsuji K. Saito H., and Uchimura K.
- Journal Title
  
  Neur. Regener. Res.
  
  Volume: 11 Issue: 3 Pages: 408-409
- DOI
  10.4103/1673-5374.179043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-15K08265
[Journal Article] The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity.2016
- Author(s)
  Nakajima H, Nishitsuji K, Kawashima H, Kuwabara K, Mikawa S, Uchimura K, Akaji K, Kashiwada Y, Kobayashi N, Saito H, Sakashita N
- Journal Title
  
  Amyloid
  
  Volume: 23 Issue: 1 Pages: 17-25
- DOI
  10.3109/13506129.2015.1113167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08265, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-16K08712
[Journal Article] Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes.2016
- Author(s)
  Kameyama H., Nakajima H., Nishitsuji K., Mikawa S., Uchimura K., Kobayashi N., Okuhira K., Saito H., and Sakashita N.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 30391-30391
- DOI
  10.1038/srep30391
- NAID
  120006534966
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-16K08712, KAKENHI-PROJECT-15K08265
[Journal Article] Heparin promotes fibril formation by the N-terminal fragment of amyloidogenic apolipoprotein A-I2016
- Author(s)
  Mikawa, S., Mizuguchi, C., Nishitsuji, K., Baba, T., Shigenaga,A., Shimanouchi, T., Sakashita, N., Otaka, A., Akaji, K., Saito, H.
- Journal Title
  
  FEBS Letters
  
  Volume: 590(20) Issue: 20 Pages: 3492-3500
- DOI
  10.1002/1873-3468.12426
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-16K08712
[Journal Article] C-terminal region of GADD34 regulates eIF2α dephosphorylation and cell proliferation in CHO-K1 cells.2016
- Author(s)
  Otsuka R, Harada N, Aoki S, Shirai K, Nishitsuji K, Nozaki A, Hatakeyama A, Shono M, Mizusawa N, Yoshimoto K, Nakaya Y, Kitahata H, Sakaue H
- Journal Title
  
  Cell stress and chaperones
  
  Volume: 21 Issue: 1 Pages: 2940-2940
- DOI
  10.1007/s12192-015-0633-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26463071, KAKENHI-PROJECT-25350887, KAKENHI-PROJECT-15K19488
[Journal Article] The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity.2016
- Author(s)
  Nakajima H, Nishitsuji K, Kuwabara K, Kawashima H, Uchimura K, Akaji K, Kashiwada Y, Saito H, Sakashita N
- Journal Title
  
  Amyloid
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670190
[Journal Article] アミロイドーシスにおけるヘパラン硫酸多硫酸化ドメイン及びSulf の役割2016
- Author(s)
  西辻　和親、内村　健治
- Journal Title
  
  Medical Science Digest
  
  Volume: 42 Pages: 608-612
- Data Source
  KAKENHI-PROJECT-15K19488
[Journal Article] Enthalpy-driven interactions with sulfated glycosaminoglycans promote cell membrane penetration of arginine peptides.2016
- Author(s)
  Takechi-Haraya Y, Nadai R, Kimura H, Nishitsuji K, Uchimura K, Sakai-Kato K, Ka-wakami K, Shigenaga A, Kawakami T, Otaka A, Hojo H, Sakashita N, Saito H
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: - Issue: 6 Pages: 1339-1349
- DOI
  10.1016/j.bbamem.2016.03.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670190, KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-16K08712, KAKENHI-PROJECT-15K08265
[Journal Article] CUL2-mediated clearance of misfolded TDP-43 is paradoxically affected by VHL in oligodendrocytes in ALS.2016
- Author(s)
  Uchida T, Tamaki Y, Ayaki T, Shodai A, Kaji S, Morimura T, Banno Y, Nishitsuji K, Sakashita N, Maki T, Yamashita H, Ito H, Takahashi R, Urushitani M.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 19118-19136
- DOI
  10.1038/srep19118
- NAID
  120005689210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450403, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-26670190, KAKENHI-PROJECT-24300132, KAKENHI-PROJECT-26290023, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-16K08712
[Journal Article] Arachidonic Acid Diet Attenuates Aβ Deposition in Tg2576 Mice.2015
- Author(s)
  Hosono T, Nishitsuji K, Nakamura T, Jung CG, Kontani M, Tokuda H, Kawashima H, Kiso Y, Suzuki T, Michikawa M
- Journal Title
  
