OIZUMI Takefumi 大泉丈史

Researcher Number	40547262
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2015: 東北大学, 歯学研究科(研究院), 大学院非常勤講師 2012: 東北大学, 大学病院, 医員 2009 – 2012: Tohoku University, 病院, 医員 2010: Tohoku University, 大学病院, その他
Review Section/Research Field	Principal Investigator Surgical dentistry
Keywords	Principal Investigator 顎骨壊死 / ビスフォスフォネート / ビスホスホネート / 骨吸収抑制剤

Research Projects
(3 results)
Research Products
(20 results)

Bisphosphonates related osteonecrosis: Aim to elucidate and treatment mechanismPrincipal Investigator
- Principal Investigator
  
  Oizumi Takefumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
Study of anti-tumor effect and creation of osteonecrosis of the jaw model mice by bone resorption inhibitor bisphosphonatesPrincipal Investigator
- Principal Investigator
  
  OIZUMI Takefumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
骨吸収抑制薬ビスホスホネートの炎症・壊死作用と抗腫瘍作用に関する研究Principal Investigator
- Principal Investigator
  
  大泉丈史
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University

All 2015 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] In vitro cytotoxicity of zoledronate (nitrogen-containing bisphosphonate: NBP) and/or etidronate (non-NBP) in tumourcells and periodontal cells2013
- Author(s)
  Takefumi Oizumi
- Journal Title
  
  Arch Oral Biol
  
  Volume: 58(6) Issue: 6 Pages: 628-37
- DOI
  10.1016/j.archoralbio.2012.11.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791949, KAKENHI-PROJECT-23390439, KAKENHI-PROJECT-23792140, KAKENHI-PROJECT-25861910
[Journal Article] Inhibition of Phosphate Transporters Ameliorates the Inflammatory and Necrotic Side Effects of the Nitrogen-Containing Bisphosphonate Zoledronate in Mice2013
- Author(s)
  Satoru Okada, Tomomi Kiyama, Eri Sato, Yukinori Tanaka, Takefumi Oizumi, Toshinobu Kuroishi, Tetsu Takahashi, Keiichi Sasaki, Shunji Sugawara, Yasuo Endo.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 231 Issue: 2 Pages: 145-158
- DOI
  10.1620/tjem.231.145
- NAID
  130004822384
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861910
[Journal Article] Osteonecrosis of jawbone in 2 osteoporosis patients treated with nitrogen-containing bisphosphonate : Osteonecrosis reduction replacing NBP with non-NBP(etidronate)and rationale2010
- Author(s)
  Oizumi T
- Journal Title
  
  J Oral Maxillofac Surg 68
  
  Pages: 889-897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890018
[Journal Article] Inhibition of Necrotic Actions of Nitrogen-Containing Bisphosphonates(NBPs)and Their Elimination From Bone by Etidronate(a Non-NBP) : A Proposal for Possible Utilization of Etidronate as a Substitution Drug for NBPs2010
- Author(s)
  Takefumi Oizumi
- Journal Title
  
