Onishi Nobuyuki 大西伸幸

… Alternative Names

ONISHI NOBUYUKI 大西伸幸

ONISHI Nobuyuki 大西伸幸

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Researcher Number	40534540
Other IDs
Affiliation (Current)	2025: 昭和大学, 大学共同利用機関等の部局等, 講師
Affiliation (based on the past Project Information) *help	2025: 昭和大学, 大学共同利用機関等の部局等, 講師 2017 – 2021: 慶應義塾大学, 医学部(信濃町), 訪問研究員 2016: 慶應義塾大学, 医学部(信濃町), 特任助教 2013 – 2014: 慶應義塾大学, 医学部, 特任助教 2011: 慶應義塾大学, 医学部, 特任助教 2010: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Carcinogenesis
Keywords	Principal Investigator In vivoエレクトロポレーション / 神経幹細胞 / Transposaseタンパク質 / Cas9タンパク質 / 遺伝子改変マウス作製法 / 遺伝子改変動物 / ゲノム編集タンパク質 / ゲノム編集 / piggyBacシステム / マウス脳腫瘍モデル … More / ALKキナーゼ / ALKキナーセ / 脳腫瘍モデル / ＡＬＫキナーゼ / 活性型EGFR / 活性型H-RAS / 発がんマウスモデル / 活性型ALK / 神経幹細胞(NSC) / グリオブラストーマ(GBM) / ALK / mouse tumor model / Brain tumor / NSCs Less

腫瘍浸潤リンパ球特異的発現分子群の機能解析Principal Investigator
- Principal Investigator
  
  大西伸幸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Showa University
Development of easy-to-use genome editing protein synthesis system and one-step genetically modified animal production methodPrincipal Investigator
- Principal Investigator
  
  Onishi Nobuyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Development of novel mouse brain tumor model using in vivo electroporation and piggyBac systemPrincipal Investigator
- Principal Investigator
  
  Onishi Nobuyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Keio University
Development of recurrence mouse brain tumor model using inducible iCSCs and identification of target molecules in recurrence tumorPrincipal Investigator
- Principal Investigator
  
  ONISHI NOBUYUKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Keio University
Establishment of human induced cancer stem cells(iCSCs) and malignant brain tumor models derived from neural stem cellsPrincipal Investigator
- Principal Investigator
  
  ONISHI Nobuyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Keio University

All 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 Other

All Journal Article Presentation Other

[Journal Article] Isolation and characterization of neural stem/progenitor cells in the subventricular zone of the naked mole-rat brain2021
- Author(s)
  Yamamura Y, Kawamura Y, Oiwa Y, Oka K, Onishi N, Saya H, Miura K.
- Journal Title
  
  Inflamm Regen.
  
  Volume: 41 Issue: 1 Pages: 31-31
- DOI
  10.1186/s41232-021-00182-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22KJ2509
[Journal Article] Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development2021
- Author(s)
  Moribe F, Nishikori M, Takashima T, Taniyama D, Onishi N, Arima H, Sasanuma H, Akagawa R, Elloumi F, Takeda S, Pommier Y, Morii E, Takaori-Kondo A, Murai J.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Issue: 1 Pages: 0237554-0237554
- DOI
  10.1371/journal.pone.0237554
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-19H03452, KAKENHI-PROJECT-19H03505, KAKENHI-PROJECT-18K08324, KAKENHI-PROJECT-19K22561, KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-16H06279
[Journal Article] The insulin-PI3K-Rac1 axis contributes to terminal adipocyte differentiation through regulation of actin cytoskeleton dynamics2020
- Author(s)
  Kunitomi H, Oki Y, Onishi N, Kano K, Banno K, Aoki D, Saya H, Nobusue H
- Journal Title
  
  Genes to Cells
  
  Volume: 25 Issue: 3 Pages: 165-174
- DOI
  10.1111/gtc.12747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07243, KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-19K06444
[Journal Article] 2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche2020
- Author(s)
  Koike Naoyoshi、Kota Ryuichi、Naito Yoshiko、Hayakawa Noriyo、Matsuura Tomomi、Hishiki Takako、Onishi Nobuyuki、Fukada Junichi、Suematsu Makoto、Shigematsu Naoyuki、Saya Hideyuki、Sampetrean Oltea
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 450-462
- DOI
  10.1038/s42003-020-01165-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07671, KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-20K16801, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-18K07771
[Journal Article] Rock inhibition suppresses osteosarcoma tumorigenesis by inducing terminal adipocyte differentiation in chemoresistant stemlike cells2019
- Author(s)
  1.Takahashi N, Nobusue H, Shimizu T, Sugihara E, Yamaguchi-Iwai S, Onishi N, Kunitomi H, Kuroda T, Saya H
- Journal Title
  
