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MIZUNO SHINICHI  水野 晋一

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… Alternative Names

水野 晋一  ミズノ シンイチ

MIZUNO Shinichi  水野 晋一

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Researcher Number 40569430
Affiliation (Current) 2025: 九州大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 九州大学, 医学研究院, 教授
2018: 九州大学, 医学研究院, 教授
2016 – 2017: 九州大学, 先端医療イノベーションセンター, 特任准教授
2012 – 2015: 九州大学, 先端医療イノベーションセンター, 准教授
2011: 久留米大学, 医学部, 講師
2010: 久留米大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Tumor diagnostics / Tumor diagnosis / Hematology
Except Principal Investigator
Hematology / Life / Health / Medical informatics
Keywords
Principal Investigator
腫瘍進展 / 腫瘍発生 / マクロファージ / 免疫監視 / クローン造血 / ゲノム構造異常 / ゲノム解析 / バイオテクノロジー / 癌 / ゲノム … More / 発現解析 / 免疫学 / 発生・分化 / 発現制御 / 血液免疫学 … More
Except Principal Investigator
遺伝子解析 / 造血幹細胞移植 / 造血幹細胞移植学 / マイナー組織適合性抗原 / 組織適合抗原 / シークエンスデータ / HLA / 階層ベイズモデル / 免疫ゲノム / マルコフ連鎖モンテカルロ / がんゲノム / HLA遺伝子型 / ベイズモデル / 白血病再発 / ドナー由来白血病 / 白血病 / ゲノム / 癌 / 染色体転座 / 造血器悪性腫瘍 / 遺伝子変異 / 血液腫瘍学 Less
  • Research Projects

    (8 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (9 People)
  •  クローン造血(CH)環境の腫瘍発生・進展への機序およびCH環境の免疫学的制御Principal Investigator

    • Principal Investigator
      水野 晋一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyushu University
  •  Identification of novel minor histocompatibility antigens by next-generation sequencing in allogeneic stem cell transplantation patients

    • Principal Investigator
      Koji Nagafuji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kurume University
  •  Hierarchical Bayesian method for analyzing high polymorphic HLA genome sequence

    • Principal Investigator
      Imoto Seiya
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Life / Health / Medical informatics
    • Research Institution
      The University of Tokyo
  •  Molecular analysis of donor cells of pre- and post- bone marrow transplantation for the analysis of the underlying mechanism of leukemia of donor cell origin

    • Principal Investigator
      Nagafuji Koji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kurume University
  •  Development of a novel method for comprehensive analysis of structural changes of cancer genomePrincipal Investigator

    • Principal Investigator
      MIZUNO SHINICHI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kyushu University
  •  Comprehensive genetic analysis identifying novel genetic abnormalities responsible for myeloproliferative neoplasm

    • Principal Investigator
      OKAMURA TAKASHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kurume University
  •  The role of post-transcriptional control of Notch1gene in self- renewal and T-cell differentiation of hematopoieticstem cellsPrincipal Investigator

    • Principal Investigator
      MIZUNO Shinichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kyushu University
      Kurume University
  •  Development of a novel method for discovering fusion genes causative for tumorigenesisPrincipal Investigator

    • Principal Investigator
      MIZUNO Shinichi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnosis
    • Research Institution
      Kurume University

All 2024 2023 2022 2017 2015 2014 2013 2012 2011 2010

All Journal Article Presentation Book Patent

  • [Book] 実験医学 がん免疫療法×ゲノミクスで変わるがん治療2017

    • Author(s)
      井元清哉、山口類、水野晋一、中川英刀
    • Total Pages
      137
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-15H02775
  • [Journal Article] Prognostic impact of HLA supertype mismatch in single-unit cord blood transplantation2024

    • Author(s)
      Sugio T, Uchida N, Miyawaki K, Ohno Y, Eto T, Mori Y, Yoshimoto G, Kikushige Y, Kunisaki Y, Mizuno S, Nagafuji K, Iwasaki H, Kamimura T, Ogawa R, Miyamoto T, Taniguchi S, Akashi K, Kato K.
    • Journal Title

      Bone Marrow Transplant

      Volume: 59 Issue: 4 Pages: 466-472

    • DOI

      10.1038/s41409-023-02183-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364
  • [Journal Article] Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers2023