  J Oral Maxillofac Surg 68
  
  Pages: 1043-1054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890018
[Presentation] BRONJ (bisphosphonate-related osteonecrosis of the jaw) の治療：etidronate 置換療法の試み2015
- Author(s)
  大泉丈史
- Organizer
  第３６回東北骨代謝研究会
- Place of Presentation
  江陽グランドホテル（仙台）
- Year and Date
  2015-02-07
- Data Source
  KAKENHI-PROJECT-25861910
[Presentation] BRONJに対するダイドロネルへの置換療法2015
- Author(s)
  大泉丈史
- Organizer
  第３回宮城県口腔外科研究会
- Place of Presentation
  東北大学歯学部（仙台）
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-25861910
[Presentation] Zoledronate の軟組織細胞への取り込み：リン酸transporter関与の可能性．2013
- Author(s)
  岡田諭，木山朋美，大泉丈史，佐々木啓一，高橋哲，菅原俊二，遠藤康男
- Organizer
  歯科基礎医学会
- Place of Presentation
  岡山，岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25861910
[Presentation] 当科におけるビスフォスフォネート投与患者の状況2012
- Author(s)
  大泉丈史
- Organizer
  第57回日本口腔外科学会
- Place of Presentation
  横浜
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] 窒素含有bisphosphonates(NBPs)による顎骨壊死:non-NBPのetidronate(ダイドロネル)への切り換えを試みた5症例2012
- Author(s)
  大泉丈史
- Organizer
  第14回日本骨粗鬆症学会
- Place of Presentation
  新潟
- Year and Date
  2012-09-27
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] 窒素含有 bisphosphonates (NBPs) による顎骨壊死： non-NBP の etidronate (ダイドロネル) への切り換えを試みた５症例2012
- Author(s)
  大泉　丈史
- Organizer
  第14回日本骨粗鬆症学会
- Place of Presentation
  新潟（新潟コンベンションセンター）
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] 当科におけるビスフォスフォネート投与患者の状況2012
- Author(s)
  大泉　丈史
- Organizer
  第57回日本口腔外科学会
- Place of Presentation
  横浜（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] 窒素含有bisphosphonates(NBPs)による顎骨壊死:non-NBPのetidronate(ダイドロネル)への切り換えを試みた5症例2012
- Author(s)
  大泉丈史
- Organizer
  第33回東北骨代謝研究会
- Place of Presentation
  仙台
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] 窒素含有bisphosphonates (NBPs)による顎骨壊死:non-NBPのetidronate(ダイドロネル)への切り換えを試みた5症例2012
- Author(s)
  大泉丈史
- Organizer
  東北骨代謝研究会
- Place of Presentation
  江陽グランドホテル(宮城県)
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] BRONJに対する窒素非含有ビスフォスフォネートへの切り換えの試み2011
- Author(s)
  大泉丈史
- Organizer
  歯科基礎医学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] BRONJに対する窒素非含有ビスフォスフォネートへの切り換えの試み2011
- Author(s)
  大泉丈史
- Organizer
  第56回日本口腔外科学会
- Place of Presentation
  大阪
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] ヒト・マウスの種々の細胞におよぼす zoledronate とetidronate の in vitroでの効果In vitro effects of zoledronate and etidronate on various human and murine cells2011
- Author(s)
  大泉丈史
- Organizer
  第53回歯科基礎医学会
- Place of Presentation
  岐阜
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] ヒト・マウスの種々の細胞におよぼすzoledronateとetidronateのin vitroでの効果2011
- Author(s)
  大泉丈史
- Organizer
  歯科基礎医学会
- Place of Presentation
  長良川国際会議場(岐阜県)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22791949
[Presentation] Bisphosphonates(BPs)の高齢マウス脛骨での効果2009
- Author(s)
  大泉丈史
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟県
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-21890018
[Presentation] 窒素含有 bisphosphonates(N-BPs)の炎症壊死作用:LPS による増強
- Author(s)
  ○鈴木飛佳理，大泉丈史
- Organizer
  第５６回歯科基礎医学会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861910
[Presentation] 窒素含有 bisphosphonates (N-BPs) 治療患者での顎骨壊死：N-BPsのetidronate (non-N-BP) への置換の試み
- Author(s)
  大泉丈史
- Organizer
  第５６回歯科基礎医学会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861910

OIZUMI Takefumi 大泉 丈史

Research Projects

Research Products

Bisphosphonates related osteonecrosis: Aim to elucidate and treatment mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of anti-tumor effect and creation of osteonecrosis of the jaw model mice by bone resorption inhibitor bisphosphonatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨吸収抑制薬ビスホスホネートの炎症・壊死作用と抗腫瘍作用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In vitro cytotoxicity of zoledronate (nitrogen-containing bisphosphonate: NBP) and/or etidronate (non-NBP) in tumourcells and periodontal cells2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Phosphate Transporters Ameliorates the Inflammatory and Necrotic Side Effects of the Nitrogen-Containing Bisphosphonate Zoledronate in Mice2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Osteonecrosis of jawbone in 2 osteoporosis patients treated with nitrogen-containing bisphosphonate : Osteonecrosis reduction replacing NBP with non-NBP(etidronate)and rationale2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of Necrotic Actions of Nitrogen-Containing Bisphosphonates(NBPs)and Their Elimination From Bone by Etidronate(a Non-NBP) : A Proposal for Possible Utilization of Etidronate as a Substitution Drug for NBPs2010

Author(s)

Journal Title

Data Source

[Presentation] BRONJ (bisphosphonate-related osteonecrosis of the jaw) の治療：etidronate 置換療法の試み2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] BRONJに対するダイドロネルへの置換療法2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Zoledronate の軟組織細胞への取り込み：リン酸transporter関与の可能性．2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 当科におけるビスフォスフォネート投与患者の状況2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 窒素含有bisphosphonates(NBPs)による顎骨壊死:non-NBPのetidronate(ダイドロネル)への切り換えを試みた5症例2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 窒素含有 bisphosphonates (NBPs) による顎骨壊死： non-NBP の etidronate (ダイドロネル) への切り換えを試みた ５ 症例2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 当科におけるビスフォスフォネート投与患者の状況2012

Author(s)

Organizer

Place of Presentation

OIZUMI Takefumi 大泉丈史

[Presentation] 窒素含有 bisphosphonates (NBPs) による顎骨壊死： non-NBP の etidronate (ダイドロネル) への切り換えを試みた５症例2012

[Presentation] ヒト・マウスの種々の細胞におよぼす zoledronate とetidronate の in vitroでの効果In vitro effects of zoledronate and etidronate on various human and murine cells2011