  Cancer Research
  
  Volume: in press Issue: 12 Pages: 3088-3099
- DOI
  10.1158/0008-5472.can-18-2693
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07247, KAKENHI-PROJECT-16J40108, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17H04355, KAKENHI-PROJECT-16H06276
[Journal Article] IMP dehydrogenase-2 Drives Aberrant Nucleolar Activity and Promotes Tumorigenesis in Glioblastoma2019
- Author(s)
  Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sakamoto N, Kitahara S, Wolfe K, Lange L, Onishi N, Uematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT.
- Journal Title
  
  Nat Cell Biol
  
  Volume: 21 Issue: 8 Pages: 1003-1014
- DOI
  10.1038/s41556-019-0363-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07017, KAKENHI-PROJECT-18K07233, KAKENHI-PROJECT-18K08717, KAKENHI-PROJECT-18K08939, KAKENHI-PROJECT-19K07696, KAKENHI-PROJECT-19K18691
[Journal Article] Development of a functional thyroid model based on an organoid culture system.2018
- Author(s)
  Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, Kameyama K, Tsuchihashi K, Sugihara E, Uchino S, Ito K, Kawakubo H, Takeuchi H, Kitagawa Y, Saya H, Nagano O.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 497 Issue: 2 Pages: 783-789
- DOI
  10.1016/j.bbrc.2018.02.154
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07125, KAKENHI-PROJECT-17H03583, KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-17J04061
[Journal Article] Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells.2017
- Author(s)
  Ishimoto T, Miyake K, Nandi T, Yashiro M, Onishi N, Huang KK, Joyce LN, Kalpana R, Tay ST, Suzuki Y, Cho BC, Kuroda D, Arima K, Izumi D, Iwatsuki M, Baba Y, Oki E, Watanabe M, Saya H, Hirakawa K, Baba H, Tan P.
- Journal Title
  
  Gastroenterology
  
  Volume: in press Issue: 1 Pages: 191-204
- DOI
  10.1053/j.gastro.2017.03.046
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-26293290, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-16K07125, KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17K10639, KAKENHI-PROJECT-26293307, KAKENHI-PROJECT-17H01401
[Journal Article] Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity.2017
- Author(s)
  Kamel WA, Sugihara E, Nobusue H, Yamaguchi-Iwai S, Onishi N, Maki K, Fukuchi Y, Matsuo K, Muto A, Saya H, Shimizu T.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 16 Issue: 1 Pages: 182-192
- DOI
  10.1158/1535-7163.mct-16-0499
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J40108, KAKENHI-PROJECT-15K06840, KAKENHI-PROJECT-15K06845, KAKENHI-PROJECT-16K07125
[Journal Article] The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)2016
- Author(s)
  Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H, Nagano O.
- Journal Title
  
  Cancer Research
  
  Volume: in press Issue: 10 Pages: 2954-2963
- DOI
  10.1158/0008-5472.can-15-2121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-14J06883, KAKENHI-PROJECT-25462277, KAKENHI-PROJECT-16K07125, KAKENHI-PROJECT-16K18454
[Journal Article] IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress2014
- Author(s)
  Shimizu T, Sugihara E, Yamaguchi-Iwai S, Tamaki S, Koyama Y, Kamel W, Ueki A, Ishikawa T, Chiyoda T, Osuka S, Onishi N, Ikeda H, Kamei J, Matsuo K, Fukuchi Y, Nagai T, Toguchida J, Toyama Y, Muto A, Saya H
- Journal Title
  
  Cancer Res
  
  Volume: 74 Issue: 22 Pages: 6531-6541
- DOI
  10.1158/0008-5472.can-14-0914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J06657, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24390353, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245, KAKENHI-PROJECT-26830082
[Journal Article] Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation.2014
- Author(s)
  Nobusue H
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3368-3368
- DOI
  10.1038/ncomms4368
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130002, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245
[Journal Article] IGF1 receptor signaling regulates adaptive radioprotection in glioma stemcells2013
- Author(s)
  Osuka S. Sampetrean O, Shimizu T, Saga l, Onishi N, Sugihara E, Okubo J, Fujita S, Takano S, Matsumura A, Saya H
- Journal Title
  
