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Kitatani Kazuyuki  北谷 和之

… Alternative Names

KITATANI Kazuyuki  北谷 和之

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Researcher Number 40539235
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8516-6135
Affiliation (Current) 2025: 摂南大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2024: 摂南大学, 薬学部, 教授
2021 – 2024: 摂南大学, 薬学部, 准教授
2017 – 2022: 東北大学, 東北メディカル・メガバンク機構, 講師
2018: 摂南大学, 薬学部, 講師
2014 – 2016: 東北大学, 東北メディカル・メガバンク機構, 助教 … More
2012: 東北大学, 東北メディカル・メガバンク機構, 助教
2009 – 2011: Tottori University, 医学部附属病院, 助教
2010: Tottori University, 医学部・附属病院, 助教
2010: 鳥取大学, 病院・臨床検査部, 助教 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Pathological medical chemistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Except Principal Investigator
Obstetrics and gynecology / Basic Section 47040:Pharmacology-related / Medium-sized Section 39:Agricultural and environmental biology and related fields / Basic Section 58080:Gerontological nursing and community health nursing-related / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 39040:Plant protection science-related / Basic Section 56050:Otorhinolaryngology-related / Medical sociology
Keywords
Principal Investigator
セラミド / スフィンゴ脂質 / 細胞運動性 / 転移 / 卵巣がん / GBA1 / ゴーシェ病 / p38 / 炎症 / がん … More / ネクロプトーシス / 脂質生物学 / 細胞死 / MLKL / ネクロトーシス / がん転移 / 運動能 / 卵巣癌 / セラミド合成酵素 / セラミドリポソーム / 細胞遊走 / 細胞運動 / p38δ / サイトカイン / 酸性グルコセレブロシダーゼ … More
Except Principal Investigator
スフィンゴ脂質 / 付着器 / 炭疽病菌 / セラミド / 循環腫瘍DNA / 2型自然リンパ球 / アレルゲン免疫療法 / Type 1 regulatory T 細胞 / 細胞外小胞 / アレルギー / リソソーム病 / ニーマンピック病C型 / フェロトーシス / ネクロプトーシス / 卵巣癌 / ステロール / 液胞 / リポソーム / セラミドナノリポソーム / 頭頸部癌 / digital PCR / Digital PCR / 循環腫瘍細胞 / 抗癌剤耐性 / エクソソーム / 婦人科がん / Liquid Biopsy / 放射線感受性 / 化学療法感受性 / 非扁平上皮癌 / 個別化医療 / 集学的治療 / 化学療法 / メタボローム解析 / 難治性がん / 組織亜型 / 子宮頸癌 / 卵胞液 / トランスフェリン / DNA損傷 / 卵管采 / p53変異 / 漿液性腺癌 / 卵巣がん / PAT-1 / 卵巣明細胞腺がん / c-MET / 阻害剤 / c-MET / PAI-1 / 遺伝子解析 / 血栓症 / 卵巣明細胞腺癌 / 治験促進センター / UMIN / JAPIC / HIV感染症研究 / C型肝炎治療薬 / 臨床研究情報検索サイト / 臨床試験 / ICTRP / 臨床試験(治験) / 臨床研究 / Drug lag / International Clinical Trial Research Portal(ICTRP)site / 臨床試験登録サイト / 規制科学 / 薬剤疫学 / 創薬 / 臨床試験(治験) Less
  • Research Projects

    (16 results)
  • Research Products

    (107 results)
  • Co-Researchers

    (28 People)
  •  炭疽病菌の侵入器官形成における液胞―核コミュニケーションの機能解析

    • Principal Investigator
      久保 康之
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 39040:Plant protection science-related
    • Research Institution
      Setsunan University
  •  上皮性卵巣癌におけるネクロプトーシスの臨床的意義と治療標的としての可能性

    • Principal Investigator
      橋本 千明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Tohoku University
  •  フェロミクス解析を用いた褥瘡形成における鉄の病態生理学的役割の解明

    • Principal Investigator
      西田 健太朗
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58080:Gerontological nursing and community health nursing-related
    • Research Institution
      Setsunan University
  •  Exploration and mode of action of therapeutics for treating human refractory lysosomal diseases using an innovative model of anthracnose fungi

    • Principal Investigator
      久保 康之
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 39:Agricultural and environmental biology and related fields
    • Research Institution
      Setsunan University
  •  アレルゲン特異的免疫療法の効果発現における細胞外小胞の役割解明

    • Principal Investigator
      松田 将也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Setsunan University
  •  ネクロプトーシスの脂質性制御とセラミド分子認識の解明Principal Investigator

    • Principal Investigator
      北谷 和之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Setsunan University
  •  頭頸部癌を標的としたセラミドリポソーム製剤による治療探索

    • Principal Investigator
      藤原 和典
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Tottori University
  •  An attempt to establish a new treatment for non-squamous cell carcinoma of the uterine cervix

    • Principal Investigator
      SHIMADA Muneaki
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  roles of ceramide in ovarian cancerPrincipal Investigator

    • Principal Investigator
      kazuyuki kitatani
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Setsunan University
      Tohoku University
  •  Integrated analysis of circulating tumor cells and DNA toward clinical application of liquid biopsy.

    • Principal Investigator
      YAEGASHI Nobuo
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Development of molecular targeted therapy by the inhibition of MET-PAI-1 pathway for the prevention of thrombosis in cancer patients

    • Principal Investigator
      TOYOSHIMA Masafumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Establishment of new therapeutics for ovarian cancer metastasis: ceramide-based therapyPrincipal Investigator

    • Principal Investigator
      KITATANI Kazuyuki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Pathological examination of tubal fimbria and blood circulating DNA measurement toward the ultra-early detection of fallopian tubal cancer

    • Principal Investigator
      YAEGASHI Nobuo
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Regulation of inflammation by sphingolipid salvage pathwayPrincipal Investigator

    • Principal Investigator
      KITATANI Kazuyuki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
      Tottori University
  •  A study of evaluating issue of the drug development scientifically and predicting the adaptive development quantitatively.

