• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Ohata Hirokazu  大畑 広和

ORCIDConnect your ORCID iD *help
… Alternative Names

OHATA Hirokazu  大畑 広和

Less
Researcher Number 40570057
Other IDs
Affiliation (Current) 2025: 帝京大学, 先端総合研究機構, 講師
2025: 国立研究開発法人国立がん研究センター, 研究所, 外来研究員
Affiliation (based on the past Project Information) *help 2022 – 2023: 帝京大学, 先端総合研究機構, 講師
2020 – 2021: 国立研究開発法人国立がん研究センター, 研究所, 研究員
2016 – 2017: 国立研究開発法人国立がん研究センター, 研究所, 研究員
2012 – 2013: 独立行政法人国立がん研究センター, 研究所, 研究員
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Basic Section 55020:Digestive surgery-related
Keywords
Principal Investigator
がん幹細胞 / 治療抵抗性 / 癌 / シングルセル遺伝子発現解析 / カリウムチャネル / 大腸がん / CD44
  • Research Projects

    (4 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (1 People)
  •  抗がん剤抵抗性を示す休止型大腸がん幹細胞を標的にした治療戦略の構築Principal Investigator

    • Principal Investigator
      大畑 広和
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Teikyo University
  •  Autophagy provides a quiescent state in colon cancer stem cellsPrincipal Investigator

    • Principal Investigator
      Ohata Hirokazu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Teikyo University
      National Cancer Center Japan
  •  Identification of functional potassium channels in colon cancer stem cellsPrincipal Investigator

    • Principal Investigator
      Ohata Hirokazu
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      National Cancer Center Japan
  •  Analysis of mechanism of maintaining the stemness properties in human colon cancer stem cells using innovative spheroid culture systemPrincipal Investigator

    • Principal Investigator
      OHATA Hirokazu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      National Center of Neurology and Psychiatry

All 2023 2022 2020 2013 2012 Other

All Journal Article Presentation Book Other

  • [Book] 治療標的としてのがん幹細胞2020

    • Author(s)
      伊藤 貴浩、大畑 広和
    • Total Pages
      128
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-20K09023
  • [Journal Article] PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway2023

    • Author(s)
      Ohata Hirokazu、Shiokawa Daisuke、Sakai Hiroaki、Kanda Yusuke、Okimoto Yoshie、Kaneko Syuzo、Hamamoto Ryuji、Nakagama Hitoshi、Okamoto Koji
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 6 Pages: 112519-112519

    • DOI

      10.1016/j.celrep.2023.112519

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-23K07467, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-21H03550
  • [Journal Article] Induction of the stem-like cell regulator CD44 by Rho kinase inhibiition con ntributes to the mmaintenance of colon-initiating cells2012

    • Author(s)
      Hirokazu Ohata, Tatsuyya Ishiguro, Yuki Aihhara, Ai Sato, Hiroaki Sakai, Shgeki Sekine, Hirokkazu Taniguchi. Takayuki Akasu, Shin Fujita, Hitoshi Nakagama, , Koji Okaamoto
    • Journal Title

      Cancer Research

      Volume: vol.72 Pages: 5101-55110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790727
  • [Presentation] PROX1 induction by autophagy provides a persister-like state via repression of NOX1-mTORC1 pathway in colon cancer cells2022

    • Author(s)
      Hirokazu Ohata, Daisuke Shiokawa, Koji Okamoto
    • Organizer
      第81回日本癌学会
    • Data Source
      KAKENHI-PROJECT-20K09023
  • [Presentation] 大腸がん幹細胞における Akt-mTOR経路を介したCD44の発現制御機構2013

    • Author(s)
      大畑広和、中釜斉、岡本康司
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24790727
  • [Presentation] 大腸がん幹細胞におけるAkt-mTOR経路を介したCD44の発現制御機構2013

    • Author(s)
      大畑広和、中釜斉、岡本康司
    • Organizer
      第72回 日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24790727
  • [Presentation] ROCK阻害剤は CD44の発現誘導を介して大腸がん幹細胞の増殖を促進する2012

    • Author(s)
      大畑広和、石黒竜也、中釜斉、岡本康司
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24790727
  • [Presentation] ROCK阻害剤はCD44の発現誘導を介して大腸がん幹細胞の増殖を促進する2012

    • Author(s)
      大畑広和、石黒竜也、中釜斉、岡本康司
    • Organizer
      第71回 日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24790727
  • []

  • []

  • []

  • []

  • []

  • []

  • []

  • 1.  塩川 大介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi