HAGIWARA Sumitaka 萩原純孝

… Alternative Names

萩原純孝ハギワラスミタカ

Less

Researcher Number	40547551
Affiliation (Current)	2025: 愛知県がんセンター(研究所), 共通機器室, 研究員
Affiliation (based on the past Project Information) *help	2018: 愛知県がんセンター(研究所), 共通機器室, 研究員 2017: 愛知県がんセンター(研究所), 中央実験室, 研究員 2016: 愛知県がんセンター(研究所), 腫瘍医化学部, 研究員 2015: 愛知県がんセンター(研究所), 中央実験室, 研究員 2011 – 2014: 名古屋大学, 医学部附属病院, 医員 2010: Nagoya University, 医学部附属病院, その他 2009: Nagoya University, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Surgical dentistry
Keywords	Principal Investigator CD109 / TGFβシグナル / 血液腫瘍マーカー / 前癌病変 / 扁平上皮癌 / ＴＧＦβシグナル / エキソソーム / CD44 / 細胞外分泌タンパク質 / 腫瘍マーカー … More / 細胞外分泌 / エクソソーム / 血清CD44 / 血清CD109 / 頭頸部扁平上皮癌 / TGFbetaシグナル / 口腔扁平上皮癌 / 診断マーカー / 免疫組織化学 / 口腔癌 / 細胞増殖 / TGF-βシグナル Less

A study for the development of minimally invasive diagnosis system in oral cancer with TGFbeta-signal regulatory moleculesPrincipal Investigator
- Principal Investigator
  
  HAGIWARA Sumitaka
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Aichi Cancer Center Research Institute
Development of the new squamous cell carcinoma marker that applied TGFbeta-associated extracellular secretion proteinPrincipal Investigator
- Principal Investigator
  
  HAGIWARA Sumitaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagoya University
The study of TGFβ associated novel biomarker that could detect high risk premalignant lesion.Principal Investigator
- Principal Investigator
  
  HAGIWARA Sumitaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagoya University
CD109を応用した口腔扁平上皮癌早期発見のための新規診断マーカーの探究Principal Investigator
- Principal Investigator
  
  萩原純孝
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagoya University

All 2019 2016 2015 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] CD109 is a component of exosome secreted from cultured cells2016
- Author(s)
  Sakakura H, Mii S, Hagiwara S, Kato T, Yamamoto N, Hibi H, Takahashi M, Murakumo Y
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 469 Issue: 4 Pages: 816-822
- DOI
  10.1016/j.bbrc.2015.12.063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670863, KAKENHI-PROJECT-15K20513, KAKENHI-PROJECT-15H02822, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-25293408
[Journal Article] CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells.2015
- Author(s)
  Jing-Min Zhang, Yoshiki Murakumo, Sumitaka Hagiwara, Ping Jiang, Shinji Mii, Emir Kalyoncu, Shoji Saito, Chikage Suzuki, Yasutaka Sakurai, Yoshiko Numata, Toshimichi Yamamoto, Masahide Takahashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Issue: 2 Pages: 252-258
- DOI
  10.1016/j.bbrc.2015.02.093
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670342, KAKENHI-PROJECT-25861926, KAKENHI-PROJECT-15H02822, KAKENHI-PROJECT-25860293
[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma2013
- Author(s)
  Hagiwara S, Yamamoto N, Furue H, Sakakura H, Shigetomi T, Murakumo Y, Hibi H, Takahashi M, Ueda M
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 25 Issue: 3 Pages: 276-287
- DOI
  10.1016/j.ajoms.2012.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659942, KAKENHI-PROJECT-23890080, KAKENHI-PROJECT-24792199
[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma'2012
- Author(s)
  Sumitaka Hagiwara, Noriyuki Yamamoto, Hiroki Furue, Hiroki Sakakura, Toshio Shigetomi, Yoshiki Murakumo, Hideharu Hibi, Masahide Takahashi, Minoru Ueda.
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: Accepted 3
- URL
  http://dx.doi.org/10.1016/j.ajoms.2012.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890080
[Journal Article] Processing of CD109 by furin and its role in the regulation of TGF-β signaling2010
- Author(s)
  S Hagiwara, Y Murakumo, S Mii, T Shigetomi, N Yamamoto, H Furue, M Ueda, M Takahashi
- Journal Title
  