    • Principal Investigator
      MAKIE Toshio
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical sociology
    • Research Institution
      Osaka University
      National Hospital Organization Osaka National Hospital Institute for Clinical Reserch
  •  Regulation of sphingolipid signal by acid-β-glucosidasePrincipal Investigator

    • Principal Investigator
      KITATANI Kazuyuki
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tottori University

All 2024 2023 2022 2019 2018 2017 2016 2015 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

  • [Book] "セラミドの細胞内機能概論スフィンゴミエリン合成酵素ファミリー"セラミド-基礎と応用-2011

    • Author(s)
      北谷和之,岡崎俊郎
    • Publisher
      食品化学新聞社
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Book] Advances in Experimental Medicine and Biology("Tools and Techniques for sphingolipid research" Sphingolipids as Signaling and Regulatory Molecules)2010

    • Author(s)
      Kitatani K., Luberto, C.
    • Publisher
      LANDES BIOSCIENCE
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Book] Seibutsu-kogaku Kaishi(Functional liposomes using sphingolipids)882010

    • Author(s)
      Kitatani K.
    • Total Pages
      678
    • Publisher
      The Society for Biotechnology, Japan
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Book] The Cell(Regulation of ceramide by sphingomyelin synthase)2009

    • Author(s)
      Kitatani K., Hashimoto M., Sugimoto Y., Taniguchi M., Okazaki T.
    • Publisher
      Tokyo
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Book] The Lipids(Ceramide and Tumors)202009

    • Author(s)
      Kitatani K.., Okazaki T.
    • Publisher
      Tokyo
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Book] Sphingolipids as Signaling and Regulatory Molecules

    • Author(s)
      Kitatani K., Luberto
    • Publisher
      LANDES BIOSCIENCE(印刷中)
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells2024

    • Author(s)
      Ohya Yuki、Ogiso Yuri、Matsuda Masaya、Sakae Harumi、Nishida Kentaro、Miki Yasuhiro、Fox Todd E.、Kester Mark、Sakamoto Wataru、Nabe Takeshi、Kitatani Kazuyuki
    • Journal Title

      Cells

      Volume: 13 Issue: 5 Pages: 405-405

    • DOI

      10.3390/cells13050405

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06623
  • [Journal Article] La-Related Protein 4 as a Suppressor for Motility of Ovarian Cancer Cells2019

    • Author(s)
      Egiz M, Usui T, Ishibashi M, Zhang X, Shigeta S, Toyoshima M, Kitatani K, Yaegashi N
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 247 Issue: 1 Pages: 59-67

    • DOI

      10.1620/tjem.247.59

    • NAID

      130007556949

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Journal Article] Ceramide nanoliposomes as a MLKL-1-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer2018

    • Author(s)
      Xuewei Zhang, Kazuyuki Kitatani, Masafumi Toyoshima, Masumi Ishibashi, Toshinori Usui, Junko Minato, Mahy Egiz, Shogo Shigeta, Todd Fox, Tye Deering, Mark Kester, Nobuo Yaegashi
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 17 Issue: 1 Pages: 50-59

    • DOI

      10.1158/1535-7163.mct-17-0173

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125, KAKENHI-PROJECT-16K15697
  • [Journal Article] Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer.2018

    • Author(s)
      Ishibashi M, Toyoshima M, Zhang X, Hasegawa-Minato J, Shigeta S, Usui T, Kemp CJ, Grandori C, Kitatani K, Yaegashi N
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 13207-13207

    • DOI

      10.1038/s41598-018-31069-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Journal Article] Regulation of necroptosis by lipids2018

    • Author(s)
      張雪薇 北谷和之
    • Journal Title

      生化学

      Volume: 90 Issue: 6 Pages: 797-800

    • DOI

      10.14952/SEIKAGAKU.2018.900797

    • NAID

      40021783121

    • ISSN
      0037-1017
    • Year and Date
      2018-12-25
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Journal Article] Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers2017

    • Author(s)
      Hasegawa-Minato Junko、Toyoshima Masafumi、Ishibashi Masumi、Zhang Xuewei、Shigeta Shogo、Grandori Carla、Kitatani Kazuyuki、Yaegashi Nobuo
    • Journal Title

      Oncotarget

      Volume: 9(3) Issue: 3 Pages: 3483-3496

    • DOI

      10.18632/oncotarget.23322

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Journal Article] セラミド合成酵素による癌転移制御2016

    • Author(s)
      北谷和之、張 雪薇、臼井利典、豊島将文、重田昌吾、Mahy Egiz、湊 純子、石橋ますみ、小木曽英夫、岡崎俊朗、八重樫伸生
    • Journal Title

      脂質生化学研究

      Volume: 58 Pages: 182-182

    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Journal Article] 卵巣がん細胞に対するセラミドナノリポソームの抗腫瘍効果 -ネクロプト―シスの誘導ー2016

    • Author(s)
      張 雪薇、豊島将文、石橋ますみ、臼井利典、湊 純子、重田昌吾、Mark Kester、北谷和之、八重樫伸生
    • Journal Title

      脂質生化学研究

      Volume: 58 Pages: 68-69

    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Journal Article] Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid2015

    • Author(s)
      Kitatani K, Usui T, Sriraman S, Toyoshima M, Ishibashi M, Shigeta S, Nagase S, Sakamoto M, Hannun Y, Torchilin V, Okazaki T, Ogiso H, Yaegashi N
    • Journal Title

      Oncogene

      Volume: - Issue: 21 Pages: 2801-2812

    • DOI

      10.1038/onc.2015.330

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710, KAKENHI-PROJECT-26861304
  • [Journal Article] Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1:the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer.2015

