Tsunaka Yasuo 津中康央 (津中康央)

… Alternative Names

津中康央

津中康央ツナカヤスオ

TSUNAKA Yasuo 津中康央

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Researcher Number	40551552
Other IDs	https://orcid.org/0000-0002-7366-7610
Affiliation (Current)	2025: 横浜市立大学, 生命医科学研究科, 客員研究員 2025: 大阪大学, 大学院工学研究科, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2023: 大阪大学, 大学院工学研究科, 特任助教(常勤) 2022: 大阪大学, 大学院工学研究科, 特任講師(常勤) 2018 – 2021: 横浜市立大学, 生命医科学研究科, 特任助教 2016: 京都大学, 物質-細胞統合システム拠点, 特任講師 2013 – 2014: 京都大学, 物質-細胞統合システム拠点, 特任講師
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related Except Principal Investigator Structural biochemistry
Keywords	Principal Investigator ヌクレオソーム / 構造生物学 / クロマチンリモデリング / FACT / ヒストンテイル / ヒストン交換 / ヒストンバリアント Except Principal Investigator 構造生物学 / クロマチンリモデリング / DNAトランスアクション / 発現制御 / クロマチン / 核内受容体

Structural basis for histone discrimination mechanism by FACTPrincipal Investigator
- Principal Investigator
  
  津中康央 (津中康央)
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Osaka University
  Yokohama City University
Structural basis for nucleosome reconstitution mechanism by FACTPrincipal Investigator
- Principal Investigator
  
  Tsunaka Yasuo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Osaka University
  Yokohama City University
Molecular mechanism of chromatin remodeling coupled with DNA transaction
- Principal Investigator
  
  Morikawa Kosuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
  International Institute for Advanced Studies
Structural Basis for the chromatin remodeling by nuclear receptors
- Principal Investigator
  
  MORIKAWA Kosuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  International Institute for Advanced Studies

All 2022 2021 2020 2019 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes2022
- Author(s)
  Tsunaka Yasuo、Ohtomo Hideaki、Nishimura Yoshifumi
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 814-814
- DOI
  10.1038/s42003-022-03785-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06021, KAKENHI-PROJECT-18K06064
[Journal Article] Histone tail network and modulation in a nucleosome2022
- Author(s)
  Tsunaka Yasuo、Furukawa Ayako、Nishimura Yoshifumi
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 75 Pages: 102436-102436
- DOI
  10.1016/j.sbi.2022.102436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06021, KAKENHI-PUBLICLY-21H05756, KAKENHI-PROJECT-18K06064
[Journal Article] Dynamic structures of intrinsically disordered proteins related to the general transcription factor TFIIH, nucleosomes, and histone chaperones2022
- Author(s)
  Okuda Masahiko、Tsunaka Yasuo、Nishimura Yoshifumi
- Journal Title
  
  Biophysical Reviews
  
  Volume: 14 Issue: 6 Pages: 1449-1472
- DOI
  10.1007/s12551-022-01014-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06021, KAKENHI-PROJECT-21K06035, KAKENHI-PROJECT-18K06064
[Journal Article] Partial Replacement of Nucleosomal DNA with Human FACT Induces Dynamic Exposure and Acetylation of Histone H3 N-Terminal Tails2020
- Author(s)
  Tsunaka Yasuo、Ohtomo Hideaki、Morikawa Kosuke、Nishimura Yoshifumi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 10 Pages: 101641-101641
- DOI
  10.1016/j.isci.2020.101641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06064
[Journal Article] Structural visualization of key steps in nucleosome reorganization by human FACT2019
- Author(s)
  Mayanagi Kouta、Saikusa Kazumi、Miyazaki Naoyuki、Akashi Satoko、Iwasaki Kenji、Nishimura Yoshifumi、Morikawa Kosuke、Tsunaka Yasuo
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10183-10183
- DOI
  10.1038/s41598-019-46617-7
- NAID
  120007133123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07313, KAKENHI-PROJECT-18K06064, KAKENHI-PUBLICLY-18H04561, KAKENHI-PROJECT-18K06089
[Journal Article] FACT Creates a Transiently Accessible Nucleosome Structure Through Integrated Reorganization Mechanism2016
- Author(s)
  Yasuo Tsunaka & Kosuke Morikawa
- Journal Title
  
  Biochemistry & molecular biology journal
  
  Volume: 2 Issue: 03
- DOI
  10.21767/2471-8084.100028
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26251008
[Journal Article] Integrated molecular mechanism directing nucleosome reorganization by human FACT2015
- Author(s)
  Tsunaka Y, Fujiwara Y, Oyama T, Hirose S, Morikawa K
- Journal Title
  
  Genes Dev
  
  Volume: 30(6) Issue: 6 Pages: 673-686
- DOI
  10.1101/gad.274183.115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24370046, KAKENHI-PROJECT-26251008, KAKENHI-PROJECT-26440023
[Journal Article] Phosphorylation-coupled Intramolecular Dynamics of Unstructured Regions in Chromatin Remodeler FACT2013
- Author(s)
  M.Hashimoto, N.Kodera, Y.Tsunaka, M.Oda, M.Tanimoto, T.Ando, K.Morikawa, and S.Tate
- Journal Title
  
  Biophys. J.
  