  Brain Res
  
  Volume: 10 Pages: 1613-1629
- DOI
  10.1016/j.brainres.2015.04.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26293010
[Journal Article] CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas: molecular analysis of aggressive invasion and metastasis.2015
- Author(s)
  Ohtomo T, Yoshitani N, Nishitsuji K, Takayama T, Yagagisawa Y, Takeya M, Sakashita N
- Journal Title
  
  Pathology International
  
  Volume: 65 Issue: 5 Pages: 264-270
- DOI
  10.1111/pin.12283
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23590448, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26670190
[Journal Article] K604, a specific acyl-CoA:CoA:cholesterol acyltransferase 1 inhibitor, suppresses proliferation of U251-MG glioblastoma cells2015
- Author(s)
  Ohmoto, Takuji Nishitsuji, Kazuchika Yoshitani, Nobuyuki Mizuguchi, Makoto Yanagisawa, Yuto Saito, Hiroyuki Sakashita, Naomi
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 12 Issue: 4 Pages: 6037-6042
- DOI
  10.3892/mmr.2015.4200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26670190, KAKENHI-PROJECT-25293006
[Journal Article] Cellular Interaction and Cytotoxicity of the Iowa Mutation of Apolipoprotein A-I (ApoA-IIowa) Amyloid Mediated by Sulfate Moieties of Heparan Sulfate2015
- Author(s)
  Kuwabara, K., Nishitsuji, K., Uchimura, K., Hung, S.C., Mizuguchi, M., Nakajima, H., Mikawa, S., Kobayashi, N., Saito, H., and Sakashita, N.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24210-24221
- DOI
  10.1074/jbc.m115.652545
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08265, KAKENHI-PROJECT-15K08629, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-25460709, KAKENHI-PROJECT-25293006
[Journal Article] Specific ayl-CoA:cholesterol acyltransferase inhibitor, K604, suppresses U251-MG glio-blastoma cells proliferation. in press2015
- Author(s)
  Ohmoto T, Nishitsuji K, Yoshitani N, Mizuguchi M, Yanagisawa Y, Saito S, Sakashita N
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 12
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670190
[Journal Article] Arachidonic or docosahexaenoic acid diet prevents memory impairment in Tg2576 mice.2015
- Author(s)
  Hosono T, Mouri A, Nishitsuji K, Jung CG, Kontani M, Tokuda H, Kawashima H, Shibata H, Suzuki T, Nabeshima T, Michikawa M.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 48 Issue: 1 Pages: 149-162
- DOI
  10.3233/jad-150341
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26293010
[Journal Article] ACAT1-associated Late Endosomes/Lysosomes Significantly Improve Impaired Intracellular Cholesterol Metabolism and the Survival of Niemann-Pick Type C Mice2014
- Author(s)
  Kamikawa M, Lei XF, Fujiwara Y, Nishitsuji K, Mizuta H, Takeya M, Sakashita N
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 47 Issue: 2 Pages: 35-43
- DOI
  10.1267/ahc.13033
- NAID
  130003390848
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590448, KAKENHI-PROJECT-25860501, KAKENHI-PROJECT-26670190, KAKENHI-PROJECT-26860588
[Journal Article] Role of ACAT1-positive late endosomes in macrophages: Cholesterol metabolism and therapeutic applications for Niemann-Pick disease type C.2014
- Author(s)
  Sakashita N, Lei XF, Kamikawa M, Nishitsuji K
- Journal Title
  