    • Author(s)
      Shigeta S, Toyoshima M* (*corresponding author), Ishibashi M, Usui T, Kitatani K*, Yaegashi N
    • Journal Title

      Oncogene

      Volume: - Issue: 27 Pages: 3577-3586

    • DOI

      10.1038/onc.2015.425

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
  • [Journal Article] Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer.2015

    • Author(s)
      Mashiko S, Kitatani K, Toyoshima M, Ichimura A, Dan T, Usui T, Ishibashi M, Shigeta S, Nagase S, Miyata T, Yaegashi N
    • Journal Title

      Cancer Biology & Therapy

      Volume: 16 Issue: 2 Pages: 253-260

    • DOI

      10.1080/15384047.2014.1001271

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390375, KAKENHI-PROJECT-24592498, KAKENHI-PROJECT-25860185, KAKENHI-PROJECT-26462509, KAKENHI-PROJECT-26670710
  • [Journal Article] Identification and characterization of PP2C activation by ceramide2012

    • Author(s)
      Perry. D.M., Kitatani K., Roddy P., El-Osta M., Hannun Y.A.
    • Journal Title

      J. Lipid Res

      Volume: 53 Issue: 8 Pages: 1513-1521

    • DOI

      10.1194/jlr.m025395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Journal Article] 国内臨床試験の状況からみるC型慢性肝炎の治療の展望2012

    • Author(s)
      牧江俊雄, 中村剛, 今井優樹, 森永紀, 北谷和之
    • Journal Title

      医薬品医療機器レギュラトリーサイエンス

      Volume: 43 Pages: 446-451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659108
  • [Journal Article] C 型慢性肝炎の治療薬開発を通してみた国内外の臨床試験検索サイトの活用方法の模索2012

    • Author(s)
      牧江 俊雄 黒田 祥平、中村 剛、森永 紀、今井 優樹、北谷 和之
    • Journal Title

      医薬品医療機器レギュラトリーサイエンス

      Volume: 43(5) Pages: 446-451

    • NAID

      40019323065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659108
  • [Journal Article] Regulation of autophagy and its associated cell death by sphingolipid rheostat: Reciprocal role in ceramide and sphingosine-1-phosphate in the mTOR pathway2012

    • Author(s)
      Taniguchi M., Kitatani K., Kondo T., Hashimoto-Nishimura M., Asano S., Hayashi A., Mitsutake S., Igarashi Y., Umehara H., Takeya H., Kigawa J. and Okazaki T.
    • Journal Title

      J. Biol. Chem

      Volume: 287 Issue: 47 Pages: 39898-39910

    • DOI

      10.1074/jbc.m112.416552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790366, KAKENHI-PROJECT-24659469
  • [Journal Article] Regulation of cell migration by sphingomyelin synthases : sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway2012

    • Author(s)
      Asano S, Kitatani K, Taniguchi M, Hashimoto M, Zama K, Mitsutake S, Igarashi Y, Takeya H, Kigawa J, Hayashi A, Umehara H and Okazaki T
    • Journal Title

      Molecular and cellular biology

      Volume: 32 Issue: 16 Pages: 3242-3252

    • DOI

      10.1128/mcb.00121-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249041, KAKENHI-PROJECT-23790366, KAKENHI-PROJECT-24659469
  • [Journal Article] Selective knockdown of ceramide synthases reveals complex inte -regulation of sphingolipid metabolism2011

    • Author(s)
      Mullen T.D., Spassieva S., Jenkins R.W., Kitatani K., Bielawski J., Hannun Y.A., Obeid L.M.
    • Journal Title

      J.Lipid Res. 52

      Pages: 68-77

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Isofagomine in vivo effects in a neuropathic Gaucher disease mouse2011

    • Author(s)
      Sun Y., Ran H., Liou B., Quinn B., Zamzow M., Zhang W., Bielawski J., Kitatani K., Setchell K.D., Hannun Y.A., Witte D.P., Xu Y., Grabowski G.A.
    • Journal Title

      PLoS One in press

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] SMS1-generated sphingomyelin plays an important role in transferring trafficking and cell proliferation2011

    • Author(s)
      Kitatani K., Abdel Shakor A.B., Taniguchi M., Hashimoto M., Asano S., Hayashi A., Nomura K., Bielawski J., Bielawska A., Watanabe K., Kobayashi T., Igarashi Y., Umehara H.
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Pages: 36053-36062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Journal Article] Regulation of death and growth signals at the plasma membrane by sphongomyelin synthesis: implications for hematological malignancies2011

    • Author(s)
      Lafont E., Kitatani K., Okazaki T., and Segui B.
    • Journal Title

      Recent Pat. Anticancer Drug Discov

      Volume: 6 Issue: 3 Pages: 324-333

    • DOI

      10.2174/157489211796957801

    • Data Source
      KAKENHI-PROJECT-23790366
  • [Journal Article] Regulation of CC ligand 5/rantes by acid sphingomyelinase2011

    • Author(s)
      Jenkins R.W., Clarke C.J., Canal D., Snider A.J., Gault C.R., Heffernan-Stroud L., Wu B.X., Simbari F., Roddy P., Kitatani K., Obeid L.M., Hannun Y.A.
    • Journal Title

      J.Biol.Chem. 286

      Pages: 13292-13303

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Inhibitory effects of dietary glucosylceramides on squamous cell carcinoma of the head and neck in NOD/SCID mice2011

    • Author(s)
      Fujiwara K., Kitatani K., Fukushima K., Yazama H., Umehara H., Kikuchi M., Igarashi Y., Kitano H., Okazaki T.
    • Journal Title

