YOSHINO Kazuhisa 吉野和寿

Researcher Number	40551859
Other IDs
Affiliation (based on the past Project Information) *help	2015: 信州大学, 学術研究院医学系, 助教 2011 – 2013: 信州大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Clinical oncology Except Principal Investigator General physiology / Pediatrics / Immunology
Keywords	Principal Investigator IL-2レセプターγ鎖 / insertional mutagenesis / Ｘ連鎖重症複合免疫不全症 / レトロウイルスベクター / 遺伝子治療 Except Principal Investigator 小胞輸送シグナル / ユビキチン / サイトカイン受容体 / 小胞輸送 / ユビキチン非依存性小胞輸送 … More / インターロイキン４受容体 / インターロイキン２受容体 / 受容体遺伝子多型 / アレルギー / サイトカイン / エンドソーム Less

Endosomal sorting signal of cytokine receptors and its single nucleotide polymorphism in allergy disease
- Principal Investigator
  
  TAKESHITA Toshikazu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Ubiquitin-independent endosomal sorting of cytokine receptors
- Principal Investigator
  
  AMANO Yuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Shinshu University
Identification of the cell type specific region for retroviral vector integrationPrincipal Investigator
- Principal Investigator
  
  YOSHINO kazuhisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Shinshu University
Identification of ubiquitin-dependent endosomal sorting signal in cytokine receptors
- Principal Investigator
  
  TAKESHITA Toshikazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Shinshu University

All 2014 2013 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation2014
- Author(s)
  Kojima, K., Amano, Y., Yoshino, K., Tanaka, N., Sugamura, K., Takeshita, T.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 48 Pages: 33296-33310
- DOI
  10.1074/jbc.m114.578245
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-25461586, KAKENHI-PROJECT-25860161
[Journal Article] A hydrophobic amino acid cluster inserted into the C-terminus of a recycling cell surface receptor functions as an endosomal sorting signal2013
- Author(s)
  Amano Y., Yoshino K., Kojima K., Takeshita T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 441 Issue: 1 Pages: 164-168
- DOI
  10.1016/j.bbrc.2013.10.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701099, KAKENHI-PROJECT-25461586, KAKENHI-PROJECT-25860161
[Journal Article] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011
- Author(s)
  Amano Y, Yamashita Y, Tanaka N, Sugamura K, 他
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 17 Pages: 15458-15472
- DOI
  10.1074/jbc.m110.191924
- NAID
  120007110518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590517, KAKENHI-PROJECT-21590530, KAKENHI-PROJECT-22591925
[Journal Article] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011
- Author(s)
  Amano Y.,Yamashita Y., Kojima K., Yoshino K., Tanaka N., Sugamura K., Takeshita T.
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 15458-15472
- NAID
  120007110518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701099
[Presentation] Hydrophobic amino acid cluster in the cytoplasmic tail of interleukin-2 receptor β chain acts as a sorting signal for lysosome2013
- Author(s)
  Amano Y., Kojima K., Yoshino K., Takeshita T.
- Organizer
  国際免疫学会
- Place of Presentation
  ミラノ
- Year and Date
  2013-08-23
- Data Source
  KAKENHI-PROJECT-23701099
[Presentation] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011
- Author(s)
  天野勇治、小嶋克彦、吉野和寿、竹下敏一
- Organizer
  日本免疫学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-23701099
[Presentation] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011
- Author(s)
  天野勇治、小嶋克彦、吉野和寿、竹下敏一
- Organizer
  日本免疫学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21590530
[Presentation] Identification of Hrs-binding motif in the cytokine receptors delivered to lysosome in ubiquitin-independent manner2010
- Author(s)
  天野勇治、小嶋克彦、山下勇毅、吉野和寿、竹下敏一
- Organizer
  国際免疫学会
- Place of Presentation
  神戸
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21590530
[Presentation] Identification of Hrs-binding motif in the cytokine receptors delivered to lysosome in ubiquitin-independent manner2010
- Author(s)
  天野勇治、小嶋克彦、山下勇毅、吉野和寿、竹下敏一
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590530
[Presentation] ユビキチン非依存的に小胞輸送されるサイトカイン受容体のHrs会合モチーフの同定2009
- Author(s)
  天野勇治、小嶋克彦、山下勇毅、吉野和寿、竹下敏一
- Organizer
  日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21590530
[Presentation] 細胞内小胞輸送と細胞増殖におけるIL-2受容体β鎖のHrs結合領域の役割2009
- Author(s)
  山下勇毅、小嶋克彦、天野勇治、吉野和寿、竹下敏一
- Organizer
  日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21590530
[Presentation] Hydrophobic amino acid cluster in the cytoplasmic tail of interleukin-2 receptor β chain acts as a sorting signal for lysosome
- Author(s)
  天野勇治、小嶋克彦、吉野和寿、竹下敏一
- Organizer
  国際免疫学会
- Place of Presentation
  ミラノ（イタリア）
- Data Source
  KAKENHI-PROJECT-23701099

1. TAKESHITA Toshikazu (60212023)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. KOJIMA Katsuhiko (80345743)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. AMANO Yuji (50624681)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. 菅村和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 田中伸幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

YOSHINO Kazuhisa 吉野 和寿

Research Projects

Research Products

Co-Researchers

Endosomal sorting signal of cytokine receptors and its single nucleotide polymorphism in allergy disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ubiquitin-independent endosomal sorting of cytokine receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of the cell type specific region for retroviral vector integrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of ubiquitin-dependent endosomal sorting signal in cytokine receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A hydrophobic amino acid cluster inserted into the C-terminus of a recycling cell surface receptor functions as an endosomal sorting signal2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011

Author(s)

Journal Title

NAID

Data Source

[Presentation] Hydrophobic amino acid cluster in the cytoplasmic tail of interleukin-2 receptor β chain acts as a sorting signal for lysosome2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Identification of Hrs-binding motif in the cytokine receptors delivered to lysosome in ubiquitin-independent manner2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Identification of Hrs-binding motif in the cytokine receptors delivered to lysosome in ubiquitin-independent manner2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ユビキチン非依存的に小胞輸送されるサイトカイン受容体のHrs会合モチーフの同定2009

YOSHINO Kazuhisa 吉野和寿