  Stem Cells
  
  Volume: 31 Issue: 4 Pages: 627-640
- DOI
  10.1002/stem.1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00382, KAKENHI-PROJECT-13J06657, KAKENHI-PROJECT-22249055, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-24659645, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245
[Journal Article] Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.2013
- Author(s)
  Oikawa T
- Journal Title
  
  Cancer Res
  
  Volume: 73 Issue: 16 Pages: 5100-5109
- DOI
  10.1158/0008-5472.can-13-0274
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-23659162, KAKENHI-PROJECT-23689020, KAKENHI-PROJECT-25253085, KAKENHI-PROJECT-25830088
[Journal Article] Twist2 functions as a tumor suppressor in murine osteosarcoma cells.2013
- Author(s)
  Ishikawa T, Shimizu T, Ueki A, Yamaguchi S, Onishi N, Sugihara E, Kuninaka S, Miyamoto T, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Mabuchi Y, Matsuzaki Y, Yamaguchi R, Miyano S and Saya H
- Journal Title
  
  Cancer Sci
  
  Volume: (in press) Issue: 7 Pages: 880-888
- DOI
  10.1111/cas.12163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24501320, KAKENHI-PROJECT-24590360, KAKENHI-PROJECT-24592244, KAKENHI-PROJECT-24659789, KAKENHI-PROJECT-25830088, KAKENHI-PROJECT-25860245
[Journal Article] Targeting Aurora B to the equatorial cortex by MKlp2 is required for cytokinesis.2013
- Author(s)
  Kitagawa M, Fung SY, Onishi N, Saya H, Lee SH.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 6 Pages: e64826-e64826
- DOI
  10.1371/journal.pone.0064826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830088
[Journal Article] Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells2012
- Author(s)
  Tamada M, Nagano O, Tateyama S, Ohmura M, Yae T, Ishimoto T, Sugihara E, Onishi N, Yamamoto T, Yanagawa H, Suematsu M, Saya H
- Journal Title
  
  Cancer Res
  
  Volume: 72 Pages: 1438-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700865
[Journal Article] Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor2011
- Author(s)
  Sugihara E, Shimizu T, Kojima K, Onishi N, Kai K, Ishizawa J, Nagata K, Hashimoto N, Honda H, Kanno M, Miwa M, Okada S, Andreeff M and Saya H
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 2849-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700865
[Journal Article] Establishment of a choriocarcinoma model from immortalized normal extravillous trophoblast cells transduced with HRASV122011
- Author(s)
  Kobayashi Y, Shimizu T, Naoe H, Ueki A, Ishizawa J, Chiyoda T, Onishi N, Sugihara E, Nagano O, Banno K, Kuninaka S, Aoki D, Saya H
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 1471-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700865
[Journal Article] Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells2011
- Author(s)
  Motohara T, Masuko S, Ishimoto T, Yae T, Onishi N, Muraguchi T, Hirao A, Matsuzaki Y, Tashiro H, Katabuchi H, Saya H, Nagano O
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Pages: 1597-606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700865
[Journal Article] Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells2011
- Author(s)
  Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Osuka S, Akahata M, Kai K, Sugimoto H, Hirao A, Saya H
- Journal Title
  