      Int.J.Clin.Oncol. 16

      Pages: 133-140

    • NAID

      10029366450

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] セラミドを中心としたスフィンゴ脂質代謝2011

    • Author(s)
      北谷和之,浅野智志,橋本真由美,谷口真,岡崎俊郎
    • Journal Title

      生化学

      Volume: 83 Pages: 495-505

    • NAID

      10029068896

    • Data Source
      KAKENHI-PROJECT-23790366
  • [Journal Article] Specific saposin C deficiency : CNS impairment and aci -β-glucosidase effects in the mouse2010

    • Author(s)
      Sun Y., Ran H., Zamzow M., Kitatani K., Skelton M.R., Williams M.T., Vorhees C.V., Witte D.P., Hannun Y.A., Grabowski G.A.
    • Journal Title

      Human Mol.Genet. 19

      Pages: 634-647

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Specific saposin C deficiency : CNS impairment and acid-β-glucosidase effects in the mouse2010

    • Author(s)
      Sun Y., Ran H., Zamzow M., Kitatani K., Skelton M.R., Williams M.T., Vorhees C.V., Witte D.P., Hannun Y.A., Grabowski G.A.
    • Journal Title

      Human Mol.Genet. 15

      Pages: 634-647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Neuronopathic Gaucher disease in the mouse : Viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) with CNS glucosylsphingosine and glucosylceramide accumulation2010

    • Author(s)
      Sun Y., Liou B., Ran H., Skelton M.R., Williams M.T., Vorhees C.V., Kitatani K., Hannun Y.A., Witte D.P., Xu Y., Grabowski G.A.
    • Journal Title

      Human Mol.Genet. 19

      Pages: 1088-1097

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Regulated secretion of acid sphingomyelinase : implications for selectivity of ceramide formation2010

    • Author(s)
      Jenkins R.W., Canal D., Idkowiak-Baldys J., Simbari F., Roddy P. Perry D.M., Kitatani K., Luberto C., Hannun Y.A.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 35706-35718

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Involvement of acid-β-glucosidase 1 in the salvage pathway of ceramide formation.2009

    • Author(s)
      Kitatani K., Sheldon, K., Anelli, V., Jenkins, R. W., Sun, Y., Grabowski, G. A., Obeid, L. M., Hannun, Y. A.
    • Journal Title

      J.Biol.Chem 284

      Pages: 12972-12978

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Journal Article] Acid-β-glucosidase 1 counteracts p38δ-dependent induction of interleukin-6 : possible role for ceramide as an anti-inflammatory lipid.2009

    • Author(s)
      Kitatani K., Sheldon, K., Anelli, V., Jenkins, R. W., Sun, Y., Grabowski, G. A., Obeid, L. M., Hannun, Y. A.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 12979-12988

    • Data Source
      KAKENHI-PROJECT-21890144
  • [Patent] スフィンコ脂質の製造方法2012

    • Inventor(s)
      北谷和之、岡崎俊朗、平田みよ、北垣浩志
    • Industrial Property Rights Holder
      北谷和之、岡崎俊朗、平田みよ、北垣浩志
    • Industrial Property Number
      2012-090774
    • Filing Date
      2012-05-16
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Patent] スフィンゴ脂質の製造方法2012

    • Inventor(s)
      北谷和之、岡崎俊朗、平田みよ、北垣浩志
    • Industrial Property Rights Holder
      北谷和之、岡崎俊朗、平田みよ、北垣浩志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-05-16
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Presentation] 2型自然リンパ球の活性化に及ぼすTr1細胞由来extracellular vesiclesの影響2024

    • Author(s)
      松田将也、西馬俊祐、渡邊真理、北谷和之、奈邉 健
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K06177
  • [Presentation] Effects of Tr1 cell-derived extracellular vesicles (Tr1-EVs) on activation of ILC2 in a murine model of asthma2024

    • Author(s)
      Masaya Matsuda, Shunsuke Nishiuma, Mari Watanabe, Kazuyuki Kitatani, Takeshi Nabe
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K06177
  • [Presentation] スフィンゴ脂質セラミドによるネクロプトーシスの誘導2023

    • Author(s)
      北谷和之
    • Organizer
      2023年度 第2回Ocular Scientific Meeting(眼科創薬研究会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06623
  • [Presentation] アレルゲン免疫療法により増加するTr1細胞は、細胞外小胞を介して2型自然リンパ球の増殖を抑制する2023

    • Author(s)
      松田将也、西馬俊祐、渡邊真理、北谷和之、奈邉 健
    • Organizer
      第143回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-23K06177
  • [Presentation] 非アポトーシス型の制御性細胞死と脂質性制御2023

    • Author(s)
      北谷和之
    • Organizer
      第1回Ocular Scientific Meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06623
  • [Presentation] 極長鎖セラミドによる細胞死制御2023

    • Author(s)
      小木曽悠里,山澤龍治,松田将也,山地俊之,花田賢太郎,坂本 渉,Daniel Canals,Yusuf A. Hannun,伊藤 潔, 奈邉 健,北谷和之
    • Organizer
      セラミド研究会・スフィンゴテラピイ研究会
    • Data Source
      KAKENHI-PROJECT-22K06623
  • [Presentation] Tr1細胞由来エクソソーム(Tr1-EXO)のアレルギー抑制効果-2型自然リンパ球(ILC2)の活性化に対する効果-2023

    • Author(s)
      渡邊真理、西馬俊祐、松田将也、北谷和之、奈邉 健
    • Organizer
      第73回日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-23K06177
  • [Presentation] 極長鎖セラミド依存的なネクロプトーシスの誘導2022

    • Author(s)
      北谷和之,小木曽悠里,山澤龍治,伊藤 潔,松田将也,山地俊之,花田賢太郎, 坂本 渉,Daniel Canals,Yusuf A. Hannun,奈邉 健
    • Organizer
      セラミド研究会・スフィンゴテラピイ研究会(札幌)
    • Data Source
      KAKENHI-PROJECT-22K06623
  • [Presentation] 第13回スフィンゴテラピ研究会2018