  Journal of Medical Investigation
  
  Volume: 61 Pages: 270-277
- NAID
  130004822731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] Correlation of the presence of cytoplasmic p53 aggregates with poor prognosis in p53-mutated cancers、p53変異癌における細胞内p53凝集体の予後への影響2024
- Author(s)
  西辻和親、御任玲美、池崎みどり、藤原章雄、岩橋尚幸、井原義人、内村健治、菰原義弘
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] Glycan-Mediated Prion-Like Behavior of Mutant p53 Aggregates and Their Possible Role in Cancer Pathogenesis2023
- Author(s)
  Kazuchika Nishitsuji, Midori Ikezaki, Yoshihiro Komohara, Yukio Fujiwara, Kenji Uchimura, Yoshito Ihara
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] 卵巣がんにおけるタンパク質C-マンノシル化の病態生理応答2023
- Author(s)
  井原義人、井内陽子、岩橋尚幸、南方志帆、森乃絢、池崎みどり、西辻和親、井箟一彦、眞鍋史乃
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] シアロ糖鎖認識抗体CL40 を用いた脂肪滴蓄積を伴う卵巣癌の解析、Analysis of the CL40-reactive sialylated glycans in ovarian cancer associated with lipid droplet accumulation2023
- Author(s)
  西辻和親、池崎みどり、藤本正数、岩橋尚幸、内村健治、井原義人
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] 小胞体ストレス性カルレティキュリン膜移行は細胞性栄養膜細胞でeat-meシグナルとして働く2022
- Author(s)
  西岡香穂, 岩橋尚幸, 南條佐輝子, 池﨑みどり, 西辻和親, 井原義人, 井箟一彦
- Organizer
  第42回一般社団法人日本妊娠高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09601
[Presentation] 小胞体ストレス性カルレティキュリン膜移行は細胞性栄養膜細胞でear-meシグナルとして働く2022
- Author(s)
  西岡香穂、岩橋尚幸、南條佐輝子、池崎みどり、西辻和親、井原義人、井箟一彦
- Organizer
  第42回日本妊娠高血圧学会学術集会、コングレスクエア日本橋（東京都中央区）およびWeb開催
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] 小胞体ストレス性カルレティキュリン膜移行は細胞性栄養膜細胞でear-meシグナルとして働く2022
- Author(s)
  西岡香穂、岩橋尚幸、南條佐輝子、池崎みどり、西辻和親、井原義人、井箟一彦
- Organizer
  第42回日本妊娠高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] C-マンノシル化トリプトファンの細胞による取り込み機構の検討2022
- Author(s)
  南方志帆、井内陽子、西辻和親、眞鍋史乃、井原義人
- Organizer
  第41回日本糖質学会年会、大阪大学コンベンションセンター、大阪大学医学部保健学科講義棟（大阪府吹田市）
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] C-マンノシル化ペプチドはアストロサイト培養上清によるシナプス形成を阻害する2022
- Author(s)
  池崎みどり、西辻和親、眞鍋史乃、内村健治、伊藤幸成、井原義人
- Organizer
  第41回日本糖質学会年会、大阪大学コンベンションセンター、大阪大学医学部保健学科講義棟（大阪府吹田市）
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] 細胞性栄養膜細胞で小胞体ストレスにより膜移行したカルレティキュリンはeat-meシグナルとして働く2022
- Author(s)
  西岡香穂、岩橋尚幸、池崎みどり、西辻和親、井原義人、井箟一彦
- Organizer
  第30回日本胎盤学会学術集会・第40回日本絨毛性疾患研究会、金沢大学十全講堂・医学部記念館（石川県金沢市）およびWeb開催
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] 硫酸化グリコサミノグリカンが仲介するp53凝集体伝播機構とその癌病態への寄与2022
- Author(s)
  西辻和親、池崎みどり、内村健治、岩橋尚幸、西岡香穂、藤原章雄、菰原義弘、井箟一彦、井原義人
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] 細胞性栄養膜細胞で小胞体ストレスにより膜移行したカルレティキュリンはeat-meシグナルとして働く2022
- Author(s)
  西岡香穂、岩橋尚幸、池崎みどり、西辻和親、井原義人、井箟一彦
- Organizer
  第30回日本胎盤学会学術集会・第40回日本絨毛性疾患研究会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] Complementary role of GlcNAc6ST2 and GlcNAc6ST3 in synthesis of CL40-reactive sialylated and sulfated glycans in the pleural mesothelium2022
- Author(s)
  Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Kaho Nishioka, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura
- Organizer
  国際シアロ糖鎖科学会議2022 (Sialoglyco2022), Nagoya University, Aichi, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] 細胞性栄養膜細胞における ERストレスによるカルレティキュリンの細胞表面移行はマクロファージによる貪食に関与する2022