    • Author(s)
      Kobayashi Y, Niida A, Nagayama S, Saeki K, (中略), Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K.
    • Journal Title

      Br J Cancer

      Volume: 129 Issue: 7 Pages: 1105-1118

    • DOI

      10.1038/s41416-023-02395-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-23K24164
  • [Journal Article] Three-dimensional topological radiogenomics of epidermal growth factor receptor Del19 and L858R mutation subtypes on computed tomography images of lung cancer patients2023

    • Author(s)
      Ninomiya Kenta、Arimura Hidetaka、Tanaka Kentaro、Chan Wai Yee、Kabata Yutaro、Mizuno Shinichi、Gowdh Nadia Fareeda Muhammad、Yaakup Nur Adura、Liam Chong-Kin、Chai Chee-Shee、Ng Kwan Hoong
    • Journal Title

      Computer Methods and Programs in Biomedicine

      Volume: Epub ahead of print Pages: 107544-107544

    • DOI

      10.1016/j.cmpb.2023.107544

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08084, KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21K18312, KAKENHI-PROJECT-20K14312
  • [Journal Article] CT Image-Based Biopsy to Aid Prediction of HOPX Expression Status and Prognosis for Non-Small Cell Lung Cancer Patients2023

    • Author(s)
      Jin Yu、Arimura Hidetaka、Cui YunHao、Kodama Takumi、Mizuno Shinichi、Ansai Satoshi
    • Journal Title

      Cancers

      Volume: 15 Issue: 8 Pages: 2220-2220

    • DOI

      10.3390/cancers15082220

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23KJ1733, KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-20K08084
  • [Journal Article] RHAMM marks proliferative subpopulation of human colorectal cancer stem cells2023

    • Author(s)
      Nakano Michitaka、Taguchi Ryosuke、Kikushige Yoshikane、Isobe Taichi、Miyawaki Kohta、Mizuno Shinichi、Tsuruta Nobuhiro、Hanamura Fumiyasu、Yamaguchi Kyoko、Yamauchi Takuji、Ariyama Hiroshi、Kusaba Hitoshi、Nakamura Masafumi、Maeda Takahiro、Kuo Calvin J.、Baba Eishi、Akashi Koichi
    • Journal Title

      Cancer Science

      Volume: - Issue: 7 Pages: 15795-12

    • DOI

      10.1111/cas.15795

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-19K16852
  • [Journal Article] Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions.2022

    • Author(s)
      Ito M, Nakano M, Ariyama H, Yamaguchi K, Tanaka R, Semba Y, Sugio T, Miyawaki K, Kikushige Y, Mizuno S, Isobe T, Tanoue K, Taguchi R, Ueno S, Kawano T, Murata M, Baba E, Akashi K.
    • Journal Title

      Cancer Lett.

      Volume: 532 Pages: 215597-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07153
  • [Journal Article] Immunomodulatory Cell Therapy Using αGalCer-Pulsed Dendritic Cells Ameliorates Heart Failure in a Murine Dilated Cardiomyopathy Model.2022

    • Author(s)
      Ikeda M, Ide T, Matsushima S, Ikeda S, Okabe K, Ishikita A, Tadokoro T, Sada M, Abe K, Sato M, Hanada A, Arai S, Ohtani K, Nonami A, Mizuno S, Morimoto S, Motohashi S, Akashi K, Taniguchi M, Tsutsui H.
    • Journal Title

      Circ Heart Fail.

      Volume: 15 Issue: 12 Pages: 1125-1139

    • DOI

      10.1161/circheartfailure.122.009366

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21K08082, KAKENHI-PROJECT-21K16090, KAKENHI-PROJECT-21K19485, KAKENHI-PROJECT-21K16026, KAKENHI-PROJECT-23K24441
  • [Journal Article] Prospective study of adoptive activated αβT lymphocyte immunotherapy for refractory cancers: development and validation of a response scoring system.2022

    • Author(s)
      Nonami A, Matsuo R, Funakoshi K, Nakayama T, Goto S, Iino T, Takaishi S, Mizuno S, Akashi K, Eto M.
    • Journal Title

      Cytotherapy.

