Tomoyose Daisuke 友寄大介 (兒玉大介)

… Alternative Names

Kodama Daisuke 友寄大介

兒玉大介

KODAMA Daisuke 友寄大介(兒玉大介)

兒玉大介コダマダイスケ

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Researcher Number	40549979
Affiliation (Current)	2025: 愛知学院大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2016 – 2019: 愛知学院大学, 薬学部, 講師 2014 – 2015: 愛知学院大学, 歯学部, 講師 2012 – 2014: 愛知学院大学, 歯学部, 助教 2009 – 2010: Aichi Gakuin University, 歯学部, 助教
Review Section/Research Field	Principal Investigator Functional basic dentistry Except Principal Investigator Functional basic dentistry
Keywords	Principal Investigator 交感神経系 / 骨芽細胞 / 交感神経 / 神経科学 / 生理学 / 薬理学 / NK1受容体アンタゴニスト / 鎮痛補助薬 / 三環系抗うつ薬 / NK１遮断薬 … More / NK1受容体遮断薬 / 骨粗鬆症 / 神経障害性疼痛 / 細胞間情報伝達 / 骨代謝 / 感覚神経系 / ATP / グルタミン酸 / 細胞間シグナル伝達 / 感覚神経 / 共培養 / Gタンパク共役型受容体 / Kチャネル / イオンチャネル … More Except Principal Investigator 骨代謝 / 交感神経 / 骨細胞 / 時計遺伝子 / α1-アドレナリン受容体 / 神経 / α-アドレナリン受容体 / 骨芽細胞 / 骨形成 / α1B-アドレナリン受容体 Less

Correlation between mechanical hypersensitivity and bone loss in neuropathic pain model micePrincipal Investigator
- Principal Investigator
  
  Kodama Daisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Does sympathetic nervous system regulate osteocyte function?
- Principal Investigator
  
  Kondo Hisataka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Pharmacological study on increased bone formation by alpha1-adrenoceptor signaling in bone metabolism.
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Intercellular communication between sympathetic or sensory neurons and osteoblasts in co-culture systemPrincipal Investigator
- Principal Investigator
  
  KODAMA Daisuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Involvement of TRPC channels in sympathetically-regulated bone metabolismPrincipal Investigator
- Principal Investigator
  
  KODAMA Daisuke
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University

All 2019 2018 2017 2016 2015 2014 2013 2011 2010 Other

All Journal Article Presentation

[Journal Article] Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system.2017
- Author(s)
  Kodama Daisuke, Hirai Takao, Kondo Hisataka, Hamamura Kazunori, Togari Akifumi.
- Journal Title
  
  FEBS Letters
  
  Volume: 591(3) Issue: 3 Pages: 527-539
- DOI
  10.1002/1873-3468.12561
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K11061, KAKENHI-PROJECT-16K11495
[Journal Article] Pharmacological blockade of 5-HT2B receptor signaling impairs bone formation in mice.2016
- Author(s)
  Tanaka K, Hirai T, Kondo H, Kodama D, Hamamura K, Togari A
- Journal Title
  
  Aichi Gakuin Dental Science
  
  Volume: 173 Pages: 1058-1069
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462827
[Journal Article] α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts.2016
- Author(s)
  Tanaka K, Hirai T, Kodama D, Kondo H, Hamamura K, Togari A.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 173(6) Issue: 6 Pages: 1058-1069
- DOI
  10.1111/bph.13418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11061, KAKENHI-PROJECT-26462827
[Journal Article] Pharmacological Blockade of 5-HT2B Receptor Signaling Impairs Bone Formation in Mice2016
- Author(s)
  Kenjiro Tanaka, Takao Hirai, Daisuke Kodama, Hisataka Kondo, Kazunori Hamamura, Akifumi Togari.
- Journal Title
  