- Author(s)
  西岡香穂、岩橋尚幸、池崎みどり、西辻和親、井箟一彦、井原義人
- Organizer
  第95回日本生化学会大会、名古屋国際会議場（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] 細胞性栄養膜細胞における ERストレスによるカルレティキュリンの細胞表面移行はマクロファージによる貪食に関与する2022
- Author(s)
  西岡香穂、岩橋尚幸、池崎みどり、西辻和親、井箟一彦、井原義人
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] 細胞性栄養膜細胞で小胞体ストレスにより膜移行したカルレティキュリンはeat-meシグナルとして働く2022
- Author(s)
  西岡香穂, 岩橋尚幸, 池﨑みどり, 西辻和親, 井原義人, 井箟一彦
- Organizer
  第30回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09601
[Presentation] Complementary role of GlcNAc6ST2 and GlcNAc6ST3 in synthesis of CL40-reactive sialylated and sulfated glycans in the pleural mesothelium2022
- Author(s)
  Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Kaho Nishioka, Yoshito Ihara, Fabrice Allain, Kazuchika, Nishitsuji, Kenji Uchimura
- Organizer
  国際シアロ糖鎖科学会議2022 (Sialoglyco2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] C-マンノシル化ペプチドはアストロサイト培養上清によるシナプス形成を阻害する2022
- Author(s)
  池崎みどり、西辻和親、眞鍋史乃、内村健治、伊藤幸成、井原義人
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-22K09623
[Presentation] 硫酸化グリコサミノグリカンが仲介するp53凝集体伝播機構とその癌病態への寄与2022
- Author(s)
  西辻和親、池崎みどり、内村健治、岩橋尚幸、西岡香穂、藤原章雄、菰原義弘、井箟一彦、井原義人
- Organizer
  第41回日本糖質学会年会、大阪大学コンベンションセンター、大阪大学医学部保健学科講義棟（大阪府吹田市）
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] C-マンノシル化WSPWペプチドはTGF-βシグナル抑制を介してアストロサイト培養上清によるシナプス形成を阻害する2021
- Author(s)
  池崎みどり，西辻和親，眞鍋史乃，内村健治，伊藤幸成，井原義人
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] p53変異型癌におけるp53凝集体沈着と伝播機構2021
- Author(s)
  西川太朗、岩橋尚幸、池﨑みどり、井原義人、井箟一彦、内村健治、西辻和親
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] p53アミロイド様凝集体の硫酸化糖鎖依存的な細胞間伝播機構の解明2021
- Author(s)
  西川太朗、岩橋尚幸、池﨑みどり、井原義人、井箟一彦、内村健治、西辻和親
- Organizer
  第67回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] グリコサミノグリカン依存的な p53 凝集体伝播機構とその癌病態への寄与2021
- Author(s)
  西辻和親、池﨑みどり、岩橋尚幸、井箟一彦、内村健治、井原義人
- Organizer
  第40回　日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] がん抑制タンパク質p53のアミロイド線維形成性2020
- Author(s)
  南波憲宏、扇田隆司、島内寿德、西辻和親、斎藤博幸
- Organizer
  第70回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] ポリプロリンIIヘリックス構造によるアルギニンペプチド細胞膜透過促進機構2020
- Author(s)
  扇田隆司、原矢佑樹、岡田圭祐、松井早希、竹内美紗紀、齋藤千尋、西辻和親、内村健治、川野竜司、長谷川功紀、加藤くみ子、赤路健一、伊豆津健一、斎藤博幸
- Organizer
  膜シンポジウム2020
- Data Source
  KAKENHI-PROJECT-20K09605
[Presentation] Pathological roles of heparan sulfate S-domains in ATTR amyloidosis2018
- Author(s)
  Kazuchika Nishitsuji, Kenji Uchimura, Taro Yamashita, Kaori Kuwabara, Hirokazu Kameyama, Mineyuki Mizuguchi, Keiichiro Okuhira, Takashi Ohgita, Hiroyuki Saito, Yukio Ando
- Organizer
  XVIth International Symposium on Amyloidosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16123
[Presentation] HS S-domains that accumulate in ATTR amyloidosis patients accelerate and mediate formation and cytotoxicity of transthyretin fibrils2018
- Author(s)
  Kazuchika Nishitsuji, Kenji Uchimura, Taro Yamashita, Hirokazu Kameyama, Kaori Kuwabara, Mineyuki Mizuguchi, Shang-Cheng Hung, Keiichiro Okuhira, Takashi Ohgita, Hiroyuki Saito, Yukio Ando
- Organizer
  2018 ANNUAL MEETING OF THE SOCIETY FOR GLYCOBIOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16123