      Volume: 25 Pages: 76-81

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07153
  • [Journal Article] Notch1 expression is regulated at the post-transcriptional level by the 3′ untranslated region in hematopoietic stem cell development2017

    • Author(s)
      Mizuno Shinichi、Iino Tadafumi、Ozawa Hidetoshi、Arinobu Yojiro、Chong Yong、Akashi Koichi
    • Journal Title

      International Journal of Hematology

      Volume: 107 Issue: 3 Pages: 311-319

    • DOI

      10.1007/s12185-017-2358-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09883, KAKENHI-PROJECT-16K09897, KAKENHI-PROJECT-15K15365
  • [Journal Article] p600 Plays Essential Roles in Fetal Development2014

    • Author(s)
      (*: equally contributed) *Nakaya T., *Ishiguro K., Belzil C., Rietsch A.M., Yu Q., Mizuno S., Bronson R.T., Geng Y., Nguyen M.D., Akashi K., Sicinski P., Nakatani Y.
    • Journal Title

      Plos One

      Volume: 8 Issue: 6 Pages: e66269-e66269

    • DOI

      10.1371/journal.pone.0066269

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24114503, KAKENHI-PROJECT-25640078
  • [Journal Article] A case of 8p11 myeloproliferative syndrome with BCR-FGFR1 gene fusion presenting with trilineage acute leukemia/lymphoma, successfully treated by cord blood transplantation2013

    • Author(s)
      Morishige S, Oku E, Mizuno S, Okamura T
    • Journal Title

      Acta Haematol

      Volume: 129 Issue: 2 Pages: 83-89

    • DOI

      10.1159/000341289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390196, KAKENHI-PROJECT-23390255, KAKENHI-PROJECT-23659313, KAKENHI-PROJECT-25640078, KAKENHI-PROJECT-25670542
  • [Journal Article] Unrelated cord blood transplantation for patients with adult T-cell leukemia/lymphoma: experience at a single institute2012

    • Author(s)
      Nakamura T, Oku E, Mizuno S, Okamura T
    • Journal Title

      Int J Hematol

      Volume: 96 Issue: 5 Pages: 657-663

    • DOI

      10.1007/s12185-012-1177-8

    • NAID

      10031126764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390196, KAKENHI-PROJECT-22790363, KAKENHI-PROJECT-23390255, KAKENHI-PROJECT-23659313
  • [Patent] METHOD FOR PRODUCING CIRCULAR DNA FORMED FROM SINGLE-MOLECULE DNA2013

    • Inventor(s)
      Mizuno, Nagafuji, Okamura
    • Industrial Property Rights Holder
      Mizuno, Nagafuji, Okamura
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-06-27
    • Acquisition Date
      2015-02-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25640078
  • [Patent] METHOD FOR EXCUSIVE SELECTION OF CIRCULARIZED DNA FROM MONOMOLECULAR DAN WHEN CIRCULARIZING DNA MOLECULES2012

    • Inventor(s)
      MIZUNO Shinichi, OZAWA Hidetoshi, NAGAFUJI Koji, OKAMURA Takashi
    • Industrial Property Rights Holder
      KURUME UNIVERSITY
    • Filing Date
      2012-08-24
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Patent] METHOD FOR EXCLUSIVE SELECTION OF CIRCULARIZED DNA FROM MONOMOLECULAR DNA WHEN CIRCULARIZING DNA MOLECULES2012

    • Inventor(s)
      MIZUNO Shinichi, OZAWA Hidetoshi, NAGAFUJI Koji, OKAMURA Takashi
    • Industrial Property Rights Holder
      KURUME UNIVERSITY
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-08-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23390255
  • [Patent] DNA分子の環状化において単分子による環状化DNAのみを選別する方法2011

    • Inventor(s)
      水野晋一、小澤秀俊、長藤宏司、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Filing Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22650234
  • [Patent] DNA分子の環状化において単分子による環状化DNAのみを選別する方法2011

    • Inventor(s)
      水野晋一, 小澤秀俊, 長藤宏司, 岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2011-189280
    • Filing Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-23390255
  • [Patent] DNA分子の環状化において単分子による環状化DNAのみを選別する方法2011