  Neoplasia
  
  Volume: 13 Pages: 784-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700865
[Presentation] In vivoエレクトロポレーションを用いたマウス発がんモデルならびに簡便な遺伝子改変マウス作製法の開発2018
- Author(s)
  大西伸幸、大塚正人、佐藤正宏、佐谷秀行
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07125
[Presentation] Development of novel mouse brain tumor model using in vivo electroporation and piggyBac system2016
- Author(s)
  Nobuyuki Onishi, Hideyuki Saya
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K07125
[Presentation] In vivoエレクトロポレーションを用いた新規マウス脳腫瘍モデルの開発2016
- Author(s)
  大西　伸幸
- Organizer
  平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯（長野）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16K07125
[Presentation] Development of mouse brain tumor model using in vivo electroporation and piggyBac system2016
- Author(s)
  Nobuyuki Onishi, Hideyuki Saya
- Organizer
  第14回　幹細胞シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場（兵庫）
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-16K07125
[Presentation] In vivoエレクトロポレーションを用いた新規マウス脳腫瘍モデルの開発2016
- Author(s)
  大西　伸幸、佐谷　秀行
- Organizer
  第43回　BMSコンファレンス (BMS2016)
- Place of Presentation
  ホテルニューアカオ（静岡）
- Year and Date
  2016-07-04
- Data Source
  KAKENHI-PROJECT-16K07125
[Presentation] In vivoエレクトロポレーションを用いた新規マウス脳腫瘍モデルの開発ならびに性状解析2016
- Author(s)
  大西　伸幸、佐谷　秀行
- Organizer
  第4回　がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16K07125
[Presentation] Development and analysis of mouse brain tumor models derived from neural stem cells expressing activated ALK2014
- Author(s)
  Nobuyuki Onishi, Teppei Shimamura, Yasunobu Nagata, Junko Takita, Satoru Miyano, Seishi Ogawa, Hideyuki Saya
- Organizer
  International Symposium on Tumor Biology in Kanazawa & Symposium on Drug Discovery in Academics
- Place of Presentation
  Kanazawa
- Data Source
  KAKENHI-PROJECT-25830088
[Presentation] 神経幹細胞を用いたマウス脳腫瘍モデルの構築2011
- Author(s)
  大西伸幸
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22700865
[Presentation] 誘神経幹細胞を用いたマウス脳腫瘍モデルの構築2011
- Author(s)
  大西伸幸
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22700865
[Presentation] 神経幹細胞を用いたALK 発がんモデルの構築ならびに解析
- Author(s)
  大西伸幸，島村徹平，永田安伸，滝田順子，宮野悟，小川誠司，佐谷秀行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25830088
[Presentation] Oncogenic stressをバイパスするALK発がんシグナルの解析
- Author(s)
  大西伸幸、滝田順子、小川誠司、佐谷秀行
- Organizer
  日本癌学会シンポジウム・共同利用共同研究拠点シンポジウム
- Place of Presentation
  石川県立音楽堂交流ホール (金沢市)
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-25830088
[Presentation] Development and analysis of mouse brain tumor models derived from neural stem cells expressing activated ALK
- Author(s)
  Nobuyuki Onishi, Oltea Sampetrean, Eiji Sugihara, Hideyuki Saya.
- Organizer
  American Association for Cancer Research Annual Meeting 2014
- Place of Presentation
  SAN DIEGO Convention Center （the US)
- Year and Date
  2014-04-05 – 2014-04-11
- Data Source
  KAKENHI-PROJECT-25830088
[]

1. SHIMIZU Takatsune

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. SAKAMOTO Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. SAMPETREAN Oltea

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 森川隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 石本崇胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 信末博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 杉原英志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Onishi Nobuyuki 大西 伸幸

ONISHI NOBUYUKI 大西 伸幸

ONISHI Nobuyuki 大西 伸幸

Research Projects

Research Products

Co-Researchers

腫瘍浸潤リンパ球特異的発現分子群の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of easy-to-use genome editing protein synthesis system and one-step genetically modified animal production methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel mouse brain tumor model using in vivo electroporation and piggyBac systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of recurrence mouse brain tumor model using inducible iCSCs and identification of target molecules in recurrence tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of human induced cancer stem cells(iCSCs) and malignant brain tumor models derived from neural stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Isolation and characterization of neural stem/progenitor cells in the subventricular zone of the naked mole-rat brain2021

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[Journal Article] Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development2021

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[Journal Article] The insulin-PI3K-Rac1 axis contributes to terminal adipocyte differentiation through regulation of actin cytoskeleton dynamics2020

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[Journal Article] 2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche2020

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[Journal Article] Rock inhibition suppresses osteosarcoma tumorigenesis by inducing terminal adipocyte differentiation in chemoresistant stemlike cells2019

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[Journal Article] IMP dehydrogenase-2 Drives Aberrant Nucleolar Activity and Promotes Tumorigenesis in Glioblastoma2019

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[Journal Article] Development of a functional thyroid model based on an organoid culture system.2018

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[Journal Article] Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells.2017

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[Journal Article] Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity.2017

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Onishi Nobuyuki 大西伸幸

ONISHI NOBUYUKI 大西伸幸

ONISHI Nobuyuki 大西伸幸