  Aichi Gakuin Dental Science
  
  Volume: 29 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11061
[Journal Article] Shear stress-induced Ca2+ elevation is mediated by autocrine-acting glutamate in osteoblastic MC3T3-E1 cells2015
- Author(s)
  Norika Tsuchiya, Daisuke Kodama, Shigemi Goto, Akifumi Togari
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 127 Issue: 3 Pages: 311-318
- DOI
  10.1016/j.jphs.2015.01.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24791988
[Journal Article] Regulation of bone metabolism by sympathetic nervous system2015
- Author(s)
  戸苅彰史、近藤久貴、平居貴生、兒玉大介、新井通次、後藤滋巳
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 145 Issue: 3 Pages: 140-145
- DOI
  10.1254/fpj.145.140
- NAID
  130004827729
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-26462827
[Journal Article] Signaling pathway and physiological role of alpha-1 adrenergic receptor in human osteoblast.2014
- Author(s)
  Kodama D, Togari A
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 56 Issue: 3 Pages: 73-76
- DOI
  10.1016/j.job.2014.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462827
[Journal Article] Modulation of potassium channels via the α_<1B>-adrenergic receptor in human osteoblast2010
- Author(s)
  Daisuke, Kodama, Akifumi Togari
- Journal Title
  
  Neuroscience Letters
  
  Volume: 485 Pages: 102-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890276
[Journal Article] Modulation of potassium channels via the α_<1B>-adrenergic receptor inhuman osteoblast.2010
- Author(s)
  Daisuke Kodama, Akifumi Togari
- Journal Title
  
  Neuroscience letters 485
  
  Pages: 102-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] 骨粗鬆症を伴う神経障害性疼痛モデルマウスにおけるamitriptylineの骨保護作用2019
- Author(s)
  兒玉大介，大井義明，櫨彰
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] 神経傷害による痛みおよび骨減少に対するアミトリプチリンの治療効果2019
- Author(s)
  兒玉大介，大井義明，櫨彰
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] Therapeutic effects of an NK1 receptor antagonist on mechanical hypersensitivity and bone loss in partial sciatic nerve ligated mice2018
- Author(s)
  Daisuke Kodama, Yoshiaki Ohi, Akira Haji
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] Therapeutic effects of an NK1 receptor antagonist on mechanical hypersensitivity and bone loss in partial sciatic nerve ligated mice2018
- Author(s)
  Daisuke Kodama, Yoshiaki Ohi, Akira Haji
- Organizer
  18th World Congress of basic and clinical Pharmacology
- Invited
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] 神経障害性疼痛モデルマウスに対するNK1受容体遮断薬の鎮痛および骨減少抑制作用2018
- Author(s)
  兒玉大介，大井義明，櫨彰
- Organizer
  第64回日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] Change of bone metabolism in partial sciatic nerve ligated mice2017
- Author(s)
  兒玉　大介、大井　義明、櫨　彰
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] 坐骨神経部分結紮モデルマウスにおける骨の変化2017
- Author(s)
  兒玉大介、大井義明、櫨彰
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K20430
[Presentation] 共培養系における感覚神経ー骨芽細胞間の相互シグナル伝達2016
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第８９回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川、横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K11061
[Presentation] Bidirectional communication between sensory neuronal cells and osteoblasts in an in vitro co-culture system2014
- Author(s)
  兒玉　大介、戸苅　彰史
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 骨芽細胞の機械刺激応答におけるグルタミン酸放出の役割2014
- Author(s)
  土屋範果、兒玉大介、後藤滋巳、戸苅彰史
- Organizer
  第49回骨Ca代謝研究会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-27
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 骨芽細胞様細胞におけるずり応力による細胞内カルシウム濃度の上昇にグルタミン酸が関与する2013
- Author(s)
  土屋　範果、兒玉　大介、後藤　滋巳、戸苅　彰史
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 骨芽細胞と神経細胞の共培養実験法の確立と細胞間相互作用の検討2013
- Author(s)
  兒玉　大介、戸苅　彰史
- Organizer
  日本口腔組織培養学会設立50周年記念学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 骨芽細胞の機械刺激によるCa2+シグナルへのグルタミン酸の関与2013
- Author(s)
  土屋　範果、兒玉　大介、後藤　滋巳、戸苅　彰史
- Organizer
  日本口腔組織培養学会設立50周年記念学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 骨芽細胞様細胞における機械刺激による細胞内カルシウム濃度の上昇にグルタミン酸が関与する2013
- Author(s)
  土屋　範果、兒玉　大介、後藤　滋巳、戸苅　彰史
- Organizer
  第72回日本矯正歯科学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] Modulation of potassium channels via the α_<1B>-adrenergic receptor in human osteoblasts.2011
- Author(s)
  兒玉大介,戸苅彰史
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] Modulation of potassium channels via the α_<1B>-adrenergic receptor in human osteoblasts2011
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] ヒト骨芽細胞におけるα_<1B>-アドレナリン受容体を介したKチャネルの抑制2010
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] ヒト骨芽細胞におけるα_<1B>-アドレナリン受容体を介したKチャネルの抑制2010
- Author(s)
  兒玉大介,戸苅彰史
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] ヒト骨芽細胞SaM-1におけるα_<1B>-アドレナリン受容体刺激のシグナル伝達経路について2010
- Author(s)
  兒玉大介,戸苅彰史
- Organizer
  第47回日本口腔組織培養学会学術大会
- Place of Presentation
  高知
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] ヒト骨芽細胞SaM-1におけるα_<1B>-アドレナリン受容体刺激のシグナル伝達経路について2010
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第47回日本口腔組織培養学会学術大会
- Place of Presentation
  高知県教育会館高知城ホール
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21890276
[Presentation] 神経-骨芽細胞共培養系における細胞間シグナル伝達
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] In vitro共培養系における骨芽細胞から感覚神経へのシグナル伝達
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第34回日本歯科薬物療法学会学術大会
- Place of Presentation
  大阪
- Year and Date
  2014-06-21 – 2014-06-22
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 骨芽細胞における機械刺激によるグルタミン酸放出とその生理的役割
- Author(s)
  土屋範果、兒玉大介、後藤滋巳、戸苅彰史
- Organizer
  第73回日本矯正歯科学会大会
- Place of Presentation
  千葉
- Year and Date
  2014-10-20 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-24791988
[Presentation] 神経伝達物質の放出を介した感覚神経-骨芽細胞間の相互シグナル伝達
- Author(s)
  兒玉大介、戸苅彰史
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24791988