[Presentation] ATTRアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメインの役割の解明2017
- Author(s)
  亀山泰和、内村健治、山下太郎、水口峰之、坂下直実、斎藤博幸、奥平桂一郎、安東由喜雄、西辻和親
- Organizer
  膜シンポジウム2017　富山
- Data Source
  KAKENHI-PROJECT-17K16123
[Presentation] ATTRアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメイン(S-ドメイン)の役割の解明2017
- Author(s)
  亀山泰和、内村健治、山下太郎、水口峰之、坂下直実、斎藤博幸、奥平桂一郎、安東由喜雄、西辻和親
- Organizer
  第5回日本アミロイドーシス研究会学術集会　京都
- Data Source
  KAKENHI-PROJECT-17K16123
[Presentation] Gut dysbiosis and altered plasma short chain fatty acid profile underlie the pathogenesis of nonalcoholic steatohepatitis.2017
- Author(s)
  Nishitsuji K., Inoue K., Akatsu H., Tsuneyama, K.
- Organizer
  The Liver Meeting 2017 (Walter E. Washington Convention Center, Washington DC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16123
[Presentation] Glycosaminoglycans in protein aggregation diseases.2017
- Author(s)
  Nishitsuji K.
- Organizer
  1st International Conference on the Glycobiology of Nervous System, (Korea University, Seoul, Korea)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16123
[Presentation] ApoAI線維はオートファジー/リソソーム系の機能を障害する。2016
- Author(s)
  亀山泰和、西辻和親、小林典裕、斎藤博幸、坂下直実
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-16K08712
[Presentation] G26R変異型アポリポタンパク質A1線維の細胞毒性はリソソーム依存的である2016
- Author(s)
  亀山泰和、西辻和親、奥平桂一郎、小林典弘、斎藤博幸、坂下直実
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] G26R変異型アポリポタンパク質A1線維の細胞毒性はリソソーム依存的である。2016
- Author(s)
  亀山泰和、西辻和親、奥平桂一郎、小林典裕、斎藤博幸、坂下直実
- Organizer
  第4回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京（東京都・千代田区）
- Year and Date
  2016-08-19
- Data Source
  KAKENHI-PROJECT-16K08712
[Presentation] Sulfated glycosaminoglycans promote cell membrane penetration of arginine peptides via enthalpy-driven interactions.2016
- Author(s)
  灘井亮、原矢佑樹、西辻和親、内村健治、加藤くみ子、重永章、川上徹、大髙章、北條裕信、坂下直実、斎藤博幸
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-16K08712
[Presentation] ApoA-I線維はオートファジー/リソソーム系の機能を障害する2016
- Author(s)
  亀山泰和、西辻和親、小林典裕、斎藤博幸、坂下直実
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] Cellular interaction and cytotoxicity of amyloid fibrils of the Iowa mutant of apolipoprotein A-I (apoA-IIowa) are mediated by sulfate moieties of heparan sulfate.2016
- Author(s)
  Nishitsuji K., Kuwabara K., Uchimura K., Hung SC., Kobayashi N., Saito H., Sakashita N.
- Organizer
  The XVth International Symposium on Amyloidosis
- Place of Presentation
  Uppsala (Sweden)
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] アルギニンペプチドの細胞膜透過はグリコサミノグリカン糖鎖へのエンタルピー依存的結合によって促進される。2016
- Author(s)
  灘井亮、武知佑樹、西辻和親、内村健治、加藤くみ子、重永章、川上徹、大髙章、北條裕信、坂下直実、斎藤博幸
- Organizer
  日本膜学会第38年会
- Place of Presentation
  早稲田大学（東京都・新宿区）
- Year and Date
  2016-05-10
- Data Source
  KAKENHI-PROJECT-16K08712
[Presentation] AApoA-I アミロイドーシスにおけるオートファジー ─ リソソーム系の役割2015
- Author(s)
  亀山泰和, 西辻和親, 小林典裕, 斎藤博幸, 坂下直実
- Organizer
  日本病理学会第61回秋期特別総会
- Place of Presentation
  東京大学安田講堂（東京都文京区）
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] AApoAIアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメインの役割2015
- Author(s)
  桑原香織、西辻和親、山下太郎、小林典裕、内村健治、安東由喜雄、斎藤博幸、坂下直実