    • Author(s)
      北谷和之,張 雪薇,松田将也,山本雄大,Mark Kester,八重樫伸生,奈邉 健
    • Organizer
      スフィンゴ脂質とプログラム化ネクローシス(ネクロプトーシス)
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] セラミド製剤によるネクロプトーシス誘導2018

    • Author(s)
      北谷和之、張雪 薇、石橋ますみ、豊島將文、松田将也、八重樫伸生、奈邉 健
    • Organizer
      第68回日本薬学会 近畿支部
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] リポソーム化セラミドの抗腫瘍活性:プログラム化ネクローシスの誘2018

    • Author(s)
      北谷和之,張 雪薇,松田将也,Mark Kester,八重樫伸生,奈邉 健
    • Organizer
      第134回日本薬理学会 近畿部会
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] The mechanism of ceramide nanoliposomes-induced necroptosis in ovarian cancer2018

    • Author(s)
      Xuewei Zhang, Kazuyuki Kitatani, Masafumi Toyoshima, Masumi Ishibashi, Shogo Shigeta, Junko Minato, Nobuo Yaegashi
    • Organizer
      第70回日本産科婦人科学会・学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] Role of RNA chaperones in ovarian cancer metastasis2018

    • Author(s)
      Mahy Egiz, Kazuyuki Kitatani, Masafumi Toyoshima, Masumi Ishibashi, Shogo Shigeta, Junko Minato, Nobuo Yaegashi
    • Organizer
      第70回日本産科婦人科学会・学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] Novel implications of La-Related Protein 4, an RNA chaperon, in ovarian cancer metastasis suppression2017

    • Author(s)
      Egiz M, Kitatani K, Toyoshima M, Ishibashi M, Shigeta S, Minato J, Yaegashi N
    • Organizer
      第69回日本産科婦人科学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] Ceramide synthase 2-ceramide synthesis pathway modulates the metastatic potential of ovarian cancer2017

    • Author(s)
      Kitatani K, Zhang X, Toyoshima M, Egiz M, Minato J, Ishibashi M, Shigeta S, Yaegashi N
    • Organizer
      第69回日本産科婦人科学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] 卵巣癌における c-Mycと合成致死作用を持つ 治療標的分子の探索2017

    • Author(s)
      湊 純子、豊島将文、北谷 和之、重田 昌吾、石橋 ますみ、八重樫 伸生
    • Organizer
      第5回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      大阪医科大学 本部北キャンパス(大阪府高槻市)
    • Year and Date
      2017-02-25
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] 卵巣がんに対するセラミドナノリポソーム製剤の抗腫瘍作用2017

    • Author(s)
      張 雪薇、北谷和之、豊島将文、石橋ますみ、臼井利典、湊 純子、重田昌吾、Mark Kester、八重樫伸生
    • Organizer
      第5回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      大阪医科大学 本部北キャンパス(大阪府高槻市)
    • Year and Date
      2017-02-25
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] 卵巣がんに対するセラミドナノリポソーム製剤の抗腫瘍作用2017

    • Author(s)
      張 雪薇、北谷和之、豊島将文、石橋ますみ、臼井利典、湊 純子、重田昌吾、Mark Kester、八重樫伸生
    • Organizer
      第5回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      大阪医科大学 本部北キャンパス(大阪府高槻市)
    • Year and Date
      2017-02-25
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 卵巣癌における c-Mycと合成致死作用を持つ 治療標的分子の探索2017

    • Author(s)
      湊 純子、豊島将文、北谷 和之、重田 昌吾、石橋 ますみ、八重樫 伸生
    • Organizer
      第5回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      大阪医科大学 本部北キャンパス(大阪府高槻市)
    • Year and Date
      2017-02-25
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Potential of ceramide nanoliposomes as necroptosis-inducing chemotherapeutic reagents in ovarian cancer2017

    • Author(s)
      Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Usui T, Minato J, Egiz M, Shigeta S, Fox T, Deering T, Kester M, Yaegashi N
    • Organizer
      15th International Ceramide Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer2017

    • Author(s)
      Ishibashi M, Toyoshima M, Zhang X, Minato J, Shigeta S, Kitatani K, Yaegashi N
    • Organizer
      第69回日本産科婦人科学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] Ceramide synthase 2-ceramide axis limits metastatic potential of ovarian cancer2017

    • Author(s)
      Kitatani K
    • Organizer
      15th International Ceramide Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] 卵巣がん転移制御へのセラミド合成酵素 2 の関与2017

    • Author(s)
      北谷和之、張雪薇、臼井利典、豊島将文、重田昌吾、石橋ますみ、湊純子、小木曽英夫、岡崎俊朗、八重樫伸生
    • Organizer
      第5回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      大阪医科大学 本部北キャンパス(大阪府高槻市)
    • Year and Date
      2017-02-25
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] 卵巣がん転移制御へのセラミド合成酵素 2 の関与2017

    • Author(s)
      北谷和之、張雪薇、臼井利典、豊島将文、重田昌吾、石橋ますみ、湊純子、小木曽英夫、岡崎俊朗、八重樫伸生
    • Organizer
      第5回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      大阪医科大学 本部北キャンパス(大阪府高槻市)
    • Year and Date
      2017-02-25
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Anti-tumor activities of ceramide nanoliposomes in ovarian cancer2017

    • Author(s)
      Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Shigeta S, Minato J, Yaegashi N
    • Organizer
      第69回日本産科婦人科学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] セラミドナノリポソームはネクロプトーシスを誘導する薬剤である2016

    • Author(s)
      張雪薇、豊島将文、石橋ますみ、臼井利典、湊純子、重田昌吾、Mark Kester,北谷和之、八重樫伸生
    • Organizer
      第89回日本生化学会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-27
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] セラミドナノリポソーム製剤によるネクロプト―シスの誘導2016