  Oncogene(ADVANCE ONLINE PUBLICATION) January 25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890103
[Presentation] 口腔扁平上皮癌患者における血清CD109の定量解析と臨床的意義に関する検討2019
- Author(s)
  萩原純孝，花井信広，鈴木秀典，西川大輔，小出悠介，別府慎太郎，日比英晴
- Organizer
  第37回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-15K20513
[Presentation] Exosome構成タンパク質としてのCD1092013
- Author(s)
  坂倉寛紀,萩原純孝,山本憲幸,古江浩樹,長嶺健二郎,西川雅也,日比英晴,高橋雅英,上田実
- Organizer
  第58回日本口腔外科学会
- Place of Presentation
  マリンメッセ福岡（福岡市）
- Data Source
  KAKENHI-PROJECT-25861926
[Presentation] CD109は培養細胞においてその培養上清中のExosome上に発現する2013
- Author(s)
  坂倉寛紀,村雲芳樹,三井伸二,萩原純孝,山本憲幸,上田実,高橋雅英
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25861926
[Presentation] 口腔扁平上皮癌におけるCD109の発現～新規腫瘍マーカーとしての有用性の検討～2012
- Author(s)
  萩原純孝
- Organizer
  日本口腔外科学会総会・学術大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23890080
[Presentation] 口腔扁平上皮癌における CD109 の発現～新規腫瘍マーカーとしての有用性の検討～2012
- Author(s)
  萩原純孝、山本憲幸、古江浩樹、坂倉寛紀、西川雅也、日比英晴、高橋雅英、上田実
- Organizer
  第57回日本口腔外科学会総会・学術大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23890080
[Presentation] 口腔白板症の臨床病理学的検討～ハイリスク白板症の早期診断に向けて～2011
- Author(s)
  萩原純孝、山本憲幸、古江浩樹、松本行史、佐藤文仁、和田垣龍、玉利正之、坂倉寛紀、澤村昌嗣、重冨俊雄、上田実
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京:タワーホール船堀
- Data Source
  KAKENHI-PROJECT-23890080
[Presentation] ハイリスク異形上皮の臨床病理学的検討～病理組織像は癌化の可能性を反映するのか？～2011
- Author(s)
  萩原純孝
- Organizer
  第56回日本口腔外科学会総会・学術大会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23890080
[Presentation] ハイリスク異形上皮の臨床病理学的検討～病理組織像は癌化の可能性を反映するのか?～2011
- Author(s)
  萩原純孝、山本憲幸、古江浩樹、和田垣龍、玉利正之、坂倉寛紀、澤村昌嗣、重冨俊雄、上田実
- Organizer
  第56回日本口腔外科学会総会・学術大会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23890080
[Presentation] 口腔癌におけるCD109の発現と生物学的機能の解析2009
- Author(s)
  萩原純孝
- Organizer
  日本口腔外科学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21890103
[Presentation] 浸潤型病変と非浸潤型病変が隣接して発生した舌扁平上皮癌の一例
- Author(s)
  萩原純孝・山本憲幸・西川雅也・古江浩樹・玉利正之・日比英晴・上田実
- Organizer
  第59回日本口腔外科学会総会・学術大会
- Place of Presentation
  千葉県千葉市　会場名：幕張メッセ
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25861926

1. HIBI Hideharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 山本朗仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 斎藤成也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山本敏充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 上田実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAGIWARA Sumitaka 萩原 純孝

萩原 純孝 ハギワラ スミタカ

Research Projects

Research Products

Co-Researchers

A study for the development of minimally invasive diagnosis system in oral cancer with TGFbeta-signal regulatory moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the new squamous cell carcinoma marker that applied TGFbeta-associated extracellular secretion proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of TGFβ associated novel biomarker that could detect high risk premalignant lesion.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CD109を応用した口腔扁平上皮癌早期発見のための新規診断マーカーの探究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CD109 is a component of exosome secreted from cultured cells2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma'2012

Author(s)

Journal Title

URL

Data Source

[Journal Article] Processing of CD109 by furin and its role in the regulation of TGF-β signaling2010

Author(s)

Journal Title

Data Source

[Presentation] 口腔扁平上皮癌患者における血清CD109の定量解析と臨床的意義に関する検討2019

Author(s)

Organizer

Data Source

[Presentation] Exosome構成タンパク質としてのCD1092013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] CD109は培養細胞においてその培養上清中のExosome上に発現する2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 口腔扁平上皮癌におけるCD109の発現～新規腫瘍マーカーとしての有用性の検討～2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 口腔扁平上皮癌における CD109 の発現～新規腫瘍マーカーとしての有用性の検討～2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 口腔白板症の臨床病理学的検討～ハイリスク白板症の早期診断に向けて～2011

Author(s)

Organizer

HAGIWARA Sumitaka 萩原純孝

萩原純孝ハギワラスミタカ