  Volume: 104 Issue: 10 Pages: 2222-2234
- DOI
  10.1016/j.bpj.2013.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21113002, KAKENHI-PROJECT-23247016, KAKENHI-PROJECT-24227005, KAKENHI-PROJECT-24770149
[Presentation] 相関構造生物学によるFACTを介したヒストンH3テイルの動的構造変化の解明2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K06021
[Presentation] FACT蛋白質はヌクレオソームの動的構造変化を誘導し、そのアクセスビリティを制御する2021
- Author(s)
  津中康央
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] FACTを介したヒストンH2A、H2Bテイルの動的構造変化の解明2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06021
[Presentation] FACTによるクロマチンリモデリングで鍵となるヒストンH3テイルの動的挙動2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第14回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] FACT蛋白質はヌクレオソームの動的構造変化を誘導し、そのアクセスビリティを制御する2021
- Author(s)
  津中康央
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06021
[Presentation] FACTを介したヒストンH2A、H2Bテイルの動的構造変化の解明2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] クライオ電顕構造とNMR解析を組み合わせてFACTを介したヒストンテイルの動的構造変化にせまる2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K06021
[Presentation] 相関構造生物学によるFACTを介したヒストンH3テイルの動的構造変化の解明2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] クライオ電顕構造とNMR解析を組み合わせてFACTを介したヒストンテイルの動的構造変化にせまる2021
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] FACT-ヌクレオソーム複合体の電顕構造では可視化できないヒストンテイルの動的挙動をNMRで明らかにする2020
- Author(s)
  津中康央, 大友秀明, 森川耿右, 西村善文
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] ヌクレオソーム構造変換におけるFACT酸性天然変性領域の新たな分子機能2018
- Author(s)
  津中康央、真柳浩太、七種和美、宮崎直幸、明石知子、岩崎憲治、西村善文、森川耿右
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06064
[Presentation] FACTを介したクロマチンリモデリングの分子機構2017
- Author(s)
  津中康央、森川耿右
- Organizer
  第11回エピジェネティクス研究会
- Place of Presentation
  東京一ツ橋学術総合センター
- Year and Date
  2017-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26251008
[Presentation] FACTを介したクロマチンリモデリング機構の構造基盤2017
- Author(s)
  津中康央、森川耿右
- Organizer
  ワークショップ「染色体研究の最前線」
- Place of Presentation
  大阪大学生命科学研究科生命システム棟
- Year and Date
  2017-01-16
- Invited
- Data Source
  KAKENHI-PROJECT-26251008
[Presentation] FACTを介したクロマチンリモデリングの分子機構2016
- Author(s)
  津中康央、藤原芳江、大山拓次、広瀬進、森川耿右
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26251008
[Presentation] FACTを介したクロマチンリモデリングの分子機構2016
- Author(s)
  津中康央、藤原芳江、大山拓次、広瀬進、森川耿右
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-26251008

1. MORIKAWA Kosuke (80012665)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. FUKAGAWA Tatsuo (60321600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ANDO Toshio (50184320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. MAYANAGI Kota (50418571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OYAMA Takuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 明石知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsunaka Yasuo 津中 康央 (津中 康央)

津中康央

津中 康央 ツナカ ヤスオ

TSUNAKA Yasuo 津中 康央

Research Projects

Research Products

Co-Researchers

Structural basis for histone discrimination mechanism by FACTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural basis for nucleosome reconstitution mechanism by FACTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of chromatin remodeling coupled with DNA transaction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural Basis for the chromatin remodeling by nuclear receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histone tail network and modulation in a nucleosome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic structures of intrinsically disordered proteins related to the general transcription factor TFIIH, nucleosomes, and histone chaperones2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Partial Replacement of Nucleosomal DNA with Human FACT Induces Dynamic Exposure and Acetylation of Histone H3 N-Terminal Tails2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural visualization of key steps in nucleosome reorganization by human FACT2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] FACT Creates a Transiently Accessible Nucleosome Structure Through Integrated Reorganization Mechanism2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrated molecular mechanism directing nucleosome reorganization by human FACT2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylation-coupled Intramolecular Dynamics of Unstructured Regions in Chromatin Remodeler FACT2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 相関構造生物学によるFACTを介したヒストンH3テイルの動的構造変化の解明2021

Author(s)

Organizer

Data Source

[Presentation] FACT蛋白質はヌクレオソームの動的構造変化を誘導し、そのアクセスビリティを制御する2021

Author(s)

Organizer

Data Source

Tsunaka Yasuo 津中康央 (津中康央)

津中康央ツナカヤスオ

TSUNAKA Yasuo 津中康央