    • Author(s)
      張 雪薇、北谷 和之、豊島 将文、石橋 ますみ、臼井 利典、湊 純子、重田 昌吾、Mark Kester、八重樫 伸生
    • Organizer
      第9回セラミド研究会 学術集会
    • Place of Presentation
      東京ユビキタス協創広場CANVAS(東京都中央区)
    • Year and Date
      2016-10-27
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Involvement of the receptor tyrosine kinase TIE-1 in the platinum-resistance of ovarian cancer cells2016

    • Author(s)
      Ishibashi M, Toyoshima M, Zhang X, Minato J, Shigeta S, Kitatani K, Yaegashi N
    • Organizer
      Marsha Rikin the 11th Ovarian Cancer Research Symposium
    • Place of Presentation
      ワシントン大学(Seattle, USA)
    • Year and Date
      2016-09-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] セラミド合成酵素による癌転移制御2016

    • Author(s)
      北谷和之,張雪薇,臼井利典,豊島将文,重田昌吾,Mahy Egiz,湊 純子,石橋ますみ,小木曽英夫, 岡崎俊朗,八重樫伸生
    • Organizer
      第58回日本脂質生化学会
    • Place of Presentation
      秋田キャッスルホテル(秋田市)
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Furin, a pro-protein convertase, is a novel molecular target for c-Myc-driven ovarian cancers2016

    • Author(s)
      Minato J, Toyoshima M, Kitatani K, Shigeta S, Ishibashi M, Yaegashi N
    • Organizer
      The 13th International Congress of Human Genetics
    • Place of Presentation
      京都国際会館(京都市)
    • Year and Date
      2016-04-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Transferrin in follicular fluid can facilitate DNA double-strand breaks to fallopian tube epithelium: possible involvement of transferrin in the carcinogenesis of high-grade serous ovarian cancer.2016

    • Author(s)
      Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Masumi Ishibashi, Toshinori Usui, Junko Minato, Nobuo Yaegashi
    • Organizer
      Society for Reproductive Investigation 63th scientific annual meeting
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2016-03-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 卵巣がん転移に関わるセラミド生成代謝酵素2016

    • Author(s)
      北谷和之,張雪薇,臼井利典,豊島将文,重田昌吾,石橋ますみ,湊純子, 小木曽英夫, 岡崎俊朗,八重樫伸生
    • Organizer
      第4回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜市)
    • Year and Date
      2016-02-27
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] Transferrin in follicular fluid can facilitate DNA double-strand breaks to fallopian tube epithelium: possible involvement of transferrin in the carcinogenesis of high-grade serous ovarian cancer.2016

    • Author(s)
      Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Masumi Ishibashi, Toshinori Usui, Junko Minato, Nobuo Yaegashi
    • Organizer
      Society for Reproductive Investigation 63th scientific annual meeting
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2016-03-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] 卵巣がん細胞に対するセラミド卵巣がん細胞に対するセラミドナノリポソームの抗腫瘍効果-ネクロプト-シスの誘導-2016

    • Author(s)
      張 雪薇, 豊島 将文, 石橋 ますみ, 臼井 利典, 湊 純子, 重田 昌吾, Mark Kester, 北谷 和之, 八重樫伸生
    • Organizer
      第58回日本脂質生化学会
    • Place of Presentation
      秋田キャッスルホテル(秋田市)
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Casein kinase I epsilon is a novel molecular target for c-Myc driven ovarian cancers2016

    • Author(s)
      Toyoshima M, Kitatani K, Shigeta S, Ishibashi M, Hasegawa-Minato J, Yaegashi N
    • Organizer
      第68回日本産科婦人科学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-04-22
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 卵巣がん転移に関わるセラミド生成代謝酵素2016

    • Author(s)
      北谷和之,張雪薇,臼井利典,豊島将文,重田昌吾,石橋ますみ,湊純子, 小木曽英夫, 岡崎俊朗,八重樫伸生
    • Organizer
      第4回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜市)
    • Year and Date
      2016-02-27
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 大規模 siRNA スクリーニングを用いた 卵巣がんのシスプラチン抵抗性を 克服する分子標的の検討2016

    • Author(s)
      石橋 ますみ、豊島 将文、Mahy Egiz、張 雪薇、湊 純子、重田 昌吾、北谷 和之、八重樫 伸生
    • Organizer
      第4回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜市)
    • Year and Date
      2016-02-27
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] セラミド合成酵素2による癌転移制御への関与2016

    • Author(s)
      北谷和之、張 雪薇、臼井利典、豊島将文、重田昌吾、Mahy Egiz、湊 純子、石橋ますみ、小木曽英夫、岡崎俊朗、八重樫伸生
    • Organizer
      日本生化学会
    • Place of Presentation
      仙台国際センター/東北大学川内キャンパス(宮城県・仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K11125
  • [Presentation] 卵巣がん転移に関わるセラミド生成代謝酵素2016

    • Author(s)
      北谷和之,張雪薇,臼井利典,豊島将文,重田昌吾,石橋ますみ,湊純子,小木曽英夫, 岡崎俊朗,八重樫伸生
    • Organizer
      第4回婦人科がんバイオマーカー研究会
    • Place of Presentation
      岐阜大学サテライト,岐阜県岐阜市
    • Year and Date
      2016-02-27
    • Data Source
      KAKENHI-PROJECT-26861304
  • [Presentation] セラミドナノリポソームによる新しい細胞死ネクロプトーシス2016

    • Author(s)
      張雪薇、北谷和之、石橋ますみ、湊純子、豊島将文、八重樫伸生
    • Organizer
      第15回日本婦人がん分子標的研究会
    • Place of Presentation
      ホテルニューオータニ札幌(北海道札幌市)
    • Year and Date
      2016-08-20
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 大規模 siRNA スクリーニングを用いた 卵巣がんのシスプラチン抵抗性を 克服する分子標的の検討2016