    • Inventor(s)
      水野晋一、小澤秀俊、長藤宏司、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Number
      2011-189280
    • Filing Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Patent] METHOD FOR PRODUCING CIRCULAR DNA FORMED FROM SINGLE-MOLECULE DNA2011

    • Inventor(s)
      MIZUNO Shinichi, NAGAFUJI Koji, OKAMURA Takashi
    • Industrial Property Rights Holder
      KURUME UNIVERSITY
    • Filing Date
      2011-08-22
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Patent] DNA分子の環状化において単分子による環状化DNAのみを選別する方法2011

    • Inventor(s)
      水野晋一、小澤秀俊、長藤宏司、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Number
      2011-189280
    • Filing Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-23390255
  • [Patent] DNA 分子の環状化において単分子による環状化 DNA のみを選別する方法2011

    • Inventor(s)
      水野晋一、小澤秀俊、長藤宏司、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Number
      2011-189280
    • Filing Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Patent] DNA分子の環状化において単分子による環状化DNAのみを選別する方法2011

    • Inventor(s)
      水野晋一、小澤秀俊、長藤宏司、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Number
      2011-189280
    • Filing Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-22650234
  • [Patent] METHOD FOR PRODUCING CIRCULAR DNA FORMED FROM SINGLE-MOLECULE DNA2011

    • Inventor(s)
      MIZUNO Shinichi, NAGAFUJI Koji, OKAMURA Takashi
    • Industrial Property Rights Holder
      KURUME UNIVERSITY
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-08-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23390255
  • [Patent] 単分子DNAから形成される環状DNAの作成方法2010

    • Inventor(s)
      水野晋一、長藤宏治、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Filing Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22650234
  • [Patent] 単分子 DNA から形成される環状 DNA の作成方法2010

    • Inventor(s)
      水野晋一、小澤秀俊、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Number
      2010-196719
    • Filing Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Patent] 単分子DNAから形成される環状DNAの作成方法2010

    • Inventor(s)
      水野晋一、長藤宏司、岡村孝
    • Industrial Property Rights Holder
      久留米大学
    • Industrial Property Number
      2010-196719
    • Filing Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22650234
  • [Presentation] Bayesian Method for HLA Genotyping from Whole-Genome Sequencing Data2015

    • Author(s)
      Shuto Hayashi, Rui Yamaguchi, Shinichi Mizuno, Mitsuhiro Komura, Satoru Miyano, Hidewaki Nakagawa, Seiya Imoto
    • Organizer
      2015 International Workshop on Bioinformatics and Systems Biology
    • Place of Presentation
      Boston, USA
    • Year and Date
      2015-07-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02775
  • [Presentation] 新しい遺伝子検査法-がん融合遺伝子の新規探索法-2012

    • Author(s)
      水野晋一
    • Organizer
      BIO tech 2012
    • Place of Presentation
      東京
    • Year and Date
      2012-04-26
    • Data Source
      KAKENHI-PROJECT-22650234
  • [Presentation] 癌融合遺伝子の新規探索法-新しい遺伝子検査法-2011

    • Author(s)
      水野晋一
    • Organizer
      BioJapan 2012
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-10-10
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Presentation] 新しい遺伝子検査法-がん融合遺伝子の新規探索法-2011

    • Author(s)
      水野晋一
    • Organizer
      Bio Japan 2011
    • Place of Presentation
      横浜
    • Year and Date
      2011-10-07
    • Data Source
      KAKENHI-PROJECT-22650234
  • [Presentation] 新しい遺伝子検査法-がん融合遺伝子の新規探索法-2011

    • Author(s)
      水野晋一
    • Organizer
      BioJapan 2011
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-10-07
    • Data Source
      KAKENHI-PROJECT-22390196
  • [Presentation] 新しい遺伝子検査法-がん融合遺伝子の新規探索法-2011

    • Author(s)
      水野晋一
    • Organizer
      BioJapan 2011
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-10-07
    • Data Source
      KAKENHI-PROJECT-22650234
  • 1.  OKU Eijiro (10569429)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  Nagafuji Koji (60343323)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  OKAMURA TAKASHI (30136436)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Imoto Seiya (10345027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  ISHIGURO Kei-ichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  有村 秀孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  田中 謙太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  菊繁 吉謙
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  磯部 大地
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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