Morohashi Yuichi 諸橋雄一

… Alternative Names

MOROHASHI Yuichi 諸橋雄一

Less

Researcher Number	40568169
Affiliation (Current)	2025: 沖縄科学技術大学院大学, 臨界期の神経メカニズム研究ユニット, 技術員
Affiliation (based on the past Project Information) *help	2012 – 2013: 東京大学, 薬学研究科(研究院), 助教 2010 – 2011: 東京大学, 大学院・薬学系研究科, 助教
Review Section/Research Field	Principal Investigator Biological pharmacy
Keywords	Principal Investigator 細胞生物学 / エンドサイトーシス / 細胞内小胞輸送 / βアミロイド産生 / アルツハイマー病 / 小胞輸送 / 酵素 / 薬学 / 脳神経疾患

遺伝学的危険因子ＰＩＣＡＬＭとＢＩＮ１がアルツハイマー病発症に果たす役割の解明Principal Investigator
- Principal Investigator
  
  諸橋雄一
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Mechanism of substrate selectivity of gamma-secretase regulated by membrane traffickingPrincipal Investigator
- Principal Investigator
  
  MOROHASHI Yuichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Protein trafficking and maturation regulates intramembrane proteolysis.2013
- Author(s)
  Morohashi Y, Tomita T
- Journal Title
  
  BBA-Biomembranes
  
  Volume: 1828 Issue: 12 Pages: 2855-2861
- DOI
  10.1016/j.bbamem.2013.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111511, KAKENHI-PROJECT-24590076
[Journal Article] Neutralization of Gamma-secretase Activity by Monoclonal Antibody against Extracellular Domain of Nicastrin2012
- Author(s)
  Hayashi I, Morohashi Y, et al.
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 787-798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790061
[Journal Article] アルツハイマー病の分子標的治療法2010
- Author(s)
  諸橋雄一
- Journal Title
  
  日本臨床
  
  Volume: 68 Pages: 1906-1910
- Data Source
  KAKENHI-PROJECT-22790061
[Journal Article] Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C2010
- Author(s)
  Hsu C, Morohashi Y, et al.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 189 Pages: 223-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790061
[Journal Article] Phosphorylation and membrane dissociation of the ARF exchange factor GBF1 in mitosis2010
- Author(s)
  Morohashi Y, et al.
- Journal Title
  
  Biochemical Journal
  
  Volume: 427 Pages: 401-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] PICALM impacts on Aβ42 production ratio through modulation of clathrin-mediated endocytosis of γ-secretase2012
- Author(s)
  金津邦彦　諸橋雄一　他
- Organizer
  日本認知症学会
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-24590076
[Presentation] BIN1 negatively modulates Aβ production from cultured cells.2012
- Author(s)
  Miyagawa T, Morohashi Y et al.
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24590076
[Presentation] PICALM impacts the production and secretion of Aβ42 in cultured cells2011
- Author(s)
  Morohashi Y, et al.
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Identification and functional analysisof a genetic regulator forγ-secretasesubstrate trafficking2011
- Author(s)
  一色隼,山下雄大,石渡智之,諸橋雄一,富田泰輔,岩坪威
- Organizer
  第6回日本Notch研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Identification and functional analysisof a genetic regulator forγ-secretasesubstrate trafficking2011
- Author(s)
  一色隼人,山下雄大,石渡智之,諸橋雄一,富田泰輔,岩坪威
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2011
- Author(s)
  石渡智之,一色隼人,桑原知樹,諸橋雄一,三谷昌平,富田泰輔,岩坪威
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2011
- Author(s)
  石渡智之,一色隼人,桑原知樹,諸橋雄一,三谷昌平,富田泰輔,岩坪威
- Organizer
  第6回日本Notch研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2010
- Author(s)
  石渡智之,一色隼人,桑原知樹,諸橋雄一,三谷昌平,富田泰輔,岩坪威
- Organizer
  第5回Notch研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Neutralization of Gamma-secretase Activity by Monoclonal Antibody against Extracellular Domain of Nicastrin2010
- Author(s)
  諸橋雄一
- Organizer
  The 10th International Congress on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2010-03-11
- Data Source
  KAKENHI-PROJECT-22790061
[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2010
- Author(s)
  石渡智之,一色隼人,桑原知樹,諸橋雄一,三谷昌平,富田泰輔,岩坪威
- Organizer
  4^<th> East Asia C. elegans Meeting
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790061

1. IWATSUBO Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. TOMITA Taisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Morohashi Yuichi 諸橋 雄一

MOROHASHI Yuichi 諸橋 雄一

Research Projects

Research Products

Co-Researchers

遺伝学的危険因子ＰＩＣＡＬＭとＢＩＮ１がアルツハイマー病発症に果たす役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of substrate selectivity of gamma-secretase regulated by membrane traffickingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Protein trafficking and maturation regulates intramembrane proteolysis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neutralization of Gamma-secretase Activity by Monoclonal Antibody against Extracellular Domain of Nicastrin2012

Author(s)

Journal Title

Data Source

[Journal Article] アルツハイマー病の分子標的治療法2010

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C2010

Author(s)

Journal Title

Data Source

[Journal Article] Phosphorylation and membrane dissociation of the ARF exchange factor GBF1 in mitosis2010

Author(s)

Journal Title

Data Source

[Presentation] PICALM impacts on Aβ42 production ratio through modulation of clathrin-mediated endocytosis of γ-secretase2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] BIN1 negatively modulates Aβ production from cultured cells.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] PICALM impacts the production and secretion of Aβ42 in cultured cells2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Identification and functional analysisof a genetic regulator forγ-secretasesubstrate trafficking2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Identification and functional analysisof a genetic regulator forγ-secretasesubstrate trafficking2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Functional analysis of SFT-4 in the C. elegans Notch pathway2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Neutralization of Gamma-secretase Activity by Monoclonal Antibody against Extracellular Domain of Nicastrin2010

Morohashi Yuichi 諸橋雄一

MOROHASHI Yuichi 諸橋雄一