    • Author(s)
      石橋 ますみ、豊島 将文、Mahy Egiz、張 雪薇、湊 純子、重田 昌吾、北谷 和之、八重樫 伸生
    • Organizer
      第4回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜市)
    • Year and Date
      2016-02-27
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] セラミドナノリポソーム製剤によるネクロプト―シスの誘導2016

    • Author(s)
      張 雪薇、北谷 和之、豊島 将文、石橋 ますみ、臼井 利典、湊 純子、重田 昌吾、Mark Kester、八重樫 伸生
    • Organizer
      第9回セラミド研究会 学術集会
    • Place of Presentation
      東京ユビキタス協創広場CANVAS(東京都中央区)
    • Year and Date
      2016-10-27
    • Data Source
      KAKENHI-PROJECT-16K15697
  • [Presentation] Possible involvement of ceramide synthase in regulatory mechanism of ovarian cancer metastasis.2016

    • Author(s)
      Kazuyuki Kitatani, Zhang Xuewei, Masafumi Toyoshima, Masumi Ishibashi, Shogo Shigeta, Nobuo Yaegashi
    • Organizer
      63th Society for Reproductive Investigation
    • Place of Presentation
      Palais des congres de Montreal,モントリオール,カナダ
    • Year and Date
      2016-03-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861304
  • [Presentation] Transferrin is involved in the carcinogenesis of high-grade serous ovarian cancer by facilitating the DNA double-strand breaks via transferrin receptor 1 in fallopian tube.2016

    • Author(s)
      Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Minato J, Yaegashi N
    • Organizer
      第68回日本産科婦人科学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-04-22
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Transferrin facilitates the formation of DNA-double strand breaks via Transferrin receptor 1 in fallopian tube epithelial cells.2015

    • Author(s)
      Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Junko Minato, Masumi Ishibashi, Toshinori Usui, Nobuo Yaegashi
    • Organizer
      AACR special conference Advance in Ovarian Cancer Research
    • Place of Presentation
      Orland, USA
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 月経血や卵胞液に含まれるトランスフェリンはⅠ型トランスフェリン受容体を介して卵管上皮細胞におけるDNA二重鎖切断を誘導・増幅する2015

    • Author(s)
      重田昌吾・豊島将文・北谷和之・石橋ますみ・八重樫伸生
    • Organizer
      第67回日本産科婦人科学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-04-10
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 月経血や卵胞液に含まれるトランスフェリンはⅠ型トランスフェリン受容体を介して卵管上皮細胞におけるDNA二重鎖切断を誘導・増幅する2015

    • Author(s)
      重田昌吾・豊島将文・北谷和之・石橋ますみ・八重樫伸生
    • Organizer
      第67回日本産科婦人科学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-04-10
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] 卵巣癌におけるc-mycと合成致死作用を持つ治療標的分子の探索2015

    • Author(s)
      湊純子、豊島将文、北谷和之、重田昌吾、石橋ますみ、臼井利典、八重樫伸生
    • Organizer
      第14回日本婦人科がん分子標的研究会
    • Place of Presentation
      美ヶ原温泉ホテル翔峰(長野県松本市)
    • Year and Date
      2015-07-18
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] セラミドによる卵巣がん播種転移制御2015

    • Author(s)
      北谷和之、豊島将文、臼井利典、重田昌吾、石橋ますみ、永瀬智、八重樫伸生
    • Organizer
      第3回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      九州大学医学部百年講堂(福岡市)
    • Year and Date
      2015-02-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] Transferrin facilitates the formation of DNA-double strand breaks via Transferrin receptor 1 in fallopian tube epithelial cells.2015

    • Author(s)
      Shogo Shigeta, Masafumi Toyoshima, Kazuyuki Kitatani, Junko Minato, Masumi Ishibashi, Toshinori Usui, Nobuo Yaegashi
    • Organizer
      AACR special conference Advance in Ovarian Cancer Research
    • Place of Presentation
      Orland, USA
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] セラミドによる卵巣がん播種転移制御2015

    • Author(s)
      北谷和之、豊島将文、臼井利典、重田昌吾、石橋ますみ、永瀬智、八重樫伸生
    • Organizer
      第3回婦人科がんバイオマーカー研究会学術集会
    • Place of Presentation
      九州大学医学部百年講堂(福岡市)
    • Year and Date
      2015-02-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] 卵巣癌におけるc-mycと合成致死作用を持つ治療標的分子の探索2015

    • Author(s)
      湊純子、豊島将文、北谷和之、重田昌吾、石橋ますみ、臼井利典、八重樫伸生
    • Organizer
      第14回日本婦人科がん分子標的研究会
    • Place of Presentation
      美ヶ原温泉ホテル翔峰(長野県松本市)
    • Year and Date
      2015-07-18
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] セラミドによる卵巣がん播種転移制御2015

    • Author(s)
      北谷和之
    • Organizer
      第3回婦人科がんバイオマーカー研究会
    • Place of Presentation
      九州大学医学部百年講堂(福岡市、福岡県)
    • Year and Date
      2015-02-21
    • Data Source
      KAKENHI-PROJECT-26861304
  • [Presentation] Transferrin facilitates DNA-double strand breaks via transferrin receptor 1 in human fallopian tube epithelial cells: possible involvement of transferrin in carcinogenesis.2015

    • Author(s)
      Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Usui T, Yaegashi N
    • Organizer
      Society for Reproductive Investigation 62th scientific annual meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26462509
  • [Presentation] Transferrin facilitates DNA-double strand breaks via transferrin receptor 1 in human fallopian tube epithelial cells: possible involvement of transferrin in carcinogenesis.2015

    • Author(s)
      Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Usui T, Yaegashi N.
    • Organizer
      Society for Reproductive Investigation 62th scientific annual meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26670710
  • [Presentation] p38δ is a novel target for anti-inflammation therapy of Gaucher’s disease2012