1. TOGARI Akifumi (80126325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. Kondo Hisataka (40469002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 平居貴生 (80389072)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 浜村和紀 (00422767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results

Tomoyose Daisuke 友寄 大介 (兒玉 大介)

Kodama Daisuke 友寄 大介

兒玉大介

KODAMA Daisuke 友寄 大介(兒玉大介)

兒玉 大介 コダマ ダイスケ

Research Projects

Research Products

Co-Researchers

Correlation between mechanical hypersensitivity and bone loss in neuropathic pain model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Does sympathetic nervous system regulate osteocyte function?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pharmacological study on increased bone formation by alpha1-adrenoceptor signaling in bone metabolism.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intercellular communication between sympathetic or sensory neurons and osteoblasts in co-culture systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of TRPC channels in sympathetically-regulated bone metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacological blockade of 5-HT2B receptor signaling impairs bone formation in mice.2016

Author(s)

Journal Title

Data Source

[Journal Article] α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacological Blockade of 5-HT2B Receptor Signaling Impairs Bone Formation in Mice2016

Author(s)

Journal Title

Data Source

[Journal Article] Shear stress-induced Ca2+ elevation is mediated by autocrine-acting glutamate in osteoblastic MC3T3-E1 cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of bone metabolism by sympathetic nervous system2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Signaling pathway and physiological role of alpha-1 adrenergic receptor in human osteoblast.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of potassium channels via the α_<1B>-adrenergic receptor in human osteoblast2010

Author(s)

Journal Title

Data Source

[Journal Article] Modulation of potassium channels via the α_<1B>-adrenergic receptor inhuman osteoblast.2010

Author(s)

Tomoyose Daisuke 友寄大介 (兒玉大介)

Kodama Daisuke 友寄大介

KODAMA Daisuke 友寄大介(兒玉大介)

兒玉大介コダマダイスケ