- Organizer
  日本アミロイドーシス研究会第3回学術集会
- Place of Presentation
  KKRホテル東京（東京都千代田区）
- Year and Date
  2015-08-20
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] apoA1アミロイドの毒性に対するヘパラン硫酸糖鎖の影響。2015
- Author(s)
  桑原香織、西辻和親、小林典裕、内村健治、斎藤博幸、坂下直実
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場、愛知県、名古屋市
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] AApoA-Iアミロイドーシスにおけるオートファジー・リソソーム系の役割。2015
- Author(s)
  亀山泰和、西辻和親、小林典裕、斎藤博幸、坂下直実
- Organizer
  日本病理学会第61回秋期特別総会
- Place of Presentation
  東京大学、東京都文京区
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] ACAT1陽性後期エンドゾーム陽性腫瘍（ACAT1+/CD44+高悪性度腫瘍）はACAT酵素活性依存性に増殖する。2015
- Author(s)
  坂下直実、大本卓司、吉谷信幸、中須千春、柳澤悠登、西辻和親
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場、愛知県、名古屋市
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] AApoAIアミロイドーシスにおけるヘパラン硫酸多硫酸化ドメインの役割。2015
- Author(s)
  桑原香織、西辻和親、山下太郎、小林典裕、内村健治、安東由喜雄、斎藤博幸、坂下直実
- Organizer
  第3回アミロイドーシス研究会
- Place of Presentation
  KKRホテル東京、東京都千代田区
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] apoA1アミロイドの毒性に対するヘパラン硫酸糖鎖の影響2015
- Author(s)
  桑原香織、西辻和親、小林典裕、内村健治、斎藤博幸、坂下直実
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] ApoA-Iアミロイドの毒性に対するヘパラン硫酸糖鎖の影響。2015
- Author(s)
  西辻和親、桑原香織、小林典裕、内村健治、坂下直実、斎藤博幸
- Organizer
  膜学会37年会
- Place of Presentation
  早稲田大学、東京都新宿区
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] ApoA-Iアミロイドの毒性に対するヘパラン硫酸糖鎖の影響2015
- Author(s)
  西辻和親、桑原香織、小林典裕、内村健治、坂下直実、斎藤博幸
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-15K19488
[Presentation] ApoAIアミロイドの毒性に対するヘパラン硫酸の影響。2014
- Author(s)
  桑原香織、西辻和親、小林典裕、内村健治、堀口英久、坂下直実、斎藤博幸
- Organizer
  第2回日本アミロイドーシス研究会学術集会
- Place of Presentation
  KKRホテル東京、東京千代田区
- Year and Date
  2014-08-22
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] ACAT1陽性後期エンドゾーム陽性腫瘍（ACAT1+/CD44+高悪性度腫瘍）はACAT酵素活性依存性に増殖する
- Author(s)
  坂下直実、大本卓司、吉谷信幸、中須千春、柳澤悠登、西辻和親
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場、愛知県、名古屋市
- Year and Date
  2015-04-30 – 2015-05-02
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] ApoAIアミロイドの毒性に対するヘパラン硫酸の影響。
- Author(s)
  桑原香織、西辻和親、小林典裕、内村健治、斎藤博幸、坂下直実
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場、愛知県、名古屋市
- Year and Date
  2015-04-30 – 2015-05-02
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] 血管外膜出血誘発性血管リモデリングの分子病理学的解析：内膜肥厚形成におけるHeme Oxygenase 1の意義。
- Author(s)
  佐藤綾、小浪裕幸、西辻和親、堀口英久、坂下直実
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場、広島県、広島市
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] 血管外膜出血誘発性血管リモデリングの分子病理学的解析：内膜肥厚形成におけるHeme Oxygenase 1の意義。
- Author(s)
  佐藤綾、小浪裕幸、西辻和親、堀口英久、坂下直実
- Organizer
  第46回日本動脈硬化学会総会
- Place of Presentation
  京王プラザホテル、東京都新宿区
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] ApoAIアミロイドの毒性に対するヘパラン硫酸の影響。
- Author(s)
  桑原香織、西辻和親、小林典裕、内村健治、坂下直実、斎藤博幸
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学医学部、徳島県、徳島市
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-26670190
[Presentation] ApoA-Iアミロイドの毒性に対するヘパラン硫酸糖鎖の影響
- Author(s)
  西辻和親、桑原香織、小林典裕、内村健治、坂下直実、斎藤博幸
- Organizer
  膜学会第37年会
- Place of Presentation
  早稲田大学、東京都新宿区
- Year and Date
  2015-05-14 – 2015-05-15
- Data Source
  KAKENHI-PROJECT-26670190