    • Author(s)
      Kitatani K.
    • Organizer
      4th Gaucher Leadership Forum, (2012.9)
    • Place of Presentation
      Munich, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Presentation] p38δ is a novel target for anti-inflammation therapy of Gaucher 's disease2012

    • Author(s)
      Kitatani K.
    • Organizer
      4th Gaucher Leadership Forum
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2012-09-22
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Presentation] スフィゴミエリンによる走化性運動の制御2011

    • Author(s)
      浅野智志,北谷和之,谷口真,橋本真由美,武谷浩之,座間宏太,光武進,五十嵐靖之,清川悦子,松田道行,岡崎俊郎
    • Organizer
      第53回脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-13
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Presentation] p38 activation in Gaucher's disease model mice2011

    • Author(s)
      Kitatani K., Perry D., Wada M., Sheldon K., Sun Y., Bielawski J., Anneli V., Obeid LM.,Okazaki T., Grabowski G., Hannun YH.
    • Organizer
      第6回スフィンゴテラピー研究会
    • Place of Presentation
      米子
    • Year and Date
      2011-07-16
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Presentation] Ceramide-mediated XIAP degradation through cathepsin B in IL-2-deprived natural killer cells2011

    • Author(s)
      谷口真, 北谷和之,林輝,田口良光,橋 本真由美,浅野智志,梅原久範,武谷浩之, 岡崎俊郎
    • Organizer
      第53回脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-23790366
  • [Presentation] Regulation of the pro-inflammatory kinase p38 by ceramide generated from acid-β-glucosidase 1 (GBA1) : implications for Gaucher disease2010

    • Author(s)
      北谷和之
    • Organizer
      The 27^<th> NAITO conference on Membrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] 細胞間相互作用によるSMSの新たな機能細胞遊走能,浸潤/転移,homingにおける役割2010

    • Author(s)
      岡崎俊朗, 北谷和之, 谷口真, 橋本真由美, 浅野智志, ルーシー・ワルダハニ
    • Organizer
      第5回スフィンゴテラピー研究会
    • Place of Presentation
      鳥取県米子市
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] スフィンゴミエリンによる走化性運動の制御2010

    • Author(s)
      浅野智志, 北谷和之, 谷口真, 橋本真由美, 武谷浩之, 座間宏太, 光武進, 五十嵐靖之, 岡崎俊朗
    • Organizer
      第5回スフィンゴテラピー研究会
    • Place of Presentation
      鳥取県米子市
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] セラミド依存的なATM活性化によるアポトーシス誘導2010

    • Author(s)
      橋本真由美, 田口佳光, 北谷和之, 谷口真, 浅野智志, ルーシー・ワルダハニ, 武谷浩之, 岡崎俊朗
    • Organizer
      第83回日本生化学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] セラミド依存的なATM活性化によるアポトーシス誘導2010

    • Author(s)
      橋本真由美, 北谷和之, 浅野智志, 五十嵐靖之, 武谷浩之, 岡崎俊朗
    • Organizer
      第5回スフィンゴテラピー研究会
    • Place of Presentation
      鳥取県米子市
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] Regulation of the pro-inflammatory kinase p38 by ceramide generated from acid-β-glucosidase-1 (GBA1) : implications for Gaucher disease.2010

    • Author(s)
      北谷和之
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2010-02-09
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] Regulation of the pro-inflammatory kinase p38 by ceramide generated from acid-β-glucosidase 1 (GBA1) : implications for Gaucher disease2010

    • Author(s)
      Kazuyuki Kitatani
    • Organizer
      The 27^<th> NAITO conference on Membrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      札幌市 シャトレーゼガトーキングダム 札幌
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] スフィンゴシン-1-リン酸(S1P)によるmTOR活性化を介したオートファジー抑制機構2010

    • Author(s)
      谷口真, 北谷和之, 近藤忠一, 橋本真由美, 浅野智志, 五十嵐靖之, 梅原久範, 武谷浩之, 岡崎俊朗
    • Organizer
      第5回スフィンゴテラピー研究会
    • Place of Presentation
      鳥取県米子市
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] Suppression of ceramide-, mediated autophagy by sphingosine-1 phosphate

    • Author(s)
      M.Taniguchi, K.Kitatani, K.Ko ndo, M.Hashimoto, S.Asano, Y.Igarashi, H.Umehara, H.Takeya, T Okazaki
    • Data Source
      KAKENHI-PROJECT-21890144
  • [Presentation] Ceramide Limits Phosphatidylinositol-3-Kinase C2β-Controlled Cell Motility in Ovarian Cancer: Potential of Ceramide liposomes as Antimetastatic Agents

    • Author(s)
      Kazuyuki Kitatani
    • Organizer
      SRI 62nd Annual Scientific Meeting
    • Place of Presentation
      サンフランシスコ(米国)
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26861304
  • 1.  TOYOSHIMA Masafumi (70451581)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 40 results
  • 2.  重田 昌吾 (90842633)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  YAEGASHI Nobuo (00241597)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 4.  久保 康之 (80183797)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  小玉 紗代 (10824039)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  西内 巧 (20334790)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  石橋 ますみ (20821383)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 8.  MAKIE Toshio (80435891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  IMAI Masaki (30440936)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  MORINAGA Osamu (60465771)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  NAKAMURA Tsuyoshi (80039586)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  SHIMADA Muneaki (40362892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKAO Masashi (70216612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  徳永 英樹 (30595559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  永井 智之 (00704298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  藤原 和典 (90403419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  矢間 敬章 (30444631)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  伊藤 潔 (50201926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  橋本 千明 (50821625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  西田 健太朗 (20533805)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  加藤 直樹 (90442946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  松田 将也 (30783005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 23.  奈邉 健 (40228078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 24.  MINATO Junko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 25.  NAGASE Satoru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  岡崎 和一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  岡崎 俊朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  梅原 久範
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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