1. 池崎みどり (40549747)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. 岩橋尚幸 (50750907)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
3. 井箟一彦 (60303640)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
4. SAKASHITA Naomi (90284752)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
5. HORIGUCHI Hidehisa (40304505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 菰原義弘 (40449921)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 井原義人 (70263241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
8. 西岡香穂 (40866787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 藤本正数 (90573676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. JUNG Cha-Gyun

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. HASEGAWA Koki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. OYAMA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. UCHIMURA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 伊藤幸成

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 伊藤隆明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 竹屋元裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 西尾和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 朝比奈裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 山本円

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 斎藤博幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. 大高章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 山下太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 森田いずみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 小林典裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 門松健治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 赤路健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 北畑洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 常山幸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 漆谷真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 守村敏史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishitsuji Kazuchika 西辻 和親

NISHITSUJI Kazuchika 西辻 和親

Research Projects

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Co-Researchers

Effests of p53 aggregates on tumor microenvironment in p53-mutated ovarian cancerPrincipal Investigator

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細胞内脂肪滴蓄積を標的とした子宮頸癌の新たな予後予測と治療戦略

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妊娠高血圧腎症胎盤における硫酸化糖鎖の病態機能解析Principal Investigator

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Relationship between mitochondria-ER interaction in placental development

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p53アミロイドーシスとしてのp53遺伝子変異卵巣癌の病態メカニズムの解明

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Novel mechanism of amyloid beta-induced placentation defectsPrincipal Investigator

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Enzymatic remodeling of heparan sulfate: a therapeutic strategy for systemic amyloidosesPrincipal Investigator

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ACAT1陽性泡沫化腫瘍細胞のコレステロールエステル要求性の解明と治療法の探索

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Role of glycosaminoglycans in ATTR amyloidosisPrincipal Investigator

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Approach to mechanism for post-operative pulmonary vein stenosis: experimental trials for adventitial hemorrhage-associated oxidative stress regulation

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アポトーシス関連M2マクロファージ分化抑制による病態制御－高悪性度腫瘍について

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[Journal Article] GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium2024

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[Journal Article] Functions of Protein <i>C</i>-Mannosylation in Physiology and Pathology2023

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Nishitsuji Kazuchika 西辻和親

NISHITSUJI Kazuchika 西辻和親